CN(Cc1ccc(F)cc1)C(=O)[C@@H](NC(=O)c1ccc2nc(NC(=O)c3ccccc3-c3ccc(C(C)(C)C)cc3)ccc2c1)c1ccccc1 CHEMBL2147287 IC50 0.0004 nM
CC(C)c1ccc(-c2ccccc2C(=O)Nc2ccc3cc(C(=O)N[C@H](C(=O)N(C)Cc4ccc(F)cc4)c4ccccc4)ccc3n2)cc1 CHEMBL2147286 IC50 0.0007 nM
CN(Cc1ccc(F)cc1)C(=O)[C@@H](NC(=O)c1ccc2nc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)ccc2c1)c1ccccc1 CHEMBL2147281 IC50 0.001 nM
CC(C)Oc1ccc(-c2ccccc2C(=O)Nc2ccc3cc(C(=O)N[C@H](C(=O)N(C)Cc4ccc(F)cc4)c4ccccc4)ccc3n2)cc1 CHEMBL2147290 IC50 0.002 nM
CC(C)(C)c1ccc(-c2ccccc2C(=O)Nc2ccc3cc(C(=O)N[C@H](C(=O)NCc4ccc(F)cc4)c4ccccc4)ccc3n2)cc1 CHEMBL2147297 IC50 0.0028 nM
CC(C)Oc1ccc(-c2ccccc2C(=O)Nc2ccc3cc(C(=O)N[C@H](C(=O)NCc4ccc(F)cc4)c4ccccc4)ccc3n2)cc1 CHEMBL2146489 IC50 0.0074 nM
Cc1ccc(-c2ccccc2C(=O)Nc2ccc3cc(C(=O)N[C@H](C(=O)N(C)Cc4ccc(F)cc4)c4ccccc4)ccc3n2)cc1 CHEMBL2147283 IC50 0.0095 nM
CN(Cc1ccccc1)C(=O)[C@@H](NC(=O)c1cc2cc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)ccc2n1C)c1ccccc1 CHEMBL410414 IC50 0.0113 nM
Cc1ccc2c(ncn2CCCCC2(C(=O)NCC(F)(F)F)c3ccccc3-c3ccccc32)c1NC(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL355892 IC50 0.02 nM
CNC(=O)[C@@H](NC(=O)c1ccc2nc(NC(=O)c3ccccc3-c3ccc(C(C)(C)C)cc3)ccc2c1)c1ccccc1 CHEMBL2147296 IC50 0.021 nM
CN(Cc1ccc(F)cc1)C(=O)[C@@H](NC(=O)c1ccc2nc(NC(=O)c3ccccc3-c3ccc(C(C)(C)CO)cc3)ccc2c1)c1ccccc1 CHEMBL2147292 IC50 0.025 nM
Cc1ccc2c(nc(C)n2CCCCC2(C(=O)NCC(F)(F)F)c3ccccc3-c3ccccc32)c1NC(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL355007 IC50 0.03 nM
CC(C)(CO)c1ccc(-c2ccccc2C(=O)Nc2ccc3cc(C(=O)N[C@H](C(=O)NCc4ccc(F)cc4)c4ccccc4)ccc3n2)cc1 CHEMBL2147294 IC50 0.058 nM
CC(C)c1nc2c(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cccc2n1CCCCC1(C(=O)NCC(F)(F)F)c2ccccc2-c2ccccc21 CHEMBL168680 IC50 0.06 nM
CN(Cc1ccc(F)cc1)C(=O)[C@@H](NC(=O)c1ccc2nc(NC(=O)c3ccccc3-c3ccc(C(C)(C)C(=O)O)cc3)ccc2c1)c1ccccc1 CHEMBL2147293 IC50 0.066 nM
CNC(=O)[C@@H](NC(=O)c1ccc2nc(NC(=O)c3ccccc3-c3ccc(OC(C)C)cc3)ccc2c1)c1ccccc1 CHEMBL2147301 IC50 0.101 nM
CN(Cc1ccc(F)cc1)C(=O)[C@@H](NC(=O)c1ccc2nc(NC(=O)c3ccccc3-c3ccc(O)cc3)ccc2c1)c1ccccc1 CHEMBL2147298 IC50 0.105 nM
CC(CO)Oc1ccc(-c2ccccc2C(=O)Nc2ccc3cc(C(=O)N[C@H](C(=O)N(C)Cc4ccc(F)cc4)c4ccccc4)ccc3n2)cc1 CHEMBL2147299 IC50 0.122 nM
Cc1nc2c(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cccc2n1CCCCC1(C(=O)NCC(F)(F)F)c2ccccc2-c2ccccc21 CHEMBL168216 IC50 0.15 nM
O=C(Nc1cccc2c1ncn2CCCCC1(C(=O)NCC(F)(F)F)c2ccccc2-c2ccccc21)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL353385 IC50 0.24 nM
CC(C)(C(=O)O)c1ccc(-c2ccccc2C(=O)Nc2ccc3cc(C(=O)N[C@H](C(=O)NCc4ccc(F)cc4)c4ccccc4)ccc3n2)cc1 CHEMBL2147295 IC50 0.253 nM
