NC1N=CNc2c(CN3CC(O)C(CSc4ccc(Cl)cc4)C3)c[nH]c21 CHEMBL365813 Ki 0.01 nM
CCSCC1CN(Cc2c[nH]c3c2NC=NC3N)CC1O CHEMBL191544 Ki 0.034 nM
CSC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O CHEMBL405346 Ki 0.078 nM
CSCC1CN(Cc2c[nH]c3c(N)ncnc23)CC1O CHEMBL188375 Ki 0.09 nM
CCCCSCC1CN(Cc2c[nH]c3c2NC=NC3N)CC1O CHEMBL365378 Ki 0.11 nM
CCCSCC1CN(Cc2c[nH]c3c2NC=NC3N)CC1O CHEMBL425188 Ki 0.12 nM
NC1N=CNc2c(CN3CC(O)C(CSc4ccc(F)cc4)C3)c[nH]c21 CHEMBL190216 Ki 0.16 nM
NC1N=CNc2c(CN3CC(O)C(CSc4ccncc4)C3)c[nH]c21 CHEMBL190139 Ki 0.16 nM
Nc1[nH]cnc2c(C3NC(CSc4ccc(Cl)cc4)C(O)C3O)cnc1-2 CHEMBL552894 Ki 0.166 nM
NC1N=CNc2c(CN3CC(O)C(CSc4ccccc4)C3)c[nH]c21 CHEMBL188034 Ki 0.17 nM
CCCSCC1NC(c2c[nH]c3c(N)ncnc23)C(O)C1O CHEMBL544806 Ki 0.214 nM
CC(C)SCC1CN(Cc2c[nH]c3c2NC=NC3N)CC1O CHEMBL191281 Ki 0.26 nM
CCSCC1NC(c2c[nH]c3c(N)ncnc23)C(O)C1O CHEMBL554965 Ki 0.266 nM
NC1N=CNc2c(CN3CC(O)C(CSc4cccc(Cl)c4)C3)c[nH]c21 CHEMBL191177 Ki 0.27 nM
NC1N=CNc2c(CN3CC(O)C(CSC4CCCCC4)C3)c[nH]c21 CHEMBL190867 Ki 0.37 nM
CCCC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O CHEMBL1243249 Ki 0.55 nM
Cc1cccc(SCC2NC(c3c[nH]c4c(N)ncnc34)C(O)C2O)c1 CHEMBL542449 Ki 0.628 nM
C#CCSC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O CHEMBL4445386 Kd 0.63 nM
Cc1ccc(SCC2NC(c3c[nH]c4c(N)ncnc34)C(O)C2O)cc1 CHEMBL544110 Ki 0.64 nM
Nc1[nH]cnc2c(CN3CC(O)C(CSCc4ccccc4)C3)cnc1-2 CHEMBL191436 Ki 0.7 nM
CC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O CHEMBL1241349 Ki 0.7 nM
C#CCCCSC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O CHEMBL4465346 Kd 0.94 nM
Nc1[nH]cnc2c(C3NC(CSc4ccccc4)C(O)C3O)cnc1-2 CHEMBL545042 Ki 1.0 nM
CSCC1NC(c2c[nH]c3c(N)ncnc23)C(O)C1O CHEMBL554322 Ki 1.0 nM
CSCC1NC(c2c[nH]c3c(N)ncnc23)C(O)C1O CHEMBL1161749 Ki 1.0 nM
CSC[C@H]1N[C@@H](c2c[nH]c3c(N)ncnc23)[C@H](O)[C@@H]1O CHEMBL1195586 Ki 1.0 nM
CSC[C@H]1N[C@@H](c2c[nH]c3c(N)ncnc23)[C@H](O)[C@@H]1O CHEMBL554896 IC50 1.2 nM
CCCCn1cc(CCCSC[C@H]2CN(Cc3c[nH]c4c(N)ncnc34)C[C@@H]2O)nn1 CHEMBL4450105 Kd 1.3 nM
