Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(-c2ccnc(N3CCN(C)CC3)c2)cc1Cl CHEMBL3357688 Ki 0.9 nM
Cc1c(NS(=O)(=O)c2ccc(-c3ccc4c(c3)CN(C)CCC4)cc2)c(CC(C)C)nn1C CHEMBL4115136 IC50 2.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl CHEMBL1230468 IC50 3.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2ccnc(N3CCNCC3)c2)cc1Cl CHEMBL4111551 IC50 3.0 nM
Cc1c(NS(=O)(=O)c2c(Cl)cc(-c3ccnc(N4CCNCC4)c3)cc2Cl)c(CC(C)C)nn1C CHEMBL3357685 IC50 3.0 nM
CCN(c1c(C)nn(C)c1C)S(=O)(=O)c1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl CHEMBL3980411 IC50 3.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(CCCCC2CCN(C)CC2)cc1Cl CHEMBL3357697 IC50 4.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl CHEMBL3357702 IC50 4.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCCC2CCNCC2)cc1Cl CHEMBL3358119 IC50 4.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl CHEMBL3920615 IC50 4.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3ccc4c(c3)CNCCC4)cc2)c(CC(C)C)nn1C CHEMBL4110040 IC50 4.0 nM
Cc1nn(C)c(C)c1Cc1nnc(-c2cc(Cl)ccc2OC2CCNCC2)o1 CHEMBL3770219 Ki 4.8 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(CCCCC2CCNCC2)cc1Cl CHEMBL3357699 IC50 5.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCCC2CCN(C)CC2)cc1Cl CHEMBL3358120 IC50 5.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCOC2CCN(C)CC2)cc1Cl CHEMBL3358121 IC50 5.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2cccc(CC3CCN(C)CC3)c2)cc1 CHEMBL4106967 IC50 5.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1c(Cl)cc(-c2cccc(CN3CCN(C)CC3)c2)cc1Cl CHEMBL3911634 IC50 5.0 nM
Cc1cc(-c2ccnc(N3CCNCC3)c2)ccc1S(=O)(=O)Nc1c(C)nn(C)c1C CHEMBL4109103 IC50 6.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CNCCc4cccnc4)c3)cc2)c(CC(C)C)nn1C CHEMBL4113504 IC50 6.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(-c2cccc(CN3CCN(C)CC3)c2)cc1Cl CHEMBL1951295 IC50 7.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2ccnc(N3CCNCC3)c2)cc1 CHEMBL4112331 IC50 7.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCN2CCCN(C)CC2)cc1Cl CHEMBL3894086 IC50 7.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl CHEMBL3357695 IC50 8.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCCCCN(C)C)cc1Cl CHEMBL3358122 IC50 8.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2cccc(CN3CCN(C)CC3)c2)cc1 CHEMBL3357704 IC50 8.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2ccnc(N3CCNC(C)C3)c2)cc1 CHEMBL4107350 IC50 8.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2ccnc(N3CCCNCC3)c2)cc1 CHEMBL4113507 IC50 8.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCN2CCCNCC2)cc1Cl CHEMBL3956897 IC50 8.0 nM
CCOC(=O)c1cnc2ccc(OCc3ccc(NCCCN)nc3)cc2c1SCC CHEMBL4176755 Ki(app) 8.0 nM
