CN(C)CCn1cc(-c2ccn3c(-c4ccc(C(N)=O)c(OCc5cccc(F)c5)c4)cnc3c2)cn1 CHEMBL4062453 IC50 1.0 nM
CN(C)CCn1cc(-c2ccn3c(-c4ccc(C(N)=O)c(OCc5ccccc5)c4)cnc3c2)cn1 CHEMBL4063211 IC50 3.0 nM
C[C@@H](Oc1cc(-c2cnc3cc(-c4cnn(CCN(C)C)c4)ccn23)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL4860697 IC50 3.2 nM
CN(C)CCn1cc(-c2ccn3c(-c4ccc(C(N)=O)c(OCc5cccc(C(F)(F)F)c5)c4)cnc3c2)cn1 CHEMBL4091089 IC50 7.0 nM
C#Cc1nc(Nc2ccc3c(c2)C(=O)N(C)CC3)nc2[nH]cnc12 CHEMBL4763380 IC50 10.0 nM
C#Cc1nc(Nc2cccc(CS(=O)(=O)N(C)C)c2)nc2[nH]cnc12 CHEMBL4761747 IC50 10.0 nM
Nc1ncc(-c2cnn(CCO)c2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 CHEMBL1980297 pKi 12.59 nM
CNC(=O)C=Cc1cnc(N)c2c(-c3cc(F)c4[nH]c(C)cc4c3)csc12 CHEMBL2006778 pKi 12.59 nM
C#Cc1nc(Nc2cccc(CC(N)=O)c2)nc2[nH]cnc12 CHEMBL4786783 IC50 18.0 nM
COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC CHEMBL1241473 pKi 19.95 nM
Cc1nc[nH]c1/C=C1\C(=O)Nc2ccc(C(=O)CCl)cc21 CHEMBL1802383 IC50 20.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OC4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1794070 IC50 21.0 nM
C[C@H](/C=C\C(F)(F)F)Oc1cc(-c2cc(-c3cc(CN(C)C)cs3)cnc2N)ccc1C(N)=O CHEMBL2042135 IC50 22.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OC4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1615278 IC50 25.0 nM
C#Cc1nc(Nc2cccc(C(=O)NC)c2)nc2[nH]cnc12 CHEMBL4796125 IC50 26.0 nM
Cc1cc(=O)n2ccc(CN(C)C)c(O)c2n1 CHEMBL1988581 pKi 31.62 nM
C[C@@H](Oc1cc(-c2cc(-c3cc(CN(C)C)cs3)cnc2N)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL2042136 IC50 37.0 nM
C#Cc1nc(Nc2cccc(NC(C)=O)c2)nc2[nH]cnc12 CHEMBL4743876 IC50 39.0 nM
CCN1CCN(c2ccc(Nc3nccc(-c4c(-c5cccc(C(=O)Nc6ccccc6F)c5)nc5ccccn45)n3)cc2)CC1 CHEMBL1981725 pKi 39.81 nM
Cc1cc2cc(-c3csc4c(-c5cccc(S(C)(=O)=O)c5)cnc(N)c34)ccc2[nH]1 CHEMBL1997822 pKi 39.81 nM
C#Cc1nc(Nc2ccc3c(c2)CN(C)C(=O)C3)nc2[nH]cnc12 CHEMBL4779487 IC50 42.0 nM
CC(Oc1cc(-c2cc(-c3ccc(CN(C)C)s3)cnc2N)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL2042035 IC50 47.0 nM
Cc1cc(-c2cnc(N)c(-c3ccc(C(N)=O)c(OC(C)c4ccccc4C(F)(F)F)c3)c2)sc1CN(C)C CHEMBL2042036 IC50 47.0 nM
CC(Oc1cc(-n2cnc3ccc(OC4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1689158 IC50 50.0 nM
C#Cc1nc(Nc2cccc(C(=O)N(C)C)c2)nc2[nH]cnc12 CHEMBL4775990 IC50 50.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C[C@H](C)O)c5)cnc(N)c34)cc2)c1 CHEMBL3646210 IC50 50.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(CC(C)O)c5)cnc(N)c34)cc2)c1 CHEMBL1989708 pKi 50.12 nM
C#Cc1nc(Nc2ccc(CC(=O)N(C)C)cc2)nc2[nH]cnc12 CHEMBL4796754 IC50 57.0 nM
C#Cc1nc(Nc2cccc(CS(C)(=O)=O)c2)nc2[nH]cnc12 CHEMBL4783060 IC50 57.0 nM
