CCC(=O)NCCCc1cc(OC)ccc1OCc1ccccc1 CHEMBL1091161 Ki 0.00055 nM
COc1cccc(COc2ccc(OC)cc2CCCNC(C)=O)c1 CHEMBL1092646 Ki 0.00069 nM
COc1ccc2[nH]c(CN3CCc4ccccc43)c(CCNC(=O)C3CCC3)c2c1 CHEMBL445427 pKi 0.001 nM
CCCC(=O)NCCCc1cc(OC)ccc1OCc1ccccc1 CHEMBL1088825 Ki 0.00103 nM
CC(=O)NCCC1=C(c2csc3ccccc23)Cc2ccc3c(c21)CCO3 CHEMBL1774531 Ki 0.006 nM
CC(=O)NCCC1=C(c2ccccc2)Cc2ccc3c(c21)CCO3 CHEMBL1774522 Ki 0.0065 nM
CC(=O)NCCC1=C(Cc2ccsc2)Cc2ccc3c(c21)CCO3 CHEMBL1774520 Ki 0.0067 nM
CC(=O)NCCC1=C(Cc2ccccc2)Cc2ccc3c(c21)CCO3 CHEMBL1774518 Ki 0.0085 nM
COc1cccc(C2=C(CCNC(C)=O)c3c(ccc4c3CCO4)C2)c1 CHEMBL1774526 Ki 0.009 nM
CC(=O)NCCC1=C(c2ccoc2)Cc2ccc3c(c21)CCO3 CHEMBL1774523 Ki 0.0096 nM
C=CC(=O)NCCc1c(-c2ccccc2)oc2ccc(OC)cc12 CHEMBL314512 Ki 0.01 nM
CC(C)C1=C(CCNC(=O)C(F)(F)F)c2c(ccc3c2CCO3)C1 CHEMBL1774516 Ki 0.01 nM
CC(=O)NCCC1=C(c2cccc(C(C)C)c2)Cc2ccc3c(c21)CCO3 CHEMBL1774529 Ki 0.011 nM
CCC(=O)NCCC1=C(C(C)C)Cc2ccc3c(c21)CCO3 CHEMBL1774514 Ki 0.011 nM
CC(=O)NCCC1=C(CC2CCCCC2)Cc2ccc3c(c21)CCO3 CHEMBL1774519 Ki 0.012 nM
CC(=O)NCCC1=C(Br)Cc2ccc3c(c21)CCO3 CHEMBL1774521 Ki 0.014 nM
CCC(=O)NC1Cc2ccccc2C(c2ccccc2)C1 CHEMBL285718 Log Ki 0.01585 nM
CC(=O)NCCC1=C(C(C)C)Cc2ccc3c(c21)CCO3 CHEMBL1774513 Ki 0.018 nM
COc1ccc2oc(-c3ccccc3)c(CCNC(C)=O)c2c1 CHEMBL287560 Ki 0.02 nM
C=CCC(=O)NCCc1c(-c2ccccc2)oc2ccc(OC)cc12 CHEMBL330137 Ki 0.02 nM
COc1ccccc1C1=C(CCNC(C)=O)c2c(ccc3c2CCO3)C1 CHEMBL1774525 Ki 0.02 nM
CC(=O)NCCC1=CCc2ccc3c(c21)CCO3 CHEMBL1774512 Ki 0.022 nM
CCC(=O)NCCCc1cc(OC)ccc1CCc1cccc(OC)c1 CHEMBL2326201 EC50 0.024 nM
COc1cccc(N(CCNC(C)=O)c2cccc(OC)c2)c1 CHEMBL394273 Log Ki 0.02754 nM
COc1ccc2cccc(/C=C/NC(C)=O)c2c1 CHEMBL2314255 Ki 0.03 nM
COc1ccc2oc(-c3ccc(F)cc3)c(CCNC(C)=O)c2n1 CHEMBL3763503 Ki 0.03 nM
COc1ccc2cccc(CCC(=O)NS(C)(=O)=O)c2n1 CHEMBL4089965 Ki 0.03 nM
COc1cc(COc2ccc(OC)cc2CCCNC(C)=O)cc(OC)c1 CHEMBL1091998 Ki 0.0326 nM
CCCC(=O)NCC1Cc2cccc3ccc(OC)c1c23 CHEMBL130214 Ki 0.034 nM
CC(=O)NCCC1=C(c2cccnc2)Cc2ccc3c(c21)CCO3 CHEMBL1774524 Ki 0.034 nM
CC(C)C1=C(CCNC(=O)C2CC2)c2c(ccc3c2CCO3)C1 CHEMBL1774515 Ki 0.035 nM
COc1ccc(C2=C(CCNC(C)=O)c3c(ccc4c3CCO4)C2)cc1 CHEMBL1774527 Ki 0.037 nM
COc1ccc2[nH]c(-c3ccccc3)c(CCNC(C)=O)c2c1 CHEMBL15060 pKi 0.03802 nM
COc1cc2c([C@@H](C)CNC(C)=O)c[nH]c2cc1Cl CHEMBL4079759 pKi 0.03981 nM
CC(=O)NCCc1cccc2ccc(OCCCCCCCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12 CHEMBL14417 Ki 0.04 nM
CNC(=O)NCCc1c(-c2ccccc2)oc2ccc(OC)cc12 CHEMBL94838 Ki 0.04 nM
CCCC(=O)NC[C@@H]1C[C@H]1c1cccc2c1OC(CCC)N2 CHEMBL19211 Ki 0.04 nM
CCC(=O)NCC[C@@H]1CCc2ccc3c(c21)CCO3 CHEMBL1218 Ki 0.045 nM
COc1ccc2c(c1)c(CCNC(C)=O)c(I)n2C CHEMBL300056 Ki 0.047 nM
COc1ccc(OCc2ccccc2)c(CCCNC(C)=O)c1 CHEMBL1091160 Ki 0.04705 nM
CCC(=O)NCC[C@@H]1CCc2ccc3nc(C)oc3c21 CHEMBL3648359 IC50 0.049 nM
COc1ccc2oc(Cc3ccccc3)c(CCNC(C)=O)c2c1 CHEMBL329263 Ki 0.05 nM
CCCC(=O)NCCc1c2n(c3ccc(OC)cc13)Cc1ccccc1-2 CHEMBL10009 Ki 0.05 nM
CCC(=O)NCCCc1cc(OC)ccc1OCc1cccc(OC)c1 CHEMBL2326199 EC50 0.05 nM
CCOc1nc2ccc3c(c2n1CCNC(C)=O)CCO3 CHEMBL4852440 EC50 0.05 nM
CCC(=O)NCCC1CCc2ccc3nc(C)sc3c21 CHEMBL4868554 Ki 0.058 nM
C=CCC(=O)NCCc1c(Cc2ccccc2)oc2ccc(OC)cc12 CHEMBL97186 Ki 0.06 nM
COc1ccc2c(c1)c(CCNC(C)=O)c1n2Cc2ccccc2-1 CHEMBL9772 Ki 0.06 nM
COc1nc2ccc3c(c2n1CCNC(C)=O)CCO3 CHEMBL4873903 EC50 0.06 nM
COc1ccc2[nH]c(-c3cccnc3)c(CCNC(C)=O)c2c1 CHEMBL5417297 pKi 0.06026 nM
COc1ccc2[nH]c(Sc3ccccc3)c(CCNC(C)=O)c2c1 CHEMBL5407163 pKi 0.0631 nM
COc1cccc(N(CCNC(C)=O)c2ccccc2)c1 CHEMBL235327 Log Ki 0.06607 nM
CCCC(=O)NCC1CCc2c(OC)ccc3cccc1c23 CHEMBL131424 Ki 0.068 nM
CCCC(=O)NCC1CCc2cccc3ccc(OC)c1c23 CHEMBL131252 Ki 0.069 nM
COc1ccc2[nH]cc(CCNC(C)=O)c2c1 CHEMBL45 EC50 0.069 nM
COc1ccc2cccc(CCNC(C)=O)c2c1 CHEMBL10878 pEC50 0.06918 nM
CCC(=O)NC[C@@H]1C[C@H]1c1cccc2nc(CCCCc3ccccc3)oc12 CHEMBL2112690 Ki 0.07 nM
COc1ccc2ccc(OC)c(/C=C/NC(C)=O)c2c1 CHEMBL2314259 Ki 0.07 nM
CNC(=O)NCC1CCc2ccc3ccc(OC)cc3c21 CHEMBL4279639 Ki 0.07 nM
CC(=O)NCC[C@@H]1CCc2ccc3nc(C)oc3c21 CHEMBL3648356 Ki 0.07 nM
CCC(=O)NC[C@@H]1C[C@H]1c1cccc2c1CCO2 CHEMBL2103822 Ki 0.07 nM
CCC(=O)NCCCc1cc(OC)ccc1C#Cc1cccc(OC)c1 CHEMBL2326200 Ki 0.073 nM
CC(=O)NCCC1CCc2ccc3ncoc3c21 CHEMBL3648354 Ki 0.073 nM
CCCC1Nc2cccc([C@@H]3C[C@H]3CNC(=O)CC)c2O1 CHEMBL276921 Ki 0.08 nM
COc1ccc2oc(I)c(CCNC(C)=O)c2n1 CHEMBL3765401 Ki 0.08 nM
CCNC(=O)NCCC1=C(C(C)C)Cc2ccc3c(c21)CCO3 CHEMBL1774517 Ki 0.084 nM
CCC(=O)NCC1Cc2cccc3ccc(OC)c1c23 CHEMBL130542 Ki 0.085 nM
CC(=O)NCCc1c(-c2ccccc2)nn2ccc3c(c12)CCO3 CHEMBL1802022 Ki 0.085 nM
CC(=O)NCCC1CCc2ccc3nc(C)sc3c21 CHEMBL3648362 Ki 0.086 nM
CCC(=O)NCCC1CCc2ccc3nc(C)oc3c21 CHEMBL3648358 Ki 0.088 nM
COc1ccc2ccccc2c1/C=C/NC(C)=O CHEMBL2314257 Ki 0.09 nM
COc1ccc2ccc3occ(CCNC(C)=O)c3c2c1 CHEMBL3759802 Ki 0.09 nM
COc1ccc2oc(-c3ccc4ccccc4c3)c(CCNC(C)=O)c2n1 CHEMBL3764765 Ki 0.09 nM
CNC(=O)NCCc1cccc2ccc(OC)nc12 CHEMBL4084612 Ki 0.09 nM
CCNC(=O)NCCc1cccc2ccc(OC)nc12 CHEMBL4062947 Ki 0.09 nM
CCCC(=O)NCCn1c(OCC)nc2ccc(OC)cc21 CHEMBL4874954 EC50 0.09 nM
CC(=O)NCCC1CCc2ccc3nc(CCCCc4ccccc4)oc3c21 CHEMBL3648361 IC50 0.091 nM
CCCC(=O)NCC1Cc2cccc3cccc1c23 CHEMBL337882 Ki 0.093 nM
COc1ccc2cccc3c2c1C(CNC(C)=O)CC3 CHEMBL132802 Ki 0.094 nM
CCCC(=O)NCC1CCc2c(OC)ccc3ccc(OC)c1c23 CHEMBL340832 Ki 0.1 nM
CCCC(=O)Nc1ccc(N(C)c2cccc(OC)c2)cc1 CHEMBL266549 Ki 0.1 nM
CNC(=S)NCCc1cccc2ccc(OC)nc12 CHEMBL4095210 Ki 0.1 nM
COc1ccc2ccc3c(c2c1)C(C)(CNC(C)=O)CC3 CHEMBL4278248 Ki 0.1 nM
COCC(=O)NCC1CCc2ccc3ccc(OC)cc3c21 CHEMBL4292336 Ki 0.1 nM
COc1ccc2ccc3c(c2c1)C(CNS(C)(=O)=O)CC3 CHEMBL4280601 Ki 0.1 nM
COc1ccc2ccc3c(c2c1)C(CNC(N)=O)CC3 CHEMBL4278575 Ki 0.1 nM
CCNC(=O)NCC1CCc2ccc3ccc(OC)cc3c21 CHEMBL4290302 Ki 0.1 nM
CNC(=S)NCC1CCc2ccc3ccc(OC)cc3c21 CHEMBL4281915 Ki 0.1 nM
CCCC(=O)NCCN(c1ccccc1)c1cccc(OC)c1 CHEMBL279401 Log Ki 0.1047 nM
C=CCC(=O)NCCc1c(Cc2cccc(OC)c2)oc2ccc(OC)cc12 CHEMBL329086 Ki 0.11 nM
COc1cccc(C(CCNC(C)=O)c2ccc3ccccc3c2)c1 CHEMBL457128 Ki 0.11 nM
COc1cccc(N(CCNC(C)=O)c2ccc3ccccc3c2)c1 CHEMBL237234 Log Ki 0.1122 nM
COc1ccc2cccc3c2c1C(CNC(C)=O)C3 CHEMBL130490 Ki 0.12 nM
CCCC(=O)Nc1ccc(Cc2cccc(OC)c2)cc1 CHEMBL7867 Ki 0.12 nM
CCC(=O)NCCc1c2n(c3ccc(OC)cc13)CCc1ccccc1-2 CHEMBL9997 Ki 0.12 nM
CC(=O)NCC[C@@H]1CCc2ccc3nc(C)sc3c21 CHEMBL3648363 IC50 0.12 nM
CC(=O)NCCC1CCc2ccc3nc(Cc4ccccc4)oc3c21 CHEMBL4870108 Ki 0.12 nM
COc1ccc2c(c1)c(CCNC(C)=O)c(-c1cccc3ccccc13)n2C CHEMBL5397024 pKi 0.1259 nM
CCCC1Nc2cccc([C@@H]3C[C@H]3CNC(C)=O)c2O1 CHEMBL19128 Ki 0.13 nM
CCC(=O)NCC1CCc2c(OC)ccc3cccc1c23 CHEMBL129889 Ki 0.13 nM
CC(=O)NCCC1CCc2ccc3nc(C)oc3c21 CHEMBL3648355 Ki 0.13 nM
CCCC1Nc2cccc([C@@H]3C[C@H]3CNC(=O)C3CC3)c2O1 CHEMBL279343 Ki 0.14 nM
CCC(=O)NCCc1c(C2CC2)nn2ccc3c(c12)CCO3 CHEMBL1802028 Ki 0.14 nM
Cc1nc2ccc3c(c2o1)C(CCNC(=O)C(F)(F)F)CC3 CHEMBL3648369 IC50 0.14 nM
COc1ccc2oc(-c3ccccc3)c(CCNC(C)=O)c2n1 CHEMBL3765540 Ki 0.14 nM
COc1ccc2ccc(OC)c3c2c1CCC3CNC(C)=O CHEMBL336509 Ki 0.145 nM
COc1ccc2[nH]c(I)c(CCNC(C)=O)c2c1 CHEMBL289233 Ki 0.15 nM
CC(=O)NCCC1CCc2ccc3nc(C4CC4)oc3c21 CHEMBL3648366 Ki 0.15 nM
COc1nc2ccc3c(c2o1)C(CCNC(C)=O)CC3 CHEMBL3648367 Ki 0.15 nM
CCC(=O)NCC1CCc2c(OC)ccc3ccc(OC)c1c23 CHEMBL336054 Ki 0.153 nM
CCCC(=O)NCCc1c2n(c3ccc(OCC)cc13)Cc1ccccc1-2 CHEMBL9590 Ki 0.16 nM
CCC(=O)NCC1Cc2ccccc2Cc2ccc(OC)cc21 CHEMBL189414 Ki 0.16 nM
CCc1nc2ccc3c(c2o1)C(CCNC(C)=O)CC3 CHEMBL3648365 Ki 0.16 nM
CCC(=O)Nc1ccc(N(C)c2cccc(OC)c2)cc1 CHEMBL7832 Ki 0.17 nM
CCC(=O)NCCc1c2n(c3ccc(OC)cc13)Cc1ccccc1-2 CHEMBL274317 Ki 0.17 nM
COc1cc2c(CCNC(C)=O)c(I)[nH]c2cc1[N+](=O)[O-] CHEMBL52755 Ki 0.17 nM
CC(=O)NCCc1cccc2ccc(OCCCCCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12 CHEMBL14136 Ki 0.18 nM
CCCC(=O)NCC1CCc2cccc3cccc1c23 CHEMBL338425 Ki 0.18 nM
CCc1nc2cccc([C@@H]3C[C@H]3CNC(=O)C3CC3)c2o1 CHEMBL2112724 Ki 0.19 nM
CCCC(=O)NCCC1CCc2c(OC)ccc3ccc(OC)c1c23 CHEMBL129890 Ki 0.19 nM
CCCC(=O)Nc1ccc(Sc2cccc(OC)c2)cc1 CHEMBL7771 Ki 0.19 nM
CCC(=O)NCCc1c(C)nn2ccc3c(c12)CCO3 CHEMBL1802024 Ki 0.19 nM
CC(=O)NCCc1c[nH]c2ccc(OCCc3ccccc3)cc12 CHEMBL4467954 Ki 0.19 nM
CCOc1nc2ccc(OC)cc2n1CCNC(=O)CC CHEMBL4872217 EC50 0.19 nM
COc1ccc2[nH]c(-c3cccc4ccccc34)c(CCNC(C)=O)c2c1 CHEMBL5435438 pKi 0.1905 nM
CC(=O)NCCN(c1ccccc1)c1cccc(Br)c1 CHEMBL235328 Log Ki 0.1995 nM
CCCC(=O)NCCc1c(Cc2ccccc2)oc2ccc(OC)cc12 CHEMBL96859 Ki 0.2 nM
CCCC(=O)NCCc1c2n(c3ccc(OC)cc13)CCc1ccccc1-2 CHEMBL10099 Ki 0.2 nM
COc1ccc2[nH]c(-c3ccccc3)c(CCNC(C)=O)c2n1 CHEMBL1823015 Ki 0.2 nM
COc1ccc2ccc(OC)c([C@@H]3C[C@H]3NC(C)=O)c2c1 CHEMBL2314253 Ki 0.2 nM
CCC(=O)NCCCc1cc(OC)ccc1-c1cccc(OC)c1 CHEMBL2326203 EC50 0.2 nM
COc1cc2c(CCNC(C)=O)c[nH]c2cc1Cl CHEMBL34730 Ki 0.2 nM
COc1ccc2cccc(CCNC(C)=O)c2n1 CHEMBL4102177 Ki 0.2 nM
COc1ccc2cccc(CCNC(N)=O)c2n1 CHEMBL4071572 Ki 0.2 nM
COc1ccc2ccc3c(c2c1)C(CNC(C)=O)CC3 CHEMBL4293386 Ki 0.2 nM
COc1ccc2ccc3c(c2n1)C(CNC(C)=O)CC3 CHEMBL4281712 Ki 0.2 nM
COc1ccc2ccc3c(c2c1)C(C)(CNS(C)(=O)=O)CC3 CHEMBL4288497 Ki 0.2 nM
CCCNC(=O)NCC1CCc2ccc3ccc(OC)cc3c21 CHEMBL4294790 Ki 0.2 nM
CCCNC(=O)NCC1(C)CCc2ccc3ccc(OC)cc3c21 CHEMBL4291381 Ki 0.2 nM
CNC(=O)NCC1CCc2ccc3ccc(OC)nc3c21 CHEMBL4283539 Ki 0.2 nM
CNC(=S)NCC1(C)CCc2ccc3ccc(OC)cc3c21 CHEMBL4280791 Ki 0.2 nM
C/C=C/C(=O)NCCc1c(-c2ccccc2)oc2ccc(OC)cc12 CHEMBL96104 Ki 0.21 nM
CCOc1ccc2c(c1)c(CCNC(C)=O)c1n2Cc2ccccc2-1 CHEMBL274896 Ki 0.21 nM
CC(=O)NCCc1c(-c2cccc(O)c2)oc2ccc3c(c12)CCCO3 CHEMBL3103594 Ki 0.21 nM
COc1cccc(/C(=C/CNC(C)=O)c2ccccc2)c1 CHEMBL218708 Log Ki 0.2188 nM
COc1ccc2oc(Cc3cccc(Cl)c3)c(CCNC(C)=O)c2c1 CHEMBL94607 Ki 0.22 nM
CCC(=O)NCC1Cc2cccc3cccc1c23 CHEMBL133001 Ki 0.22 nM
CC(=O)NCC1CCc2cccc3cccc1c23 CHEMBL130319 Ki 0.22 nM
CCC(=O)NCCc1c(CC)nn2ccc3c(c12)CCO3 CHEMBL1802026 Ki 0.22 nM
CC(=O)NC/C=C1\CCc2ccc3nc(C)sc3c21 CHEMBL4115681 IC50 0.22 nM
CCC(=O)NC/C=C1\CCc2ccc3nc(C)oc3c21 CHEMBL4114700 IC50 0.22 nM
CCC(=O)NC[C@@H]1CCc2ccccc2[C@@H]1c1ccccc1 CHEMBL4083618 Ki 0.22 nM
COc1ccc2oc(Cc3cccc(F)c3)c(CCNC(C)=O)c2c1 CHEMBL95166 Ki 0.23 nM
COc1cccc(N(C)c2ccc(NC(C)=O)cc2)c1 CHEMBL8168 Ki 0.23 nM
CCC(=O)NC[C@@H]1CCc2ccccc2[C@H]1c1ccccc1 CHEMBL4061850 Ki 0.23 nM
CC(=O)NCCC1CCc2ccc3nc(-c4ccccc4)oc3c21 CHEMBL4864102 Ki 0.23 nM
CCCC(=O)NC[C@@H]1C[C@H]1c1cccc2c1OC(CCCCc1ccccc1)N2 CHEMBL19026 Ki 0.24 nM
CCC(=O)NCCC1Cc2cccc3ccc(OC)c1c23 CHEMBL336858 Ki 0.24 nM
C=CCC(=O)NCCc1c(Sc2ccc(F)cc2)sc2ccc(F)cc12 CHEMBL1779810 Ki 0.24 nM
CCC(=O)NCCCc1cc(OC)ccc1Cc1cccc(OC)c1 CHEMBL2326202 EC50 0.24 nM
CC(=O)NCCC1=CCc2ccc3nc(C)oc3c21 CHEMBL3648350 IC50 0.24 nM
CCCC(=O)NCC1Cc2ccccc2Cc2ccc(OC)cc21 CHEMBL189395 Log Ki 0.2455 nM
COc1cccc(Cc2oc3ccc(OC)cc3c2CCNC(C)=O)c1 CHEMBL33549 Ki 0.25 nM
COc1ccc2[nH]c(Cc3ccccc3)c(CCNC(C)=O)c2c1 CHEMBL339105 Ki 0.25 nM
COc1ccc2ccc(OC)c3c2c1CCC3CNC(=O)C1CC1 CHEMBL133416 Ki 0.26 nM
CCOc1ccc2c(c1)c(CCNC(=O)CC)c1n2Cc2ccccc2-1 CHEMBL9630 Ki 0.26 nM
CCOc1nc2ccc(OC)cc2n1CCNC(C)=O CHEMBL4859677 EC50 0.26 nM
COc1ccc2c(c1)c(C(C)CNC(C)=O)cn2C CHEMBL210791 Ki 0.27 nM
COc1ccc2cc(-c3cccc(N)c3)cc(CCNC(C)=O)c2c1 CHEMBL490188 Ki 0.27 nM
CCOc1nc2cc(Cl)c(OC)cc2n1CCNC(C)=O CHEMBL4852096 EC50 0.27 nM
COc1cccc(C(=CCNC(C)=O)c2cccc(OC)c2)c1 CHEMBL218225 Log Ki 0.2754 nM
CCCC1Nc2cccc([C@@H]3C[C@H]3CNC(=O)C(C)C)c2O1 CHEMBL19050 Ki 0.28 nM
CCCC(=O)NCCc1cc(-c2cccc(CO)c2)cc2ccc(OC)cc12 CHEMBL476341 Ki 0.28 nM
CCC(=O)NCCn1ccc2ccc(OC)nc21 CHEMBL1760946 Ki 0.28 nM
CC(=O)NCCc1c(C2CC2)nn2ccc3c(c12)CCO3 CHEMBL1802027 Ki 0.28 nM
CCOC(=O)c1[nH]c2ccc(OC)c3c2c1[C@@H](CNC(C)=O)CC3 CHEMBL3260982 Ki 0.29 nM
COc1ccc2[nH]c(-c3cccc4[nH]ccc34)c(CCNC(C)=O)c2c1 CHEMBL5418672 pKi 0.2951 nM
COc1ccc2[nH]cc(CCNC(C)=O)c2n1 CHEMBL1760944 Ki 0.3 nM
CCCC(=O)NCCn1ccc2ccc(OC)nc21 CHEMBL1760947 Ki 0.3 nM
CNC(=O)N/C=C/c1c(OC)ccc2ccc(OC)cc12 CHEMBL2314260 Ki 0.3 nM
CNC(=O)CCc1cccc2ccc(OC)nc12 CHEMBL4079784 Ki 0.3 nM
COc1ccc2cccc(CCC(=O)NCCF)c2n1 CHEMBL4061905 Ki 0.3 nM
COC(=O)NCCc1cccc2ccc(OC)nc12 CHEMBL4082097 Ki 0.3 nM
CC(=O)NCC1Cc2ccccc2N(c2ccccc2)C1 CHEMBL4074273 Ki 0.3 nM
CCNC(=O)NCC1(C)CCc2ccc3ccc(OC)cc3c21 CHEMBL4286896 Ki 0.3 nM
CCCNC(=S)NCC1(C)CCc2ccc3ccc(OC)cc3c21 CHEMBL4284223 Ki 0.3 nM
CCOc1nc2cc(Cl)c(OC)cc2n1CCCNC(C)=O CHEMBL4846505 EC50 0.3 nM
CCCC(=O)N[C@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL136531 Ki 0.31 nM
COc1ccc2cccc3c2c1C(CNC(=O)C1CC1)C3 CHEMBL334962 Ki 0.31 nM
CCC(=O)NC[C@H](CO)c1cccc2ccc(OC)cc12 CHEMBL4074895 pKi 0.3162 nM
CCC(=O)NC[C@@H]1C[C@H]1c1cccc2c1OC(C(C)C)N2 CHEMBL428692 Ki 0.32 nM
CCCC(=O)NC[C@@H]1C[C@H]1c1cccc2nc(CC)oc12 CHEMBL2112722 Ki 0.33 nM
CCC(=O)NCCc1c(C(F)(F)F)nn2ccc3c(c12)CCO3 CHEMBL1802030 Ki 0.33 nM
COc1ccc2occ(CCNC(C)=O)c2c1 CHEMBL323332 Ki 0.34 nM
COc1ccc2oc(Cc3ccccc3OC)c(CCNC(C)=O)c2c1 CHEMBL329960 Ki 0.34 nM
CCCC(=O)NCCC1Cc2cccc3ccc(OC)c1c23 CHEMBL434226 Ki 0.34 nM
CC(=O)NCCC1=C(c2ccccc2OC(C)C)Cc2ccc3c(c21)CCO3 CHEMBL1774528 Ki 0.34 nM
COc1ccc2cccc(C(CO)CNC(=O)C(F)F)c2c1 CHEMBL4104020 pKi 0.3467 nM
CNC(=O)NCCc1c(Cc2ccccc2)oc2ccc(OC)cc12 CHEMBL94301 Ki 0.35 nM
CCOc1nc2ccc(OC)cc2n1CCCNC(C)=O CHEMBL4848885 EC50 0.35 nM
CCC(=O)NCCC1CCc2ccc3nn(C)cc3c21 CHEMBL4869029 Ki 0.35 nM
CCCC(=O)NCCc1c[nH]c2c(Br)cc(OC)cc12 CHEMBL233308 Log Ki 0.3548 nM
COc1ccc2cc(-c3cccc(CO)c3)cc(CCNC(C)=O)c2c1 CHEMBL476131 Ki 0.36 nM
CC(=O)NC[C@@H]1C[C@H]1c1cccc2nc(CCCCc3ccccc3)oc12 CHEMBL2112700 Ki 0.37 nM
COc1ccc2cc(-c3ccccc3)cc(CCNC(C)=O)c2c1 CHEMBL453138 Ki 0.37 nM
CC(=O)NC/C=C1\CCc2ccc3nc(C)oc3c21 CHEMBL4114658 IC50 0.37 nM
CCC(=O)NCCc1c(OC)ccc2ccc(OC)cc12 CHEMBL291857 Ki 0.38 nM
COc1cccc(/C(=C/CNC(=O)C2CCC2)c2ccccc2)c1 CHEMBL218065 pA2 0.389 nM
COc1ccc2cccc3c2c1C(CCNC(C)=O)CC3 CHEMBL132340 Ki 0.39 nM
CCCC(=O)Nc1ccc(Nc2cccc(OC)c2)cc1 CHEMBL7229 Ki 0.39 nM
CCC(=O)N[C@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL343825 Ki 0.4 nM
COc1ccc2ccc3oc(CNC(C)=O)cc3c2c1 CHEMBL3758717 Ki 0.4 nM
CCNC(=S)NCCc1cccc2ccc(OC)nc12 CHEMBL4079699 Ki 0.4 nM
COC(=O)NCC1CCc2ccc3ccc(OC)cc3c21 CHEMBL4285145 Ki 0.4 nM
CCS(=O)(=O)NCC1CCc2ccc3ccc(OC)cc3c21 CHEMBL4286494 Ki 0.4 nM
CCCNC(=O)NCC1CCc2ccc3ccc(OC)nc3c21 CHEMBL4278446 Ki 0.4 nM
COc1ccc2ccc3c(c2c1)C(CNC(N)=S)CC3 CHEMBL4289115 Ki 0.4 nM
COc1ccc2oc(Cc3ccccc3)c(CCNC(=O)CI)c2c1 CHEMBL328617 Ki 0.41 nM
CCCC(=O)NCCc1ccnc2ccc(OC)cc12 CHEMBL68864 Ki 0.41 nM
COc1ccc2cccc3c2c1CCC3CNC(C)=O CHEMBL336647 Ki 0.41 nM
COc1ccc2c(c1)c(CCNC(C)=O)cn2Cc1cc(OC)c(OC)cc1[N+](=O)[O-] CHEMBL5174929 pEC50 0.4169 nM
COc1ccc(Cc2oc3ccc(OC)cc3c2CCNC(C)=O)cc1 CHEMBL317742 KB 0.42 nM
CCNC(=O)N[C@@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL136564 Ki 0.42 nM
COc1ccc2cc(-c3cccc(C=O)c3)cc(CCNC(C)=O)c2c1 CHEMBL491604 Ki 0.42 nM
CCc1nn2ccc3c(c2c1CCNC(C)=O)CCO3 CHEMBL1802025 Ki 0.42 nM
CC(=O)NC/C=C1\CCc2ccc3nc(CCCCc4ccccc4)oc3c21 CHEMBL4114715 IC50 0.43 nM
CCC(=O)NC[C@@H]1C[C@H]1c1cccc2nc(CC)oc12 CHEMBL2112727 Ki 0.44 nM
C=CCNC(=O)CCc1c[nH]c2ccc(OC)cc12 CHEMBL3580910 Ki 0.45 nM
CCCC(=O)NCC(C)c1cn(C)c2ccc(OC)cc12 CHEMBL377101 Ki 0.47 nM
O=C(NC[C@@H]1C[C@H]1c1cccc2nc(CCCCc3ccccc3)oc12)C1CC1 CHEMBL2112734 Ki 0.48 nM
CCC(=O)NC[C@@H]1CN(C)c2ccccc2[C@@H]1c1ccccc1 CHEMBL4068887 Ki 0.48 nM
CCCC(=O)Nc1ccc(N(C)c2cccc3c2CCO3)cc1 CHEMBL7807 Ki 0.49 nM
CCCC(=O)NCCc1c2n(c3ccc(OC)cc13)CCCc1ccccc1-2 CHEMBL274438 Ki 0.5 nM
CNc1cccc(-c2cc(CCNC(C)=O)c3cc(OC)ccc3c2)c1 CHEMBL477835 EC50 0.5 nM
COc1ccc2cccc(CCC(=O)NC3CC3)c2n1 CHEMBL4070527 Ki 0.5 nM
CC(=O)NCC1Cc2cccc3cccc1c23 CHEMBL131602 Ki 0.51 nM
COc1ccc2c(c1)c(CCNC(C)=O)c1n2CCc2ccccc2-1 CHEMBL274842 Ki 0.51 nM
CCC(=O)NCCc1cc(-c2cccc(CO)c2)cc2ccc(OC)cc12 CHEMBL518113 Ki 0.52 nM
COc1ccc2nc(OC)n(CCNC(C)=O)c2c1 CHEMBL4854625 EC50 0.52 nM
CC(=O)NCCc1c(C)nn2ccc3c(c12)CCO3 CHEMBL1802023 Ki 0.53 nM
CCC(=O)NCCc1c[nH]c2c(Br)cc(OC)cc12 CHEMBL233729 Log Ki 0.537 nM
COc1ccc2cccc(C(CO)CNC(=O)CF)c2c1 CHEMBL4095334 pKi 0.537 nM
CCC(=O)NCCC1CCc2c(OC)ccc3ccc(OC)c1c23 CHEMBL337024 Ki 0.55 nM
COc1ccc2ccc(OC)c3c2c1CCC3CCNC(C)=O CHEMBL130898 Ki 0.55 nM
COc1ccc2cc(-c3cccc(CBr)c3)cc(CCNC(C)=O)c2c1 CHEMBL490595 Ki 0.56 nM
CCOc1nc2ccc(OC)cc2n1CCNC(=O)C1CC1 CHEMBL4869463 EC50 0.56 nM
O=C(NCC1Cc2cccc3cccc1c23)C1CC1 CHEMBL341439 Ki 0.57 nM
COc1ccc2cccc3c2c1C(CCNC(C)=O)C3 CHEMBL130203 Ki 0.59 nM
COc1ccc2ccn(CCNC(C)=O)c2n1 CHEMBL1760945 Ki 0.6 nM
COc1ccc2ccc3oc(CNC(=O)C4CC4)cc3c2c1 CHEMBL3758679 Ki 0.6 nM
COC(=O)c1cccc(-c2cc(CCNC(C)=O)c3cc(OC)ccc3c2)c1 CHEMBL491605 Ki 0.64 nM
CC(=O)NCCc1c(Sc2ccc(F)cc2)sc2ccc(F)cc12 CHEMBL1779804 EC50 0.64 nM
COc1cccc(N(C)CCNC(C)=O)c1 CHEMBL237236 Log Ki 0.6457 nM
CCN(CC)c1ccc2c(COC(=O)n3cc(CCNC(C)=O)c4cc(OC)ccc43)cc(=O)oc2c1 CHEMBL5209359 pEC50 0.6457 nM
COc1ccc2c(c1)C(CNC(C)=O)Cc1ccccc1C2 CHEMBL189449 Log Ki 0.6607 nM
CCC(=O)NCCc1c(Sc2ccc(F)cc2)sc2ccc(F)cc12 CHEMBL1779805 Kb 0.67 nM
CCCC(=O)NCCc1c[nH]c2c(C)cc(OC)cc12 CHEMBL391350 Log Ki 0.6761 nM
COc1cc(Br)c2[nH]cc(CCNC(C)=O)c2c1 CHEMBL233728 Log Ki 0.6761 nM
CCCC(=O)Nc1ccc(Oc2cccc3c2CCO3)cc1 CHEMBL7700 Ki 0.68 nM
COc1ccc2c3c(n(CCNC(C)=O)c2n1)CCCC3 CHEMBL1760957 Ki 0.68 nM
CC(=O)NCCc1csc2ccc(F)cc12 CHEMBL1779803 EC50 0.68 nM
C=CC(=O)NCCc1c(Cc2ccccc2)oc2ccc(OC)cc12 CHEMBL96548 Ki 0.69 nM
COc1ccc2cccc([C@@H]3C[C@H]3NC(C)=O)c2c1 CHEMBL2314251 Ki 0.7 nM
COc1ccc2ccc3occ(CNC(C)=O)c3c2c1 CHEMBL3758225 Ki 0.7 nM
COc1ccc2ccc3oc(CNC(=O)CF)cc3c2c1 CHEMBL3759084 Ki 0.7 nM
CCCC(=O)Nc1ccc(Cc2cccc3c2CCO3)cc1 CHEMBL8169 Ki 0.71 nM
COc1ccc2cc(-c3cccc(CI)c3)cc(CCNC(C)=O)c2c1 CHEMBL477833 Ki 0.71 nM
CCCC(=O)NCC(C)(C)c1cn(C)c2ccc(OC)cc12 CHEMBL207745 Ki 0.74 nM
CCC1Nc2cccc([C@@H]3C[C@H]3CNC(=O)C(C)C)c2O1 CHEMBL431103 Ki 0.75 nM
CCCCC(=O)Nc1ccc(Oc2cccc(OC)c2)cc1 CHEMBL7650 Ki 0.75 nM
CCCC(=O)Nc1ccc(Oc2cccc(OC)c2)cc1 CHEMBL7599 Ki 0.75 nM
CC(=O)NCCC1CCc2ccc3nn(C)cc3c21 CHEMBL4872592 Ki 0.75 nM
COc1cccc(CCCNC(C)=O)c1 CHEMBL50398 Ki 0.751 nM
COc1cccc(N(CCNC(C)=O)Cc2ccccc2)c1 CHEMBL395437 Log Ki 0.7586 nM
COc1ccc2nc(SC)n(CCNC(C)=O)c2c1 CHEMBL4867553 EC50 0.76 nM
COc1cc2c(CCNC(C)=O)c(I)n(C)c2cc1[N+](=O)[O-] CHEMBL55084 Ki 0.77 nM
CC(=O)NCCC1=C(c2ccc(C(C)(C)C)cc2)Cc2ccc3c(c21)CCO3 CHEMBL1774530 Ki 0.77 nM
Cc1nc2ccc3c(c2o1)C(CCNC(=O)C1CC1)CC3 CHEMBL3648368 IC50 0.77 nM
CCCC(=O)Nc1ccc(Cc2cccc3occc23)cc1 CHEMBL7875 Ki 0.78 nM
COc1ccc2cccc3c2c1CCC3CNC(=O)C1CC1 CHEMBL130876 Ki 0.79 nM
COc1ccc2cccc([C@@H](CO)CNC(=O)CF)c2c1 CHEMBL4087633 pEC50 0.7943 nM
CCCC(=O)NC[C@@H]1C[C@H]1c1cccc2c1OC(C(C)C)N2 CHEMBL553105 Ki 0.8 nM
COCc1cccc(-c2cc(CCNC(C)=O)c3cc(OC)ccc3c2)c1 CHEMBL491403 Kb 0.8 nM
COc1ccc2[nH]cc(C3CCCN(C(C)=O)C3)c2c1 CHEMBL3260983 Ki 0.8 nM
CNC(=S)NCc1cc2c(ccc3ccc(OC)cc32)o1 CHEMBL3759372 Ki 0.8 nM
COc1ccc2ccc3c(c2n1)C(CCNC(C)=O)CC3 CHEMBL4277185 Ki 0.8 nM
COc1cc2c(cc1Cl)nc(OC)n2CCNC(C)=O CHEMBL4859295 Ki 0.8 nM
COc1ccc2cccc(CCNC(=O)C(F)F)c2c1 CHEMBL1946221 Ki 0.85 nM
CCCC(=O)NCC1(c2cn(C)c3ccc(OC)cc23)CCC1 CHEMBL207625 Ki 0.86 nM
COc1ccc(N(CCNC(C)=O)c2cccc(OC)c2)cc1 CHEMBL394430 Log Ki 0.871 nM
CCC1Nc2cccc([C@@H]3C[C@H]3CNC(C)=O)c2O1 CHEMBL18960 Ki 0.88 nM
COc1ccc2c(c1)C(CNC(C)=O)Cc1ccccc1C2=O CHEMBL427516 Log Ki 0.8913 nM
COc1ccc2c(c1)[C@@H](CCNC(=O)C1CCC1)C[C@@H](c1ccccc1)C2 CHEMBL514280 Ki 0.9 nM
CC(=O)NCCc1c(C(F)(F)F)nn2ccc3c(c12)CCO3 CHEMBL1802029 Ki 0.93 nM
CNC(=O)N[C@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL138012 Ki 0.94 nM
COc1ccc2cc(-c3cccc(N(C)C)c3)cc(CCNC(C)=O)c2c1 CHEMBL478217 Ki 0.94 nM
COc1ccc2c(c1)c(CCNC(=O)C1CC1)c1n2Cc2ccccc2-1 CHEMBL10110 Ki 0.95 nM
CCC(=O)NCCC1CCc2ccn3nc(C)cc3c21 CHEMBL4874630 Ki 0.95 nM
CSc1ccc2cccc(CCNC(C)=O)c2c1 CHEMBL456727 IC50 0.955 nM
CCC(=O)NCCc1ccnc2ccc(OC)cc12 CHEMBL306468 Ki 0.96 nM
CCCC(=O)NCCCc1cccc2nc(CC)oc12 CHEMBL124422 Ki 1.0 nM
CCC(=O)NCCCc1cccc2nc(CC)oc12 CHEMBL124362 Ki 1.0 nM
CC(=O)N[C@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL336268 Ki 1.0 nM
CCCC1Nc2cccc([C@@H]3C[C@H]3CNC(=O)NCC)c2O1 CHEMBL19109 Ki 1.0 nM
C#CCNC(=O)CCc1c[nH]c2ccc(OC)cc12 CHEMBL3580908 Ki 1.0 nM
CCS(=O)(=O)NC(=O)CCc1cccc2ccc(OC)nc12 CHEMBL4100108 Ki 1.0 nM
CCN1CC(CNC(C)=O)Cc2ccccc21 CHEMBL4064626 Ki 1.0 nM
CC(=O)NCC1Cc2ccccc2N(Cc2ccccc2)C1 CHEMBL4084568 Ki 1.0 nM
CCC(=O)NC1Cc2ccccc2N(c2ccccc2)C1 CHEMBL4064813 EC50 1.0 nM
CCC(=O)NCC(C)c1cn(C)c2ccc(OC)cc12 CHEMBL379616 Ki 1.02 nM
CCC(=O)NCCc1c[nH]c2c(C)cc(OC)cc12 CHEMBL395221 Log Ki 1.096 nM
COc1ccc2[nH]c(-c3ccc4ccccc4c3)c(CCNC(C)=O)c2c1 CHEMBL5394712 pKi 1.096 nM
COc1ccc2[nH]c(CN3CCc4ccccc43)c(CCNC(C)=O)c2c1 CHEMBL514415 Ki 1.1 nM
CC(=O)NCCC1CCc2ccc3nc(CO)oc3c21 CHEMBL4848381 Ki 1.1 nM
CCC(=O)NCC(C)(C)c1cn(C)c2ccc(OC)cc12 CHEMBL426127 Ki 1.15 nM
COc1ccc2oc(Cc3cccc(C(F)(F)F)c3)c(CCNC(C)=O)c2c1 CHEMBL314947 Ki 1.17 nM
CCC(=O)NCCc1c(O)ccc2ccc(OC)cc12 CHEMBL440692 Ki 1.2 nM
CCOc1ccc2ccc(OC)cc2c1CCNC(=O)CC CHEMBL80736 Ki 1.2 nM
CC(=O)NC[C@@H]1C[C@H]1c1cccc2c1OC(C(C)C)N2 CHEMBL278922 Ki 1.2 nM
COc1ccc2occ(CCNC(C)=O)c2n1 CHEMBL3763281 Ki 1.2 nM
COc1ccc2c(c1)c(CCNC(C)=O)cn2C(=O)OCc1ccccc1[N+](=O)[O-] CHEMBL5173623 pEC50 1.288 nM
COc1ccc2c(c1)c(C(C)(C)CNC(C)=O)cn2C CHEMBL208307 Ki 1.29 nM
CCC(=O)NCCc1c(OCCO)ccc2ccc(OC)cc12 CHEMBL78751 Ki 1.3 nM
COc1ccc2oc(-c3cccc4ccccc34)c(CCNC(C)=O)c2n1 CHEMBL3764879 Ki 1.3 nM
COc1cc(Br)c2c(c1)c(CCNC(C)=O)cn2C CHEMBL233309 Log Ki 1.318 nM
CCCC(=O)NCCc1cn(C)c2c(C)cc(OC)cc12 CHEMBL392422 Log Ki 1.349 nM
COc1ccc2nccc(CCNC(C)=O)c2c1 CHEMBL69521 Ki 1.4 nM
CC(=O)N/C=C/c1cccc2ccccc12 CHEMBL229015 Ki 1.4 nM
CC(=O)NCCC1CCc2ccn3nc(C)cc3c21 CHEMBL4874010 Ki 1.4 nM
CCC(=O)NCCc1c2n(c3ccc(OC)cc13)CCCc1ccccc1-2 CHEMBL10293 Ki 1.41 nM
COc1ccc2c(c1)[C@H](N1CCN(C(=O)C(C)C)CC1)CC2 CHEMBL19374 IC50 1.5 nM
COc1ccc2c(c1)C(N1CCN(C(=O)C(C)C)CC1)CC2 CHEMBL18808 IC50 1.5 nM
COc1ccc2oc(CCCc3ccccc3)c(CCNC(C)=O)c2c1 CHEMBL98074 Ki 1.52 nM
COc1cccc(/C(=C\CNC(=O)C2CCC2)c2ccccc2)c1 CHEMBL218709 Log Ki 1.549 nM
COc1cc(C)c2c(c1)c(CCNC(C)=O)cn2C CHEMBL392421 Log Ki 1.549 nM
COc1ccc2ccc(OC)c3c2c1CCC3CCNC(=O)C1CC1 CHEMBL131575 Ki 1.59 nM
CCOc1ccc(OC)cc1CCCNC(C)=O CHEMBL1091561 Ki 1.59 nM
CCC(=O)NCCc1c(OC(=O)CCl)ccc2ccc(OC)cc12 CHEMBL131919 Ki 1.6 nM
COc1ccc2c(c1)[C@H](N1CCN(C(=O)C3CC3)CC1)CC2 CHEMBL19653 IC50 1.6 nM
COc1ccc(OCc2ccccn2)c(CCCNC(C)=O)c1 CHEMBL1091716 Ki 1.61 nM
CCC(=O)NCCc1cc2c(OC)cccc2n1-c1ccccc1 CHEMBL100104 Log Ki 1.66 nM
CC(=O)NCCc1c(Br)[nH]c2ccc(OCCCCCCNC(=O)Oc3cccc(-c4ccccc4)c3)cc12 CHEMBL4210086 pKi 1.698 nM
COc1ccc2oc(-c3ccccc3)c(CCNC(=O)c3ccco3)c2c1 CHEMBL96420 Ki 1.7 nM
CCNC(=O)N1CCN([C@@H]2CCc3ccc(OC)cc32)CC1 CHEMBL280142 IC50 1.7 nM
COc1ccc2ccc3oc(CCNC(C)=O)cc3c2c1 CHEMBL3758720 Ki 1.7 nM
COc1ccc2c(c1)c(CCNC(C)=O)cn2C CHEMBL33700 Log Ki 1.738 nM
COc1cc(C)c2[nH]cc(CCNC(C)=O)c2c1 CHEMBL231872 Log Ki 1.738 nM
CC(=O)NCCc1cccc2ccc(OCCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12 CHEMBL273787 Ki 1.74 nM
COc1ccc2cccc(CCNC(=O)C(F)(F)F)c2c1 CHEMBL322339 pKi 1.778 nM
COc1ccc2cccc(CCNC(=O)C(Cl)Cl)c2c1 CHEMBL3742090 pKi 1.778 nM
CCC(=O)NCCCc1cccc2ncoc12 CHEMBL124476 Ki 1.8 nM
CCC(=O)Nc1ccc(Nc2cccc(OC)c2)cc1 CHEMBL7215 Ki 1.8 nM
COC(=O)Cc1cccc2ccc(OCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12 CHEMBL1095196 Ki 1.84 nM
CCCC(=O)NCCC1Cc2cccc3cccc1c23 CHEMBL133426 Ki 1.86 nM
CCC(=O)NCCC1Cc2cccc3cccc1c23 CHEMBL336333 Ki 1.86 nM
COc1ccc2cc(-c3ccccc3CO)cc(CCNC(C)=O)c2c1 CHEMBL517502 Ki 1.86 nM
CC(C)C(=O)NC[C@@H]1C[C@H]1c1cccc2c1OC(CCCCc1ccccc1)N2 CHEMBL18845 Ki 1.9 nM
COc1cccc(N(C)CCCNC(C)=O)c1 CHEMBL235329 Log Ki 1.995 nM
CC(=O)NC[C@@H]1C[C@H]1c1cccc2c1C[C@@H](CCCCc1ccccc1)O2 CHEMBL359921 Ki 2.0 nM
CCC(=O)NC[C@@H]1C[C@H]1c1cccc2c1C[C@@H](CCCCc1ccccc1)O2 CHEMBL367797 Ki 2.0 nM
CCCC(=O)NC[C@@H]1C[C@H]1c1cccc2c1C[C@@H](CCCCc1ccccc1)O2 CHEMBL367604 Ki 2.0 nM
COc1ccc2ccc3c(c2c1)C(CCNC(C)=O)CC3 CHEMBL4288925 Ki 2.0 nM
CCNC(=S)NCC1CCc2ccc3ccc(OC)cc3c21 CHEMBL4277390 Ki 2.0 nM
CCNC(=S)NCC1(C)CCc2ccc3ccc(OC)cc3c21 CHEMBL4292109 EC50 2.0 nM
COc1ccc2nc(OC)n(CCCNC(C)=O)c2c1 CHEMBL4854836 EC50 2.01 nM
CCNC(=O)N[C@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL136431 Ki 2.1 nM
C/C=C/C(=O)Nc1ccc(Oc2cccc(OC)c2)cc1 CHEMBL7559 Ki 2.1 nM
COc1ccc2ccc3occ(CNC(=O)CF)c3c2c1 CHEMBL3759160 Ki 2.1 nM
CCCOc1ccc(OC)cc1CCCNC(C)=O CHEMBL1091894 Ki 2.12 nM
CCCC(=O)NCCc1cn(C)c2c(Br)cc(OC)cc12 CHEMBL394406 Log Ki 2.138 nM
CCCC(=O)NCCCc1cccc2nc(C)oc12 CHEMBL338659 Ki 2.2 nM
CC(C)C1Nc2cccc([C@@H]3C[C@H]3CNC(=O)C3CC3)c2O1 CHEMBL18846 Ki 2.2 nM
CCNC(=O)NC[C@@H]1C[C@H]1c1cccc2c1OC(CC)N2 CHEMBL19260 Ki 2.2 nM
COc1cc2c(CCNC(C)=O)c(C)[nH]c2cc1Cl CHEMBL3260979 Ki 2.2 nM
COc1ccc2[nH]c(CN3Cc4ccccc4C3)c(CCNC(C)=O)c2c1 CHEMBL3219326 pKi 2.239 nM
CCC(=O)NCCc1cn(C)c2c(Br)cc(OC)cc12 CHEMBL233310 Log Ki 2.291 nM
COc1ccc2[nH]c(CN(C)c3ccccc3)c(CCNC(C)=O)c2c1 CHEMBL560865 pKi 2.291 nM
CCc1nc2cccc(CCCNC(C)=O)c2o1 CHEMBL125665 Ki 2.3 nM
Cc1nc2cccc(CCCNC(=O)C(C)C)c2o1 CHEMBL127596 Ki 2.3 nM
CCCC(=O)N1CCN(C2CCc3ccc(OC)cc32)CC1 CHEMBL19123 IC50 2.3 nM
CC(=O)NCCc1cccc2ccc(OCCCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12 CHEMBL13985 Ki 2.33 nM
COc1ccc2oc(CC3CCCCC3)c(CCNC(C)=O)c2c1 CHEMBL329299 Ki 2.49 nM
CCOc1nc2ccc(OC)cc2n1CCNC(=O)C1CCC1 CHEMBL4860729 EC50 2.49 nM
CC(C)C(=O)NC[C@@H]1C[C@H]1c1cccc2c1OC(C(C)C)N2 CHEMBL19441 Ki 2.5 nM
COc1cccc(/C(=C\CNC(C)=O)c2ccccc2)c1 CHEMBL425644 Log Ki 2.512 nM
CCCNC(=O)N[C@@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL342393 Ki 2.6 nM
CCCC(=O)N[C@H]1CCN(c2cccc(OC)c2)C1 CHEMBL139497 Ki 2.6 nM
COc1ccc2ccccc2c1[C@@H]1C[C@H]1NC(C)=O CHEMBL2314252 Ki 2.6 nM
CCCC(=O)NCCC(c1ccccc1)c1cccc(OC)c1 CHEMBL374075 Log Ki 2.63 nM
CCC(=O)NCCc1cn(C)c2c(C)cc(OC)cc12 CHEMBL233516 Log Ki 2.63 nM
COc1ccc2[nH]c(-c3cccc4ncccc34)c(CCNC(C)=O)c2c1 CHEMBL5435480 pKi 2.692 nM
Cc1nc2cccc(CCCNC(=O)C3CC3)c2o1 CHEMBL127570 Ki 2.7 nM
COc1ccc2[nH]cc(C(C)(C)CNC(C)=O)c2c1 CHEMBL206472 Ki 2.75 nM
CCCC(=O)NC[C@H](C)Oc1cccc(OC)c1 CHEMBL1223195 pKi 2.754 nM
CCC(=O)NCC(CO)c1cccc2ccc(OC)cc12 CHEMBL4097233 pEC50 2.754 nM
C=CC(=O)NCCc1c(Cc2cccc(OC)c2)oc2ccc(OC)cc12 CHEMBL96916 Ki 2.76 nM
CCC(=O)NCCCc1cccc2nc(C)oc12 CHEMBL124577 Ki 2.8 nM
O=C(N[C@H]1CCN(c2cccc3c2CCO3)C1)C1CC1 CHEMBL139439 Ki 2.8 nM
CCC(=O)NC[C@@H]1CC1c1cccc2oc(CCCCc3ccccc3)cc12 CHEMBL186736 Ki 2.8 nM
COc1ccc2[nH]cc(C(C)CNC(C)=O)c2c1 CHEMBL210147 Ki 2.94 nM
COc1ccc2[nH]c(Oc3ccccc3)c(CCNC(C)=O)c2c1 CHEMBL5403425 pKi 2.951 nM
COc1ccc2c(c1)C(N1CCN(C(=O)C3CC3)CC1)CC2 CHEMBL19339 IC50 3.0 nM
CCCNC(=S)NCC1CCc2ccc3ccc(OC)cc3c21 CHEMBL4288690 Ki 3.0 nM
CCNC(=O)N1CCN(C2CCc3ccc(OC)cc32)CC1 CHEMBL281345 IC50 3.1 nM
COc1ccc2ccc3occ(CCNC(=O)C4CC4)c3c2c1 CHEMBL3759606 EC50 3.2 nM
CCCCCCOc1ccc2oc(Cc3ccccc3)c(CCNC(C)=O)c2c1 CHEMBL315653 Ki 3.21 nM
COc1ccc2[nH]cc(C3(CNC(C)=O)CCC3)c2c1 CHEMBL207960 Ki 3.3 nM
COc1ccc2cc(-c3cccc(CN)c3)cc(CCNC(C)=O)c2c1 CHEMBL477834 Ki 3.4 nM
COc1ccc2oc(=O)cc(CCNC(C)=O)c2c1 CHEMBL3628489 Ki 3.4 nM
COc1cc2[nH]cc(CCNC(C)=O)c2cc1OC CHEMBL124699 Ki 3.5 nM
COc1cccc(N(CCNC(C)=O)c2cccc(CO)c2)c1 CHEMBL5415352 Ki 3.5 nM
COc1ccc2oc(Cc3cccnc3)c(CCNC(C)=O)c2c1 CHEMBL94745 Ki 3.53 nM
CCCC(=O)NCCCc1cccc2ncoc12 CHEMBL124914 Ki 3.7 nM
CCCC(=O)NCCc1c2n(c3ccccc13)CCc1ccccc1-2 CHEMBL9605 Ki 3.7 nM
COc1cccc(N(CCNC(=O)C2CCC2)c2ccccc2)c1 CHEMBL238049 Log Ki 3.715 nM
CCCC(=O)NCC(C)Oc1cccc(OC)c1 CHEMBL1223193 pKi 3.715 nM
CCC(=O)NCCc1c(CN2Cc3ccccc3C2)[nH]c2ccc(OC)cc12 CHEMBL3219327 pKi 3.715 nM
C#CCNC(=O)Cc1c[nH]c2ccc(OC)cc12 CHEMBL3580907 Ki 3.8 nM
CCC(=O)NCC1=C(c2ccccc2)c2ccccc2CC1 CHEMBL4087265 Ki 3.8 nM
CC(=O)NCCC1Cc2cccc3cccc1c23 CHEMBL337295 Ki 3.83 nM
CC(=O)NCCN(c1ccccc1)c1ccccc1 CHEMBL237840 Log Ki 3.89 nM
COc1ccc2[nH]cc(CCc3n[nH]c(=O)o3)c2c1 CHEMBL3580919 Ki 4.0 nM
COc1cnc2cccc(CCNC(C)=O)c2c1 CHEMBL4094436 Ki 4.0 nM
CCC(=O)NCCC1CCc2c(OC)ccc3cccc1c23 CHEMBL340745 Ki 4.03 nM
COc1cccc(Oc2ccc(NC(C)=O)cc2)c1 CHEMBL8094 Ki 4.1 nM
COc1cccc(Nc2ccc(NC(C)=O)cc2)c1 CHEMBL268165 Ki 4.2 nM
CCNC(=O)NCc1cc2c(ccc3ccc(OC)cc32)o1 CHEMBL3759080 Ki 4.2 nM
COC(=O)C(C)c1ccc2cc(OCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)ccc2c1 CHEMBL1095197 Ki 4.22 nM
CC(=O)NCCCc1cccc2ncoc12 CHEMBL124488 Ki 4.3 nM
COc1cccc(O[C@@H](C)CNC(=O)C2CC2)c1 CHEMBL1223130 pKi 4.365 nM
CCC(=O)NCC1(c2cn(C)c3ccc(OC)cc23)CCC1 CHEMBL424693 Ki 4.4 nM
CCc1nc2cccc(CCCNC(=O)C(C)C)c2o1 CHEMBL262890 Ki 4.5 nM
CC(=O)NCCn1c(-c2ccccc2)nc2ccc3c(c21)CCO3 CHEMBL1802021 Ki 4.5 nM
CC(=O)NCCc1c[nH]c2ccc(OCCCCCCNC(=O)Oc3cccc(-c4ccccc4)c3)cc12 CHEMBL4214478 pKi 4.571 nM
CNC(=O)N[C@@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL344449 Ki 4.6 nM
COc1cccc(O[C@@H](C)CNC(C)=O)c1 CHEMBL1223050 pKi 4.677 nM
CCc1nc2cccc(CCCNC(=O)C3CC3)c2o1 CHEMBL125642 Ki 4.7 nM
CCCC(=O)Nc1ccc(Oc2cccc3c2OCCO3)cc1 CHEMBL8032 Ki 4.7 nM
COc1cccc(N(C)c2ccc(NC(=O)C3CC3)cc2)c1 CHEMBL7567 Ki 4.8 nM
CCCCCOC(=O)c1[nH]c2ccc(OC)cc2c1CCNC(C)=O CHEMBL390944 Ki 4.8 nM
C=CCNC(=O)Cc1c[nH]c2ccc(OC)cc12 CHEMBL3580909 Ki 4.9 nM
O=C(NC[C@@H]1C[C@H]1c1cccc2c1C[C@@H](CCCCc1ccccc1)O2)C1CC1 CHEMBL361410 Ki 5.0 nM
COc1ccc2c(I)cn(CCNC(C)=O)c2n1 CHEMBL1760956 Ki 5.0 nM
COc1ccc2oc(-c3c4ccccc4cc4ccccc34)c(CCNC(C)=O)c2n1 CHEMBL3764063 Ki 5.0 nM
COc1ccc2oc(-c3cc4ccccc4c4ccccc34)c(CCNC(C)=O)c2n1 CHEMBL3763537 Ki 5.0 nM
CC(=O)NCCc1c2n(c3ccc(Cl)cc13)CCCc1ccccc1-2 CHEMBL274630 Ki 5.01 nM
CCC(=O)NCCC(c1ccccc1)c1cccc(OC)c1 CHEMBL218774 Log Ki 5.012 nM
CCCC(=O)NCC(C)Sc1cccc(OC)c1 CHEMBL1223196 pKi 5.012 nM
COc1ccc2[nH]c(-c3ccc(-c4ccccc4)cc3)c(CCNC(C)=O)c2c1 CHEMBL5419646 pKi 5.012 nM
COc1ccc2cccc(/C=C/c3n[nH]c(=O)o3)c2c1 CHEMBL4797226 Ki 5.1 nM
O=C(CBr)NCCc1c(Sc2ccc(F)cc2)sc2ccc(F)cc12 CHEMBL1779807 Ki 5.21 nM
CC(=O)NCCCc1cccc2nc(C)oc12 CHEMBL333810 Ki 5.3 nM
COc1cc2c(CCNC(C)=O)c[nH]c2cc1[N+](=O)[O-] CHEMBL298335 Ki 5.3 nM
COc1cccc(C(CCNC(C)=O)c2ccccc2)c1 CHEMBL218773 Log Ki 5.37 nM
CCC(=O)NC[C@@H](CO)c1cccc2ccc(OC)cc12 CHEMBL4079214 pKi 5.495 nM
COc1cccc(N(C)c2ccc(NC(=O)C(C)C)cc2)c1 CHEMBL7990 Ki 5.5 nM
CCOc1ccc2c(c1)c(CCNC(=O)C1CC1)c1n2Cc2ccccc2-1 CHEMBL9600 Ki 5.5 nM
COc1ccc2c(c1)C(CC(c1ccccc1)c1ccccc1)N(C(C)=O)CC2 CHEMBL186452 IC50 5.5 nM
COc1cc2c(CCNC(C)=O)c[nH]c2cc1O CHEMBL127421 Ki 5.5 nM
COc1ccc2[nH]c(Cn3ccc4ccccc43)c(CCNC(C)=O)c2c1 CHEMBL3219324 pKi 5.754 nM
CCCNC(=O)N[C@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL136895 Ki 5.8 nM
COc1ccc2ccc3oc(CCNC(=O)C4CC4)cc3c2c1 CHEMBL3759859 EC50 5.8 nM
COCC(=O)Nc1ccc(Oc2cccc(OC)c2)cc1 CHEMBL7659 Ki 5.9 nM
CCC(=O)N[C@H]1CCN(c2cccc3oc(CCCCc4ccccc4)cc23)C1 CHEMBL186977 Ki 6.0 nM
COc1cnc2cccc(CCNC(=O)CF)c2c1 CHEMBL4097693 Ki 6.0 nM
CCC(=O)NC1Cc2ccccc2N(Cc2ccccc2)C1 CHEMBL4105125 Ki 6.0 nM
COc1ccc(Cc2ccccc2)c(CCNC(C)=O)c1 CHEMBL216158 Log Ki 6.026 nM
CCCC(=O)NC[C@H](C)Sc1cccc(OC)c1 CHEMBL1223198 pKi 6.026 nM
CC(=O)NCCc1c(-c2ccccc2)nc2ccc3c(n12)CCO3 CHEMBL1802020 Ki 6.1 nM
CC(=O)NCC[C@H]1CCc2ccc3nc(C)oc3c21 CHEMBL3648357 Ki 6.1 nM
CCC(=O)NCC[C@H]1CCc2ccc3nc(C)oc3c21 CHEMBL3648360 IC50 6.2 nM
CCNC(=O)NCCc1coc2ccc3ccc(OC)cc3c12 CHEMBL3760044 EC50 6.2 nM
COc1ccc2c(c1)c(CCNC(C)=O)c1n2CCCc2ccccc2-1 CHEMBL275529 Ki 6.31 nM
CC(=O)NCCc1c[nH]c2ccc(OCCCCCCCCNC(=O)Oc3cccc(-c4ccccc4)c3)cc12 CHEMBL4202816 pKi 6.31 nM
CC(C)C(=O)N[C@H]1CCN(c2cccc3c2CCO3)C1 CHEMBL138744 Ki 6.4 nM
COc1ccc2c(c1)c(CCNC(C)=O)cn2Cc1ccccc1 CHEMBL34327 Log Ki 6.457 nM
CCCC(=O)NCCc1c2n(c3ccc(OCC)cc13)CCCc1ccccc1-2 CHEMBL10007 Ki 6.46 nM
CNC(=O)N/C=C/c1c(OC)ccc2ccccc12 CHEMBL2314258 Ki 6.5 nM
CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc(-c4ccc(CO)cc4)cc3)cc12 CHEMBL1094212 Ki 6.53 nM
CCCCOc1ccc2ccc(OC)cc2c1CCNC(=O)CC CHEMBL82135 Ki 6.7 nM
O=C(NCCc1cccc2ccc(OCCCCOc3ccc4cccc(CCNC(=O)C5CC5)c4c3)cc12)C1CC1 CHEMBL1097314 Kb 6.7 nM
CCCNC(=O)CCCc1cccc2c1SCCO2 CHEMBL3260981 IC50 6.7 nM
COc1cccc(S[C@@H](C)CNC(=O)C2CC2)c1 CHEMBL1223192 pKi 6.761 nM
CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4c(c3)C(CCNC(C)=O)CCC4)cc12 CHEMBL1095831 Ki 6.79 nM
CCC(=O)Nc1ccc(Oc2cccc(OC)c2)cc1 CHEMBL266970 Ki 6.8 nM
CC(=O)N[C@@H]1C[C@H]1c1cccc2ccccc12 CHEMBL2314250 Ki 6.8 nM
CCCC(=O)NCCc1c2n(c3ccc(OC)cc13)CCN(C)C2 CHEMBL556908 pKi 6.918 nM
COc1ccc2c(c1)c(CCNC(C)=O)cn2C(=O)OCc1cc(OC)c(OC)cc1[N+](=O)[O-] CHEMBL5195595 pKi 6.918 nM
CCNC(=S)NCc1cc2c(ccc3ccc(OC)cc32)o1 CHEMBL3759677 Ki 7.0 nM
CCC(=O)NCCCc1cccc(OC)c1 CHEMBL297947 Ki 7.07 nM
COc1ccc2c(c1)CCN2Cc1[nH]c2ccc(OC)cc2c1CCNC(C)=O CHEMBL515856 pKi 7.079 nM
COc1cccc(S[C@@H](C)CNC(C)=O)c1 CHEMBL1223053 pKi 7.079 nM
CCOC(=O)Nc1ccc(N(C)c2cccc(OC)c2)cc1 CHEMBL7556 Ki 7.2 nM
CCCC(=O)N[C@H]1CCN(c2cccc3oc(CCCCc4ccccc4)cc23)C1 CHEMBL184144 Ki 7.2 nM
COc1cccc(NCCNC(C)=O)c1 CHEMBL398017 Log Ki 7.413 nM
CCCC(=O)NCC1(c2cn(C)c3ccc(OC)cc23)CC1 CHEMBL209712 Ki 7.5 nM
COc1ccc2cc(-c3cccc(NC(C)=O)c3)cc(CCNC(C)=O)c2c1 CHEMBL489170 Ki 7.54 nM
CCC(=O)NCc1cc2c(OC)cccc2n1Cc1ccccc1 CHEMBL33346 Log Ki 7.586 nM
CCCc1nc2cccc(CCCNC(=O)C3CC3)c2o1 CHEMBL123899 Ki 7.6 nM
COc1ccc2[nH]c(C(=O)OCCCCCCCCCOC(=O)c3[nH]c4ccc(OC)cc4c3CCNC(C)=O)c(CCNC(C)=O)c2c1 CHEMBL226171 Ki 7.75 nM
COc1cccc2c1cc(CCNC(C)=O)n2-c1ccccc1 CHEMBL329979 Log Ki 7.762 nM
COc1ccc2c(c1)c(CCNC(C)=O)c1n2CCN(C)C1 CHEMBL565176 pKi 7.762 nM
O=C(NCCc1c[nH]c2ccc(OCCCOc3ccccc3)cc12)C(F)F CHEMBL3739674 pKi 7.762 nM
COc1ccc2[nH]c(CN3c4ccccc4C[C@H]3CO)c(CCNC(C)=O)c2c1 CHEMBL498493 Ki 7.8 nM
COc1ccc2[nH]c(C(=O)OCCCCCCCCOC(=O)c3[nH]c4ccc(OC)cc4c3CCNC(C)=O)c(CCNC(C)=O)c2c1 CHEMBL387655 Ki 7.92 nM
CC(=O)NCCCc1cccc2c1C[C@@H](CCCCc1ccccc1)O2 CHEMBL362849 Ki 8.0 nM
CCCC(=O)NCCc1c(CN2c3ccccc3CC2C)[nH]c2ccc(OC)cc12 CHEMBL457138 Ki 8.0 nM
COc1ccc2nc(-c3ccccc3)c(CCNC(C)=O)n2c1 CHEMBL1823017 Ki 8.0 nM
O=C(NCCc1cccc2ccc(OCCCOc3ccc4cccc(CCNC(=O)C(F)F)c4c3)cc12)C(F)F CHEMBL3741890 Ki 8.1 nM
CCc1ccc2oc(Cc3ccccc3)c(CCNC(C)=O)c2c1 CHEMBL96333 Ki 8.25 nM
CCOC(=O)Nc1cccc(-c2cc(CCNC(C)=O)c3cc(OC)ccc3c2)c1 CHEMBL478218 Ki 8.3 nM
C=CCC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12 CHEMBL1095195 Ki 8.45 nM
CC(=O)NCC[C@H]1CCc2ccc3nc(C)sc3c21 CHEMBL3648364 IC50 8.5 nM
CCC(=O)NCc1cc2c(OC)cccc2n1Cc1ccc(Cl)cc1 CHEMBL33185 Ki 8.7 nM
COc1ccc2ccc3occ(CNC(=O)C4CC4)c3c2c1 CHEMBL3759816 EC50 8.8 nM
COc1ccc2ccc3occ(CNC(=O)C(C)C)c3c2c1 CHEMBL3759054 EC50 8.8 nM
CC(=O)NCCc1cccc2ccc(OCCCCc3ccccc3)cc12 CHEMBL3741561 pKi 8.913 nM
COc1ccc(N(C)Cc2[nH]c3ccc(OC)cc3c2CCNC(C)=O)cc1 CHEMBL552002 Ki 9.0 nM
CC(=O)NCCc1cccc2ccc(OCCCc3ccccc3)cc12 CHEMBL3739824 Ki 9.0 nM
COc1ccc2oc(-c3c(C)cccc3C)c(CCNC(C)=O)c2n1 CHEMBL3764421 Ki 9.0 nM
CCC(=O)NCCc1c2n(c3ccccc13)CCc1ccccc1-2 CHEMBL273897 Ki 9.33 nM
C=CCC(=O)NCCc1c(CN2Cc3ccccc3C2)[nH]c2ccc(OC)cc12 CHEMBL3219328 pKi 9.333 nM
COc1cccc(OC(C)CNC(C)=O)c1 CHEMBL1222986 pKi 9.55 nM
CCCCCOc1ccc2oc(Cc3ccccc3)c(CCNC(C)=O)c2c1 CHEMBL94919 Ki 9.64 nM
COc1cc2c(cc1OC)C(CC(c1ccccc1)c1ccccc1)N(C(C)=O)CC2 CHEMBL187525 IC50 9.7 nM
COc1cccc(SC(C)CNC(=O)C2CC2)c1 CHEMBL1223131 pKi 9.772 nM
COc1cc2c(cc1OC)C(CC(c1ccccc1)c1ccccc1)N(C=O)CC2 CHEMBL364816 IC50 9.9 nM