CCCO[C@H](c1cccc(-c2csc(NC(=O)c3cc(Cl)c(/C=C(\C)C(=O)O)c(Cl)c3)n2)c1OC)C(C)(C)C CHEMBL3924507 ED50 0.09 nM
CCCCCCO[C@@H](C)c1cccc(-c2csc(NC(=O)c3cc(Cl)c(/C=C(\C)C(=O)O)c(Cl)c3)n2)c1OC CHEMBL2107831 ED50 1.09 nM
CCCCCCO[C@H](C)c1cccc(-c2csc(NC(=O)c3cc(Cl)c(/C=C(\C)C(=O)O)c(Cl)c3)n2)c1OC CHEMBL3961997 ED50 1.4 nM
CCCCCC[C@H](OC)c1cccc(-c2csc(NC(=O)c3cc(Cl)c(/C=C(\C)C(=O)O)c(Cl)c3)n2)c1OC CHEMBL3959282 ED50 2.08 nM
CC1=NN(c2ccc3c(c2)CCC3)C(=O)/C1=C(/C)NNC(=S)N1CCc2cc(C(=O)O)ccc21 CHEMBL1257604 EC50 3.0 nM
CCCCCC[C@@H](OC)c1cccc(-c2csc(NC(=O)c3cc(Cl)c(/C=C(\C)C(=O)O)c(Cl)c3)n2)c1OC CHEMBL3910159 ED50 3.09 nM
C[C@@H]1CCCN1Cc1sc(NC(=O)c2cnc(N3CCC(C(=O)O)CC3)c(F)c2)nc1-c1cc(Cl)cs1 CHEMBL4648559 EC30 3.2 nM
CC1=NN(c2ccc(C)c(C)c2)C(=O)/C1=C(/C)NNC(=S)N1CCc2cc(C(=O)O)ccc21 CHEMBL1257603 EC50 6.0 nM
O=C(Nc1nc(-c2cccc(OC(F)(F)F)c2F)cs1)c1ccc(Nc2cc(N3CC(O)C3)ncn2)cc1 CHEMBL429295 EC50 7.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1ccc(Nc2cc(N3CC(O)C3)ncn2)cc1 CHEMBL248218 EC50 9.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1cc(Cl)c(N2CCC(C(=O)O)CC2)c(Cl)c1 CHEMBL455654 EC50 10.0 nM
CN(C)c1cc(Nc2ccc(C(=O)Nc3nc(-c4ccc(F)c(C(F)(F)F)c4)c(Cl)s3)cc2)ncn1 CHEMBL248390 EC50 11.0 nM
O=C(Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)ns1)c1ccc(Nc2cc(N3CC(O)C3)ncn2)cc1 CHEMBL249471 EC50 13.0 nM
Cc1[nH]n(-c2ccc(C(C)(C)C)cc2)c(=O)c1/N=N/c1c(O)cc(S(=O)(=O)O)c2ccccc12 CHEMBL3144775 EC50 20.0 nM
CCCCc1ccc(-c2ccc3c4c([nH]c3c2F)-c2ccc(NC(=O)C(=O)O)cc2C4)cc1 CHEMBL498173 EC50 21.0 nM
CN(CCO)c1cc(Nc2ccc(C(=O)Nc3nc(-c4cccc(C(F)(F)F)c4F)cs3)cc2)ncn1 CHEMBL440231 EC50 22.0 nM
CNC(=O)c1ccc2c(c1)CCN2C(=S)NN/C(C)=C1\C(=O)N(c2ccc(C)c(C)c2)N=C1C CHEMBL1257846 EC50 22.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1ccc(Nc2cc(N3CCC3)ncn2)cc1 CHEMBL248217 EC50 23.0 nM
CCCCc1ccc(-c2ccc3c4c([nH]c3c2F)-c2ccc(NC(C)=O)cc2C4)cc1 CHEMBL498581 EC50 25.0 nM
Cc1cc(-c2ccc3c4c([nH]c3c2F)-c2ccc(C(=O)O)cc2C4)ccc1F CHEMBL496123 EC50 26.0 nM
CCCCc1ccc(-c2ccc3c4c([nH]c3c2)-c2cc(O)c(C(=O)O)cc2CC4)cc1 CHEMBL479081 EC50 26.0 nM
CCNC(=O)c1ccc2c(c1)CCN2C(=S)NN/C(C)=C1\C(=O)N(c2ccc(C)c(C)c2)N=C1C CHEMBL1257962 EC50 26.0 nM
