Cc1cc(N)nc(C[C@H]2CNC[C@H]2NCCNCc2ccc(Cl)cc2)c1 CHEMBL474637 Ki 0.085 nM
NC(=O)[C@@H]1C[C@@H](NC(=O)[C@@H](N)CCC/N=C(\N)N[N+](=O)[O-])CN1 CHEMBL228077 Ki 0.1 nM
N=C(NCCC[C@H](N)CNCCN)N[N+](=O)[O-] CHEMBL227937 Ki 0.15 nM
Cc1cc(N)nc(C[C@H]2CNC[C@@H]2NCCNCc2cccc(Cl)c2)c1 CHEMBL526688 Ki 0.25 nM
N=C(NCCC[C@H](N)C(=O)N[C@@H](CCN)C(N)=O)N[N+](=O)[O-] CHEMBL44833 Ki 0.3 nM
NCCN[C@@H]1CNC[C@@H]1Cc1cccc(N)n1 CHEMBL510760 Ki 0.388 nM
CCSC(=N)NCCC[C@H](N)C(=O)O CHEMBL106871 Kd 1.0 nM
Cc1cc(N)nc(C[C@@H]2CNC[C@@H]2NCCNCCc2cccc(F)c2)c1 CHEMBL594682 Ki 5.3 nM
N=C(Nc1cccc(CN)c1)c1ccco1 CHEMBL96680 Ki 6.0 nM
N=C(Nc1cccc(CN)c1)c1ccco1 CHEMBL552825 Ki 6.3 nM
N=C(Nc1cccc(CN)c1)c1cccs1 CHEMBL555715 Ki 8.7 nM
N=C(Nc1cccc(CN)c1)c1cccs1 CHEMBL262040 Ki 8.7 nM
Nc1cccc(C[C@H]2CNC[C@H]2NCCCO)n1 CHEMBL475797 Ki 9.4 nM
CCCc1cc(C)cc(N)n1 CHEMBL302657 IC50 10.0 nM
CSCC(=N)Nc1cccc(CN)c1 CHEMBL555794 Ki 11.0 nM
N=C(CF)Nc1cccc(CN)c1 CHEMBL555584 Ki 11.0 nM
N=C(CF)Nc1cccc(CN)c1 CHEMBL455310 Ki 11.0 nM
CSCC(=N)Nc1cccc(CN)c1 CHEMBL476988 Ki 11.0 nM
O=c1cc(CN(c2cccc(Cl)c2)c2cnccn2)c2ccc(F)c(F)c2[nH]1 CHEMBL1944717 IC50 12.0 nM
CNCCCc1cncc(CCc2cc(C)cc(N)n2)c1 CHEMBL3818373 Ki 13.0 nM
CN(C)CCCN1CCSc2cc(/N=C(\N)c3cccs3)ccc21 CHEMBL3675250 IC50 14.0 nM
N=C(NCCC[C@H](N)C(=O)O)N[N+](=O)[O-] CHEMBL227744 Ki 15.0 nM
CC1CCN=C(N)C1 CHEMBL6808 IC50 16.0 nM
N=C(N)SCCc1ccc(CCSC(=N)N)cc1 CHEMBL444422 Ki 16.0 nM
Cc1cc(N)nc(C[C@H]2CNC[C@@H]2NCCNCCc2cccc(F)c2)c1 CHEMBL1233715 Ki 17.7 nM
Cc1cc(N)nc(CCc2cc(CCN(C)C)cc(F)c2F)c1 CHEMBL5420690 Ki 19.0 nM
CN1CCC[C@H]1CCn1ccc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3216307 IC50 20.0 nM
Cc1cc(CCNCc2ccc3ccc(N)nc3c2)ccc1C#N CHEMBL4068062 Ki 20.0 nM
C[C@@H]1CC(N)=N[C@@H]2CCC[C@H]12 CHEMBL191242 IC50 21.0 nM
N#Cc1ccc(CCNCc2ccc3ccc(N)nc3c2)cc1Cl CHEMBL4089246 Ki 21.0 nM
Cc1cc(N)nc(CCc2cc(CC[C@H]3CCCN3C)cc(F)c2F)c1 CHEMBL4532683 Ki 21.0 nM
CNCCCc1cc(C)cc(N)n1 CHEMBL5191295 Ki 21.0 nM
Cc1cc(N)nc(CCc2cc(CC[C@H]3CCN3C)cc(F)c2F)c1 CHEMBL4590333 Ki 23.0 nM
Cc1cc(N)nc(C[C@H]2CNC[C@H]2NCCNCCc2ccccc2)c1 CHEMBL1187747 Ki 24.0 nM
CNCCCN1CCSc2cc(/N=C(\N)c3cccs3)ccc21 CHEMBL3639741 IC50 28.0 nM
CCSC(=N)N CHEMBL321691 Ki 29.0 nM
Cc1cc(N)nc(CCc2cc(CCCN(C)C)cc(F)c2F)c1 CHEMBL4440481 Ki 29.0 nM
Cc1cc(N)nc(CCCN(C)C)c1 CHEMBL5189279 Ki 29.0 nM
CCCSC(=N)N CHEMBL483092 Ki 29.0 nM
CN1CCCC1CCNc1nc2cc(NC(=N)c3cccs3)ccc2s1 CHEMBL397446 IC50 30.0 nM
Cc1cc(N)nc(CCc2cc(F)cc(CCCN(C)C)c2)c1 CHEMBL4094689 Ki 30.0 nM
Cc1cc(CCNCc2ccc3c(C)cc(N)nc3c2)ccc1C#N CHEMBL4092027 Ki 30.0 nM
CNCc1cc(C#N)cc(OCc2ccc3c(C)cc(N)nc3c2)c1 CHEMBL4079543 Ki 31.0 nM
Cc1cc(N)nc2cc(-c3ccc(OCc4cscn4)c(CN)c3)ccc12 CHEMBL4465991 Ki 31.0 nM
N#Cc1ccc(CCNCc2ccc3ccc(N)nc3c2)cc1 CHEMBL4062164 Ki 32.0 nM
CNCc1cccc(OCc2ccc3c(C)cc(N)nc3c2)c1 CHEMBL4086610 Ki 33.0 nM
N/C(=N\c1ccc2c(c1)SCCN2CCNCCO)c1cccs1 CHEMBL3675244 IC50 34.0 nM
N=C(Nc1ccc(CCNCc2cccc(Cl)c2)cc1)c1cccs1 CHEMBL293212 IC50 35.0 nM
N=C(Nc1ccc(CCNCCc2cccc(Cl)c2)cc1)c1cccs1 CHEMBL2333953 IC50 35.0 nM
C[C@H]1CC(N)=N[C@H]2CCC[C@H]21 CHEMBL433589 IC50 36.0 nM
CNCc1cc(C#N)cc(OCc2ccc3ccc(N)nc3c2)c1 CHEMBL4096049 Ki 36.0 nM
Cc1cc(N)nc(CCc2c(F)ccc(CCCN(C)C)c2F)c1 CHEMBL4578540 Ki 36.0 nM
CC(C)SC(=N)N CHEMBL483091 Ki 37.0 nM
Cc1cc(N)nc(CCc2cncc(CCCN(C)C)c2)c1 CHEMBL3818566 Ki 37.0 nM
Cc1cc(N)nc(CCc2cc(CC[C@@H]3CCCN3C)cc(F)c2F)c1 CHEMBL4450896 Ki 37.0 nM
N=C(N)SCCc1cccc(CCSC(=N)N)c1 CHEMBL107201 Ki 37.0 nM
