Cc1nnn(C)c1-c1ccc2c3ncc(C(C)(C)O)cc3n([C@H](c3ccccc3)C3CCOCC3)c2c1 CHEMBL5089688 IC50 0.2 nM
CCc1ccc(/C=C2\SC(=O)N(CCCCCNC(=O)c3ccc(Nc4ccc([N+](=O)[O-])c5nonc45)cc3)C2=O)cc1 CHEMBL4100737 Kd 0.6 nM
Cc1nnn(C)c1-c1ccc2c3ncc(C(C)(C)O)cc3n([C@H](c3ccccc3)C3CCOCC3)c2c1F CHEMBL5084636 IC50 0.6 nM
Cc1nnn(C)c1-c1cnc2c3ccc(C(C)(C)O)cc3n([C@H](c3ccccc3)C3CCOCC3)c2c1 CHEMBL4297458 IC50 0.7 nM
[2H]C([2H])([2H])c1nnn(C)c1-c1cc2c(cc1F)c1ncc(C(C)(C)O)cc1n2[C@@H](CCC)c1ncccc1F CHEMBL5075294 IC50 0.7 nM
O=C1NC(=S)S/C1=C/c1ccc(C(=O)NCCCCCNC(=O)c2ccc(Nc3ccc([N+](=O)[O-])c4nonc34)cc2)cc1 CHEMBL4098292 Kd 0.8 nM
Cc1nnn(C)c1-c1cc2c(cc1F)c1ncc(C(C)(C)O)cc1n2[C@H](c1ccccc1)C1CCOCC1 CHEMBL5086429 IC50 0.8 nM
[2H]C([2H])([2H])c1nnn(C)c1-c1cc2c(cc1F)c1ncc(C(C)(C)O)cc1n2[C@H](c1ccccc1)C1CCOCC1 CHEMBL5091333 IC50 1.0 nM
[2H]C([2H])([2H])c1nnn(C)c1-c1cc2c(cc1F)c1ncc(C(C)(C)O)cc1n2[C@H](c1ncccc1F)C1CCOCC1 CHEMBL5084198 IC50 1.3 nM
O=C(NCCCCCCN1C(=O)S/C(=C\c2ccc(F)cc2)C1=O)c1ccc(Nc2ccc([N+](=O)[O-])c3nonc23)cc1 CHEMBL4105521 Kd 1.7 nM
CCc1ccc(/C=C2\SC(=O)N(CCCCCNC(=O)c3ccccc3Nc3ccc([N+](=O)[O-])c4nonc34)C2=O)cc1 CHEMBL4081781 Kd 2.2 nM
[2H]C([2H])([2H])c1nnn(C)c1-c1cc2c(cc1F)c1ncc(C(C)(C)O)cc1n2[C@H](c1cc(C)on1)C1CCOCC1 CHEMBL5090513 IC50 2.4 nM
CCc1ccc(/C=C2\SC(=O)N(CCCCNC(=O)c3ccccc3Nc3ccc([N+](=O)[O-])c4nonc34)C2=O)cc1 CHEMBL4082223 Kd 3.0 nM
Cc1nnn(C)c1-c1cc(F)c2c3ncc(C(C)(C)O)cc3n([C@H](c3ccccc3)C3CCOCC3)c2c1 CHEMBL5090808 IC50 3.4 nM
CCc1ccc(/C=C2\SC(=O)N(CCCCCNC(=O)CNC(=O)c3ccc(Nc4ccc([N+](=O)[O-])c5nonc45)cc3)C2=O)cc1 CHEMBL4060316 Kd 3.6 nM
O=C(NCCCCCN1C(=O)S/C(=C\c2ccc(F)cc2)C1=O)c1ccc(Nc2ccc([N+](=O)[O-])c3nonc23)cc1 CHEMBL4097788 Kd 3.6 nM
CCc1ccc(/C=C2\SC(=O)N(CCCCNC(=O)c3ccc(Nc4ccc([N+](=O)[O-])c5nonc45)cc3)C2=O)cc1 CHEMBL4090075 Kd 4.0 nM
O=C(NCCCCCCN1C(=O)S/C(=C\c2ccc(F)cc2)C1=O)c1ccccc1Nc1ccc([N+](=O)[O-])c2nonc12 CHEMBL4087638 Kd 4.6 nM
CCc1ccc(/C=C2\SC(=O)N(CCCCCNC(=O)CCCCCNC(=O)c3ccc(Nc4ccc([N+](=O)[O-])c5nonc45)cc3)C2=O)cc1 CHEMBL4063155 Kd 5.0 nM