Cc1cc(CN(C)C)sc1-c1cnc(N)c(-c2ccc(C(N)=O)c(OC(C)c3ccccc3C(F)(F)F)c2)c1 CHEMBL2042037 IC50 58.0 nM
CC(Oc1cc(-c2cc(-c3cc(CN(C)C)cs3)cnc2N)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL2042040 IC50 59.0 nM
O=C1Nc2ccc(C(=O)CCl)cc2/C1=C/c1cnc[nH]1 CHEMBL1802382 IC50 60.0 nM
Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1 CHEMBL1970317 pKi 63.1 nM
NC(=O)c1ccc2nc(-c3ccc([N+](=O)[O-])o3)cn2c1 CHEMBL1973359 pKi 63.1 nM
CNC(=O)C(C)n1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5ccc(C)cc5)cc4)csc23)cn1 CHEMBL1970142 pKi 63.1 nM
CC(O)Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1 CHEMBL2002165 pKi 63.1 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C)c5)cnc(N)c34)cc2)c1 CHEMBL1967116 pKi 63.1 nM
C#Cc1nc(Nc2ccc(C(=O)N(C)C)cc2)nc2[nH]cnc12 CHEMBL4748191 IC50 64.0 nM
C#Cc1nc(Nc2ccc(C(C(=O)NC)C(=O)NC)cc2)nc2[nH]cnc12 CHEMBL4795738 IC50 71.0 nM
C#Cc1nc(Nc2ccc(CC(=O)NC)cc2)nc2[nH]cnc12 CHEMBL4746054 IC50 72.0 nM
CC(/C=C\C(F)(F)F)Oc1cc(-c2cc(-c3cc(CN(C)C)cs3)cnc2N)ccc1C(N)=O CHEMBL2042041 IC50 73.0 nM
C#Cc1nc(Nc2cccc(CC(=O)NC)c2)nc2[nH]cnc12 CHEMBL4783265 IC50 76.0 nM
C#Cc1nc(Nc2cccc(CC(C)=O)c2)nc2[nH]cnc12 CHEMBL4776787 IC50 76.0 nM
C#Cc1nc(Nc2cccc(CCC(N)=O)c2)nc2[nH]cnc12 CHEMBL4746829 IC50 79.0 nM
Cc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C)c5)cnc(N)c34)cc2)cc1 CHEMBL1982466 pKi 79.43 nM
CN(C)CCn1cc(-c2ccn3c(-c4ccc(C(N)=O)c(OCc5ccccc5F)c4)cnc3c2)cn1 CHEMBL4087758 IC50 87.0 nM
C#Cc1nc(Nc2cccc(CC(=O)N(C)C)c2)nc2[nH]cnc12 CHEMBL4761123 IC50 88.0 nM
CC(Oc1cc(-c2cc(-c3ccc(CN4CCCCC4)s3)cnc2N)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL2042038 IC50 93.0 nM
C#Cc1nc(Nc2ccc(CC(N)=O)cc2)nc2[nH]cnc12 CHEMBL4776060 IC50 93.0 nM
CNCC#Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12 CHEMBL1964441 pKi 100.0 nM
CC(C)(C(N)=O)n1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1 CHEMBL1967720 pKi 100.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3coc4c(C#CCN5CCOCC5)cnc(N)c34)cc2)c1 CHEMBL1983640 pKi 100.0 nM
C#Cc1nc(Nc2ccc3c(c2)CC(=O)N3)nc2[nH]cnc12 CHEMBL4754015 IC50 100.0 nM
CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CHEMBL386051 Kd 110.0 nM
C#Cc1nc(Nc2ccc(C(N)=O)cc2)nc2[nH]cnc12 CHEMBL4753609 IC50 110.0 nM
C#Cc1nc(Nc2ccc(C(=O)NC)cc2)nc2[nH]cnc12 CHEMBL4756141 IC50 110.0 nM
C#Cc1nc(Nc2cccc(C(N)=O)c2)nc2[nH]cnc12 CHEMBL4759854 IC50 116.0 nM
CC(Oc1cc(-c2cc(-c3ccc(CN(C)C)cc3)cnc2N)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL2042031 IC50 120.0 nM
Nc1ncc(-c2cnn(CCO)c2)c2scc(-c3ccc(NC(=O)Nc4ccc(OC(F)F)cc4)cc3)c12 CHEMBL1972220 pKi 125.89 nM
O=C(Nc1ccc([N+](=O)[O-])cc1)N1CCc2[nH]c3c(Cl)cc(Cl)cc3c2C1 CHEMBL1976196 pKi 125.89 nM
CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl CHEMBL1993661 pKi 125.89 nM
CCCn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1 CHEMBL1993941 pKi 125.89 nM
CN1c2ccc(N)cc2C(c2ccccc2)c2cc(N)ccc21 CHEMBL1991734 pKi 125.89 nM
CCN(CC)CCNC(=O)C=Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12 CHEMBL2004716 pKi 125.89 nM
CCc1nc(C)c(/C=C2\C(=O)Nc3ccc(C(=O)CCl)cc32)[nH]1 CHEMBL1802384 IC50 130.0 nM
C#Cc1nc(Nc2cccc(CS(N)(=O)=O)c2)nc2[nH]cnc12 CHEMBL4754958 IC50 130.0 nM
CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)/C=C/CN(C)C CHEMBL607707 Kd 140.0 nM
C#Cc1nc(Nc2ccccc2)nc2[nH]cnc12 CHEMBL4094562 IC50 140.0 nM
C#Cc1nc(Nc2ccc(S(N)(=O)=O)cc2)nc2[nH]cnc12 CHEMBL4074015 IC50 140.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(CN4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1908394 IC50 158.0 nM
COCCOC1CCC(n2nc(-c3ccc(Nc4nc5cc(C)cc(C)c5o4)cc3)c3c(N)ncnc32)CC1 CHEMBL1984162 pKi 158.49 nM
CCNC(=O)c1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)csc12 CHEMBL1979516 pKi 158.49 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 170.0 nM
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC CHEMBL475251 pKi 199.53 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cn[nH]c5)cnc(N)c34)cc2)c1 CHEMBL1969102 pKi 199.53 nM
COc1cc(-c2nn(C3CCC(N4CCN(C(C)=O)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C CHEMBL1970879 pKi 199.53 nM
Cc1ccc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1 CHEMBL1988075 pKi 199.53 nM
N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 CHEMBL1987034 pKi 199.53 nM
Cc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C(C)C(=O)N(C)C)c5)cnc(N)c34)cc2)cc1 CHEMBL2001485 pKi 199.53 nM
COc1ccc(C2=NNc3cccc4c(OC)ccc2c34)cc1OC CHEMBL1997335 pKi 199.53 nM
CNC(=O)c1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)csc12 CHEMBL1982476 pKi 199.53 nM
COc1cc(-c2cnc(N)c(N3CC[C@@H](C(=O)O)[C@@H](C)[C@H]3C)n2)cc(OC)c1OC CHEMBL1276848 IC50 200.0 nM
CC(Oc1cc(-c2cc(-c3cccc(CN(C)C)c3)cnc2N)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL2042032 IC50 210.0 nM
C#Cc1nc(Nc2cccc(C(C)(C)C(N)=O)c2)nc2[nH]cnc12 CHEMBL4751371 IC50 210.0 nM
CC(Oc1cc(-n2cnc3cc(OC4CCN(C)CC4)ccc32)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1689165 IC50 230.0 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(OC)c2)nc1NC1CCOCC1 CHEMBL3301622 Kd apparent 247.0 nM
CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)/C=C/CN(C)C CHEMBL180022 Kd 250.0 nM
O=C(Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCCC4=O)c3)n2)c1)c1c(F)cccc1F CHEMBL2006715 pKi 251.19 nM
N#CC1=C(c2ccccc2)CC(c2ccc(Cl)cc2)C(C(=O)c2ccccc2)C1=O CHEMBL1978371 pKi 251.19 nM
