COc1ccc(-c2ccc(COC3(C4CC4)CN(C#N)C3)c(F)c2)cc1F CHEMBL4633233 IC50 0.35 nM
Cc1ccc(-c2ccc(COC3CN(C#N)C3)cc2)cc1 CHEMBL4640552 IC50 0.46 nM
COc1cccc(-c2ccc(COC3CN(C#N)C3)c(F)c2)c1 CHEMBL4642793 IC50 0.47 nM
N#CN1CC(OCc2ccc(-c3ccc(F)cc3)cc2)C1 CHEMBL4635208 IC50 0.68 nM
COc1cccc(-c2ccc(COC3CN(C#N)C3)c(C(F)(F)F)c2)c1 CHEMBL4640519 IC50 0.85 nM
COc1cccc(-c2ccc(COC3CN(C#N)C3)cc2)c1OC CHEMBL4644090 IC50 0.88 nM
COc1cccc(-c2ccc(COC3CN(C#N)C3)cc2)c1 CHEMBL4633213 IC50 0.89 nM
COc1ccc(-c2ccc(COC3CN(C#N)C3)cc2)cc1 CHEMBL4649536 IC50 0.94 nM
N#CN1CC(OCc2ccc(Oc3ccccc3)cc2Br)C1 CHEMBL4637701 IC50 1.03 nM
N#CN1CC(OCc2ccc(Oc3ccccc3)cc2)C1 CHEMBL4646880 IC50 1.1 nM
N#CN1CC(OCc2ccc(-c3cccc(OCc4ccccc4)c3)cc2)C1 CHEMBL4632623 IC50 1.4 nM
COc1cccc(-c2ccc(C(=O)NC3(C)CN(C#N)C3)cc2)c1 CHEMBL4635238 IC50 1.58 nM
COc1ccc(-c2ccc3c(c2)CN(C2CN(C#N)C2)C3)cc1F CHEMBL4645560 IC50 1.6 nM
N#CN1CC(OCc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)C1 CHEMBL4646586 IC50 1.6 nM
COc1cccc(-c2ccc(COC3(C)CN(C#N)C3)cc2)c1 CHEMBL4641417 IC50 1.8 nM
COc1ccc(-c2ccc(S(=O)(=O)N[C@H]3C[C@@H](N=C=S)C3)cc2)cc1 CHEMBL4872294 IC50 2.3 nM
N#Cc1ccc(-c2cc(Oc3ccccc3)ccc2COC2CN(C#N)C2)cc1 CHEMBL4643427 IC50 2.5 nM
COc1cccc(-c2ccc(S(=O)(=O)N3CCC34CN(C#N)C4)cc2)c1 CHEMBL4637755 IC50 2.8 nM
N#CN1CC(OCc2ccc(-c3ccccc3)cc2)C1 CHEMBL4642907 IC50 2.8 nM
COc1cccc(-c2ccc(COC3CN(C#N)C3)c(OC)c2)c1 CHEMBL4636322 IC50 2.8 nM
COc1cccc(-c2ccc(S(=O)(=O)NC3(C)CN(C#N)C3)cc2)c1 CHEMBL4643588 IC50 3.2 nM
COc1ccc(-c2ccc(S(=O)(=O)N[C@H]3C[C@@H](N=C=S)C3)cc2)cc1F CHEMBL4848238 IC50 3.2 nM
N#CN1CC(COCc2ccc(-c3ccccc3)cc2)C1 CHEMBL4645262 IC50 3.4 nM
CC[C@H]1OC(=O)[C@@H]1NC(=O)OCCCCCc1ccccc1 CHEMBL4111175 IC50 4.0 nM
Fc1cc(-c2ccc3c(c2)CCO3)ccc1CO[C@H]1C[C@@H](N=C=S)C1 CHEMBL4863412 IC50 4.5 nM
COc1ccc(-c2ccc(COC3(c4cccnc4)CN(C#N)C3)c(F)c2)cc1F CHEMBL4638402 IC50 4.6 nM
CCCCCCC[C@H](C)OC(=O)N[C@H]1C(=O)O[C@H]1C CHEMBL2419811 IC50 5.0 nM