O=C(Nc1nc2c(s1)CCOc1c-2cccc1C(F)(F)F)c1ccc(Nc2ccncn2)cc1 CHEMBL245795 EC50 27.0 nM
O=C1NC(=O)/C(=C/c2ccc(C(=O)Nc3nc(-c4ccc(F)c(F)c4)cs3)cc2)S1 CHEMBL251095 EC50 28.0 nM
NC(=O)C1CCN(c2ncc(C(=O)Nc3nc(-c4cccc(C(F)(F)F)c4F)cs3)cc2Cl)CC1 CHEMBL462874 EC50 28.0 nM
CN(c1cc(Nc2ccc(C(=O)Nc3nc(-c4ccc(F)c(C(F)(F)F)c4)ns3)cc2)ncn1)C(CO)NO CHEMBL249672 EC50 29.0 nM
O=C(Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)ns1)c1ccc(Nc2cc(NCCO)ncn2)cc1 CHEMBL248428 EC50 30.0 nM
CC1=NN(c2ccc(C)c(C)c2)C(=O)/C1=C(/C)NNC(=S)N1CCc2cc(C(=O)N3CCOCC3)ccc21 CHEMBL1257847 EC50 31.0 nM
O=C(Nc1nc(-c2cccc(OC(F)(F)F)c2F)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL247606 EC50 32.0 nM
Nc1nc(-c2cccc(OC(F)(F)F)c2F)cs1 CHEMBL408853 EC50 32.0 nM
O=C(Nc1nc(-c2ccc(F)c(C(F)(F)F)c2F)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL247645 EC50 33.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1cnc(N2CCC(C(=O)O)CC2)c(Cl)c1 CHEMBL523975 EC50 33.0 nM
NS(=O)(=O)C1CCN(c2ncc(C(=O)Nc3nc(-c4cccc(C(F)(F)F)c4F)cs3)cc2Cl)CC1 CHEMBL516993 EC50 34.0 nM
CC(C)Cc1cccc(-c2csc(NC(=O)c3ccc(Nc4ccncn4)cc3)n2)c1F CHEMBL247041 EC50 35.0 nM
Cc1cc(-c2ccc3c4c([nH]c3c2)-c2cc(O)c(C(=O)O)cc2CC4)ccc1F CHEMBL477381 EC50 35.0 nM
CC1=NN(c2ccc3c(c2)CCC3)C(=O)/C1=C(/C)NNC(=S)N1CCCc2cc(C(=O)O)ccc21 CHEMBL1257724 EC50 35.0 nM
CCCc1ccc(-c2ccc3c4c([nH]c3c2F)-c2ccc(C(=O)O)cc2C4)cc1 CHEMBL496122 EC50 37.0 nM
COc1cc(Nc2ccc(C(=O)Nc3nc(-c4cccc(C(F)(F)F)c4F)cs3)cc2)ncn1 CHEMBL246847 EC50 38.0 nM
CC1=NN(c2ccc(C)c(C)c2)C(=O)/C1=N\Nc1cccc(-c2cccc(C(=O)O)c2)c1O CHEMBL461101 EC50 38.0 nM
Cc1[nH]n(-c2cccc(C(F)(F)F)c2)c(=O)c1/N=N/c1c(O)cc(S(=O)(=O)O)c2ccccc12 CHEMBL3144844 EC50 40.0 nM
Cc1ccc(-n2[nH]c(C)c(/N=N/c3c(O)cc(S(=O)(=O)O)c4ccccc34)c2=O)cc1C CHEMBL3144661 EC50 40.0 nM
CCCOc1ccc(-c2ccc3c4c([nH]c3c2)-c2cc(O)c(C(=O)O)cc2CC4)cc1 CHEMBL518285 EC50 41.0 nM
CC1=NN(c2ccc(C)c(C)c2)C(=O)/C1=C(/C)NNC(=O)N1CCc2cc(C(=O)O)ccc21 CHEMBL1257963 EC50 42.0 nM
Cc1cc(Nc2ccc(C(=O)Nc3nc(-c4cccc(C(F)(F)F)c4F)cs3)cc2)ncn1 CHEMBL245794 EC50 43.0 nM
CN(C)c1cc(Nc2ccc(C(=O)Nc3nc(-c4ccc(F)c(C(F)(F)F)c4)ns3)cc2)ncn1 CHEMBL247240 EC50 43.0 nM
C[C@H]1CN(c2ncc(C(=O)Nc3nc(-c4cccc(C(F)(F)F)c4F)cs3)cc2Cl)CC1C(=O)O CHEMBL461174 EC50 43.0 nM
CCCOc1cccc(-c2ccc3c4c([nH]c3c2)-c2cc(O)c(C(=O)O)cc2CC4)c1 CHEMBL479083 EC50 43.0 nM
C/C(NNC(=S)c1ccc(C(=O)O)cc1)=C1/C(=O)N(c2ccc(C)cc2)c2ccc(F)cc21 CHEMBL1222640 EC50 44.0 nM
Cc1sc(NC(=O)c2ccc(Nc3cc(N(C)C)ncn3)cc2)nc1-c1ccc(F)c(C(F)(F)F)c1 CHEMBL248389 EC50 45.0 nM
CC1=NN(c2ccc3c(c2)CCC3)C(=O)/C1=C(/C)NNC(=O)N1CCc2cc(C(=O)O)ccc21 CHEMBL1258074 EC50 46.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1cnc(N2CCC(C(=O)O)CC2)c(Br)c1 CHEMBL459474 EC50 50.0 nM
CCCCc1ccc(-c2ccc3cc(-c4ccc(C(=O)O)c(O)c4)[nH]c3c2F)cc1 CHEMBL522070 EC50 51.0 nM
CCCCc1cccc(-c2csc(NC(=O)c3ccc(Nc4ccncn4)cc3)n2)c1F CHEMBL247040 EC50 53.0 nM
CN(C)c1cc(Nc2ccc(C(=O)Nc3nc(-c4cccc(C(F)(F)F)c4F)cs3)cc2)ncn1 CHEMBL247017 EC50 54.0 nM
CCCCc1ccc(-c2ccc3c4c([nH]c3c2F)-c2ccc(C(=O)O)cc2CC4)cc1 CHEMBL477400 EC50 55.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1ccc(N2CCC(C(=O)O)CC2)c(Cl)c1 CHEMBL459687 EC50 56.0 nM
Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1 CHEMBL263109 EC50 57.0 nM
C[C@@H](Nc1ncc(C(=O)Nc2nc(-c3cccc(C(F)(F)F)c3F)cs2)cc1Cl)C(=O)O CHEMBL524116 EC50 57.0 nM
CC(C)Cc1cc(-c2nc(NC(=O)c3cnc(N4CCC(C(=O)O)CC4)c(Cl)c3)sc2F)ccc1F CHEMBL1170197 EC50 58.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL428226 EC50 60.0 nM
CC1=NN(c2ccc(C)c(C)c2)C(=O)/C1=C(/C)NNC(=S)N1CCCc2cc(C(=O)O)ccc21 CHEMBL1257723 EC50 64.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1ccc(Nc2cc(NCCO)ncn2)cc1 CHEMBL248041 EC50 65.0 nM
Cc1ccc(-c2ccc3c4c([nH]c3c2)-c2cc(O)c(C(=O)O)cc2CC4)cc1C CHEMBL477174 EC50 65.0 nM
Cc1sc(NC(=O)c2cnc(N3CCC(C(=O)O)CC3)c(Cl)c2)nc1-c1ccc(F)c(C(F)(F)F)c1 CHEMBL1172354 EC50 66.0 nM
Cc1cc(C)cc(-c2ccc3c4c([nH]c3c2)-c2cc(O)c(C(=O)O)cc2CC4)c1 CHEMBL477175 EC50 67.0 nM
Cc1[nH]n(-c2ccc(C(C)C)cc2)c(=O)c1/N=N/c1c(O)cc(S(=O)(=O)O)c2ccccc12 CHEMBL3144783 EC50 70.0 nM
Cc1[nH]n(-c2cccc(C(C)(C)C)c2)c(=O)c1/N=N/c1c(O)cc(S(=O)(=O)O)c2ccccc12 CHEMBL3144778 EC50 70.0 nM
O=S(=O)(O)c1cc(O)c(/N=N/c2ccc3ccccc3c2O)c2ccccc12 CHEMBL420168 EC50 70.0 nM
O=C(Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)ns1)c1ccc(Nc2cc(N(CCCO)CCCO)ncn2)cc1 CHEMBL442278 EC50 71.0 nM
CCCCc1ccc(-c2ccc3c4c([nH]c3c2)-c2ccc(C(N)=O)cc2CC4)cc1 CHEMBL516272 EC50 76.0 nM
O=C(Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)ns1)c1ccc(Nc2cc(N3CCC3)ncn2)cc1 CHEMBL246429 EC50 81.0 nM
C/C(NNC(=S)c1ccc(C(=O)O)cc1)=C1/C(=O)N(c2ccc(C)c(C)c2)c2ccccc21 CHEMBL1222569 EC50 82.0 nM
O=C(Nc1nc(-c2ccc(F)c(F)c2F)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL393087 EC50 84.0 nM
COCCN(C)c1cc(Nc2ccc(C(=O)Nc3nc(-c4cccc(C(F)(F)F)c4F)cs3)cc2)ncn1 CHEMBL248042 EC50 84.0 nM
CCCCc1ccc(-c2ccc3c4c([nH]c3c2)-c2ccc(C(N)=O)cc2C4)cc1 CHEMBL496950 EC50 86.0 nM
O=C(Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)c(Cl)s1)c1cnc(N2CCC(C(=O)O)CC2)c(Cl)c1 CHEMBL1172355 EC50 86.0 nM
O=C(Nc1nc(-c2ccc(C(F)(F)F)c(F)c2F)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL247644 EC50 87.0 nM
Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)c(F)s1 CHEMBL405683 EC50 89.0 nM
O=C(Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)c(F)s1)c1cnc(N2CCC(C(=O)O)CC2)c(Cl)c1 CHEMBL1170611 EC50 89.0 nM
Cc1ccc(-n2[nH]cc(/N=N/c3c(O)cc(S(=O)(=O)O)c4ccccc34)c2=O)cc1C CHEMBL3144666 EC50 100.0 nM
Cc1[nH]n(-c2ccc(C(F)(F)F)cc2)c(=O)c1/N=N/c1c(O)cc(S(=O)(=O)O)c2ccccc12 CHEMBL3144784 EC50 100.0 nM
O=C(Nc1nc(-c2cccc(Br)c2F)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL249063 EC50 100.0 nM
O=C(Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL247822 EC50 100.0 nM
Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)cs1 CHEMBL260846 EC50 100.0 nM
O=C(Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)cs1)c1cnc(N2CCC(C(=O)O)CC2)c(Cl)c1 CHEMBL1171610 EC50 100.0 nM
C/C(NNC(=S)c1ccc(C(=O)O)cc1)=C1/C(=O)N(c2ccc(C)c(C)c2)c2ccc(F)cc21 CHEMBL1222641 EC50 103.0 nM
Cc1ccc(-c2ccc3c4c([nH]c3c2)-c2cc(O)c(C(=O)O)cc2CC4)cc1 CHEMBL489367 EC50 109.0 nM
CCCCc1ccc(-c2ccc3c4c([nH]c3c2)-c2ccc(C(=O)O)cc2CC4)cc1 CHEMBL477195 EC50 111.0 nM
CCCCc1ccc(-c2ccc3c4c([nH]c3c2F)-c2ccc(C(=O)O)cc2C4(C)C)cc1 CHEMBL525732 EC50 111.0 nM
CCCCc1ccc(-c2ccc3c(C)c(-c4ccc(C(=O)O)c(O)c4)[nH]c3c2F)cc1 CHEMBL496755 EC50 116.0 nM
CCCCc1ccc(-c2ccc3cc(-c4ccc(C(=O)O)cc4)[nH]c3c2F)cc1 CHEMBL525533 EC50 117.0 nM
CCCCc1ccc(-c2ccc3c4c([nH]c3c2)-c2ccc(-c3nnn[nH]3)cc2CC4)cc1 CHEMBL477401 EC50 119.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1ccc(Nc2ccnnc2)cc1 CHEMBL247016 EC50 120.0 nM
CCCCc1ccc(-c2ccc3c4c([nH]c3c2)-c2ccc(C(=O)N(C)C)cc2CC4)cc1 CHEMBL479093 EC50 127.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1cnc(N2CCNC(C(=O)O)C2)c(Cl)c1 CHEMBL490096 EC50 129.0 nM
CCNc1cc(Nc2ccc(C(=O)Nc3nc(-c4cccc(C(F)(F)F)c4F)cs3)cc2)ncn1 CHEMBL247019 EC50 130.0 nM
COCCN(C)c1cc(Nc2ccc(C(=O)Nc3nc(-c4ccc(F)c(C(F)(F)F)c4)ns3)cc2)ncn1 CHEMBL246428 EC50 130.0 nM
CCCc1sc(NC(=O)c2cnc(N3CCC(C(=O)O)CC3)c(Cl)c2)nc1-c1ccc(F)c(C(F)(F)F)c1 CHEMBL1171784 EC50 130.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1cnc(N2CCC(C(=O)O)CC2)c(C(F)(F)F)c1 CHEMBL461974 EC50 134.0 nM
N#Cc1cc(C(=O)Nc2nc(-c3cccc(C(F)(F)F)c3F)cs2)cnc1N1CCC(C(=O)O)CC1 CHEMBL461975 EC50 138.0 nM
O=C(Nc1nc2c(s1)COc1c-2cccc1C(F)(F)F)c1ccc(Nc2ccncn2)cc1 CHEMBL399357 EC50 140.0 nM
CCc1cccc(-c2csc(NC(=O)c3ccc(Nc4ccncn4)cc3)n2)c1F CHEMBL395701 EC50 143.0 nM
O=C(O)c1cc2ccc3c4ccc(C(F)(F)F)cc4[nH]c3c2cc1O CHEMBL491798 EC50 143.0 nM
O=C(O)c1cc2c(cc1O)-c1[nH]c3cc(-c4cccc(C(F)(F)F)c4)ccc3c1CC2 CHEMBL515795 EC50 148.0 nM
C[C@@H]1CCCN1Cc1sc(NC(=O)c2cnc(N3CCC(C(=O)O)CC3)cn2)nc1-c1cc(Cl)cc(C(F)(F)F)c1 CHEMBL4643277 EC30 150.0 nM
CCCCc1ccc(-c2ccc3c4c([nH]c3c2)-c2ccc(C(=O)O)cc2C4)cc1 CHEMBL525906 EC50 160.0 nM
CCCCc1ccc(-c2ccc3cc(-c4ccc(C(N)=O)cc4)[nH]c3c2F)cc1 CHEMBL497793 EC50 160.0 nM
CCc1sc(NC(=O)c2cnc(N3CCC(C(=O)O)CC3)c(Cl)c2)nc1-c1ccc(F)c(C(F)(F)F)c1 CHEMBL1171783 EC50 160.0 nM
O=C(Nc1nc(-c2ccc(F)cc2F)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL247431 EC50 170.0 nM
CCCCc1ccc(-c2ccc3nc(-c4ccc(C(=O)O)c(O)c4)[nH]c3c2)cc1 CHEMBL497349 EC50 179.0 nM
Cc1sc(NC(=O)c2ccc(Nc3ccncn3)cc2)nc1-c1ccc(F)c(C(F)(F)F)c1 CHEMBL248388 EC50 180.0 nM
Cc1sc(N)nc1-c1ccc(F)c(C(F)(F)F)c1 CHEMBL258532 EC50 180.0 nM
Cc1cccc(-c2ccc3c4c([nH]c3c2)-c2cc(O)c(C(=O)O)cc2CC4)c1 CHEMBL521746 EC50 194.0 nM
Cc1[nH]n(-c2ccc(OCc3ccccc3)cc2)c(=O)c1/N=N/c1c(O)cc(S(=O)(=O)O)c2ccccc12 CHEMBL3144672 EC50 200.0 nM
O=S(=O)(O)c1cc(O)c(/N=N/c2c(O)c3ccccc3c3ccccc23)c2ccccc12 CHEMBL124367 EC50 200.0 nM
Cc1[nH]n(-c2ccc(Cl)c(Cl)c2)c(=O)c1/N=N/c1c(O)cc(S(=O)(=O)O)c2ccccc12 CHEMBL3144664 EC50 200.0 nM
O=S(=O)(O)c1cc(O)c(/N=N/c2c(O)ccc3ccccc23)c2ccccc12 CHEMBL124855 EC50 200.0 nM
