O=C(NCc1cn2cc(CNCC3CCCCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5291234 Kd 1.4 nM
COc1cc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5396973 IC50 3.63 nM
Oc1cc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5438009 IC50 4.23 nM
Clc1cc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5405105 IC50 4.35 nM
Brc1cc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5425488 IC50 4.44 nM
COc1cc2c(cc1Cc1cccc(Cl)c1F)c(=O)c(C(=O)O)cn2[C@H](CO)C(C)C CHEMBL204656 Kd 4.79 nM
CNc1cc(N2CCC3(CC2)CN(c2cc(F)c(CN4CCC(C)(C)CC4)cc2F)CC(=O)N3)ncn1 CHEMBL5077332 IC50 5.0 nM
Fc1cc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5412324 IC50 5.67 nM
CC1(C)CCN(Cc2ccc3nc(Cn4cc(-c5cccc6[nH]ncc56)nn4)cn3c2)CC1 CHEMBL5423596 IC50 5.76 nM
c1cc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5433927 IC50 5.776 nM
OC1(CNCc2ccc3nc(Cn4cc(-c5cc(Br)cc6[nH]ncc56)nn4)cn3c2)CCCCC1 CHEMBL5433144 IC50 5.8 nM
OC1(CNCc2ccc3nc(Cn4cc(-c5cc(Cl)cc6[nH]ncc56)nn4)cn3c2)CCC1 CHEMBL5407802 IC50 5.92 nM
Fc1ccc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)c2cn[nH]c12 CHEMBL5404800 IC50 6.009 nM
COc1ccc2[nH]ncc2c1-c1cn(Cc2cn3cc(CNCC4CCC4)ccc3n2)nn1 CHEMBL5417468 IC50 6.1 nM
O=C(NCc1cn2cc(CNCC34CC(F)(C3)C4)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5410561 IC50 6.1 nM
OC1(CNCc2ccc3nc(Cn4cc(-c5cc(Br)cc6[nH]ncc56)nn4)cn3c2)CCC1 CHEMBL5413095 IC50 6.1 nM
CC(C)(C)CNCc1ccc2nc(Cn3cc(-c4cc(Cl)cc5[nH]ncc45)nn3)cn2c1 CHEMBL5424750 IC50 6.1 nM
COc1cc(-c2cn(Cc3cn4cc(CNCC5(OC)CCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5419185 IC50 6.1 nM
Nc1ncnc2c1c(-c1cc[nH]n1)cn2[C@@H]1O[C@H](/C=C/CCCNCC23CC(F)(C2)C3)[C@@H](O)[C@H]1O CHEMBL5403823 IC50 6.1 nM
Nc1ncnc2c1c(F)cn2[C@@H]1C[C@H](c2ccc3cc(CNCC45CC(F)(C4)C5)[nH]c3c2)[C@@H](O)[C@H]1O CHEMBL5414110 IC50 6.1 nM
Nc1ncnc2c1c(Cl)cn2[C@@H]1C[C@H](c2ccc3cc(CNCC45CC(F)(C4)C5)[nH]c3c2)[C@@H](O)[C@H]1O CHEMBL5398269 IC50 6.1 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1C[C@H](c2ccc3cc(CN4CCC5(CCC5)C4)[nH]c3c2)[C@@H](O)[C@H]1O CHEMBL5415737 IC50 6.1 nM
Fc1cc(-c2cn(Cc3cn4cc(CNCC5CCCCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5396238 IC50 6.156 nM
O=C(NCc1cn2cc(CNCC34CC(C3)C4)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5406441 IC50 6.19 nM
Nc1ncnc2c1ccn2[C@@H]1C[C@H](c2ccc3cc(CN4CCC5(CCC5)C4)[nH]c3c2)[C@@H](O)[C@H]1O CHEMBL5405801 IC50 6.22 nM
O=C(NCc1cn2cc(CNCC3CCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5407933 IC50 6.25 nM
CC(C)(C)CNCc1ccc2nc(Cn3cc(-c4cc(Br)cc5[nH]ncc45)nn3)cn2c1 CHEMBL5397256 IC50 6.69 nM
Fc1ccc(-c2cn(Cc3cn4cc(CNCC5CCCCC5)ccc4n3)nn2)c2cn[nH]c12 CHEMBL5413923 IC50 6.721 nM
Oc1cc(-c2cn(Cc3cn4cc(CNCC5(O)CCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5430735 IC50 6.95 nM
N#Cc1cc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5395686 IC50 7.49 nM
O=C(NCc1cn2cc(CNC[C@@H]3C[C@H]4CC[C@@H]3C4)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5433650 IC50 7.5 nM
O=C(NCc1cn2cc(CNC[C@H]3C[C@H](F)C3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5431636 IC50 7.58 nM
O=C(NCc1cn2cc(CNCC3CC4C=CC3C4)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5403599 IC50 7.68 nM
OC1(CNCc2ccc3nc(Cn4cc(-c5cc(F)cc6[nH]ncc56)nn4)cn3c2)CCC1 CHEMBL5395760 IC50 7.838 nM
CC1(C)CCN(Cc2ccc3nc(Cn4cc(-c5cc(Br)cc6[nH]ncc56)nn4)cn3c2)CC1 CHEMBL5402970 IC50 7.898 nM
FC1(F)CC(CNCc2ccc3nc(Cn4cc(-c5cc(Br)cc6[nH]ncc56)nn4)cn3c2)C1 CHEMBL5407449 IC50 8.02 nM
COc1cc(-c2cn(Cc3cn4cc(CNCC5(O)CCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5428895 IC50 8.05 nM
Brc1cc(-c2cn(Cc3cn4cc(CNCC5CCCCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5414237 IC50 8.145 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1C[C@H](c2ccc3[nH]c(CNCC45CC(F)(C4)C5)cc3c2)[C@@H](O)[C@H]1O CHEMBL5403748 IC50 8.24 nM
OC1(CNCc2ccc3nc(Cn4cc(-c5cccc6[nH]ncc56)nn4)cn3c2)CCCCC1 CHEMBL5422748 IC50 8.837 nM
c1cc2[nH]ncc2c(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)n1 CHEMBL5402416 IC50 8.857 nM
O=C(NCc1cn2cc(CNC[C@H]3C[C@H]4CC[C@@H]3C4)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5426163 IC50 9.02 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1C[C@H](c2ccc(CNCC34CC(F)(C3)C4)cc2)[C@@H](O)[C@H]1O CHEMBL5405292 IC50 9.11 nM
OC1(CNCc2ccc3nc(Cn4cc(-c5ccc(F)c6[nH]ncc56)nn4)cn3c2)CCCCC1 CHEMBL5399722 IC50 9.46 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/CCCNCC23CC(F)(C2)C3)C[C@H]1O CHEMBL5399334 IC50 9.6 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(-c5cnn(C)c5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5082853 IC50 10.0 nM
Nc1cc(C2CC2)nc2cc(OC[C@H]3O[C@@H](n4cc(Br)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)ccc12 CHEMBL5090301 IC50 10.0 nM
Nc1cc(N)c2ccc(OC[C@H]3O[C@@H](n4cc(C5CCCC5)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5081328 IC50 10.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(C5CCN(C)C5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5077553 IC50 10.0 nM
CCc1cc(N)c2ccc(OC[C@H]3O[C@@H](n4cc(Br)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5080767 IC50 10.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(C5CCN(C)CC5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5078397 IC50 10.0 nM
Cc1cc(N)c2ccc(OC[C@H]3O[C@@H](n4cc(Br)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5084566 IC50 10.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(C5=CCNC5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5080700 IC50 10.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(C5=CCN(C)CC5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5093663 IC50 10.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(-c5ccnn5C)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5086926 IC50 10.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(C(F)(F)F)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5078336 IC50 10.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(-c5cccnc5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5085179 IC50 10.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(C)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5077280 IC50 10.0 nM
CNc1ccc2ccc(OC[C@H]3C[C@@H](n4cc(C5CCCC5)c5c(N)ncnc54)C[C@@H]3O)cc2n1 CHEMBL5090116 IC50 10.0 nM
CNc1ccc2ccc(CC[C@H]3C[C@@H](n4cc(C5CCOCC5)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5085014 IC50 10.0 nM
Nc1ccc2ccc(CC[C@H]3C[C@@H](n4cc(C5CCCC5)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5085428 IC50 10.0 nM
Nc1ncnc2c1ccn2[C@@H]1O[C@H](CCc2ccc3ccc(N4CCCC4)nc3c2)[C@@H](O)[C@H]1O CHEMBL5069784 IC50 10.0 nM
CNc1ccc2cc(OC[C@H]3O[C@@H](n4cc(C)c5c(N)ncnc54)[C@H](O)[C@@H]3O)ccc2n1 CHEMBL5078534 IC50 10.0 nM
Nc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(Br)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5076753 IC50 10.0 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](COc2ccc3ccc(N4CCCC4)nc3c2)[C@@H](O)[C@H]1O CHEMBL5094336 IC50 10.0 nM
Nc1ncnc2c1ccn2[C@@H]1O[C@H](COc2ccc3ccc(N4CCCC4)nc3c2)[C@@H](O)[C@H]1O CHEMBL5089421 IC50 10.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5075540 IC50 10.0 nM
Nc1ncnc2c1ccn2[C@@H]1O[C@H](COc2ccc3ccc(N4CCOCC4)nc3c2)[C@@H](O)[C@H]1O CHEMBL5091678 IC50 10.0 nM
CN(C)c1ccc2ccc(OC[C@H]3O[C@@H](n4ccc5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5080001 IC50 10.0 nM
Nc1ccc2ccc(OC[C@H]3O[C@@H](n4ccc5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5075777 IC50 10.0 nM
CCNc1ccc2ccc(OC[C@H]3C[C@@H](n4ccc5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5093496 IC50 10.0 nM
CNc1ccc2cc(F)c(CC[C@H]3C[C@@H](n4ccc5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5079232 IC50 10.0 nM
CCNc1ccc2ccc(CC[C@H]3O[C@@H](n4ccc5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5086309 IC50 10.0 nM
CN(C)c1ccc2ccc(CC[C@H]3C[C@@H](n4ccc5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5076232 IC50 10.0 nM
Nc1ccc2ccc(CC[C@H]3C[C@@H](n4cc(Br)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5072465 IC50 10.0 nM
CC(C)Nc1ccc2ccc(CC[C@H]3C[C@@H](n4ccc5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5087274 IC50 10.0 nM
CCCC(=O)c1cn([C@@H]2O[C@H](COc3ccc4ccc(NC)nc4c3)[C@@H](O)[C@@H]2F)c2ncnc(N)c12 CHEMBL5078459 IC50 10.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(-c5cc(C)n(C)n5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5085740 IC50 10.0 nM
CCc1cc(N(C)C2CC2)c2ccc(OC[C@H]3O[C@@H](n4ccc5c(N)ncnc54)C[C@@H]3O)cc2n1 CHEMBL5091459 IC50 10.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](COc4ccc5sc(N6CCC6)nc5c4)[C@@H](O)[C@@H]3F)c3ncnc(N)c23)n1 CHEMBL5093423 IC50 10.0 nM
Nc1ncnc2c1ccn2[C@H]1C[C@H](O)[C@@H](COc2ccc3ccc(NC4CC4)nc3c2)O1 CHEMBL5088245 IC50 10.0 nM