CNc1nc(C)c(-c2ccnc(Nc3ccc(N4CCNCC4)cc3)n2)s1 CHEMBL1999484 pKi 251.19 nM
COC(=O)c1c(-c2ccc(NC(=O)Nc3ccccc3)cc2)c2c(N)ncnn2c1C CHEMBL1977041 pKi 251.19 nM
CCn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(OC(F)(F)F)c2)c2c(N)ncnc21 CHEMBL4281823 IC50 268.0 nM
CN(C)CCCNC(=O)Cc1cccc(Nc2nc(OCC3CCCCC3)c3nc[nH]c3n2)c1 CHEMBL5283398 IC50 280.0 nM
O=C(Cc1ccccc1)Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCOCC4)c3)n2)c1 CHEMBL1090360 IC50 310.0 nM
COc1cc(-c2csc3c(C=CC(=O)NCCN(C)C)cnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C CHEMBL1989267 pKi 316.23 nM
COc1c(-c2nc3ccccc3[nH]2)c(O)cc2oc(C)cc(=O)c12 CHEMBL1972355 pKi 316.23 nM
CCNc1nc(C)c(-c2ccnc(Nc3ccc(N4CCN(C(C)=O)CC4)cc3)n2)s1 CHEMBL1983715 pKi 316.23 nM
Cc1cccc(Nc2nccc(Nc3c(NC(C)C(C)(C)C)c(=O)c3=O)n2)c1 CHEMBL1969523 pKi 316.23 nM
COCCOC1CCC(n2nc(-c3ccc(Nc4nc5cc(C)cc(Cl)c5o4)cc3)c3c(N)ncnc32)CC1 CHEMBL1987054 pKi 316.23 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCNS(C)(=O)=O)cnc(N)c34)cc2)c1 CHEMBL1994321 pKi 316.23 nM
Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5ccc(OC(F)F)cc5)cc4)csc23)cn1 CHEMBL1988387 pKi 316.23 nM
CC(Oc1cc(-c2cc(-c3ccc(CN4CCOCC4)s3)cnc2N)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL2042039 IC50 318.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(OC4CCN(C)CC4)ccc32)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1615277 IC50 360.0 nM
CC(Oc1cc(-n2cnc3cc(OCCCN(C)C)ccc32)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1689168 IC50 380.0 nM
CN(C)CCn1cc(-c2ccn3c(-c4ccc(C(N)=O)c(OCc5ccc(C(F)(F)F)cc5)c4)cnc3c2)cn1 CHEMBL4105643 IC50 386.0 nM
COc1cc(-c2cnc(N)c(N3CC[C@@H](C(=O)O)[C@@H](C)C3)n2)cc(OC)c1OC CHEMBL1277755 IC50 390.0 nM
C#CC(=O)Nc1ccc2c(c1)/C(=C/c1[nH]cnc1C)C(=O)N2 CHEMBL1802869 IC50 390.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN(C)C)cnc(N)c34)cc2)c1 CHEMBL1979883 pKi 398.11 nM
Cc1cc(C)cc(NC(=O)Nc2ccc(-c3c(C)sc4ncnc(N)c34)cc2)c1 CHEMBL371206 pKi 398.11 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN5CCOCC5)cnc(N)c34)cc2)c1 CHEMBL1982465 pKi 398.11 nM
CNC(=O)c1cnc(N)c2c(-c3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)csc12 CHEMBL2005631 pKi 398.11 nM
O=C(Cc1ccccc1)Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)c1 CHEMBL1090356 pKi 398.11 nM
Cc1ccc(Nc2nccc(N(C)c3ccc4c(C)n(C)nc4c3)n2)cc1S(N)(=O)=O CHEMBL477772 pKi 398.11 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN5CCCC5)cnc(N)c34)cc2)c1 CHEMBL1973211 pKi 398.11 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCCCCCCCCN)cnc(N)c34)cc2)c1 CHEMBL1978166 pKi 398.11 nM
COc1cc(-c2cnc(N)c(N3CCC(C(=O)O)CC3)n2)cc(OC)c1OC CHEMBL1231522 IC50 410.0 nM
COc1cccc(C2=C(Nc3ccc(Cl)c(C(=O)O)c3)C(=O)NC2=O)c1 CHEMBL349810 Kd 460.0 nM
