N#Cc1ccc(Nc2ncnc3ccc(-c4ccc(C(=O)N5CCNCC5)cc4)nc23)cc1 CHEMBL4879010 IC50 0.15 nM
O=C1NC2(CCCCC2)n2c1c(Cl)cc(Nc1cc(NC(=O)C3CC3)ncn1)c2=O CHEMBL4073743 IC50 0.51 nM
Nc1cc(Nc2cc(Cl)c3n(c2=O)C2(CCCCC2)NC3=O)ncn1 CHEMBL4076439 IC50 0.65 nM
Nc1cc(Nc2cc(Cl)c3n(c2=O)C2(CCCC2)NC3=O)ncn1 CHEMBL4094975 IC50 0.88 nM
COc1cc2[nH]ncc2cc1Nc1ncnc2[nH]c3c(c12)CC(C(=O)NCc1ccccc1)CC3 CHEMBL3355000 IC50 1.0 nM
CC(C)Oc1cc2[nH]ncc2cc1Nc1ncnc2[nH]c3c(c12)CC(C(=O)NCCCS(C)(=O)=O)CC3 CHEMBL3355002 IC50 1.0 nM
COc1cc(Nc2ncnc3ccc(-c4ccc(C(=O)N5CCNCC5)cc4)nc23)ccc1F CHEMBL4859971 IC50 1.0 nM
CC(C)Oc1cc(F)ccc1Nc1ncnc2ccc(-c3ccc(C(=O)N4CCNCC4)cc3)nc12 CHEMBL4869634 IC50 1.0 nM
COc1cc2[nH]ncc2cc1Nc1ccnc2[nH]c(S(=O)(=O)c3ccc(C)cc3)cc12 CHEMBL5201681 IC50 1.0 nM
COc1cc2[nH]c(=O)sc2cc1Nc1ncnc2[nH]cc(F)c12 CHEMBL5174006 IC50 1.0 nM
O=C(c1ccc(-c2ccc3ncnc(Nc4ccc(F)cc4)c3n2)cc1)N1CCNCC1 CHEMBL4876307 IC50 1.1 nM
COc1cc(F)ccc1Nc1ncnc2ccc(-c3ccc(C(=O)N4CCNCC4)cc3)nc12 CHEMBL4857156 IC50 1.2 nM
Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21CCC(F)(F)CC1 CHEMBL4065802 IC50 1.4 nM
C[C@H]1CN(c2cccc3nc(-c4nc(-c5cccc(C(=O)N(C)C)c5)cnc4N)n(C)c23)CCN1 CHEMBL3797873 IC50 1.5 nM
N[C@H]1C[C@H](Oc2ccc3ncc(-c4ccc5cnccc5c4)n3n2)C1 CHEMBL4094080 IC50 1.5 nM
CC1(c2cccc(Cl)c2)NC(=O)c2c(Cl)cc(Nc3cc(NC(=O)C4CC4)ncn3)c(=O)n21 CHEMBL4064839 IC50 1.6 nM
O=C1NCc2cc(Nc3cc(NC(=O)C4CC4)ncn3)ccc21 CHEMBL4100554 IC50 1.9 nM
CN(C)C(=O)c1cccc(-c2cnc(N)c(-c3nc4cccc(N5CCNCC5)c4n3C)n2)c1 CHEMBL3798762 IC50 2.0 nM
COc1cccc2oc(-c3cnc4ccc(OCCC[S+](C)[O-])nn34)cc12 CHEMBL3904937 IC50 2.0 nM
COc1cccc2oc(-c3cnc4ccc(OCCCS(C)(=O)=O)nn34)cc12 CHEMBL3940077 IC50 2.0 nM
COc1cccc2oc(-c3cnc4ccc(OCCCS(C)(=N)=O)nn34)cc12 CHEMBL3930574 IC50 2.0 nM
Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21CCCCC1 CHEMBL4298140 IC50 2.0 nM
O=C1NC2(CCCCC2)n2c1c(Cl)cc(Nc1ccncn1)c2=O CHEMBL4439094 Ki 2.0 nM
CC1(C)NC(=O)c2c(Cl)cc(Nc3cc(N)ncn3)c(=O)n21 CHEMBL4067557 IC50 2.2 nM
N[C@H]1CCCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc6cnccc6c5)n4n3)cc2)C1 CHEMBL4878199 IC50 2.3 nM
Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21CCCCC1 CHEMBL4073443 IC50 2.4 nM
O=C(c1ccc(-c2ccc3ncc(-c4ccc5cnccc5c4)n3c2)cc1)N1CCC(N2CCCCC2)CC1 CHEMBL4858035 IC50 2.4 nM
N[C@H]1CCCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc6cnccc6c5)n4c3)cc2)C1 CHEMBL4857770 IC50 2.5 nM
CN(C)CCCNC(=O)c1nc2c(N3CCc4cc(F)ccc43)ncnc2s1 CHEMBL5181488 pIC50 2.512 nM
CC1(C)NC(=O)c2ccc(Nc3cc(NC(=O)C4CC4)ncn3)c(=O)n21 CHEMBL4086319 IC50 2.7 nM
C[C@H]1CN(c2cccc3nc(-c4nc(-c5cc(C(=O)N(C)C)ccn5)cnc4N)n(C)c23)CCN1 CHEMBL3800585 IC50 3.0 nM
CC1(C)CN(c2ncnc3sc(C(=O)NCC4CCNCC4)nc23)c2ccccc21 CHEMBL5183975 pIC50 3.162 nM
O=C(NCC1CCNCC1)c1nc2c(N3CCc4cc(Cl)ccc43)ncnc2s1 CHEMBL5180948 pIC50 3.162 nM
CC1(C)NC(=O)c2c(Cl)cc(Nc3ccncn3)c(=O)n21 CHEMBL4084102 IC50 3.3 nM
CN(C)C(=O)c1cccc(-c2cnc(N)c(-c3nc4cccc(N5CCNCC5)c4[nH]3)c2)c1 CHEMBL3797828 IC50 4.0 nM
C[S+]([O-])CCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 CHEMBL3932933 IC50 4.0 nM
CS(=N)(=O)CCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 CHEMBL3925147 IC50 4.0 nM
O=C(c1ccc(-c2ccc3ncc(-c4ccc5cnccc5c4)n3c2)cc1)N1CCC(N2CCOCC2)CC1 CHEMBL4864827 IC50 4.0 nM