NC(=O)c1ccc(-c2cc(-c3ccc([N+](=O)[O-])cc3)nc(-c3ccco3)c2)cc1 CHEMBL4238599 Kd 6.5 nM
[2H]C([2H])([2H])c1nnn(C)c1-c1cc2c(cn1)c1ncc(C(C)(C)O)cc1n2[C@H](c1ccccc1)C1CCOCC1 CHEMBL5080039 IC50 6.9 nM
O=C1NC(=S)S/C1=C\c1ccc(C(=O)NCCCCCNC(=O)c2ccccc2Nc2ccc([N+](=O)[O-])c3nonc23)cc1 CHEMBL4071241 Kd 10.0 nM
O=C(NCCCCCN1C(=O)S/C(=C\c2ccc(F)cc2)C1=O)c1ccccc1Nc1ccc([N+](=O)[O-])c2nonc12 CHEMBL4079762 Kd 11.0 nM
NC(=O)c1ccc(-c2cc(-c3ccc(-c4nccs4)cc3)nc(-c3ccco3)c2)cc1 CHEMBL4249055 Kd 12.5 nM
[2H]C([2H])([2H])c1nnn(C)c1-c1cc2c(cc1Cl)c1ncc(C(C)(C)O)cc1n2[C@H](c1ccccc1)C1CCOCC1 CHEMBL5069754 IC50 42.0 nM
CCOCCc1c(-c2ccc(N(CC)CC)nc2)c(=O)[nH]c2ccccc12 CHEMBL5433447 pEC50 50.12 nM
O=C(CCCCCNC(=O)c1ccc(Nc2ccc([N+](=O)[O-])c3nonc23)cc1)NCCCCCNC(=O)c1ccc(/C=C2\SC(=S)NC2=O)cc1 CHEMBL4068997 Kd 55.0 nM
CCc1ccc(/C=C2\SC(=O)N(CCCCCNC(=O)c3cccc(Nc4ccc([N+](=O)[O-])c5nonc45)c3)C2=O)cc1 CHEMBL4059866 Kd 110.0 nM
CCOCCn1c(-c2ccc(N(CC)CC)nc2)nc(Br)c1Br CHEMBL5406991 pEC50 158.49 nM
CCOCCc1cc2ccccc2nc1-c1ccc(N(CC)CC)nc1 CHEMBL5416237 pEC50 158.49 nM
CCOCCc1c(-c2ccc(N(CC)CC)nc2)ncc2ccccc12 CHEMBL5431243 pEC50 199.53 nM
CCOCCc1c(-c2ccc(N(CC)CC)nc2)c(=O)n(C)c2ccccc12 CHEMBL5427287 pEC50 199.53 nM
CC(=O)c1ccc2nc(Sc3ccc(/C=C4\SC(=O)N(C(C)C)C4=O)o3)[nH]c2c1 CHEMBL4587215 IC50 260.0 nM
Cc1ccc(C)n1-c1cc(C(=O)N/N=C\c2ccc(S(=O)(=O)O)cc2)ccc1C(=O)O CHEMBL4541510 IC50 291.0 nM
O=C(CNC(=O)c1ccc(Nc2ccc([N+](=O)[O-])c3nonc23)cc1)NCCCCCNC(=O)c1ccc(/C=C2\SC(=S)NC2=O)cc1 CHEMBL4094669 Kd 320.0 nM
Cc1ccc(C)n1-c1cc(C(=O)N2CCc3ccc(C(=O)O)cc3C2)ccc1C(=O)O CHEMBL4560523 IC50 343.0 nM
CC(C)N1C(=O)S/C(=C\c2ccc(Sc3nc4ccc([N+](=O)[O-])cc4[nH]3)o2)C1=O CHEMBL4587175 IC50 360.0 nM
Cc1ccc(C)n1-c1cc(C(=O)N/N=C/c2cccc(C(=O)O)c2)ccc1C(=O)O CHEMBL4575537 IC50 393.0 nM
CCOCCn1c(-c2ccc(N(CC)CC)nc2)nc2ccccc21 CHEMBL5088455 pEC50 398.11 nM
CCN(CC)c1ccc(-c2nc3cccnn3c2Cc2coc(C)n2)cn1 CHEMBL5420545 pEC50 398.11 nM
Cc1nc(Cc2c(-c3ccc(N4[C@@H](C)CC[C@@H]4C)nc3)nc3cccnn23)co1 CHEMBL5404172 pEC50 398.11 nM
O=C1NC(=S)S/C1=C\c1ccc(C(=O)NCCCCCNC(=O)c2cccc(Nc3ccc([N+](=O)[O-])c4nonc34)c2)cc1 CHEMBL4084800 Kd 400.0 nM