CN(C)CCn1cc(-c2ccn3c(-c4ccc(C(N)=O)c(OCc5ccccc5C(F)(F)F)c4)cnc3c2)cn1 CHEMBL4101298 IC50 478.0 nM
N#Cc1ccc(-c2cnc3[nH]cc(NC(=O)c4cccnc4)c3c2)cc1 CHEMBL516312 Kd 483.0 nM
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C CHEMBL535 Kd 500.0 nM
CCC(=O)Nc1ccc(C(=O)N2CCNCC2)c(O)c1 CHEMBL1988141 pKi 501.19 nM
CC(=NNC(=N)N)c1cc(NC(=O)c2cccc(C(=O)Nc3cc(C(C)=NNC(=N)N)cc(C(C)=NNC(=N)N)c3)c2)cc(C(C)=NNC(=N)N)c1 CHEMBL2000685 pKi 501.19 nM
Cc1ccc(NC(=O)Nc2ccc(-c3csc4ncnc(N)c34)cc2)cc1C CHEMBL2000335 pKi 501.19 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CC(C)(C)N)cnc(N)c34)cc2)c1 CHEMBL1979577 pKi 501.19 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(N)=O)s3)c2cc1OC CHEMBL514499 pKi 501.19 nM
O=C1CCCN1Cc1ccc2c(c1)[nH]c(=O)c1cccn12 CHEMBL539474 pKi 501.19 nM
O=C(Cc1ccccc1)Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCCC4=O)c3)n2)c1 CHEMBL1991429 pKi 501.19 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cnc4c(-c5cnn(C)c5)cnn4c3N)cc2)c1 CHEMBL508928 pKi 501.19 nM
CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CHEMBL522892 pKi 501.19 nM
C[C@@H](Oc1cc(-c2cnc3cc(OC4CCN(C)CC4)ccn23)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL4062949 IC50 591.0 nM
Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1C(=O)N1CCC[C@@H]1CN1CCCC1 CHEMBL450786 Kd 600.0 nM
C#CC(=O)Nc1ccc2c(c1)/C(=C/c1cnc[nH]1)C(=O)N2 CHEMBL1802388 IC50 620.0 nM
O=C(NNC(=S)Nc1ccc(F)cc1)C(O)(c1ccccc1)c1ccccc1 CHEMBL1975138 pKi 630.96 nM
CNc1ncnc2c1N=C(c1ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc1)CCN2 CHEMBL1981410 pKi 630.96 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4ncnc(N)c34)cc2)c1 CHEMBL196363 pKi 630.96 nM
CCC(N)(C#Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12)CC CHEMBL1983025 pKi 630.96 nM
Nc1ncnc2scc(-c3ccc(NC(=O)Nc4ccccc4)cc3)c12 CHEMBL1967531 pKi 630.96 nM
O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 CHEMBL1973540 pKi 630.96 nM
Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CHEMBL1967878 pKi 630.96 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(=O)O)s3)c2cc1OC CHEMBL474432 pKi 630.96 nM
O=C1NCCc2[nH]c(-c3ccnc(C=Cc4ccccc4)c3)cc21 CHEMBL1997129 pKi 630.96 nM
O=C(NNC(=S)Nc1ccc(Cl)cc1)C(O)(c1ccccc1)c1ccccc1 CHEMBL1966722 pKi 630.96 nM
COc1ccc(Nc2nccc(Nc3c(NC(C)C(C)(C)C)c(=O)c3=O)n2)cc1OC CHEMBL1964399 pKi 630.96 nM
CC(Oc1cc(-n2cnc3ccc(OC4CCN(C)CC4)cc32)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1689164 IC50 660.0 nM
COc1cc(-c2cnc(N)c(-c3ccc(C(=O)O)cc3)n2)cc(OC)c1OC CHEMBL1236145 IC50 710.0 nM
CCc1ccsc1-c1cnc(N)c(N2CCC(C(=O)O)CC2)n1 CHEMBL1277019 IC50 720.0 nM