CC(=N)Nc1ccc(CN)cc1 CHEMBL542432 Ki 40.0 nM
Cc1ccnc(N)c1 CHEMBL40833 IC50 40.0 nM
CC(=N)Nc1cccc(CN)c1 CHEMBL419740 Ki 40.0 nM
CN(C)CCN1CCc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3216124 IC50 40.0 nM
CC(=N)Nc1ccc(CNCc2cccc(C(C)=N)c2)cc1 CHEMBL540048 Ki 42.0 nM
NC1=Nc2cc(CCCNCc3cccc(Cl)c3)ccc2[C@H]2CCC[C@@H]12 CHEMBL162416 IC50 42.0 nM
NC1=Nc2cc(CCCNCc3cccc(Cl)c3)ccc2[C@H]2CCC[C@@H]12 CHEMBL545441 IC50 42.0 nM
CC(=N)Nc1cccc(CNCc2cccc(C(C)=N)c2)c1 CHEMBL482699 Ki 42.0 nM
Cc1cc(N)nc(CCc2cccc(CCCN(C)C)c2)c1 CHEMBL4074188 Ki 43.0 nM
CNCC#Cc1cc(F)c(F)c(CCc2cc(C)cc(N)n2)c1 CHEMBL4454695 Ki 43.0 nM
Cc1cc(N)nc2cc(-c3ccc(OCc4cccnc4)c(CN)c3)ccc12 CHEMBL4576585 Ki 45.0 nM
Cc1ccccc1CN(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cnccn1 CHEMBL1944884 IC50 46.0 nM
CN[C@@H](C)Cc1cc(C#N)cc(OCc2ccc3c(C)cc(N)nc3c2)c1 CHEMBL4105240 Ki 46.0 nM
Cc1cc(N)nc2cc(-c3ccc(OCC4CC4)c(CN)c3)ccc12 CHEMBL4449970 Ki 46.0 nM
Cc1cc(N)nc2cc(-c3ccc(OCc4cncs4)c(CN)c3)ccc12 CHEMBL4534970 Ki 46.0 nM
Cc1cc(N)nc(CCc2cc(CCCN(C)C)c(F)c(F)c2F)c1 CHEMBL4548400 Ki 46.0 nM
NC1=Nc2cc(CCNCc3cccc(Cl)c3)ccc2[C@H]2CCC[C@@H]12 CHEMBL542132 IC50 48.0 nM
Cc1cc(N)nc(CCCN2CCC(F)(F)CC2)c1 CHEMBL5182377 Ki 48.0 nM
Cc1cc(N)nc(/C=C/c2cc(CCN(C)C)cc(F)c2F)c1 CHEMBL5440570 Ki 48.0 nM
CCC[C@@H]1COc2ccsc2C(N)=N1 CHEMBL1221703 IC50 50.0 nM
Cc1cc(N)nc(C[C@@H]2CNC[C@@H]2OCCNCCc2cccc(F)c2)c1 CHEMBL607146 Ki 50.0 nM
CCNCCN1CCSc2ccc(/N=C(\N)c3cccs3)cc21 CHEMBL3675251 IC50 50.0 nM
N#Cc1cccc(CCNCc2ccc3ccc(N)nc3c2)c1 CHEMBL4090184 Ki 50.0 nM
CN(C)CCOc1ccc(-c2cccc(N)n2)c2c1CCC2 CHEMBL43678 IC50 50.6 nM
CNCc1cccc(CCc2ccc3c(C)cc(N)nc3c2)c1 CHEMBL4074659 Ki 51.0 nM
Cc1cc(N)nc(C[C@H]2CNC[C@H]2NCCNCCc2cccc(F)c2)c1 CHEMBL480419 Ki 52.0 nM
Cc1cc(N)nc2cc(CNCCc3ccc(C#N)cc3)ccc12 CHEMBL4064297 Ki 52.0 nM
CNCc1cc(OCc2ccc3c(C)cc(N)nc3c2)ccc1Cl CHEMBL4066044 Ki 52.0 nM
Cc1cc(N)nc(CCc2cc(F)cc(CC[C@@H]3CCCN3C)c2)c1 CHEMBL4467114 Ki 52.0 nM
C[C@@H]1CC(N)=N[C@@H]2CCCC[C@H]12 CHEMBL191675 IC50 53.0 nM
CCc1cc(-c2cccc(N)n2)c(OC)cc1CN(C)C CHEMBL364188 IC50 54.0 nM
CNCc1cc(OCc2ccc3c(C)cc(N)nc3c2)cc(C#N)c1F CHEMBL4078757 Ki 54.0 nM
CCN(CC)CCc1cc(F)c(F)c(CCc2cc(C)cc(N)n2)c1 CHEMBL5418233 Ki 54.0 nM
CNCCN(C)c1cc(C#N)cc(CCc2cc(C)cc(N)n2)c1 CHEMBL3586664 Ki 55.0 nM
CNCCCc1cccc(CCc2cc(C)cc(N)n2)c1 CHEMBL4103382 Ki 55.0 nM
COc1cc(N)nc(CCc2cc(CCN(C)C)cc(F)c2F)c1 CHEMBL5428041 Ki 55.0 nM
CNCc1ccc(NC(C)=N)cc1 CHEMBL539793 Ki 56.0 nM
CNCc1cccc(NC(C)=N)c1 CHEMBL496134 Ki 56.0 nM
Cc1cc(N)nc(CCc2cccc(N(C)CCN)c2)c1 CHEMBL3586658 Ki 56.0 nM
CNCc1cc(C#N)cc(CCc2ccc3c(C)cc(N)nc3c2)c1 CHEMBL4061701 Ki 56.0 nM
CCc1cc(-c2cccc(N)n2)c(OC)cc1OCCN(C)C CHEMBL183892 IC50 58.0 nM
CCCOc1ccc(-c2ccc3c(C)cc(N)nc3c2)cc1CN CHEMBL4588416 Ki 58.0 nM
Cc1cc(N)nc(CCc2c(F)c(F)cc(CCCN(C)C)c2F)c1 CHEMBL4455796 Ki 58.0 nM
CNCC#Cc1cc(F)cc(CCc2cc(C)cc(N)n2)c1 CHEMBL4588581 Ki 58.0 nM
Cc1cc(N)nc(CCCCN(C)C)c1 CHEMBL5186489 Ki 58.0 nM
CNCCN(C)c1cncc(CCc2cc(C)cc(N)n2)c1 CHEMBL3586661 Ki 59.0 nM
Cc1cc(N)nc(CCc2cc(F)cc(CC[C@H]3CCCN3)c2)c1 CHEMBL4562481 Ki 59.0 nM
CC1CC(N)=NC(C)C1 CHEMBL269076 IC50 60.0 nM
NC1=NC(c2ccco2)Nc2c(F)ccc(F)c21 CHEMBL354788 IC50 60.0 nM
CSC(=N)NCCC[C@H](N)C(=O)O CHEMBL106516 IC50 60.0 nM
CN1CCC[C@@H]1CCn1ccc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3217186 IC50 60.0 nM
O=c1cc(CN(Cc2ccccc2Cl)c2cnccn2)c2ccc(F)c(F)c2[nH]1 CHEMBL1944721 IC50 60.0 nM
