O=C1N[C@@](c2ccc(OCCCC(F)(F)F)cc2F)(C(F)(F)F)CC(c2ccc(C3CC3)s2)=C1c1nnn[nH]1 CHEMBL4457459 IC50 0.2 nM
CCc1ccc(-c2cc(-c3ccc(OCCCCCC(F)(F)F)cc3C(F)(F)F)[nH]c(=O)c2-c2nn[nH]n2)s1 CHEMBL4564881 IC50 0.3 nM
O=C(CCNC1Cc2ccccc2C1)N1CCc2nc(SC3CCC3)n(-c3ccccc3)c(=O)c2C1 CHEMBL4572662 IC50 0.38 nM
COc1ccc(NC(=O)C2=C(c3ccc(C)cc3)C[C@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cc1 CHEMBL3893594 IC50 0.63 nM
O=C(CNCCCCCOc1ccc(C(F)(F)F)cc1)N1CCc2nc(SC3CCC3)n(-c3ccccc3)c(=O)c2C1 CHEMBL4463750 IC50 0.64 nM
CC(C)(O)c1ccc(C2=C(CNC(=O)CS(C)(=O)=O)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)nc1 CHEMBL4560153 IC50 0.73 nM
CC(=O)Nc1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(CCc1ccccc1)CC2 CHEMBL3581716 IC50 1.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccc(OC(F)(F)F)cc3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3961967 IC50 1.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccc(C(F)(F)F)cc3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3965215 IC50 1.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccc(O)cc3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3981198 IC50 1.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccno3)C(=O)NC(c3ccc(OCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3937187 IC50 1.0 nM
O=C1NC(c2ccc(OCCCCCC(F)(F)F)cc2F)(C(F)(F)F)CC(c2ccc(OC(F)F)cc2)=C1c1nn[nH]n1 CHEMBL3943858 IC50 1.0 nM
O=C1NC(c2ccc(OCCCCCC(F)(F)F)c(F)c2)(C(F)(F)F)CC(c2ccc3ccccc3c2)=C1c1nn[nH]n1 CHEMBL3932509 IC50 1.0 nM
CS(=O)(=O)NC(=O)C1=C(c2ccc(C(F)F)cc2)C[C@](c2ccc(OCCCCCC(F)(F)F)cc2F)(C(F)(F)F)NC1=O CHEMBL3986069 IC50 1.0 nM
CS(=O)(=O)NC(=O)C1=C(c2ccc(C3CC3)cc2)C[C@](c2ccc(OCCCCCC(F)(F)F)cc2F)(C(F)(F)F)NC1=O CHEMBL3960802 IC50 1.0 nM
O=C(CCNCC1COc2ccccc2O1)N1CCc2nc(SC3CCC3)n(-c3ccccc3)c(=O)c2C1 CHEMBL4465236 IC50 1.1 nM
CC(=O)Nc1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(CCc1ccc(F)cc1)CC2 CHEMBL3581717 IC50 1.2 nM
CCC1(CC)CNc2ccc(S(=O)(=O)Nc3ccc(F)cc3F)cc2C(=O)N1 CHEMBL2376316 pIC50 1.585 nM
C[C@H](c1cc(F)cc(F)c1)N1CCc2ccc(S(=O)(=O)Nc3nc(C(=O)N4CCCC4)no3)cc2C1 CHEMBL4469060 IC50 1.6 nM
Cc1ccc(C2=C(C(=O)NC3CCCC3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL4847167 IC50 1.9 nM
O=C1N[C@@](c2ccc(OCCCC(F)(F)F)cc2F)(C(F)(F)F)CC(c2ccn(CC3CC3)n2)=C1c1nnn[nH]1 CHEMBL5401452 IC50 1.9 nM
O=C1N[C@@](c2ccc(OCCCC(F)(F)F)cc2F)(C(F)(F)F)CC(c2ncc(C3CC3)s2)=C1n1nn[nH]c1=O CHEMBL4542050 IC50 1.9 nM
Cc1ccc(NC(=O)C2=C(c3ccc(C)cc3)CC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cc1 CHEMBL3972008 IC50 2.0 nM
COc1ccc(NC(=O)C2=C(c3ccc(C)cc3)CC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cc1F CHEMBL3950677 IC50 2.0 nM
COc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)c(F)c1 CHEMBL3973007 IC50 2.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(OC(F)F)cc2)=C1NC(=O)c1ccno1 CHEMBL3934758 IC50 2.0 nM
Cc1ccc(C2=C(NC(=O)c3cc(Br)no3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3954459 IC50 2.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc3c(c2)CCCC3)=C1c1nn[nH]n1 CHEMBL3972745 IC50 2.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(OC(F)F)cc2)=C1NC(=O)c1ccncc1 CHEMBL3961201 IC50 2.0 nM
O=C1NC(c2ccc(OCCCCCC(F)(F)F)cc2F)(C(F)(F)F)CC(c2ccc3ccccc3c2)=C1c1nn[nH]n1 CHEMBL3937275 IC50 2.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2F)(C(F)(F)F)CC(c2ccc(CC3CC3)cc2)=C1c1nn[nH]n1 CHEMBL3936621 IC50 2.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)cc1 CHEMBL3966409 IC50 2.0 nM
Cc1ccc(C2=C(NC(=O)CS(C)(=O)=O)C(=O)NC(c3ccc(OCc4ccccc4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3942087 IC50 2.0 nM
O=C(Nc1cccnc1)C1=C(c2ccc(OC(F)F)cc2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3974906 IC50 2.0 nM
COc1ccc(NC(=O)C2=C(c3ccc(C)cc3F)CC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cc1 CHEMBL3897918 IC50 2.0 nM
CCCCCCC#CC1(C(F)(F)F)CC(c2ccc(C)cc2)=C(NC(=O)CNS(C)(=O)=O)C(=O)N1 CHEMBL3927790 IC50 2.0 nM
CCCCCCCc1cnc([C@]2(C(F)(F)F)CC(c3ccc(C)cc3)=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N2)s1 CHEMBL3934653 IC50 2.0 nM
O=C1N[C@@](c2ccc(OCCCC(F)(F)F)cc2F)(C(F)(F)F)CC(c2ncc(C3CC3)s2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3948720 IC50 2.0 nM
O=C1N[C@@](c2ccc(CCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccn(CC3CC3)n2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3931648 IC50 2.0 nM
CCc1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@](C)(c3ccc(OCCCC(F)(F)F)cc3)C2)cc1 CHEMBL3969017 IC50 2.0 nM
CC(=O)Nc1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2ccn(CCc3ccccc3)c12 CHEMBL3581718 IC50 2.1 nM
O=C1NCCCN1c1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(C(=O)OCc1ccccc1)CC2 CHEMBL3581732 IC50 2.2 nM
COc1ccc(NS(=O)(=O)c2cc3c(c(NC(C)=O)c2)N(CCc2ccccc2)CC3)cc1 CHEMBL3581715 IC50 2.2 nM
O=C1N[C@@](c2ccc(OCCCC(F)(F)F)cc2F)(C(F)(F)F)CC(c2ncc(C3CC3)s2)=C1c1nnn[nH]1 CHEMBL5411481 IC50 2.4 nM
O=C1NCCN1c1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(C(=O)Nc1ccc(C(F)(F)F)cc1)CC2 CHEMBL3581736 IC50 2.5 nM
COc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3963586 IC50 2.5 nM
CCc1ccc(C2=C(n3nn[nH]c3=O)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)s1 CHEMBL5416977 IC50 2.5 nM
Cc1ccc(C2=C(c3nnn[nH]3)C(=O)N[C@@](c3ccc(CCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL4863471 IC50 2.6 nM
Cc1ccc(C2=C(c3nnn[nH]3)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)cc1 CHEMBL4869563 IC50 2.6 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3919277 IC50 3.0 nM
Cc1ccc(C2=C(NC(=O)c3cc(C)no3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2(F)F)cc1 CHEMBL3963796 IC50 3.0 nM
CCCCOc1ccc(C2(C(F)(F)F)CC(c3ccc(OC)cc3)=C(NC(=O)c3ccno3)C(=O)N2)cc1 CHEMBL3925829 IC50 3.0 nM
COc1ccc(C2=C(NC(=O)c3cc(C)no3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3970273 IC50 3.0 nM
CS(=O)(=O)CC(=O)NC1=C(c2ccc(OCC(F)F)cc2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3894584 IC50 3.0 nM