C#CC(=O)Nc1ccc2c(c1)/C(=C/c1[nH]c(CC)nc1C)C(=O)N2 CHEMBL1802870 IC50 770.0 nM
CC(Oc1cc(-c2nc(-c3ccc(CN(C)C)cc3)cnc2N)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL2042029 IC50 790.0 nM
CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CHEMBL1983111 pKi 794.33 nM
CN(Cc1cc(Cl)c(O)c2ncccc12)C1CCCCC1 CHEMBL1982413 pKi 794.33 nM
COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL509032 pKi 794.33 nM
Oc1ccc2nc(-c3ccc(Sc4ccc(-c5nc6ccc(O)cc6[nH]5)cc4)cc3)[nH]c2c1 CHEMBL2001149 pKi 794.33 nM
Nc1ncc(-c2ccoc2)c2scc(-c3ccc(NC(=O)Nc4ccccc4F)cc3)c12 CHEMBL1965570 pKi 794.33 nM
CC(=O)N1CCN(C2CCC(n3nc(-c4ccc(NC(=O)c5cc6ccccc6n5C)cc4)c4c(N)ncnc43)CC2)CC1 CHEMBL1972584 pKi 794.33 nM
Nc1ncc(-c2ccncc2)c2scc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL1970083 pKi 794.33 nM
O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 CHEMBL244378 pKi 794.33 nM
C=CCn1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2n1-c1cccc(C(C)(C)O)n1 CHEMBL1976040 pKi 794.33 nM
Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 CHEMBL482967 pKi 794.33 nM
CN1CCC(Oc2ccn3c(-c4ccc(C(N)=O)c(OCc5ccccc5)c4)cnc3c2)CC1 CHEMBL4065063 IC50 808.0 nM
C#Cc1nc(Nc2cccc3c2NC(=O)C3)nc2[nH]cnc12 CHEMBL4785527 IC50 820.0 nM
CN1CCC(Oc2ccn3c(-c4ccc(C(N)=O)c(OCc5ccccc5C(F)(F)F)c4)cnc3c2)CC1 CHEMBL4102393 IC50 838.0 nM
C#CC(=O)Nc1ccc2c(c1)/C(=C/c1ccc[nH]1)C(=O)N2 CHEMBL1802387 IC50 920.0 nM
C[C@@H](Oc1cc(-c2cnc3cc(-c4cnn(CCN(C)C)c4)ccn23)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL4083300 IC50 927.0 nM
Cn1cc(-c2cnc3c(-c4csc(C(=O)N[C@@H]5CCCC[C@@H]5N)c4)cnn3c2)cn1 CHEMBL4568087 IC50 950.0 nM
NC(=O)c1cccc(-c2cnc3[nH]cc(-c4ccccc4)c3c2)c1 CHEMBL1982957 pKi 1000.0 nM
COc1cccc(OC)c1CNc1nc(NC2CCCCC2)nc2ccc(Cl)cc12 CHEMBL1996646 pKi 1000.0 nM
COc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(CC(O)CO)c5)cnc(N)c34)cc2)cc1 CHEMBL1965170 pKi 1000.0 nM
Nc1ncnc2c1N=C(c1ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc1)CCN2 CHEMBL260092 pKi 1000.0 nM
Nc1ncnc2onc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c12 CHEMBL213505 pKi 1000.0 nM
CCn1c(C)c(-c2ccnc(Nc3cccc(OC)c3)n2)sc1=O CHEMBL1986263 pKi 1000.0 nM
COc1cc(Nc2ncnc(N3CCCc4cc(C)ccc43)n2)cc(OC)c1OC CHEMBL1992125 pKi 1000.0 nM
O=C(Cc1cccs1)Nc1nc2ccccc2s1 CHEMBL1421720 pKi 1000.0 nM
CNC(=O)C=Cc1cnc(N)c2c(-c3ccc4c(c3)OCO4)csc12 CHEMBL1993243 pKi 1000.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3nsc4ncnc(N)c34)cc2)c1 CHEMBL262433 pKi 1000.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN)cnc(N)c34)cc2)c1 CHEMBL1965988 pKi 1000.0 nM
Cn1nc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)cncc21 CHEMBL1964692 pKi 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM