Nc1cc([C@H](CCN[C@H]2C[C@@H](c3ccccc3)c3ccccc32)c2ccccc2)c2nn[nH]c2n1 CHEMBL4747269 IC50 1.0 nM
Nc1cc([C@H](CCNC23CCC(c4ccccc4)(CC2)CC3)c2ccccc2)c2nn[nH]c2n1 CHEMBL4790231 IC50 1.0 nM
NC(c1ccccc1)c1ccccc1Cn1c(=S)[nH]c(=O)c2[nH]ccc21 CHEMBL5197968 pIC50 1.259 nM
C[C@@H](N)c1cc(Cl)ccc1Cn1c(=S)[nH]c(=O)c2[nH]ccc21 CHEMBL5095218 IC50 1.5 nM
Nc1cc([C@H](CCN[C@H]2CC[C@H](c3ccccc3)CC2)c2ccccc2)c2nn[nH]c2n1 CHEMBL4763667 IC50 2.0 nM
Nc1cc([C@H](CCN[C@@H]2CC[C@@H](c3ccccc3)c3ccccc32)c2ccccc2)c2nn[nH]c2n1 CHEMBL4752248 IC50 2.9 nM
NCCSCCc1c[nH]c2c(F)cccc12 CHEMBL2347170 IC50 3.0 nM
C[C@@H](N)c1cc(Cl)ccc1Cn1c(=S)[nH]c(=O)c2[nH]cnc21 CHEMBL5181350 IC50 3.6 nM
NCCSCCc1c[nH]c2ccc(F)cc12 CHEMBL2347168 IC50 4.0 nM
Nc1cc(SCc2c(Cl)cccc2Cl)c2nn[nH]c2n1 CHEMBL4548537 IC50 4.6 nM
NCCCCCc1c[nH]c2ccc(F)cc12 CHEMBL1630742 IC50 5.0 nM
N#CSCCCc1c[nH]c2ccc(F)cc12 CHEMBL2347177 IC50 5.0 nM
O=C(NO)c1c[nH]c(NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)nc1=O CHEMBL4068067 IC50 5.0 nM
Nc1cc([C@H](CCN(CCF)C23CCC(c4ccccc4)(CC2)CC3)c2ccccc2)c2nn[nH]c2n1 CHEMBL4740830 IC50 5.0 nM
Nc1cc([C@H]2CCN[C@H]3C[C@H](Cc4ccccc4)[C@@H](C3)Oc3cccc(c3)Cn3cc2cn3)c2nn[nH]c2n1 CHEMBL4861370 IC50 5.0 nM
NCCCCc1c[nH]c2c(F)cccc12 CHEMBL2347032 IC50 6.0 nM
CN(CC[C@H](c1ccccc1)c1cc(N)nc2[nH]nnc12)C12CCC(c3ccccc3)(CC1)CC2 CHEMBL4782307 IC50 6.0 nM
Nc1cc(OCc2c(Cl)cccc2Cl)c2nn[nH]c2n1 CHEMBL4453728 IC50 6.7 nM
Nc1cc(SCc2ccccc2F)c2nn[nH]c2n1 CHEMBL4482878 IC50 6.8 nM
Nc1cc(C2CCNC34CCC(c5ccccc5)(CC3)[C@H](C4)Oc3cccc(c3)Cn3cc2cn3)c2nn[nH]c2n1 CHEMBL4851535 IC50 7.0 nM
NCCCCc1c[nH]c2ccc(F)cc12 CHEMBL1630741 IC50 8.0 nM
Nc1cc(C2CCNCc3cccc(c3)OCc3cccc(c3)Cn3cc2cn3)c2nn[nH]c2n1 CHEMBL4878307 IC50 8.0 nM
Nc1cc(SCc2nn(-c3ccccc3)nc2C(F)F)c2nn[nH]c2n1 CHEMBL4594116 IC50 8.5 nM
O=c1[nH]c(=S)n(C[C@H]2CCCO2)c2nc[nH]c12 CHEMBL4278946 IC50 9.0 nM
Nc1cc(C(CCNC23CCC(c4ccccc4)(CC2)OC3)c2ccccc2)c2nn[nH]c2n1 CHEMBL4751166 IC50 9.3 nM
OCCNCCCc1c[nH]c2ccc(F)cc12 CHEMBL2347167 IC50 10.0 nM
OCCNCCc1c[nH]c2ccc(F)cc12 CHEMBL2347166 IC50 10.0 nM