Cc1ccc(C2=C(C(=O)Nc3cc(C)no3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3950805 IC50 3.0 nM
CCOP(=O)(CC(=O)NC1=C(c2ccc(C)cc2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O)OCC CHEMBL3979778 IC50 3.0 nM
CCOc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)cc1 CHEMBL3894145 IC50 3.0 nM
O=C1NC(c2ccc(OCCCCCC(F)(F)F)c(F)c2)(C(F)(F)F)CC(c2ccc(CC(F)(F)F)cc2)=C1c1nn[nH]n1 CHEMBL3920071 IC50 3.0 nM
CCCCCCC#Cc1ccc(C2(C(F)(F)F)CC(c3ccc(OC(F)F)cc3)=C(c3nn[nH]n3)C(=O)N2)cc1F CHEMBL3912709 IC50 3.0 nM
CCCCCCCC#CC1(C(F)(F)F)CC(c2ccc(C)cc2)=C(NC(=O)c2nnn[nH]2)C(=O)N1 CHEMBL3927100 IC50 3.0 nM
COc1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)cc1 CHEMBL3959513 IC50 3.0 nM
CC(C)n1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(CCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)c1 CHEMBL3973568 IC50 3.0 nM
O=C1N[C@@](c2ccc(OCCCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccn(CC3CC3)n2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3922700 IC50 3.0 nM
O=C1CCCN1c1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(C(=O)Nc1ccc(C(F)(F)F)cc1)CC2 CHEMBL3581734 IC50 3.1 nM
CCC1(CC)NC(=O)c2cc(S(=O)(=O)Nc3ccc(F)cc3F)ccc2NC1=O CHEMBL2376310 pIC50 3.162 nM
O=C1NCCN1c1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(C(=O)OCc1ccccc1)CC2 CHEMBL3581730 IC50 3.4 nM
CC(C)(C)c1ccc(NC(=O)N2CCc3cc(S(=O)(=O)Nc4ccc(F)cc4F)cc(N4CCCC4=O)c32)cc1 CHEMBL3581735 IC50 3.6 nM
CC(=O)Nc1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(CCCc1ccccc1)CC2 CHEMBL3581724 IC50 3.7 nM
CS(=O)(=O)N[C@@H](c1ccc(CNC[C@H]2COc3cccnc3O2)cc1)C(F)(F)F CHEMBL3545611 IC50 3.8 nM
CCC1(C)NC(=O)c2cc(S(=O)(=O)Nc3ccc(OC)cc3)ccc2NC1=O CHEMBL2376329 pIC50 3.981 nM
Cc1ccc(C2=C(C(=O)Nc3ccccc3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3902676 IC50 4.0 nM
N#CC1=C(c2ccc(OC(F)F)cc2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3955595 IC50 4.0 nM
Cc1ccc(C2=C(c3ccc(OC(F)(F)F)cc3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3986742 IC50 4.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3977050 IC50 4.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)C(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3897522 IC50 4.0 nM
COc1ccc(C2=C(n3cnnn3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3898522 IC50 4.0 nM
COc1cc(C(=O)NC2=C(c3ccc(C)cc3)CC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)on1 CHEMBL3901484 IC50 4.0 nM
O=C1NC(c2ccc(OCCCCCC(F)(F)F)cc2F)(C(F)(F)F)CC(c2ccc(CC(F)(F)F)cc2)=C1c1nn[nH]n1 CHEMBL3918640 IC50 4.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCC4CC4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3903094 IC50 4.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)c(F)c1 CHEMBL3931072 IC50 4.0 nM
Cc1ccc(C2=C(NC(=O)c3nnn[nH]3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3903831 IC50 4.0 nM
CCCCCCCC#CC1(C(F)(F)F)CC(c2ccc(OC(F)F)cc2)=C(NC(=O)CS(C)(=O)=O)C(=O)N1 CHEMBL3918163 IC50 4.0 nM
Cc1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)cc1 CHEMBL3975920 IC50 4.0 nM
CCCCCCC#C[C@]1(C(F)(F)F)CC(c2ccc(C)cc2)=C(C(=O)NS(C)(=O)=O)C(=O)N1 CHEMBL4111538 IC50 4.0 nM
CC(C)(C)c1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3914250 IC50 4.0 nM
O=C1N[C@@](c2ccc(OCCCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(CC3CC3)cc2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3925649 IC50 4.0 nM
O=C1N[C@@](c2cnn(CCCCCC(F)(F)F)c2)(C(F)(F)F)CC(c2ccc(C3CC3)s2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3941701 IC50 4.0 nM
CS(=O)(=O)NC(=O)C1=C(c2ccc(C3CC3)s2)C[C@](c2ccc(OCCCC(F)(F)F)cc2F)(C(F)(F)F)NC1=O CHEMBL3961911 IC50 4.0 nM
CC(C)n1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)c1 CHEMBL3932124 IC50 4.0 nM
O=C1N[C@@](c2cnn(CCCCCCC(F)(F)F)c2)(C(F)(F)F)CC(c2ccc3c(c2)CCCC3)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3973952 IC50 4.0 nM
CCOC(=O)CCc1ccc(CN2CC(C(=O)N3CCc4nc(SC5CCCCC5)n(-c5ccccc5)c(=O)c4C3)C2)cc1 CHEMBL4466376 IC50 4.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccc(OC(F)(F)F)cc3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL4868038 IC50 4.2 nM
Cc1ccc(C2=C(n3cnnn3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL5398266 IC50 4.5 nM
O=C1N[C@@](c2ccc(OCCCC(F)(F)F)cc2F)(C(F)(F)F)CC(c2ccn(CC3CC3)n2)=C1n1nn[nH]c1=O CHEMBL5418882 IC50 4.6 nM
Cc1ccc(C2=C(c3nnn[nH]3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3966030 IC50 5.0 nM
CCOc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3943482 IC50 5.0 nM
COc1ccc(NC(=O)C2=C(c3ccc(C)cc3)CC(c3ccc(OCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cc1 CHEMBL3967083 IC50 5.0 nM
COc1ccc(NC(=O)C2=C(c3ccc(C)cc3)CC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cn1 CHEMBL3932589 IC50 5.0 nM
CNC(=O)C1=C(c2ccc(C)cc2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3907612 IC50 5.0 nM
CCc1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)s1 CHEMBL3901123 IC50 5.0 nM
Cc1ccc(C2=C(C(=O)NS(=O)(=O)C(F)(F)F)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3973237 IC50 5.0 nM
O=C1N[C@@](c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(C3CC3)s2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3972926 IC50 5.0 nM
COc1ccc(NC(=O)C2=C(c3ccc(C)cc3)C[C@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cn1 CHEMBL4872250 IC50 5.0 nM
Cc1ccc(C2=C(c3nnn[nH]3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)cc1 CHEMBL4875367 IC50 5.0 nM
CNC(=O)C1=C(c2ccc(C)cc2)C[C@](c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL4863703 IC50 5.2 nM
CCCCSc1ccc([C@]2(C(F)(F)F)CC(c3ccc(C)cc3)=C(c3nnn[nH]3)C(=O)N2)cc1 CHEMBL4851952 IC50 5.5 nM
Cc1ccc(C2=C(C(=O)NC3CCC3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3892111 IC50 6.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(OC(F)F)cc2)=C1n1cnnn1 CHEMBL3957613 IC50 6.0 nM
CCCCCC#CC1(C(F)(F)F)CC(c2ccc(C)cc2)=C(c2cn[nH]n2)C(=O)N1 CHEMBL3937526 IC50 6.0 nM
COc1ccc(C(=O)NC2=C(c3ccc(C)cc3)CC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)nn1 CHEMBL3961365 IC50 6.0 nM