CNCCN1CCSc2cc(/N=C(\N)c3cccs3)ccc21 CHEMBL3675236 IC50 60.0 nM
Cc1cc(N)nc2cc(-c3cccc(CN)c3)ccc12 CHEMBL4483429 Ki 60.0 nM
CNCCc1cc(C#N)cc(OCc2ccc3c(C)cc(N)nc3c2)c1 CHEMBL4099944 Ki 61.0 nM
Cn1ncc2c(N(Cc3cc(=O)[nH]c4c(F)c(F)ccc34)c3cccc(Cl)c3)ncnc21 CHEMBL1945066 IC50 62.0 nM
Cc1cc(N)nc2cc(-c3ccc(OCc4cocn4)c(CN)c3)ccc12 CHEMBL4555914 Ki 63.0 nM
O=c1cc(CN(Cc2ccccc2F)c2cnccn2)c2ccc(F)c(F)c2[nH]1 CHEMBL1944724 IC50 64.0 nM
CNCCN(C)c1cccc(CCc2cc(C)cc(N)n2)n1 CHEMBL3586660 Ki 64.0 nM
CNCCCc1cc(F)cc(CCc2cc(C)cc(N)n2)c1 CHEMBL4079135 Ki 65.0 nM
CN[C@H](C)Cc1cc(C#N)cc(OCc2ccc3c(C)cc(N)nc3c2)c1 CHEMBL4084387 Ki 65.0 nM
Cc1cc(N)nc2cc(-c3ccc(OC(C)C)c(CN)c3)ccc12 CHEMBL4465509 Ki 66.0 nM
Cc1cc(N)nc(CCc2cc(F)cc(CC[C@@H]3CCCN3)c2)c1 CHEMBL4534409 Ki 68.0 nM
O=c1cc(CN(c2cccc(Cl)c2)c2ncccn2)c2ccc(F)c(F)c2[nH]1 CHEMBL1944718 IC50 69.0 nM
Cn1cncc1C(=O)N(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cccc(Cl)c1 CHEMBL491923 EC50 70.0 nM
CN1CCCC1CCn1ccc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3216099 IC50 70.0 nM
N=C(Nc1ccc2c(c1)N(CCNCCO)CC2)c1cccs1 CHEMBL1955937 IC50 70.0 nM
CN(C)CCOc1ccc(-c2cccc(N)n2)c2c1CCCC2 CHEMBL43815 IC50 70.0 nM
CN1CCC(Oc2ccc(-c3cccc(N)n3)c3ccccc23)C1 CHEMBL43240 IC50 70.3 nM
Cc1cc(N)nc2cc(-c3ccc(OCC(C)C)c(CN)c3)ccc12 CHEMBL4469820 Ki 72.0 nM
COc1ccncc1CCCNCc1ccc2ccc(N)nc2c1 CHEMBL4097898 Ki 73.0 nM
CNC(C)Cc1cc(C#N)cc(OCc2ccc3c(C)cc(N)nc3c2)c1 CHEMBL4081945 Ki 74.0 nM
CCc1cc(-c2cccc(N)n2)c(OC)cc1CCCN(C)C CHEMBL185444 IC50 75.0 nM
CCc1cc(-c2cccc(N)n2)c(OC)cc1CCN(C)C CHEMBL363318 IC50 75.0 nM
CN(C)c1cccc(CCNCc2ccc3ccc(N)nc3c2)c1 CHEMBL4082338 Ki 76.0 nM
Cc1cc(N)nc2cc(-c3ccc(OCc4ccccn4)c(CN)c3)ccc12 CHEMBL4535045 Ki 76.0 nM
CCc1cc(CNC)cc(OCc2ccc3c(C)cc(N)nc3c2)c1 CHEMBL4087425 Ki 78.0 nM
CCC1N=C(N)CC1C CHEMBL185024 IC50 80.0 nM
CN1CCC(N(C)Cc2cc(Cl)ccc2[N+](=O)[O-])CC1 CHEMBL272708 IC50 80.0 nM
C[C@H]1CN=C(N)c2sccc2O1 CHEMBL1221702 IC50 80.0 nM
CN1CCC(N2CCCCc3cc(NC(=N)c4cccs4)ccc32)C1 CHEMBL3216558 IC50 80.0 nM
N=C(Nc1ccc2c(c1)CCN2C1CCNC1)c1cccs1 CHEMBL3216566 IC50 80.0 nM
CNCCN1CCOc2ccc(/N=C(\N)c3cccs3)cc21 CHEMBL3675238 IC50 80.0 nM
CNCCN1CCSc2ccc(/N=C(\N)c3cccs3)cc21 CHEMBL3675255 IC50 80.0 nM
Cc1cc(N)nc(CCc2cc(CCN)cc(F)c2F)c1 CHEMBL5436523 Ki 81.0 nM
CNCc1cccc(-c2cncc(CCc3cc(C)cc(N)n3)c2)c1 CHEMBL4071288 Ki 82.0 nM
CNCc1cccc(-c2cc(F)cc(CCc3cc(C)cc(N)n3)c2)c1 CHEMBL4062639 Ki 83.0 nM
Cc1cc(N)nc(CCc2cncc(N3CCN(C)CC3)c2)c1 CHEMBL3818545 Ki 84.0 nM
Cc1cc(N)nc(CCc2cc(C#CCN(C)C)cc(F)c2F)c1 CHEMBL4573329 Ki 84.0 nM
Cc1cc(N)nc(CCc2cc(F)cc(CC[C@H]3CCCN3C)c2)c1 CHEMBL4521220 Ki 84.0 nM
N=C(Nc1ccc2c(c1)CCCN2CCCN1CCCC1)c1cccs1 CHEMBL3216315 IC50 86.0 nM
CCO[C@@H]1C[C@H](CCc2cc(F)c(F)c(CCc3cc(C)cc(N)n3)c2)N(C)C1 CHEMBL4530822 Ki 87.0 nM
Cc1cc(N)nc2cc(-c3ccc(CN)cc3)ccc12 CHEMBL4522356 Ki 88.0 nM
Cc1cc(N)nc(CCc2cncc(C3CCN(C)CC3)c2)c1 CHEMBL3819551 Ki 89.0 nM
Cc1cc(N)nc(CCc2cc(CC[C@H]3COCCN3C)cc(F)c2F)c1 CHEMBL4547754 Ki 89.0 nM
Cc1cc(N)nc(CCc2cc(CCN3CCN(C)CC3)cc(F)c2F)c1 CHEMBL5399195 Ki 89.0 nM
CNC(=N)NCCC[C@H](N)C(=O)O CHEMBL256147 IC50 90.0 nM
CN1CCCCC1CCn1ccc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3216762 IC50 90.0 nM
Cc1cc(N)nc(CCc2cncc(C(CN)Cc3cc(C)cc(N)n3)c2)c1 CHEMBL3262024 Ki 90.0 nM
C=CCC(=N)NCCC[C@H](N)C(=O)O CHEMBL106820 Ki 90.0 nM
CC[C@H]1N=C(N)[Se][C@@H]1C CHEMBL182193 IC50 92.0 nM
CNCC#Cc1cc(C)cc(N)n1 CHEMBL5176637 Ki 92.0 nM
CN(C)CCN1CCCc2cc(NC(=N)c3cccs3)cc(F)c21 CHEMBL3216545 IC50 93.0 nM