Cc1c(NS(=O)(=O)c2c(Cl)cc(-c3ccnc(N4CCNCC4)c3)cc2Cl)cnn1C CHEMBL3357681 IC50 9.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl CHEMBL3358117 IC50 9.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2ccnc(N3CCNCC3)c2)cc1F CHEMBL4107928 IC50 9.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1ccc(-c2cccc(CC3CCN(C)CC3)c2)cc1 CHEMBL3933235 IC50 9.0 nM
CCN(c1c(C)nn(C)c1C)S(=O)(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl CHEMBL3946900 IC50 9.0 nM
Cc1nn(C)cc1NS(=O)(=O)c1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl CHEMBL3357682 IC50 10.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(N2CCCC(N3CCNCC3)C2)nc1 CHEMBL1951287 IC50 10.0 nM
Cc1c(NS(=O)(=O)c2c(Cl)cc(CCCC3CCNCC3)cc2Cl)c(CC(C)C)nn1C CHEMBL4106516 IC50 10.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3ccc(Cl)c(CN(C)C)c3)cc2)c(CC(C)C)nn1C CHEMBL4114439 IC50 10.0 nM
Cc1ncccc1COc1cc(F)c(-c2ccnc(N3CCNCC3)c2)cc1F CHEMBL4080376 IC50 10.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1c(Cl)cc(CCCN2CCCNCC2)cc1Cl CHEMBL3949096 IC50 11.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3ccc(F)c(CN(C)C)c3)cc2)c(CC(C)C)nn1C CHEMBL4112060 IC50 11.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3ccc4c(c3)CNCC4)cc2)c(CC(C)C)nn1C CHEMBL4111502 IC50 11.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCC2CCN(C)CC2)cc1Cl CHEMBL3358114 IC50 12.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1ccc(-c2ccnc(N3CCNCC3)c2)cc1 CHEMBL3937813 IC50 12.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1cc(F)c(-c2ccnc(N3CCNCC3)c2)cc1F CHEMBL4115156 IC50 13.0 nM
Cc1ccc(-c2ccc(S(=O)(=O)Nc3c(CC(C)C)nn(C)c3C)cc2)cc1CN(C)C CHEMBL4112733 IC50 13.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CN(C)C)c3)cc2)c(CC(C)C)nn1C CHEMBL3913730 IC50 14.0 nM
Cc1cncn1C(C)C(=O)NCc1cccnc1C1CCCN(C)CC1 CHEMBL4435880 Ki 14.5 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(-c2cccc(N3CCNCC3)c2)cc1Cl CHEMBL3357686 IC50 16.0 nM
Cc1c(NS(=O)(=O)c2c(Cl)cc(CCCC3CCN(C)CC3)cc2Cl)c(CC(C)C)nn1C CHEMBL4108774 IC50 16.0 nM
COc1ccccc1-n1cc(-c2ccnc(NCCC3CCCN3C)n2)cn1 CHEMBL4449105 Ki 16.7 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1ccc(-c2cccc(CN3CCN(C)CC3)c2)cc1 CHEMBL3357705 IC50 17.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CN(C)C)c3)c(C(F)(F)F)c2)c(CC(C)C)nn1C CHEMBL4114647 IC50 17.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCOC2CN3CCC2CC3)cc1Cl CHEMBL3958873 IC50 17.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1c(Cl)cc(CCCC2CCN(C)CC2)cc1Cl CHEMBL3358111 IC50 18.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(C(C)(C)N)c3)cc2)c(CC(C)C)nn1C CHEMBL4106956 IC50 18.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl CHEMBL3958400 IC50 18.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1c(Cl)cc(CCCN2CCN3CCC[C@@H]3C2)cc1Cl CHEMBL4532268 Ki 18.0 nM
Cc1nn(C)c(C)c1N(CC(F)F)S(=O)(=O)c1ccc(-c2ccnc(N3CCNCC3)c2)cc1 CHEMBL3983158 IC50 19.0 nM
CNCc1cccc(-c2ccc(S(=O)(=O)Nc3c(CC(C)C)nn(C)c3C)cc2)c1 CHEMBL4113854 IC50 19.0 nM