Cc1ccc(C2=C(C(=O)NS(C)(=O)=O)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3916140 IC50 6.0 nM
O=C1N[C@@](c2ccc(OCCCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(OC(F)F)cc2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3889610 IC50 6.0 nM
CS(=O)(=O)NC(=O)C1=C(c2ccc(C3CC3)s2)C[C@](c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3939945 IC50 6.0 nM
CS(=O)(=O)NC(=O)C1=C(c2ccn(C3CC3)n2)C[C@](c2ccc(OCCCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3937991 IC50 6.0 nM
O=C1N[C@@](c2ccc(OCCCCCC(F)(F)F)cc2F)(C(F)(F)F)CC(c2ccn(C3CC3)n2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3933213 IC50 6.0 nM
Cc1ccc(C2=C(c3nnn[nH]3)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL4878564 IC50 6.1 nM
CC[C@]1(C)NC(=O)c2cc(S(=O)(=O)Nc3ccc(F)cc3F)ccc2NC1=O CHEMBL2376303 IC50 6.3 nM
O=C1CCCN1c1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(CCc1ccccc1)CC2 CHEMBL3581727 IC50 6.7 nM
COc1ccc(NC(=O)C2=C(c3ccc(C)cc3)CC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cc1 CHEMBL2441600 IC50 6.7 nM
Cc1ccc(C2=C(C(=O)Nc3nn[nH]n3)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3984454 IC50 7.0 nM
COc1ccc(NC(=O)C2C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)CC2c2ccc(C)cc2)cc1 CHEMBL3917264 IC50 7.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccc(F)cc3)C(=O)NC(c3ccc(Oc4ccccc4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3978458 IC50 7.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccc(C)c(F)c3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3945212 IC50 7.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccc(-c4nnn[nH]4)nc3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3929176 IC50 7.0 nM
COc1ccc(C(=O)NC2=C(c3ccc(C)cc3)CC(c3cnn(CCCCCC(F)(F)F)c3)(C(F)(F)F)NC2=O)cc1 CHEMBL3983628 IC50 7.0 nM
CN(C)c1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3932213 IC50 7.0 nM
COc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3927515 IC50 7.0 nM
COc1ccc(C2=C(NC(=O)CS(C)(=O)=O)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3926123 IC50 7.0 nM
CCCCCC#CC1(C(F)(F)F)CC(c2ccc(C)cc2)=C(c2nn[nH]n2)C(=O)N1 CHEMBL3928233 IC50 7.0 nM
CC(C)(C)c1ccc(C2=C(C(=O)NS(C)(=O)=O)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3908423 IC50 7.0 nM
CS(=O)(=O)NC(=O)C1=C(c2ccn(C3CCC3)n2)C[C@](c2ccc(OCCCC(F)(F)F)cc2F)(C(F)(F)F)NC1=O CHEMBL3903101 IC50 7.0 nM
CCOc1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)cc1 CHEMBL3962980 IC50 7.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccc(-c4nnn[nH]4)cc3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)cc1 CHEMBL4441959 IC50 7.0 nM
COc1ccc(NC(=O)C2=C(c3ccc(C)cc3)C[C@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)nn1 CHEMBL4865613 IC50 7.1 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(O)=N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3912712 IC50 7.1 nM
O=C1CCCCN1c1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(CCc1ccccc1)CC2 CHEMBL3581728 IC50 7.3 nM
Cc1ccc(C2=C(C(=O)NC3CCC3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL4854178 IC50 7.3 nM
Cn1nc(C(F)(F)F)cc1-c1cnc(N2CCc3cc(S(=O)(=O)Nc4c(F)cc(Cl)cc4F)cc(N4CCCC4=O)c32)nc1 CHEMBL4455357 IC50 7.8 nM
Cc1ccc(C2=C(C3N=NN=N3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3902329 IC50 8.0 nM
Cc1ccc(C2=C(NC(=O)c3nnc(C)o3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3930463 IC50 8.0 nM
O=C1NC(c2ccc(OCCCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(OCC(F)F)cc2)=C1c1nn[nH]n1 CHEMBL3940547 IC50 8.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)cc1 CHEMBL3901379 IC50 8.0 nM
COc1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3911222 IC50 8.0 nM
CC(C)n1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)n1 CHEMBL3906412 IC50 8.0 nM
O=C1N[C@@](c2ccc(OCCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(C3CC3)s2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3956745 IC50 8.0 nM
CS(=O)(=O)NC(=O)C1=C(c2ccn(CC3CCC3)n2)C[C@](c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3908799 IC50 8.0 nM
COc1ccc(NC(=O)C2=C(c3ccc(C)cc3C)CC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cc1 CHEMBL3890409 IC50 9.0 nM
Cc1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ncc(CCCCCCC(F)(F)F)s3)(C(F)(F)F)C2)cc1 CHEMBL3977222 IC50 9.0 nM
Cc1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3Cl)(C(F)(F)F)C2)cc1 CHEMBL3977890 IC50 9.0 nM
CCC1(C)NC(=O)c2cc(S(=O)(=O)Nc3ccc(F)cc3F)ccc2NC1=O CHEMBL2376302 pIC50 10.0 nM
O=C1CCCCN1c1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(C(=O)OCc1ccccc1)CC2 CHEMBL3581731 IC50 10.0 nM
Cc1ccc(C2=C(C(=O)Nc3nn[nH]n3)C(=O)NC(c3cccc(C4=CCCCC4)c3)(C(F)(F)F)C2)cc1 CHEMBL3893112 IC50 10.0 nM
COc1ccc(C2=C(n3cnnn3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)c(F)c1 CHEMBL3894666 IC50 10.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)c(F)c3)(C(F)(F)F)C2)cc1 CHEMBL3978021 IC50 10.0 nM
COc1cnc(NC(=O)C2=C(c3ccc(C)cc3)CC(c3ccc(OCCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cn1 CHEMBL3973375 IC50 10.0 nM
O=C1N[C@@](c2ccc(CCCCC(F)(F)F)cc2F)(C(F)(F)F)CC(c2ccn(CC3CC3)n2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3895365 IC50 10.0 nM
COc1cnc(NC(=O)C2=C(c3ccc(C)cc3)C[C@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cn1 CHEMBL4872517 IC50 10.0 nM
Cc1ccc(C2=C(c3nnn[nH]3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)c(F)c3)(C(F)(F)F)C2)cc1 CHEMBL4872367 IC50 10.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc3ccccc3c2)=C1c1nn[nH]n1 CHEMBL3981752 IC50 11.0 nM
COc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1C CHEMBL3891440 IC50 11.0 nM
Cc1ccc(C2=C(NC(=O)c3cccnc3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3897628 IC50 11.0 nM
CCCCCCC#CC1(C(F)(F)F)CC(c2ccc(C)cc2)=C(NC(=O)c2cccnc2)C(=O)N1 CHEMBL3969193 IC50 11.0 nM
Cc1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](C#CCCCCCC(F)(F)F)(C(F)(F)F)C2)cc1 CHEMBL4109701 IC50 11.0 nM