Cc1cc(N)nc2cc(-c3ccc(OCC4CCC4)c(CN)c3)ccc12 CHEMBL4521790 Ki 96.0 nM
Nc1cccc(-c2ccc(OCC3CC4CCN3CC4)c3ccccc23)n1 CHEMBL39186 IC50 96.3 nM
Cc1noc(C)c1C(=O)N(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cccc(Cl)c1 CHEMBL492090 EC50 97.0 nM
CCN(C)CCN1CCCc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3216119 IC50 97.0 nM
Cc1cc(C)nc(N)c1 CHEMBL59925 IC50 98.0 nM
CN1CCC[C@H]1CCN1CCCc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3142403 IC50 98.0 nM
CNCCN(C)c1cccc(CCc2cc(C)cc(N)n2)c1 CHEMBL3586656 Ki 98.0 nM
Cc1cc(N)nc(C[C@H]2CNC[C@H]2NCCN)c1 CHEMBL1186876 Ki 98.0 nM
Cc1cc(N)nc(CC(C)C)c1 CHEMBL294609 IC50 100.0 nM
NC1=Nc2ccccc2[C@H]2CCC[C@@]12F CHEMBL349071 IC50 100.0 nM
COc1cccc(CN2CCC(Nc3nc4ccc(NC(=N)c5cccs5)cc4s3)CC2)c1 CHEMBL233655 IC50 100.0 nM
N=C(N)SCc1ccc(CSC(=N)N)cc1 CHEMBL501448 Ki 100.0 nM
O=c1cc(CN(Cc2ccccc2)c2cnccn2)c2ccc(F)c(F)c2[nH]1 CHEMBL1944720 IC50 100.0 nM
CNCCN1CCCCc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3216995 IC50 100.0 nM
CNC1CCC(N2CCc3cc(NC(=N)c4cccs4)ccc32)CC1 CHEMBL3142587 IC50 100.0 nM
CNCc1ccc(-c2cncc(CCc3cc(C)cc(N)n3)c2)cc1 CHEMBL4084332 Ki 100.0 nM
CNCCN(C)c1cc(F)cc(CCc2cc(C)cc(N)n2)c1 CHEMBL3586663 Ki 105.0 nM
Cc1cc(COc2ccc(-c3ccc4c(C)cc(N)nc4c3)cc2CN)no1 CHEMBL4468534 Ki 106.0 nM
Nc1ccc2ccc(CNCCCc3cccnc3)cc2n1 CHEMBL4071836 Ki 108.0 nM
CN(C)CCOc1ccc(-c2cccc(N)n2)c2c1CCCCC2 CHEMBL42969 IC50 109.0 nM
Cc1cc(N)nc(CCc2cccc(N(C)CCCN)c2)c1 CHEMBL3586659 Ki 109.0 nM
NC1=Nc2ccc(F)cc2[C@H]2CCC[C@@H]12 CHEMBL86040 IC50 110.0 nM
N=C(Nc1ccc2c(c1)N(CCN1CC[C@@H](O)C1)CC2)c1cccs1 CHEMBL1955936 IC50 110.0 nM
N=C(Nc1ccc2c(c1)CCN2C1CCNCC1)c1cccs1 CHEMBL3216328 IC50 110.0 nM
N/C(=N\c1ccc2c(c1)N(C1CCNCC1)CCS2)c1cccs1 CHEMBL3675256 IC50 110.0 nM
Cc1cc(N)nc(CCc2cccc(N(C)CCN(C)C)c2)c1 CHEMBL3586657 Ki 111.0 nM
CCOc1ccc(-c2ccc3c(C)cc(N)nc3c2)cc1CN CHEMBL4464663 Ki 111.0 nM
CN1CCCC1COc1ccc(-c2cccc(N)n2)c2ccccc12 CHEMBL42863 IC50 112.0 nM
COc1cc(-c2cccc(N)n2)c(OC)cc1OCCN(C)C CHEMBL185247 IC50 112.0 nM
Cc1cc(N)nc2cc(-c3ccc(OCc4ccc(C#N)cc4)c(CN)c3)ccc12 CHEMBL4473567 Ki 114.0 nM
N=C(Nc1ccc2c(c1)CCCN2CCNCCO)c1cccs1 CHEMBL3217010 IC50 115.0 nM
Nc1cccc(-c2ccc(OCCN3CCCC3)c3c2CCC3)n1 CHEMBL290476 IC50 117.0 nM
CN(C)CCOc1ccc(-c2cccc(N)n2)c2c1C1CCC2C1 CHEMBL39005 IC50 120.0 nM
CCSC(=N)Nc1ccccc1 CHEMBL545673 Ki 120.0 nM
CCSC(=N)Nc1ccccc1 CHEMBL451666 Ki 120.0 nM
Cc1ncsc1C(=O)N(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cccc(Cl)c1 CHEMBL489724 EC50 120.0 nM
CN1CCCC(n2ccc3cc(NC(=N)c4cccs4)ccc32)CC1 CHEMBL3217174 IC50 120.0 nM
CN1CCC(c2c[nH]c3cc(NC(=N)c4cccs4)ccc23)CC1 CHEMBL3215870 IC50 120.0 nM
O=c1cc(CN(Cc2ccc(Cl)cc2)c2cnccn2)c2ccc(F)c(F)c2[nH]1 CHEMBL1944723 IC50 120.0 nM
N=C(Nc1ccc2c(c1)CCN2CCN1CCCC1)c1cccs1 CHEMBL3215893 IC50 120.0 nM
CN(C)CCN1CCSc2cc(/N=C(\N)c3cccs3)ccc21 CHEMBL3675240 IC50 120.0 nM
CN1CCN(CCOc2ccc(-c3cccc(N)n3)c3c2CCCC3)CC1 CHEMBL416071 IC50 121.0 nM
Cc1cc(N)nc2cc(-c3ccc(CCN)cc3)ccc12 CHEMBL4459441 Ki 122.0 nM
CN1CCN(CCOc2ccc(-c3cccc(N)n3)c3c2CCC3)CC1 CHEMBL290875 IC50 123.0 nM
Cc1cc(N)nc(CCc2cc(F)cc(C#CCN(C)C)c2)c1 CHEMBL4557453 Ki 124.0 nM
Clc1cccc(CCCNCCc2ccnc(-n3ccnc3)n2)c1 CHEMBL3407811 Ki 125.0 nM
c1cncc(CCCNCCc2ccnc(-n3ccnc3)n2)c1 CHEMBL3407814 Ki 125.0 nM
CCc1cc(CNC)cc(OCc2ccc3ccc(N)nc3c2)c1 CHEMBL4068739 Ki 125.0 nM
Cc1cc(N)nc(CCc2cc(F)cc(CC[C@@H]3C[C@H](F)CN3)c2)c1 CHEMBL4446153 Ki 129.0 nM