C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCCC1CCCCC1 CHEMBL2419830 IC50 5.0 nM
COc1ccc(-c2cc(Oc3ccccc3)ccc2COC2CN(C#N)C2)cc1 CHEMBL4639554 IC50 5.7 nM
COc1ncccc1-c1ccc(COC2CN(C#N)C2)cc1 CHEMBL4638779 IC50 5.8 nM
CC[C@H]1OC(=O)[C@@H]1NC(=O)OCc1ccc(-c2ccccc2)cc1 CHEMBL4108761 IC50 6.0 nM
C[C@H]1[C@H](NC(=O)OCCCCC2CCCCC2)C(=O)N1Oc1ccc(S(C)(=O)=O)cc1 CHEMBL4101070 IC50 6.0 nM
C[C@H]1[C@H](NC(=O)OCCCCC2CCCCC2)C(=O)N1Oc1ccccc1S(C)(=O)=O CHEMBL4093333 IC50 6.0 nM
C[C@H]1[C@H](NC(=O)OCCCCC2CCCCC2)C(=O)N1c1cccc(S(C)(=O)=O)c1 CHEMBL4647961 IC50 6.0 nM
O=C(N[C@H]1CNC1=O)OCCCCC1CCCCC1 CHEMBL3770726 IC50 6.0 nM
N#CN1CC(OCc2ccc(-c3ccc4c(c3)OCCO4)cc2)(c2ccccc2)C1 CHEMBL4643074 IC50 6.1 nM
COc1ccc(-c2ccc(S(=O)(=O)N[C@H]3C[C@@H](N=C=S)C3)nc2)cc1 CHEMBL4868148 IC50 6.3 nM
COc1cccc(-c2ccc(C(=O)N3CCC34CN(C#N)C4)cc2)c1 CHEMBL4649749 IC50 6.5 nM
N#Cc1ccccc1-c1cc(Oc2ccccc2)ccc1COC1CN(C#N)C1 CHEMBL4634952 IC50 6.6 nM
C[C@@H]1OC(=O)[C@@H]1NC(=O)OCc1ccc(-c2ccccc2)cc1 CHEMBL2419814 IC50 7.0 nM
C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCCc1ccccc1 CHEMBL2064166 IC50 7.0 nM
CCCCc1ccc(COC(=O)N[C@H]2CNC2=O)cc1 CHEMBL3770896 IC50 7.0 nM
COc1ccc(-c2ccc(OC(=O)N[C@H]3C[C@@H](N=C=S)C3)cc2)cc1 CHEMBL4862347 IC50 7.0 nM
COc1ccc(-c2ccc(C(=O)N[C@H]3C[C@@H](N=C=S)C3)nc2)cc1 CHEMBL4845987 IC50 7.6 nM
C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCC1CCCCC1 CHEMBL3353547 IC50 8.0 nM
S=C=N[C@H]1C[C@@H](OCc2ccc(-c3ccc4occc4c3)cn2)C1 CHEMBL4854759 IC50 8.3 nM
S=C=NC1CN(CCCCCCc2ccccc2)C1 CHEMBL4863536 IC50 8.3 nM
N#CN1CC(OCc2ccc(Oc3ccccc3)cc2-c2ccccc2)C1 CHEMBL4637132 IC50 8.5 nM
Fc1cc(-c2ccc3c(c2)OCO3)ccc1CO[C@H]1C[C@@H](N=C=S)C1 CHEMBL4865193 IC50 8.8 nM
CC[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCCc1ccccc1 CHEMBL3972433 IC50 9.0 nM
O=C(CCCCCc1cccc(Cl)c1)N1CCOC1=O CHEMBL4215669 IC50 9.0 nM
COc1cccc(-c2ccc(COC3(c4ccccc4)CN(C#N)C3)cc2)c1 CHEMBL4641400 IC50 9.1 nM
N#CN1CC(OCc2ccc(-c3ccc4c(c3)OCO4)cc2)(c2ccccc2)C1 CHEMBL4637050 IC50 9.2 nM