ONCCCc1c[nH]c2ccc(F)cc12 CHEMBL2347176 IC50 11.0 nM
Nc1cc(OCc2nn(-c3ccccc3)nc2C(F)F)c2nn[nH]c2n1 CHEMBL4531688 IC50 12.0 nM
CN[C@H](C)c1cc(Cl)ccc1Cn1c(=S)[nH]c(=O)c2[nH]ccc21 CHEMBL5200126 IC50 12.7 nM
Fc1ccc2[nH]cc(CCCNCc3ccccc3)c2c1 CHEMBL2347165 IC50 13.0 nM
CCN(CCc1c[nH]c2ccc(F)cc12)S(C)(=O)=O CHEMBL2346670 IC50 14.0 nM
Nc1cc(C2CCNCCc3cccc(c3)Oc3cccc(c3)Cn3cc2cn3)c2nn[nH]c2n1 CHEMBL4877383 IC50 14.0 nM
Nc1cc([C@H](CCN[C@@H]2CC[C@@H](c3ccccc3)C2)c2ccccc2)c2nn[nH]c2n1 CHEMBL4795827 IC50 15.0 nM
NCc1cc(Cl)ccc1Cn1c(=S)[nH]c(=O)c2[nH]ccc21 CHEMBL5172456 IC50 15.0 nM
O=c1[nH]c(=S)n(Cc2ccccc2CN2CCC2)c2cc[nH]c12 CHEMBL5185576 IC50 15.1 nM
CNCc1cc(Cl)ccc1Cn1c(=S)[nH]c(=O)c2[nH]ccc21 CHEMBL5205410 IC50 15.9 nM
Nc1cc(Cc2cccc(Cl)c2)c2nn[nH]c2n1 CHEMBL4776850 IC50 16.0 nM
CCCCNCCCc1c[nH]c2ccc(F)cc12 CHEMBL1630737 IC50 17.0 nM
N#Cc1cccc(Cc2cc(N)nc3[nH]nnc23)c1 CHEMBL4780886 IC50 17.0 nM
COC(=O)c1cccc(Cc2cc(N)nc3[nH]nnc23)c1 CHEMBL4764237 IC50 17.0 nM
Nc1cc(C2CCNCCc3cccc(c3)OCc3cccc(c3)Cn3cc2cn3)c2nn[nH]c2n1 CHEMBL4859595 IC50 17.0 nM
NC(=O)CCCc1c[nH]c2ccc(F)cc12 CHEMBL2347181 IC50 18.0 nM
Fc1ccc([C@@H]2CCNC[C@H]2COc2ccc3c(c2)OCO3)cc1 CHEMBL490 IC50 20.0 nM
Nc1cc([C@H](CCCN2CCC(c3ccccc3)CC2)c2ccccc2)c2nn[nH]c2n1 CHEMBL4755252 IC50 20.0 nM
NCCSCCCc1c[nH]c2ccc(F)cc12 CHEMBL2347169 IC50 21.0 nM
Cn1ccc(-c2cccc(COc3cc(N)nc4[nH]nnc34)c2)n1 CHEMBL4443052 IC50 21.0 nM
Nc1cc(OCc2cccc(-c3cccc(F)c3)c2)c2nn[nH]c2n1 CHEMBL4456829 IC50 21.0 nM
Nc1cc(OCc2cccc(Cl)c2)c2nn[nH]c2n1 CHEMBL4463704 IC50 21.0 nM
Nc1cc(C2CCNCCc3cccc(c3)-c3cccc(c3)Cn3cc2cn3)c2nn[nH]c2n1 CHEMBL4853523 IC50 21.0 nM
Fc1ccc2[nH]cc(CCCN3CCN(c4ccccc4)CC3)c2c1 CHEMBL2347034 IC50 22.0 nM
Cc1c(COc2cc(N)nc3[nH]nnc23)cccc1-c1cccc(F)c1 CHEMBL4529431 IC50 23.0 nM
NC(=O)CCCc1c[nH]c2c(F)cccc12 CHEMBL2347024 IC50 24.0 nM
NCCCc1c[nH]c2c(F)cccc12 CHEMBL2347030 IC50 24.0 nM
Nc1cc(OCc2cc(-c3cccc(F)c3)ccc2Cl)c2nn[nH]c2n1 CHEMBL4582838 IC50 24.0 nM
O=C(NO)c1ccc(Cc2ccccc2)cc1O CHEMBL4096954 IC50 25.0 nM
Nc1cc(Cc2ccccc2)c2nn[nH]c2n1 CHEMBL4753981 IC50 25.0 nM
