CC(C)CN(CC(C)C)C(=O)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL205986 IC50 0.07 nM
CCN(CCC#N)C(=O)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL380487 IC50 0.29 nM
NC(=O)C1(c2cccc(C(=O)O)c2)CCN(c2ncc(C(O)(C(F)(F)F)C(F)(F)F)s2)CC1 CHEMBL1258253 IC50 0.5 nM
O=C(O)c1cccc(C2(C(=O)O)CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)c1 CHEMBL1258254 IC50 0.6 nM
O=C(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)N1CCCC1 CHEMBL205506 IC50 0.85 nM
O=C(O)c1cccc(C2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)c1 CHEMBL1257549 IC50 0.9 nM
CS(=O)(=O)NC(=O)C1(c2ccccc2)CCN(c2ncc(C(O)(C(F)(F)F)C(F)(F)F)s2)CC1 CHEMBL1258367 IC50 0.9 nM
O=C(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)N1CCCCC1 CHEMBL204287 IC50 0.98 nM
CN(Cc1ccccc1)C(=O)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202688 IC50 1.0 nM
O=C(O)C1(c2ccccc2)CCN(c2ncc(C(O)(C(F)(F)F)C(F)(F)F)s2)CC1 CHEMBL1257909 IC50 1.1 nM
O=C(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)N1CCOCC1 CHEMBL206852 IC50 1.14 nM
O=C(O)c1cccc(N2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)c1 CHEMBL1258699 IC50 1.3 nM
O=C(O)C1(c2ccc(F)cc2)CCN(c2ncc(C(O)(C(F)(F)F)C(F)(F)F)s2)CC1 CHEMBL1258139 IC50 1.4 nM
CON(C)C(=O)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202689 IC50 1.45 nM
OC(c1cnc(N2CCN(c3cccc(-c4nnn[nH]4)c3)CC2)s1)(C(F)(F)F)C(F)(F)F CHEMBL1258935 IC50 1.6 nM
OC(c1cnc(N2CCC(c3nnn[nH]3)(c3ccccc3F)CC2)s1)(C(F)(F)F)C(F)(F)F CHEMBL1258140 IC50 1.6 nM
O=C(O)c1ccccc1C1CCN(c2ncc(C(O)(C(F)(F)F)C(F)(F)F)s2)CC1 CHEMBL1257548 IC50 1.7 nM
NC(=O)c1cccc(C2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)c1 CHEMBL1257669 IC50 1.8 nM
CN(CCc1ccccc1)C(=O)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202746 IC50 1.99 nM
NC(=O)c1cccc(N2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)c1 CHEMBL1258820 IC50 2.2 nM
CNC(=O)c1cccc(N2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)c1 CHEMBL1258936 IC50 2.3 nM
O=C(NCCc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL203835 IC50 2.65 nM
Nc1ccc(N2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)cc1 CHEMBL1258591 IC50 2.7 nM
CNC(=O)c1cccc(C2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)c1 CHEMBL1257791 IC50 3.1 nM
Nc1cccc(N2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)c1 CHEMBL1258590 IC50 3.2 nM
O=C(NCC(F)(F)F)C1(c2ccccc2)CCN(c2ncc(C(O)(C(F)(F)F)C(F)(F)F)s2)CC1 CHEMBL1258368 IC50 3.3 nM
O=C(O)c1ccc(C2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)cc1 CHEMBL1257668 IC50 4.0 nM
OC1(c2ccccc2)CCN(c2ncc(C(O)(C(F)(F)F)C(F)(F)F)s2)CC1 CHEMBL1257792 IC50 4.5 nM
CNC(=O)C1(c2ccccc2)CCN(c2ncc(C(O)(C(F)(F)F)C(F)(F)F)s2)CC1 CHEMBL1258020 IC50 4.7 nM
NC(=O)C1(c2ccccc2)CCN(c2ncc(C(O)(C(F)(F)F)C(F)(F)F)s2)CC1 CHEMBL1258019 IC50 4.9 nM
C[C@@H](CC(=O)OC(C)(C)C)NC(=O)C1=NO[C@@H](C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL211177 IC50 5.0 nM
CCC(C)(CC)OC(=O)C[C@H](C)NC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL209844 IC50 5.0 nM
O=C(O)c1ccccc1N1CCN(c2ncc(C(O)(C(F)(F)F)C(F)(F)F)s2)CC1 CHEMBL1258700 IC50 5.1 nM
O=S(=O)(c1ccc(C(F)(F)F)cc1)c1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1 CHEMBL1258701 IC50 5.7 nM
Nc1nc(-c2cc(=O)oc3cc(Sc4ncc(C(O)(C(F)(F)F)C(F)(F)F)s4)ccc23)cs1 CHEMBL1258481 IC50 6.7 nM
C[C@@H](CC(=O)OC(C)(C)C)NC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL208825 IC50 7.0 nM