CC(OC(=O)N[C@H]1C(=O)O[C@H]1C)c1ccc(-c2ccccc2)cc1 CHEMBL3982757 IC50 10.0 nM
C[C@H]1[C@H](NC(=O)OCCCCC2CCCCC2)C(=O)N1Oc1cccc(S(C)(=O)=O)c1 CHEMBL4065712 IC50 10.0 nM
COc1cccc(-c2ccc(C(OC3CN(C#N)C3)c3ccccc3)cc2)c1 CHEMBL4632779 IC50 11.6 nM
Fc1cc(-c2ccc3c(c2)OCCO3)ccc1CO[C@H]1C[C@@H](N=C=S)C1 CHEMBL4861067 IC50 11.8 nM
O=C(N[C@H]1CNC1=O)OCc1ccc(C2CCCCC2)cc1 CHEMBL3770525 IC50 12.0 nM
CC(C)[C@H]1OC(=O)[C@@H]1NC(=O)OC(C)(C)CCCCc1ccccc1 CHEMBL4111254 IC50 12.0 nM
N#CN1CC(OCc2ccc(-c3cccnc3)cc2)C1 CHEMBL4636756 IC50 12.0 nM
CC(CCCCc1ccccc1)OC(=O)N[C@H]1C(=O)O[C@H]1C CHEMBL2419808 IC50 14.0 nM
COc1ccc(-c2ccc(C(C)O[C@H]3C[C@@H](N=C=S)C3)c(F)c2)cc1F CHEMBL4876872 IC50 14.6 nM
CC[C@@H]1OC(=O)[C@@H]1NC(=O)OCc1ccc(-c2ccccc2)cc1 CHEMBL3942817 IC50 15.0 nM
COc1cnc(-c2ccc(CO[C@H]3C[C@@H](N=C=S)C3)cn2)cc1F CHEMBL4873515 IC50 15.0 nM
CON1C[C@H](NC(=O)OCCCCC2CCCCC2)C1=O CHEMBL4100949 IC50 16.0 nM
CCOCc1ccc(O[C@H]2C[C@H]3CC[C@@H](C2)N3S(=O)(=O)c2c(C)n[nH]c2C)cc1 CHEMBL4878464 IC50 16.0 nM
C[C@H]1[C@H](NC(=O)OCCCCC2CCCCC2)C(=O)N1Oc1ccc([N+](=O)[O-])cc1 CHEMBL4084145 IC50 17.0 nM
COC(=O)c1ccc(ON2C(=O)[C@@H](NC(=O)OCCCCC3CCCCC3)[C@@H]2C)cc1 CHEMBL4096232 IC50 17.0 nM
CCCCc1cnc(O[C@H]2C[C@H]3CC[C@@H](C2)N3S(=O)(=O)c2c(C)n[nH]c2C)cn1 CHEMBL4864438 IC50 17.0 nM
C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCOCc1ccccc1 CHEMBL2419828 IC50 18.0 nM
CC(C)[C@H]1OC(=O)[C@@H]1NC(=O)OCCCCCc1ccccc1 CHEMBL4112296 IC50 19.0 nM
CCCCCCc1ccc(O[C@H]2C[C@H]3CC[C@@H](C2)N3S(=O)(=O)c2c(C)n[nH]c2C)cc1 CHEMBL4863119 IC50 19.0 nM
COc1cnc(-c2cnc(CO[C@H]3C[C@@H](N=C=S)C3)c(F)c2)cc1F CHEMBL4862325 IC50 19.5 nM
COc1ccc(-c2ccc(CO[C@H]3C[C@@H](N=C=S)C3)nc2)cc1F CHEMBL4874855 IC50 20.0 nM
COc1ccc(-c2ccc(CO[C@H]3C[C@@H](N=C=S)C3)c(F)c2)cc1F CHEMBL4867452 IC50 20.6 nM
CN(Cc1ccc(-c2ccccc2)cc1)C1CN(C#N)C1 CHEMBL4648948 IC50 20.8 nM
Cc1ccc(ON2C(=O)[C@@H](NC(=O)OCCCCC3CCCCC3)[C@@H]2C)cc1 CHEMBL4073792 IC50 21.0 nM