Cc1c(N(C(F)F)S(=O)(=O)c2c(Cl)cc(-c3ccnc(N4CCNCC4)c3)cc2Cl)c(CC(C)C)nn1C CHEMBL3965395 IC50 19.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CN(C)C)c3)cc2)c(CC2CC2)nn1C CHEMBL3922714 IC50 19.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1c(Cl)cc(CCCN2CCNCC2)cc1Cl CHEMBL3912318 Ki 19.1 nM
Cc1nccn1CCCCc1ccc([C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC2CCCCC2)cc1 CHEMBL291791 IC50 19.98 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(-c2cccc(C3CCNCC3)c2)cc1Cl CHEMBL3357687 IC50 20.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1ccc(-c2ccnc(N3CCNCC3)c2)cc1 CHEMBL3357703 IC50 20.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3ccc4c(c3)CN(C)CC4)cc2)c(CC(C)C)nn1C CHEMBL4112881 IC50 20.0 nM
Cc1nn(C)c(C)c1N(CC(F)(F)F)S(=O)(=O)c1ccc(-c2ccnc(N3CCNCC3)c2)cc1 CHEMBL3954901 IC50 21.0 nM
CCN(C)Cc1cccc(-c2ccc(S(=O)(=O)Nc3c(CC(C)C)nn(C)c3C)cc2)c1 CHEMBL4109297 IC50 21.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1ccc(CCCCCCCCN(C)C)cc1 CHEMBL3976191 IC50 21.0 nM
CCCNCc1cccc(-c2ccc(S(=O)(=O)Nc3c(CC(C)C)nn(C)c3C)cc2)c1 CHEMBL4112803 IC50 21.0 nM
CCNCc1cccc(-c2ccc(S(=O)(=O)Nc3c(CC(C)C)nn(C)c3C)cc2)c1 CHEMBL4109755 IC50 22.0 nM
COc1cccc(-n2cc(-c3ccnc(NCCC4CCCN4C)n3)cn2)c1 CHEMBL4470652 Ki 23.8 nM
CCN(c1c(C)nn(C)c1C)S(=O)(=O)c1c(Cl)cc(CCCC2CCN(C)CC2)cc1Cl CHEMBL3358113 IC50 24.0 nM
c1cnc(OC2CCNCC2)c(-c2nc(Cc3cccc4ncccc34)no2)c1 CHEMBL3754571 Ki(app) 24.0 nM
Cc1nn(C)c(CC(C)C)c1NS(=O)(=O)c1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl CHEMBL3357684 IC50 25.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CC4CCNCC4)c3)cc2)c(CC(C)C)nn1C CHEMBL4106819 IC50 25.0 nM
N[C@@H](CC(=O)N1C[C@H](CO)[C@@H](c2ccc(Cl)c(NC(=O)Cc3ccc(F)cc3)c2)C1)Cc1ccc(Cl)cc1 CHEMBL3357975 Ki 27.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(CCCCC2CCNCC2)cc1 CHEMBL3357700 IC50 29.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cc(CN(C)C)ccc3F)cc2)c(CC(C)C)nn1C CHEMBL4107201 IC50 29.0 nM
N[C@@H](CC(=O)N1C[C@H](CO)[C@@H](c2ccc(Cl)cc2)C1)Cc1ccc(Cl)cc1 CHEMBL3344387 Ki 29.2 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(C(C)(C)N4CCCC4)c3)cc2)c(CC(C)C)nn1C CHEMBL3924504 IC50 30.0 nM
Cc1nc(C)c(COc2c(Cl)cc(-c3ccnc(N4CCNCC4)c3)cc2Cl)o1 CHEMBL4071314 IC50 30.0 nM
Cc1ncccc1COc1cc(F)c(-c2ccnc(N3CCNCC3)c2)c(F)c1 CHEMBL4069661 IC50 30.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(CCCCC2CCN(C)CC2)cc1 CHEMBL3357698 IC50 32.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(CCCC2CCN(C)CC2)cc1Cl CHEMBL3357693 IC50 33.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CN(C)C)c3)c(Cl)c2)c(CC(C)C)nn1C CHEMBL4109674 IC50 33.0 nM
Cc1nn(C)c(C)c1N(CC(F)F)S(=O)(=O)c1c(Cl)cc(CCCCC2CCNCC2)cc1Cl CHEMBL3954455 IC50 33.0 nM
COc1cccc(Cc2noc(-c3ccccc3OC3CCNCC3)n2)c1 CHEMBL3754110 Ki 33.0 nM
Cc1nn(C)c(C)c1N(CC(F)F)S(=O)(=O)c1c(Cl)cc(CCCOC2CCN(C)CC2)cc1Cl CHEMBL3904089 IC50 34.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1ccc(CCCCCCCN(C)C)cc1 CHEMBL3985307 IC50 36.0 nM