Nc1cc(C2CCNCc3cccc(c3)COc3cccc(c3)Cn3cc2cn3)c2nn[nH]c2n1 CHEMBL4877615 IC50 25.0 nM
CNCCCc1c[nH]c2ccc(F)cc12 CHEMBL1630734 IC50 26.0 nM
NCC(N)CCc1c[nH]c2ccc(F)cc12 CHEMBL2347178 IC50 26.0 nM
Cc1c(COc2cc(N)nc3[nH]nnc23)cccc1-c1ccn(C)n1 CHEMBL4466985 IC50 26.0 nM
Nc1cc(OCc2ccc(Cl)cc2)c2nn[nH]c2n1 CHEMBL4468646 IC50 26.0 nM
Nc1cc(OCc2ccccc2-n2cccn2)c2nn[nH]c2n1 CHEMBL4547081 IC50 26.0 nM
Nc1cc(OCc2ccccc2Cl)c2nn[nH]c2n1 CHEMBL4545748 IC50 26.0 nM
Nc1cc(Cc2ccn(Cc3cccc(Oc4cccc5c4CNC5)c3)n2)c2nn[nH]c2n1 CHEMBL4860429 IC50 26.0 nM
Nc1cc(C2CCNCC3(CCCC3)COc3cccc(c3)Cn3cc2cn3)c2nn[nH]c2n1 CHEMBL4848170 IC50 26.0 nM
C[C@H](N)c1cc(Cl)ccc1Cn1c(=S)[nH]c(=O)c2[nH]ccc21 CHEMBL5200597 IC50 26.4 nM
CCN(CCCc1c[nH]c2ccc(F)cc12)S(C)(=O)=O CHEMBL2347175 IC50 27.0 nM
Cc1nn(-c2ccccc2)nc1COc1cc(N)nc2[nH]nnc12 CHEMBL4586955 IC50 27.0 nM
CNCc1ccc(Cl)cc1Cn1c(=S)[nH]c(=O)c2[nH]ccc21 CHEMBL5186129 IC50 27.1 nM
NCCc1c[nH]c2c(F)cccc12 CHEMBL205229 IC50 28.0 nM
Nc1cc([C@H](CCN[C@@H]2CC[C@@H](c3ccccc3)OC2)c2ccccc2)c2nn[nH]c2n1 CHEMBL4776151 IC50 28.0 nM
Nc1cc(C2CCNCC(=O)N(CCc3ccccc3)Cc3cccc(c3)Cn3cc2cn3)c2nn[nH]c2n1 CHEMBL4846219 IC50 29.0 nM
Nc1cc(OCc2ccccc2F)c2nn[nH]c2n1 CHEMBL4467903 IC50 30.0 nM
NCc1ccc(-n2cc(-c3ccc4cc[nH]c4c3)c(C(F)(F)F)n2)cc1 CHEMBL4641455 IC50 30.0 nM
CC(C)NCc1ccccc1Cn1c(=S)[nH]c(=O)c2[nH]ccc21 CHEMBL5182747 IC50 30.9 nM
Nc1cc(C2CCNC3CCC(CC3)COc3cccc(c3)Cn3cc2cn3)c2nn[nH]c2n1 CHEMBL4863595 IC50 31.0 nM
O=c1[nH]c(=S)n(Cc2ccc(F)cc2)c2nc[nH]c12 CHEMBL5200638 pIC50 31.62 nM
Nc1cc(Cc2ccccc2F)c2nn[nH]c2n1 CHEMBL4798810 IC50 32.0 nM
NC(=O)CCc1c[nH]c2ccc(F)cc12 CHEMBL2347025 IC50 34.0 nM
NC(=O)CCCCc1c[nH]c2c(F)cccc12 CHEMBL2347027 IC50 34.0 nM
CC(C)(C)CNCc1cc(Cl)ccc1Cn1c(=S)[nH]c(=O)c2[nH]ccc21 CHEMBL5197383 IC50 35.0 nM
Nc1cc(OCc2ccccc2)c2nn[nH]c2n1 CHEMBL4530093 IC50 36.0 nM
Nc1cc(C2CCNCc3cccc(c3)Oc3cccc(c3)Cn3cc2cn3)c2nn[nH]c2n1 CHEMBL4877254 IC50 36.0 nM
CC(C)NCc1ccccc1Cn1c(=S)[nH]c(=O)c2[nH]cnc21 CHEMBL5181827 IC50 38.6 nM
NC(=O)CCCCc1c[nH]c2ccc(F)cc12 CHEMBL2347026 IC50 39.0 nM
Nc1cc(Cc2ccn(Cc3cccc(Cc4ccccc4)c3)n2)c2nn[nH]c2n1 CHEMBL4878518 IC50 39.0 nM