O=C(N[C@H]1CNC1=O)OCc1ccc2c(c1)OC(F)(F)O2 CHEMBL3771111 IC50 22.0 nM
COc1cccc(-c2ccc(CO[C@H]3C[C@@H](N=C=S)C3)cc2)c1 CHEMBL4860338 IC50 22.0 nM
COc1ccc(CCCCCC(=O)N[C@H]2C[C@@H](N=C=S)C2)cc1 CHEMBL4857027 IC50 22.5 nM
CC(C)[C@H]1OC(=O)[C@@H]1NC(=O)OCc1ccc(-c2ccccc2)cc1 CHEMBL4112084 IC50 23.0 nM
C[C@H]1[C@H](NC(=O)OCCCCC2CCCCC2)C(=O)N1Oc1ccccc1 CHEMBL4100592 IC50 23.0 nM
CCCCc1ccc(O[C@@H]2C[C@H]3CC[C@@H](C2)N3CS(=O)(=O)c2c(C)n[nH]c2C)cc1 CHEMBL4643312 IC50 23.0 nM
CCCCc1ccc(O[C@H]2C[C@H]3CC[C@@H](C2)N3S(=O)(=O)c2c(C)n[nH]c2C)cc1 CHEMBL4848541 IC50 23.0 nM
COc1cnc(-c2ccc(CO[C@H]3C[C@@H](N=C=S)C3)[n+]([O-])c2)cc1F CHEMBL4845984 IC50 23.5 nM
COc1ccccc1-c1cc(Oc2ccccc2)ccc1COC1CN(C#N)C1 CHEMBL4637179 IC50 23.7 nM
Cc1ccc(-c2ccc(CO[C@H]3C[C@@H](N=C=S)C3)cc2)cc1 CHEMBL4847120 IC50 26.0 nM
N#CN1CC[C@@H](OCc2ccc(-c3ccccc3)cc2)C1 CHEMBL4645479 IC50 26.4 nM
COc1ccc(-c2ccc(C(=O)N[C@H]3C[C@@H](N=C=S)C3)nc2)cc1F CHEMBL4864610 IC50 26.6 nM
N#CN1CC(Oc2ccc(-c3ccccc3)cc2)C1 CHEMBL4633126 IC50 29.0 nM
S=C=NCCCCCCCCCCc1ccccc1 CHEMBL4218684 IC50 30.0 nM
COc1ccc(-c2ccc(CO[C@H]3C[C@@H](N=C=S)C3)nc2)nc1 CHEMBL4873607 IC50 30.4 nM
C[C@H]1[C@H](NC(=O)OCCCCC2CCCCC2)C(=O)N1Oc1ccc(C(F)(F)F)cc1 CHEMBL4062436 IC50 31.0 nM
O=C(N[C@H]1CNC1=O)OCCCCC1CCCC1 CHEMBL3769844 IC50 33.0 nM
CCCCCCCCOC(=O)N[C@H]1CNC1=O CHEMBL3770558 IC50 33.0 nM
COc1ccc(-c2ccc(O[C@H]3C[C@@H](N=C=S)C3)cc2)cc1F CHEMBL4860428 IC50 35.9 nM
Cc1ccc(O[C@H]2C[C@H]3CC[C@@H](C2)N3S(=O)(=O)c2c(C)n[nH]c2C)cc1 CHEMBL4871884 IC50 36.0 nM
CC(C)[C@@H]1OC(=O)[C@@H]1NC(=O)OCc1ccc(-c2ccccc2)cc1 CHEMBL4111700 IC50 37.0 nM
C[C@H]1[C@H](NC(=O)OCCCCC2CCCCC2)C(=O)N1Oc1ccc(-c2ccccc2)cc1 CHEMBL4074330 IC50 39.0 nM
COc1ccncc1-c1ccc(COC2CN(C#N)C2)cc1 CHEMBL4641015 IC50 40.0 nM
CCOCc1cnc(O[C@H]2C[C@H]3CC[C@@H](C2)N3S(=O)(=O)c2c(C)n[nH]c2C)cn1 CHEMBL4875895 IC50 42.0 nM
COc1ccc(-c2cc(CO[C@H]3C[C@@H](N=C=S)C3)on2)cc1 CHEMBL4866607 IC50 43.6 nM