Cn1c(C(=O)N[C@H](C(N)=O)c2ccccc2)cc2cc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)ccc21 CHEMBL2147280 IC50 0.345 nM
CNC(=O)[C@@H](NC(=O)c1cc2cc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)ccc2n1C)c1ccccc1 CHEMBL2147279 IC50 0.378 nM
CCCc1ccc(-c2ccccc2C(=O)Nc2ccc3cc(C(=O)N[C@H](C(=O)N(C)Cc4ccc(F)cc4)c4ccccc4)ccc3n2)cc1 CHEMBL2147285 IC50 0.44 nM
CC(Oc1ccc(-c2ccccc2C(=O)Nc2ccc3cc(C(=O)N[C@H](C(=O)N(C)Cc4ccc(F)cc4)c4ccccc4)ccc3n2)cc1)C(=O)O CHEMBL2147300 IC50 0.484 nM
CCc1ccc(-c2ccccc2C(=O)Nc2ccc3cc(C(=O)N[C@H](C(=O)N(C)Cc4ccc(F)cc4)c4ccccc4)ccc3n2)cc1 CHEMBL2147284 IC50 0.55 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)C[C@H](NCc2nccs2)C3)c1-c1ccc(C(F)(F)F)cc1 CHEMBL474892 IC50 0.6 nM
O=C(NC1CCN(CCCCC2(C(=O)NCC(F)(F)F)c3ccccc3-c3ccccc32)CC1)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL354541 IC50 0.8 nM
CN(Cc1ccc(F)cc1)C(=O)[C@@H](NC(=O)c1ccc2nc(NC(=O)c3ccccc3-c3ccc(OC(C)(C)C)cc3)ccc2c1)c1ccccc1 CHEMBL2147291 IC50 0.83 nM
COC(=O)N[C@@H]1Cc2ccc(NC(=O)c3cccc(C)c3-c3ccc(C(F)(F)F)cc3)cc2C1 CHEMBL423915 IC50 0.9 nM
COc1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)ccc1C(=O)N[C@H](C(=O)NCC1CC1)c1ccccc1 CHEMBL126377 IC50 1.01 nM
CCCNC(=O)[C@@H](NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)c(C)c1)c1ccccc1 CHEMBL382891 IC50 1.64 nM
COc1cc(C(=O)N[C@H](C(=O)NCC2CC2)c2ccccc2)ccc1NC(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL207354 IC50 1.68 nM
COc1cc(C(=O)N[C@H](C(=O)N2CCCC2)c2ccccc2)ccc1NC(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL210652 IC50 1.75 nM
Cc1cc(C(=O)N[C@H](C(=O)NCC2CC2)c2ccccc2)ccc1NC(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL378844 IC50 1.78 nM
CCCc1nc2c(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cccc2n1CCCCC1(C(=O)NCC(F)(F)F)c2ccccc2-c2ccccc21 CHEMBL353483 IC50 2.0 nM
CCCNC(=O)[C@@H](NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)c(OC)c1)c1ccccc1 CHEMBL377951 IC50 2.0 nM
CCCN(CC)C(=O)[C@@H](NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)c(OC)c1)c1ccccc1 CHEMBL380472 IC50 2.34 nM
CCCNC(=O)[C@@H](NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)nc1)c1ccccc1 CHEMBL207443 IC50 2.53 nM
CN(Cc1ccc(F)cc1)C(=O)[C@@H](NC(=O)c1ccc2nc(NC(=O)c3ccccc3-c3ccccc3)ccc2c1)c1ccccc1 CHEMBL2147282 IC50 2.8 nM
CCOc1ccc(-c2ccccc2C(=O)Nc2ccc3cc(C(=O)N[C@H](C(=O)N(C)Cc4ccc(F)cc4)c4ccccc4)ccc3n2)cc1 CHEMBL2147289 IC50 2.8 nM
O=C(N[C@H](C(=O)NCc1ccccc1)c1ccccc1)c1ccc(CNC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL207513 IC50 2.97 nM
O=C(NC1COP(=O)(CCCCC2(C(=O)NCC(F)(F)F)c3ccccc3-c3ccccc32)OC1)c1ccccc1-c1nc2ccccc2o1 CHEMBL186836 IC50 3.0 nM