Cc1c(N(C)S(=O)(=O)c2ccc(-c3ccc4c(c3)CNCC4)cc2)c(CC(C)C)nn1C CHEMBL3959131 IC50 37.0 nM
CCCc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2cccc(CN(C)C)c2)cc1 CHEMBL4110139 IC50 39.0 nM
Cc1nccn1CCCCc1ccc(C(C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC2CCCCC2)cc1 CHEMBL188653 IC50 40.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2ccnc(N3CC(C)NC(C)C3)c2)cc1 CHEMBL4114130 IC50 40.0 nM
CCCc1ncccc1COc1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl CHEMBL4096886 IC50 40.0 nM
CC(C)Cc1ncccc1COc1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl CHEMBL4104613 IC50 40.0 nM
Clc1cc(-c2ccnc(N3CCNCC3)c2)cc(Cl)c1OCc1cccnc1N1CCOCC1 CHEMBL4080389 IC50 40.0 nM
CCOC(=O)c1cnc2ccc(OCc3ccc(N4CCNCC4)nc3)cc2c1SCC CHEMBL4172452 Ki(app) 40.0 nM
Cc1cc(S(=O)(=O)Nc2c(CC(C)C)nn(C)c2C)ccc1-c1cccc(CN(C)C)c1 CHEMBL4111385 IC50 41.0 nM
CCC(C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC1CCCCC1)c1ccc(CCCCn2ccnc2C)cc1 CHEMBL59835 IC50 42.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCCCCn2ccnc2C)cc1Cl CHEMBL3896984 IC50 42.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCOC[C@H]2CCCN2C)cc1Cl CHEMBL3358125 IC50 45.0 nM
Cc1nn(C)c(C)c1N(CC(F)(F)F)S(=O)(=O)c1c(Cl)cc(CCCOC2CCN(C)CC2)cc1Cl CHEMBL3949901 IC50 46.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCN2CCN3CCC[C@@H]3C2)cc1Cl CHEMBL3358127 IC50 47.0 nM
CCN(CC)Cc1cccc(-c2ccc(S(=O)(=O)Nc3c(CC(C)C)nn(C)c3C)cc2)c1 CHEMBL4112329 IC50 47.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1ccc(-c2cccc(CC3CCNCC3)c2)cc1 CHEMBL3900805 IC50 47.0 nM
CCCCc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2cccc(CN(C)C)c2)cc1 CHEMBL4112269 IC50 47.0 nM
CCOC(=O)c1cnc2ccc(OCc3ccc(N[C@@H]4CCNC4)nc3)cc2c1SCC CHEMBL4173973 Ki(app) 50.0 nM
CCOC(=O)c1cnc2ccc(OCc3ccc(NCCN)nc3)cc2c1SCC CHEMBL4168895 Ki(app) 50.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(C(C)(C)N(C)C)c3)cc2)c(CC(C)C)nn1C CHEMBL4106694 IC50 51.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(CCCOC2CCN(C)CC2)cc1 CHEMBL4113477 IC50 52.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(C4CCNCC4)c3)cc2)c(CC(C)C)nn1C CHEMBL4107652 IC50 54.0 nM
Cc1c(NS(=O)(=O)c2ccc(CCCCC3CCNCC3)cc2)c(CC(C)C)nn1C CHEMBL4115578 IC50 56.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3ccc(F)c(CN4CCCC4)c3)cc2)c(CC(C)C)nn1C CHEMBL4110447 IC50 57.0 nM
CCN(CC)Cc1cccc(-c2ccc(S(=O)(=O)Nc3c(CC(C)C)nn(C)c3C)c(Cl)c2)c1 CHEMBL4114484 IC50 58.0 nM
Cn1cc(NS(=O)(=O)c2c(Cl)cc(-c3ccnc(N4CCNCC4)c3)cc2Cl)cn1 CHEMBL3357683 IC50 59.0 nM
Cc1nccn1CCCCc1ccc(CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC2CCCCC2)cc1 CHEMBL6269 IC50 60.0 nM
Cc1nn(C)c(C)c1N(CC(F)F)S(=O)(=O)c1c(Cl)cc(CCCCC2CCN(C)CC2)cc1Cl CHEMBL3908890 IC50 60.0 nM