Nc1n[nH]c2cc(-c3ccc(=O)n(Cc4cccc(Cl)c4)c3)cc(NCC3CCOCC3)c12 CHEMBL5196282 IC50 4.0 nM
CC(C)Oc1cc2[nH]ncc2cc1Nc1ncnc2[nH]c3c(c12)CCCC3 CHEMBL3354998 IC50 5.0 nM
C[S+]([O-])CCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 CHEMBL3910498 IC50 5.0 nM
CS(=O)(=O)CCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 CHEMBL3983678 IC50 5.0 nM
COc1ccc2oc(-c3cnc4ccc(OCCCS(C)(=O)=O)nn34)cc2c1 CHEMBL3913844 IC50 5.0 nM
CC(=O)N1CCC(CNc2cc(-c3ccc(=O)n(Cc4cccc(Cl)c4)c3)cc3[nH]nc(N)c23)CC1 CHEMBL5204789 IC50 5.0 nM
O=C(NCC1CCNCC1)c1nc2c(N3CCc4cc(F)ccc43)ncnc2s1 CHEMBL5203720 pIC50 5.012 nM
COc1cc(Cl)c(Cl)cc1Nc1ncnc2[nH]c3c(c12)CC(C(=O)NC1CC1)CC3 CHEMBL3354997 IC50 6.0 nM
CCNC(=O)C1CCc2[nH]c3ncnc(Nc4cc5cn[nH]c5cc4OC)c3c2C1 CHEMBL3354999 IC50 6.0 nM
Nc1n[nH]c2cc(-c3ccc(=O)n(Cc4cccc(Cl)c4)c3)cc(OCC3CCOCC3)c12 CHEMBL5176495 IC50 6.0 nM
CN(C)CCCNC(=O)c1nc2c(N3CC(C)(C)c4ccccc43)ncnc2s1 CHEMBL5206647 pIC50 6.31 nM
CC1(C)NC(=O)c2c(F)cc(Nc3ccncn3)c(=O)n21 CHEMBL4091862 IC50 6.5 nM
CS(=O)(=O)CCCOc1ccc2ncc(-c3cc4cc(F)ccc4o3)n2n1 CHEMBL3908576 IC50 7.0 nM
CS(=O)(CCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1)=NC#N CHEMBL3971422 IC50 7.0 nM
Cc1cc(Nc2cc(N3CCN(CCCN(C)C)CC3)ncn2)c(=O)n2c1C(=O)NC21CCCCC1 CHEMBL4757546 IC50 7.0 nM
O=C(c1ccc(-c2ccc3ncc(-c4ccc5cnccc5c4)n3c2)cc1)N1CCOCC1 CHEMBL4869957 IC50 7.0 nM
Cc1ccc(C(=O)Nc2ccc(Oc3cc4cnn(C)c4cc3-c3cn[nH]c3)c(F)c2)c(=O)n1-c1ccc(F)cc1 CHEMBL3545307 IC50 7.0 nM
N[C@@H]1CCCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc6cnccc6c5)n4c3)cc2)C1 CHEMBL4852274 IC50 7.7 nM
CS(=N)(=O)CCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 CHEMBL3977764 IC50 8.0 nM
O=C(c1ccc(-c2ccc3ncnc(Nc4ccc(O)cc4)c3n2)cc1)N1CCNCC1 CHEMBL4861251 IC50 8.5 nM
Cc1cc(Nc2cc(N3CCN(CCN(C)C)CC3)ncn2)c(=O)n2c1C(=O)NC21CCCCC1 CHEMBL4796087 IC50 8.7 nM
COc1cccc2oc(-c3cnc4ccc(OCCCS(C)(=O)=NC(=O)C(F)(F)F)nn34)cc12 CHEMBL3902586 IC50 9.0 nM
COc1nccc2oc(-c3cnc4ccc(OCCCS(C)(=O)=NC#N)nn34)cc12 CHEMBL3941832 IC50 9.0 nM
COc1nccc2oc(-c3cnc4ccc(OCCCS(C)(=N)=O)nn34)cc12 CHEMBL3979535 IC50 9.0 nM
CN(C)C1CCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc(C#N)cc5)n4n3)cc2)CC1 CHEMBL4216109 IC50 9.0 nM
O=C(c1ccc(-c2ccc3ncc(-c4ccc5cnccc5c4)n3c2)cc1)N1CCNCC1 CHEMBL4865340 IC50 9.4 nM
N[C@@H]1CCCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc6cnccc6c5)n4n3)cc2)C1 CHEMBL4862069 IC50 9.4 nM
C[S+]([O-])CCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 CHEMBL3941910 IC50 10.0 nM
Cc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC2(C)C CHEMBL4062387 IC50 10.0 nM
CN(C)CCCNC(=O)c1nc2c(N3CCc4ccccc43)ncnc2s1 CHEMBL5171562 pIC50 10.0 nM
N#Cc1ccc(-c2cnc3sc(-c4ccc(C(=O)NCCN5CCCC5)cc4)nn23)cc1 CHEMBL5280197 IC50 10.02 nM
Cc1cc(Nc2ccncn2)c(=O)n2c1C(=O)NC21CCCCC1 CHEMBL4780209 IC50 10.5 nM
N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)N5CCOCC5)cc4)cn23)cc1 CHEMBL4211649 IC50 10.6 nM
Nc1n[nH]c2cc(-c3ccc(=O)n(Cc4cccc(Cl)c4)c3)ccc12 CHEMBL4764756 IC50 10.8 nM
c1cc(-c2cnn3cc(-c4ccc(OCCN5CCCCC5)cc4)cnc23)ccn1 CHEMBL478629 IC50 11.0 nM
COc1nccc2oc(-c3cnc4ccc(OC[C@H]5CNCCO5)nn34)cc12 CHEMBL4113364 IC50 11.0 nM
CSCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 CHEMBL3947209 IC50 11.0 nM