O=C(N[C@H]1CNC1=O)OCCCC1CCCCC1 CHEMBL3769455 IC50 44.0 nM
CCCOc1ccc(COC(=O)N[C@H]2CNC2=O)cc1 CHEMBL3769689 IC50 48.0 nM
C[C@H]1[C@H](NC(=O)OCCCCC2CCCCC2)C(=O)N1Oc1ccc(Oc2ccccc2)cc1 CHEMBL4068961 IC50 48.0 nM
O=C(N[C@H]1CNC1=O)OCCCCCC1CCCCC1 CHEMBL3770490 IC50 49.0 nM
C[C@H]1[C@H](NC(=O)OCCCCC2CCCCC2)C(=O)N1OCCCS(C)(=O)=O CHEMBL4085109 IC50 49.0 nM
CCc1ccc(O[C@H]2C[C@H]3CC[C@@H](C2)N3S(=O)(=O)c2c(C)n[nH]c2C)cc1 CHEMBL4875599 IC50 51.0 nM
CCCc1ccc(COC(=O)N[C@H]2CNC2=O)cc1 CHEMBL3770240 IC50 52.0 nM
COc1ccc(C2CC(C(=O)N[C@H]3C[C@@H](N=C=S)C3)C2)cc1 CHEMBL4864937 IC50 55.9 nM
CON1C[C@@H](NC(=O)OCCCCC2CCCCC2)C1=O CHEMBL4084489 IC50 56.0 nM
COc1ccc(-c2ccc(CO[C@H]3C[C@@H](N=C=S)C3)c(F)c2)cc1OC CHEMBL4876281 IC50 58.9 nM
Fc1cc(-c2ccc3c(c2)OCC3)ccc1CO[C@H]1C[C@@H](N=C=S)C1 CHEMBL4847169 IC50 59.3 nM
COc1ccc(CCCC(=O)N[C@H]2C[C@@H](N=C=S)C2)cc1 CHEMBL4865146 IC50 62.0 nM
CC(C)[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCCc1ccccc1 CHEMBL4109789 IC50 63.0 nM
Fc1cc(-c2cccc(C(F)(F)F)c2)ccc1CO[C@H]1C[C@@H](N=C=S)C1 CHEMBL4860382 IC50 67.2 nM
COc1cccc(OC)c1-c1ccc(COC2CN(C#N)C2)cc1 CHEMBL4636537 IC50 67.5 nM
CON1C(=O)[C@@H](NC(=O)OCCCCC2CCCCC2)[C@@H]1C CHEMBL4104985 IC50 69.0 nM
CCOc1ccc(-c2ccc(CO[C@H]3C[C@@H](N=C=S)C3)c(F)c2)cc1F CHEMBL4859507 IC50 69.2 nM
O=C(N[C@H]1CNC1=O)OCc1ccc(C2CCCC2)cc1 CHEMBL3770567 IC50 71.0 nM
O=C(N[C@H]1CNC1=O)OCCCCc1ccc(C(F)(F)F)cc1 CHEMBL3769639 IC50 73.0 nM
COc1ccc(-c2ccc3c(c2)CN([C@H]2C[C@@H](N=C=S)C2)C3)cc1F CHEMBL4850450 IC50 74.2 nM
Cn1nccc1-c1ccc(C(OC2CN(C#N)C2)c2ccccc2)cc1 CHEMBL4643165 IC50 74.7 nM
CC(=O)CCCON1C(=O)[C@@H](NC(=O)OCCCCC2CCCCC2)[C@@H]1C CHEMBL4103059 IC50 75.0 nM
O=C(N[C@H]1CNC1=O)OCCCCC1CCC(F)(F)CC1 CHEMBL3769678 IC50 76.0 nM
COCCCON1C(=O)[C@@H](NC(=O)OCCCCC2CCCCC2)[C@@H]1C CHEMBL4093943 IC50 88.0 nM
COc1ccc(-c2ccc3c(c2)CCN([C@H]2C[C@@H](N=C=S)C2)C3)cc1F CHEMBL4868739 IC50 89.0 nM
N#CN1CC(OC(c2ccccc2)c2cc(-c3ccon3)cc(-c3ccon3)c2)C1 CHEMBL4644779 IC50 91.2 nM