N=C(NCCC[C@H](N)C(=O)N[C@@H](CCN)C(N)=O)N[N+](=O)[O-] CHEMBL1204421 Ki 130.0 nM
NC1=Nc2cc(F)ccc2[C@H]2CCC[C@@H]12 CHEMBL315617 IC50 130.0 nM
NC1=Nc2ccccc2[C@H]2COC[C@@H]12 CHEMBL315966 IC50 130.0 nM
CC1CC(N)=NC1C CHEMBL185584 IC50 130.0 nM
CCN1CCCC1CNCCCn1ccc2cc(NC(=N)c3cccs3)ccc21 CHEMBL1825167 IC50 130.0 nM
CN1CCC[C@@H]1CCN1CCCc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3216112 IC50 130.0 nM
COc1cc(N(Cc2cc(=O)[nH]c3c(F)c(F)ccc23)c2cccc(Cl)c2)ncn1 CHEMBL1945065 IC50 130.0 nM
CN(C)CCN1CCSc2ccc(/N=C(\N)c3cccs3)cc21 CHEMBL3675254 IC50 130.0 nM
Cc1ccncc1CCCNCc1ccc2ccc(N)nc2c1 CHEMBL4092616 Ki 130.0 nM
CN(CCO)CCN1CCCc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3216120 IC50 133.0 nM
CNCc1cc(OC)cc(OCc2ccc3ccc(N)nc3c2)c1 CHEMBL4060083 Ki 136.0 nM
Nc1cccc(-c2ccc(CCN3CCN(C(=O)Cc4ccccc4)CC3)cc2)n1 CHEMBL87544 IC50 137.0 nM
Fc1cccc(C[C@@H]2C[C@H]2NCCc2ccnc(-n3ccnc3)n2)c1 CHEMBL3407822 Ki 137.0 nM
N#Cc1cccc(CNCCc2ccnc(-n3ccnc3)n2)c1 CHEMBL3407815 Ki 138.0 nM
CCNCCN1CCCc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3217217 IC50 139.0 nM
Nc1cccc(-c2ccc(CCN3CCN(CC(=O)c4ccccc4)CC3)cc2)n1 CHEMBL40391 IC50 140.0 nM
NC1=Nc2ccc(Cl)cc2[C@H]2CCC[C@@H]12 CHEMBL292099 IC50 140.0 nM
NC1=Nc2cc(CNCc3cccc(Cl)c3)ccc2[C@H]2CCC[C@@H]12 CHEMBL544514 IC50 140.0 nM
CCSC(=N)Nc1ccc(Cl)cc1 CHEMBL543806 Ki 140.0 nM
CCC1CC(N)=NC1C CHEMBL363477 IC50 140.0 nM
CCCN(Cc1cc(Cl)ccc1C#N)C1CCNCC1 CHEMBL256378 IC50 140.0 nM
CCSC(=N)Nc1ccc(Cl)cc1 CHEMBL449605 Ki 140.0 nM
CC(=O)CN1CCN(CCc2ccc(-c3cccc(N)n3)cc2)CC1 CHEMBL2333952 IC50 140.0 nM
CN(C)CCN1CCSc2cc(/N=C(\N)c3ccco3)ccc21 CHEMBL3675247 IC50 140.0 nM
N/C(=N\c1ccc2c(c1)SCCN2CCN1CCCCC1)c1cccs1 CHEMBL3675242 IC50 140.0 nM
N/C(=N\c1ccc2c(c1)SCCN2CCCN1CCCC1)c1cccs1 CHEMBL3675249 IC50 140.0 nM
Nc1cccc(-c2ccc(OCCN3CCCC3)c3c2CCCC3)n1 CHEMBL42968 IC50 141.0 nM
CNCc1ccc(-c2ccc3c(C)cc(N)nc3c2)cc1 CHEMBL4446903 Ki 149.0 nM
Cc1cc(N)nc(CCCN2CC(F)(F)C2)c1 CHEMBL5204779 Ki 149.0 nM
COC(=O)[C@@H](N)CCCNC(=N)N[N+](=O)[O-] CHEMBL7890 IC50 150.0 nM
CN(Cc1cc(Cl)ccc1C#N)C1CCN(CCc2ccccc2)CC1 CHEMBL428069 IC50 150.0 nM
CCN(CC)CCCn1ccc2ccc(NC(=N)c3cccs3)cc21 CHEMBL3216735 IC50 150.0 nM
O=c1cc(CN(c2cccc(Cl)c2)c2ccncn2)c2ccc(F)c(F)c2[nH]1 CHEMBL1944716 IC50 150.0 nM
CCN(CC)CCN1CCSc2cc(/N=C(\N)c3cccs3)ccc21 CHEMBL3675243 IC50 150.0 nM
N/C(=N\c1ccc2c(c1)N(CCNCCO)CCS2)c1cccs1 CHEMBL3675253 IC50 150.0 nM
Cc1cc(N)nc2cc(-c3ccccc3CN)ccc12 CHEMBL4438715 Ki 151.0 nM
Cc1cc(N)nc(CCc2cc(F)cc(CCCN(C)C)c2F)c1 CHEMBL4528697 Ki 157.0 nM
NC1=Nc2ccccc2[C@H]2CCC[C@@H]12 CHEMBL61969 IC50 160.0 nM
NC1=NCCCOC1 CHEMBL362772 IC50 160.0 nM
CSC(=N)N CHEMBL356703 Ki 160.0 nM
N=C(Nc1ccc2c(c1)CCC(=O)N2CCN1CCCC1)c1cccs1 CHEMBL3215655 IC50 160.0 nM
Cc1cc(N(Cc2cc(=O)[nH]c3c(F)c(F)ccc23)c2cccc(Cl)c2)ncn1 CHEMBL1944887 IC50 160.0 nM
N=C(Nc1ccc2c(c1)CCCCN2CCN1CCCC1)c1cccs1 CHEMBL3216115 IC50 160.0 nM
N=C(Nc1ccc2c(c1)CCN2C1CCN(CCO)CC1)c1cccs1 CHEMBL3215678 IC50 160.0 nM
CNCCN1CCSc2cc(/N=C(\N)c3ccco3)ccc21 CHEMBL3675248 IC50 160.0 nM
CN(C)C1CCCCC1Oc1ccc(-c2cccc(N)n2)c2ccccc12 CHEMBL41343 IC50 161.0 nM
Nc1ccc2ccc(CNCCCc3cncc(F)c3)cc2n1 CHEMBL4070784 Ki 164.0 nM
N=C(Nc1ccc2c(c1)CCCN2CCCNCCO)c1cccs1 CHEMBL3216787 IC50 169.0 nM
CCC1N=C(N)CC1C CHEMBL552935 IC50 170.0 nM
CC(=N)Nc1ccc(CN(C)C)cc1 CHEMBL554201 Ki 170.0 nM
NC1=Nc2c(F)cccc2[C@H]2CCC[C@@H]12 CHEMBL314943 IC50 170.0 nM
NC1=Nc2cc(CCNCc3cccc(Cl)c3)c(Cl)cc2[C@H]2CCC[C@@H]12 CHEMBL552822 IC50 170.0 nM
CNCCOc1ccc2c(c1)N=C(N)[C@@H]1CCC[C@H]21 CHEMBL538997 IC50 170.0 nM
CCSC(=N)Nc1ccccc1OC CHEMBL543085 Ki 170.0 nM
CCSC(=N)Nc1ccccc1Cl CHEMBL541296 Ki 170.0 nM
CC(=N)Nc1cccc(CN(C)C)c1 CHEMBL502800 Ki 170.0 nM
CCSC(=N)Nc1ccccc1OC CHEMBL502814 Ki 170.0 nM
CCSC(=N)Nc1ccccc1Cl CHEMBL448974 Ki 170.0 nM
O=[N+]([O-])c1cccc2c(Br)n[nH]c12 CHEMBL479014 IC50 170.0 nM
CN(C)CCn1ccc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3216306 IC50 170.0 nM
N=C(Nc1ccc2c(ccn2CCN2CCCCC2)c1)c1cccs1 CHEMBL3215643 IC50 170.0 nM
O=c1cc(CN(c2cccc(Cl)c2)c2ccccn2)c2ccc(F)c(F)c2[nH]1 CHEMBL1944712 IC50 170.0 nM
Cc1cc(N)nc(CCCN2CCN(C)CC2)c1 CHEMBL5204256 Ki 171.0 nM
CNCCN1CCCc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3216121 IC50 176.0 nM
CCSC(=N)Nc1ccc(C)cc1 CHEMBL543098 Ki 180.0 nM
CCSC(=N)Nc1ccc(C)cc1 CHEMBL476196 Ki 180.0 nM
N=C(Nc1ccc2c(c1)N(C1CCNC1)CC2)c1cccs1 CHEMBL1955938 IC50 180.0 nM
CNCCN(C)c1cc(CCc2cc(C)cc(N)n2)cc(C(F)(F)F)c1 CHEMBL3586662 Ki 189.0 nM
N=C(CN)Nc1cccc(CN)c1 CHEMBL542675 Ki 190.0 nM
Cc1ccc2c(c1)N=C(N)[C@@H]1CCC[C@H]21 CHEMBL315967 IC50 190.0 nM
CCSC(=N)Nc1ccc(Oc2ccccc2)cc1 CHEMBL540783 Ki 190.0 nM
C[C@@H]1CC(N)=N[C@H]2CCCC[C@@H]12 CHEMBL365804 IC50 190.0 nM
CN(Cc1cc(Cl)ccc1C#N)C1CCCNC1 CHEMBL271248 IC50 190.0 nM
CC(C)N(Cc1cc(Cl)ccc1C#N)C1CCNCC1 CHEMBL428248 IC50 190.0 nM
N=C(CN)Nc1cccc(CN)c1 CHEMBL482908 Ki 190.0 nM
CCSC(=N)Nc1ccc(Oc2ccccc2)cc1 CHEMBL524703 Ki 190.0 nM
CN1CC=C(c2c[nH]c3ccc(NC(=N)c4cccs4)cc23)CC1 CHEMBL3217207 IC50 190.0 nM
CN1CCCC1CCN1CCSc2cc(/N=C(\N)c3cccs3)ccc21 CHEMBL3675241 IC50 190.0 nM
Fc1cccc(CCCNCCc2ccnc(-n3ccnc3)n2)c1 CHEMBL3407810 Ki 193.0 nM
COc1cc(-c2cccc(N)n2)c(OC)cc1CCCN(C)C CHEMBL184794 IC50 200.0 nM
N=C(Nc1ccc2sc(N)nc2c1)c1cccs1 CHEMBL233228 IC50 200.0 nM
COc1ccc(CN2CCC(Nc3nc4ccc(NC(=N)c5cccs5)cc4s3)CC2)cc1 CHEMBL234498 IC50 200.0 nM
N=C(Nc1ccc2nc(NC3CCN(Cc4ccc(F)cc4)CC3)sc2c1)c1cccs1 CHEMBL233444 IC50 200.0 nM
N=C(Nc1ccc2nc(NCCN3CCOCC3)sc2c1)c1cccs1 CHEMBL412797 IC50 200.0 nM
N=C(Nc1ccc2nc(N)sc2c1)c1cccs1 CHEMBL397506 IC50 200.0 nM
CN1CCC[C@H]1CCn1ccc2ccc(NC(=N)c3cccs3)cc21 CHEMBL3216280 IC50 200.0 nM
CN1CCC(c2c[nH]c3cc(NC(=N)c4cccs4)ccc23)C1 CHEMBL3216105 IC50 200.0 nM
CCN[C@H]1CCC[C@H](c2c[nH]c3ccc(NC(=N)c4cccs4)cc23)C1 CHEMBL2036276 IC50 200.0 nM
CN1CCC(N2CCc3cc(NC(=N)c4cccs4)ccc32)CC1 CHEMBL3216789 IC50 200.0 nM
CN(C)CCN1CCOc2cc(/N=C(\N)c3cccs3)ccc21 CHEMBL3675234 IC50 200.0 nM
N/C(=N\c1ccc2c(c1)N(CCN1CCCC1)CCS2)c1cccs1 CHEMBL3675252 IC50 200.0 nM
CN(C)CCN1CCOc2ccc(/N=C(\N)c3cccs3)cc21 CHEMBL3675237 IC50 200.0 nM
CN1CCC[C@H]1CCn1ccc2ccc(/N=C(\N)c3cccs3)cc21 CHEMBL1852332 IC50 200.0 nM
CN(C)C1CCN(CCOc2ccc(-c3cccc(N)n3)c3ccccc23)CC1 CHEMBL38762 IC50 203.0 nM
Cc1cc(N)nc(CCc2cc(F)cc(CC[C@@H]3C[C@H](F)CN3C)c2)c1 CHEMBL4474392 Ki 204.0 nM
CCSC(=N)Nc1ccc(OCc2ccccc2)cc1 CHEMBL540280 Ki 210.0 nM
CCSC(=N)Nc1ccc(OCc2ccccc2)cc1 CHEMBL500923 Ki 210.0 nM
Cc1cc(N)nc(C[C@H]2CNC[C@H]2NCCNCc2cccc(C(F)(F)F)c2)c1 CHEMBL1186802 Ki 210.0 nM
Nc1cccc(-c2ccc(CCN3CCN(c4cccc5cccnc45)CC3)cc2)n1 CHEMBL87187 IC50 212.0 nM
Cc1nccc(N(Cc2cc(=O)[nH]c3c(F)c(F)ccc23)c2cccc(Cl)c2)n1 CHEMBL1944886 IC50 213.0 nM
CN(C)CCOc1ccc(-c2cccc(N)n2)c2ccccc12 CHEMBL43245 IC50 220.0 nM
CN1CCCC1CCn1ccc2ccc(NC(=N)c3cccs3)cc21 CHEMBL3216522 IC50 220.0 nM
CN1CCCC1CCn1ccc2ccc(/N=C(\N)c3cccs3)cc21 CHEMBL1852338 IC50 220.0 nM
CC(=N)NCCC[C@H](N)C(=O)O CHEMBL11471 Ki 230.0 nM
COc1cc(-c2cccc(N)n2)c(OC)cc1CCN(C)C CHEMBL184355 IC50 235.0 nM
CNCCCN1CCCc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3215891 IC50 235.0 nM
CCCC1CCCCC/C(N)=N\1 CHEMBL113438 IC50 240.0 nM
COc1ccc2c(c1)N=C(N)[C@@H]1CCC[C@H]21 CHEMBL85823 IC50 240.0 nM
N=C1CCCCN1 CHEMBL269058 IC50 240.0 nM
CC1CC(N)=Nc2ccccc21 CHEMBL192033 IC50 240.0 nM
O=c1cc(CN(c2ccncc2)c2cccc(Cl)c2)c2ccc(F)c(F)c2[nH]1 CHEMBL1944714 IC50 240.0 nM
N/C(=N\c1ccc2c(c1)SCCN2CCN1CCCC1)c1cccs1 CHEMBL3675239 IC50 240.0 nM
NC1=N[C@H]2CCCC[C@H]2CC1 CHEMBL364230 IC50 246.0 nM
N=C(Nc1ccc2c(c1)CCCN2C1CCNC1)c1cccs1 CHEMBL3216122 IC50 248.0 nM
CN(C)CCc1cc(F)c(F)c(CCc2cc(C(F)F)cc(N)n2)c1 CHEMBL5406729 Ki 249.0 nM
Nc1cccc(-c2ccc(OCCN3CCCC3)c3ccccc23)n1 CHEMBL38845 IC50 250.0 nM
NC1=Nc2ccc([N+](=O)[O-])cc2[C@H]2CCC[C@@H]12 CHEMBL87969 IC50 250.0 nM
CCSC(=N)Nc1ccccc1Br CHEMBL552893 Ki 250.0 nM
CCSC(=N)Nc1ccccc1Br CHEMBL501450 Ki 250.0 nM
CN1CCCC1CCn1ccc2cc(NC(=N)c3ccco3)ccc21 CHEMBL3216292 IC50 250.0 nM
N=C(N)[C@H]1CCN1 CHEMBL1783094 IC50 260.0 nM
CN(C)CCCCn1ccc2ccc(NC(=N)c3cccs3)cc21 CHEMBL3216739 IC50 260.0 nM
N=C(Nc1ccc2c(ccn2CCCNC2CC2)c1)c1cccs1 CHEMBL3216305 IC50 260.0 nM
CCN(CC)CCN1CCCc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3216314 IC50 260.0 nM
CN(C)CCCCn1ccc2ccc(/N=C(\N)c3cccs3)cc21 CHEMBL1852428 IC50 260.0 nM
Nc1cccc(-c2ccc(CCN3CCN(CCc4ccccc4)CC3)cc2)n1 CHEMBL87529 IC50 264.0 nM
CC(C)NCCN1CCCc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3215675 IC50 267.0 nM
CN(C)CCCN1CCCc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3215657 IC50 270.0 nM
CN(C)c1ccc(CCNCc2ccc3ccc(N)nc3c2)cc1 CHEMBL4100356 Ki 274.0 nM
CC[C@@H]1N=C(N)[Se][C@H]1C CHEMBL179441 IC50 280.0 nM
CC[C@H]1N=C(N)[Se][C@H]1C CHEMBL178622 IC50 280.0 nM
NC1=Nc2c(F)cc(Cl)cc2[C@H]2CCC[C@@H]12 CHEMBL314186 IC50 290.0 nM
NC1=Nc2ccc(Cl)cc2[C@H]2CCC[C@@]12F CHEMBL162455 IC50 290.0 nM
CCSC(=N)Nc1ccc(OC)cc1 CHEMBL545439 Ki 290.0 nM
CCSC(=N)Nc1ccc(OC)cc1 CHEMBL503073 Ki 290.0 nM
CC1=C(C(=O)N(Cc2cc(=O)[nH]c3c(F)c(F)ccc23)c2cccc(Cl)c2)CNCC1 CHEMBL491922 EC50 290.0 nM
Nc1cccc(C[C@@H]2CNC[C@@H]2OCCNCCc2cccc(F)c2)n1 CHEMBL1230380 Ki 290.0 nM
CNCc1cc(OCc2ccc3ccc(N)nc3c2)ccc1Cl CHEMBL3735289 Ki 295.0 nM
CNCc1cc(OCc2ccc3ccc(N)nc3c2)ccc1Cl CHEMBL3736597 Ki 295.0 nM
N/C(CF)=N\c1cccc(CO)c1 CHEMBL542433 Ki 300.0 nM
COC(=O)c1ccc(CN2CCC(Nc3nc4ccc(NC(=N)c5cccs5)cc4s3)CC2)cc1 CHEMBL397710 IC50 300.0 nM
N=C(Nc1ccc2nc(NC3CCN(CCc4cnc[nH]4)CC3)sc2c1)c1cccs1 CHEMBL233653 IC50 300.0 nM
N/C(CF)=N\c1cccc(CO)c1 CHEMBL468039 Ki 300.0 nM
O=c1cc(Cn2c(C3CCC3)nc3nccnc32)c2ccc(F)c(F)c2[nH]1 CHEMBL1801504 EC50 300.0 nM
CC(C)Cc1nc2nccnc2n1Cc1cc(=O)[nH]c2c(F)c(F)ccc12 CHEMBL1801506 EC50 300.0 nM
CN[C@H]1CCC[C@H](c2c[nH]c3ccc(NC(=N)c4cccs4)cc23)C1 CHEMBL2036274 IC50 300.0 nM
Cc1cncn1-c1nccc(CCNCCCc2cccc(F)c2)n1 CHEMBL3407821 Ki 303.0 nM
NC1=Nc2cc(CCCNCc3cccc(Cl)c3)ccc2[C@H]2CCC[C@@]12F CHEMBL161925 IC50 310.0 nM
NC1=Nc2ccc(Br)cc2[C@H]2CCC[C@@H]12 CHEMBL85523 IC50 310.0 nM
NC1=Nc2cc([N+](=O)[O-])ccc2[C@H]2CCC[C@@H]12 CHEMBL83397 IC50 310.0 nM
NC1=NCC2CCCC12 CHEMBL365849 IC50 310.0 nM
c1cn(-c2nsc(N(CCCNCc3ccc4c(c3)OCO4)Cc3nccs3)n2)cn1 CHEMBL1911999 EC50 310.0 nM
Nc1ccc2ccc(CCNCCc3cccc(F)c3)cc2n1 CHEMBL3217277 Ki 318.0 nM
Nc1ccc2ccc(CCNCCc3cccc(F)c3)cc2n1 CHEMBL3139679 Ki 318.0 nM
Cc1cc(N)nc(C#Cc2cc(CN(C)C)cc(F)c2F)c1 CHEMBL5416660 Ki 319.0 nM