COc1ccc(C2=C[C@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC(=O)C2(F)C#N)cc1 CHEMBL3977537 IC50 12.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccccc3Cl)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3925235 IC50 12.0 nM
COc1ccc(C(=O)NC2=C(c3ccc(C)cc3)CC(c3ccc(OCCCC(F)(F)F)cc3)NC2=O)cc1 CHEMBL3985857 IC50 12.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(CC(F)(F)F)cc2)=C1c1nn[nH]n1 CHEMBL3981365 IC50 12.0 nM
CCc1ccc(C2=C(C(=O)NS(C)(=O)=O)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)s1 CHEMBL3961143 IC50 12.0 nM
Cc1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3984120 IC50 12.0 nM
CS(=O)(=O)NC(=O)C1=C(c2ccc(C(F)F)cc2)C[C@](c2ccc(OCCCC(F)(F)F)cc2F)(C(F)(F)F)NC1=O CHEMBL3963059 IC50 12.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccc(OC(F)(F)F)cc3)C(=O)NC(C)(c3ccc(OCCCC(F)(F)F)cc3)C2)cc1 CHEMBL3895659 IC50 13.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCc4ccccc4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3985062 IC50 13.0 nM
CCCCCc1ccc(C2(C(F)(F)F)CC(c3ccc(C)cc3)=C(C(=O)Nc3ccc(F)cc3)C(=O)N2)cc1 CHEMBL3916973 IC50 13.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(OC(F)F)cc2)=C1c1nn[nH]n1 CHEMBL3911717 IC50 13.0 nM
N#CC1=C(c2ccc(Cl)c(F)c2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3894088 IC50 13.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCCCC(F)(F)F)c(C)c3)(C(F)(F)F)C2)cc1 CHEMBL3933693 IC50 13.0 nM
O=C1N[C@@](c2ccc(OCCCC(F)(F)F)cc2F)(C(F)(F)F)CC(c2ccn(CC3CC3)n2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3984366 IC50 13.0 nM
O=C1N[C@@](c2cnn(CCCCCC(F)(F)F)c2)(C(F)(F)F)CC(c2ccc3c(c2)CCCC3)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3979439 IC50 13.0 nM
O=C(Nc1ccc(S(=O)(=O)Nc2ccc(F)cc2F)cc1N1CCCC1=O)OCc1ccccc1 CHEMBL3581729 IC50 14.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3931860 IC50 14.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(OC(F)(F)F)cc2)=C1c1nn[nH]n1 CHEMBL3967950 IC50 14.0 nM
Cc1ccc(C2=C(n3ccnn3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL5424825 IC50 14.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCC(C)C)cc3)(C(F)(F)F)C2)cc1 CHEMBL3892785 IC50 15.0 nM
COc1ccc(C2(C(F)(F)F)CC(c3ccc(C)cc3)=C(C(=O)Nc3ccc(F)cc3)C(=O)N2)cc1 CHEMBL3969862 IC50 15.0 nM
N#CC1=C(c2ccc3ccccc3c2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3934088 IC50 15.0 nM
Cc1ccc(C2=C(NC(=O)CS(C)(=O)=O)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3904214 IC50 15.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1Cl CHEMBL3963774 IC50 15.0 nM
Cc1ccc(C2=C(C(=O)NCCc3ccccc3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3911689 IC50 16.0 nM
Cc1ccc(C2=C(c3cn[nH]n3)C(=O)NC(C#CCCc3ccccc3)(C(F)(F)F)C2)cc1 CHEMBL3916628 IC50 16.0 nM
Cc1ccc(C2=C(c3cn[nH]n3)C(=O)NC(C#CCCC(C)C)(C(F)(F)F)C2)cc1 CHEMBL3986392 IC50 16.0 nM
Cc1ccc(C2=C(C(=O)NS(C)(=O)=O)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3968727 IC50 16.0 nM
CS(=O)(=O)NC(=O)C1=C(c2ccn(C3CC3)n2)C[C@](c2ccc(OCCCC(F)(F)F)cc2F)(C(F)(F)F)NC1=O CHEMBL3916697 IC50 16.0 nM
O=C1N[C@@](c2ccc(OCCCC(F)(F)F)cc2F)(C(F)(F)F)CC(c2ccn(C3CCC3)n2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3940109 IC50 16.0 nM
CCS(=O)(=O)NC(=O)C1=C(c2ccc(C)cc2)C[C@](c2ccc(OCCCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3974338 IC50 17.0 nM
CN(C)c1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3894560 IC50 17.0 nM
CCS(=O)(=O)NC(=O)C1=C(c2ccc(C)cc2)C[C@](c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3921634 IC50 17.0 nM
O=C1N[C@@](c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccn(CC3CCC3)n2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3920421 IC50 17.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3955972 IC50 18.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3906382 IC50 18.0 nM
Cc1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3977767 IC50 18.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCC4CC(F)(F)C4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3905665 IC50 19.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(C#CCC4CCCCC4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3942655 IC50 19.0 nM
O=C1NC(c2ccc(OCCCCCC(F)(F)F)c(F)c2)(C(F)(F)F)CC(c2ccc(OC(F)F)cc2)=C1c1nn[nH]n1 CHEMBL3910068 IC50 19.0 nM
CC(C)(C)c1ccc(C2=C(C(=O)NS(C)(=O)=O)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3982352 IC50 19.0 nM
CC(C)(C)c1cc(C(C)(C)C)nc(N2CCn3c(nnc3-c3ccc(OC(F)(F)F)cc3)C2)n1 CHEMBL4452833 IC50 19.0 nM
CC[C@]1(C)NC(=O)c2cc(S(=O)(=O)Nc3ccc(C(F)(F)F)cc3)ccc2NC1=O CHEMBL2376320 pIC50 19.95 nM
COc1ccc(C2(C(F)(F)F)CC(c3ccc(C)cc3)=C(C#N)C(=O)N2)cc1 CHEMBL3964622 IC50 20.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccc(F)cc3)C(=O)NC(c3ccc(OCc4ccccc4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3948419 IC50 20.0 nM
CCCCCNC(=O)C1=C(c2ccc(C)cc2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3924121 IC50 20.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3940914 IC50 20.0 nM
Cc1ccc(C2=C(C(=O)NC3CCCCC3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3920128 IC50 20.0 nM
CC(C)n1ccc(C2=C(C(=O)NS(C)(=O)=O)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)n1 CHEMBL3931082 IC50 20.0 nM
CCCCOc1ccc(C2(C(F)(F)F)CC(c3ccc(C)cc3)=C(C#N)C(=O)N2)cc1 CHEMBL3890110 IC50 21.0 nM
Cc1ccc(C2=C(C(=O)NC3CC3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3900943 IC50 21.0 nM
CCCCCCCC#CC1(C(F)(F)F)CC(c2ccc(OCC)cc2)=C(NC(=O)CS(C)(=O)=O)C(=O)N1 CHEMBL3902649 IC50 21.0 nM
Cc1ccc(C2=C(C(=O)NC3CC3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL4865861 IC50 21.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(C3CC3)cc2)=C1c1nn[nH]n1 CHEMBL3909151 IC50 22.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1F CHEMBL3954288 IC50 22.0 nM
CS(=O)(=O)NC(=O)C1=C(c2ccc3c(c2)CCC3)C[C@](c2ccc(OCCCC(F)(F)F)cc2F)(C(F)(F)F)NC1=O CHEMBL3934409 IC50 22.0 nM
Cc1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](C3CCCCC3)(C(F)(F)F)C2)cc1 CHEMBL3958350 IC50 22.0 nM