Cc1ccn(-c2cn([C@@H]3O[C@H](COc4ccc5ccc(N6CC(N)C6)nc5c4)[C@@H](O)[C@@H]3F)c3ncnc(N)c23)n1 CHEMBL5075225 IC50 10.0 nM
Nc1ncnc2c1ccn2[C@@H]1O[C@H](COc2ccc3ccc(N4CC(N)C4)nc3c2)[C@@H](O)[C@@H]1F CHEMBL5073959 IC50 10.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](COc4ccc5ncc(N6CCC6)nc5c4)[C@@H](O)[C@@H]3F)c3ncnc(N)c23)n1 CHEMBL5086097 IC50 10.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](CCC4CCNCC4)[C@@H](O)[C@@H]3F)c3ncnc(N)c23)n1 CHEMBL5074595 IC50 10.0 nM
CNc1ccc2sc(CC[C@H]3O[C@@H](n4ccc5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5077847 IC50 10.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](COc4ccc5ccc(N[C@H]6C[C@H](N)C6)nc5c4)[C@@H](O)[C@@H]3F)c3ncnc(N)c23)n1 CHEMBL5093468 IC50 10.0 nM
Nc1ncnc2c1ccn2[C@H]1C[C@H](O)[C@@H](CCc2ccc3ccc(N4CCC4)nc3c2)O1 CHEMBL5085089 IC50 10.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](COc4ccc5cnc(N[C@H]6C[C@@H](N)C6)nc5c4)[C@@H](O)[C@@H]3F)c3ncnc(N)c23)n1 CHEMBL5075530 IC50 10.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](COc4ccc5cnc(NC6CC6)nc5c4)[C@@H](O)[C@@H]3F)c3ncnc(N)c23)n1 CHEMBL5080762 IC50 10.0 nM
CN(C)C(=O)c1cn([C@@H]2O[C@H](COc3ccc4ccc(N5CCC5)nc4c3)[C@@H](O)[C@@H]2F)c2ncnc(N)c12 CHEMBL5069561 IC50 10.0 nM
COCCN(C)C(=O)c1cn([C@@H]2O[C@H](COc3ccc4ccc(N5CCC5)nc4c3)[C@@H](O)[C@@H]2F)c2ncnc(N)c12 CHEMBL5085034 IC50 10.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(-c5cn(C(C)C)cn5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5085125 IC50 10.0 nM
CNc1ccc2ccc(OCc3cncc(-n4cc(C5CCC(F)(F)CC5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5086073 IC50 10.0 nM
CNc1ccc2ccc(OCc3cncc(-n4cc(C5CCCC5)c5c(N)ncnc54)n3)cc2n1 CHEMBL5075775 IC50 10.0 nM
CNc1ccc2ccc(OCc3cc(-n4cc(Cl)c5c(N)ncnc54)cnc3NC)cc2n1 CHEMBL5093009 IC50 10.0 nM
CNc1ccc2ccc(OCc3nc(-n4ccc5c(N)ncnc54)cs3)cc2n1 CHEMBL5076971 IC50 10.0 nM
CNc1ccc2ccc(COc3cncc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5077932 IC50 10.0 nM
Nc1ncnc2c1ccn2-c1cncc(COc2ccc3ccc(N4CCCC4)nc3c2)c1 CHEMBL5089709 IC50 10.0 nM
CNc1ccc2ccc(OCc3cncc(-n4cc(CCN(C)C)c5c(N)ncnc54)c3)cc2n1 CHEMBL5094631 IC50 10.0 nM
CNc1ccc2ccc(OCc3cc(-n4cc(Cl)c5c(N)ncnc54)cnc3N)cc2n1 CHEMBL5087856 IC50 10.0 nM
CNc1ccc2ccc(CCc3cncc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5091282 IC50 10.0 nM
CNc1ccc2ccc(OCc3cncc(-n4c(C)cc5c(N)ncnc54)c3)cc2n1 CHEMBL5082340 IC50 10.0 nM
CNc1ccc2ccc(OCc3nc(-n4cc(Cl)c5c(N)ncnc54)cs3)cc2n1 CHEMBL5089192 IC50 10.0 nM
CC(C)Nc1ccc2ccc(OCc3cncc(-n4cc(Cl)c5c(N)ncnc54)c3)cc2n1 CHEMBL5079341 IC50 10.0 nM
Nc1ncnc2c1c(Cl)cn2-c1cncc(COc2ccc3ccc(N4CCCC4)nc3c2)c1 CHEMBL5087281 IC50 10.0 nM
Cc1cc(NCCN(C)C)c2ccc(OCc3cncc(-n4cc(Cl)c5c(N)ncnc54)c3)cc2n1 CHEMBL5093518 IC50 10.0 nM
CNc1ccc2ccc(OCc3cccc(-n4cc(Br)c5c(N)ncnc54)c3)cc2n1 CHEMBL5084255 IC50 10.0 nM
CNc1ccc2ccc(OCc3cncc(-n4ccc5c(C)ncnc54)c3)cc2n1 CHEMBL5083248 IC50 10.0 nM
CNc1ccc2ccc(CCc3cncc(-n4cc(Cl)c5c(N)ncnc54)c3)cc2n1 CHEMBL5079121 IC50 10.0 nM
Cc1cc(N)c2ccc(OCc3cncc(-n4cc(Cl)c5c(N)ncnc54)c3)cc2n1 CHEMBL5069481 IC50 10.0 nM
CCNc1ccc2ccc(OCc3cccc(-n4cc(Cl)c5c(N)ncnc54)c3)cc2n1 CHEMBL5074676 IC50 10.0 nM
Cc1cc(N)c2ccc(OCc3cccc(-n4cc(Cl)c5c(N)ncnc54)c3)cc2n1 CHEMBL5079658 IC50 10.0 nM
CCc1ncc(-n2cc(Cl)c3c(N)ncnc32)cc1COc1ccc2ccc(NC)nc2c1 CHEMBL5075890 IC50 10.0 nM
CNc1ccc2ccc(OCc3cccc(-c4c[nH]c5c(N)ncnc45)c3)cc2n1 CHEMBL5075267 IC50 10.0 nM
CNc1ccc2ccc(OCc3cccc(-n4cc(C5CC5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5070418 IC50 10.0 nM
CNc1ccc2ccc(OCc3cc(F)cc(-n4cc(Cl)c5c(N)ncnc54)c3)cc2n1 CHEMBL5084083 IC50 10.0 nM
CNc1ccc2ccc(OCc3cccc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5092927 IC50 10.0 nM
CNc1ccc2ccc(OCc3cccc(-n4cc(CC5CC5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5079814 IC50 10.0 nM
CNc1ccc2ccc(OCc3cc(-n4cc(Cl)c5c(N)ncnc54)ccc3F)cc2n1 CHEMBL5079210 IC50 10.0 nM
CNc1ccc2ccc(OCc3cc(O)cc(-n4cc(Cl)c5c(N)ncnc54)c3)cc2n1 CHEMBL5078462 IC50 10.0 nM
CNc1ccc2ccc(OCc3cccc(-n4cc(Cl)c5c(N)ncnc54)n3)cc2n1 CHEMBL5092065 IC50 10.0 nM
CNc1ccc2ccc(OCc3cccc(-n4cc(C5CCCC5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5079874 IC50 10.0 nM
CNc1ccc2ccc(OCc3cccc(-n4cc(Cl)c5c(N)ncnc54)c3)cc2n1 CHEMBL5087122 IC50 10.0 nM
CC(C)c1nc(N)c2ccc(OCc3cncc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5084223 IC50 10.0 nM
CCCC(=O)c1cn(-c2cncc(COc3ccc4ccc(NC)nc4c3)c2)c2ncnc(N)c12 CHEMBL5073086 IC50 10.0 nM
Cc1cc(NCCN(C)CCCc2ccccc2)c2ccc(OCc3cncc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5080588 IC50 10.0 nM
Cc1cc(NCCN(C)CCCCc2ccccc2)c2ccc(OCc3cncc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5076578 IC50 10.0 nM
Cc1cc(NCCN(C)CCCCCc2ccccc2)c2ccc(OCc3cncc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5069882 IC50 10.0 nM
C[C@@H]1CCN1c1ccc2ccc(OCc3cncc(-n4cc(C5CCCC5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5091105 IC50 10.0 nM
C[C@H]1CCN1c1ccc2ccc(OCc3cncc(-n4cc(C5CCCC5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5076260 IC50 10.0 nM
CC(C)c1cc(N)c2ccc(CCc3cncc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5081266 IC50 10.0 nM
CC(C)c1cc(N)c2ccc(CCc3cncc(-n4cc(C5CCCC5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5090810 IC50 10.0 nM
CCc1cc(NCCOC)c2ccc(OCc3cncc(-n4cc([C@H]5CCCO5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5082083 IC50 10.0 nM
CCNc1ccc2ccc(CCc3cncc(-n4cc([C@H]5CCCO5)c5c(N)ncnc54)n3)cc2n1 CHEMBL5082387 IC50 10.0 nM
CCc1cc(N2CCOCC2)c2ccc(OCc3cncc(-n4cc([C@H]5CCCO5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5082381 IC50 10.0 nM
CCc1cc(N2CCNCC2)c2ccc(OCc3cncc(-n4cc([C@H]5CCCO5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5080339 IC50 10.0 nM
CCc1cc(NCCOC)c2ncc(OCc3cncc(-n4cc([C@H]5CCCO5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5076079 IC50 10.0 nM
CCNc1ccc2ccc(CCc3cncc(-n4cc([C@@H]5CCCO5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5092318 IC50 10.0 nM
CCc1cc(NCCN(C)C)c2ccc(CCc3cncc(-n4cc([C@@H]5CCCO5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5093618 IC50 10.0 nM
Nc1ncnc2c1c([C@H]1CCCO1)cn2-c1cncc(COc2ccc3ccc(N4CCC4)nc3c2)n1 CHEMBL5072766 IC50 10.0 nM
CCc1cc(NCCOC)c2c(F)cc(OCc3cncc(-n4cc([C@H]5CCCO5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5086859 IC50 10.0 nM
CCc1cc(NCCOC)c2c(F)cc(OCc3cncc(-n4cc([C@@H]5CCCO5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5090516 IC50 10.0 nM
CCc1cc(NC(C)=O)c2ccc(OCc3cncc(-n4cc([C@@H]5CCCO5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5084980 IC50 10.0 nM
CCc1cc(C)c2ccc(OCc3cncc(-n4cc([C@@H]5CCCO5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5093687 IC50 10.0 nM
CCc1cc(N(C)C2CC2)c2ccc(OCc3cncc(-n4cc([C@@H]5CCCO5)c5c(N)ncnc54)n3)cc2n1 CHEMBL5080232 IC50 10.0 nM
CCc1ccc2ccc(OCc3cncc(-n4cc(-c5ccn(C)n5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5079428 IC50 10.0 nM
CS(=O)(=O)c1cn(-c2cncc(COc3ccc4ccc(N5CCC5)nc4c3)c2)c2ncnc(N)c12 CHEMBL5094343 IC50 10.0 nM
Cn1ccc(-c2cn(-c3cncc(COc4ccc5ccc(N6CCOCC6)nc5c4)c3)c3ncnc(N)c23)n1 CHEMBL5078635 IC50 10.0 nM
CC(=O)NC1CN(c2ccc3ccc(OCc4cncc(-n5cc(-c6ccn(C)n6)c6c(N)ncnc65)c4)cc3n2)C1 CHEMBL5074705 IC50 10.0 nM
Cn1ccc(-c2cn(-c3cncc(COc4ccc5ccc(N6CC7(CC7)C6)nc5c4)c3)c3ncnc(N)c23)n1 CHEMBL5073348 IC50 10.0 nM
Cn1ccc(-c2cn(-c3cncc(COc4cc(F)c5ccc(N6CCC6)nc5c4)c3)c3ncnc(N)c23)n1 CHEMBL5079618 IC50 10.0 nM
CNc1ccc2ccc(OCc3cccc(-n4ccc5c(N)ncnc54)c3F)cc2n1 CHEMBL5082845 IC50 10.0 nM
CCc1cc(N(C)C)c2ccc(OCc3cncc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5093847 IC50 10.0 nM
Nc1ccc2ccc(OCc3cncc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5076424 IC50 10.0 nM
O=C(NCc1cn2cc(CNCC3(O)CCCCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5434265 IC50 10.0 nM
Nc1ncnc2c1c(-n1cccn1)cn2[C@@H]1C[C@H](C(=O)Nc2ccc3ccc(N4CCC4)nc3c2)[C@@H](O)C1 CHEMBL5432817 IC50 10.0 nM
CN(C(=O)[C@H]1O[C@@H](n2cc(-n3cccn3)c3c(N)ncnc32)C[C@@H]1O)c1ccc2ccc(N3CCC3)nc2c1 CHEMBL5432662 IC50 10.0 nM
Nc1ccnc(NC(=O)[C@H]2O[C@@H](n3cc(-n4cccn4)c4c(N)ncnc43)C[C@@H]2O)c1 CHEMBL5405126 IC50 10.0 nM
Nc1ncnc2c1ccn2[C@@H]1O[C@H](C(=O)Nc2ccc3ccc(N4CCC4)nc3c2)[C@@H](O)[C@@H]1F CHEMBL5415408 IC50 10.0 nM
N#Cc1cn([C@@H]2O[C@H](C(=O)Nc3ccc4ccc(N5CCC5)nc4c3)[C@@H](O)[C@H]2O)c2ncnc(N)c12 CHEMBL5394334 IC50 10.0 nM
COc1ccc(NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)cc1Cl CHEMBL5404255 IC50 10.0 nM
Cc1nc2cc(NC(=O)[C@H]3O[C@@H](n4cc(-c5ccn(C)n5)c5c(N)ncnc54)[C@H](O)[C@@H]3O)ccc2o1 CHEMBL5440822 IC50 10.0 nM
CN1CCC(N(CCCN)C(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CC1 CHEMBL5424685 IC50 10.0 nM
CN1CCC(N(C(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)C2CC2)CC1 CHEMBL5398406 IC50 10.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCc5nc[nH]c5C4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5440493 IC50 10.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCN(Cc5ccccc5)CC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5399886 IC50 10.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCN(CC5CCC5)CC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5428868 IC50 10.0 nM
c1cc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)cn2)c2cn[nH]c2c1 CHEMBL5395715 IC50 10.1 nM
COc1ccc2[nH]ncc2c1-c1cn(Cc2cn3cc(CNCC4(O)CCC4)ccc3n2)nn1 CHEMBL5395177 IC50 10.6 nM
CC1(CNCc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)CCC1 CHEMBL5413677 IC50 10.6 nM
O=C(NCc1cn2cc(CNCC3CC(F)(F)C3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5408373 IC50 10.64 nM
CC(C)(C)CNCc1ccc2nc(Cn3cc(-c4cccc5[nH]ncc45)nn3)cn2c1 CHEMBL5408233 IC50 11.34 nM
OC1(CNCc2ccc3nc(Cn4cc(-c5ccc(F)c6[nH]ncc56)nn4)cn3c2)CCC1 CHEMBL5428157 IC50 11.4 nM
O=C(NCc1cn2cc(CNCC3(O)CCCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5415384 IC50 11.53 nM
CC1(C)CCN(Cc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)CC1 CHEMBL5401392 IC50 12.4 nM
c1cc(-c2cn(Cc3cn4cc(CNCC5CCCCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5437195 IC50 12.7 nM
Nc1ncnc2c1c(Br)cn2[C@H]1C[C@H](O)[C@@H](/C=C/CCCNCC23CC(F)(C2)C3)O1 CHEMBL5418391 IC50 12.75 nM
CC[C@H](C)CNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5397826 IC50 12.77 nM
CC(C)(C)CCNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5413504 IC50 13.0 nM
O=C(NCc1cn2cc(CNC3CC34CCC4)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5395718 IC50 13.14 nM
CC(C)(C)CNCc1ccc2nc(Cn3cc(-c4cc(C5CC5)cc5[nH]ncc45)nn3)cn2c1 CHEMBL5429924 IC50 13.2 nM
O=C(NCc1cn2cc(CNCCC3CC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5432786 IC50 13.7 nM
O=C(NCc1cn2cc(CNCC3(O)CCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5401346 IC50 13.89 nM
c1cc2[nH]ncc2c(-c2cn(Cc3cn4cc(CNCC5CCCCC5)ccc4n3)nn2)n1 CHEMBL5420711 IC50 14.49 nM
CC1(C)CCCN(Cc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)C1 CHEMBL5423571 IC50 14.5 nM
O=C(NCc1cn2cc(CN3CCC4(CC3)CC4)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5436605 IC50 14.9 nM
CC1(CNCc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)CCCCC1 CHEMBL5436314 IC50 15.0 nM
CCC(C)CNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5424174 IC50 15.01 nM
O=C(NCc1cn2cc(CNCC3(F)CCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5397626 IC50 15.6 nM
O=C(NCc1cn2cc(CNCC3CCC3F)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5407938 IC50 15.8 nM
O=C(NCc1cn2cc(CNCc3ccccc3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5428740 IC50 16.0 nM
CC(C)CNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5414320 IC50 16.3 nM
FC1(F)CC(CNCc2ccc3nc(Cc4cn(-c5cccc6[nH]ncc56)nn4)cn3c2)C1 CHEMBL5436069 IC50 16.3 nM
CC(C)(C)CNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5421904 IC50 16.42 nM
O=C(NCc1cn2cc(CNCc3ccc(F)cc3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5416203 IC50 16.5 nM
CC1(CNCc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)CC1 CHEMBL5430112 IC50 16.8 nM
CC1(C)CCN(Cc2ccc(C(=O)NC[C@]3(O)CCCN(c4cc(NCc5ccccc5)ncn4)C3)c(O)c2)CC1 CHEMBL5279050 IC50 17.0 nM
CC1CCN(Cc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)CC1 CHEMBL5421639 IC50 17.8 nM
CC1CC(CNCc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)C1 CHEMBL5423047 IC50 17.98 nM
O=C(NCc1cn2cc(CNCC3CCC(F)(F)CC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5395770 IC50 18.1 nM
O=C(NCc1cn2cc(CNC(C3CC3)C3CC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5401134 IC50 18.3 nM
O=c1cc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)nc2ccccn12 CHEMBL5419514 IC50 18.4 nM
O=C(NCc1cn2cc(CNCC3CC34CC4)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5404713 IC50 18.7 nM
c1cc2nc(Cn3cc(-c4cc(N5CCOCC5)cc5[nH]ncc45)nn3)cn2cc1CNCC1CCC1 CHEMBL5441023 IC50 19.0 nM
O=C(NCc1cn2cc(CNCC3CCC(F)(F)C3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5435405 IC50 19.3 nM
O=C(NCc1cn2cc(CNCCC3CCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5418888 IC50 19.3 nM
Clc1ccc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)c2cn[nH]c12 CHEMBL5411548 IC50 19.3 nM
CC1(C)CC1CNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5432281 IC50 19.5 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/CCCNCC23CC(F)(C2)C3)[C@H](F)[C@H]1O CHEMBL5398180 IC50 19.7 nM
CCC(C)(C)CNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5410826 IC50 19.96 nM
O=C(NCc1cn2cc(CNCC3CCCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5398729 IC50 20.3 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/CCCNCC2CC(F)(F)C2)[C@@H](O)[C@H]1O CHEMBL5398129 IC50 22.7 nM
O=C(NCc1cn2cc(CNC3CCCCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5404037 IC50 23.1 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/CCCN2CCC3(CCC3)C2)[C@@H](O)[C@H]1O CHEMBL5432153 IC50 23.94 nM
CC1(C)CCN(Cc2ccc(N3CC(=O)NC4(CCN(c5nc(Cl)nc6[nH]ccc56)CC4)C3)cc2)CC1 CHEMBL5076974 IC50 24.0 nM
O=C(NCc1cn2cc(CN3CC4CCC3CC4)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5440888 IC50 24.1 nM
O=C(NCc1cn2cc(CNCC3CCOC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5405512 IC50 24.7 nM
CC1(NCc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)CCCCC1 CHEMBL5411303 IC50 25.1 nM
O=C(NCc1cn2cc(CNCCC(F)(F)F)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5435148 IC50 25.5 nM
CC(NCC1CCCCC1)c1ccc2nc(Cn3cc(-c4cccc5[nH]ncc45)nn3)cn2c1 CHEMBL5424452 IC50 25.8 nM
CC1(C)CCN(Cc2ccc(N3CC(=O)NC4(CCN(c5cc(NCc6ccccc6)ncn5)CC4)C3)cc2)CC1 CHEMBL5087497 IC50 26.0 nM
O=C(NCc1cn2cc(CNCCC3CC3)ccc2n1)c1cc(=O)c2ccccc2o1 CHEMBL5438352 IC50 26.4 nM
O=C(NCc1cn2cc(CNCC3CC4(CC4)C3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5406054 IC50 27.6 nM
O=C(NCc1cn2cc(CNCCCC(F)(F)F)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5414432 IC50 27.67 nM
COC1(CNCc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)CCC1 CHEMBL5414032 IC50 27.7 nM
CC1(NCc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)CCCC1 CHEMBL5409488 IC50 28.5 nM
O=C(NCc1cn2cc(CCNC3CCCCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5428928 IC50 28.7 nM
CCCCNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5427048 IC50 29.3 nM
O=C(NCc1cn2cc(CNCC3CCCCC3)ccc2n1)c1cc(=O)c2ccccc2o1 CHEMBL5401227 IC50 29.4 nM
CC1(C)CCOC1CNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5410276 IC50 29.9 nM
C[C@H](NCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1)c1ccccc1 CHEMBL5440768 IC50 30.0 nM
O=C(NCc1cn2cc(CN3CCC(C(F)(F)F)CC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5410701 IC50 31.4 nM
CNc1cc(N2CCC3(CC2)CN(c2ccc(CN4CCC(C)(C)CC4)c(F)c2)CC(=O)N3)ncn1 CHEMBL5078591 IC50 32.0 nM
CC(NCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1)C1CCCCC1 CHEMBL5402343 IC50 32.0 nM
CC(C)(C)C(C)(C)NCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5410566 IC50 32.4 nM
O=C(NCc1cn2cc(CNCC3CCC3)ccc2n1)c1cccc2[nH]ncc12 CHEMBL5405346 IC50 32.5 nM
CC1CCCN(Cc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)C1 CHEMBL5427314 IC50 32.6 nM
CC1(CNCc2ccc3nc(CNC(=O)c4cc(=O)c5ccccc5o4)cn3c2)CCCCC1 CHEMBL5433116 IC50 33.9 nM
O=C(NCc1cn2cc(CNCC3CC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5432666 IC50 36.5 nM
CC1(C)CCN(Cc2ccc(N3CC(=O)NC4(CCN(c5cc(NCc6ccccc6)ncn5)CC4)C3)cn2)CC1 CHEMBL5082067 IC50 37.0 nM
O=C(NCc1cn2cc(C(Cc3ccccc3)NCC3CCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5396833 IC50 37.6 nM
CC1(F)CCN(Cc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)CC1 CHEMBL5415984 IC50 37.9 nM
CNc1cc(N2CCC3(CC2)CN(c2ccc(CN4CCC(C)(C)CC4)cc2F)CC(=O)N3)ncn1 CHEMBL5092743 IC50 38.0 nM
O=C(NCc1cn2cc(CNCCc3ccccc3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5417097 IC50 38.0 nM
OC1(CNCc2ccc3nc(Cn4cc(-c5ccc(Cl)c6[nH]ncc56)nn4)cn3c2)CCC1 CHEMBL5403354 IC50 38.4 nM
CCCNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5412014 IC50 40.21 nM
O=C(NCc1cn2cc(CNCCC3CC(F)(F)C3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5403627 IC50 41.8 nM
NC(=O)c1cc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5406610 IC50 42.1 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/CCCNCC2CCC2)[C@@H](O)[C@H]1O CHEMBL5414821 IC50 42.6 nM
O=C(NCc1cn2cc(CNCC3CC3(F)F)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5440120 IC50 42.9 nM
O=C(NCc1cn2cc(CNC3CCC(F)(F)CC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5410188 IC50 43.5 nM
O=C(NCc1cn2cc(CNCC3CCCCC3)ccc2n1)c1cc(Br)cc2[nH]ncc12 CHEMBL5427580 IC50 44.1 nM
