CC(=O)NCCC1=C(c2ccoc2)Cc2ccc3c(c21)CCO3 CHEMBL1774523 Ki 0.0065 nM
CCCC(=O)NCC1CCc2cccc3ccc(OC)c1c23 CHEMBL131252 Ki 0.008 nM
CC(=O)NCCC1=C(c2ccccc2)Cc2ccc3c(c21)CCO3 CHEMBL1774522 Ki 0.0082 nM
CC(=O)NCCC1=C(Br)Cc2ccc3c(c21)CCO3 CHEMBL1774521 Ki 0.0087 nM
COc1ccc2oc(-c3ccccc3)c(CCNC(C)=O)c2c1 CHEMBL287560 Ki 0.01 nM
C=CCC(=O)NCCc1c(-c2ccccc2)oc2ccc(OC)cc12 CHEMBL330137 Ki 0.01 nM
COc1ccc2cccc3c2c1C(CNC(C)=O)CC3 CHEMBL132802 Ki 0.01 nM
CCC(=O)NCC1CCc2c(OC)ccc3ccc(OC)c1c23 CHEMBL336054 Ki 0.012 nM
COc1c[nH]c2nc(-c3ccccc3)c(CCNC(C)=O)c-2c1 CHEMBL139855 pIC50 0.01259 nM
COc1ccc2[nH]c(I)c(CCNC(C)=O)c2c1 CHEMBL289233 Ki 0.013 nM
CCC(=O)NCCC1=C(C(C)C)Cc2ccc3c(c21)CCO3 CHEMBL1774514 Ki 0.013 nM
CCC(=O)NCC[C@@H]1CCc2ccc3c(c21)CCO3 CHEMBL1218 Ki 0.0138 nM
COc1ccc2ccc(OC)c3c2c1CCC3CNC(C)=O CHEMBL336509 Ki 0.015 nM
CC(=O)NCC[C@@H]1CCc2ccc3nc(C)oc3c21 CHEMBL3648356 EC50 0.015 nM
COc1ccc2oc(Cc3ccccc3)c(CCNC(C)=O)c2c1 CHEMBL329263 pIC50 0.01585 nM
CCCC(=O)NCC1CCc2c(OC)ccc3ccc(OC)c1c23 CHEMBL340832 Ki 0.016 nM
C=CC(=O)NCCc1c(-c2ccccc2)oc2ccc(OC)cc12 CHEMBL314512 Ki 0.02 nM
CCc1nn2ccc3c(c2c1CCNC(C)=O)CCO3 CHEMBL1802025 EC50 0.021 nM
COc1ccc2[nH]c(-c3ccccc3)c(CCNC(C)=O)c2c1 CHEMBL15060 pKi 0.02188 nM
CC(=O)NCCC1CCc2ccc3nc(CCCCc4ccccc4)oc3c21 CHEMBL3648361 IC50 0.022 nM
COc1ccc2[nH]cc(CCNC(C)=O)c2c1 CHEMBL45 EC50 0.022 nM
CC(=O)NCCC1=C(C(C)C)Cc2ccc3c(c21)CCO3 CHEMBL1774513 Ki 0.024 nM
COc1ccc2ccc(OC)c3c2c1CCC3CNC(=O)C1CC1 CHEMBL133416 Ki 0.026 nM
CCC(=O)NCCc1c(C2CC2)nn2ccc3c(c12)CCO3 CHEMBL1802028 Ki 0.026 nM
CCC(=O)NCCC1CCc2ccc3nc(C)sc3c21 CHEMBL4868554 Ki 0.027 nM
CC(=O)NCCc1cccc2ccc(OCCCCCCCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12 CHEMBL14417 Ki 0.03 nM
CCCC(=O)NCC1Cc2cccc3ccc(OC)c1c23 CHEMBL130214 Ki 0.03 nM
COc1ccc2ccc(OC)c(/C=C/NC(C)=O)c2c1 CHEMBL2314259 Ki 0.03 nM
CCC(=O)NCC1CCc2c(OC)cccc2N1C CHEMBL3612603 Ki 0.03 nM
CCC(=O)NCC[C@@H]1CCc2ccc3nc(C)oc3c21 CHEMBL3648359 IC50 0.03 nM
CC(C)C1=C(CCNC(=O)C(F)(F)F)c2c(ccc3c2CCO3)C1 CHEMBL1774516 Ki 0.032 nM
CCOc1nc2cc(Cl)c(OC)cc2n1CCNC(C)=O CHEMBL4852096 EC50 0.035 nM
CCOc1nc2ccc(OC)cc2n1CCCNC(C)=O CHEMBL4848885 EC50 0.036 nM
CCOc1nc2ccc3c(c2n1CCNC(C)=O)CCO3 CHEMBL4852440 EC50 0.037 nM
CC(=O)NCCC1CCc2ccc3nc(C)sc3c21 CHEMBL3648362 Ki 0.037 nM
CC(=O)NCC[C@@H]1CCc2ccc3nc(C)sc3c21 CHEMBL3648363 IC50 0.038 nM
CCC(=O)NCCc1c(CC)nn2ccc3c(c12)CCO3 CHEMBL1802026 Ki 0.039 nM
CNC(=O)NCCc1c(-c2ccccc2)oc2ccc(OC)cc12 CHEMBL94838 Ki 0.04 nM
COc1ccc2[nH]c(-c3ccccc3)c(CCNC(C)=O)c2n1 CHEMBL1823015 Ki 0.04 nM
COc1ccc2cccc(/C=C/NC(C)=O)c2c1 CHEMBL2314255 Ki 0.04 nM
COc1ccc2oc(-c3ccccc3)c(CCNC(C)=O)c2n1 CHEMBL3765540 Ki 0.04 nM
CCOc1nc2ccc(OC)cc2n1CCNC(C)=O CHEMBL4859677 EC50 0.04 nM
COc1ccc2nc(OC)n(CCNC(C)=O)c2c1 CHEMBL4854625 EC50 0.042 nM
COc1nc2ccc3c(c2n1CCNC(C)=O)CCO3 CHEMBL4873903 EC50 0.042 nM
CC(=O)NCCc1c(C2CC2)nn2ccc3c(c12)CCO3 CHEMBL1802027 Ki 0.044 nM
CC(=O)NCCC1=CCc2ccc3c(c21)CCO3 CHEMBL1774512 Ki 0.045 nM
CC(=O)NCCc1cccc2ccc(OCCCCCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12 CHEMBL14136 Ki 0.05 nM
CC(=O)NCCc1cccc2ccc(OCCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12 CHEMBL273787 Ki 0.05 nM
CCCC(=O)NC[C@@H]1C[C@H]1c1cccc2c1OC(CCCCc1ccccc1)N2 CHEMBL19026 Ki 0.05 nM
CCCC(=O)NC[C@@H]1C[C@H]1c1cccc2nc(CC)oc12 CHEMBL2112722 Ki 0.05 nM
CC(=O)NC[C@@H]1C[C@H]1c1cccc2nc(CCCCc3ccccc3)oc12 CHEMBL2112700 Ki 0.05 nM
CCC(=O)NC[C@@H]1C[C@H]1c1cccc2nc(CCCCc3ccccc3)oc12 CHEMBL2112690 Ki 0.05 nM
CCC(=O)NC[C@@H]1C[C@H]1c1cccc2nc(CC)oc12 CHEMBL2112727 Ki 0.05 nM
CCc1nc2cccc([C@@H]3C[C@H]3CNC(=O)C3CC3)c2o1 CHEMBL2112724 Ki 0.05 nM