Cc1ncccc1COc1ccc(-c2ccnc(N3CCNCC3)c2)c(F)c1 CHEMBL4096874 IC50 60.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CN4CCCC4C)c3)cc2)c(CC(C)C)nn1C CHEMBL4112245 IC50 61.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2cccc(CCN(C)C)c2)cc1 CHEMBL4109333 IC50 64.0 nM
COc1cccc(Cc2noc(-c3cc(Cl)ccc3OC3CCNCC3)n2)c1 CHEMBL3770442 Ki 70.0 nM
Cc1nn(C)c(C)c1N(CC(F)(F)F)S(=O)(=O)c1c(Cl)cc(CCCCC2CCNCC2)cc1Cl CHEMBL3932878 IC50 71.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCOC[C@@H]2CCCN2C)cc1Cl CHEMBL3358123 IC50 74.0 nM
Cc1nn(C)c(C)c1N(CC(F)(F)F)S(=O)(=O)c1ccc(-c2cccc(CN3CCN(C)CC3)c2)cc1 CHEMBL3946709 IC50 75.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1ccc(CCCCCCN(C)C)cc1 CHEMBL3936759 IC50 76.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CN4CCC4)c3)cc2)c(CC(C)C)nn1C CHEMBL4109216 IC50 76.0 nM
COCCNCc1cccc(-c2ccc(S(=O)(=O)Nc3c(CC(C)C)nn(C)c3C)cc2)c1 CHEMBL4114103 IC50 77.0 nM
Cc1ncccc1NS(=O)(=O)c1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl CHEMBL4108894 IC50 80.0 nM
Cc1nc(C)c(COc2c(Cl)cc(-c3ccnc(N4CCNCC4)c3)cc2Cl)s1 CHEMBL4090626 IC50 80.0 nM
Cc1cc(OCc2cccnc2C)ccc1-c1ccnc(N2CCNCC2)c1 CHEMBL4062072 IC50 80.0 nM
CCOC(=O)c1cnc2ccc(OCc3ccc(NC4CCNCC4)nc3)cc2c1SCC CHEMBL4163264 Ki(app) 80.0 nM
Cc1nn(C)c(C)c1N(CC(F)F)S(=O)(=O)c1c(Cl)cc(CCCN2CCCNCC2)cc1Cl CHEMBL3961187 IC50 81.0 nM
Cc1c(NS(=O)(=O)c2ccc(CCCC3CCNCC3)cc2)c(CC(C)C)nn1C CHEMBL4115133 IC50 88.0 nM
Cc1ncccc1COc1ccc(-c2ccnc(N3CCNCC3)c2)cc1 CHEMBL4099270 IC50 90.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cc(CN(C)C)ccc3Cl)cc2)c(CC(C)C)nn1C CHEMBL4110526 IC50 94.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CN(C)C)c3)cc2)c(CCc2ccccc2)nn1C CHEMBL4108150 IC50 96.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1ccc(-c2cccc(C3CCNCC3)c2)cc1 CHEMBL3898264 IC50 100.0 nM
Clc1cc(-c2ccnc(N3CCNCC3)c2)cc(Cl)c1OCc1cccnc1 CHEMBL4088228 IC50 100.0 nM
CCSc1c(C(=O)N2CCOCC2)cnc2ccc(OCc3ccccc3)cc12 CHEMBL4161807 Ki(app) 100.0 nM
Cc1nn(C)c(C)c1N(CC(F)F)S(=O)(=O)c1c(Cl)cc(CCCN2CCCN(C)CC2)cc1Cl CHEMBL3925688 IC50 101.0 nM
Cc1nn(C)c(C)c1N(CC(F)(F)F)S(=O)(=O)c1c(Cl)cc(CCCCC2CCN(C)CC2)cc1Cl CHEMBL3925632 IC50 110.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CN(C)C)c3)cc2)c(Cc2ccccc2)nn1C CHEMBL3936245 IC50 110.0 nM
CCN(CC)Cc1cccc(-c2cc(Cl)c(S(=O)(=O)Nc3c(C)nn(C)c3C)c(Cl)c2)c1 CHEMBL1951296 IC50 120.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CN4CCCC4)c3)cc2)c(CC(C)C)nn1C CHEMBL4114988 IC50 120.0 nM
Cc1c(NS(=O)(=O)c2ccc(CCCC3CCN(C)CC3)cc2)c(CC(C)C)nn1C CHEMBL4112765 IC50 120.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(CCCC2CCNCC2)cc1 CHEMBL3357696 IC50 127.0 nM
CCCC(C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC1CCCCC1)c1ccc(CCCCn2ccnc2C)cc1 CHEMBL291811 IC50 130.0 nM
Cc1nn(C)c(C)c1N(CC(F)(F)F)S(=O)(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl CHEMBL3901668 IC50 134.0 nM
CCCc1nn(C)c(C)c1NS(=O)(=O)c1ccc(CCCCC2CCN(C)CC2)cc1 CHEMBL3950436 IC50 140.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1c(Cl)cc(CCCN2CC(C)NC(C)C2)cc1Cl CHEMBL3927779 IC50 141.0 nM