O=C(NCc1cn2cc(CNCC3(F)CCCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5410430 IC50 44.1 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/CCCNCc2ccccc2)[C@@H](O)[C@H]1O CHEMBL5431584 IC50 44.8 nM
O=C(NCc1cn2cc(CNC3(C4CCCCC4)CC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5410926 IC50 45.6 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1C[C@H](c2ccc(CCNCC34CC(F)(C3)C4)cc2)[C@@H](O)[C@H]1O CHEMBL5426048 IC50 46.6 nM
O=C(NCc1cn2cc(CNCc3ccccc3)ccc2n1)c1cc(=O)c2ccccc2o1 CHEMBL5413918 IC50 46.7 nM
C[C@@H](NCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1)c1ccccc1 CHEMBL5423790 IC50 48.1 nM
O=C(NCc1cn2cc(CNCC3C4CC3C4C(F)(F)F)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5397305 IC50 48.5 nM
O=C(NCc1cn2cc(CN3CCCC(C(F)(F)F)C3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5435825 IC50 48.8 nM
CC(C)(C)CNCc1ccc2nc(CNC(=O)c3cc(=O)c4ccccc4o3)cn2c1 CHEMBL5440732 IC50 50.6 nM
CC1(C)CCN(Cc2ccc3nc(CNC(=O)c4cc(OCCOCCN)cc5[nH]ncc45)cn3c2)CC1 CHEMBL5395444 IC50 52.1 nM
C[C@H](NCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1)C(C)(C)C CHEMBL5435558 IC50 54.3 nM
O=C(NCc1cn2cc(CNCC3CCCCC3)ccc2n1)c1cc(Cl)cc2[nH]ncc12 CHEMBL5400094 IC50 56.1 nM
O=C(NCc1cn2cc(CN3CC4CCC3C4)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5417019 IC50 56.2 nM
O=C(NCc1cn2cc(CNCC3(F)CCCCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5435890 IC50 57.6 nM
O=C(NCc1cn2cc(CN3CCC(F)CC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5410993 IC50 59.7 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/CCCNCC23CC(F)(C2)C3)[C@@H](O)[C@H]1F CHEMBL5434163 IC50 60.0 nM
CC1(C)CCN(Cc2ccc(N3CC(=O)NC4(CCN(c5ncnc6[nH]ccc56)CC4)C3)cc2)CC1 CHEMBL5084119 IC50 61.0 nM
CC(C)(F)CNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5437727 IC50 61.1 nM
CN(CCC1CC1)Cc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5397622 IC50 61.5 nM
O=C(NCc1cn2cc(CN3CCC(Oc4ccccc4)CC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5399063 IC50 61.7 nM
CC1(C)CC(CNCc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)C1 CHEMBL5397431 IC50 62.2 nM
O=C(NCc1cn2cc(CNCc3cccc(F)c3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5421229 IC50 62.5 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/CCCN2CCC(F)(F)CC2)[C@@H](O)[C@H]1O CHEMBL5425735 IC50 63.5 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1C[C@H](c2ccc(CN3CCC4(CCC4)C3)cc2)[C@@H](O)[C@H]1O CHEMBL5432111 IC50 63.7 nM
c1cc(-c2ncn(Cc3cn4cc(CNCC5CCC5)ccc4n3)n2)c2cn[nH]c2c1 CHEMBL5412665 IC50 64.4 nM
O=C(NCc1cn2cc(CNCc3ccc(O)cc3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5415975 IC50 64.9 nM
O=C(NCc1cn2cc(CN3CCCCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5428084 IC50 69.07 nM
CC(C)(O)CNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5420506 IC50 69.5 nM
O=C(NCc1cn2cc(CNCC3CCCO3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5399704 IC50 74.4 nM
O=C(NCc1cn2cc(CNCC3CC4(CCC4)C3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5431180 IC50 76.3 nM
OC1(CNCc2ccc3nc(Cn4cc(-c5nccc6[nH]ncc56)nn4)cn3c2)CCC1 CHEMBL5413505 IC50 76.6 nM
O=C(NCc1cn2cc(CNCC3CCCOC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5440513 IC50 79.2 nM
O=C(NCc1cn2cc(CNC3CCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5431771 IC50 79.8 nM
O=C(NCc1cn2cc(CNCCC3CCCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5434239 IC50 80.1 nM
O=C(NCc1cn2cc([C@H]3COC[C@@H](C4CCCCC4)N3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5422954 IC50 81.26 nM
O=C(NCc1cn2cc(CNC[C@@H]3CCCO3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5430664 IC50 83.7 nM
CC1(C)CCN(Cc2ccc(N3CC(=O)NC4(CCN(c5cc(NC6CC6)ncn5)CC4)C3)cc2)CC1 CHEMBL5092187 IC50 84.0 nM
O=C(NCc1cn2cc(CNCc3ccccc3F)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5419786 IC50 84.0 nM
O=C(NCc1cn2cc(CN3CCC(F)(F)CC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5398318 IC50 84.3 nM
O=C(NCc1cn2cc(CNC3(C4CC4)CC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5438421 IC50 84.8 nM
O=C(NCc1cn2cc(CNCCCc3ccccc3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5426480 IC50 87.0 nM
O=C(NCc1cn2cc(CNC[C@H]3CCCO3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5401052 IC50 87.2 nM
O=C(NCc1cn2cc(CN3CCc4ccccc4C3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5418402 IC50 87.7 nM
CNc1cc(N2CCC3(CC2)CN(c2ccc(CN4CCC(C)(C)CC4)cc2)CC(=O)N3)ncn1 CHEMBL5084812 IC50 89.0 nM
CC1(CNCc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)CCCO1 CHEMBL5405252 IC50 93.2 nM
COC(C)(C)CNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5414504 IC50 98.7 nM
CN(Cc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1)CC1CC1 CHEMBL5398066 IC50 99.0 nM
CC(C)(C)C1CCN(Cc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)CC1 CHEMBL5426557 IC50 99.1 nM
Nc1ccnc2cc(OC[C@H]3O[C@@H](n4cc(Br)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)ccc12 CHEMBL5075448 IC50 100.0 nM
Cc1cc(N)c2ccc(OC[C@H]3O[C@@H](n4cc(Br)c5c(N)ncnc54)C[C@@H]3O)cc2n1 CHEMBL5079221 IC50 100.0 nM
Nc1nc2ccc(OC[C@H]3O[C@@H](n4cc(Br)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2[nH]1 CHEMBL5091551 IC50 100.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(Br)c5c(N)nc(N)nc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5089789 IC50 100.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(Br)c5c(N)nccc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5090186 IC50 100.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(-c5cc(F)cc(F)c5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5084670 IC50 100.0 nM
Nc1ccc2ccc(CC[C@H]3C[C@@H](n4cc([C@H]5CCOC5)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5087195 IC50 100.0 nM
Nc1ccc2ccc(CC[C@H]3C[C@@H](n4cc([C@@H]5CCOC5)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5089627 IC50 100.0 nM
CCCc1cn([C@@H]2C[C@H](CCc3ccc4ccc(N)nc4c3)[C@@H](O)[C@H]2O)c2ncnc(N)c12 CHEMBL5078272 IC50 100.0 nM
Cn1cc(-c2cn([C@@H]3C[C@H](CCc4ccc5ccc(N)nc5c4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)cn1 CHEMBL5094644 IC50 100.0 nM
CNc1ccc2cc(CC[C@H]3C[C@@H](n4cc(C)c5c(N)ncnc54)[C@H](O)[C@@H]3O)ccc2n1 CHEMBL5076559 IC50 100.0 nM
Nc1ncnc2c1ccn2[C@@H]1C[C@H](COc2ccc3ccc(N4CCCC4)nc3c2)[C@@H](O)[C@H]1O CHEMBL5075451 IC50 100.0 nM
Nc1ncnc2c1ccn2[C@@H]1C[C@H](CCc2ccc3ccc(N4CCCC4)nc3c2)[C@@H](O)[C@H]1O CHEMBL5076519 IC50 100.0 nM
Nc1ncnc2c1ccn2[C@@H]1C[C@H](CCc2ccc3ccc(NCCO)nc3c2)[C@@H](O)[C@H]1O CHEMBL5082271 IC50 100.0 nM
CNc1ccc2cc(CC[C@H]3C[C@@H](n4ccc5c(N)ncnc54)[C@H](O)[C@@H]3O)ccc2n1 CHEMBL5090146 IC50 100.0 nM
Nc1ncnc2c1ccn2[C@@H]1C[C@H](CCc2ccc3ccc(NCc4ccccc4)nc3c2)[C@@H](O)[C@H]1O CHEMBL5081606 IC50 100.0 nM
Nc1ccc2ccc(OC[C@H]3C[C@@H](n4ccc5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5076685 IC50 100.0 nM
Nc1ccc2cc(CC[C@H]3C[C@@H](n4ccc5c(N)ncnc54)[C@H](O)[C@@H]3O)ccc2n1 CHEMBL5073243 IC50 100.0 nM
Nc1ccc2ccc(CC[C@H]3C[C@@H](n4ccc5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL4541714 IC50 100.0 nM
Nc1ccc2ccc(OC[C@H]3O[C@@H](n4ccc5c(NCCc6ccccc6)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5080760 IC50 100.0 nM
CNc1ccc2ccc(OC[C@@H]3C[C@@H](O)[C@H](n4cc(C5CCCC5)c5c(N)ncnc54)O3)cc2n1 CHEMBL5078283 IC50 100.0 nM
CN(CCS(C)(=O)=O)c1ccc2ccc(OC[C@H]3O[C@@H](n4cc(-c5ccn(C)n5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5085789 IC50 100.0 nM
CCc1nc2cc(OC[C@H]3O[C@@H](n4cc(-c5ccn(C)n5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)ccc2[nH]1 CHEMBL5077383 IC50 100.0 nM
CNc1nc2cc(OC[C@H]3O[C@@H](n4cc(-c5ccn(C)n5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)ccc2o1 CHEMBL5084517 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](COc4ccc(C(=O)N5CCNCC5)c(N)c4)[C@@H](O)[C@@H]3F)c3ncnc(N)c23)n1 CHEMBL5094481 IC50 100.0 nM
CNc1nc2cc(OC[C@H]3O[C@@H](n4cc(-c5ccn(C)n5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)ccc2s1 CHEMBL5075003 IC50 100.0 nM
Nc1ncnc2c1ccn2[C@H]1C[C@H](O)[C@@H](COc2ccc3ccc(N4CC(N)C4)nc3c2)O1 CHEMBL5086963 IC50 100.0 nM
Nc1ncnc2c1ccn2[C@@H]1O[C@H](CCC2CCNCC2)[C@@H](O)[C@@H]1F CHEMBL5077180 IC50 100.0 nM
CNc1nc2cc(CC[C@H]3O[C@@H](n4cc(-n5cccn5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)ccc2s1 CHEMBL5076932 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](COc4ccc5ccc(NC6CNC6)nc5c4)[C@@H](O)[C@@H]3F)c3ncnc(N)c23)n1 CHEMBL5078254 IC50 100.0 nM
Nc1ncnc2c1ccn2[C@@H]1O[C@H](COc2ccc3cnc(N[C@H]4C[C@@H](N)C4)nc3c2)[C@@H](O)[C@@H]1F CHEMBL5089822 IC50 100.0 nM
Nc1ncnc2c1c(-n1cccn1)cn2C1CC(COc2ccc3ccc(NC4CCC4)nc3c2)C(O)C1F CHEMBL5079955 IC50 100.0 nM
CNc1ccc2ccc(OCc3cc(C(N)=O)cc(-n4cc(Cl)c5c(N)ncnc54)c3)cc2n1 CHEMBL5070853 IC50 100.0 nM
CNc1ccc2ccc(OCc3cccc(-n4cc(CCN(C)C)c5c(N)ncnc54)c3)cc2n1 CHEMBL5085101 IC50 100.0 nM