O=C(NC[C@@H]1C[C@H]1c1cccc2nc(CCCCc3ccccc3)oc12)C1CC1 CHEMBL2112734 Ki 0.05 nM
COc1cccc(N(C)c2ccc(NC(C)=O)cc2)c1 CHEMBL8168 Ki 0.05 nM
COc1ccc2ccc3c(c2n1)C(CNC(C)=O)CC3 CHEMBL4281712 EC50 0.05 nM
COc1ccc2cccc(CCNC(=O)C(F)F)c2c1 CHEMBL1946221 pKi 0.0537 nM
CCCC(=O)NCCC1CCc2c(OC)ccc3ccc(OC)c1c23 CHEMBL129890 Ki 0.057 nM
COc1cccc(C2=C(CCNC(C)=O)c3c(ccc4c3CCO4)C2)c1 CHEMBL1774526 Ki 0.057 nM
COc1ccc2cccc(CCNC(C)=O)c2c1 CHEMBL10878 Ki 0.06 nM
COc1ccc2ccc(OC)c([C@@H]3C[C@H]3NC(C)=O)c2c1 CHEMBL2314253 Ki 0.06 nM
COc1cc2c(cc1Cl)nc(OC)n2CCNC(C)=O CHEMBL4859295 EC50 0.063 nM
CC(=O)NCCC1CCc2ccc3nc(C)oc3c21 CHEMBL3648355 Ki 0.067 nM
CCC(=O)NCCC1CCc2ccc3nc(C)oc3c21 CHEMBL3648358 Ki 0.067 nM
CC(=O)NCCC1=CCc2ccc3nc(C)oc3c21 CHEMBL3648350 IC50 0.068 nM
CC(=O)NCCC1=C(c2cccnc2)Cc2ccc3c(c21)CCO3 CHEMBL1774524 Ki 0.069 nM
CCC(=O)NCCC1CCc2c(OC)ccc3ccc(OC)c1c23 CHEMBL337024 Ki 0.07 nM
COC(=O)Cc1cccc2ccc(OCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12 CHEMBL1095196 Ki 0.07 nM
CC(=O)NC/C=C1\CCc2ccc3nc(CCCCc4ccccc4)oc3c21 CHEMBL4114715 IC50 0.079 nM
COc1cc2c([C@@H](C)CNC(C)=O)c[nH]c2cc1Cl CHEMBL4079759 pKi 0.07943 nM
CC(=O)NCCc1cccc2ccc(OCCCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12 CHEMBL13985 Ki 0.08 nM
COc1ccc2c(c1)c(CCNC(C)=O)c(I)n2C CHEMBL300056 Ki 0.08 nM
CC(=O)NCCc1c(-c2ccccc2)nn2ccc3c(c12)CCO3 CHEMBL1802022 Ki 0.082 nM
CCC(=O)NCCc1c(C)nn2ccc3c(c12)CCO3 CHEMBL1802024 Ki 0.083 nM
CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc(-c4ccc(CO)cc4)cc3)cc12 CHEMBL1094212 Ki 0.09 nM
Cc1nc2ccc3c(c2o1)C(CCNC(=O)C(F)(F)F)CC3 CHEMBL3648369 IC50 0.095 nM
CCC(=O)NCCc1c(OC)ccc2ccc(OC)cc12 CHEMBL291857 Ki 0.099 nM
COc1ccc2cccc3c2c1C(CCNC(C)=O)CC3 CHEMBL132340 Ki 0.1 nM
CCC(=O)NCC1Cc2cccc3ccc(OC)c1c23 CHEMBL130542 Ki 0.1 nM
COc1ccc2ccccc2c1/C=C/NC(C)=O CHEMBL2314257 Ki 0.1 nM
COc1ccc2ccc3c(c2c1)C(C)(CNC(C)=O)CC3 CHEMBL4278248 Ki 0.1 nM
CCCC(=O)NCC1CCc2c(OC)ccc3cccc1c23 CHEMBL131424 Ki 0.11 nM
CC(C)C1=C(CCNC(=O)C2CC2)c2c(ccc3c2CCO3)C1 CHEMBL1774515 Ki 0.11 nM
COc1ccc2cccc3c2c1C(CNC(C)=O)C3 CHEMBL130490 Ki 0.12 nM
CC(C)C(=O)NC[C@@H]1C[C@H]1c1cccc2c1OC(CCCCc1ccccc1)N2 CHEMBL18845 Ki 0.13 nM
CCCC(=O)N[C@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL136531 Ki 0.14 nM
CCCC(=O)NCCn1c(OCC)nc2ccc(OC)cc21 CHEMBL4874954 EC50 0.14 nM
COc1ccc2occ(CCNC(C)=O)c2c1 CHEMBL323332 Ki 0.15 nM
CC(=O)NCCc1c[nH]c2ccc(OCCc3ccccc3)cc12 CHEMBL4467954 Ki 0.15 nM
CC(=O)NCCc1cccc2ccc3c(c12)C=CCO3 CHEMBL11356 pIC50 0.1585 nM
CC(=O)NCCc1c(C)nn2ccc3c(c12)CCO3 CHEMBL1802023 Ki 0.16 nM
COc1ccc2[nH]c(-c3cccnc3)c(CCNC(C)=O)c2c1 CHEMBL5417297 pKi 0.1698 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4128926 IC50 0.17 nM
CCC(=O)NCCC1CCc2ccn3nc(C)cc3c21 CHEMBL4874630 Ki 0.17 nM
CCC(=O)N[C@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL343825 Ki 0.18 nM
CCCC1Nc2cccc([C@@H]3C[C@H]3CNC(=O)C3CC3)c2O1 CHEMBL279343 Ki 0.18 nM
CCOC(=O)c1[nH]c2ccc(OC)c3c2c1[C@@H](CNC(C)=O)CC3 CHEMBL3260982 Ki 0.18 nM
CCC(=O)NCC1CCc2c(OC)ccc3cccc1c23 CHEMBL129889 Ki 0.19 nM
CC(=O)NC/C=C1\CCc2ccc3nc(C)sc3c21 CHEMBL4115681 IC50 0.19 nM
CCC1Nc2cccc([C@@H]3C[C@H]3CNC(=O)C(C)C)c2O1 CHEMBL431103 Ki 0.2 nM
COc1ccc2ccc(OC)c3c2c1CCC3CCNC(C)=O CHEMBL130898 Ki 0.2 nM
COc1ccc2[nH]cc(CCNC(C)=O)c2n1 CHEMBL1760944 Ki 0.2 nM
CNC(=O)N/C=C/c1c(OC)ccc2ccc(OC)cc12 CHEMBL2314260 Ki 0.2 nM
COc1ccc2oc(I)c(CCNC(C)=O)c2n1 CHEMBL3765401 Ki 0.2 nM
COc1ccc2oc(-c3ccc(F)cc3)c(CCNC(C)=O)c2n1 CHEMBL3763503 Ki 0.2 nM
CNC(=O)NCC1CCc2ccc3ccc(OC)nc3c21 CHEMBL4283539 EC50 0.2 nM
CC(=O)NCCC1CCc2ccn3nc(C)cc3c21 CHEMBL4874010 Ki 0.2 nM
CCCC1Nc2cccc([C@@H]3C[C@H]3CNC(=O)CC)c2O1 CHEMBL276921 Ki 0.22 nM
CCC(=O)NCCC1Cc2cccc3ccc(OC)c1c23 CHEMBL336858 Ki 0.22 nM
CCc1nc2ccc3c(c2o1)C(CCNC(C)=O)CC3 CHEMBL3648365 Ki 0.22 nM
COc1ccc2nc(OC)n(CCCNC(C)=O)c2c1 CHEMBL4854836 EC50 0.233 nM
COc1ccc2nc(SC)n(CCNC(C)=O)c2c1 CHEMBL4867553 EC50 0.24 nM
CCC(=O)NC/C=C1\CCc2ccc3nc(C)oc3c21 CHEMBL4114700 IC50 0.25 nM
Cc1nc2ccc3c(c2o1)C(CCNC(=O)C1CC1)CC3 CHEMBL3648368 IC50 0.25 nM
CC(=O)NCCc1cccc2ccc3c(c12)CCCO3 CHEMBL274358 pIC50 0.2512 nM
COc1ccc2c(c1)c(CCNC(C)=O)cn2Cc1cc(OC)c(OC)cc1[N+](=O)[O-] CHEMBL5174929 pEC50 0.257 nM
CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4c(c3)C(CCNC(C)=O)CCC4)cc12 CHEMBL1095831 Ki 0.26 nM
COc1cc2c(CCNC(C)=O)c(I)[nH]c2cc1[N+](=O)[O-] CHEMBL52755 Ki 0.3 nM
COc1ccc2cccc([C@@H]3C[C@H]3NC(C)=O)c2c1 CHEMBL2314251 Ki 0.3 nM
COc1ccc2cccc(CCNC(C)=O)c2n1 CHEMBL4102177 Ki 0.3 nM
COc1ccc2ccc3c(c2c1)C(CNC(C)=O)CC3 CHEMBL4293386 Ki 0.3 nM
COc1ccc2ccc3c(c2c1)C(CNC(N)=O)CC3 CHEMBL4278575 Ki 0.3 nM
CCC(=O)NCCC1CCc2ccc3nn(C)cc3c21 CHEMBL4869029 Ki 0.3 nM
CCC(=O)NCCc1c(C(F)(F)F)nn2ccc3c(c12)CCO3 CHEMBL1802030 Ki 0.31 nM
COc1ccc2cc(C(=O)c3ccccc3)cc(CCNC(C)=O)c2c1 CHEMBL337764 pIC50 0.3162 nM
CC(=O)NC/C=C1\CCc2ccc3nc(C)oc3c21 CHEMBL4114658 IC50 0.33 nM
CCC1Nc2cccc([C@@H]3C[C@H]3CNC(C)=O)c2O1 CHEMBL18960 Ki 0.35 nM
CC(=O)NCCC1CCc2ccc3nn(C)cc3c21 CHEMBL4872592 Ki 0.35 nM
CCCC(=O)NCCC1Cc2cccc3ccc(OC)c1c23 CHEMBL434226 Ki 0.37 nM
COC(=O)C(C)c1ccc2cc(OCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)ccc2c1 CHEMBL1095197 Ki 0.37 nM
CCOc1ccc2ccc(OC)cc2c1CCNC(=O)CC CHEMBL80736 Ki 0.39 nM
CC(=O)NCCC1CCc2ccc3nc(C4CC4)oc3c21 CHEMBL3648366 Ki 0.39 nM
CNC(=O)NCC1CCc2ccc3ccc(OC)cc3c21 CHEMBL4279639 Ki 0.4 nM
COc1ccc2cccc3c2c1C(CCNC(C)=O)C3 CHEMBL130203 Ki 0.41 nM
CCN(CC)c1ccc2c(COC(=O)n3cc(CCNC(C)=O)c4cc(OC)ccc43)cc(=O)oc2c1 CHEMBL5209359 pEC50 0.4467 nM
CC(=O)NCCC1CCc2ccc3ncoc3c21 CHEMBL3648354 Ki 0.45 nM
COc1nc2ccc3c(c2o1)C(CCNC(C)=O)CC3 CHEMBL3648367 Ki 0.45 nM
CC(=O)NCCc1c(C(F)(F)F)nn2ccc3c(c12)CCO3 CHEMBL1802029 Ki 0.48 nM
CC(=O)NCCc1cccc2ccc(OCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12 CHEMBL429392 Ki 0.5 nM
CC(=O)NCCC1=C(Cc2ccccc2)Cc2ccc3c(c21)CCO3 CHEMBL1774518 pEC50 0.5129 nM
CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc(-c4ccc(C(=O)O)cc4)cc3)cc12 CHEMBL1094546 Ki 0.55 nM
CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12 CHEMBL14453 Ki 0.6 nM
CC(C)C1Nc2cccc([C@@H]3C[C@H]3CNC(=O)C3CC3)c2O1 CHEMBL18846 Ki 0.6 nM
CC(=O)NC[C@@H]1CC1c1cccc2oc(CCCCc3ccccc3)cc12 CHEMBL186586 EC50 0.6 nM
CNC(=O)NCCc1cccc2ccc(OC)nc12 CHEMBL4084612 Ki 0.6 nM
COCC(=O)NCC1CCc2ccc3ccc(OC)cc3c21 CHEMBL4292336 Ki 0.6 nM
COc1ccc2ccc3c(c2c1)C(C)(CNS(C)(=O)=O)CC3 CHEMBL4288497 Ki 0.6 nM
COc1ccc2c(c1)c(CCNC(C)=O)cn2C(=O)OCc1ccccc1[N+](=O)[O-] CHEMBL5173623 pEC50 0.6166 nM
O=C(NCCCc1cccc2nc(CCCCc3ccccc3)oc12)C1CC1 CHEMBL334079 Ki 0.63 nM
CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4cccc(CCNC(=O)c5ccco5)c4c3)cc12 CHEMBL1096991 Ki 0.64 nM
CCNC(=O)N[C@@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL136564 Ki 0.65 nM
COc1ccc2ccc(OC)c3c2c1CCC3CCNC(=O)C1CC1 CHEMBL131575 Ki 0.66 nM
Cc1nc2cccc(CCCNC(=O)C3CC3)c2o1 CHEMBL127570 Ki 0.7 nM
CCC(=O)NCC1CCc2ccccc2N1C CHEMBL3612604 Ki 0.7 nM
CCOc1nc2ccc(OC)cc2n1CCNC(=O)C1CC1 CHEMBL4869463 Ki 0.71 nM
COc1cccc(O[C@@H](C)CNC(=O)C2CC2)c1 CHEMBL1223130 pKi 0.7244 nM
COc1ccc2oc(Cc3cccc(F)c3)c(CCNC(C)=O)c2c1 CHEMBL95166 Ki 0.75 nM
CCC(=O)NCCCc1cccc2nc(CCCCc3ccccc3)oc12 CHEMBL330969 Ki 0.76 nM
CC(=O)NCCc1c(Br)[nH]c2ccc(OCCCCCCNC(=O)Oc3cccc(-c4ccccc4)c3)cc12 CHEMBL4210086 pKi 0.7762 nM