Cc1cc2ncc(-c3cc4ccccc4o3)n2nc1OCCCS(C)(=O)=O CHEMBL3917524 IC50 11.0 nM
CN1CCN(C(=O)c2ccc(-c3nn4c(-c5ccc(C#N)cc5)cnc4s3)cc2)CC1 CHEMBL5271233 IC50 11.5 nM
COc1nccc2oc(-c3cnc4ccc(OCCCS(C)(=O)=O)nn34)cc12 CHEMBL3942067 IC50 12.0 nM
Nc1n[nH]c2cc(-c3ccc(=O)n(Cc4ccccc4F)c3)ccc12 CHEMBL4752141 IC50 12.0 nM
CN(C)CCCNC(=O)c1cc2ncnc(N3CCc4cc(F)ccc43)c2n1C CHEMBL5196084 pIC50 12.59 nM
CS(=O)(CCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1)=NC(=O)C(F)(F)F CHEMBL3893616 IC50 13.0 nM
N#Cc1ccc(-c2cnc3sc(-c4ccc(C(=O)NCCO)cc4)nn23)cc1 CHEMBL5286963 IC50 13.58 nM
C[C@@H](Oc1cc(F)ccc1Nc1ncnc2cc(N=S3(=O)CCC3)cc(F)c12)C(=O)NCC(F)(F)F CHEMBL4107950 IC50 14.0 nM
Cc1n[nH]c(C)c1-c1cncc(-c2ccc(C(N)=O)c(OC(C)C)c2)c1 CHEMBL4442209 IC50 14.0 nM
NC1CCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc6cnccc6c5)n4n3)cc2)CC1 CHEMBL4862651 IC50 14.5 nM
CS(=O)(=O)CCCOc1ccc2ncc(-c3cc4cc(Cl)ccc4o3)n2n1 CHEMBL3931048 IC50 15.0 nM
CS(=O)(CCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1)=NC(=O)C(F)(F)F CHEMBL3916135 IC50 15.0 nM
CSCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 CHEMBL3963801 IC50 16.0 nM
N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)N5CCNCC5)cc4)nn23)cc1 CHEMBL4208772 IC50 16.0 nM
NC1CCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc6cnccc6c5)n4c3)cc2)CC1 CHEMBL4872637 IC50 16.8 nM
CS(=O)(=O)CCCOc1ccc2ncc(-c3cc4c(F)cccc4o3)n2n1 CHEMBL3945413 IC50 17.0 nM
CS(=O)(=O)CCCOc1nn2c(-c3cc4ccccc4o3)cnc2cc1-c1ccccc1 CHEMBL3974882 IC50 17.0 nM
Nc1n[nH]c2cc(-c3ccc(=O)n(Cc4cccc(F)c4)c3)ccc12 CHEMBL4787269 IC50 19.0 nM
CN1CCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc(C#N)cc5)n4n3)cc2)CC1 CHEMBL4213168 IC50 20.0 nM
Cc1cc(Nc2cc(N3CCNCC3)ncn2)c(=O)n2c1C(=O)NC21CCCCC1 CHEMBL4754824 IC50 20.7 nM
C[C@H](NC(=O)[C@@H](C)Oc1cc(F)ccc1Nc1ncnc2cc(N=S(C)(C)=O)cc(F)c12)C(F)(F)F CHEMBL4110890 IC50 21.0 nM
COc1cccc2oc(-c3cnc4ccc(OCCCSC)nn34)cc12 CHEMBL3919421 IC50 21.0 nM
CN1CCC(C(=O)Nc2ncc(-c3ccccc3)s2)CC1 CHEMBL5181172 IC50 21.0 nM
N#Cc1ccc(-c2cnc3sc(-c4ccc(C(=O)NCCCO)cc4)nn23)cc1 CHEMBL5288682 IC50 21.6 nM
O=C1NCc2cc(Nc3ncnc4[nH]cnc34)ccc21 CHEMBL4077341 IC50 23.0 nM
N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)N5CCOCC5)cc4)nn23)cc1 CHEMBL4203889 IC50 23.0 nM
Cc1c(C(=O)NCCCN(C)C)sc2ncnc(Nc3ccc(F)cc3OC(C)CF)c12 CHEMBL3702341 IC50 23.0 nM
Cc1cc([C@@H](C)Oc2cc(F)ccc2Nc2ncnc3cc(N=S(C)(C)=O)cc(C)c23)on1 CHEMBL4112682 IC50 25.0 nM
CN(C)CCNC(=O)c1ccc(-c2nn3c(-c4ccc(C#N)cc4)cnc3s2)cc1 CHEMBL5278124 IC50 25.04 nM
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CHEMBL574738 Kd 26.0 nM
c1cc(-c2cnc3c(-c4cn[nH]c4)cnn3c2)ccc1OCCN1CCOCC1 CHEMBL1271532 IC50 27.0 nM
C[C@@H](Oc1cc(F)ccc1Nc1ncnc2cc(N=S3(=O)CCC3)cc(Cl)c12)C(=O)NCC(F)(F)F CHEMBL4115007 IC50 27.0 nM
CSCCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 CHEMBL3959489 IC50 27.0 nM
N[C@H]1CCCN(C(=O)c2ccc(-c3cn4c(-c5ccc6cnccc6c5)cnc4cn3)cc2)C1 CHEMBL4865426 IC50 27.3 nM
N#Cc1ccc(-c2cnc3sc(-c4ccc(C(=O)N5CCCC5)cc4)nn23)cc1 CHEMBL5288290 IC50 27.8 nM
CS(=O)(=O)CCCOc1ccc2ncc(-c3cc4cnccc4o3)n2n1 CHEMBL3915020 IC50 28.0 nM
CC1NC(=O)c2ccc(Nc3ccncn3)cc21 CHEMBL4099497 IC50 28.0 nM
C[C@H](NC(=O)[C@@H](C)Oc1cc(F)ccc1Nc1ncnc2cc(N=S3(=O)CCC3)cc(F)c12)C(F)(F)F CHEMBL4112904 IC50 29.0 nM