CNc1ccc2ccc(OCc3cncc(-n4cc(C5CCN(C)CC5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5077576 IC50 100.0 nM
Cc1cc(N)c2ccc(OCc3cncc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5078051 IC50 100.0 nM
Nc1ncnc2c1ccn2-c1csc(COc2ccc3ccc(N4CCCC4)nc3c2)n1 CHEMBL5094451 IC50 100.0 nM
Nc1ncnc2c1c(Cl)cn2-c1cncc(COc2ccc3ccc(NCC4CC4)nc3c2)c1 CHEMBL5092719 IC50 100.0 nM
CNc1ccc2ccc(OCc3cncc(-n4ccc5c(N)nc(N)nc54)c3)cc2n1 CHEMBL5087964 IC50 100.0 nM
CNc1ccc2ccc(OCc3cncc(-n4cc(C5CCCC5)c5cncnc54)c3)cc2n1 CHEMBL5082007 IC50 100.0 nM
Cc1cc(N)c2ccc(OCc3cccc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5094589 IC50 100.0 nM
Nc1ncnc2c1c(Cl)cn2-c1cccc(COc2ccc3ccc(NCC4CC4)nc3c2)c1 CHEMBL5089569 IC50 100.0 nM
CNc1ccc2cc(CCc3cccc(-n4cc(Cl)c5c(N)ncnc54)c3)ccc2n1 CHEMBL5089836 IC50 100.0 nM
CNc1ccc2ccc(CNc3cccc(-n4cc(Br)c5c(N)ncnc54)c3)cc2n1 CHEMBL5082728 IC50 100.0 nM
CNc1ccc2ccc(OCc3cc(Br)cc(-n4cc(Cl)c5c(N)ncnc54)c3)cc2n1 CHEMBL5089090 IC50 100.0 nM
CNc1ccc2ccc(OCc3cc(OC)cc(-n4cc(Cl)c5c(N)ncnc54)c3)cc2n1 CHEMBL5084904 IC50 100.0 nM
CNc1ccc2ccc(OCc3ccnc(-n4cc(Cl)c5c(N)ncnc54)c3)cc2n1 CHEMBL5082050 IC50 100.0 nM
CCc1cc(=O)c2ccc(OCc3cncc(-n4cc(C5CCCC5)c5c(N)ncnc54)c3)cc2[nH]1 CHEMBL5078344 IC50 100.0 nM
CNc1ccc2ccc(OCc3cc(C#N)cc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5084442 IC50 100.0 nM
Nc1cc(OCc2cncc(-n3cc([C@@H]4CCCO4)c4c(N)ncnc43)c2)ccc1C(=O)N1CCNCC1 CHEMBL5090880 IC50 100.0 nM
C[S+]([O-])c1cn(-c2cncc(COc3ccc4ccc(N5CCC5)nc4c3)c2)c2ncnc(N)c12 CHEMBL5094519 IC50 100.0 nM
CN(CCS(C)(=O)=O)c1ccc2ccc(OCc3cncc(-n4cc(-c5ccn(C)n5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5075151 IC50 100.0 nM
Cn1ccc(-c2cn(-c3cncc(COc4ccc(C(=O)N5CCNCC5)c(N)c4)c3)c3ncnc(N)c23)n1 CHEMBL5086418 IC50 100.0 nM
Cn1ccc(-c2cn(-c3cncc(COc4ccc(C(=O)NC5CCOCC5)c(N)c4)c3)c3ncnc(N)c23)n1 CHEMBL5083672 IC50 100.0 nM
Cn1ccc(-c2cn(-c3cncc(COc4ccc5ccc(C6CCOCC6)nc5c4)c3)c3ncnc(N)c23)n1 CHEMBL5088869 IC50 100.0 nM
Cn1ccc(-c2cn(-c3cncc(COc4ccc5ccc(N6CC7(CCC7)C6)nc5c4)c3)c3ncnc(N)c23)n1 CHEMBL5081192 IC50 100.0 nM
Cn1ccc(-c2cn(-c3cncc(COc4ccc5ccc(N6CCC(F)(F)CC6)nc5c4)c3)c3ncnc(N)c23)n1 CHEMBL5080745 IC50 100.0 nM
Cn1ccc(-c2cn(-c3cncc(COc4ccc(CN5CCC(CO)CC5)c(N)c4)c3)c3ncnc(N)c23)n1 CHEMBL5092283 IC50 100.0 nM
Cn1ccc(-c2cn(-c3cncc(COc4ccc5ccc(N6CC7(COC7)C6)nc5c4)c3)c3ncnc(N)c23)n1 CHEMBL5074946 IC50 100.0 nM
CN1CCN(c2ccc3ccc(OCc4cncc(-n5cc(-c6ccn(C)n6)c6c(N)ncnc65)c4)cc3n2)CC1 CHEMBL5090156 IC50 100.0 nM
Cn1ccc(-c2cn(-c3cncc(COc4ccc5ccc(N6CC(CO)(CO)C6)nc5c4)c3)c3ncnc(N)c23)n1 CHEMBL5076541 IC50 100.0 nM
Cn1ccc(-c2cn(-c3cncc(COc4ccc(CN5CCOCC5)c(N)c4)c3)c3ncnc(N)c23)n1 CHEMBL5091454 IC50 100.0 nM
CC(C)(C)[C@@H]1COC[C@H](c2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)N1 CHEMBL5431533 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCC4CCNCC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5419266 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)N(CCCO)C4CCNCC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5417957 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)N(CC[C@H](N)C(=O)O)C4CCNCC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5426882 IC50 100.0 nM
COCCN(C(=O)[C@H]1O[C@@H](n2cc(-c3ccn(C)n3)c3c(N)ncnc32)[C@H](O)[C@@H]1O)c1ccc2ccc(N3CCC3)nc2c1 CHEMBL5400806 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCC4CCN(CCO)CC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5393873 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCc4cnccn4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5438384 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCC4CCOCC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5427140 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCC4CCC(F)(F)CC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5436588 IC50 100.0 nM
CN1CCC(CNC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CC1 CHEMBL5417315 IC50 100.0 nM
CN1CCC(NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CC1 CHEMBL5395869 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCc4ccccc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5409478 IC50 100.0 nM
CCNc1ccnc(NC(=O)[C@H]2O[C@@H](n3cc(-n4cccn4)c4c(N)ncnc43)C[C@@H]2O)c1 CHEMBL5436533 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)N(CC[C@H](N)C(=O)O)c4ccc5nc(N)[nH]c5c4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5436002 IC50 100.0 nM
COc1cccc(CNC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)c1 CHEMBL5406062 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCC[C@H](N)C(=O)O)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5395780 IC50 100.0 nM
CN1CCC(NC(=O)[C@H]2C[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CC1 CHEMBL5416195 IC50 100.0 nM
CN1CCC(N(CCCNC(=O)OCc2ccccc2)C(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CC1 CHEMBL5435197 IC50 100.0 nM
CN(C)CCCN(C(=O)[C@H]1O[C@@H](n2cc(-c3ccn(C)n3)c3c(N)ncnc32)[C@H](O)[C@@H]1O)C1CCN(C)CC1 CHEMBL5422355 IC50 100.0 nM
CN1CCC(NC(=O)[C@H]2O[C@@H](n3cc(C4CCCO4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CC1 CHEMBL5424964 IC50 100.0 nM
CN1CCC(NC(=O)[C@H]2O[C@@H](n3cc(C4CCCC4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CC1 CHEMBL5423008 IC50 100.0 nM
COCCn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCN(C)CC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5413284 IC50 100.0 nM
C#CCCCN(C(=O)[C@H]1O[C@@H](n2cc(-c3ccn(C)n3)c3c(N)ncnc32)[C@H](O)[C@@H]1O)C1CCN(C)CC1 CHEMBL5428105 IC50 100.0 nM
CN1CCC(NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@@H](F)[C@@H]2O)CC1 CHEMBL5433990 IC50 100.0 nM
CNc1ccc2ccc(NC(=O)[C@H]3O[C@@H](n4ccc5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5394597 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4ccc5nsnc5c4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5414990 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCN(S(C)(=O)=O)CC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5421926 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCCC4CCOCC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5399145 IC50 100.0 nM
COc1ccccc1CNC(=O)[C@H]1O[C@@H](n2cc(-c3ccn(C)n3)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL5395895 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4ccc(-c5ccccc5)cc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5411550 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)N4CCc5ccccc54)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5438998 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4ccc(Oc5ccccc5)cc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5419954 IC50 100.0 nM
CC(CNC(=O)[C@H]1O[C@@H](n2cc(-c3ccn(C)n3)c3c(N)ncnc32)[C@H](O)[C@@H]1O)c1ccccc1 CHEMBL5395117 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCCCn4ccnc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5440579 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCC(O)CC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5425187 IC50 100.0 nM
Cn1cc(NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)cn1 CHEMBL5398454 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4cccc(C#N)c4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5430287 IC50 100.0 nM
Cc1cc(CNC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)no1 CHEMBL5417960 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4ccc(S(=O)(=O)N5CCOCC5)cc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5429685 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCCc4ccc(C(F)(F)F)cc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5425867 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4ccnn4C)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5400960 IC50 100.0 nM
CCCCc1ccc(NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)cc1 CHEMBL5422632 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCCc4ccc(Cl)cc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5412987 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCCc4ccncc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5433488 IC50 100.0 nM
Cc1cc(C#N)ccc1NC(=O)[C@H]1O[C@@H](n2cc(-c3ccn(C)n3)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL5397971 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4ccc5ccccc5c4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5396557 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC(Cc4ccccc4)c4ccccc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5415119 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCCc4ccc(-c5ccccc5)cc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5409047 IC50 100.0 nM