CCCC(=O)NCC1Cc2cccc3cccc1c23 CHEMBL337882 Ki 0.79 nM
C=CCC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12 CHEMBL1095195 Ki 0.79 nM
CCOc1ccc2cccc(CCNC(C)=O)c2c1 CHEMBL137998 pIC50 0.7943 nM
CCOc1ccc2cccc(CCNC(=O)CC)c2c1 CHEMBL137878 pIC50 0.7943 nM
COc1ccc2[nH]cc(CCNC(=O)C(F)(F)F)c2c1 CHEMBL322762 pIC50 0.7943 nM
COc1ccc2cccc3c2c1CCC3CNC(C)=O CHEMBL336647 Ki 0.8 nM
CCNC(=O)NCCc1cccc2ccc(OC)nc12 CHEMBL4062947 Ki 0.8 nM
COc1ccc2ccc3c(c2c1)C(CNS(C)(=O)=O)CC3 CHEMBL4280601 Ki 0.8 nM
CCNC(=O)NCC1(C)CCc2ccc3ccc(OC)cc3c21 CHEMBL4286896 Ki 0.8 nM
COc1cccc(N(C)CCNC(C)=O)c1 CHEMBL237236 Log Ki 0.8128 nM
COc1cccc(N(C)CCCNC(C)=O)c1 CHEMBL235329 Log Ki 0.8318 nM
CC(=O)NCCc1c(-c2cccc(O)c2)oc2ccc3c(c12)CCCO3 CHEMBL3103594 Ki 0.87 nM
CSc1ccc2cccc(CCNC(C)=O)c2c1 CHEMBL456727 IC50 0.875 nM
CC(=O)NCCC1=C(Cc2ccsc2)Cc2ccc3c(c21)CCO3 CHEMBL1774520 Ki 0.88 nM
CNC(=O)N[C@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL138012 Ki 0.9 nM
CCCNC(=O)NCC1CCc2ccc3ccc(OC)nc3c21 CHEMBL4278446 EC50 0.9 nM
C=CCC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4cccc(CCNC(=O)CC=C)c4c3)cc12 CHEMBL1097315 Ki 0.92 nM
COc1cccc(OC(C)CNC(=O)C2CC2)c1 CHEMBL1223128 pKi 0.9333 nM
CCOc1nc2cc(Cl)c(OC)cc2n1CCCNC(C)=O CHEMBL4846505 EC50 0.937 nM
CCCC(=O)NC[C@@H]1C[C@H]1c1cccc2c1OC(CCC)N2 CHEMBL19211 Ki 0.94 nM
COc1ccc2cccc3c2c1CCC3CNC(=O)C1CC1 CHEMBL130876 Ki 0.95 nM
CCCC1Nc2cccc([C@@H]3C[C@H]3CNC(C)=O)c2O1 CHEMBL19128 Ki 0.96 nM
CCOc1nc2ccc(OC)cc2n1CCNC(=O)CC CHEMBL4872217 EC50 0.97 nM
COc1ccc2[nH]c(Sc3ccccc3)c(CCNC(C)=O)c2c1 CHEMBL5407163 pKi 0.9772 nM
COc1ccc2c(c1)c1c(n2C)CCCC1NC(C)=O CHEMBL38728 pIC50 1.0 nM
CCC(=O)Nc1ccc(N(C)c2cccc(OC)c2)cc1 CHEMBL7832 Ki 1.0 nM
CC(=O)NCCc1coc2ccc3c(c12)CCCO3 CHEMBL138321 pIC50 1.0 nM
CC(=O)NC[C@@H]1C[C@H]1c1cccc2c1C[C@@H](CCCCc1ccccc1)O2 CHEMBL359921 Ki 1.0 nM
CCC(=O)NC[C@@H]1C[C@H]1c1cccc2c1C[C@@H](CCCCc1ccccc1)O2 CHEMBL367797 Ki 1.0 nM
O=C(NC[C@@H]1C[C@H]1c1cccc2c1C[C@@H](CCCCc1ccccc1)O2)C1CC1 CHEMBL361410 Ki 1.0 nM
CCC(=O)NCCCc1cccc2c1C[C@@H](CCCCc1ccccc1)O2 CHEMBL178678 Ki 1.0 nM
COc1ccc2ccc3occ(CNC(=O)C4CC4)c3c2c1 CHEMBL3759816 EC50 1.0 nM
COc1ccc2ccc3oc(CNC(=O)C4CC4)cc3c2c1 CHEMBL3758679 EC50 1.0 nM
CNC(=S)NCC1(C)CCc2ccc3ccc(OC)cc3c21 CHEMBL4280791 Ki 1.0 nM
C/C=C/C(=O)NCCc1c(-c2ccccc2)oc2ccc(OC)cc12 CHEMBL96104 Ki 1.01 nM
O=C(NCCc1cccc2ccc(OCCCCOc3ccc4cccc(CCNC(=O)C5CC5)c4c3)cc12)C1CC1 CHEMBL1097314 Ki 1.01 nM
O=C(NCC1Cc2cccc3cccc1c23)C1CC1 CHEMBL341439 Ki 1.06 nM
CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4cccc(CCNC(=O)C5CC5)c4c3)cc12 CHEMBL1095832 Ki 1.07 nM
CCCC(=O)Nc1ccc(N(C)c2cccc(OC)c2)cc1 CHEMBL266549 Ki 1.1 nM
COc1cc2c(CCNC(C)=O)c(I)n(C)c2cc1[N+](=O)[O-] CHEMBL55084 Ki 1.1 nM
COc1ccccc1C1=C(CCNC(C)=O)c2c(ccc3c2CCO3)C1 CHEMBL1774525 Ki 1.1 nM
CCNC(=O)NCCC1=C(C(C)C)Cc2ccc3c(c21)CCO3 CHEMBL1774517 Ki 1.1 nM
COc1ccc2[nH]cc(C(C)(C)CNC(C)=O)c2c1 CHEMBL206472 Ki 1.12 nM
CC(=O)NCCN(C)c1cccc(OCCCCc2ccccc2)c1 CHEMBL3260987 Ki 1.17 nM
O=C(N[C@H]1CCN(c2cccc3c2CCO3)C1)C1CC1 CHEMBL139439 Ki 1.2 nM
CC(=O)NCC1CCc2cccc3cccc1c23 CHEMBL130319 Ki 1.2 nM
CCCCCCOc1ccc2c(c1)C(CCNC(C)=O)CCO2 CHEMBL3260984 Ki 1.2 nM
O=C(NCCc1cccc2ccc(OCCCOc3ccc4cccc(CCNC(=O)C(F)F)c4c3)cc12)C(F)F CHEMBL3741890 Ki 1.2 nM
CC(=O)NCCC1CCc2ccc3nc(CO)oc3c21 CHEMBL4848381 Ki 1.2 nM
COc1ccc2c(c1)c(C(C)CNC(C)=O)cn2C CHEMBL210791 Ki 1.22 nM
COc1ccc2scc(CCNC(C)=O)c2c1 CHEMBL109235 pIC50 1.259 nM
COc1ccc2cccc(CCNC(=O)C3CC3)c2c1 CHEMBL417151 pIC50 1.259 nM
CC(=O)NCCc1cccc2ccc3occc3c12 CHEMBL11404 pIC50 1.259 nM
COc1ccc2[nH]cc(CCNC(=O)CI)c2c1 CHEMBL113441 pIC50 1.259 nM
CCCC(=O)NCC1Cc2ccccc2Cc2ccc(OC)cc21 CHEMBL189395 Log Ki 1.288 nM
CC(=O)NCCCc1cccc2nc(CCCCc3ccccc3)oc12 CHEMBL339265 Ki 1.3 nM
CC(C)C(=O)NCCCc1cccc2nc(CCCCc3ccccc3)oc12 CHEMBL435586 Ki 1.3 nM
CCC(=O)NCCc1c(OC(=O)CBr)ccc2ccc(OC)cc12 CHEMBL134416 Ki 1.3 nM
CC(C)C(=O)NC[C@@H]1C[C@H]1c1cccc2c1OC(C(C)C)N2 CHEMBL19441 Ki 1.3 nM
CCCC(=O)NCC1CCc2cccc3cccc1c23 CHEMBL338425 Ki 1.3 nM
CCCC(=O)NCCn1ccc2ccc(OC)nc21 CHEMBL1760947 Ki 1.3 nM
CC(=O)NCCC1=C(c2csc3ccccc23)Cc2ccc3c(c21)CCO3 CHEMBL1774531 Ki 1.3 nM
CC(=O)NCCC1CCc2ccc3nc(-c4ccccc4)oc3c21 CHEMBL4864102 Ki 1.3 nM
COc1ccc2cccc3c2c1C(CNC(=O)C1CC1)C3 CHEMBL334962 Ki 1.32 nM
COc1cc2c(CCNC(C)=O)c(C)[nH]c2cc1Cl CHEMBL3260979 Ki 1.34 nM
CCC(=O)NCC1Cc2ccccc2Cc2ccc(OC)cc21 CHEMBL189414 Log Ki 1.349 nM
CCC(=O)NCC(CO)c1cccc2ccc(OC)cc12 CHEMBL4097233 pKi 1.349 nM
CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4occ(CCNC(C)=O)c4c3)cc12 CHEMBL1097496 Ki 1.38 nM
COc1ccc2ccn(CCNC(C)=O)c2n1 CHEMBL1760945 Ki 1.4 nM
CC(=O)NCCC1=C(c2ccc(C(C)(C)C)cc2)Cc2ccc3c(c21)CCO3 CHEMBL1774530 Ki 1.4 nM
CC(=O)NCCc1c(Br)[nH]c2ccc(OCCO)cc12 CHEMBL4548591 pKi 1.445 nM
CC(=O)N[C@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL336268 Ki 1.5 nM
CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4cc(C(C)C(=O)O)ccc4c3)cc12 CHEMBL1095505 Ki 1.51 nM
CC(=O)NCC1Cc2ccccc2N(c2ccccc2)C1 CHEMBL4074273 Ki 1.58 nM
CCC(=O)NCC1CCc2ccccc2N1c1ccccc1 CHEMBL3612608 Ki 1.6 nM
COc1ccc2occ(CCNC(C)=O)c2n1 CHEMBL3763281 Ki 1.6 nM
CC(C)=CCC/C(C)=C/CC/C(C)=C/COc1ccc2ccc(=O)oc2c1 CHEMBL156127 KiH 1.6 nM
COc1ccc2[nH]cc(C(C)CNC(C)=O)c2c1 CHEMBL210147 Ki 1.67 nM
COc1cccc(O[C@@H](C)CNC(C)=O)c1 CHEMBL1223050 pKi 1.698 nM
CCC(=O)NCCc1c[nH]c2c(C)cc(OC)cc12 CHEMBL395221 Log Ki 1.778 nM
CCCC(=O)NC[C@@H]1C[C@H]1c1cccc2c1OC(C(C)C)N2 CHEMBL553105 Ki 1.8 nM
COc1ccc2c(c1)c(CCNC(C)=O)c1n2Cc2ccccc2-1 CHEMBL9772 Ki 1.82 nM
COc1ccc2cccc3c2c1CCC3CCNC(=O)C1CC1 CHEMBL336633 Ki 1.89 nM
COc1ccc2cccc(C(CO)CNC(=O)C(F)F)c2c1 CHEMBL4104020 pKi 1.905 nM
CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4scc(CCNC(C)=O)c4c3)cc12 CHEMBL1097497 EC50 1.94 nM
COc1cc2c(CCNC(=O)C3CC3)c[nH]c2cc1F CHEMBL109086 pIC50 1.995 nM
C=CCOc1ccc2cccc(CCNC(=O)CC)c2c1 CHEMBL138766 pIC50 1.995 nM
CCC(=O)NCCc1cccc2ccc(OC)cc12 CHEMBL37771 pIC50 1.995 nM
CCCC(=O)NC[C@@H]1C[C@H]1c1cccc2c1C[C@@H](CCCCc1ccccc1)O2 CHEMBL367604 Ki 2.0 nM
CCCC(=O)NCCCc1cccc2c1C[C@@H](CCCCc1ccccc1)O2 CHEMBL368886 Ki 2.0 nM
O=C(NCCCc1cccc2c1C[C@@H](CCCCc1ccccc1)O2)C1CC1 CHEMBL181974 Ki 2.0 nM
CCCN1c2ccccc2CCC1CNC(C)=O CHEMBL3612606 EC50 2.0 nM
COc1ccc2cccc(CCNC(N)=O)c2n1 CHEMBL4071572 Ki 2.0 nM
CNC(=S)NCCc1cccc2ccc(OC)nc12 CHEMBL4095210 Ki 2.0 nM
COC(=O)NCC1CCc2ccc3ccc(OC)cc3c21 CHEMBL4285145 Ki 2.0 nM
CCNC(=O)NCC1CCc2ccc3ccc(OC)cc3c21 CHEMBL4290302 Ki 2.0 nM
CCCNC(=O)NCC1(C)CCc2ccc3ccc(OC)cc3c21 CHEMBL4291381 Ki 2.0 nM
CC(=O)NCCc1cccc2ccc(OCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12 CHEMBL14514 Ki 2.05 nM
CCC(=O)NCCC1CCc2c(OC)ccc3cccc1c23 CHEMBL340745 Ki 2.08 nM
CCC(=O)NC[C@@H]1CC1c1cccc2oc(CCCCc3ccccc3)cc12 CHEMBL186736 Ki 2.1 nM
COc1ccc2ccc3oc(CNC(C)=O)cc3c2c1 CHEMBL3758717 Ki 2.1 nM
CNC(=O)N[C@@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL344449 Ki 2.2 nM
CCCC(=O)NCCc1ccnc2ccc(OC)cc12 CHEMBL68864 Ki 2.2 nM
CCC(=O)NCCc1c(O)ccc2ccc(OC)cc12 CHEMBL440692 Ki 2.2 nM
COc1ccc2oc(-c3ccc4ccccc4c3)c(CCNC(C)=O)c2n1 CHEMBL3764765 Ki 2.2 nM
COc1ccc2c(c1)c(CCNC(C)=O)cn2C CHEMBL33700 Log Ki 2.239 nM
CCCC(=O)NCCCc1cccc2nc(C)oc12 CHEMBL338659 Ki 2.3 nM
CCCNC(=O)CCCc1cccc2c1SCCO2 CHEMBL3260981 IC50 2.3 nM
COC(=O)c1ccc(-c2ccc(OCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc2)cc1 CHEMBL1094545 Ki 2.37 nM
CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4[nH]cc(CCNC(C)=O)c4c3)cc12 CHEMBL1095522 EC50 2.38 nM
CCC(=O)N[C@H]1CCN(c2cccc3oc(CCCCc4ccccc4)cc23)C1 CHEMBL186977 Ki 2.4 nM
C=CCNC(=O)CCc1c[nH]c2ccc(OC)cc12 CHEMBL3580910 Ki 2.5 nM
COc1ccc2cccc(CCNC(=O)C(C)C)c2c1 CHEMBL37703 pIC50 2.512 nM
CNC(=O)NCCc1cccc2ccc(OC)cc12 CHEMBL138817 pIC50 2.512 nM
CCC(=O)NCC1Cc2cccc3cccc1c23 CHEMBL133001 Ki 2.65 nM
COc1cccc(/C(=C/CNC(C)=O)c2ccccc2)c1 CHEMBL218708 Log Ki 2.692 nM
COc1cc(C)c2[nH]cc(CCNC(C)=O)c2c1 CHEMBL231872 Log Ki 2.692 nM
CCC(=O)NCCCc1cccc2nc(C)oc12 CHEMBL124577 Ki 2.8 nM
COc1ccc2ccc3occ(CCNC(C)=O)c3c2c1 CHEMBL3759802 Ki 2.8 nM
CCCC(=O)NCCc1c[nH]c2c(C)cc(OC)cc12 CHEMBL391350 Log Ki 2.884 nM
CCC(=O)NCCCc1cc(OC)ccc1-c1cccc(OC)c1 CHEMBL2326203 EC50 2.94 nM
Cc1nc2cccc(CCCNC(=O)C(C)C)c2o1 CHEMBL127596 Ki 3.0 nM
COc1ccc(C2=C(CCNC(C)=O)c3c(ccc4c3CCO4)C2)cc1 CHEMBL1774527 Ki 3.0 nM
CNC(=S)NCC1CCc2ccc3ccc(OC)cc3c21 CHEMBL4281915 Ki 3.0 nM
COc1ccc2c(c1)C(CNC(C)=O)Cc1ccccc1C2=O CHEMBL427516 Log Ki 3.02 nM
CC(=O)NCCC1=C(c2cccc(C(C)C)c2)Cc2ccc3c(c21)CCO3 CHEMBL1774529 pEC50 3.02 nM
CCCC(=O)NC[C@H](C)Oc1cccc(OC)c1 CHEMBL1223195 pKi 3.09 nM
CCNC(=O)NC[C@@H]1C[C@H]1c1cccc2c1OC(CC)N2 CHEMBL19260 Ki 3.1 nM
CNC(=O)N/C=C/c1c(OC)ccc2ccccc12 CHEMBL2314258 Ki 3.1 nM
CCCC(=O)NCCc1c2n(c3ccc(OC)cc13)CCN(C)C2 CHEMBL556908 IC50 3.14 nM
CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4cccc(CC(=O)O)c4c3)cc12 CHEMBL1095504 EC50 3.14 nM
CCCOc1ccc2cccc(CCNC(=O)CC)c2c1 CHEMBL140549 pIC50 3.162 nM
CNC(=O)NCCc1coc2ccc(OC)cc12 CHEMBL141115 pIC50 3.162 nM
C=CCc1c(O)ccc2cccc(CCNC(=O)CC)c12 CHEMBL436006 pIC50 3.162 nM
CCCC(=O)NCCc1c(Cc2ccccc2)oc2ccc(OC)cc12 CHEMBL96859 Ki 3.29 nM
CCCC(=O)NCCCc1cccc2nc(CCCCc3ccccc3)oc12 CHEMBL125705 Ki 3.3 nM
CCC(=O)NCCn1ccc2ccc(OC)nc21 CHEMBL1760946 Ki 3.3 nM
CC(=O)NCCN(C)c1cccc(OCCCCCCOc2cccc(N(C)CCNC(C)=O)c2)c1 CHEMBL1813321 pKi 3.388 nM
CCC(=O)NC[C@H](CO)c1cccc2ccc(OC)cc12 CHEMBL4074895 pKi 3.388 nM
CCC(=O)NC[C@@H]1CN(C)c2ccccc2[C@@H]1c1ccccc1 CHEMBL4068887 Ki 3.4 nM
CCC(=O)NCCCc1cccc2nc(CC)oc12 CHEMBL124362 Ki 3.5 nM
CCCC1Nc2cccc([C@@H]3C[C@H]3CNC(=O)NCC)c2O1 CHEMBL19109 Ki 3.5 nM
CCC(=O)NC[C@@H]1CCc2ccccc2[C@@H]1c1ccccc1 CHEMBL4083618 Ki 3.5 nM
C=CCC(=O)NCCc1c(Cc2ccccc2)oc2ccc(OC)cc12 CHEMBL97186 Ki 3.51 nM
COc1cc(Br)c2[nH]cc(CCNC(C)=O)c2c1 CHEMBL233728 Log Ki 3.548 nM
CCOc1nc2ccc(OC)cc2n1CCNC(=O)C1CCC1 CHEMBL4860729 EC50 3.58 nM
COc1cccc(OC(C)CNC(C)=O)c1 CHEMBL1222986 pKi 3.631 nM
CCCC(=O)N[C@H]1CCN(c2cccc(OC)c2)C1 CHEMBL139497 Ki 3.7 nM
CC(C)C(=O)NCCCc1cccc2oc(CCCCc3ccccc3)cc12 CHEMBL187186 Ki 3.7 nM
COc1ccc2ccccc2c1[C@@H]1C[C@H]1NC(C)=O CHEMBL2314252 Ki 3.7 nM
CCCC(=O)NC[C@H](C)Sc1cccc(OC)c1 CHEMBL1223198 pKi 3.89 nM
O=C(N[C@@H]1CCN(c2cccc3c2CCO3)C1)C1CC1 CHEMBL138228 Ki 3.9 nM
CC(=O)NCCc1c[nH]c2ccc(OCCCc3ccccc3)cc12 CHEMBL3260985 Ki 3.9 nM
COc1ccc2cccc(CCNC(N)=O)c2c1 CHEMBL335116 pIC50 3.981 nM
CCCC(=O)NOCc1cccc2ccc(OC)cc12 CHEMBL441664 pIC50 3.981 nM
CC(=O)NCCc1coc2ccc3c(c12)C=CCO3 CHEMBL337580 pIC50 3.981 nM
COc1ccc2scc(CCNC(=O)C3CC3)c2c1 CHEMBL321612 pIC50 3.981 nM
CC(=O)NCCN(C)c1cccc(OCCCCCCCCCCOc2cccc(N(C)CCNC(C)=O)c2)c1 CHEMBL1813323 pKi 3.981 nM
CC(=O)NCCCc1cccc2c1C[C@@H](CCCCc1ccccc1)O2 CHEMBL362849 Ki 4.0 nM
CC(C)C(=O)NCCCc1cccc2c1C[C@@H](CCCCc1ccccc1)O2 CHEMBL181687 Ki 4.0 nM
CCNC(=S)NCCc1cccc2ccc(OC)nc12 CHEMBL4079699 Ki 4.0 nM
COc1ccc2ccc3c(c2c1)C(CCNC(C)=O)CC3 CHEMBL4288925 Ki 4.0 nM
CCNC(=S)NCC1(C)CCc2ccc3ccc(OC)cc3c21 CHEMBL4292109 Ki 4.0 nM
CCCC(=O)NCCc1c2n(c3ccc(OC)cc13)CCc1ccccc1-2 CHEMBL10099 Ki 4.07 nM
CCC(=O)NCCc1c[nH]c2c(Br)cc(OC)cc12 CHEMBL233729 Log Ki 4.169 nM
CCCC(=O)NCCN(c1ccccc1)c1cccc(OC)c1 CHEMBL279401 Log Ki 4.169 nM
COc1cccc(N(CCNC(C)=O)c2ccccc2)c1 CHEMBL235327 Log Ki 4.169 nM
CCCC(=O)NCC(C)Oc1cccc(OC)c1 CHEMBL1223193 pKi 4.169 nM
CC(=O)NCC1Cc2cccc3cccc1c23 CHEMBL131602 Ki 4.24 nM
CCCC(=O)NCC(C)c1cn(C)c2ccc(OC)cc12 CHEMBL377101 Ki 4.27 nM
CCC(=O)NCCc1c(OCCO)ccc2ccc(OC)cc12 CHEMBL78751 Ki 4.3 nM
CCC(=O)NCCC1Cc2cccc3cccc1c23 CHEMBL336333 Ki 4.34 nM
CCC(=O)NCCc1c2n(c3ccc(OC)cc13)Cc1ccccc1-2 CHEMBL274317 Ki 4.37 nM
CCCNC(=O)N[C@@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL342393 Ki 4.4 nM
CC(=O)NCCC1CCc2ccc3nc(Cc4ccccc4)oc3c21 CHEMBL4870108 Ki 4.4 nM
CC(=O)NCCC1=C(CC2CCCCC2)Cc2ccc3c(c21)CCO3 CHEMBL1774519 pEC50 4.467 nM
CCCC(=O)NCCc1c2n(c3ccc(OC)cc13)Cc1ccccc1-2 CHEMBL10009 Ki 4.47 nM
CCc1nc2cccc(CCCNC(=O)C3CC3)c2o1 CHEMBL125642 Ki 4.5 nM
COc1ccc2ccc3occ(CNC(C)=O)c3c2c1 CHEMBL3758225 Ki 4.6 nM
COc1ccc2cccc(C(CO)CNC(=O)CF)c2c1 CHEMBL4095334 pKi 4.677 nM
CC(=O)NCCc1c[nH]c2ccc(OCCCCCCCCNC(=O)Oc3cccc(-c4ccccc4)c3)cc12 CHEMBL4202816 pKi 4.898 nM
CCC(=O)NC[C@@H]1C[C@H]1c1cccc2c1OC(C(C)C)N2 CHEMBL428692 Ki 4.9 nM
CCCC1Nc2cccc([C@@H]3C[C@H]3CNC(=O)C(C)C)c2O1 CHEMBL19050 Ki 4.9 nM
CCC(=O)NCC(C)c1cn(C)c2ccc(OC)cc12 CHEMBL379616 Ki 4.9 nM
C#CCNC(=O)CCc1c[nH]c2ccc(OC)cc12 CHEMBL3580908 Ki 5.0 nM
CCNC(=O)NCC1CCc2c(OC)cccc2N1C CHEMBL3612461 Ki 5.0 nM
COc1ccc2cccc(CCNC(=O)C(F)(F)F)c2c1 CHEMBL322339 Ki 5.0 nM
COc1ccc2cccc(CCNC(=O)C(Cl)Cl)c2c1 CHEMBL3742090 Ki 5.0 nM
COc1ccc2cccc(CCC(=O)NS(C)(=O)=O)c2n1 CHEMBL4089965 Ki 5.0 nM
COc1ccc2ccc3c(c2n1)C(CCNC(C)=O)CC3 CHEMBL4277185 Ki 5.0 nM
CCCNC(=O)NCC1CCc2ccc3ccc(OC)cc3c21 CHEMBL4294790 Ki 5.0 nM
COc1ccc2scc(CCNC(=O)CI)c2c1 CHEMBL320253 pIC50 5.012 nM
COc1ccc2cccc(C(O)CNC(C)=O)c2c1 CHEMBL138440 pIC50 5.012 nM
COc1ccc2occ(CCNC(=O)C3CC3)c2c1 CHEMBL110980 pIC50 5.012 nM
C#CCOc1ccc2cccc(CCNC(C)=O)c2c1 CHEMBL137910 pIC50 5.012 nM
COc1ccc2ccc3c(c2c1)CC(NC(C)=O)CO3 CHEMBL138752 pIC50 5.012 nM
CC(=O)NC[C@@H]1C[C@H]1c1cccc2c1OC(C(C)C)N2 CHEMBL278922 Ki 5.1 nM
CCCC(=O)NCCc1c[nH]c2c(Br)cc(OC)cc12 CHEMBL233308 Log Ki 5.129 nM
CC(=O)NCCc1cccc2ccc(-c3ccc4cccc(CCNC(C)=O)c4c3)cc12 CHEMBL1097525 Ki 5.2 nM
COc1ccc2ccc3occ(CCNC(=O)C4CC4)c3c2c1 CHEMBL3759606 EC50 5.2 nM
COc1cccc(NCCNC(C)=O)c1 CHEMBL398017 Log Ki 5.248 nM
CCNC(=O)NCC1CCc2ccccc2N1C CHEMBL3612462 Ki 5.3 nM
CNC(=O)NCCc1c(Cc2ccccc2)oc2ccc(OC)cc12 CHEMBL94301 Ki 5.37 nM
COc1cccc(S[C@@H](C)CNC(=O)C2CC2)c1 CHEMBL1223192 pKi 5.37 nM
CCC(=O)NCCc1c(CN2Cc3ccccc3C2)[nH]c2ccc(OC)cc12 CHEMBL3219327 pKi 5.623 nM
COc1ccc2ccc3oc(CNC(=O)CF)cc3c2c1 CHEMBL3759084 Ki 5.7 nM
COc1ccc2c(c1)CCN2Cc1[nH]c2ccc(OC)cc2c1CCNC(C)=O CHEMBL515856 pKi 5.754 nM
COc1cccc(S[C@@H](C)CNC(C)=O)c1 CHEMBL1223053 pKi 5.754 nM
COc1ccc2cccc([C@@H](CO)CNC(=O)CF)c2c1 CHEMBL4087633 pKi 5.888 nM
CCC(=O)NCCc1c2n(c3ccc(OC)cc13)CCc1ccccc1-2 CHEMBL9997 Ki 5.89 nM
COc1ccc2nccc(CCNC(C)=O)c2c1 CHEMBL69521 Ki 5.9 nM
COc1ccc2cc(-c3ccccc3CO)cc(CCNC(C)=O)c2c1 CHEMBL517502 Ki 5.9 nM
CC(C)C(=O)N[C@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL138744 Ki 6.0 nM
CC(C)C(=O)NC[C@@H]1C[C@H]1c1cccc2c1C[C@@H](CCCCc1ccccc1)O2 CHEMBL361854 Ki 6.0 nM
O=C(NCCCc1cccc2oc(CCCCc3ccccc3)cc12)C1CC1 CHEMBL183846 Ki 6.0 nM
COc1ccc2ccc3c(c2c1)C(CNC(N)=S)CC3 CHEMBL4289115 Ki 6.0 nM
CC(=O)NCCc1c[nH]c2ccc(OCCCCCCNC(=O)Oc3cccc(-c4ccccc4)c3)cc12 CHEMBL4214478 pKi 6.026 nM
CCC(=O)NCC(C)(C)c1cn(C)c2ccc(OC)cc12 CHEMBL426127 Ki 6.03 nM
COc1ccc2c(c1)C(CNC(C)=O)Cc1ccccc1C2 CHEMBL189449 Log Ki 6.166 nM
O=C(NCCc1c[nH]c2ccc(OCCCOc3ccccc3)cc12)C(F)F CHEMBL3739674 pKi 6.166 nM
CCCCCOc1ccc2cccc(CCNC(=O)CC)c2c1 CHEMBL139014 pIC50 6.31 nM
CCCCC(=O)NCCc1coc2ccc(OC)cc12 CHEMBL111718 pIC50 6.31 nM
CCCc1cc(CCNC(C)=O)c2cc(OC)ccc2c1 CHEMBL139410 pIC50 6.31 nM
CCCC(=O)NCCC1Cc2cccc3cccc1c23 CHEMBL133426 Ki 6.41 nM
O=C(NCCC1Cc2cccc3cccc1c23)C1CC1 CHEMBL131431 Ki 6.48 nM
CC(=O)NCCC1Cc2cccc3cccc1c23 CHEMBL337295 Ki 6.5 nM
CCC(=O)NCCCc1cccc2ncoc12 CHEMBL124476 Ki 6.6 nM
O=C(NC1CC1)N[C@@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL435023 Ki 6.6 nM
CC(=O)N/C=C/c1cccc2ccccc12 CHEMBL229015 Ki 6.7 nM
CCC(=O)NCCc1ccnc2ccc(OC)cc12 CHEMBL306468 Ki 6.9 nM
CCNC(=O)N[C@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL136431 Ki 7.0 nM
COC(=O)NCCc1cccc2ccc(OC)nc12 CHEMBL4082097 Ki 7.0 nM
CCS(=O)(=O)NCC1CCc2ccc3ccc(OC)cc3c21 CHEMBL4286494 Ki 7.0 nM
COc1ccc2oc(Cc3cccc(Cl)c3)c(CCNC(C)=O)c2c1 CHEMBL94607 Ki 7.19 nM
COc1ccc2c(c1)c(CCNC(C)=O)c1n2CCc2ccccc2-1 CHEMBL274842 Ki 7.24 nM
COc1cccc(OCCNC(C)=O)c1 CHEMBL396132 Log Ki 7.244 nM
CCC(=O)NCCCc1cccc2oc(CCCCc3ccccc3)cc12 CHEMBL363936 Ki 7.5 nM
CCCCOc1ccc2ccc(OC)cc2c1CCNC(=O)CC CHEMBL82135 Ki 7.7 nM
COc1cccc(O[C@H](C)CNC(=O)C2CC2)c1 CHEMBL1223129 pKi 7.762 nM
COc1ccc2c(c1)c(CCNC(C)=O)cn2C(=O)OCc1cc(OC)c(OC)cc1[N+](=O)[O-] CHEMBL5195595 pKi 7.762 nM
CC(=O)NCCc1c[nH]c2ccc(OCCCOc3ccccc3)cc12 CHEMBL3260986 Ki 7.9 nM
COc1ccc2[nH]c(C(=O)OCCCCCCCCOC(=O)c3[nH]c4ccc(OC)cc4c3CCNC(C)=O)c(CCNC(C)=O)c2c1 CHEMBL387655 Ki 7.91 nM
CCNC(=O)NCCc1coc2ccc(OC)cc12 CHEMBL344268 pIC50 7.943 nM
COc1ccc2cccc(CONC(C)=O)c2c1 CHEMBL138549 pIC50 7.943 nM
COc1ccc2cc(CC3CC3)cc(CCNC(C)=O)c2c1 CHEMBL342432 pIC50 7.943 nM
COc1ccc2occ(CCNC(=O)CI)c2c1 CHEMBL342655 pIC50 7.943 nM
CCC(=O)NCCc1cccc2ccc(OCC3CC3)cc12 CHEMBL336010 pIC50 7.943 nM
COc1ccc(N(C)Cc2[nH]c3ccc(OC)cc3c2CCNC(C)=O)cc1 CHEMBL552002 Ki 8.0 nM
CNC(=O)CCc1cccc2ccc(OC)nc12 CHEMBL4079784 Ki 8.0 nM
CCCC(=O)NCCCc1cccc2nc(CC)oc12 CHEMBL124422 Ki 8.1 nM
CCCOc1ccc2ccc(OC)cc2c1CCNC(=O)CC CHEMBL311106 Ki 8.1 nM
COc1ccc2ccc3occ(CNC(=O)C(C)C)c3c2c1 CHEMBL3759054 EC50 8.1 nM
CCCCCCOc1ccc2oc(Cc3ccccc3)c(CCNC(C)=O)c2c1 CHEMBL315653 Ki 8.2 nM
COc1ccc2[nH]cc(C3(CNC(C)=O)CCC3)c2c1 CHEMBL207960 Ki 8.2 nM
CCC(=O)NCCCc1cc(OC)ccc1C#Cc1cccc(OC)c1 CHEMBL2326200 EC50 8.38 nM
CCCC(=O)NCC(C)(C)c1cn(C)c2ccc(OC)cc12 CHEMBL207745 Ki 8.51 nM
COc1cccc(SC(C)CNC(=O)C2CC2)c1 CHEMBL1223131 pKi 8.511 nM
COc1ccc2oc(Cc3ccccc3)c(CCNC(=O)CI)c2c1 CHEMBL328617 Ki 8.67 nM
COc1cc(C)c2c(c1)c(CCNC(C)=O)cn2C CHEMBL392421 Log Ki 8.71 nM
COc1ccc2cccc3c2c1CCC3CCNC(C)=O CHEMBL130286 Ki 8.9 nM
CCCC(=O)NCCc1c2n(c3ccc(OCC)cc13)Cc1ccccc1-2 CHEMBL9590 Ki 8.91 nM
CCc1nc2cccc(CCCNC(C)=O)c2o1 CHEMBL125665 Ki 9.0 nM
CCNC(=O)NC[C@@H]1C[C@H]1c1cccc2c1C[C@@H](CCCCc1ccccc1)O2 CHEMBL361206 Ki 9.0 nM
CCNC(=O)NCCCc1cccc2c1C[C@@H](CCCCc1ccccc1)O2 CHEMBL181192 Ki 9.0 nM
COc1ccc2c3c(n(CCNC(C)=O)c2n1)CCCC3 CHEMBL1760957 Ki 9.0 nM
CC(=O)NCCc1cccc2ccc(OCCCc3ccccc3)cc12 CHEMBL3739824 Ki 9.0 nM
CC(=O)NCCc1cccc2ccc(OCCCCc3ccccc3)cc12 CHEMBL3741561 Ki 9.0 nM
CCCNC(=S)NCC1(C)CCc2ccc3ccc(OC)cc3c21 CHEMBL4284223 Ki 9.0 nM
CCC(=O)NCCCc1cc(OC)ccc1OCc1cccc(OC)c1 CHEMBL2326199 EC50 9.03 nM
CCCC(=O)NCC(C)Sc1cccc(OC)c1 CHEMBL1223196 pKi 9.12 nM
CC(=O)NCCC1CCc2ccn3nc(C)c(C)c3c21 CHEMBL4871181 Ki 9.3 nM
COc1ccc2[nH]c(C(=O)OCCCOC(=O)c3[nH]c4ccc(OC)cc4c3CCNC(C)=O)c(CCNC(C)=O)c2c1 CHEMBL226112 Ki 9.5 nM
COc1cc2c(CCNC(C)=O)c[nH]c2cn1 CHEMBL3765249 Ki 9.5 nM
COc1ccc2[nH]c(CN3c4ccccc4C[C@H]3CO)c(CCNC(C)=O)c2c1 CHEMBL498493 Ki 9.8 nM
CCCC(=O)NCCCc1cccc2ncoc12 CHEMBL124914 Ki 9.9 nM
COc1ccc2ccc3occ(CNC(=O)CF)c3c2c1 CHEMBL3759160 Ki 9.9 nM