CC(=O)Nc1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(Cc1ccccc1)CC2 CHEMBL3581723 IC50 23.0 nM
COc1cccc(-c2ccc(CNC(=O)[C@@H]3C[C@H]3c3ccccc3)c3c2CCN(C(C)=O)C3)c1 CHEMBL3735388 IC50 23.0 nM
CN(C)S(=O)(=O)NC(=O)C1=C(c2ccc(OC(F)F)cc2)C[C@](c2ccc(OCCCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3968573 IC50 23.0 nM
CC(C)n1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(CCCCC(F)(F)F)cc3)(C(F)(F)F)C2)n1 CHEMBL3916015 IC50 23.0 nM
CS(=O)(=O)NC(=O)C1=C(c2ccn(CC3CC3)n2)C[C@](c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3945642 IC50 23.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccc(Cl)cc3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3955945 IC50 24.0 nM
Cc1ccc(C2=C(NC(=O)c3ccccc3C)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3910148 IC50 24.0 nM
Cc1ccc(C2=C(NC(=O)c3ccc(OC(F)F)cc3)C(=O)NC(c3cnn(CCCCCC(F)(F)F)c3)(C(F)(F)F)C2)cc1 CHEMBL3978182 IC50 24.0 nM
CCCCCCC#C[C@]1(C(F)(F)F)CC(c2ccc(OC(F)F)cc2)=C(C(=O)NS(C)(=O)=O)C(=O)N1 CHEMBL4111569 IC50 24.0 nM
CN(C)c1ccc(C2=C(C(=O)NS(C)(=O)=O)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3916634 IC50 24.0 nM
Cc1ccc(C2=C(C(=O)NC3CCCCC3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL4864768 IC50 24.0 nM
COc1ccc(C(=O)NC2=C(c3ccc(C)cc3)CC(c3cnn(CCCCC(F)(F)F)c3)(C(F)(F)F)NC2=O)cc1 CHEMBL3910385 IC50 25.0 nM
Cc1ccc(C2=C(C(=O)NS(=O)(=O)N(C)C)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3908922 IC50 25.0 nM
O=C1N[C@@](c2ccc(OCCCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccn(C3CC3)n2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3931369 IC50 25.0 nM
CC[C@]1(C)NC(=O)c2cc(S(=O)(=O)Nc3ccc(OC(F)F)cc3)ccc2NC1=O CHEMBL2376321 pIC50 25.12 nM
CCC1(C)NC(=O)c2cc(S(=O)(=O)Nc3ccc(OC(F)F)cc3)ccc2NC1=O CHEMBL2376301 pIC50 25.12 nM
CCC1(C)NC(=O)c2cc(S(=O)(=O)Nc3ccc(Cl)cc3)ccc2NC1=O CHEMBL2376325 pIC50 25.12 nM
Cc1ccc(C2=C(C(=O)NS(C)(=O)=O)C(=O)N[C@@](c3ccc(OCc4ccccc4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3941000 IC50 26.0 nM
COc1ccc(NC(=O)C2=C(c3ccc(C)cc3)C[C@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)nc1 CHEMBL4848943 IC50 26.0 nM
CC(C)(C)c1ccc(C2=C(C(=O)NS(C)(=O)=O)C(=O)N[C@](C)(c3ccc(OCCCC(F)(F)F)cc3)C2)cc1 CHEMBL3946794 IC50 27.0 nM
Cc1ccc(C2=C(n3nn[nH]c3=O)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL5417398 IC50 27.0 nM
O=C1CCCN1c1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(C(=O)Nc1ccc(F)cc1)CC2 CHEMBL3581733 IC50 28.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCCCC(F)(F)F)c(F)c3)(C(F)(F)F)C2)cc1 CHEMBL3904511 IC50 28.0 nM
Cc1ccc(C2=C(c3nnn[nH]3)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)c(F)c3)(C(F)(F)F)C2)cc1 CHEMBL4873883 IC50 28.0 nM
COc1cccc(NC(=O)C2=C(c3ccc(C)cc3)CC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)c1 CHEMBL3934122 IC50 29.0 nM
O=C1N[C@@](c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccn(C3CCC3)n2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3917248 IC50 29.0 nM
Cc1ccc(C2=C(NC(=O)c3cc(OCc4ccccc4)no3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3970593 IC50 30.0 nM
CCOc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3943120 IC50 30.0 nM
Cc1ccc(C2=C(C(=O)Nc3nn[nH]n3)C(=O)NC(c3ccc(C4=CCCC4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3905674 IC50 33.0 nM
CCCCCCCC#CC1(C(F)(F)F)CC(c2ccc(C)cc2)=C(c2cn[nH]n2)C(=O)N1 CHEMBL3967215 IC50 33.0 nM
CCS(=O)(=O)NC(=O)C1=C(c2ccc(OC(F)F)cc2)C[C@](c2ccc(OCCCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3892164 IC50 33.0 nM
Cc1ccc(C2=C(NC(=O)c3ccn(C)n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3984655 IC50 34.0 nM
C[C@@]1(c2ccc(OCCCC(F)(F)F)cc2)CC(c2ccn(CC3CC3)n2)=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N1 CHEMBL3971290 IC50 34.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccn(C)n3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL4873488 IC50 34.0 nM
Cc1ccc(C2=C([N+](=O)[O-])C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3900395 IC50 35.0 nM
Cc1ccc(C2=C(NC(=O)c3cn(C)nn3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3972877 IC50 36.0 nM
Cc1ccc(C2=C(NC(=O)c3ccc(OC(F)(F)F)cc3)C(=O)NC(c3cnn(CCCCCC(F)(F)F)c3)(C(F)(F)F)C2)cc1 CHEMBL3911214 IC50 37.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc3c(c2)OCCO3)=C1c1nn[nH]n1 CHEMBL3973736 IC50 37.0 nM
O=C1N[C@@](c2ccc(OCCCC(F)(F)F)cc2F)(C(F)(F)F)CC(c2ccn(CC3CCC3)n2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3947025 IC50 37.0 nM
Cc1cnc(C2=C(c3nnn[nH]3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)nc1 CHEMBL5398400 IC50 37.0 nM
CS(=O)(=O)NC(=O)C1=C(c2ccc(OC(F)F)cc2)C[C@](c2ccc(OCCCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3959974 IC50 38.0 nM
Cc1ccc(C2=C(C(=O)NS(=O)(=O)N(C)C)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3965249 IC50 38.0 nM
CCCCCCCn1ccc(C2(C)CC(c3ccc(C)cc3)=C(C#N)C(=O)N2)n1 CHEMBL3923767 IC50 39.0 nM
CCC1(C)NC(=O)c2cc(S(=O)(=O)Nc3ccc(C(F)(F)F)cc3)ccc2NC1=O CHEMBL2376328 pIC50 39.81 nM
Cc1ccc(C2=C(C(O)Nc3ccccc3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3915349 IC50 40.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(Br)cc2)=C1c1nn[nH]n1 CHEMBL3979414 IC50 40.0 nM
COc1ccccc1NC(=O)C1=C(c2ccc(C)cc2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3907486 IC50 40.0 nM
CC(C)(C)n1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)n1 CHEMBL3953879 IC50 40.0 nM
COc1ccccc1NC(=O)C1=C(c2ccc(C)cc2)C[C@](c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL4860076 IC50 40.0 nM
CC(=O)Nc1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2cnn(CCc3ccc(F)cc3)c12 CHEMBL3581719 IC50 41.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3892057 IC50 41.0 nM
CCOc1ccc(C2=C(C(=O)NS(C)(=O)=O)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)cc1 CHEMBL3934323 IC50 42.0 nM
Cc1ccc(C2=C(c3nnn[nH]3)C(=O)N[C@@](c3ccc(OCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL4869735 IC50 42.0 nM
O=C1OCCN1c1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(C(=O)OCc1ccccc1)CC2 CHEMBL3581739 IC50 43.0 nM
COc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)c(F)c1 CHEMBL3956480 IC50 43.0 nM
CCCCCCCCCCCCCCCCNC(=O)C1(C)CC(c2ccc(C)cc2)=C(C(=O)Nc2ccc(OC)cc2)C(=O)N1 CHEMBL3897024 IC50 43.0 nM
COc1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3982866 IC50 43.0 nM
CC(C)(C)Cn1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)n1 CHEMBL3939452 IC50 43.0 nM
O=C1NC(c2ccc(OCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(OC(F)(F)F)cc2)=C1c1nn[nH]n1 CHEMBL3903041 IC50 44.0 nM
N#CC1=C(c2ccc(OC(F)(F)F)cc2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3963629 IC50 45.0 nM
Cc1ccc(C2=C(C(=O)NS(N)(=O)=O)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3932729 IC50 45.0 nM
Cc1ccc(C2=C(c3nnn[nH]3)C(=O)N[C@@](c3ccc(OCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL4878608 IC50 45.0 nM
COc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3964553 IC50 46.0 nM
CCOc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1F CHEMBL3904013 IC50 46.0 nM
COc1ccc(C(=O)NC2=C(c3ccc(C)cc3)C(F)(F)C(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cc1 CHEMBL3924256 IC50 47.0 nM
COc1ccc(NC(=O)C2=C(c3ccc(C)cc3)CC(C)(C(=O)NCCCCc3ccccc3)NC2=O)cc1 CHEMBL3979985 IC50 47.0 nM
CCn1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)n1 CHEMBL3986454 IC50 47.0 nM
O=C1NC2(CCCC2)C(=O)Nc2ccc(S(=O)(=O)Nc3ccc(Cl)cc3)cc21 CHEMBL2376309 pIC50 50.12 nM
CCCC1(C)NC(=O)c2cc(S(=O)(=O)Nc3ccc(F)cc3F)ccc2NC1=O CHEMBL2376307 pIC50 50.12 nM
COc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3916021 IC50 51.0 nM
COc1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cn1 CHEMBL3906047 IC50 52.0 nM
COc1ccc(C2=C(C(=O)NS(C)(=O)=O)C(=O)N[C@@](c3ccc(OCCCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)cc1 CHEMBL3939757 IC50 52.0 nM
CS(=O)(=O)NC(=O)C1=C(c2ccc(OC(F)F)cc2)C[C@](c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3982558 IC50 54.0 nM
COCc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3925532 IC50 56.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(C#CCOCc4ccccc4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3918228 IC50 56.0 nM
O=c1c2c(nc(SCc3cccnc3)n1-c1ccccc1)CCN(c1nc3cc(C(F)(F)F)ccc3[nH]1)C2 CHEMBL4560833 IC50 56.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCC4CCCC4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3896139 IC50 57.0 nM
Cc1ccc(C2=C(NC(=O)c3cc(F)ccc3Cl)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3920363 IC50 57.0 nM
Cc1ccc(C2=C(c3nnn[nH]3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)nc1 CHEMBL5426368 IC50 57.0 nM
CC(C)(C)C1CCN(Cc2ccc([C@H](NS(C)(=O)=O)C(F)(F)F)cc2)CC1 CHEMBL4535947 IC50 58.0 nM
CCOCc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1F CHEMBL3973230 IC50 59.0 nM
CC(C)(C)Cn1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(CCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)n1 CHEMBL3895566 IC50 59.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(-c4ccccn4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3953569 IC50 60.0 nM
CCCCCCCCNC(=O)C1(C)CC(c2ccc(C)cc2)=C(C(=O)Nc2ccc(OC)cc2)C(=O)N1 CHEMBL3902554 IC50 60.0 nM
CCCCCCC#Cc1ccc(C2(C(F)(F)F)CC(c3ccc(OCC)cc3)=C(c3nn[nH]n3)C(=O)N2)cc1F CHEMBL3909361 IC50 61.0 nM
CC(C)(C)Cn1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)n1 CHEMBL3955750 IC50 62.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3cnn(CCCCC(F)(F)F)c3)(C(F)(F)F)C2)cc1 CHEMBL3901323 IC50 63.0 nM
CC[C@@]1(C)NC(=O)c2cc(S(=O)(=O)Nc3ccc(F)cc3F)ccc2NC1=O CHEMBL2376304 pIC50 63.1 nM
CCC1(C)NC(=O)c2cc(S(=O)(=O)Nc3ccccc3Cl)ccc2NC1=O CHEMBL2376327 pIC50 63.1 nM
Cc1ccc(C2=C(C(=O)Nc3ccc(F)cc3)C(=O)NC(c3ccc(Oc4ccncn4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3907985 IC50 64.0 nM
O=C1N[C@@](c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccn(CC3CC3)n2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3924406 IC50 67.0 nM
CCCCOc1ccc([C@]2(C(F)(F)F)CC(c3ccc(C)cc3)=C(c3nnn[nH]3)C(=O)N2)cc1 CHEMBL4862212 IC50 67.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(C(F)(F)F)cc2)=C1c1nn[nH]n1 CHEMBL3973558 IC50 69.0 nM
O=C1N[C@@](c2ccc(CCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccn(C3CC3)n2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3940541 IC50 72.0 nM
Cc1ccc(C2=C(NC(=O)c3ccc(Cl)nn3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3934793 IC50 75.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3937830 IC50 76.0 nM
CCCCCc1ccc(C2(C(F)(F)F)CC(c3ccc(C)cc3)=C(C#N)C(=O)N2)cc1 CHEMBL3977988 IC50 77.0 nM
Cc1ccc(C2=C(c3nnn[nH]3)C(=O)N[C@@](c3ccc(OCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL4850770 IC50 78.0 nM
O=C1NC2(CCC2)C(=O)Nc2ccc(S(=O)(=O)Nc3ccc(Cl)cc3)cc21 CHEMBL2376308 pIC50 79.43 nM
O=C1N[C@@](c2ccc(OCCCC(F)(F)F)cc2F)(C(F)(F)F)CC(c2ccn(C3CC3)n2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3915598 IC50 81.0 nM
Cc1ccc(C2=C(NC(=O)c3oncc3C)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3895643 IC50 84.0 nM
COc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(C#CCCc3ccccc3)(C(F)(F)F)C2)cc1 CHEMBL3924889 IC50 84.0 nM
Cc1ccc(C2=C(C(=O)NS(=O)(=O)c3ccccc3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3902204 IC50 84.0 nM
O=C1N[C@@](c2cnn(CC/C=C/CCC(F)(F)F)c2)(C(F)(F)F)CC(c2ccc3c(c2)CCCC3)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3935544 IC50 88.0 nM
COCc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3902194 IC50 89.0 nM
CCn1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3ccc(CCCCC(F)(F)F)cc3F)(C(F)(F)F)C2)n1 CHEMBL3970221 IC50 89.0 nM
CCCCOc1ccc(C2(C)CC(c3ccc(C)cc3)=C(C#N)C(=O)N2)cc1 CHEMBL3922576 IC50 93.0 nM
CCOc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCCCC(F)(F)F)c(F)c3)(C(F)(F)F)C2)cc1 CHEMBL3895568 IC50 94.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccc(F)cc3)C(=O)NC(c3ccc(-c4cnccn4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3892481 IC50 95.0 nM