COc1nccc2oc(-c3cnc4ccc(OCC5CNC5)nn34)cc12 CHEMBL3901529 IC50 31.0 nM
N#Cc1ccc(-c2cnc3sc(-c4ccc(C(=O)NCCCN5CCOCC5)cc4)nn23)cc1 CHEMBL5270526 IC50 31.13 nM
CN[C@H](C)COc1ccc2ncc(-c3cc4c(OC)nccc4o3)n2n1 CHEMBL4110114 IC50 32.0 nM
O=C1NC2(CCCCC2)n2c1c(Cl)cc(Nc1ccncc1)c2=O CHEMBL4449736 Ki 32.0 nM
NC1CCN(C(=O)c2ccc(-c3cn4c(-c5ccc6cnccc6c5)cnc4cn3)cc2)CC1 CHEMBL4857509 IC50 32.1 nM
Cc1cc(N=S2(=O)CCCC2)cc2ncnc(Nc3ccc(F)cc3OC(CF)CF)c12 CHEMBL3982761 IC50 34.0 nM
Cc1cc([C@@H](C)Oc2ncccc2Nc2ncnc3cc(N=S(C)(C)=O)cc(C)c23)on1 CHEMBL4111586 IC50 34.0 nM
Cc1c(C(=O)NCCCN(C)C)sc2ncnc(Nc3ccc(F)cc3OC(C)C)c12 CHEMBL3659491 IC50 35.0 nM
CN(C)C(=O)c1cccc(-c2cnc(N)c(-c3nc4ccccc4[nH]3)c2)c1 CHEMBL3797574 IC50 36.0 nM
Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(Cl)cc3O[C@H](C)C(=O)N[C@@H](C)C(F)(F)F)c12 CHEMBL4115037 IC50 36.0 nM
CC1CCCCN1C(=O)c1ccc(-c2nn3c(-c4ccc(C#N)cc4)cnc3s2)cc1 CHEMBL5279032 IC50 36.91 nM
O=c1ccc(-c2ccc3cn[nH]c3c2)cn1Cc1cccc(Cl)c1 CHEMBL4749973 IC50 37.0 nM
Cc1cc(N=S2(=O)CCCC2)cc2ncnc(Nc3ccc(F)cc3O[C@H](C)C(=O)NCC(F)(F)F)c12 CHEMBL4109890 IC50 38.0 nM
CCNC(=O)N1CCS(=O)(=Nc2cc(C)c3c(Nc4ccc(F)cc4O[C@H](C)c4cc(C)no4)ncnc3c2)CC1 CHEMBL4108901 IC50 39.0 nM
CC(C)Oc1cc(F)ccc1Nc1ncnc2cc(C(=O)NCC3CCNCC3)n(C)c12 CHEMBL5203734 pIC50 39.81 nM
Fc1ccc2c(c1)CCN2c1ncnc2cc[nH]c12 CHEMBL5183411 pIC50 39.81 nM
Cc1cc(N=S2(=O)CCCC2)cc2ncnc(Nc3ccc(F)cc3O[C@H](C)C(F)(F)F)c12 CHEMBL4106460 IC50 40.0 nM
Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3O[C@H](C)C(F)(F)F)c12 CHEMBL4112179 IC50 40.0 nM
O=c1ccc(-c2ccc3cn[nH]c3c2)cn1Cc1cccc(C(F)(F)F)c1 CHEMBL4746396 IC50 40.0 nM
CC(=O)NC[C@@H](C)Oc1ccc2ncc(-c3cc4ccc(O)cc4o3)n2n1 CHEMBL5182166 IC50 40.0 nM
C[C@H](CN)Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1 CHEMBL5207564 IC50 40.0 nM
N[C@@H]1CCCN(C(=O)c2ccc(-c3cn4c(-c5ccc6cnccc6c5)cnc4cn3)cc2)C1 CHEMBL4879113 IC50 42.0 nM
N#Cc1ccc(-c2cnc3sc(-c4ccc(C(=O)NCCCCCO)cc4)nn23)cc1 CHEMBL5288098 IC50 42.93 nM
CC(=O)C1=C(O)C=C2Oc3c(C(N)=O)c(O)cc(O)c3[C@]2(C)C1=O CHEMBL475816 IC50 43.0 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 44.17 nM
O=c1ccc(-c2cnn3cc(-c4ccc(OCCN5CCOCC5)cc4)cnc23)c[nH]1 CHEMBL1271480 IC50 45.0 nM
CS(=O)(CCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1)=NC(=O)C(F)(F)F CHEMBL3903632 IC50 47.0 nM
O=c1ccc(-c2ccc3cn[nH]c3c2)cn1Cc1ccccc1F CHEMBL4795993 IC50 47.0 nM
COc1nccc2oc(-c3cnc4ccc(OCC5CCCCN5)nn34)cc12 CHEMBL3933505 IC50 48.0 nM
CS(=O)(=O)CCCOc1ccc2ncc(-c3cc4cccc(F)c4o3)n2n1 CHEMBL3903071 IC50 48.0 nM
Cc1cc([C@@H](C)Oc2ncccc2Nc2ncnc3cc(N=S4(=O)CCCC4)cc(C)c23)on1 CHEMBL4112720 IC50 49.0 nM
Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3O[C@H](C)C#N)c12 CHEMBL4113835 IC50 50.0 nM
CC(C)Oc1cc(F)ccc1Nc1ncnc2cc(C(=O)NCCCN(C)C)n(C)c12 CHEMBL5186068 pIC50 50.12 nM
CC(C)Oc1cc(C#N)ccc1Nc1ncnc2ccn(C)c12 CHEMBL5195560 pIC50 50.12 nM
CNC(=O)c1nc2c(Nc3ccc(F)cc3OC(C)C)ncnc2s1 CHEMBL5195407 pIC50 50.12 nM
CC(C)Oc1cc(F)ccc1Nc1ncnc2sc(C(=O)NCCN3CCNCC3)nc12 CHEMBL5205835 pIC50 50.12 nM
CC(C)Oc1cc(F)ccc1Nc1ncnc2sc(C(=O)NCC3CCNCC3)nc12 CHEMBL5197975 pIC50 50.12 nM
Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3O[C@H](C)C(=O)NC(C(F)(F)F)C(F)(F)F)c12 CHEMBL4107951 IC50 51.0 nM