COc1ccc(-c2ccccc2C(=O)Nc2ccc3cc(C(=O)N[C@H](C(=O)N(C)Cc4ccc(F)cc4)c4ccccc4)ccc3n2)cc1 CHEMBL2147288 IC50 3.0 nM
Cc1cc(C(=O)N[C@H](C(=O)N2CCCC2)c2ccccc2)ccc1NC(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL209508 IC50 3.37 nM
Cc1cc(C(=O)N[C@H](C(=O)NCc2ccccc2)c2ccccc2)ccc1NC(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL210704 IC50 3.5 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)C[C@H](NCc2ccccn2)C3)c1-c1ccc(C(F)(F)F)cc1 CHEMBL356310 IC50 3.5 nM
COc1cc(C(=O)N[C@H](C(=O)NCc2ccccc2)c2ccccc2)ccc1NC(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL379030 IC50 3.85 nM
CN(Cc1ccccc1)C(=O)[C@@H](NC(=O)c1ccc(CNC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1)c1ccccc1 CHEMBL208742 IC50 4.11 nM
COC(=O)N[C@H]1Cc2ccc(NC(=O)c3cccc(C)c3-c3ccc(C(F)(F)F)cc3)cc2C1 CHEMBL142450 IC50 4.3 nM
Cc1cc(C(=O)N[C@H](C(=O)N(C)Cc2ccccc2)c2ccccc2)ccc1NC(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL209965 IC50 4.62 nM
O=C(N[C@H]1CC[N@+]([O-])(CCCCC2(C(=O)NCC(F)(F)F)c3ccccc3-c3ccccc32)CC1)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL184354 IC50 5.0 nM
CCCN(CC)C(=O)[C@@H](NC(=O)c1ccc(CNC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1)c1ccccc1 CHEMBL207295 IC50 5.05 nM
CCCN(CC)C(=O)[C@@H](NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1OC)c1ccccc1 CHEMBL210796 IC50 5.28 nM
CCCNC(=O)[C@@H](NC(=O)c1ccc2c(c1)CCN2C(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1)c1ccccc1 CHEMBL382405 IC50 5.53 nM
O=C(N[C@H](C(=O)N1CCCCC1)c1ccccc1)c1ccc(CNC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL377095 IC50 5.67 nM
COc1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)ccc1C(=O)N[C@H](C(=O)N1CCCCC1)c1ccccc1 CHEMBL210048 IC50 6.23 nM
COc1cc(C(=O)N[C@H](C(=O)N2CCCCC2)c2ccccc2)ccc1NC(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL207116 IC50 6.38 nM
COc1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)ccc1C(=O)N[C@H](C(=O)N1CCCC1)c1ccccc1 CHEMBL207461 IC50 6.47 nM
O=C(NC1COP(=O)(CCCCC2(C(=O)NCC(F)(F)F)c3ccccc3-c3ccccc32)OC1)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL365687 IC50 7.0 nM
CCN(CC)C(=O)C(c1ccccc1)C1CCN(c2ccc(NC(=O)c3ccccc3-c3cccnc3)cc2F)CC1 CHEMBL2403023 IC50 7.0 nM
COc1cc(C(=O)N[C@H](C(=O)N(C)Cc2ccccc2)c2ccccc2)ccc1NC(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL209660 IC50 7.14 nM
CN(Cc1ccccc1)C(=O)[C@@H](NC(=O)CSc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1)c1ccccc1 CHEMBL379285 IC50 7.33 nM
O=C(N[C@H](C(=O)N1CCCC1)c1ccccc1)c1ccc(CNC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL383309 IC50 8.15 nM
O=C(CSc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1)N[C@H](C(=O)N1CCCC1)c1ccccc1 CHEMBL377824 IC50 8.27 nM