COc1cc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)ccc1C CHEMBL3898538 IC50 96.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc3c(c2)OCO3)=C1c1nn[nH]n1 CHEMBL3898104 IC50 97.0 nM
O=C1N[C@@](c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccn(C3CC3)n2)=C1C(=O)NS(=O)(=O)C1CC1 CHEMBL3910604 IC50 98.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccc(F)cc3)C(=O)NC(c3ccc(Oc4ncccn4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3901434 IC50 99.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(C(C)(C)C)cc3)(C(F)(F)F)C2)cc1 CHEMBL3916974 IC50 100.0 nM
CCCCCCCNC(=O)C1(C)CC(c2ccc(C)cc2)=C(C(=O)Nc2ccc(OC)cc2)C(=O)N1 CHEMBL3910387 IC50 102.0 nM
Cc1ccc(C2=C(N)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3938073 IC50 103.0 nM
CCOc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1Cl CHEMBL3972459 IC50 103.0 nM
CCCOc1ccc(C2(C(F)(F)F)CC(c3ccc(C)cc3)=C(NC(=O)CS(C)(=O)=O)C(=O)N2)cc1 CHEMBL3913378 IC50 105.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(Cl)cc2)=C1c1nn[nH]n1 CHEMBL3911572 IC50 108.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)c(C)c3)(C(F)(F)F)C2)cc1 CHEMBL3890106 IC50 109.0 nM
Cc1ccc(C2=C(c3nnn[nH]3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)c(C)c3)(C(F)(F)F)C2)cc1 CHEMBL4854441 IC50 109.0 nM
COc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1Cl CHEMBL3977205 IC50 112.0 nM
Cc1ccc(C2=C(NC(=O)c3ccccc3Cl)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3897775 IC50 113.0 nM
Cc1ccc(C2=C(C(=O)NS(C)(=O)=O)C(=O)N[C@](C)(CCC(C)C)C2)cc1 CHEMBL4107292 IC50 114.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1C CHEMBL3949041 IC50 118.0 nM
CS(=O)(=O)NC(=O)C1=C(c2ccn(C3CC3)n2)C[C@](c2ccc(OCCCCCC(F)(F)F)cc2F)(C(F)(F)F)NC1=O CHEMBL3910055 IC50 119.0 nM
CCn1nnc(C2=C(c3ccc(C)cc3)CC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)n1 CHEMBL2441599 IC50 121.0 nM
Cc1ccc(C2=C(NC(=O)c3cc(-c4ccccc4Cl)no3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3934531 IC50 121.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCOC(C)(C)C)cc3)(C(F)(F)F)C2)cc1 CHEMBL3915290 IC50 126.0 nM
COc1ccc(NC(=O)C2=C(c3ccc(C)cc3)C(F)(F)C(c3ccc(OCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cc1 CHEMBL3967703 IC50 127.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(Oc4ccccc4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3893559 IC50 127.0 nM
COc1ccc(NS(=O)(=O)c2ccc(OCCc3ccccc3)c(NC(C)=O)c2)cc1 CHEMBL3581738 IC50 130.0 nM
COc1ccc(NS(=O)(=O)c2ccc(C)c(NC(=O)COc3ccccc3)c2)cc1 CHEMBL3581737 IC50 130.0 nM
CNc1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(CCc1ccccc1)CC2 CHEMBL3581726 IC50 130.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc3c(c2)CCO3)=C1c1nn[nH]n1 CHEMBL3909786 IC50 130.0 nM
Cc1ccc(C2=C(c3nnc(C(F)(F)F)o3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3970305 IC50 138.0 nM
Cc1cc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)ccc1Cl CHEMBL3963027 IC50 152.0 nM
Cc1ccc(C2=C(NC(=O)c3cc(-c4cccc(F)c4)no3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3985668 IC50 155.0 nM
COc1ccc(C(=O)NC2=C(c3ccc(C)cc3)C(F)(F)C(c3ccc(OCCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cc1 CHEMBL3965170 IC50 162.0 nM
Cc1ccc(C2=C(C(=O)Nn3cnc([N+](=O)[O-])n3)C(=O)NC(c3ccc(OCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3948070 IC50 163.0 nM
COc1ccc(-c2ccc(C3(C(F)(F)F)CC(c4ccc(C)cc4)=C(C#N)C(=O)N3)cc2)cc1 CHEMBL3910641 IC50 164.0 nM
COc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1F CHEMBL3986380 IC50 166.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccc(-c4nn[nH]n4)cc3)C(=O)NC(c3ccc(OCCC(F)(F)F)cc3)(C(F)(F)F)C2(F)F)cc1 CHEMBL3909765 IC50 168.0 nM
CC(=O)Nc1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2ncn(CCc3ccc(F)cc3)c12 CHEMBL3581720 IC50 170.0 nM
CCNC(=O)NC1=C(c2ccc(OCC(F)F)cc2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3957294 IC50 170.0 nM
CCCCCC1(C)CC(c2ccc(C)cc2)=C(C#N)C(=O)N1 CHEMBL4868511 IC50 175.0 nM
Cc1ccc(C2=C(c3cn[nH]n3)C(=O)NC(C#CC3CC3)(C(F)(F)F)C2)cc1 CHEMBL3929197 IC50 178.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(C#CC4CCCCC4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3947233 IC50 178.0 nM
Cc1ccc(C2=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N[C@@](c3cnn(CCCCCC(F)(F)F)c3)(C(F)(F)F)C2)cc1 CHEMBL3941048 IC50 179.0 nM
COc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(C#CCCC(C)C)(C(F)(F)F)C2)cc1 CHEMBL3926001 IC50 183.0 nM
Cc1ccc(C2=C(NC(=O)c3ccccc3F)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3964314 IC50 185.0 nM
CCCCCCc1cnc(C2(C)CC(c3ccc(C)cc3)=C(C#N)C(=O)N2)o1 CHEMBL3951482 IC50 189.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(Br)cc3)(C(F)(F)F)C2)cc1 CHEMBL3930301 IC50 204.0 nM
N#CC1=C(c2ccc(C(F)(F)F)cc2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3967669 IC50 209.0 nM
Cc1ccc(C2=C(NC(=O)c3ccc(F)cc3Cl)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3928776 IC50 210.0 nM
N#CC1=C(c2ccc(Cl)cc2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3961584 IC50 214.0 nM
COc1ccc(C(=O)NC2=C(c3ccc(C)cc3)C(F)(F)C(c3ccc(OCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cc1 CHEMBL3949100 IC50 214.0 nM
Cc1ccc(NC(=O)C2=C(c3ccc(C)cc3)CC(c3ccc(OCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cc1 CHEMBL3926326 IC50 222.0 nM
Cc1ccc(C2=C(n3cnnc3C)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3972581 IC50 229.0 nM
N#CC1=C(c2ccc(C#N)cc2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3984215 IC50 231.0 nM
CCCCCCCc1cnc([C@@]2(C(F)(F)F)CC(c3ccc(C)cc3)=C(C(=O)NS(=O)(=O)C3CC3)C(=O)N2)s1 CHEMBL4107800 IC50 235.0 nM
CC(=O)C(=O)NC1=C(c2ccc(C)cc2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3931508 IC50 243.0 nM
Cc1ccc(C2=C(NC(=O)c3cnccn3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3973406 IC50 247.0 nM
CCC1(CC)NCc2cc(S(=O)(=O)Nc3ccc(F)cc3F)ccc2NC1=O CHEMBL2376314 pIC50 251.19 nM
Cc1ccc(C2=C(C(=O)Nc3ccccc3OC(F)(F)F)C(=O)NC(c3ccc(OCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3922078 IC50 252.0 nM