CCNC(=O)[C@@H](C)Oc1cc(F)ccc1Nc1ncnc2cc(N=S(C)(C)=O)cc(C)c12 CHEMBL4115253 IC50 51.0 nM
Cc1cc(Nc2cc(N3CCN(C)CC3)ncn2)c(=O)n2c1C(=O)NC21CCCCC1 CHEMBL4787265 IC50 51.2 nM
Cc1cc(Nc2ccnc(N)c2)c(=O)n2c1C(=O)NC21CCCCC1 CHEMBL4740694 IC50 52.3 nM
Cc1cc([C@@H](C)Oc2ncccc2Nc2ncnc3cc(N=S(C)(C)=O)cc(Cl)c23)on1 CHEMBL4113944 IC50 53.0 nM
Cc1cc([C@@H](C)Oc2cc(F)ccc2Nc2ncnc3cc(N=S(C)(C)=O)cc(Cl)c23)on1 CHEMBL4109804 IC50 54.0 nM
Cc1[nH]ncc1-c1cncc(-c2ccc(C(N)=O)c(OC(C)C)c2)c1 CHEMBL4569209 IC50 54.0 nM
Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3O[C@H](C)C(=O)NCC(F)(F)F)c12 CHEMBL4115507 IC50 55.0 nM
CC(=O)Nc1cccc(Cn2cc(-c3ccc4c(N)n[nH]c4c3)ccc2=O)c1 CHEMBL4785028 IC50 55.0 nM
Cc1cc(Nc2cc(NC3CCNCC3)ncn2)c(=O)n2c1C(=O)NC21CCCCC1 CHEMBL4793971 IC50 55.2 nM
C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O CHEMBL603469 Kd 56.0 nM
Nc1n[nH]c2cc(-c3ccc(=O)n(Cc4cccc(C(F)(F)F)c4)c3)ccc12 CHEMBL4757431 IC50 56.0 nM
O=c1ccc(-c2n[nH]c3ncc(Br)cc23)cn1Cc1ccccc1 CHEMBL4743561 IC50 56.0 nM
CC(C)C[C@H](N)c1cc(C#N)c2cc(-c3ccncc3)ccc2n1 CHEMBL5202351 IC50 57.0 nM
Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OC(CF)CF)c12 CHEMBL3966399 IC50 60.0 nM
CS(=O)(=O)CCCOc1ccc2ncc(-c3cc4ncccc4o3)n2n1 CHEMBL3939567 IC50 60.0 nM
NC(=O)c1ccc(Nc2ncnc3[nH]cnc23)cc1 CHEMBL1241463 IC50 60.0 nM
CC1(C)NC(=O)c2ccc(Nc3ccncn3)c(=O)n21 CHEMBL4071021 IC50 60.0 nM
CN1CCN(C(=O)c2ccc(-c3cn4c(-c5ccc(C(=O)NO)cc5)cnc4cn3)cc2)CC1 CHEMBL4214092 IC50 60.0 nM
Cc1c(-c2cncc(-c3ccc(C(N)=O)c(OC(C)C)c3)c2)cnn1C CHEMBL4440223 IC50 60.0 nM
Cc1c(-c2cnc3ccc(OCCCS(C)(=O)=O)nn23)oc2ccccc12 CHEMBL3954138 IC50 61.0 nM
O=c1ccc(-c2ccc3cn[nH]c3c2)cn1Cc1ccc(Cl)c(Cl)c1 CHEMBL4762761 IC50 62.0 nM
Cn1ccc2ncnc(Nc3ccc(F)cc3O[C@@H]3CCCOC3)c21 CHEMBL5187414 pIC50 63.1 nM
Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3O[C@@H](C)CNC(=O)C(F)(F)F)c12 CHEMBL3953860 IC50 66.0 nM
CC(=O)N1CCN(c2cc(-c3cc(C(F)(F)F)c4c(N)ncnn34)ccc2C#N)C(=O)C1(C)C CHEMBL4064666 IC50 66.0 nM
O=C(c1ccc(-c2ccc3ncc(-c4cnc5ccccc5c4)n3c2)cc1)N1CCNCC1 CHEMBL4869672 IC50 67.6 nM
C[C@@H](Oc1cc(F)ccc1Nc1ncnc2cc(N=S(C)(C)=O)cc(F)c12)C(=O)NCC(F)(F)F CHEMBL4113312 IC50 68.0 nM
CC(=O)N1CCN(c2cc(Nc3cc(C)c4n(c3=O)C3(CCCCC3)NC4=O)ncn2)CC1 CHEMBL4741081 IC50 68.9 nM
Cc1cccc2cc(-c3cnc4ccc(OCCCS(C)(=O)=O)nn34)oc12 CHEMBL3929956 IC50 70.0 nM
COC(=O)[C@@]1(N)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL5209022 IC50 70.0 nM
Cc1cc(N=S2(=O)CCC2)cc2ncnc(Nc3ccc(F)cc3O[C@H](C)C(F)(F)F)c12 CHEMBL4108118 IC50 71.0 nM
COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL1230609 Kd 72.0 nM
c1cc2oc(-c3cnc4ccc(OC[C@H]5CNCCO5)nn34)cc2cn1 CHEMBL4110010 IC50 72.0 nM
O=c1ccc(-c2ccc3cn[nH]c3c2)cn1Cc1cccc(F)c1 CHEMBL4791136 IC50 74.0 nM
Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OCCC(F)(F)F)c12 CHEMBL3940502 IC50 75.0 nM
Cc1cc(N=S2(=O)CCCC2)cc2ncnc(Nc3ccc(F)cc3O[C@H](C)C(=O)NCC(C)(C)O)c12 CHEMBL4108589 IC50 75.0 nM
O=C1NC2(CCCCC2)n2c1c(Cl)cc(Nc1ccncc1F)c2=O CHEMBL4535537 Ki 76.0 nM
Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OCc3ccon3)c12 CHEMBL3904562 IC50 77.0 nM
Nc1n[nH]c2cc(-c3ccc(=O)n(Cc4ccccc4)c3)ccc12 CHEMBL4755524 IC50 79.0 nM
CN(C)C(=O)c1cccc(-c2cnc(N)c(-c3nc4cccc(N5CCNCC5)c4[nH]3)n2)c1 CHEMBL3798066 IC50 80.0 nM