CCC(C)(CC)OC(=O)CCNC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL209108 IC50 7.0 nM
CC(C)C(=O)N(CCCCc1nnn[nH]1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL400455 pIC50(uM) 7.943 nM
CC(C)C(=O)N(CCCCC(=O)O)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL380868 pIC50(uM) 7.943 nM
C[C@H](CC(=O)OC(C)(C)C)NC(=O)C1=NO[C@@H](C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL378459 IC50 8.0 nM
OC(c1cnc(N2CCN(c3ccc(F)cc3)CC2)s1)(C(F)(F)F)C(F)(F)F CHEMBL1258137 IC50 8.1 nM
OC(c1cnc(N2CCN(c3cccc(F)c3)CC2)s1)(C(F)(F)F)C(F)(F)F CHEMBL1258018 IC50 8.7 nM
O=[N+]([O-])c1ccc(N2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)cc1 CHEMBL1258366 IC50 8.9 nM
CC(C)CC(C)(CC(C)C)OC(=O)CCNC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL208770 IC50 9.0 nM
N#Cc1ccc(CN(C(=O)c2ccncc2)c2ncc(C(O)(C(F)(F)F)C(F)(F)F)s2)cc1 CHEMBL210138 IC50 9.0 nM
C[C@H](CC(=O)OC(C)(C)C)NC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL379321 IC50 10.0 nM
O=C(O)c1ccc(CN(C(=O)c2cc(Cl)cc(Cl)c2)c2ncc(C(O)(C(F)(F)F)C(F)(F)F)s2)cc1 CHEMBL379161 IC50 11.0 nM
OC(c1cnc(N2CCN(c3ccc(F)c(F)c3)CC2)s1)(C(F)(F)F)C(F)(F)F CHEMBL1258138 IC50 11.0 nM
OC(c1cnc(N2CCC(c3cccc(F)c3)CC2)s1)(C(F)(F)F)C(F)(F)F CHEMBL1257433 IC50 11.0 nM
N#CC1(c2ccccc2)CCN(c2ncc(C(O)(C(F)(F)F)C(F)(F)F)s2)CC1 CHEMBL1257908 IC50 11.0 nM
O=[N+]([O-])c1cccc(N2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)c1 CHEMBL1258365 IC50 12.0 nM
OC(c1cnc(N2CCC(c3ccccc3)CC2)s1)(C(F)(F)F)C(F)(F)F CHEMBL1257432 IC50 13.0 nM
Cc1cc(C(O)(C(F)(F)F)C(F)(F)F)ccc1C(Cc1cc[n+]([O-])cc1)c1ccc(OC(F)F)c(OC(F)F)c1 CHEMBL102718 IC50 13.3 nM
O=C(O)CCCCN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL206756 IC50 14.0 nM
NC(=O)c1cccc(N2CCC(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)c1 CHEMBL1257319 IC50 14.0 nM
CC(C)C[C@@H](CC(=O)OC(C)(C)C)NC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL211947 IC50 15.0 nM
N#Cc1cccc(N2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)c1 CHEMBL1258479 IC50 16.0 nM
CC(C)N(C(=O)CCNC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1)C(C)C CHEMBL378896 IC50 17.0 nM
CCCCCN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL203790 IC50 19.0 nM
O=C(O)c1ccc(N2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)cc1 CHEMBL1258819 IC50 19.0 nM
OC(c1cnc(C2CCN(c3ccc(F)cc3)CC2)s1)(C(F)(F)F)C(F)(F)F CHEMBL1257318 IC50 19.0 nM
CC(C)C(=O)N(CCCCC#N)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL382695 pIC50(uM) 19.95 nM
CCCCN(C(=O)C(C)C)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL206438 pIC50(uM) 19.95 nM
CC(C)C(=O)N(Cc1ccc(C#N)cc1)c1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1 CHEMBL210190 pIC50(uM) 19.95 nM
CC(C)C(=O)N(Cc1ccncc1)c1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1 CHEMBL385355 IC50 20.0 nM
OC(c1cnc(N2CCN(c3ccccc3)CC2)s1)(C(F)(F)F)C(F)(F)F CHEMBL1257547 IC50 20.0 nM
CCN(C(=O)C(C)C)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)nc1 CHEMBL209430 IC50 22.0 nM
O=C(c1ccncc1)N(Cc1ccncc1)c1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1 CHEMBL211235 IC50 22.0 nM
CC(CC(=O)OC(C)(C)C)NC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL213556 IC50 23.0 nM
CCN(CCC#N)C(=S)N(CC1CCOC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)nc1 CHEMBL378202 IC50 24.0 nM
CS(=O)(=O)c1cccc(N2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)c1 CHEMBL1258251 IC50 24.0 nM