CCN(CC)Cc1cccc(-c2ccc(S(=O)(=O)N(C)c3c(CC(C)C)nn(C)c3C)cc2)c1 CHEMBL3942746 IC50 144.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCN2CCN(C)CC2)cc1Cl CHEMBL3358118 IC50 145.0 nM
Cc1nn(C)c(C)c1N(CC(F)F)S(=O)(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl CHEMBL3979069 IC50 148.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCOC[C@H]2CCCCN2C)cc1Cl CHEMBL3358126 IC50 150.0 nM
CCc1nn(C)c(CC)c1N(C)S(=O)(=O)c1c(Cl)cc(CCCN2CCN(C)CC2)cc1Cl CHEMBL3952070 IC50 150.0 nM
Cc1c(NS(=O)(=O)c2ccc(CCCC3CCN(C)CC3)cc2)c(CC2CC2)nn1C CHEMBL3942893 IC50 150.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CN(C)C)c3F)cc2)c(CC(C)C)nn1C CHEMBL4111686 IC50 153.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1ccc(CCCC2CCNCC2)cc1 CHEMBL3917062 IC50 164.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1c(Cl)cc(CCCCCCn2ccnc2)cc1Cl CHEMBL3953146 IC50 168.0 nM
Cc1c(NS(=O)(=O)c2ccc(CCCOC3CCN(C)CC3)cc2)c(CC(C)C)nn1C CHEMBL4106634 IC50 168.0 nM
Cc1c(NS(=O)(=O)c2ccc(CCCCC3CCN(C)CC3)cc2)c(CC(C)C)nn1C CHEMBL4114458 IC50 173.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3ccccc3CN(C)C)cc2)c(CC(C)C)nn1C CHEMBL4111697 IC50 174.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(CCCC2CCN(C)CC2)cc1 CHEMBL3357694 IC50 175.0 nM
Cc1nn(C)c(C)c1N(CC(F)F)S(=O)(=O)c1c(Cl)cc(CCCC2CCN(C)CC2)cc1Cl CHEMBL3358115 IC50 180.0 nM
Cc1nn(C)c(C)c1Cc1noc(-c2cccnc2OC2CCN(C(C)C)CC2)n1 CHEMBL3753789 Ki(app) 180.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2cccc(CCN3CCN(C)CC3)c2)cc1 CHEMBL4107927 IC50 180.0 nM
Cc1c(NS(=O)(=O)c2c(Cl)cc(CCCN3CCN(C)CC3)cc2Cl)c(CC(C)C)nn1C CHEMBL4112252 IC50 180.0 nM
CC(C)CCc1ncccc1COc1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl CHEMBL4061001 IC50 180.0 nM
CCN(C)c1nc(N(C)C2CCN(C)C2)nc2ccc(S(=O)(=O)Nc3c(C)nn(C)c3C)cc12 CHEMBL4647500 IC50 180.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1c(Cl)cc(CCCN2CCN(C)CC2)cc1Cl CHEMBL3357706 IC50 188.0 nM
Cc1c(N(C)S(=O)(=O)c2ccc(-c3cccc(C4CCNCC4)c3)cc2)c(CC(C)C)nn1C CHEMBL3903782 IC50 190.0 nM
Cc1nn(C)c(C)c1Cc1noc(-c2cccnc2OC2CCNCC2)n1 CHEMBL3752766 Ki(app) 200.0 nM
CC(C)c1nn(C)c(C(C)C)c1NS(=O)(=O)c1ccc(-c2cccc(CN(C)C)c2)cc1 CHEMBL3969027 IC50 200.0 nM
Clc1cc(-c2ccnc(N3CCNCC3)c2)cc(Cl)c1OCc1cccnc1-c1ccccc1 CHEMBL4069679 IC50 200.0 nM
Cc1ccnc(C)c1COc1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl CHEMBL4081852 IC50 200.0 nM
Cc1nn(C)c(C)c1N(CC(F)(F)F)S(=O)(=O)C1=C(Cl)C=C(CCCN2CCCNCC2)CC1Cl CHEMBL3978785 IC50 210.0 nM
Cc1nn(C)c(C)c1N(CC(F)(F)F)S(=O)(=O)c1c(Cl)cc(CCCN2CCCN(C)CC2)cc1Cl CHEMBL3961422 IC50 210.0 nM
CCCc1nn(C)c(C)c1NS(=O)(=O)c1ccc(CCCC2CCN(C)CC2)cc1 CHEMBL3935150 IC50 220.0 nM
Cc1c(NS(=O)(=O)c2ccc(CCCC3CCN(C)CC3)cc2)c(Cc2ccccc2)nn1C CHEMBL4110512 IC50 233.0 nM
Cc1c(N(C)S(=O)(=O)c2ccc(CCCC3CCN(C)CC3)cc2)c(CC(C)C)nn1C CHEMBL3939608 IC50 234.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2ccnc(N3CCNC(C(C)C)C3)c2)cc1 CHEMBL4114327 IC50 240.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CNC(C)C)c3)cc2)c(CC(C)C)nn1C CHEMBL4111223 IC50 240.0 nM
Cc1nn(C)c(C)c1N(CC(F)(F)F)S(=O)(=O)c1c(Cl)cc(CCCC2CCN(C)CC2)cc1Cl CHEMBL3358116 IC50 250.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CN4CCN(C)CC4)c3)cc2)c(CC(C)C)nn1C CHEMBL4113273 IC50 250.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(C#CCCC2CCN(C)CC2)cc1 CHEMBL4112974 IC50 250.0 nM
COc1cccc(Cc2noc(-c3ccc(Br)cc3OC3CCNCC3)n2)c1 CHEMBL3770815 Ki 260.0 nM
COc1cccc(Cc2noc(-c3cccnc3OC3CCNCC3)n2)c1 CHEMBL3753421 Ki(app) 270.0 nM
CCN1CCC(Oc2ncccc2-c2nc(Cc3c(C)nn(C)c3C)no2)CC1 CHEMBL3754763 Ki(app) 270.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2cccc(CN)c2)cc1 CHEMBL4110553 IC50 272.0 nM
Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCOC[C@@H]2CCCCN2C)cc1Cl CHEMBL3358124 IC50 280.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1c(F)cc(-c2ccnc(N3CCNCC3)c2)cc1F CHEMBL4115085 IC50 290.0 nM
CCN(c1c(C)nn(C)c1C)S(=O)(=O)c1c(Cl)cc(CCCCCCn2ccnc2)cc1Cl CHEMBL3358110 IC50 300.0 nM
CCc1nc(C)c(COc2c(Cl)cc(-c3ccnc(N4CCNCC4)c3)cc2Cl)s1 CHEMBL4076087 IC50 300.0 nM
Cc1ncccc1COc1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl CHEMBL4083888 IC50 300.0 nM
Cc1ncccc1COc1ccc(-c2cccc(C3CCNCC3)c2)cc1 CHEMBL4101887 IC50 300.0 nM
Cc1nccn1CCCCc1ccc([C@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC2CCCCC2)cc1 CHEMBL62081 IC50 307.0 nM
CCN(CC)Cc1cccc(-c2cc(Cl)c(S(=O)(=O)N(C)c3c(C)nn(C)c3C)c(Cl)c2)c1 CHEMBL3959914 IC50 310.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3ccc(CN(C)C)cc3)cc2)c(CC(C)C)nn1C CHEMBL4110369 IC50 314.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CNCc4cccnc4)c3)cc2)c(CC(C)C)nn1C CHEMBL4110304 IC50 330.0 nM
CCCCc1nn(C)c(C)c1NS(=O)(=O)c1ccc(CCCC2CCN(C)CC2)cc1 CHEMBL3933420 IC50 330.0 nM
COC(=O)c1ccc(N2CCCCCC2)c(NS(=O)(=O)c2ccc(CCCCC3CCN(C)CC3)cc2)c1 CHEMBL4251359 IC50 340.0 nM
CCN(c1c(C)nn(C)c1C)S(=O)(=O)c1c(Cl)cc(CCCN2CCN(C)CC2)cc1Cl CHEMBL3358108 IC50 352.0 nM
COc1cccc(Cc2noc(-c3ccc(Cl)cc3OC3CCNCC3)n2)c1 CHEMBL3753053 Ki(app) 360.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1ccc(CCCCCCCn2ccnc2)cc1 CHEMBL3899218 IC50 370.0 nM
CCOC(=O)c1cnc2ccc(OCc3ccc(N4CCNCC4)nc3)cc2c1SCCC#N CHEMBL4172252 Ki(app) 370.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(CCCN2CCN(C)CC2)cc1Cl CHEMBL3357691 IC50 390.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1ccc(CCCC2CCN(C)CC2)cc1 CHEMBL3358112 IC50 390.0 nM
CCCCc1nn(C)c(C)c1NS(=O)(=O)c1ccc(CCCCC2CCN(C)CC2)cc1 CHEMBL3896484 IC50 400.0 nM
COc1cccc(Cc2noc(-c3ccc(OC)cc3OC3CCNCC3)n2)c1 CHEMBL3753483 Ki(app) 430.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1c(Cl)cc(CCCCCn2ccnc2)cc1Cl CHEMBL3358109 IC50 470.0 nM
CCc1nccn1CCCCCCc1cc(Cl)c(S(=O)(=O)N(c2c(C)nn(C)c2C)C(F)F)c(Cl)c1 CHEMBL3971847 IC50 490.0 nM