Cc1cc(F)ccc1NC(=O)[C@H]1O[C@@H](n2cc(-c3ccn(C)n3)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL5406224 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4cccc5nsnc45)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5415038 IC50 100.0 nM
COc1ccccc1[C@H](C)NC(=O)[C@H]1O[C@@H](n2cc(-c3ccn(C)n3)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL5424081 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCCC4CCCCC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5440973 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCc4ccccc4-n4cccn4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5402023 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4ccncc4Cl)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5435262 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4ccc5c(c4)NC(=O)CC5)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5395564 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4ccc5c(c4)OCCCO5)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5428633 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4ccc(CN5CCS(=O)(=O)CC5)cc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5439754 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4Cc5ccccc5C4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5403560 IC50 100.0 nM
CN1CCN(c2ccc(NC(=O)[C@H]3O[C@@H](n4cc(-c5ccn(C)n5)c5c(N)ncnc54)[C@H](O)[C@@H]3O)nc2)CC1 CHEMBL5412180 IC50 100.0 nM
CCC(NC(=O)[C@H]1O[C@@H](n2cc(-c3ccn(C)n3)c3c(N)ncnc32)[C@H](O)[C@@H]1O)c1ccccc1 CHEMBL5427099 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCCCN4CCCC4=O)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5436529 IC50 100.0 nM
CC(=O)Nc1ccccc1NC(=O)[C@H]1O[C@@H](n2cc(-c3ccn(C)n3)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL5396189 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCc4ccc5ccccc5c4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5405715 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4ccc(OC(F)F)cc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5415061 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCCc4ccccc4Cl)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5434457 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCCc4ccc5ccccc5c4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5394467 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4ccc(C(=O)N5CCCCC5)cc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5406038 IC50 100.0 nM
CNC(=O)c1ccc(NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)cc1 CHEMBL5420046 IC50 100.0 nM
CC(CCc1ccccc1)NC(=O)[C@H]1O[C@@H](n2cc(-c3ccn(C)n3)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL5437609 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4ccc(-n5cnnn5)cc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5408424 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4ccc(OCCN5CCOCC5)cc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5411767 IC50 100.0 nM
CNC(=O)Nc1cc(NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)ccn1 CHEMBL5429548 IC50 100.0 nM
CN1CCC(N(CCC#N)C(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CC1 CHEMBL5434209 IC50 100.0 nM
CN1CCC(N(CCCO)C(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CC1 CHEMBL5438231 IC50 100.0 nM
CN1CCC(N(CCCc2cnoc2)C(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CC1 CHEMBL5411268 IC50 100.0 nM
CN1CCC(N(C[C@H]2CCNC2)C(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CC1 CHEMBL5433265 IC50 100.0 nM
CN1CCC(N(CCCC#N)C(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CC1 CHEMBL5399467 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4cccnc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5437458 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)N[C@H]4CCc5nc(N)sc5C4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5439811 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4cc(NC5CCC5)ccn4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5396244 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4cc(NCC5CC5)ccn4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5434433 IC50 100.0 nM
COCCNc1ccnc(NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)c1 CHEMBL5421534 IC50 100.0 nM
CN(C)c1ccnc(NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)c1 CHEMBL5428327 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4ccnc(NC5CCC5)c4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5427650 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4cc(N5CCC5)ccn4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5435344 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4cc(NCC(F)F)ccn4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5407633 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)Nc4ccccc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5425550 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)N4CCNCC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5431357 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCN(CCO)CC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5404306 IC50 100.0 nM
CN1CC[C@@H](NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)C1 CHEMBL5434571 IC50 100.0 nM
CN1[C@@H]2CC[C@H]1C[C@@H](NC(=O)[C@H]1O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]1O)C2 CHEMBL5432434 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCc5cnc(N)nc5C4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5410979 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCNC(C)(C)C4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5400323 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCc4cc(F)cc(F)c4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5421287 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCCc4ccccc4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5395067 IC50 100.0 nM
CNc1cccc(CCNC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)n1 CHEMBL5419234 IC50 100.0 nM
C[C@H](NC(=O)[C@H]1O[C@@H](n2cc(-c3ccn(C)n3)c3c(N)ncnc32)[C@H](O)[C@@H]1O)C1CCNCC1 CHEMBL5432989 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)N[C@@H]4CCc5nc(N)sc5C4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5427543 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCC4(O)CCNCC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5416151 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)N[C@H]4CC[C@](C)(O)CC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5439237 IC50 100.0 nM
CN1CC[C@H](NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)C1 CHEMBL5396892 IC50 100.0 nM
CN1[C@@H]2CC[C@H]1C[C@H](NC(=O)[C@H]1O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]1O)C2 CHEMBL5420458 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCN5CCCC5C4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5429726 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCn5ccnc5C4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5404601 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCC5(CC4)CNC5)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5435078 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)N[C@H]4CC[C@@](C)(O)CC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5404671 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CC5(CNC5)C4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5418012 IC50 100.0 nM
C[C@H]1C[C@H](NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CCN1 CHEMBL5421828 IC50 100.0 nM
C[C@H]1C[C@@H](NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CCN1 CHEMBL5409182 IC50 100.0 nM
CN1CC(NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)C1 CHEMBL5418726 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)N4CCc5[nH]cnc5C4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5417532 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5402913 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)N[C@@H]4CCCNC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5395412 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)N[C@H]4CCCNC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5411124 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCN(c5ccccc5)CC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5436575 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCN(c5ccccn5)CC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5397854 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCN(C5CCC5)CC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5437379 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NC4CCN(C(=O)OCc5ccccc5)CC4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5438930 IC50 100.0 nM
CCNc1cc(CNC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)ccn1 CHEMBL5429946 IC50 100.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](C(=O)NCCc4c[nH]cn4)[C@@H](O)[C@H]3O)c3ncnc(N)c23)n1 CHEMBL5425146 IC50 100.0 nM