COC(=O)CCCCN(C(=O)C(C)C)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202632 pIC50(uM) 25.7 nM
CCCN(C(=O)C(C)C)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL381996 IC50 28.0 nM
CC(C)(C)OCCCNC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL211294 IC50 28.0 nM
CC(C)CCCC(C)NC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL209067 IC50 28.0 nM
CCCCN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202905 IC50 30.0 nM
CC(C)CC(CC(=O)OC(C)(C)C)NC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL211948 IC50 30.0 nM
CCCCCCN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL381564 pIC50(uM) 30.9 nM
CC(C)(C)OC(=O)CCNC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL209212 IC50 31.0 nM
CCCN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL205932 pIC50(uM) 33.88 nM
COC(=O)CN(C(=O)C(C)C)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL383498 IC50 34.0 nM
OC(c1cnc(C2CCN(c3cccc(F)c3)CC2)s1)(C(F)(F)F)C(F)(F)F CHEMBL1257201 IC50 36.0 nM
CCN(C(=O)c1ccc(C#N)cc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL203991 IC50 37.0 nM
CC(C)CC(C)(CC(C)C)OC(=O)CC(C)NC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL212359 IC50 37.0 nM
CCOC(=O)C(C)Cc1cnc(C(C)C)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL377710 IC50 37.0 nM
OC(c1cnc(C2CCN(c3ccccc3)CC2)s1)(C(F)(F)F)C(F)(F)F CHEMBL1257200 IC50 37.0 nM
N#CCCCN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL380746 IC50 40.0 nM
CCN(C(=O)C(C)C)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL383478 pIC50(uM) 40.74 nM
CCC(C)c1ncc(CCC(=O)OC)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL201846 pIC50(uM) 40.74 nM
COC(=O)CCCCN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL206562 pIC50(uM) 41.69 nM
N#Cc1ccc(N2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)cc1 CHEMBL1258480 IC50 42.0 nM
O=C(N1CCOCC1)N(CCc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL205117 pIC50(uM) 42.66 nM
CC(C)C1N=C/C(=N/OC(C)(C)C)N1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL252977 pIC50(uM) 43.65 nM
CS(=O)(=O)c1ccc(N2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)cc1 CHEMBL1258252 IC50 44.0 nM
CC(C)C[C@H](CC(=O)OC(C)(C)C)NC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL378888 IC50 45.0 nM
COc1cccc(N2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)c1 CHEMBL1257907 IC50 46.0 nM
CC(C)CN(CC(C)C)C(=O)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)nc1 CHEMBL212692 IC50 47.0 nM
COC(=O)c1ccc(CN(C(=O)C(C)C)c2ncc(C(O)(C(F)(F)F)C(F)(F)F)s2)cc1 CHEMBL211767 pIC50(uM) 53.7 nM
CCC(C)c1ncc(C(O)C(C)C)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL370452 pIC50(uM) 58.88 nM
CCN(C(=O)N(C)C)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL382600 IC50 59.0 nM
Cc1ccc(N2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)cc1 CHEMBL1257790 IC50 59.0 nM
CCN(CCCCO)C(=O)N(CC)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL205462 IC50 60.0 nM
CCCCCC(C)NC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL211992 IC50 60.0 nM
COC(=O)CCc1cnc(C(C)C)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202161 pIC50(uM) 64.57 nM
CCCN(CC1CC1)C(=O)c1ccc(C(=O)C(F)(F)F)cc1 CHEMBL247462 IC50 68.0 nM
CCCCCCCN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL205719 pIC50(uM) 72.44 nM