O=c1ccc(-c2ccc3cn[nH]c3c2)cn1Cc1ccccc1Cl CHEMBL4752921 IC50 80.0 nM
CN1CCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc(C#N)cc5)n4c3)cc2)CC1 CHEMBL4204438 IC50 84.0 nM
CC(C)Oc1cc(-c2cncc(-c3cnn(C(C)C)c3)c2)ccc1C(N)=O CHEMBL4588193 IC50 85.0 nM
c1cnc2cc(-c3cnc4ccc(OC[C@H]5CNCCO5)nn34)oc2c1 CHEMBL4113051 IC50 86.0 nM
Cc1c(C(=O)NCCCN(C)C)sc2ncnc(Nc3ccc(F)cc3OC3CCOCC3)c12 CHEMBL3659486 IC50 100.0 nM
CC1(C)NC(=O)c2ccc(Nc3ccncn3)cc21 CHEMBL4086042 IC50 100.0 nM
CNC(=O)c1sc2ncnc(Nc3ccc(F)cc3OC(C)C)c2c1C CHEMBL3632744 Ki 106.0 nM
C=CC(=O)Nc1cc(-n2c(=O)ccc3cnc4ccc(-c5cn[nH]c5)cc4c32)ccc1C CHEMBL4075449 IC50 107.4 nM
O=C(O)c1ccc2c3c1cccc3c(=O)n1c3ccccc3nc21 CHEMBL265470 IC50 120.0 nM
COc1cc2ncnc(Nc3cc(Br)c(O)c(Br)c3)c2cc1OC CHEMBL421942 IC50 120.0 nM
CCOc1cc(C(N)=O)ccc1Nc1ncnc2sc(C(N)=O)c(C)c12 CHEMBL3659484 IC50 120.0 nM
Nc1ncc(-c2ccccc2)cc1-c1nc2ccccc2[nH]1 CHEMBL3799935 IC50 120.0 nM
CC(C)Oc1cc(-c2cncc(-c3cnn(C4CCOC4)c3)c2)ccc1C(N)=O CHEMBL4443472 IC50 120.0 nM
COC(=O)Nc1cc(-c2ccc(OC[C@@](C)(N)CC(C)C)c(Cl)n2)ccn1 CHEMBL5205578 IC50 120.0 nM
O=C(c1ccc(-c2cn3c(-c4ccc(O)cc4)cnc3cn2)cc1)N1CCOCC1 CHEMBL4209905 IC50 125.0 nM
Cc1cc(Nc2cc(N3CCC(N)CC3)ncn2)c(=O)n2c1C(=O)NC21CCCCC1 CHEMBL4797669 IC50 125.0 nM
Cn1ccc2ncnc(Nc3ccc(F)cc3OC3CCCC3)c21 CHEMBL5184155 pIC50 125.89 nM
c1cc(-c2cnn3cc(-c4ccc(OCCN5CCOCC5)cc4)cnc23)ccn1 CHEMBL324153 IC50 130.0 nM
CC(C)Oc1cc(-c2cncc(-c3c[nH]nc3C3CC3)c2)ccc1C(N)=O CHEMBL4462099 IC50 130.0 nM
c1cc2oc(-c3cnc4ccc(OCC[C@@H]5CCCN5)nn34)cc2cn1 CHEMBL3978550 IC50 132.0 nM
O=c1ccc(-c2ccc3cn[nH]c3c2)cn1Cc1ccccc1C(F)(F)F CHEMBL4752471 IC50 133.0 nM
Nc1cccc2c1cnn2-c1ncnc2[nH]ccc12 CHEMBL5173114 Ki 150.0 nM
O=C(c1ccc(-c2ccc3ncc(-c4cnc5ccccc5c4)n3c2)cc1)N1CCOCC1 CHEMBL4862514 IC50 153.7 nM
Cn1ccc2ncnc(Nc3ccc(F)cc3OC(CF)CF)c21 CHEMBL5175341 pIC50 158.49 nM
Cc1cc(Nc2ccnnc2)c(=O)n2c1C(=O)NC21CCCCC1 CHEMBL4760245 IC50 159.8 nM
CC(C)C[C@](C)(N)COc1ccc(-c2ccnc(C(F)F)c2)nc1C(F)F CHEMBL5089410 IC50 160.0 nM
CC(=O)Nc1cccc(Cn2cc(-c3ccc4cn[nH]c4c3)ccc2=O)c1 CHEMBL4750622 IC50 163.0 nM
Nc1cc(-c2cnn3cc(-c4ccc(OCCN5CCOCC5)cc4)cnc23)ccn1 CHEMBL1271533 IC50 164.0 nM
C[C@@H](Oc1cc(F)ccc1Nc1ncnc2cc(N=S(C)(C)=O)cc(F)c12)C(F)(F)F CHEMBL4111983 IC50 164.0 nM
O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL151 IC50 179.0 nM
COCCNC(=O)c1sc2ncnc(Nc3ccc(F)cc3OC3CCOCC3)c2c1C CHEMBL3659485 IC50 180.0 nM
CC(C)C[C@](C)(N)COc1ccc(-c2ccnc(C(F)F)c2)cc1C(F)F CHEMBL5088205 IC50 180.0 nM
Cc1c(C(=O)O)sc2ncnc(Nc3ccc(F)cc3OC(C)C)c12 CHEMBL3632742 Ki 186.0 nM
COC(=O)Nc1cc(-c2ccc(OC[C@@](C)(N)CC(C)C)c(C)n2)ccn1 CHEMBL5170576 IC50 190.0 nM
CN1CCN(Cc2ccc(NC(=O)CNc3ccc(-c4ccc(NC(=O)C5CC5)nc4)cc3F)cc2C(F)(F)F)CC1 CHEMBL3806189 IC50 200.0 nM
CC(C)Oc1cc(-c2cncc(-c3cnn(C4COC4)c3)c2)ccc1C(N)=O CHEMBL4587832 IC50 200.0 nM
Fc1ccc(Nc2ncnc3sc4c(c23)CCNC4)c(OC2CCOCC2)c1 CHEMBL3659489 IC50 210.0 nM
Cc1c(C(=O)NCCN2CCOCC2)sc2ncnc(Nc3ccc(F)cc3OC3CCOCC3)c12 CHEMBL3659487 IC50 210.0 nM
CN1CCN(C(=O)c2ccc(-c3nn4c(-c5ccncc5)cnc4s3)cc2)CC1 CHEMBL5268626 IC50 210.2 nM
CC(=O)N1CCN(C(=O)c2ccc(-c3cn4c(-c5ccc(O)cc5)cnc4cn3)cc2)CC1 CHEMBL4208890 IC50 220.0 nM
O=C1NC2(CCCCC2)n2c1c(Cl)cc(Nc1ccnc(O)c1)c2=O CHEMBL4454334 Ki 221.0 nM