COc1ccc(-c2cc(C(=O)N[C@H]3C[C@@H](N=C=S)C3)on2)cc1 CHEMBL4845934 IC50 91.5 nM
S=C=N[C@H]1C[C@@H](OCc2ccc(-c3ccccc3)cc2)C1 CHEMBL4851335 IC50 93.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1[C@@H]2CC[C@H]1C[C@@H](Oc1ccccc1)C2 CHEMBL4861341 IC50 93.0 nM
Fc1cc(-c2ccc(OC(F)(F)F)c(F)c2)ccc1CO[C@H]1C[C@@H](N=C=S)C1 CHEMBL4851995 IC50 97.1 nM
Fc1cc(-c2cccc(OCc3ccccc3)c2)ccc1CO[C@H]1C[C@@H](N=C=S)C1 CHEMBL4860906 IC50 99.8 nM
CCCCCCCCCCC(=O)N[C@H]1CNC1=O CHEMBL4212923 IC50 100.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1[C@@H]2CC[C@H]1C[C@@H](Oc1ccc(CCC(C)C)cc1)C2 CHEMBL4877336 IC50 114.0 nM
CCCCCCCOC(=O)N[C@H]1CNC1=O CHEMBL3770640 IC50 122.0 nM
COc1ccc(C23CC(C(=O)N[C@H]4C[C@@H](N=C=S)C4)(C2)C3)cc1 CHEMBL4874040 IC50 127.8 nM
O=C(N[C@H]1CNC1=O)OCc1ccc2c(c1)CCC2 CHEMBL3771169 IC50 130.0 nM
CCCON1C(=O)[C@@H](NC(=O)OCCCCC2CCCCC2)[C@@H]1C CHEMBL4097278 IC50 133.0 nM
COc1ccc(N2CCC(C(=O)N[C@H]3C[C@@H](N=C=S)C3)CC2)cc1 CHEMBL4875831 IC50 137.0 nM
O=C(N[C@H]1CNC1=O)OCc1ccc2c(c1)CCCC2 CHEMBL3771196 IC50 140.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1[C@@H]2CC[C@H]1C[C@@H](Oc1ccc(F)cc1)C2 CHEMBL4873115 IC50 143.0 nM
COc1cc(-c2ccc(CO[C@H]3C[C@@H](N=C=S)C3)c(F)c2)ccc1F CHEMBL4877911 IC50 155.0 nM
CCc1ccc(COC(=O)N[C@H]2CNC2=O)cc1 CHEMBL3769452 IC50 160.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1[C@@H]2CC[C@H]1C[C@@H](Oc1ccccn1)C2 CHEMBL4861841 IC50 162.0 nM
CSCCCON1C(=O)[C@@H](NC(=O)OCCCCC2CCCCC2)[C@@H]1C CHEMBL4066385 IC50 167.0 nM
FC1(F)Oc2ccc(-c3ccc(CO[C@H]4C[C@@H](N=C=S)C4)nc3)cc2O1 CHEMBL4860002 IC50 171.4 nM
COc1ccc(O[C@H]2C[C@H]3CC[C@@H](C2)N3S(=O)(=O)c2c(C)n[nH]c2C)cc1 CHEMBL4879033 IC50 175.0 nM
COc1ccc(-c2ccc(CN3CC(N=C=S)C3)c(F)c2)cc1F CHEMBL4855935 IC50 176.0 nM
CCOCCON1C(=O)[C@@H](NC(=O)OCCCCC2CCCCC2)[C@@H]1C CHEMBL4099706 IC50 187.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1[C@@H]2CC[C@H]1C[C@@H](Oc1ccc(C(F)(F)F)cc1)C2 CHEMBL4857016 IC50 212.0 nM