CC(C)N1C(=O)S/C(=C\c2ccc(Sc3nc4ccc(NC(=O)c5ccccc5)cc4[nH]3)o2)C1=O CHEMBL4463878 IC50 400.0 nM
Cc1ccc(C)n1-c1cc(C(=O)NN)ccc1C(=O)O CHEMBL4514651 IC50 420.0 nM
CC(C)N1C(=O)S/C(=C\c2ccc(Sc3nc4ccc(OC(F)(F)F)cc4[nH]3)o2)C1=O CHEMBL4436752 IC50 440.0 nM
Cc1ccc(C)n1-c1cc(C(=O)N/N=C\c2cc(F)c(C(=O)O)c(F)c2)ccc1C(=O)O CHEMBL4524924 IC50 480.0 nM
Cc1ccc(C)n1-c1cc(C(=O)N/N=C\c2ccc(C(=O)O)s2)ccc1C(=O)O CHEMBL4521116 IC50 492.0 nM
C[C@@H]1Cc2c(sc(NC(=O)CCN[C@@H]3C[C@H]4CNC[C@H]4C3)c2-c2nc3cnccc3s2)CN1 CHEMBL4573223 IC50 500.0 nM
C[C@@H]1NCCc2c1sc(NC(=O)CCN[C@@H]1C[C@H]3CNC[C@H]3C1)c2-c1nc2cnccc2s1 CHEMBL4582897 IC50 500.0 nM
CC(=O)Nc1sc2c(c1-c1nc3cnccc3s1)C[C@@H](C)N[C@H]2C CHEMBL4514205 IC50 500.0 nM
CCN1Cc2sc(NC(C)=O)c(-c3nc4cnccc4s3)c2C[C@@H]1C CHEMBL4576429 IC50 500.0 nM
CCN1Cc2sc(NC(C)=O)c(-c3nc4cnccc4s3)c2C[C@H]1C CHEMBL4565585 IC50 500.0 nM
O=C(CCNCc1noc2c1CNCC2)Nc1sc2c(c1-c1nc3cnccc3s1)CCNC2 CHEMBL4565380 IC50 500.0 nM
Cc1cccc2c1CCN(CCC(=O)Nc1sc3c(c1-c1nc4cnccc4s1)CCNC3)C2 CHEMBL4529911 IC50 500.0 nM
O=C(CCN1CCn2nccc2C1)Nc1sc2c(c1-c1nc3cnccc3s1)CCNC2 CHEMBL4551355 IC50 500.0 nM
CC1(C#N)CN(CCC(=O)Nc2sc3c(c2-c2nc4cnccc4s2)CCNC3)C1 CHEMBL4592135 IC50 500.0 nM
O=C(CCN1CC(F)(F)C1)Nc1sc2c(c1-c1nc3cnccc3s1)CCNC2 CHEMBL4562205 IC50 500.0 nM
Cc1cc(CNCCC(=O)Nc2sc3c(c2-c2nc4cnccc4s2)CCNC3)no1 CHEMBL4515282 IC50 500.0 nM
Cc1ncc(CNCCC(=O)Nc2sc3c(c2-c2nc4cnccc4s2)CCNC3)s1 CHEMBL4561266 IC50 500.0 nM
O=C(CCN1CCCCC12CNC2)Nc1sc2c(c1-c1nc3cnccc3s1)CCNC2 CHEMBL4527735 IC50 500.0 nM
Cc1nc(CN(C)CCC(=O)Nc2sc3c(c2-c2nc4cnccc4s2)CCNC3)no1 CHEMBL4536903 IC50 500.0 nM
CC(C)c1nc(CNCCC(=O)Nc2sc3c(c2-c2nc4cnccc4s2)CCNC3)no1 CHEMBL4570186 IC50 500.0 nM
O=C(CCN1CC2CCC(C1)O2)Nc1sc2c(c1-c1nc3cnccc3s1)CCNC2 CHEMBL4520270 IC50 500.0 nM
CN1CCN(CCC(=O)Nc2sc3c(c2-c2nc4cnccc4s2)CCNC3)CC1=O CHEMBL4520924 IC50 500.0 nM
Cc1nc(C)c(CNCCC(=O)Nc2sc3c(c2-c2nc4cnccc4s2)CCNC3)s1 CHEMBL4514347 IC50 500.0 nM
CN(CCC(=O)Nc1sc2c(c1-c1nc3cnccc3s1)CCNC2)Cc1cnc(Cl)s1 CHEMBL4535826 IC50 500.0 nM