O=C(NC1COP(=O)(CCCCC2(C(=O)NCC(F)(F)F)c3ccccc3-c3ccccc32)OC1)C1CCCCN1c1ccccc1 CHEMBL360146 IC50 9.0 nM
O=C(NC1COP(=O)(CCCCC2(C(=O)NCC(F)(F)F)c3ccccc3-c3ccccc32)OC1)c1ccccc1-c1nc2ccccc2s1 CHEMBL186494 IC50 9.0 nM
CCCN(CC)C(=O)[C@@H](NC(=O)C1CCN(C(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)CC1)c1ccccc1 CHEMBL376992 IC50 9.43 nM
O=C(Nc1cccc2c1ncn2CCCC1(C(=O)NCC(F)(F)F)c2ccccc2-c2ccccc21)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL354076 IC50 10.0 nM
O=C(NC1COP(=O)(CCCCC2(C(=O)NCC(F)(F)F)c3ccccc3-c3ccccc32)OC1)c1ccccc1 CHEMBL185866 IC50 11.0 nM
O=C(N[C@H](C(=O)N1CCOCC1)c1ccccc1)c1ccc(CNC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL207369 IC50 11.78 nM
O=C(NC1COP(=O)(CCCCC2(C(=O)NCC(F)(F)F)c3ccccc3-c3ccccc32)OC1)c1ccccc1N1CCOCC1 CHEMBL187076 IC50 12.0 nM
CN(Cc1ccccc1)C(=O)[C@@H](NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)nc1)c1ccccc1 CHEMBL410089 IC50 12.97 nM
CCNC(=O)C(c1ccccc1)C1CCN(c2ccc(NC(=O)c3ccccc3-c3ccccc3)cc2F)CC1 CHEMBL2402905 IC50 13.0 nM
COc1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)ccc1C(=O)N[C@H](C(=O)NCc1ccccc1)c1ccccc1 CHEMBL109039 IC50 13.27 nM
CCCN(CC)C(=O)[C@@H](NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)nc1)c1ccccc1 CHEMBL263215 IC50 13.29 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)CC(CNS(=O)(=O)c2cccs2)C3)c1-c1ccc(C(F)(F)F)cc1 CHEMBL143626 IC50 14.0 nM
O=C(NC1COP(=O)(CCCCC2(C(=O)NCC(F)(F)F)c3ccccc3-c3ccccc32)OC1)OCc1ccccc1 CHEMBL187696 IC50 14.0 nM
COc1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)ccc1C(=O)N[C@H](C(=O)N1CCOCC1)c1ccccc1 CHEMBL210289 IC50 14.78 nM
O=C(N[C@H](C(=O)N1CCCC1)c1ccccc1)c1ccc2c(c1)CCN2C(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL208205 IC50 14.9 nM
CCCCN(C)C(=O)[C@@H](NC(=O)c1ccc(CNC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1)c1ccccc1 CHEMBL380666 IC50 15.6 nM
CCCCN(C)C(=O)[C@@H](NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)nc1)c1ccccc1 CHEMBL245300 IC50 16.93 nM
O=C(N[C@H](C(=O)NCC1CC1)c1ccccc1)c1ccc(CNC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL207462 IC50 16.94 nM
CCCCN(C)C(=O)[C@@H](NC(=O)CSc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1)c1ccccc1 CHEMBL208579 IC50 17.27 nM
O=C(N[C@H](C(=O)N1CCCC1)c1ccccc1)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)nc1 CHEMBL379843 IC50 17.38 nM
CCCN(CC)C(=O)[C@@H](NC(=O)c1ccc2c(c1)CCN2C(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1)c1ccccc1 CHEMBL381797 IC50 18.3 nM
COC(=O)NC1CCc2ccc(NC(=O)c3cc(C)cc(C)c3-c3ccc(C(F)(F)F)cc3)cc2CC1 CHEMBL341974 IC50 20.0 nM