Cc1cc(N=S2(=O)CCCC2)cc2ncnc(Nc3ccc(F)cc3OC(C)C(C)(C)O)c12 CHEMBL3930942 IC50 228.0 nM
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1 CHEMBL1336 Kd 230.0 nM
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC CHEMBL475251 Kd 230.0 nM
CN(C)C1CCN(C(=O)c2ccc(-c3cn4c(-c5ccc(C#N)cc5)cnc4cn3)cc2)CC1 CHEMBL4208246 IC50 238.0 nM
Cc1cc(Nc2ccncc2)c(=O)n2c1C(=O)NC21CCCCC1 CHEMBL4751127 IC50 239.8 nM
Cc1cc(-c2cc(C(F)F)c(OC[C@@](C)(N)CC(C)C)cn2)ccn1 CHEMBL4092824 IC50 250.0 nM
C=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCN1CCOCC1 CHEMBL31965 Kd 260.0 nM
CC(C)C[C@](C)(N)COc1cnc(-c2ccnc(C(F)F)c2)cc1C(F)F CHEMBL5199698 IC50 260.0 nM
CN1CCN(C(=O)c2ccc(-c3cn4c(-c5ccc(O)cc5)cnc4cn3)cc2)CC1 CHEMBL4209496 IC50 280.0 nM
Nc1cccc(Cn2cc(-c3ccc4cn[nH]c4c3)ccc2=O)c1 CHEMBL4759018 IC50 287.0 nM
COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1 CHEMBL939 Kd 290.0 nM
CN1CCN(C(=O)c2ccc(-c3cn4c(-c5ccc(C(N)=O)cc5)cnc4cn3)cc2)CC1 CHEMBL4204506 IC50 290.0 nM
Cc1cc(Nc2ncnc3sc(C(=O)O)c(C)c23)c(=O)n(C)c1 CHEMBL3417198 Ki 300.0 nM
NC(=O)c1ccc(-c2cn3c(-c4ccc(O)cc4)cnc3cn2)cc1 CHEMBL4212480 IC50 310.0 nM
CC(C)Oc1cc(-c2cncc(-c3nn[nH]n3)c2)ccc1C(N)=O CHEMBL4587472 IC50 310.0 nM
O=c1ccc(-c2ccc3cn[nH]c3c2)cn1Cc1ccccc1 CHEMBL4789590 IC50 315.0 nM
COCCCNC(=O)c1sc2ncnc(Nc3ccc(F)cc3OC(C)C)c2c1C CHEMBL3632747 Ki 320.0 nM
COc1cc(O)c2c(c1)CCC[C@H](O)[C@H](O)C(=O)/C=C\C[C@H](C)OC2=O CHEMBL2012519 IC50 325.0 nM
CN1CCN(C(=O)c2ccc(-c3cn4c(-c5ccc(Cl)cc5)cnc4cn3)cc2)CC1 CHEMBL4211757 IC50 330.0 nM
O=C1NC2(CCCCC2)n2c1c(Cl)cc(Nc1ccon1)c2=O CHEMBL4466664 Ki 341.0 nM
O=C(COc1ccc(-c2cccnc2)cc1)Nc1ccc(CN2CCNCC2)c(C(F)(F)F)c1 CHEMBL3805029 IC50 350.0 nM
CCN1CCN(Cc2ccc(NC(=O)CNc3ccc(-c4cccnc4)cc3)cc2C(F)(F)F)CC1 CHEMBL3806261 IC50 350.0 nM
COc1cc2/c(=N/c3ccc(Br)cc3F)nc[nH]c2cc1OCC1CCN(C)CC1 CHEMBL24828 Kd 360.0 nM
CN1CCN(C(=O)c2ccc(-c3cn4c(-c5ccc(C(F)F)cc5)cnc4cn3)cc2)CC1 CHEMBL4202593 IC50 369.0 nM
CCN1CCN(Cc2ccc(NC(=O)Cc3ccc(Oc4ccnc(NC)c4)cc3)cc2C(F)(F)F)CC1 CHEMBL3804952 IC50 370.0 nM
O=C(c1ccc(-c2ccc3ncc(-c4ccc5ncccc5c4)n3c2)cc1)N1CCOCC1 CHEMBL4848427 IC50 370.8 nM
COC(=O)c1ccc(-c2cnc3sc(-c4ccc(C(=O)N5CCN(C)CC5)cc4)nn23)cc1 CHEMBL5289237 IC50 375.5 nM
NC(=O)c1cccc(Cn2cc(-c3ccc4cn[nH]c4c3)ccc2=O)c1 CHEMBL4790632 IC50 388.0 nM
COc1nccc2oc(-c3cnc4ccc(O[C@@H](CNC5CC5)c5ccc(F)cc5)nn34)cc12 CHEMBL3911648 IC50 389.0 nM
Cc1cc(Nc2ccnc(N)n2)c(=O)n2c1C(=O)NC21CCCCC1 CHEMBL4784364 IC50 390.0 nM
Cc1c(C(N)=O)sc2ncnc(Nc3ccc(F)cc3OC3CCN(CC(=O)N4CCOCC4)CC3)c12 CHEMBL3659492 IC50 400.0 nM
CC(C)Oc1cc(-c2cncc(-c3cnn(C)c3)c2)ccc1C(N)=O CHEMBL4457274 IC50 400.0 nM
Cc1cc(Nc2cc(C)c3n(c2=O)C2(CCCCC2)NC3=O)ccn1 CHEMBL4741111 IC50 422.0 nM
Cc1c(C(N)=O)sc2ncnc(Nc3ccc(F)cc3OC3CCN(Cc4ncon4)CC3)c12 CHEMBL3659490 IC50 460.0 nM
Cc1cc(Nc2cnccn2)c(=O)n2c1C(=O)NC21CCCCC1 CHEMBL4757777 IC50 466.0 nM
Cc1cc(Nc2cc(N3CCCCC3)ncn2)c(=O)n2c1C(=O)NC21CCCCC1 CHEMBL4752750 IC50 476.0 nM
Cc1cc(Nc2cn(C)nc2N)c(=O)n2c1C(=O)NC21CCCCC1 CHEMBL4743829 IC50 479.0 nM
CC(C)C[C@](C)(N)COc1cnc(-c2ccnc(Cl)c2)cc1C(F)F CHEMBL5194667 IC50 490.0 nM
CN1CCN(C(=O)c2ccc(-c3cn4c(-c5ccc(C#N)cc5)cnc4cn3)cc2)CC1 CHEMBL4216991 IC50 499.0 nM
CC(=O)C1=C(O)C=C2Oc3c(C(N)=O)c(O)cc(O)c3[C@@]2(C)C1=O CHEMBL3416305 Ki 507.0 nM