C[C@H]1C[C@@H](NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CCN1C CHEMBL5439181 IC50 100.0 nM
C[C@@H]1C[C@H](NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CCN1C CHEMBL5418613 IC50 100.0 nM
C[C@H]1C[C@H](NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CCN1C CHEMBL5436758 IC50 100.0 nM
C[C@@H]1C[C@@H](NC(=O)[C@H]2O[C@@H](n3cc(-c4ccn(C)n4)c4c(N)ncnc43)[C@H](O)[C@@H]2O)CCN1C CHEMBL5437797 IC50 100.0 nM
O=C(NCc1cn2cc(CNC3CC(F)(F)C3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5413313 IC50 102.0 nM
CCC(O)CNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5426346 IC50 103.0 nM
CC1(C)CCN(Cc2ccc([C@H]3C[C@@H](n4cc(Br)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2)CC1 CHEMBL5418993 IC50 103.0 nM
CC(C)(C)OCCNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5411045 IC50 104.0 nM
O=C(NCc1cn2cc(CNCC3COC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5394651 IC50 109.0 nM
O=C(NCc1cn2cc(CNC3CCOC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5416143 IC50 110.0 nM
O=C(NCc1cn2cc(CCNCc3ccccc3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5429792 IC50 111.0 nM
O=C(NCc1cn2cc(CNCc3cccc(C4CC4)c3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5439554 IC50 112.0 nM
CN(C)C(=O)c1cc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5431774 IC50 112.0 nM
O=C(NCc1cn2cc(CNCC3CCCCO3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5410614 IC50 114.0 nM
O=C(NCc1cn2cc(CNC(CO)C3CCCCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5410761 IC50 114.0 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1C[C@H](c2cccc(CCNCC34CC(F)(C3)C4)c2)[C@@H](O)[C@H]1O CHEMBL5414013 IC50 117.0 nM
O=C(NCc1cn2cc(CNC3CCCOC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5396908 IC50 119.0 nM
NC1(CNCc2ccc3nc(Cn4cc(-c5ccc(F)c6[nH]ncc56)nn4)cn3c2)CCCC1 CHEMBL5422186 IC50 120.0 nM
CN(Cc1ccccc1)Cc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5400370 IC50 122.0 nM
O=C1CC(c2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)NC(C2CCCCC2)C1 CHEMBL5405948 IC50 122.0 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](CC/C=C/CNCc2ccccc2)[C@@H](O)[C@H]1O CHEMBL5413769 IC50 123.0 nM
O=C(NCc1cn2cc(CNCCOC(F)(F)F)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5401233 IC50 131.0 nM
CC(NCC1CCCCC1)c1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5412819 IC50 132.0 nM
CC1(C)CCC(CNCc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)O1 CHEMBL5416246 IC50 136.0 nM
O=C(NCc1cn2cc(CNCc3cccnc3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5416346 IC50 143.0 nM
O=C(NCc1cn2cc(CNCCc3cccnc3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5411491 IC50 143.0 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1C[C@H](c2ccc(CNCC3CCC3)cc2)[C@@H](O)[C@H]1O CHEMBL5438640 IC50 150.0 nM
CC(C)(NCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1)c1ccccc1 CHEMBL5406055 IC50 163.0 nM
O=C(NCc1cn2cc(CNCc3ccc(Cl)cc3)ccc2n1)c1cc(=O)c2ccccc2o1 CHEMBL5403336 IC50 168.0 nM
O=C(NCc1cn2cc(CN3CCC(Cc4ccccc4)CC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5430764 IC50 177.0 nM
Cc1ccc2c(=O)cc(C(=O)NCc3cn4cc(CNCC5CCCCC5)ccc4n3)oc2c1 CHEMBL5424572 IC50 179.0 nM
O=C(NCc1cn2cc(CNCC3CCCCC3)ccc2n1)c1cccc2[nH]ncc12 CHEMBL5423433 IC50 179.0 nM
CC1(C)CCN(Cc2ccc3nc(CNC(=O)c4cc(=O)c5c(F)cccc5o4)cn3c2)CC1 CHEMBL5395221 IC50 186.0 nM
O=C(NCc1cn2cc([C@H]3COC[C@@H](C4CCCCC4)N3)ccc2n1)c1cc(=O)c2ccccc2o1 CHEMBL5432990 IC50 195.0 nM
CN(Cc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1)CC(C)(C)C CHEMBL5430264 IC50 197.0 nM
N#CCC(NCC1CCC1)c1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5412073 IC50 202.0 nM
COc1ccc(CNCc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)cc1 CHEMBL5439252 IC50 206.0 nM
O=C(NCc1cn2cc(CN3CCN(c4ccccc4)CC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5428455 IC50 206.0 nM
OCc1ccc2nc(Cn3cc(-c4cc(Br)cc5[nH]ncc45)nn3)cn2c1 CHEMBL5405361 IC50 207.0 nM
O=C(NCc1cn2cc(CNCc3ccccc3)ccc2n1)c1cccc2[nH]ncc12 CHEMBL5418743 IC50 209.0 nM
O=C(NCc1cn2cc(CNCC3CCCCC3)ccc2n1)c1cc(=O)n2c(n1)CCCC2 CHEMBL5393881 IC50 214.0 nM
O=C(NCc1cn2cc(CNC[C@H](O)C(F)(F)F)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5400212 IC50 221.0 nM
CC1(C)COC(CNCc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)C1 CHEMBL5410196 IC50 224.0 nM
CC(C)(C)C1CCC(NCc2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)CC1 CHEMBL5429975 IC50 225.0 nM
O=C(NCC1CCCCC1)c1ccc2nc(Cn3cc(-c4cccc5[nH]ncc45)nn3)cn2c1 CHEMBL5428821 IC50 229.0 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/CCCN2CCC(F)CC2)[C@@H](O)[C@H]1O CHEMBL5426935 IC50 231.0 nM
O=C(NCCO)c1cc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5439913 IC50 233.0 nM
CC(C)(C)[C@H]1COC[C@@H](c2ccc3nc(CNC(=O)c4cc(=O)n5ccccc5n4)cn3c2)N1 CHEMBL5412654 IC50 239.0 nM
O=C(NCc1cn2cc(CNCC3COCCO3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5398661 IC50 241.0 nM
CN(Cc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1)CC1CCCCC1 CHEMBL5398140 IC50 244.0 nM
CC(C)(C)CNCc1ccc2nc(Cn3cc(-c4cncc5[nH]ncc45)nn3)cn2c1 CHEMBL5402292 IC50 246.0 nM
O=C(NCc1cn2cc(CN3CCCCC3)ccc2n1)c1cc(=O)c2ccccc2o1 CHEMBL5420368 IC50 247.0 nM
O=C(NCc1cn2cc(CNCC3CCCCN3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5407232 IC50 260.0 nM
O=C(NCc1cn2cc(CNCCO)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5414922 IC50 267.0 nM
NCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5427358 IC50 272.0 nM
COCCCNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5405802 IC50 276.0 nM
CC1(C)CCN(Cc2ccc(N3CCOC4(CCN(c5cc(NCc6ccccc6)ncn5)CC4)C3)cn2)CC1 CHEMBL5077723 IC50 280.0 nM
O=C(NCc1cn2cc(CNC3C4CC3C4)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5426901 IC50 280.0 nM
O=C(NCc1cn2cc(CNCC3CCCCC3)ccc2n1)c1cc(=O)c2ccc(Cl)cc2o1 CHEMBL5439423 IC50 293.0 nM
C=Cc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5429049 IC50 299.0 nM
NCCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5429466 IC50 299.0 nM
O=C(NCc1cn2cc(CN3CC4CC3CO4)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5403193 IC50 303.0 nM
CC1(C)CCCCN1Cc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5414289 IC50 305.0 nM
O=C(NCc1cn2cc(CNCC3CCCCC3)ccc2n1)c1cc(=O)c2cc(Cl)ccc2o1 CHEMBL5417955 IC50 309.0 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/CCNCc2ccccc2)[C@@H](O)[C@H]1O CHEMBL5425385 IC50 317.0 nM
O=C(NCc1cn2cc(CNCc3cncs3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5434980 IC50 318.0 nM
CC(C)Nc1cc(N2CCC3(CC2)CN(c2ccc(CN4CCC(C)(C)CC4)cc2)CC(=O)N3)ncn1 CHEMBL5083998 IC50 330.0 nM
COC(=O)C(NCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1)C(C)C CHEMBL5417434 IC50 332.0 nM
O=C(NCc1cn2cc(CNCCF)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5433254 IC50 333.0 nM
O=C(NCc1cn2cc(CNC3CC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5431586 IC50 350.0 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/C2CCCNC2)[C@@H](O)[C@H]1O CHEMBL5404960 IC50 351.0 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/CCCN2CCCC(F)C2)[C@@H](O)[C@H]1O CHEMBL5440538 IC50 351.0 nM
O=C(NCc1cn2cc(CNCC3CCOCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5417453 IC50 354.0 nM
O=C(NCc1cn2cc(CN3C4CCC3CC4)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5405250 IC50 391.0 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/C2CCNCC2)[C@@H](O)[C@H]1O CHEMBL5437780 IC50 413.0 nM
CC(C)(C)OC(=O)N1CCCCC1CNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5439761 IC50 429.0 nM
CC(C)(C)NCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5422099 IC50 429.0 nM
CNc1cc(N2CC3(CN(c4ccc(CN5CCC(C)(C)CC5)cc4)CC(=O)N3)C2)ncn1 CHEMBL5094039 IC50 440.0 nM
O=C(NCc1cn2cc(CN3CC(c4ccccn4)C3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5408481 IC50 440.0 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/C2CCNC2)[C@@H](O)[C@H]1O CHEMBL5407539 IC50 453.0 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/C2CNC2)[C@@H](O)[C@H]1O CHEMBL5415391 IC50 460.0 nM
OCc1ccc2nc(Cn3cc(-c4cc(F)cc5[nH]ncc45)nn3)cn2c1 CHEMBL5432197 IC50 462.0 nM
O=C(NCc1cn2cc(CN3CCCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5421721 IC50 480.0 nM
NCCC/C=C/[C@H]1O[C@@H](n2cc(Br)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL5439005 IC50 505.0 nM
O=C(c1cc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)c2cn[nH]c2c1)N1CCOCC1 CHEMBL5408034 IC50 511.0 nM
O=C(NCc1cn2cc(CNCC3CCCNC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5402929 IC50 513.0 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/CC2CNC2)[C@@H](O)[C@H]1O CHEMBL5394824 IC50 522.0 nM