Nc1ncnc2c(CN3C[C@H](CSCCCc4cn(Cc5ccccc5)nn4)[C@@H](O)C3)c[nH]c12 CHEMBL4439603 Kd 1.4 nM
CC(C)C[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O CHEMBL1243250 Ki 1.7 nM
Nc1[nH]cnc2c(C3NC(CSc4ccc(F)cc4)C(O)C3O)cnc1-2 CHEMBL545740 Ki 2.0 nM
CSCC1CN(Cc2c[nH]c3c(N)ncnc23)C1 CHEMBL405371 Ki 2.0 nM
Nc1ncnc2c(CN3C[C@H](C4CC4)[C@@H](O)C3)c[nH]c12 CHEMBL1241380 Ki 2.1 nM
C=CCn1cc(CCCSC[C@H]2CN(Cc3c[nH]c4c(N)ncnc34)C[C@@H]2O)nn1 CHEMBL4469234 Kd 2.4 nM
Nc1ncnc2c(CN3C[C@H](C4CCCC4)[C@@H](O)C3)c[nH]c12 CHEMBL1243279 Ki 2.6 nM
CCCC1CN(Cc2c[nH]c3c2NC=NC3N)CC1O CHEMBL189911 Ki 3.0 nM
C=CC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O CHEMBL1240542 Ki 3.0 nM
Cn1cc(CCCSC[C@H]2CN(Cc3c[nH]c4c(N)ncnc34)C[C@@H]2O)nn1 CHEMBL4469129 Kd 3.0 nM
Nc1[nH]cnc2c(C3NC(CSCCF)C(O)C3O)cnc1-2 CHEMBL542694 Ki 3.2 nM
C=C[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O CHEMBL1241381 Ki 3.2 nM
CSC[C@@H](CO)NCc1c[nH]c2c(N)ncnc12 CHEMBL2070308 Ki 4.4 nM
CSC[C@@H](O)[C@@H](CO)NCc1c[nH]c2c(N)ncnc12 CHEMBL2070311 Ki 5.2 nM
Nc1[nH]cnc2c(C3NC(CSc4cccc(Cl)c4)C(O)C3O)cnc1-2 CHEMBL553982 Ki 6.4 nM
COCC1CN(Cc2c[nH]c3c2NC=NC3N)CC1O CHEMBL189837 Ki 8.0 nM
Nc1ncnc2c(CN3C[C@H](c4ccccc4)[C@@H](O)C3)c[nH]c12 CHEMBL1243311 Ki 8.0 nM
CSCC(CO)CNCc1c[nH]c2c(N)ncnc12 CHEMBL2070310 Ki 10.0 nM
CSCC(CO)NCc1c[nH]c2c(N)ncnc12 CHEMBL2070307 Ki 12.0 nM
CSC[C@@H](CN(C)Cc1c[nH]c2c(N)ncnc12)[C@@H](O)CO CHEMBL2070405 Ki 12.0 nM
Nc1ncnc2c(CN3C[C@H](CSCc4cn(Cc5ccccc5)nn4)[C@@H](O)C3)c[nH]c12 CHEMBL4444249 Kd 13.0 nM
Nc1ncnc2c(CN3C[C@H](CSc4ncccn4)[C@@H](O)C3)c[nH]c12 CHEMBL4451807 Kd 13.0 nM
Nc1[nH]cnc2c(C3NC(CSCCO)C(O)C3O)cnc1-2 CHEMBL542697 Ki 14.0 nM
Nc1ncnc2c(CN3C[C@H](CC4CCCCC4)[C@@H](O)C3)c[nH]c12 CHEMBL1243280 Ki 14.0 nM
CCC(CC)C[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O CHEMBL1243278 Ki 18.0 nM
CSC[C@H]1CN(Cc2[nH]nc3c(N)ncnc23)C[C@@H]1O CHEMBL4472065 Kd 19.0 nM
Nc1[nH]cnc2c(C3NC(CSCc4ccccc4)C(O)C3O)cnc1-2 CHEMBL554642 Ki 26.0 nM
C#C[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O CHEMBL1241431 Ki 31.0 nM
CSC[C@H]1CN(Cc2c[nH]c3c(N)nccc23)C[C@@H]1O CHEMBL4586326 Kd 31.9 nM
CC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@H]1O CHEMBL1241432 Ki 34.0 nM
CSC[C@H](CO)NCc1c[nH]c2c(N)ncnc12 CHEMBL2070309 Ki 34.0 nM
CSC[C@@H](O)[C@H](CO)NCc1c[nH]c2c(N)ncnc12 CHEMBL2070401 Ki 34.0 nM
CSCC(CO)(CO)NCc1c[nH]c2c(N)ncnc12 CHEMBL2070402 Ki 34.0 nM
CSC[C@@H](CNCc1c[nH]c2c(N)ncnc12)[C@@H](O)CO CHEMBL2070404 Ki 34.0 nM
CCCCn1cc(CSC[C@H]2CN(Cc3c[nH]c4c(N)ncnc34)C[C@@H]2O)nn1 CHEMBL4555691 Kd 37.0 nM
NC1N=CNc2c(CN3CC(O)C(COCc4ccccc4)C3)c[nH]c21 CHEMBL189910 Ki 42.0 nM
CCCC1NC(c2c[nH]c3c(N)ncnc23)C(O)C1O CHEMBL542452 Ki 44.0 nM
Nc1ncnc2c(CN3CC(O)C(CSCc4ccccc4)C3)n[nH]c12 CHEMBL190954 Ki 55.0 nM
Nc1ncnc2c(CN3C[C@H](O)[C@@H](n4ccnn4)C3)c[nH]c12 CHEMBL1243312 Ki 59.0 nM
Cn1cc(CSC[C@H]2CN(Cc3c[nH]c4c(N)ncnc34)C[C@@H]2O)nn1 CHEMBL4439224 Kd 66.0 nM
C=CCn1cc(CSC[C@H]2CN(Cc3c[nH]c4c(N)ncnc34)C[C@@H]2O)nn1 CHEMBL4555970 Kd 70.0 nM
Nc1ncnc2c(CN3C[C@H](CCCSCc4ccccc4)[C@@H](O)C3)c[nH]c12 CHEMBL1243341 Ki 71.0 nM
CSC[C@H](O)[C@H](CO)NCc1c[nH]c2c(N)ncnc12 CHEMBL2070312 Ki 87.0 nM
CSC[C@H](O)[C@@H](CO)NCc1c[nH]c2c(N)ncnc12 CHEMBL2070400 Ki 87.0 nM
Nc1[nH]cnc2c(C3NC(CSc4cccc5ccccc45)C(O)C3O)cnc1-2 CHEMBL553375 Ki 90.0 nM
CSC[C@H](O)[C@@H](CO)CN(C)Cc1c[nH]c2c(N)ncnc12 CHEMBL2070406 Ki 105.0 nM
CSC[C@H](CO)N[C@H](CO)c1c[nH]c2c(N)ncnc12 CHEMBL2070408 Ki 130.0 nM
COCC1NC(c2c[nH]c3c(N)ncnc23)C(O)C1O CHEMBL544574 Ki 134.0 nM
CSCC1(CO)CN(Cc2c[nH]c3c(N)ncnc23)C1 CHEMBL407216 Ki 140.0 nM
CSC[C@H](O)[C@@H](O)CN(C)Cc1c[nH]c2c(N)ncnc12 CHEMBL2070407 Ki 368.0 nM
CSC[C@@H](O)CNCc1c[nH]c2c(N)ncnc12 CHEMBL2070403 Ki 602.0 nM
CC1NC(c2c[nH]c3c(N)ncnc23)C(O)C1O CHEMBL545273 Ki 720.0 nM
CSC[C@@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@H]1O CHEMBL3604360 Ki 750.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSc2ccncc2)[C@@H](O)[C@H]1O CHEMBL196596 Km 880.0 nM