CNCc1c(Cl)cccc1Cn1c(=S)[nH]c(=O)c2[nH]ccc21 CHEMBL5207346 IC50 39.3 nM
Fc1ccc2[nH]cc(CCN3CCCC3)c2c1 CHEMBL1630731 IC50 40.0 nM
CNC(=O)CCCc1c[nH]c2ccc(F)cc12 CHEMBL2347028 IC50 40.0 nM
Cc1nc(N=C(N)N)nc2cc(F)ccc12 CHEMBL4080413 IC50 40.0 nM
Nc1nc(OCc2cccc(F)c2)c2nn[nH]c2n1 CHEMBL4292554 IC50 40.0 nM
COc1ccc2c(C)nc(NC(=N)N)nc2c1 CHEMBL581893 IC50 44.0 nM
Nc1cc(Cc2ccn(Cc3cccc(Oc4ccccc4)c3)n2)c2nn[nH]c2n1 CHEMBL4862053 IC50 44.0 nM
Nc1cc(Cc2ccn(Cc3cccc(O[C@H]4CCNC4)c3)n2)c2nn[nH]c2n1 CHEMBL4877407 IC50 46.0 nM
Nc1nc(OCc2ccc(F)cc2)c2nn[nH]c2n1 CHEMBL4280820 IC50 47.0 nM
CN(C)CCCc1c[nH]c2ccc(F)cc12 CHEMBL361949 IC50 49.0 nM
NCCCc1c[nH]c2ccc(F)cc12 CHEMBL1630733 IC50 50.0 nM
Fc1ccc2[nH]c([C@@H]3CCN(CC4NC=CN4)C3)nc2c1 CHEMBL4064328 IC50 50.0 nM
Nc1cc(Cc2ccn(Cc3ccc4ccccc4c3)n2)c2nn[nH]c2n1 CHEMBL4853722 IC50 52.0 nM
Nc1cc(Cc2ccn(-c3ccc(F)cc3)n2)c2nn[nH]c2n1 CHEMBL4869433 IC50 53.0 nM
Oc1ccccc1CNCCCc1c[nH]c2ccc(F)cc12 CHEMBL3933129 IC50 54.0 nM
Nc1cc(Cc2ccn(-c3ccccn3)n2)c2nn[nH]c2n1 CHEMBL4855030 IC50 54.0 nM
Nc1cc(Cc2ccn(-c3ccccc3)n2)c2nn[nH]c2n1 CHEMBL4859908 IC50 55.0 nM
Nc1cc(Cc2ccn(Cc3cccc(-c4ccccc4)c3)n2)c2nn[nH]c2n1 CHEMBL4863015 IC50 55.0 nM
Nc1cc(Cc2ccc3ccccc3c2)c2nn[nH]c2n1 CHEMBL4754467 IC50 57.0 nM
Nc1cc(Cc2ccn(Cc3ccc4c(c3)CCNC4)n2)c2nn[nH]c2n1 CHEMBL4855956 IC50 58.0 nM
N#CCCCc1c[nH]c2ccc(F)cc12 CHEMBL2347179 IC50 63.0 nM
NC(=O)CCc1c[nH]c2c(F)cccc12 CHEMBL2347182 IC50 64.0 nM
N[C@@H]1CC[C@@H](n2cc(-c3ccc4cc[nH]c4c3)c(C(F)(F)F)n2)C1 CHEMBL4637559 IC50 70.0 nM
Nc1cc([C@H](CCNCc2ccccc2)c2ccccc2)c2nn[nH]c2n1 CHEMBL4800005 IC50 72.0 nM
Nc1cc([C@H](CCN[C@H]2CCc3ccccc32)c2ccccc2)c2nn[nH]c2n1 CHEMBL4760380 IC50 72.0 nM
Nc1cc(Cc2cccc(-c3ccccc3)c2)c2nn[nH]c2n1 CHEMBL4742088 IC50 77.0 nM
Nc1nc(OCc2ccccc2F)c2nn[nH]c2n1 CHEMBL4293030 IC50 78.0 nM
Cn1cc(-c2cccc(COc3cc(N)nc4[nH]nnc34)c2)cn1 CHEMBL4590444 IC50 78.0 nM
CN(C)c1ccc(/C=N/Nc2nncc3ccccc23)cc1 CHEMBL3194273 IC50 80.0 nM
Nc1nc(OCc2ccccc2)c2[nH]nnc2n1 CHEMBL333928 IC50 84.0 nM
Oc1ccccc1CNCCc1c[nH]c2ccc(F)cc12 CHEMBL3929246 IC50 85.0 nM