Cc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5423404 IC50 536.0 nM
COc1ccn2cc(CNC(=O)c3cc(=O)n4ccccc4n3)nc2c1 CHEMBL5433377 IC50 543.0 nM
NCC/C=C/[C@H]1O[C@@H](n2cc(Br)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL5397423 IC50 568.0 nM
O=C(NCc1cn2cc(CNCC(F)F)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5435552 IC50 578.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCC[C@H](N)C(=O)O)[C@@H](O)[C@H]1O CHEMBL418052 IC50 590.0 nM
O=C(NCc1cn2cc(CNc3ccc(F)cn3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5398616 IC50 597.0 nM
O=C(NCc1cn2cc(CO)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5433779 IC50 695.0 nM
C=Cc1ccn2cc(CNC(=O)c3cc(=O)n4ccccc4n3)nc2c1 CHEMBL5424111 IC50 700.0 nM
CC(O)c1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5398441 IC50 702.0 nM
O=C(NCc1cn2cc(C3(NCC4CCCCC4)CC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5428847 IC50 735.0 nM
O=C(O)c1cc(-c2cn(Cc3cn4cc(CNCC5CCC5)ccc4n3)nn2)c2cn[nH]c2c1 CHEMBL5424674 IC50 737.0 nM
O=C(NCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1)c1ccccc1 CHEMBL5417503 IC50 742.0 nM
O=C(NCc1cn2cc(CN[C@@H]3C[C@H]3C(F)(F)F)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5437190 IC50 755.0 nM
CC1(C)CCN(Cc2ccc(NCC3(O)CCN(c4cc(NCc5ccccc5)ncn4)CC3)cn2)CC1 CHEMBL5091512 IC50 790.0 nM
O=C(NCc1cn2cc(CNC(=O)C3CCCCC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5430043 IC50 850.0 nM
O=C(NCc1cn2cc(CNCC3CCCCC3)ccc2n1)c1cc(=O)c2ccc(F)cc2o1 CHEMBL5410077 IC50 889.0 nM
Nc1ccc(C(=O)NCc2cn3cc(CNCC4CCCCC4)ccc3n2)cn1 CHEMBL5405286 IC50 909.0 nM
CCN(CC)Cc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5431854 IC50 917.0 nM
O=C(NCc1cn2cc(C3CC3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5424075 IC50 939.0 nM
O=C(NCc1cn2cc(C(O)c3ccccc3)ccc2n1)c1cc(=O)n2ccccc2n1 CHEMBL5394396 IC50 945.0 nM
CS(=O)(=O)CCNCc1ccc2nc(CNC(=O)c3cc(=O)n4ccccc4n3)cn2c1 CHEMBL5435462 IC50 947.0 nM
CN(C)c1cc(N2CCC3(CC2)CN(c2ccc(CN4CCC(C)(C)CC4)cc2)CC(=O)N3)ncn1 CHEMBL5076504 IC50 970.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(C5CCCCC5)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5091528 IC50 1000.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4ccc5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5089969 IC50 1000.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(-c5ccccn5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5076876 IC50 1000.0 nM
CCNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(-c5cn(C)cn5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5094610 IC50 1000.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(CC5CCCC5)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5073707 IC50 1000.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(-c5cn(C)cn5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5092631 IC50 1000.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(C5CC5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5075947 IC50 1000.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(C5CCCC5)c5c(N)ncnc54)C[C@@H]3O)cc2n1 CHEMBL5074691 IC50 1000.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(C5CCCC5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5081974 IC50 1000.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(CC5CC5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5081886 IC50 1000.0 nM
CNc1ccc2ccc(CC[C@H]3O[C@@H](n4cc(C5CCCC5)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5078232 IC50 1000.0 nM
CN(C)c1ccc2ccc(OC[C@H]3O[C@@H](n4cc(C5CCCC5)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5090183 IC50 1000.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(Cl)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5078304 IC50 1000.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(Br)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5089013 IC50 1000.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(Cl)c5c(N)ncnc54)C[C@@H]3O)cc2n1 CHEMBL5075405 IC50 1000.0 nM
CNc1ccc2ccc(CC[C@H]3C[C@@H](n4cc(C)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5078250 IC50 1000.0 nM
CNc1ccc2ccc(CC[C@H]3C[C@@H](n4cc(CO)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5069625 IC50 1000.0 nM
CCNc1ccc2ccc(CC[C@H]3C[C@@H](n4cc(C5CCCC5)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5091630 IC50 1000.0 nM
CNc1ccc2ccc(CC[C@H]3C[C@@H](n4cc(C5CCCC5)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5094227 IC50 1000.0 nM
CNc1ccc2ccc(CC[C@H]3C[C@@H](n4cc(C5CCCCC5)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5072684 IC50 1000.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(Cl)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5072769 IC50 1000.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(Br)c5c(N)ncnc54)[C@H](O)[C@@H]3O)cc2n1 CHEMBL5085252 IC50 1000.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc([C@H]5CCCO5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5083485 IC50 1000.0 nM
Cn1ccc(-c2cn([C@@H]3C[C@H](COc4ccc5ccc(N6CCC6)nc5c4)[C@@H](O)C3)c3ncnc(N)c23)n1 CHEMBL5077214 IC50 1000.0 nM
Cn1ccc(-c2cn([C@@H]3O[C@H](COc4ccc5ccc(N6CC(O)C6)nc5c4)[C@@H](O)[C@@H]3F)c3ncnc(N)c23)n1 CHEMBL5077410 IC50 1000.0 nM
Cn1ccc(-c2cn([C@H]3C[C@H](O)[C@@H](COc4ccc5ccc(NC6CC6)nc5c4)O3)c3ncnc(N)c23)n1 CHEMBL5084990 IC50 1000.0 nM
Cn1ccc(-c2cn([C@@H]3C[C@H](CCc4ccc5ccc(N6CCC6)nc5c4)[C@@H](O)C3)c3ncnc(N)c23)n1 CHEMBL5085254 IC50 1000.0 nM
Cc1ccn(-c2cn([C@@H]3O[C@H](COc4ccc5ccc(N6CCC6)nc5c4)[C@@H](O)[C@@H]3F)c3ncnc(N)c23)n1 CHEMBL5075912 IC50 1000.0 nM
CNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(-c5cc[nH]n5)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5093104 IC50 1000.0 nM
CCNc1ccc2ccc(OC[C@H]3O[C@@H](n4cc(Cl)c5c(N)ncnc54)[C@@H](F)[C@@H]3O)cc2n1 CHEMBL5089979 IC50 1000.0 nM
CCc1cc(N)c2ccc(OCc3cncc(-n4cc(C5CCCC5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5081990 IC50 1000.0 nM
CNc1ccc2ccc(OCc3cncc(-n4ccc5c(N)ncnc54)n3)cc2n1 CHEMBL5088365 IC50 1000.0 nM
CCc1cc(NCCOC)c2ccc(OCc3cncc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5075944 IC50 1000.0 nM
CNc1ccc2ccc(OCc3cncc(-c4cn(C5CCCC5)c5c(N)ncnc45)c3)cc2n1 CHEMBL5089986 IC50 1000.0 nM
CNc1ccc2ccc(OCc3cncc(-n4cc(Cl)c5c(N)ncnc54)n3)cc2n1 CHEMBL5082370 IC50 1000.0 nM
CNc1ccc2ccc(OCc3cncc(-n4cc(CC5CC5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5087153 IC50 1000.0 nM
CNc1ccc2ccc(OCc3cncc(-n4cc(C5CCCC5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5080171 IC50 1000.0 nM
CCNc1ccc2ccc(OCc3cncc(-n4cc(Cl)c5c(N)ncnc54)c3)cc2n1 CHEMBL5091930 IC50 1000.0 nM
CNc1ccc2ccc(OCc3cncc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5086804 IC50 1000.0 nM
CNc1ccc2ccc(OCc3cncc(-n4cc(Cl)c5c(N)ncnc54)c3)cc2n1 CHEMBL5077428 IC50 1000.0 nM
CC(C)c1nc(NCCN(C)C)c2ccc(OCc3cncc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5086772 IC50 1000.0 nM
CN(C)CCNc1cc(C2CCC2)nc2cc(OCc3cncc(-n4ccc5c(N)ncnc54)c3)ccc12 CHEMBL5094936 IC50 1000.0 nM
CC(C)c1cc(N2CCNCC2)c2ccc(OCc3cncc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5088361 IC50 1000.0 nM
CCc1cc(N2CCOCC2)c2ccc(OCc3cncc(-n4ccc5c(N)ncnc54)c3)cc2n1 CHEMBL5090894 IC50 1000.0 nM
CNc1ccc2ccc(CCc3cncc(-n4cc(C5CCCC5)c5c(N)ncnc54)n3)cc2n1 CHEMBL5083121 IC50 1000.0 nM
CNc1ccc2ccc(OCc3cncc(-n4cc([C@H]5CCCO5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5082368 IC50 1000.0 nM
CCc1cc(N2CCNCC2)c2ccc(OCc3cncc(-n4cc(-c5ccn(C)n5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5089030 IC50 1000.0 nM
Nc1ncnc2c1c(C1CCCO1)cn2-c1cncc(CCc2ccc3ccc(N4CCC4)nc3c2)c1 CHEMBL5092445 IC50 1000.0 nM
CCNc1ccc2ccc(OCc3cncc(-n4cc(-c5ccn(C)n5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5070057 IC50 1000.0 nM
CCc1cc(NC)c2ccc(OCc3cncc(-n4cc(-c5ccn(C)n5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5082342 IC50 1000.0 nM
CCc1cc(N(C)C2CC2)c2ccc(OCc3cncc(-n4cc(-c5ccn(C)n5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5090709 IC50 1000.0 nM
CCc1cc(N(C)CC2CC2)c2ccc(OCc3cncc(-n4cc(-c5ccn(C)n5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5074036 IC50 1000.0 nM
CCc1cc(NCCOC)c2ncc(OCc3cncc(-n4cc(-c5ccn(C)n5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5077244 IC50 1000.0 nM
CCc1cc(N(C)CCN(C)C)c2ccc(CCc3cncc(-n4cc(-c5ccn(C)n5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5090607 IC50 1000.0 nM
CCc1cc(NCCN(C)C)c2c(F)cc(CCc3cncc(-n4cc(-c5ccn(C)n5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5079855 IC50 1000.0 nM
CNc1ccc2ccc(OCc3cncc(-n4cc(-c5ccc(C)o5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5076821 IC50 1000.0 nM
CNc1ccc2ccc(OCc3cncc(-n4cc(-c5ccc(CNCCS(C)(=O)=O)o5)c5c(N)ncnc54)c3)cc2n1 CHEMBL5080806 IC50 1000.0 nM