CC(C)c1ccc(-c2ccc(CO[C@H]3C[C@@H](N=C=S)C3)c(F)c2)cc1F CHEMBL4876978 IC50 227.1 nM
CCc1ccc(CCCCOC(=O)N[C@H]2CNC2=O)cc1 CHEMBL3770354 IC50 230.0 nM
CCS(=O)(=O)c1ccccc1C(=O)N1CCN(c2nc3ccc(F)cc3s2)C[C@@H]1C CHEMBL4641320 IC50 230.0 nM
CCCS(=O)(=O)c1ccccc1C(=O)N1CCN(c2nc3ccc(F)cc3s2)C[C@@H]1C CHEMBL4871398 IC50 230.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1[C@@H]2CC[C@H]1C[C@@H](Oc1cnccn1)C2 CHEMBL4848387 IC50 230.0 nM
CC(C)(C)[C@@H]1OC(=O)[C@H]1NC(=O)OCCCCCc1ccccc1 CHEMBL3940588 IC50 234.0 nM
C[C@@H]1NC(=O)[C@H]1NC(=O)OCCCCC1CCCCC1 CHEMBL3770695 IC50 240.0 nM
CCCCCCCCCC(=O)N[C@H]1CNC1=O CHEMBL4211436 IC50 240.0 nM
COc1ccc(-c2ccc(CO[C@H]3C[C@@H](N=C=S)C3(C)C)nc2)cc1F CHEMBL4869018 IC50 246.0 nM
CC(C)(C)[C@H]1OC(=O)[C@@H]1NC(=O)OCCCCCc1ccccc1 CHEMBL4108283 IC50 267.0 nM
CC(C)(C)[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCCc1ccccc1 CHEMBL4109824 IC50 278.0 nM
O=C(CCCCCCC1CCCCC1)N[C@H]1CNC1=O CHEMBL4208021 IC50 280.0 nM
Cc1ccccc1O[C@H]1C[C@H]2CC[C@@H](C1)N2S(=O)(=O)c1c(C)n[nH]c1C CHEMBL4869873 IC50 291.0 nM
O=C(N[C@H]1CNC1=O)OCCCCCc1ccccc1 CHEMBL3770549 IC50 298.0 nM
COc1ncccc1-c1ccc(CO[C@H]2C[C@@H](N=C=S)C2)c(F)c1 CHEMBL4853981 IC50 303.6 nM
CC(C)(C)c1ccc(COC(=O)N[C@H]2CNC2=O)cc1 CHEMBL3769597 IC50 310.0 nM
C[C@@H]1OC(=O)[C@@H]1NC(=O)CCCCCCc1ccccc1 CHEMBL2069631 IC50 314.0 nM
N#CN1CC[C@H](OCc2ccc(-c3ccccc3)cc2)C1 CHEMBL4643680 IC50 315.0 nM
CCCCC1CCC(OC(=O)N[C@H]2CNC2=O)CC1 CHEMBL3770519 IC50 323.0 nM
CCCc1n[nH]c(C)c1S(=O)(=O)N1CCC(Oc2cnccn2)CC1 CHEMBL4866583 IC50 330.0 nM
CCCCCCCCC(=O)N[C@H]1CNC1=O CHEMBL3770509 IC50 340.0 nM
COc1ccc(-c2ccc3c(c2)CN([C@H]2C[C@@H](N=C=S)C2)CC3)cc1F CHEMBL4856189 IC50 356.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1[C@@H]2CCC[C@H]1C[C@@H](Oc1cnccn1)C2 CHEMBL4865423 IC50 370.0 nM
COc1ccc(-c2ccc(CO[C@H]3CC[C@@H](N=C=S)CC3)cc2)cc1F CHEMBL4864313 IC50 386.0 nM
CCCCCON1C(=O)[C@@H](NC(=O)OCCCCC2CCCCC2)[C@@H]1C CHEMBL4070087 IC50 387.0 nM