CC1CN(CCC(=O)Nc2sc3c(c2-c2nc4cnccc4s2)CCNC3)CC(=O)N1 CHEMBL4588391 IC50 500.0 nM
O=C(CCN1CCC(c2ccc(Cl)cc2)CC1)Nc1sc2c(c1-c1nc3cnccc3s1)CCNC2 CHEMBL4519476 IC50 500.0 nM
Cc1coc(CNCCC(=O)Nc2sc3c(c2-c2nc4cnccc4s2)CCNC3)n1 CHEMBL4571867 IC50 500.0 nM
O=C(CCNC(CO)c1ccc(F)cc1)Nc1sc2c(c1-c1nc3cnccc3s1)CCNC2 CHEMBL4555935 IC50 500.0 nM
Cc1cc(C)n(CCNCCC(=O)Nc2sc3c(c2-c2nc4cnccc4s2)CCNC3)n1 CHEMBL4574231 IC50 500.0 nM
O=C(CC[N+]12C[C@H]3CC[C@@H](C1)N32)Nc1sc2c(c1-c1nc3cnccc3s1)CCNC2 CHEMBL4566184 IC50 500.0 nM
O=C(CCN1CC2(C1)CS(=O)(=O)C2)Nc1sc2c(c1-c1nc3cnccc3s1)CCNC2 CHEMBL4573200 IC50 500.0 nM
CC(=O)Nc1sc2c(c1-c1nc3cnccc3s1)CCN(CCN)C2 CHEMBL4483561 IC50 500.0 nM
CCN1[C@@H](C)Cc2c(sc(NC(C)=O)c2-c2nc3cnccc3s2)[C@@H]1C CHEMBL4588045 IC50 500.0 nM
CCN1C(C)Cc2c(sc(NC(C)=O)c2-c2nc3cnccc3s2)C1C CHEMBL4579624 IC50 500.0 nM
CC(=O)Nc1sc2c(c1-c1nc3cnccc3s1)CCN(C(C)C)C2 CHEMBL4542519 IC50 500.0 nM
CC(=O)Nc1sc2c(c1-c1nc3cnccc3s1)CCN(C)C2 CHEMBL4549884 IC50 500.0 nM
CC(=O)Nc1sc2c(c1-c1nc3cnccc3s1)CCC(N)C2 CHEMBL4541892 IC50 500.0 nM
CC(=O)Nc1sc2c(c1-c1nc3cnccc3s1)CC(C)NC2C CHEMBL4590352 IC50 500.0 nM
CC(=O)Nc1sc2c(c1-c1nc3c[n+]([O-])ccc3s1)CCNC2 CHEMBL4531883 IC50 500.0 nM
CC(=O)Nc1sc2c(c1-c1nc3cnccc3s1)C(C)CN(C(C)C)C2 CHEMBL4543899 IC50 500.0 nM
CC(=O)Nc1sc2c(c1-c1nc3cnccc3s1)CCN(C(C)CN1CCOCC1)C2 CHEMBL4532423 IC50 500.0 nM
CC(=O)Nc1sc2c(c1-c1nc3cnccc3s1)C(C)CNC2 CHEMBL4540079 IC50 500.0 nM
CC(=O)Nc1sc2c(c1-c1nc3cnccc3s1)CNC2 CHEMBL4515374 IC50 500.0 nM
CC(=O)Nc1sc2c(c1-c1nc3cccnc3s1)CCNC2 CHEMBL4586689 IC50 500.0 nM
CCN(CC)c1ccc(-c2nc3ccccc3n2Cc2coc(C)n2)cn1 CHEMBL5081154 pEC50 501.19 nM
CCN(CC)c1ccc(-n2nc3ccccc3c2Cc2coc(C)n2)cn1 CHEMBL5428684 pEC50 501.19 nM
Cc1ccc(C)n1-c1cc(C(=O)N/N=C/c2ccc(O)c(O)c2O)ccc1C(=O)O CHEMBL4534756 IC50 531.0 nM
Cc1ccc(C)n1-c1cc(C(=O)N/N=C/c2ccc(S(=O)(=O)O)o2)ccc1C(=O)O CHEMBL4560633 IC50 534.0 nM
CC(C)N1C(=O)S/C(=C\c2cc3ccc(Sc4nc5ccccc5[nH]4)cc3o2)C1=O CHEMBL4439086 IC50 540.0 nM
CC(C)N1C(=O)S/C(=C\c2ccc(Sc3nc4cc(Cl)c(Cl)cc4[nH]3)o2)C1=O CHEMBL4462590 IC50 630.0 nM