CC(C)(C)OC(=O)c1[nH]n(-c2ccc(C(C)(C)C)cc2)c(=O)c1/N=N/c1c(O)cc(S(=O)(=O)O)c2ccccc12 CHEMBL3144680 EC50 200.0 nM
CN(CCO)c1cc(Nc2ccc(C(=O)Nc3nc(-c4ccc(F)c(C(F)(F)F)c4)ns3)cc2)ncn1 CHEMBL248434 EC50 220.0 nM
CCCCc1cc(-c2nc(NC(=O)c3cnc(N4CCC(C(=O)O)CC4)c(Cl)c3)sc2F)ccc1F CHEMBL1170004 EC50 220.0 nM
CCCCc1ccc(-c2ccc3c(CC)c(-c4ccc(C(=O)O)c(O)c4)[nH]c3c2F)cc1 CHEMBL495731 EC50 228.0 nM
O=C(Nc1nc(-c2ccc(Cl)cc2F)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL393268 EC50 230.0 nM
Cc1cccc(C)c1-c1ccc2c3c([nH]c2c1)-c1cc(O)c(C(=O)O)cc1CC3 CHEMBL492017 EC50 232.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)n2)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL248192 EC50 244.0 nM
Cc1cc(C(=O)Nc2nc(-c3cccc(C(F)(F)F)c3F)cs2)cnc1N1CCC(C(=O)O)CC1 CHEMBL462144 EC50 253.0 nM
O=C(Nc1nc(-c2ccc(C(F)(F)F)cc2F)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL428227 EC50 259.0 nM
Nc1nc(-c2ccc(C(F)(F)F)cc2F)cs1 CHEMBL405478 EC50 260.0 nM
Cc1cc(-c2ccc3c4c([nH]c3c2F)-c2ccc(C(N)=O)cc2C4)ccc1F CHEMBL522391 EC50 277.0 nM
O=C(Nc1nc(-c2cccc(OC(F)(F)F)c2)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL245993 EC50 280.0 nM
CN(C)c1ccc(-c2ccc3c4c([nH]c3c2)-c2cc(O)c(C(=O)O)cc2CC4)cc1 CHEMBL476556 EC50 284.0 nM
O=C(Nc1nc(-c2ccc(C(F)(F)F)c(F)c2)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL247643 EC50 288.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1cnc(N2CCCC(C(=O)O)C2)c(Cl)c1 CHEMBL489309 EC50 294.0 nM
Cc1ccc(-n2[nH]c(C(C)(C)C)c(/N=N/c3c(O)cc(S(=O)(=O)O)c4ccccc34)c2=O)cc1C CHEMBL3144670 EC50 300.0 nM
Cc1[nH]n(-c2cccc([N+](=O)[O-])c2)c(=O)c1/N=N/c1c(O)cc(S(=O)(=O)O)c2ccccc12 CHEMBL3144781 EC50 300.0 nM
COc1ccc2ccc(O)c(/N=N/c3c(O)cc(S(=O)(=O)O)c4ccccc34)c2c1 CHEMBL123373 EC50 300.0 nM
Cc1[nH]n(-c2ccc(I)cc2)c(=O)c1/N=N/c1c(O)cc(S(=O)(=O)O)c2ccccc12 CHEMBL3144662 EC50 300.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1ccc(Nc2cncnc2)cc1 CHEMBL246843 EC50 320.0 nM
O=C(O)c1cc2c(cc1O)-c1[nH]c3ccc(C(F)(F)F)cc3c1CC2 CHEMBL523460 EC50 333.0 nM
O=C(Nc1nc(-c2ccc(Cl)c(Cl)c2)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL391597 EC50 347.0 nM
C[C@@H]1CCCN1Cc1sc(NC(=O)c2cnc(N3CCC(C(=O)O)CC3)cn2)nc1-c1cc(Cl)cs1 CHEMBL4637773 EC30 350.0 nM