c1c2c(cc3c4n(nc13)CCS4)OCO2 CHEMBL3343353 IC50 85.0 nM
Nc1cc(Cc2ccn(-c3cccc(-c4ccccc4)c3)n2)c2nn[nH]c2n1 CHEMBL4855931 IC50 85.0 nM
CN(C)CCc1c[nH]c2ccc(F)cc12 CHEMBL1630729 IC50 90.0 nM
c1ccc2c3n(nc2c1)CCS3 CHEMBL3343352 IC50 94.0 nM
Nc1cc([C@H](CCNCc2ccccc2C(F)(F)F)c2ccccc2)c2nn[nH]c2n1 CHEMBL4747086 IC50 94.0 nM
Cc1nc(N=C(N)N)nc2cc(Cl)ccc12 CHEMBL4098436 IC50 96.0 nM
O=C(Nn1c(=S)[nH]c2ccc(F)cc2c1=O)c1cccc(F)c1 CHEMBL3740646 IC50 100.0 nM
O=C(Nn1c(=S)[nH]c2ccc(F)cc2c1=O)c1ccc([N+](=O)[O-])cc1 CHEMBL3740322 IC50 100.0 nM
O=C(Nn1c(=S)[nH]c2ccc(F)cc2c1=O)c1ccc(C(F)(F)F)cc1 CHEMBL3739661 IC50 100.0 nM
O=c1c2cc(F)ccc2[nH]c(=S)n1Nc1ncc(C(F)(F)F)cc1Cl CHEMBL3740127 IC50 100.0 nM
Nc1cc(Cc2ccn(Cc3cccc(C4CCNCC4)c3)n2)c2nn[nH]c2n1 CHEMBL4859470 IC50 100.0 nM
Cc1nc(N=C(N)N)nc2cc(Br)ccc12 CHEMBL4069712 IC50 106.0 nM
OC/C=N/Nc1nncc2ccccc12 CHEMBL3883810 IC50 110.0 nM
N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 CHEMBL278555 IC50 110.0 nM
Nc1nc(Cc2ccccc2)c2nn[nH]c2n1 CHEMBL4762281 IC50 110.0 nM
Nc1cc(OCc2cc(-c3ccccc3)no2)c2nn[nH]c2n1 CHEMBL4528973 IC50 120.0 nM
CN(C)Cc1ccc(-n2cc(-c3ccc4cc[nH]c4c3)c3c(Cl)ccnc32)cc1 CHEMBL4645343 IC50 120.0 nM
Nc1cc(Cc2ccn(Cc3ccccc3)n2)c2nn[nH]c2n1 CHEMBL4846080 IC50 120.0 nM
Nc1cc([C@H](CCCc2ccccc2)c2ccccc2)c2nn[nH]c2n1 CHEMBL4763067 IC50 124.0 nM
CC(C)NCC(=O)c1nc2cc(F)ccc2[nH]1 CHEMBL4098162 IC50 130.0 nM
c1c2c(cc3c4n(nc13)CCCS4)OCO2 CHEMBL3343355 IC50 140.0 nM
Nc1nc(OCc2ccc(C(F)(F)F)cc2)c2nn[nH]c2n1 CHEMBL4294867 IC50 140.0 nM
Nc1cc(Cc2ccn(Cc3ccc4cnccc4c3)n2)c2nn[nH]c2n1 CHEMBL4871587 IC50 140.0 nM
CC(=O)NCc1cc(Cl)ccc1Cn1c(=S)[nH]c(=O)c2[nH]ccc21 CHEMBL5175091 IC50 140.3 nM
Nc1cc([C@H](Cc2ccccc2)c2ccccc2)c2nn[nH]c2n1 CHEMBL4761170 IC50 141.0 nM
Cc1nc(N=C(N)N)nc2ccc(F)cc12 CHEMBL4090447 IC50 145.0 nM
COc1ccc(/C=N/Nc2nncc3ccccc23)cc1O CHEMBL3884025 IC50 150.0 nM
COc1ccc(-c2cc(=O)[nH]c(=S)n2CCO)c(OC)c1 CHEMBL3633251 pKi 151.36 nM
Nc1cc([C@H](CCOCc2ccccc2)c2ccccc2)c2nn[nH]c2n1 CHEMBL4792720 IC50 159.0 nM
CCN(CC)CCc1c[nH]c2ccc(F)cc12 CHEMBL1630730 IC50 160.0 nM