COC(=O)NC1CCc2ccc(NC(=O)c3cccc(C)c3-c3ccc(C(F)(F)F)cc3)cc2CC1 CHEMBL142975 IC50 20.0 nM
Cc1cc(C)c(-c2ccc(C(F)(F)F)cc2)c(C(=O)Nc2ccc3c(c2)C[C@H](NS(=O)(=O)c2cccs2)C3)c1 CHEMBL139834 IC50 20.0 nM
CCCCN(C)C(=O)[C@@H](NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1OC)c1ccccc1 CHEMBL207227 IC50 20.51 nM
CCCCOP(=O)(CCCCC1(C(=O)NCC(F)(F)F)c2ccccc2-c2ccccc21)OCCCC CHEMBL282785 IC50 22.0 nM
O=C(N[C@H](C(=O)NCc1ccccc1)c1ccccc1)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)nc1 CHEMBL206965 IC50 22.46 nM
COc1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)ccc1C(=O)N[C@H](C(=O)N(C)Cc1ccccc1)c1ccccc1 CHEMBL207245 IC50 23.13 nM
CCCCN(C)C(=O)[C@@H](NC(=O)C1CCN(C(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)CC1)c1ccccc1 CHEMBL209987 IC50 23.56 nM
COC(=O)NCC1Cc2ccc(NC(=O)c3cccc(C)c3-c3ccc(C(F)(F)F)cc3)cc2C1 CHEMBL142332 IC50 24.0 nM
CCNC(=O)C(c1ccccc1)C1CCN(c2ccc(NC(=O)c3ccccc3-c3ccsc3)cc2F)CC1 CHEMBL2402907 IC50 25.0 nM
CN(Cc1ccccc1)C(=O)[C@@H](NC(=O)c1ccc2c(c1)CCN2C(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1)c1ccccc1 CHEMBL379842 IC50 26.6 nM
O=C(N[C@H](C(=O)NCc1ccccc1)c1ccccc1)c1ccc2c(c1)CCN2C(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL383621 IC50 26.8 nM
O=C(N[C@H](C(=O)N1CCCCC1)c1ccccc1)c1ccc2c(c1)CCN2C(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL208142 IC50 29.0 nM
O=C(N[C@H](C(=O)N1CCCCC1)c1ccccc1)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)nc1 CHEMBL379475 IC50 29.51 nM
CCNC(=O)C(c1ccccc1)C1CCN(c2ccc(C(=O)Nc3ccccc3-c3ccccc3)cc2F)CC1 CHEMBL2403029 IC50 33.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)C[C@H](NS(C)(=O)=O)C3)c1-c1ccc(C(F)(F)F)cc1 CHEMBL359428 IC50 34.0 nM
O=C(N[C@H](C(=O)NCC1CC1)c1ccccc1)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)nc1 CHEMBL378263 IC50 35.4 nM
CCCNC(=O)[C@@H](NC(=O)CSc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1)c1ccccc1 CHEMBL379739 IC50 35.92 nM
COC(=O)NCC1Cc2ccc(NC(=O)c3cc(C)cc(C)c3-c3ccc(C(F)(F)F)cc3)cc2C1 CHEMBL142733 IC50 40.0 nM
COC(=O)N1CCN([C@H]2Cc3ccc(NC(=O)c4cccc(C)c4-c4ccc(C(F)(F)F)cc4)cc3C2)CC1 CHEMBL422295 IC50 40.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)C[C@H](NS(=O)(=O)c2cccs2)C3)c1-c1ccc(C(F)(F)F)cc1 CHEMBL336873 IC50 50.0 nM
COC(=O)N[C@H]1Cc2ccc(NC(=O)c3cccc(C(F)(F)F)c3-c3ccc(C(F)(F)F)cc3)cc2C1 CHEMBL142928 IC50 50.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)CC(NS(=O)(=O)c2cccs2)C3)c1-c1ccc(F)cc1 CHEMBL356091 IC50 50.0 nM
O=C(CSc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1)N[C@H](C(=O)N1CCCCC1)c1ccccc1 CHEMBL381954 IC50 55.84 nM
CCCNC(=O)[C@@H](NC(=O)c1ccc(CNC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1)c1ccccc1 CHEMBL377227 IC50 61.15 nM
COC(=O)N[C@H]1Cc2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2C1 CHEMBL139992 IC50 68.0 nM
O=C(N[C@H](C(=O)N1CCOCC1)c1ccccc1)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)nc1 CHEMBL207213 IC50 69.39 nM
O=C(N[C@H](C(=O)NCc1ccccc1)c1ccccc1)C1CCN(C(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)CC1 CHEMBL210496 IC50 69.52 nM
O=C(CSc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1)N[C@H](C(=O)NCC1CC1)c1ccccc1 CHEMBL377663 IC50 69.84 nM
COC(=O)NCCC1Cc2ccc(NC(=O)c3cccc(C)c3-c3ccc(C(F)(F)F)cc3)cc2C1 CHEMBL344801 IC50 70.0 nM
COc1cccc(C(=O)Nc2ccc3c(c2)CC(NS(C)(=O)=O)C3)c1-c1ccc(Cl)cc1 CHEMBL141881 IC50 70.0 nM
COC(=O)N[C@H]1Cc2ccc(NC(=O)c3cc(C)cc(C)c3-c3ccc(C(F)(F)F)cc3)cc2C1 CHEMBL143284 IC50 70.0 nM
O=C(N[C@H](C(=O)N1CCOCC1)c1ccccc1)c1ccc2c(c1)CCN2C(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL437318 IC50 72.7 nM
CN(Cc1ccccc1)C(=O)[C@@H](NC(=O)C1CCN(C(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)CC1)c1ccccc1 CHEMBL207306 IC50 76.52 nM
COC(=O)NC1CCc2ccc(NC(=O)c3cccc(C)c3-c3ccc(Cl)cc3)cc2CC1 CHEMBL356126 IC50 80.0 nM
CC(=O)NC1Cc2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2C1 CHEMBL143610 IC50 80.0 nM
CN(C)C(=O)NC1Cc2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2C1 CHEMBL143647 IC50 80.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)CCC(NS(C)(=O)=O)CC3)c1-c1ccc(C(F)(F)F)cc1 CHEMBL343874 IC50 80.0 nM
CCCCN(C)C(=O)[C@@H](NC(=O)c1ccc2c(c1)CCN2C(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1)c1ccccc1 CHEMBL377121 IC50 85.5 nM
COC(=O)N[C@@H]1Cc2ccc(NC(=O)c3cc(C)cc(C)c3-c3ccc(C(F)(F)F)cc3)cc2C1 CHEMBL358141 IC50 90.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)CCC(NS(C)(=O)=O)CC3)c1-c1ccc(Cl)cc1 CHEMBL141014 IC50 90.0 nM
Cc1ccc(-c2c(C)cccc2C(=O)Nc2ccc3c(c2)CC(NS(=O)(=O)c2ccccc2)C3)cc1 CHEMBL344439 IC50 93.0 nM
O=C(N[C@H](C(=O)N1CCCCC1)c1ccccc1)C1CCN(C(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)CC1 CHEMBL208099 IC50 95.89 nM
CCCNC(=O)[C@@H](NC(=O)C1CCN(C(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)CC1)c1ccccc1 CHEMBL209026 IC50 96.71 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)CC(NS(=O)(=O)c2ccccc2)C3)c1-c1ccc(Cl)cc1 CHEMBL140754 IC50 100.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)CC(NS(C)(=O)=O)C3)c1-c1ccc(Cl)cc1 CHEMBL412375 IC50 100.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)C[C@@H](NCc2ccccn2)C3)c1-c1ccc(C(F)(F)F)cc1 CHEMBL142972 IC50 100.0 nM
COC(=O)NCC1Cc2ccc(NC(=O)c3cccc(C)c3-c3ccc(Cl)cc3)cc2C1 CHEMBL358538 IC50 100.0 nM
O=C(Nc1ccc2c(c1)CC(NS(=O)(=O)c1ccccc1)C2)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL357886 IC50 105.0 nM