O=C(O)c1cc2c(cc1O)-c1[nH]c3cc(-c4ccccc4)ccc3c1CC2 CHEMBL489365 EC50 373.0 nM
CCCCc1ccc(-c2ccc3c4c([nH]c3c2F)-c2cc(NC(C)=O)c(C(=O)O)cc2C4)cc1 CHEMBL497149 EC50 376.0 nM
Cc1[nH]n(-c2ccc([N+](=O)[O-])cc2)c(=O)c1/N=N/c1c(O)cc(S(=O)(=O)O)c2ccccc12 CHEMBL3144682 EC50 400.0 nM
O=C(Nc1nc(-c2ccc(F)c(F)c2)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL247642 EC50 400.0 nM
O=C(Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)cs1)c1ccc(Nc2ccnnc2)cc1 CHEMBL438874 EC50 400.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1ccc(Nc2ccncc2)cc1 CHEMBL248211 EC50 400.0 nM
O=C(Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)ns1)c1ccc(Nc2ccncn2)cc1 CHEMBL248053 EC50 410.0 nM
O=C(Nc1nc(-c2cccc(F)c2F)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL249061 EC50 415.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL246619 EC50 418.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1ccc(N2CCC(C(=O)O)CC2)nc1 CHEMBL523097 EC50 430.0 nM
CCCCc1ccc(-c2ccc3c4c([nH]c3c2)-c2ccc(C(=O)O)cc2S(=O)(=O)C4)cc1 CHEMBL497372 EC50 449.0 nM
COCc1ccc(-c2ccc3c4c([nH]c3c2)-c2cc(O)c(C(=O)O)cc2CC4)cc1 CHEMBL479082 EC50 452.0 nM
O=C(O)c1cc2c(cc1O)-c1[nH]c3cc(C(F)(F)F)ccc3c1CC2 CHEMBL490585 EC50 473.0 nM
O=C(Nc1nc(-c2ccc(F)c(Cl)c2)c(F)s1)c1cnc(N2CCC(C(=O)O)CC2)c(Cl)c1 CHEMBL1172356 EC50 480.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1cnc(N2CCC(c3nn[nH]n3)CC2)c(Cl)c1 CHEMBL518057 EC50 485.0 nM
O=C(Nc1nc(-c2ccc(C(F)(F)F)cc2)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL248237 EC50 490.0 nM
Cc1[nH]n(-c2ccc(F)cc2)c(=O)c1/N=N/c1c(O)cc(S(=O)(=O)O)c2ccccc12 CHEMBL3144776 EC50 500.0 nM
O=C(Nc1nc(-c2ccc(Cl)cc2Cl)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL247818 EC50 510.0 nM
O=C(Nc1nc2c(s1)COc1ccccc1-2)c1ccc(Nc2ccncn2)cc1 CHEMBL409504 EC50 520.0 nM
O=C(Nc1nc2c(s1)COc1c(Cl)cccc1-2)c1ccc(Nc2ccncn2)cc1 CHEMBL409092 EC50 530.0 nM
Cc1sc(NC(=O)c2ccc(Nc3ccncn3)cc2)nc1-c1cccc(C(F)(F)F)c1F CHEMBL399356 EC50 540.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1ccc(Nc2ncncn2)cc1 CHEMBL248039 EC50 540.0 nM
Cc1sc(N)nc1-c1cccc(C(F)(F)F)c1F CHEMBL405203 EC50 540.0 nM
O=C(Nc1nc(-c2ccc(F)cc2F)cs1)c1ccc(Nc2ccnnc2)cc1 CHEMBL247015 EC50 550.0 nM