CCCOc1ccc(O[C@H]2C[C@H]3CC[C@@H](C2)N3S(=O)(=O)c2c(C)n[nH]c2C)cc1 CHEMBL4869850 IC50 450.0 nM
CC(C)(C)[C@H]1OC(=O)[C@@H]1NC(=O)OCc1ccc(-c2ccccc2)cc1 CHEMBL4115242 IC50 465.0 nM
COc1ccc(-c2ccc(CO[C@]3(C)C[C@H](N=C=S)C3)c(F)c2)cc1F CHEMBL4845862 IC50 480.0 nM
COc1ccc(-c2noc(CO[C@H]3C[C@@H](N=C=S)C3)n2)cc1 CHEMBL4864478 IC50 493.0 nM
CC(C)(C)[C@@H]1OC(=O)[C@H]1NC(=O)OCc1ccc(-c2ccccc2)cc1 CHEMBL3978258 IC50 507.0 nM
O=C(N[C@H]1CNC1=O)OCc1ccc(-c2ccccc2)cc1 CHEMBL3770031 IC50 513.0 nM
Cn1cc(-c2ccc(CO[C@H]3C[C@@H](N=C=S)C3)c(F)c2)cn1 CHEMBL4858757 IC50 517.4 nM
COc1ccc(CCCCOC(=O)N[C@H]2CNC2=O)cc1 CHEMBL3770722 IC50 520.0 nM
C[C@@H]1OC(=O)[C@@H]1NC(=O)OC12CC3CC(CC(C3)C1)C2 CHEMBL3961826 IC50 540.0 nM
Cc1ccc(-c2ccc(CO[C@H]3C[C@H](N=C=S)C3)cc2)cc1 CHEMBL4878483 IC50 580.0 nM
CCCCCCCCCCCCCCCN=C=S CHEMBL4207058 IC50 600.0 nM
Cc1cccc(OC2CC3CCC(C2)N3S(=O)(=O)c2c(C)n[nH]c2C)c1 CHEMBL4867701 IC50 614.0 nM
CCc1n[nH]c(C)c1S(=O)(=O)N1CCC(Oc2cnccn2)CC1 CHEMBL4873294 IC50 620.0 nM
Cc1[nH]nc(C(C)C)c1S(=O)(=O)N1CCC(Oc2cnccn2)CC1 CHEMBL4846675 IC50 640.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1[C@@H]2CC[C@H]1C[C@H](Oc1ccccc1)C2 CHEMBL4879204 IC50 655.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1C[C@H]2CCC[C@@H](C1)[C@@H]2Oc1cnccn1 CHEMBL4852010 IC50 690.0 nM
CC(=O)Oc1cccc2c1C(=O)c1c(OC(C)=O)cc(C(=O)O)cc1C2=O CHEMBL41286 IC50 700.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1[C@@H]2CC[C@H]1C[C@@H](Oc1ccc(C(C)C)cc1)C2 CHEMBL4853024 IC50 744.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1[C@@H]2CC[C@H]1C[C@@H](Oc1ccc(C#N)cc1)C2 CHEMBL4855742 IC50 757.0 nM
Cc1[nH]nc(C(C)(C)C)c1S(=O)(=O)N1CCC(Oc2cnccn2)CC1 CHEMBL4858013 IC50 780.0 nM
COc1ccc(-c2cnc(C(=O)N[C@H]3C[C@@H](N=C=S)C3)cn2)cc1 CHEMBL4849452 IC50 853.2 nM
CC(C)(C)[C@@H]1OC(=O)[C@@H]1NC(=O)OCc1ccc(-c2ccccc2)cc1 CHEMBL4110928 IC50 897.0 nM
CCCCc1n[nH]c(C)c1S(=O)(=O)N1CCC(Oc2cnccn2)CC1 CHEMBL4855017 IC50 910.0 nM