COC(=O)N[C@@H]1Cc2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2C1 CHEMBL142731 IC50 110.0 nM
COc1cccc(C(=O)Nc2ccc3c(c2)CC(NS(=O)(=O)c2ccccc2)C3)c1-c1ccc(Cl)cc1 CHEMBL343406 IC50 110.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)CC(NS(=O)(=O)c2ccccc2)C3)c1-c1ccc(C#N)cc1 CHEMBL141036 IC50 120.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)CC(NS(=O)(=O)c2cccs2)C3)c1-c1ccc(Cl)cc1 CHEMBL423194 IC50 120.0 nM
COC(=O)NC1Cc2ccc(NC(=O)c3cc(C)cc(C)c3-c3ccc(Cl)cc3)cc2C1 CHEMBL343837 IC50 120.0 nM
CS(=O)(=O)NC1Cc2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2C1 CHEMBL140786 IC50 120.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)CCC(NS(=O)(=O)c2cccs2)CC3)c1-c1ccc(C(F)(F)F)cc1 CHEMBL142272 IC50 140.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)C[C@@H](NCc2nccs2)C3)c1-c1ccc(C(F)(F)F)cc1 CHEMBL474893 IC50 140.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)C[C@@H](NCc2cccs2)C3)c1-c1ccc(C(F)(F)F)cc1 CHEMBL474503 IC50 140.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)CC(CNS(C)(=O)=O)C3)c1-c1ccc(C(F)(F)F)cc1 CHEMBL359248 IC50 150.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)C[C@@H](NCc2ccco2)C3)c1-c1ccc(C(F)(F)F)cc1 CHEMBL514764 IC50 150.0 nM
COC(=O)N[C@H]1Cc2ccc(NC(=O)c3cc(C)ccc3-c3ccc(C(F)(F)F)cc3)cc2C1 CHEMBL143514 IC50 170.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)CC(NS(C)(=O)=O)C3)c1-c1ccc(F)cc1 CHEMBL143821 IC50 170.0 nM
Cc1cc(C)c(-c2ccc(C(F)(F)F)cc2)c(C(=O)Nc2ccc3c(c2)C[C@@H](NS(=O)(=O)c2cccs2)C3)c1 CHEMBL344849 IC50 180.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)C[C@@H](NC(C)c2ccccc2)C3)c1-c1ccc(C(F)(F)F)cc1 CHEMBL474301 IC50 180.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)C[C@@H](NS(C)(=O)=O)C3)c1-c1ccc(C(F)(F)F)cc1 CHEMBL142763 IC50 204.0 nM
CCNC(=O)C(c1ccccc1)C1CCN(c2ccc(NC(=O)c3ccccc3-c3cccnc3)cc2F)CC1 CHEMBL2402906 IC50 210.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)CC(NS(=O)(=O)c2ccccc2)C3)c1-c1ccc(F)cc1 CHEMBL344814 IC50 240.0 nM
COC(=O)N[C@H]1Cc2ccc(NC(=O)c3cc(C(F)(F)F)ccc3-c3ccc(C(F)(F)F)cc3)cc2C1 CHEMBL356937 IC50 410.0 nM
Cc1cccc(C(=O)Nc2ccc3c(c2)CC(CNS(C)(=O)=O)C3)c1-c1ccc(Cl)cc1 CHEMBL142616 IC50 500.0 nM
O=C(Nc1ccc2c(c1)C[C@@H](NS(=O)(=O)c1ccccc1)C2)c1ccccc1-c1ccc(C(F)(F)F)cc1 CHEMBL434703 IC50 650.0 nM
O=C(Nc1ccc2c(c1)CC(NS(=O)(=O)c1ccccc1)C2)c1ccccc1-c1ccccc1 CHEMBL143535 IC50 710.0 nM
CCN(CC)C(=O)C(c1ccccc1)N1CCN(c2ccc(NC(=O)c3ccccc3-c3cccnc3)cc2F)CC1 CHEMBL1823342 IC50 710.0 nM
COC(=O)N1CCN([C@@H]2Cc3ccc(NC(=O)c4cccc(C)c4-c4ccc(C(F)(F)F)cc4)cc3C2)CC1 CHEMBL358768 IC50 1000.0 nM