Clc1cc(-c2ccnc(N3CCNCC3)c2)cc(Cl)c1OCCc1cccnc1 CHEMBL4089716 IC50 500.0 nM
Cc1nn(C)c(C)c1Cc1noc(-c2cccnc2OC2CCN(C)CC2)n1 CHEMBL3754678 Ki(app) 510.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CN4[C@@H](C)CC[C@@H]4C)c3)cc2)c(CC(C)C)nn1C CHEMBL4113297 IC50 520.0 nM
COc1cccc(Cc2noc(-c3ccc(F)cc3OC3CCNCC3)n2)c1 CHEMBL3754641 Ki(app) 540.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1cc(F)c(CCCN2CCN(C)CC2)cc1F CHEMBL4113229 IC50 548.0 nM
CN1CCC(N(C)c2nc(N(C)CCC#N)c3sc(C(C)(C)C)cc3n2)CC1 CHEMBL4644304 IC50 550.0 nM
Cc1cc(CN(C)C)cc(-c2ccc(S(=O)(=O)Nc3c(CC(C)C)nn(C)c3C)cc2)c1 CHEMBL4107095 IC50 560.0 nM
CC(C)C[C@H](NC(=O)CN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(N)=O CHEMBL304710 Km 600.0 nM
CC(C)c1nn(C)c(C(C)C)c1NS(=O)(=O)c1ccc(CCCC2CCN(C)CC2)cc1 CHEMBL3901961 IC50 620.0 nM
Cc1c(NS(=O)(=O)c2ccc(CCCC3CCN(C)CC3)cc2)c(CCc2ccccc2)nn1C CHEMBL3945163 IC50 630.0 nM
Cc1noc(C)c1NS(=O)(=O)c1ccc(-c2ccnc(N3CCNCC3)c2)cc1 CHEMBL4112824 IC50 650.0 nM
Clc1cc(-c2ccnc(N3CCNCC3)c2)cc(Cl)c1OCCc1ccncc1 CHEMBL4068594 IC50 700.0 nM
Clc1ccc(OC2CCNCC2)c(-c2nc(Cc3ccccc3)no2)c1 CHEMBL3754615 Ki(app) 730.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(CCCN2CCN(C)CC2)cc1Cl CHEMBL4108534 IC50 740.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3ccc(OC(F)(F)F)c(CN(C)C)c3)cc2)c(CC(C)C)nn1C CHEMBL4109936 IC50 740.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(-c2ccc(N3CCNCC3)nc2)cc1Cl CHEMBL1951293 IC50 750.0 nM
COc1cccc(Cc2noc(-c3cc(C)ccc3OC3CCNCC3)n2)c1 CHEMBL3770262 Ki 760.0 nM
COc1cccc(Cc2noc(-c3cc(OC)ccc3OC3CCNCC3)n2)c1 CHEMBL3771033 Ki 760.0 nM
Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1ccc(CCCCCN(C)C)cc1 CHEMBL3926050 IC50 760.0 nM
Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CNCCc4ccccn4)c3)cc2)c(CC(C)C)nn1C CHEMBL4112628 IC50 769.0 nM
Cc1ccnc(C)c1NS(=O)(=O)c1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl CHEMBL4108890 IC50 770.0 nM
CCN(CC)Cc1cccc(-c2cc(Cl)c(S(=O)(=O)Nc3c(CC(C)C)nn(C)c3C)c(Cl)c2)c1 CHEMBL4109393 IC50 810.0 nM
Cc1cc(CCCN2CCN(C)CC2)cc(C)c1S(=O)(=O)N(C)c1c(C)nn(C)c1C CHEMBL3984237 IC50 850.0 nM
Cc1ncsc1COc1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl CHEMBL4077369 IC50 900.0 nM
Clc1cc(-c2ccnc(N3CCNCC3)c2)cc(Cl)c1OCc1cncs1 CHEMBL4078895 IC50 900.0 nM
Cc1c(NS(=O)(=O)c2ccc(CCCN3CCN(C)CC3)cc2)c(CC(C)C)nn1C CHEMBL4108497 IC50 939.0 nM
O=C(Cc1ccc(F)cc1)Nc1ccc2[nH]cc(C3CCNCC3)c2c1 CHEMBL3344386 Ki 970.0 nM
Cc1cc(CCCN2CCN(C)CC2)cc(C)c1S(=O)(=O)Nc1c(C)nn(C)c1C CHEMBL4110886 IC50 980.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(NCCC2CCN(C)CC2)nc1 CHEMBL1951282 IC50 1000.0 nM
Fc1ccc(OC2CCNCC2)c(-c2nc(Cc3ccccc3)no2)c1 CHEMBL3753269 Ki(app) 1000.0 nM
Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(CCCN2CCNCC2)cc1 CHEMBL4112687 IC50 1000.0 nM
Cc1ncccc1COc1c(Cl)cc(CCCCC2CCN(C)CC2)cc1Cl CHEMBL4062043 IC50 1000.0 nM