Nc1cc(OCc2cccc(-c3ccccc3F)c2)c2nn[nH]c2n1 CHEMBL4544345 IC50 160.0 nM
CCCNCCCc1c[nH]c2ccc(F)cc12 CHEMBL1630736 IC50 170.0 nM
NC[C@H]1C[C@H](n2cc(-c3ccc4cc[nH]c4c3)c(C(F)(F)F)n2)C1 CHEMBL4632667 IC50 170.0 nM
COc1ccc(-c2cc(=O)[nH]c(=S)n2CCN)c(OC)c1 CHEMBL3633250 pKi 173.78 nM
Nc1nc(OCc2ccccc2Cl)c2nn[nH]c2n1 CHEMBL4285201 IC50 180.0 nM
CCNC(=O)CCCc1c[nH]c2ccc(F)cc12 CHEMBL2347029 IC50 182.0 nM
COc1ccc(Cl)cc1-c1cc(=O)[nH]c(=S)n1CC(N)=O CHEMBL3633460 IC50 187.0 nM
CCNCCCc1c[nH]c2ccc(F)cc12 CHEMBL1630735 IC50 190.0 nM
CCN(CC)Cc1c[nH]c2ccc(F)cc12 CHEMBL1630723 IC50 200.0 nM
NCCc1c[nH]c2ccc(F)cc12 CHEMBL275628 IC50 200.0 nM
CNCCc1c[nH]c2ccc(F)cc12 CHEMBL1630725 IC50 200.0 nM
CN1CCN(CCc2c[nH]c3ccc(F)cc23)CC1 CHEMBL1630732 IC50 200.0 nM
Cc1ccc(S(=O)(=O)Nn2c(=S)[nH]c3ccc(F)cc3c2=O)cc1 CHEMBL3741401 IC50 200.0 nM
Nc1nc(OCc2cccc(Cl)c2)c2nn[nH]c2n1 CHEMBL4288059 IC50 200.0 nM
Nc1nc(OCc2cccc(OC(F)F)c2)c2nn[nH]c2n1 CHEMBL4291458 IC50 200.0 nM
Fc1ccc2[nH]cc(CCCN3CCCC3)c2c1 CHEMBL1630739 IC50 210.0 nM
c1ccc2c3n(nc2c1)CCCS3 CHEMBL3343354 IC50 213.0 nM
Nc1ncnc2c1c(-c1ccc3cc[nH]c3c1)cn2-c1ccc(OCCNCCO)cc1 CHEMBL4637728 IC50 220.0 nM
NNC(=O)c1ccc(N)cc1 CHEMBL2170241 IC50 220.0 nM
CCCCNCCc1c[nH]c2ccc(F)cc12 CHEMBL1630728 IC50 250.0 nM
Nc1cc(OCc2nn(-c3ccccc3)nc2CO)c2nn[nH]c2n1 CHEMBL4524861 IC50 250.0 nM
FC(F)(F)c1nn(-c2ccc(Cc3nc[nH]n3)cc2)cc1-c1ccc2cc[nH]c2c1 CHEMBL4633000 IC50 250.0 nM
NCCCCCCc1c[nH]c2ccc(F)cc12 CHEMBL1630743 IC50 260.0 nM
Oc1ccccc1CCCNCc1ccccc1F CHEMBL3960919 IC50 270.0 nM
Nc1cc(Cc2ccccc2Cl)c2nn[nH]c2n1 CHEMBL4788921 IC50 286.0 nM
Nc1cc(OCc2ncc(-c3ccccc3)o2)c2nn[nH]c2n1 CHEMBL4465879 IC50 290.0 nM
CCNCCc1c[nH]c2ccc(F)cc12 CHEMBL1630726 IC50 300.0 nM
O=C(Nn1c(=S)[nH]c2ccc(F)cc2c1=O)c1ccccc1 CHEMBL3740039 IC50 300.0 nM
O=C(Nn1c(=S)[nH]c2cc3c(cc2c1=O)OCCO3)c1ccc(C(F)(F)F)cc1 CHEMBL3740920 IC50 300.0 nM
O=c1c2cc(F)ccc2[nH]c(=S)n1Nc1ccc(F)cc1 CHEMBL3741073 IC50 300.0 nM
Nn1c(=S)[nH]c2ccc(F)cc2c1=O CHEMBL3739975 IC50 300.0 nM
COc1cc(N[C@H](C)CCCN)c2ncccc2c1 CHEMBL251689 IC50 300.0 nM
CN1CCN(CCCc2c[nH]c3ccc(F)cc23)CC1 CHEMBL1630740 IC50 310.0 nM
Nc1ccc(Oc2cc(Cl)c(Cl)cc2Cl)cn1 CHEMBL4282403 IC50 320.0 nM
NCCCCn1cc(-c2ccc3cc[nH]c3c2)c(C(F)(F)F)n1 CHEMBL4649237 IC50 330.0 nM
COc1cc(/C=N/Nc2nncc3ccccc23)ccc1O CHEMBL3545483 IC50 340.0 nM
COc1ccc(OC)c(-c2cc(=O)[nH]c(=S)n2CC(N)=O)c1 CHEMBL3633459 pKi 346.74 nM
CCN(CC)CCCc1c[nH]c2ccc(F)cc12 CHEMBL1630738 IC50 350.0 nM
Oc1ccccc1CCCNCc1ccccc1O CHEMBL3920217 IC50 350.0 nM
CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC CHEMBL86 IC50 350.0 nM
c1ccc2c3n(nc2c1)CCCO3 CHEMBL1885837 IC50 359.0 nM
Oc1ccccc1CCCNCc1ccccc1 CHEMBL3892909 IC50 360.0 nM
Oc1ccccc1CCCNCc1cccc(F)c1 CHEMBL3899797 IC50 370.0 nM
Oc1ccccc1CNCCCc1ccccc1F CHEMBL3910108 IC50 370.0 nM
COc1ccc(-c2cc(=O)[nH]c(=S)n2CC(N)=O)c(OC)c1 CHEMBL3633248 pKi 371.54 nM
NNC(=O)Cn1c(=S)[nH]c2ccccc21 CHEMBL5434237 IC50 390.0 nM
O=c1c2ccccc2[nH]c(=S)n1CCN1CCCCC1 CHEMBL1409565 IC50 400.0 nM
COc1cc2[nH]c(=S)n(NC(=O)c3ccc(C(F)(F)F)cc3)c(=O)c2cc1OC CHEMBL3740924 IC50 400.0 nM
O=C(Nn1c(=S)[nH]c2ccc(F)cc2c1=O)c1ccc(CN2CCCCC2)cc1 CHEMBL3740464 IC50 400.0 nM
Nc1cc(OCc2cn(-c3ccccc3)nn2)c2nn[nH]c2n1 CHEMBL4561755 IC50 400.0 nM
c1c2c(cc3c4n(nc13)CCCO4)OCO2 CHEMBL3343351 IC50 403.0 nM
Nc1ccc(S(=O)(=O)c2ccc(N)cc2)cc1 CHEMBL1043 IC50 420.0 nM
N[C@@H](c1ccc(-n2cc(-c3ccc4cc[nH]c4c3)c(C(F)(F)F)n2)cc1)C(F)(F)F CHEMBL4641477 IC50 420.0 nM
COc1ccc(/C=N/NC(=O)c2ccncc2)cc1O CHEMBL3885085 IC50 430.0 nM
CCCNCCc1c[nH]c2ccc(F)cc12 CHEMBL1630727 IC50 460.0 nM
Cn1c(=O)[nH]c(=O)c2c1nc(NCCN)n2CCCOc1ccccc1 CHEMBL2170247 IC50 460.0 nM
COc1cc(/C=N/NC(=O)c2ccncc2)ccc1O CHEMBL2105120 IC50 460.0 nM
Cc1ccccc1COc1nc(N)nc2[nH]nnc12 CHEMBL4284666 IC50 470.0 nM
Oc1ccccc1CCCNCc1ccc(F)cc1 CHEMBL3980103 IC50 490.0 nM
COc1cccc(COc2nc(N)nc3[nH]nnc23)c1 CHEMBL4277419 IC50 490.0 nM
Oc1ccccc1CN1CCCN(Cc2ccccc2O)C1 CHEMBL1370773 IC50 500.0 nM
O=c1c2cc(F)ccc2[nH]c(=S)n1NC(=S)Nc1cccc(F)c1 CHEMBL3740416 IC50 500.0 nM
COc1ccc(-c2cc(=O)[nH]c(=S)n2CCOC(C)C)c(OC)c1 CHEMBL3633457 pKi 501.19 nM
Cc1ccc(COc2nc(N)nc3[nH]nnc23)cc1 CHEMBL4284241 IC50 510.0 nM
COc1ccc(-c2cc(=O)[nH]c(=S)n2CC(=O)NCCN)c(OC)c1 CHEMBL3633249 IC50 600.0 nM
CN(C)CCCn1c(=S)[nH]c2ccc(F)cc2c1=O CHEMBL3740429 IC50 600.0 nM
Nc1cc([C@H](CCNCc2ccccn2)c2ccccc2)c2nn[nH]c2n1 CHEMBL4763260 IC50 616.0 nM
Cc1nc(N=C(N)N)nc2ccc(Cl)cc12 CHEMBL4089529 IC50 630.0 nM
Nc1nc(OCCc2ccccc2)c2nn[nH]c2n1 CHEMBL4279798 IC50 630.0 nM
CC(C)OCCn1c(=S)[nH]c(=O)c2[nH]ccc21 CHEMBL4297594 IC50 630.0 nM
Oc1ccccc1CCNCc1ccccc1O CHEMBL3919858 IC50 650.0 nM
CC(C)n1[nH]c2ccccc2c1=O CHEMBL3145355 IC50 660.0 nM
Oc1ccccc1CCNCc1cccc(F)c1 CHEMBL3890813 IC50 660.0 nM
Oc1ccccc1CNCCc1ccccc1F CHEMBL3980225 IC50 670.0 nM
Nc1cc(Cc2cccc(C(F)(F)F)c2)c2nn[nH]c2n1 CHEMBL4742000 IC50 683.0 nM
Oc1ccccc1CCNCc1ccccc1F CHEMBL3981926 IC50 700.0 nM
Oc1ccccc1CNCCc1ccccc1 CHEMBL3925807 IC50 700.0 nM
COc1c2ccccc2nn1C(C)C CHEMBL3343327 IC50 704.0 nM
COc1c2cc3c(cc2nn1C(C)C)OCO3 CHEMBL3343330 IC50 711.0 nM
CS(=O)(=O)c1ccccc1COc1cc(N)nc2[nH]nnc12 CHEMBL4528131 IC50 720.0 nM
CCOc1c2ccccc2nn1C(C)C CHEMBL3343328 IC50 722.0 nM
Cc1nc(N=C(N)N)nc2ccc(Br)cc12 CHEMBL4076541 IC50 756.0 nM
NCCc1c[nH]c2ccccc12 CHEMBL6640 IC50 770.0 nM
CCCCn1[nH]c2ccccc2c1=O CHEMBL3144791 IC50 792.0 nM
CN(C)CCCn1c(=S)[nH]c2ccc(Cl)cc2c1=O CHEMBL3740321 IC50 800.0 nM
COc1cc2[nH]c(=S)n(N)c(=O)c2cc1OC CHEMBL3740128 IC50 800.0 nM
CCCCn1nc2ccccc2c1OCC CHEMBL3343332 IC50 807.0 nM
CC(C)CN1C(=O)C2=NC=NC2=NC1=S CHEMBL2170242 IC50 870.0 nM
NCc1c[nH]c2ccc(F)cc12 CHEMBL1630722 IC50 900.0 nM
CC1COc2c3ccccc3nn21 CHEMBL2141595 IC50 900.0 nM
COc1cc2[nH]c(=S)n(NC(=O)c3cccc(F)c3)c(=O)c2cc1OC CHEMBL3739930 IC50 900.0 nM
NNc1nncc2ccccc12 CHEMBL276832 IC50 900.0 nM
Cc1nc(NC(=N)N)nc2ccccc12 CHEMBL602365 IC50 900.0 nM
CCCCn1nc2ccccc2c1OC CHEMBL3343331 IC50 910.0 nM
COc1cc(-c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)ccc1OCC(=O)O CHEMBL2170246 IC50 970.0 nM
Cc1cccc(Nc2ccccc2C(=O)O)c1C CHEMBL686 IC50 980.0 nM
CN1CCN(Cc2c[nH]c3ccc(F)cc23)CC1 CHEMBL1630724 IC50 1000.0 nM
CCC(=O)Nn1c(=S)[nH]c2ccc(F)cc2c1=O CHEMBL3742363 IC50 1000.0 nM
CC(C)(C)C(=O)Nn1c(=S)[nH]c2ccc(F)cc2c1=O CHEMBL3740124 IC50 1000.0 nM