CC(C)N1C(=O)S/C(=C\c2ccc(Sc3nc4ccc(C(F)(F)F)cc4[nH]3)o2)C1=O CHEMBL4472238 IC50 640.0 nM
CC(C)c1ccc2nc(Sc3ccc(/C=C4\SC(=O)N(C(C)C)C4=O)o3)[nH]c2c1 CHEMBL4571888 IC50 640.0 nM
CC(C)N1C(=O)S/C(=C\c2ccc(Sc3nc4ccccc4[nH]3)o2)C1=O CHEMBL4546151 IC50 670.0 nM
Cc1ccc(C)n1-c1cc(C(=O)N/N=C\c2cccc(C(=O)O)c2)ccc1C(=O)O CHEMBL4592328 IC50 675.0 nM
Cc1ccc(C)n1-c1cc(C(=O)N/N=C/c2ccc(C(=O)O)o2)ccc1C(=O)O CHEMBL4580673 IC50 708.0 nM
Cc1ccc(C)n1-c1cc(C(=O)O)ccc1C(=O)O CHEMBL4518419 IC50 788.0 nM
CC(C)N1C(=O)S/C(=C\c2ccc(Sc3nc4ccc(Cl)cc4[nH]3)o2)C1=O CHEMBL4441910 IC50 790.0 nM
CC(C)N1C(=O)N/C(=C\c2ccc(Sc3nc4ccccc4[nH]3)o2)C1=O CHEMBL4459178 IC50 830.0 nM
CC(=O)Nc1ccc2nc(Sc3ccc(/C=C4\SC(=O)N(C(C)C)C4=O)o3)[nH]c2c1 CHEMBL4457623 IC50 930.0 nM
CC(C)N1C(=O)S/C(=C\c2ccc(Sc3nc4cccc(Cl)c4[nH]3)o2)C1=O CHEMBL4573749 IC50 980.0 nM
CC(C)N1C(=O)S/C(=C\c2cccc(Oc3nc4ccccc4[nH]3)c2)C1=O CHEMBL4463755 IC50 990.0 nM
Cc1ncc(CO)c(/C=N/NC(=O)c2ccc(C(=O)O)c(-n3c(C)ccc3C)c2)c1O CHEMBL4534386 IC50 1000.0 nM
Cc1ccc(C)n1-c1ncccc1C(=O)O CHEMBL4580970 IC50 1000.0 nM
Cc1ccc(C)n1-c1cccnc1C(=O)O CHEMBL4562506 IC50 1000.0 nM
Cc1ccc(C)n1-c1cc(C(=O)N2CCN(c3cccc(O)c3)CC2)ccc1C(=O)O CHEMBL4588981 IC50 1000.0 nM
COc1cccc(C2CCCN(C(=O)c3ccc(C(=O)O)c(-n4c(C)ccc4C)c3)C2)c1 CHEMBL4526749 IC50 1000.0 nM
Cc1ccc(C)n1-c1cc(CNCc2cccc(C(=O)O)c2)ccc1C(=O)O CHEMBL4575641 IC50 1000.0 nM
Cc1ccc(C)n1-c1cc(C(=O)N2CCN(c3ccccc3C(=O)O)CC2)ccc1C(=O)O CHEMBL4483581 IC50 1000.0 nM
Cc1ccc(C)n1-c1cc(C(=O)N2CCN(c3ccc(C(=O)O)cc3)CC2)ccc1C(=O)O CHEMBL4564656 IC50 1000.0 nM
Cc1ccc(C)n1-c1cc(C(=O)N2CCCC(c3ccc(C(=O)NS(C)(=O)=O)cc3)C2)ccc1C(=O)O CHEMBL4514773 IC50 1000.0 nM
Cc1ccc(C)n1-c1cc(C(=O)N2CCCC(c3ccc(CC(=O)O)cc3)C2)ccc1C(=O)O CHEMBL4551916 IC50 1000.0 nM
Cc1ccc(C)n1-c1cc(-c2nnc(-c3ccc(OCc4ccccc4)c(OCc4ccccc4)c3OCc3ccccc3)o2)ccc1C(=O)O CHEMBL4555437 IC50 1000.0 nM
Cc1ccc(C)n1-c1cc(C(=O)N2CCCC(c3ccc(C(=O)O)cc3)C2)ccc1C(=O)O CHEMBL4584727 IC50 1000.0 nM
Cc1ccc(C)n1-c1cc(C(=O)N2CCCC(c3cccc(C(=O)O)c3)C2)ccc1C(=O)O CHEMBL4526765 IC50 1000.0 nM