CC(C)C[C@@H](N)C(=O)Nc1ccc(-c2cnco2)c(OC(F)F)c1 CHEMBL4872886 IC50 507.0 nM
O=C(CNc1ccc(-c2ccc(NC(=O)C3CC3)nc2)cc1)Nc1ccc(CN2CCNCC2)c(C(F)(F)F)c1 CHEMBL3805330 IC50 510.0 nM
Oc1ccc(-c2cnc3cnc(-c4ccccc4)cn23)cc1 CHEMBL4213023 IC50 528.0 nM
COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OC CHEMBL7917 IC50 530.0 nM
CCN1CCN(Cc2ccc(NC(=O)Cc3ccc(Oc4ccncc4)cc3)cc2C(F)(F)F)CC1 CHEMBL3805114 IC50 540.0 nM
CCN1CCN(Cc2ccc(NC(=O)COc3ccc(-c4cccnc4)cc3)cc2C(F)(F)F)CC1 CHEMBL3805956 IC50 570.0 nM
N#Cc1ccc(-c2cnc3cnc(-c4ccc(C(=O)N5CCOCC5)cc4)cn23)cc1 CHEMBL4213819 IC50 570.0 nM
CN1CCN(C(=O)c2ccc(-c3cn4c(-c5ccc(C(F)(F)F)cc5)cnc4cn3)cc2)CC1 CHEMBL4212200 IC50 570.0 nM
Clc1ccc(Nc2ncnc3[nH]ncc23)cc1 CHEMBL1240786 IC50 580.0 nM
COC(=O)c1sc2ncnc(Nc3ccc(F)cc3OC(C)C)c2c1C CHEMBL3632739 IC50 590.0 nM
Cc1ccc(-c2cnc3cnc(-c4ccc(C(=O)N5CCN(C)CC5)cc4)cn23)cc1 CHEMBL4212307 IC50 600.0 nM
COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC CHEMBL29197 IC50 630.0 nM
c1cc(-c2cc(C3CCNCC3)n[nH]2)ccn1 CHEMBL1241462 IC50 646.0 nM
COc1ccc(S(=O)(=O)N2CCc3c(sc4ncnc(Nc5ccc(F)cc5OC)c34)C2)cc1 CHEMBL4462979 IC50 650.0 nM
Cc1c(C(=O)NCCCN(C)C)sc2ncnc(Nc3ccc(C(F)(F)F)nc3OC3CCOCC3)c12 CHEMBL3659488 IC50 680.0 nM
C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)cc23)c1 CHEMBL553 Kd 690.0 nM
NC(=O)c1ccc(Nc2ccncn2)cc1 CHEMBL4071844 IC50 690.0 nM
Nc1n[nH]c2nc(-c3ccccc3)cc(-c3ccccc3)c12 CHEMBL5189796 IC50 690.0 nM
Nc1ncccc1-c1nc2ccccc2[nH]1 CHEMBL3797559 IC50 700.0 nM
CN1CCN(C(=O)c2ccc(-c3cn4c(-c5ccc(C(=O)O)cc5)cnc4cn3)cc2)CC1 CHEMBL4217366 IC50 700.0 nM
COc1ccc(Nc2nccc(-c3cn(C(C)C)c4ccccc34)n2)c(OC)c1 CHEMBL4159011 Ki(app) 710.0 nM
COc1ncc(C)cc1Nc1ncnc2[nH]ccc12 CHEMBL5180079 Ki 740.0 nM
CC(=O)Nc1cn2c(-c3ccc(O)cc3)cnc2cn1 CHEMBL4208627 IC50 789.0 nM
Cn1cc(-c2cncc(-c3ccc(C(N)=O)cc3)c2)cn1 CHEMBL4457368 IC50 800.0 nM
NCCOc1cc(-c2cccnc2)ccc1C(N)=O CHEMBL4537933 IC50 820.0 nM
COc1ccc(S(=O)(=O)N2CCc3c(sc4ncnc(Nc5ccc(F)cc5F)c34)C2)cc1 CHEMBL4532338 IC50 830.0 nM
COC(=O)c1ccc(Nc2[nH]cnc3ncnc2-3)cc1 CHEMBL195744 IC50 850.0 nM
Nc1ncnc2[nH]nc(Nc3ccc(F)cc3)c12 CHEMBL1240885 IC50 850.0 nM
COc1ccc(Nc2nccc(-c3sc(N(C)C)nc3C)n2)c(OC)c1 CHEMBL4162390 Ki(app) 860.0 nM
NC(=O)c1ccccc1Cn1cc(-c2ccc3cn[nH]c3c2)ccc1=O CHEMBL4763087 IC50 878.0 nM
Nc1nc(N)c2nc(-c3cccc(O)c3)c(-c3cccc(O)c3)nc2n1 CHEMBL230011 Kd 880.0 nM
CC(C)Oc1cc(-c2cccnc2)ccc1C(N)=O CHEMBL4450463 IC50 880.0 nM
Oc1ccccc1Nc1nccc(-c2c[nH]c3ccccc23)n1 CHEMBL4165526 Ki(app) 890.0 nM
CC(C)Oc1cc(-c2cncc(N3CCOCC3)c2)ccc1C(N)=O CHEMBL4465294 IC50 900.0 nM
COc1cc(F)ccc1Nc1ncnc2sc3c(c12)CCN(C)C3 CHEMBL4521686 IC50 930.0 nM
COc1cc(F)ccc1Nc1ncnc2sc3c(c12)CCN(S(=O)(=O)c1ccc(F)cc1F)C3 CHEMBL4450446 IC50 930.0 nM
CCNC(=O)c1sc2ncnc(Nc3ccc(F)cc3OC(C)C)c2c1C CHEMBL3632745 Ki 933.0 nM
COc1ccc(Nc2nccc(-c3cn(C)c4ccccc34)n2)c(OC)c1 CHEMBL4165841 Ki(app) 940.0 nM
COc1cc(F)ccc1Nc1ncnc2sc3c(c12)CCN(S(=O)(=O)c1cccs1)C3 CHEMBL4450194 IC50 940.0 nM
Oc1ccc(-c2cnn3cc(-c4ccc(OCCN5CCOCC5)cc4)cnc23)cc1O CHEMBL1271641 IC50 950.0 nM
O=S(=O)(c1cccs1)N1CCc2c(sc3ncnc(Nc4ccc(F)cc4Br)c23)C1 CHEMBL4554398 IC50 970.0 nM
COc1cc(F)ccc1Nc1ncnc2sc3c(c12)CCN(Cc1ccccc1)C3 CHEMBL4447000 IC50 1000.0 nM
COc1ccc(S(=O)(=O)N2CCc3c(sc4ncnc(Nc5ccc(F)cc5Br)c34)C2)cc1 CHEMBL4537838 IC50 1000.0 nM