O=C(Nc1nc(-c2ccc(Cl)cc2)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL399136 EC50 568.0 nM
O=C(O)c1cc2c(cc1O)-c1[nH]c3ccc(-c4ccccc4)cc3c1CC2 CHEMBL521768 EC50 569.0 nM
O=C(Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)ns1)c1cnc(N2CCC(C(=O)O)CC2)c(Cl)c1 CHEMBL1169647 EC50 574.0 nM
CCOc1nn(-c2ccc(C)c(C)c2)c(O)c1/N=N/c1c(O)cc(S(=O)(=O)O)c2ccccc12 CHEMBL121918 EC50 600.0 nM
O=C(Nc1nc(-c2cccc(Cl)c2F)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL249062 EC50 610.0 nM
O=C(Nc1nc(-c2ccc(F)c(OC(F)(F)F)c2)c(F)s1)c1cnc(N2CCC(C(=O)O)CC2)c(Cl)c1 CHEMBL1170600 EC50 620.0 nM
O=C(Nc1nc(-c2cccc(Br)c2)cs1)c1ccc(Nc2ccncn2)cc1 CHEMBL246618 EC50 640.0 nM
O=C(Nc1nc(-c2ccc(F)c(Br)c2)c(F)s1)c1cnc(N2CCC(C(=O)O)CC2)c(Cl)c1 CHEMBL1170598 EC50 670.0 nM
Cc1cccc(-n2[nH]c(C)c(/N=N/c3c(O)cc(S(=O)(=O)O)c4ccccc34)c2=O)c1 CHEMBL3144786 EC50 700.0 nM
Nc1nc(-c2cccc(C(F)(F)F)c2F)c(F)s1 CHEMBL262855 EC50 700.0 nM
O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)c(F)s1)c1cnc(N2CCC(C(=O)O)CC2)c(Cl)c1 CHEMBL1171609 EC50 702.0 nM
CC(C)(C)c1ccc(-c2ccc(-c3nc4cc(/C=C5\SC(=S)NC5=O)ccc4[nH]3)o2)cc1 CHEMBL206304 EC50 720.0 nM
O=C(Nc1nc(-c2ccc(F)c(F)c2)ns1)c1ccc(Nc2ccncn2)cc1 CHEMBL248047 EC50 720.0 nM
Cc1ccc(-c2csc(-c3nc4cc(/C=C5\SC(=S)NC5=O)ccc4[nH]3)c2)cc1C CHEMBL204160 EC50 780.0 nM
Cc1ccc(-c2csc(NC(=O)c3ccc(Nc4ccncn4)cc3)n2)cc1C CHEMBL248004 EC50 784.0 nM
O=C(O)c1cc2c(cc1O)-c1[nH]c3c(F)ccc(C(F)(F)F)c3c1CC2 CHEMBL490586 EC50 799.0 nM
Cc1ccc2c(c1)[nH]c1c3cc(O)c(C(=O)O)cc3ccc21 CHEMBL489388 EC50 870.0 nM
Cc1ccc(-n2[nH]c(-c3ccccc3)c(/N=N/c3c(O)cc(S(=O)(=O)O)c4ccccc34)c2=O)cc1C CHEMBL3144790 EC50 900.0 nM
CC(C)(C)c1ccc(-c2cccc(-c3nc4cc(/C=C5\SC(=S)NC5=O)ccc4[nH]3)c2)cc1 CHEMBL382806 EC50 900.0 nM
O=C(Nc1nc(-c2ccc(F)c(OCC(F)(F)F)c2)c(F)s1)c1cnc(N2CCC(C(=O)O)CC2)c(Cl)c1 CHEMBL1169816 EC50 950.0 nM
O=C(Nc1nc(-c2cccc(OC(F)(F)F)c2F)ns1)c1ccc(Nc2ccncn2)cc1 CHEMBL248055 EC50 970.0 nM
Cc1ccc(-n2[nH]c(C)c(/N=N/c3c(O)cc(C(=O)O)c4ccccc34)c2=O)cc1C CHEMBL3144677 EC50 1000.0 nM
O=C1NC(=S)S/C1=C\c1ccc2[nH]c(-c3cccc(-c4ccc(Cl)c(Cl)c4)n3)nc2c1 CHEMBL204667 EC50 1000.0 nM
CC(C)(C)c1ccc(-c2cccc(-c3nc4cc(/C=C5\SC(=S)NC5=O)ccc4[nH]3)c2O)cc1 CHEMBL205027 EC50 1000.0 nM