Cc1ccc(C2=C(NC(=O)c3cnco3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3921377 IC50 252.0 nM
N#CC1=C(c2ccc(F)cc2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3964365 IC50 253.0 nM
Cc1ccc(C2=C(c3nnn[nH]3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)c(C)c1 CHEMBL3940319 IC50 254.0 nM
Cc1ccc(C2=C(c3nnn[nH]3)C(=O)N[C@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL4114461 IC50 261.0 nM
COc1ccc(NC(=O)C2=C(c3ccc(C)cc3)CC(C)(C(=O)NCCCc3ccccc3)NC2=O)cc1 CHEMBL3927024 IC50 264.0 nM
O=S(=O)(Nc1ccc(F)cc1F)c1ccc2c(c1)CCN2CCc1ccccc1 CHEMBL3581725 IC50 270.0 nM
C[C@@H](NS(C)(=O)=O)c1ccc(CN2CCO[C@@H](c3ccc(F)cc3)C2)cc1 CHEMBL3699813 IC50 274.0 nM
COc1cccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)c1 CHEMBL3926278 IC50 280.0 nM
Cc1ccc(C2=C(C(=O)Nc3nn[nH]n3)C(=O)NC(c3ccc(OCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3930198 IC50 282.0 nM
COc1ccc(C2=C(C(=O)NS(C)(=O)=O)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3972533 IC50 295.0 nM
CCCCCCCc1cnc(C2(C(F)(F)F)CC(c3ccc(C)cc3)=C(c3nn[nH]n3)C(=O)N2)s1 CHEMBL3919451 IC50 304.0 nM
CCC1(CC)CNc2ccc(S(=O)(=O)Nc3ccc(F)cc3F)cc2CN1 CHEMBL2376315 pIC50 316.23 nM
Cc1ccc(C2=C(C(=O)Nc3cccc(C)c3)C(=O)NC(c3ccc(OCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3938442 IC50 328.0 nM
Cc1ccc(C2=C(C(=O)Nc3nnc(C(F)(F)F)o3)C(=O)NC(c3ccc(OCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3944534 IC50 328.0 nM
Cc1ccc(C2=C(C(=O)NS(=O)(=O)C(C)(C)C)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3928086 IC50 348.0 nM
COc1ccc(C2=C(C(=O)NS(=O)(=O)N(C)C)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3933277 IC50 353.0 nM
COc1ccc(C2=C(c3ccc(C)cc3)C(F)(F)C(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cn1 CHEMBL3943591 IC50 356.0 nM
Cc1cccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)c1 CHEMBL4864008 IC50 370.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3cnn(CCCCC(F)(F)F)c3)(C(F)(F)F)C2)cc1 CHEMBL3982452 IC50 374.0 nM
CCC1(C)NC(=O)c2cc(S(=O)(=O)Nc3ccc(Cl)cc3)ccc2N(C)C1=O CHEMBL2376312 pIC50 398.11 nM
CCC1(C)NC(=O)c2cc(S(=O)(=O)Nc3ccccc3)ccc2NC1=O CHEMBL2376322 pIC50 398.11 nM
CCCCCCCCNC(=O)C1(C)CC(c2ccc(C)cc2)=C(C#N)C(=O)N1 CHEMBL3942300 IC50 399.0 nM
COc1cccc(-c2ccc(CNC(=O)[C@@H]3C[C@H]3c3ccccc3)c3ncccc23)c1 CHEMBL3736366 IC50 400.0 nM
Cc1ccc(C2=C(NC(=O)[C@@H](C)O)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL4115039 IC50 411.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(C)cc3)(C(F)(F)F)C2)cc1 CHEMBL3946366 IC50 415.0 nM
COc1ccc(NC(=O)C2C(=O)N[C@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)CC2c2ccc(C)cc2)cc1 CHEMBL4112192 IC50 416.0 nM
COc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)c2c1CCC2 CHEMBL3958228 IC50 416.0 nM
Cc1ccc(C2=C(NC(=O)c3cccc(Cl)c3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3925862 IC50 421.0 nM
COOCNc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3941018 IC50 421.0 nM
Cc1ccc(C2=C(NC(=O)n3ncnn3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3928508 IC50 433.0 nM
Cc1ccc(C2=C(n3ncnn3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL5411387 IC50 433.0 nM
COc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1OC CHEMBL3978174 IC50 440.0 nM
Cc1ccc(C2=C(C(=O)NC3CCCC3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2(F)F)cc1 CHEMBL3958506 IC50 459.0 nM
CCCCCCNC(=O)c1ccc(C2(C(F)(F)F)CC(c3ccc(C)cc3)=C(C(=O)Nc3ccc(OC)cc3)C(=O)N2)cc1 CHEMBL3902478 IC50 484.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc(-n3cccn3)cc2)=C1c1nn[nH]n1 CHEMBL3913095 IC50 489.0 nM
Cc1ccc(C2=C(Oc3ccccc3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3946881 IC50 552.0 nM
COc1ccccc1C1(C(F)(F)F)CC(c2ccc(C)cc2)=C(C#N)C(=O)N1 CHEMBL4846863 IC50 556.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(C)(c3ccc(C)cc3)C2)cc1 CHEMBL4879045 IC50 593.0 nM
Cc1ccc(C2=C(NC(=O)CNS(C)(=O)=O)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3964250 IC50 639.0 nM
Cc1ccc(C2=C(C(=O)Nc3ccc(C#N)cc3)C(=O)NC(C3CCC(OCCCC(F)(F)F)CC3)(C(F)(F)F)C2(F)F)cc1 CHEMBL3905911 IC50 645.0 nM
CCCCCC1(C)C=C(c2ccc(C)cc2)C(C#N)C(=O)N1 CHEMBL3899052 IC50 651.0 nM
CCNC(=O)NC1=C(c2ccc(C)cc2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3945101 IC50 702.0 nM
Cc1ccc(C2=C(n3ccnc3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3890851 IC50 704.0 nM
Cc1ccc(C2=C(n3ccnc3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL5412270 IC50 704.0 nM
Cc1ccc(C2=C(C(=O)Nc3cccc(Cl)c3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3897196 IC50 709.0 nM
N#CC1=C(c2ccc(Cl)c(Cl)c2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3903039 IC50 733.0 nM
COc1ccc(C2=C[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)NC(=O)C2(F)C#N)cc1 CHEMBL4108979 IC50 756.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCc4ccccc4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3902531 IC50 756.0 nM
COc1cccc(-c2ccc(CNC(=O)Nc3cccc(Cl)c3Cl)c3cnccc23)c1 CHEMBL3736092 IC50 760.0 nM
Cc1ccc(NC(=O)C2=C(c3ccc(C)cc3)C(F)(F)C(c3ccc(OCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cc1 CHEMBL3916598 IC50 778.0 nM
O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2cccc(Cl)c2)=C1c1nn[nH]n1 CHEMBL3964017 IC50 795.0 nM
Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3cccc(OCCCC(F)(F)F)c3)(C(F)(F)F)C2)cc1 CHEMBL3925930 IC50 796.0 nM
CCCCCCC(=O)CNC(=O)C1(C)CC(c2ccc(C)cc2)=C(NC(=O)c2ccc(OC)cc2)C(=O)N1 CHEMBL3915919 IC50 797.0 nM
COc1cccc(-c2ccc(CNC(=O)[C@@H]3C[C@H]3c3ccccc3)c3cnccc23)c1 CHEMBL3734770 IC50 800.0 nM
CCOc1ccc(-c2ccc(C3(C(F)(F)F)CC(c4ccc(C)cc4)=C(C#N)C(=O)N3)cc2)cn1 CHEMBL3955834 IC50 818.0 nM
Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(Oc4ncccn4)cc3)(C(F)(F)F)C2)cc1 CHEMBL3970154 IC50 871.0 nM
COOSNc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL3985290 IC50 889.0 nM
Cc1ccc(C2=C(c3nnn[nH]3)C(=O)NC(C)(c3ccc(C)cc3)C2)cc1 CHEMBL3926254 IC50 913.0 nM
N#CC1=C(c2cccc(C#N)c2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O CHEMBL3912704 IC50 983.0 nM