CC(C)CN(CC(C)C)C(=O)c1ccc(C(=O)C(F)(F)F)cc1 CHEMBL396148 IC50 73.0 nM
CCN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL205931 IC50 74.0 nM
COC(=O)CCCN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL382246 IC50 75.0 nM
COc1ccc(N2CCN(c3ncc(C(O)(C(F)(F)F)C(F)(F)F)s3)CC2)cc1 CHEMBL1257906 IC50 76.0 nM
CCCCN(C(=O)CCc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL204960 IC50 79.0 nM
OC(c1cnc(N2CCN(c3cccc(Cl)c3)CC2)s1)(C(F)(F)F)C(F)(F)F CHEMBL1258017 IC50 79.0 nM
COC(=O)CN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL378375 IC50 80.0 nM
CC(C)CN(CCOC(=O)c1cccc([N+](=O)[O-])c1)C(=O)c1ccc(C(=O)C(F)(F)F)cc1 CHEMBL392724 IC50 80.0 nM
OC(c1ccc(N(CC2CCOC2)C(=S)N2CCOCC2)cn1)(C(F)(F)F)C(F)(F)F CHEMBL210925 IC50 84.0 nM
CCC(C)c1ncc(/C=C/C(=O)OC)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL370451 pIC50(uM) 87.1 nM
Cc1ccc(Sc2ncc(C(O)(C(F)(F)F)C(F)(F)F)s2)cc1 CHEMBL1258592 IC50 92.0 nM
CCN(C(=O)c1ccncc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL382794 IC50 95.0 nM
COC(=O)CCN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL203871 IC50 99.0 nM
COC(=O)CN(C(=O)CCc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL381580 IC50 105.0 nM
CC(C)C(=O)N(CCO)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL204109 IC50 106.0 nM
CC(C)c1ncc(COCCCCC#N)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL440043 IC50 107.0 nM
OC(c1cnc(N2CCN(c3ccc(C(F)(F)F)cc3)CC2)s1)(C(F)(F)F)C(F)(F)F CHEMBL1257789 IC50 110.0 nM
CCCCN(C(=O)c1ccncc1)c1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1 CHEMBL441535 IC50 111.0 nM
CC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL210509 IC50 113.0 nM
OCc1cnc(-c2ccncc2)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL383613 IC50 114.0 nM
CC(C)c1ncc(COCCCCc2nnn[nH]2)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202016 pIC50(uM) 114.82 nM
CCCCCC(C)NC(=O)c1ccc(C(=O)C(F)(F)F)cc1 CHEMBL245824 IC50 115.0 nM
CCCN(CC1CC1)C(=O)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)nc1 CHEMBL211238 IC50 117.0 nM
CCO/N=C1/C=NC(C(C)C)N1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL399897 pIC50(uM) 117.49 nM
C[C@@H](CC(=O)OC(C)(C)C)NC(=O)C1=NO[C@H](C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL386147 IC50 136.0 nM
CC(C)CN(CC(C)C)C(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL211594 IC50 137.0 nM
CCCCC(=O)Nc1onc(C(C)C)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL201995 IC50 140.0 nM
CC(C)c1ncc(/C=C/C#N)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL381423 IC50 140.0 nM
CCC(C)c1ncc(C(C)O)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202008 pIC50(uM) 147.91 nM
CC(C)C(=O)N(Cc1ccc(Cl)cc1)c1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1 CHEMBL212691 IC50 148.0 nM
O=C(CCc1ccccc1)N(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)C1CCCCC1 CHEMBL381266 IC50 150.0 nM
CC(C)C1N=C/C(=N/O)N1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL254034 pIC50(uM) 151.36 nM
CCCN(CCC)C(=O)c1ccc(C(=O)C(F)(F)F)cc1 CHEMBL247256 pIC50(uM) 151.36 nM
CC(C)c1ncc(COCCCCCc2nnn[nH]2)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL402264 pIC50(uM) 154.88 nM
N#CCCN(C(=O)c1ccc(C(=O)C(F)(F)F)cc1)c1ccccc1 CHEMBL245830 pIC50(uM) 154.88 nM
CCC(C)c1ncc(CCC(=O)O)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL203691 pIC50(uM) 162.18 nM
O=C(N1CCOCC1)N(CCO)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL204273 pIC50(uM) 165.96 nM
C[C@H](CC(=O)OC(C)(C)C)NC(=O)C1=NO[C@H](C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL209829 IC50 168.0 nM
CC(C)c1ncc(COCCCCCC#N)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202772 IC50 168.0 nM
CCN(C(=O)CCc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL205016 IC50 175.0 nM
CCCCN(C(C)=O)c1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1 CHEMBL377742 IC50 177.0 nM
CC(C)C(=O)N(C)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL206808 pIC50(uM) 177.83 nM
CC(C)C(=O)N(Cc1ccccn1)c1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1 CHEMBL379061 IC50 187.0 nM
Nc1onc(-c2ccncc2)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202404 IC50 190.0 nM
CCOC(=O)c1cn(-c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)c(-c2ccncc2)n1 CHEMBL370601 pIC50(uM) 190.55 nM
CC(C)N(C(=O)CCc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL204767 IC50 199.0 nM
CCCCC(CC)C(=O)Nc1onc(C(C)C)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202276 pIC50(uM) 199.53 nM
CC(C)C1N=C/C(=N/Oc2ccccc2)N1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL252776 pIC50(uM) 208.93 nM
CCN(CCC#N)C(=O)c1ccc(C(=O)C(F)(F)F)cc1 CHEMBL246033 pIC50(uM) 213.8 nM
CC(Cc1cnc(C(C)C)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)C(=O)O CHEMBL202333 pIC50(uM) 223.87 nM
CC(C)CN(CC(C)C)C(=O)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)[n+]([O-])c1 CHEMBL211217 IC50 235.0 nM
CC(C)c1ncc(CCC(=O)O)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL378578 IC50 239.0 nM
CC(C)CC(C)NC(=O)c1ccc(C(=O)C(F)(F)F)cc1 CHEMBL246029 pIC50(uM) 239.88 nM
OC(c1cnc(N2CCN(c3cccc(C(F)(F)F)c3)CC2)s1)(C(F)(F)F)C(F)(F)F CHEMBL1257666 IC50 240.0 nM
O=C(O)CCN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL203516 pIC50(uM) 245.47 nM
CC(C)C(=O)Nc1onc(-c2ccncc2)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202467 IC50 250.0 nM
CCCCCCCCN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL204248 IC50 269.0 nM
CC(C)c1ncc(CO)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL370815 IC50 274.0 nM
Cc1onc(/C=C/C#N)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL201855 pIC50(uM) 288.4 nM
CC1CCCCC1NC(=O)c1ccc(C(=O)C(F)(F)F)cc1 CHEMBL396690 pIC50(uM) 302.0 nM
CCCCNCc1cnc(C(C)CC)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL201153 pIC50(uM) 302.0 nM
CCOC(=O)c1cn(-c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)c(C(C)CC)n1 CHEMBL202205 pIC50(uM) 316.23 nM
OC(c1cnc(N2CCN(c3cccc(OC(F)(F)F)c3)CC2)s1)(C(F)(F)F)C(F)(F)F CHEMBL1257667 IC50 320.0 nM
CN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL206341 IC50 321.0 nM
CCC(C)c1ncc(CNCCOC)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202543 pIC50(uM) 338.84 nM
CC(C)c1noc(NC(=O)c2ccncc2)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202019 pIC50(uM) 338.84 nM
CC(C)CO/N=C1\CN=C(C(C)C)N1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL255089 pIC50(uM) 346.74 nM
CC(C)CO/N=C1/CN=C(C(C)C)N1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL201244 IC50 350.0 nM
COc1ccc(CN(C(=O)C(C)C)c2ncc(C(O)(C(F)(F)F)C(F)(F)F)s2)cc1 CHEMBL378879 IC50 353.0 nM
CC(C)C(=O)N(Cc1nccn1C)c1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1 CHEMBL210650 IC50 356.0 nM
O=C(O)CN(C(=O)CCc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL206201 IC50 376.0 nM
Cc1onc(NC(=O)c2ccncc2)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL383009 pIC50(uM) 389.05 nM
CC(C)c1noc(NC(=O)c2ccc(C#N)cc2)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202168 pIC50(uM) 389.05 nM
CN(C(=O)c1ccncc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL380364 IC50 394.0 nM
CCN(CC(C)(C)O)C(=O)c1ccc(C(=O)C(F)(F)F)cc1 CHEMBL246034 IC50 399.0 nM
Cc1noc(C)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202488 pIC50(uM) 407.38 nM
CCC(C(=O)Nc1onc(C(C)C)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)c1ccccc1 CHEMBL201996 pIC50(uM) 416.87 nM
CCOC(=O)CCCNC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL210137 IC50 421.0 nM
CC(C)C(=O)N(Cc1ccc(Cl)c(Cl)c1)c1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1 CHEMBL209976 IC50 438.0 nM
OC(c1cnc(Oc2ccccc2)s1)(C(F)(F)F)C(F)(F)F CHEMBL1258594 IC50 450.0 nM
CC(C)c1noc(N)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL377926 IC50 460.0 nM
CCOC(=O)CCNC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL379846 IC50 463.0 nM
CCC(C)c1ncc(C(O)c2ccccc2)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL264476 IC50 465.0 nM
CC(C)(C)CCNC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL377830 IC50 489.0 nM
O=C(NCc1cccc(C(F)(F)F)c1)c1ccc(C(=O)C(F)(F)F)cc1 CHEMBL437954 IC50 507.0 nM
CCCCN(C(=O)CCC)c1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1 CHEMBL211056 IC50 526.0 nM
O=C(NCCc1ccccc1)c1ccc(C(=O)C(F)(F)F)cc1 CHEMBL397381 pIC50(uM) 562.34 nM
O=C(CCc1ccccc1)N(Cc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL206570 IC50 580.0 nM
Cc1ccc(Sc2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)cc1 CHEMBL1258593 IC50 600.0 nM
CC(C)C(=O)N(CC(=O)O)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL203444 IC50 627.0 nM
CCOCc1noc(N)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202022 IC50 630.0 nM
Nc1onc(CCCO)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL202654 IC50 650.0 nM
O=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccc(C(=O)C(F)(F)F)cc1 CHEMBL245625 IC50 654.0 nM
CCCCc1noc(N)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL203588 IC50 670.0 nM
CC(C)CN(C)C(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL211541 IC50 676.0 nM
CCCCCCNC(=O)c1ccc(C(=O)C(F)(F)F)cc1 CHEMBL449355 IC50 679.0 nM
CCc1noc(N)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL204498 IC50 680.0 nM
CC(C)C(=O)N(Cc1ccccc1)c1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1 CHEMBL378975 IC50 689.0 nM
CC(C)C(=O)Nc1onc(-c2ccccc2)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL383490 IC50 730.0 nM
CN(C(=O)CCc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL427589 IC50 773.0 nM
CCN(C(=O)C(C)C)c1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1 CHEMBL378457 IC50 794.0 nM
CC(C)CNC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 CHEMBL211319 IC50 801.0 nM
CCCC(=O)c1noc(C)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL373070 IC50 930.0 nM
CN(C(=O)COc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL203290 IC50 930.0 nM
CN(CCc1ccccc1)C(=O)c1ccc(C(=O)C(F)(F)F)cc1 CHEMBL245829 IC50 953.0 nM
CCOC(=O)c1noc(C)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL382503 IC50 960.0 nM
CCCCN(C(=O)C(C)C)c1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1 CHEMBL212381 IC50 984.0 nM
Cc1onc(NC(=O)C(C)C)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL380764 IC50 990.0 nM