NC(=O)C[C@H](NC(=O)[C@@H](N)CCC/N=C(\N)N[N+](=O)[O-])C(N)=O CHEMBL1202118 Ki 320.0 nM
CCSC(=N)Nc1ccc(C(F)(F)F)cc1 CHEMBL542855 Ki 320.0 nM
CCSC(=N)Nc1ccc(C(F)(F)F)cc1 CHEMBL323542 Ki 320.0 nM
O=c1cc(Cn2c(C3CCC3)nc3ccccc32)c2ccc(F)c(F)c2[nH]1 CHEMBL1801487 EC50 320.0 nM
CN1CCC[C@@H]1CCn1ccc2ccc(NC(=N)c3cccs3)cc21 CHEMBL3142303 IC50 320.0 nM
CN1CCC[C@@H]1CCn1ccc2ccc(/N=C(\N)c3cccs3)cc21 CHEMBL1852773 IC50 320.0 nM
Cc1cc(N)nc(C#CCCN(C)C)c1 CHEMBL5175065 Ki 327.0 nM
Cc1cc(N)nc(C#Cc2cc(CCN(C)C)cc(F)c2F)c1 CHEMBL5421892 Ki 328.0 nM
CC(C)NC(=O)CN1CCN(CCc2ccc(-c3cccc(N)n3)cc2)CC1 CHEMBL87186 IC50 330.0 nM
N=C(Nc1cccc(CN)c1)c1ccccn1 CHEMBL544793 Ki 330.0 nM
NCCC[C@H](NC(=O)[C@@H](N)CCC/N=C(/N)N[N+](=O)[O-])C(N)=O CHEMBL1202106 Ki 330.0 nM
CCSC(=N)Nc1ccc(C(C)C)cc1 CHEMBL553038 Ki 330.0 nM
N=C(Nc1cccc(CN)c1)c1ccccn1 CHEMBL444240 Ki 330.0 nM
CCSC(=N)Nc1ccc(C(C)C)cc1 CHEMBL499879 Ki 330.0 nM
O=c1cc(CN(Cc2cccc(Cl)c2)c2cnccn2)c2ccc(F)c(F)c2[nH]1 CHEMBL1944722 IC50 330.0 nM
N=C(Nc1ccc2c(c1)CCCCN2C1CCNC1)c1cccs1 CHEMBL3215663 IC50 330.0 nM
N=C(Nc1ccc2c(c1)CCN2C1CCCNC1)c1cccs1 CHEMBL3217218 IC50 330.0 nM
NC1=NC(CC[N+](=O)[O-])CCCC1 CHEMBL315194 IC50 339.0 nM
Cc1cnc(N)cc1C CHEMBL293022 IC50 340.0 nM
CCSC(=N)Nc1ccc(O)cc1 CHEMBL543090 Ki 340.0 nM
CCSC(=N)Nc1ccc(O)cc1 CHEMBL500924 Ki 340.0 nM
CC(C)CN1CCN(CCc2ccc(-c3cccc(N)n3)cc2)CC1 CHEMBL86810 IC50 350.0 nM
NCCCCNC(=O)[C@@H](N)CCC/N=C(\N)N[N+](=O)[O-] CHEMBL91256 Ki 350.0 nM
CC[C@@H]1[Se]C(N)=N[C@H]1C CHEMBL178373 IC50 350.0 nM
CN(Cc1cc(Cl)ccc1C#N)C1CCNCC1 CHEMBL272697 IC50 350.0 nM
CN(C)[C@H]1CC[C@@H](c2c[nH]c3ccc(NC(=N)c4cccs4)cc32)CC1 CHEMBL2036267 IC50 350.0 nM
N=C(Nc1ccc2c(c1)CCN2CCNCCO)c1cccs1 CHEMBL3215894 IC50 350.0 nM
Fc1cccc(CC2CC2NCCc2ccnc(-n3ccnc3)n2)c1 CHEMBL3407813 Ki 358.0 nM
Fc1cccc(C2CC2CNCCc2ccnc(-n3ccnc3)n2)c1 CHEMBL3407812 Ki 359.0 nM
CC(=N)Nc1ccc(CSC(=N)N)cc1 CHEMBL544317 Ki 360.0 nM
CCN(Cc1cc(Cl)ccc1C#N)C1CCNCC1 CHEMBL403952 IC50 360.0 nM
CC(=N)Nc1cccc(CSC(=N)N)c1 CHEMBL482700 Ki 360.0 nM
O=C(c1c[nH]cn1)N(Cc1cc(=O)[nH]c2c(F)cccc12)c1cccc(Cl)c1 CHEMBL491897 EC50 360.0 nM
N=C(Nc1ccc2c(ccn2CCCNC23CC4CC(CC(C4)C2)C3)c1)c1cccs1 CHEMBL3215642 IC50 360.0 nM
N=C(Nc1ccc2c(ccn2C2CN3CCC2CC3)c1)c1cccs1 CHEMBL3215865 IC50 360.0 nM
CN1CCC(N2CCCc3cc(NC(=N)c4cccs4)ccc32)C1 CHEMBL3216110 IC50 360.0 nM
O=c1cc(CN(c2cccc(Cl)c2)c2cccnn2)c2ccc(F)c(F)c2[nH]1 CHEMBL1944715 IC50 360.0 nM
CNCc1ccc(-c2cc(F)cc(CCc3cc(C)cc(N)n3)c2)cc1 CHEMBL4061573 Ki 362.0 nM
NC(N)=Nc1ccccc1CC(N)C(=O)O CHEMBL298404 Ki 370.0 nM
CC(=N)NCc1ccc(NC(C)=N)cc1 CHEMBL545025 Ki 370.0 nM
CCN1CCC(N(C)Cc2cc(Cl)ccc2C#N)CC1 CHEMBL258310 IC50 370.0 nM
CC(=N)NCc1cccc(NC(C)=N)c1 CHEMBL466888 Ki 370.0 nM
O=c1cc(CN(c2cccnc2)c2cccc(Cl)c2)c2ccc(F)c(F)c2[nH]1 CHEMBL1944713 IC50 370.0 nM
CN[C@H]1CC[C@@H](N2CCc3ccc(NC(=N)c4cccs4)cc32)CC1 CHEMBL1956107 IC50 370.0 nM
CC1CC(N2CCc3cc(NC(=N)c4cccs4)ccc32)CCN1 CHEMBL3142586 IC50 370.0 nM
CC[C@H]1SC(N)=N[C@@H]1C CHEMBL2096770 IC50 380.0 nM
Cc1[nH]c(=N)sc1C CHEMBL450172 Ki 380.0 nM
CCCC1N=C(N)CC1C CHEMBL541081 IC50 390.0 nM
CNCCc1ccc2c(c1)N=C(N)[C@]1(F)CCC[C@H]21 CHEMBL162365 IC50 390.0 nM
CN1CCN(CCOc2ccc(-c3cccc(N)n3)c3ccccc23)CC1 CHEMBL41551 IC50 390.0 nM
CC1CCCC(N)=N1 CHEMBL265672 IC50 400.0 nM
N=C(Nc1ccc2sc(NC3CCN(Cc4ccccc4)CC3)nc2c1)c1cccs1 CHEMBL233229 IC50 400.0 nM
N=C(N)n1cccn1 CHEMBL503356 Ki 400.0 nM
CN1CCCC(n2ccc3cc(NC(=N)c4ccco4)ccc32)CC1 CHEMBL3142301 IC50 400.0 nM
CN[C@H]1CC[C@@H](c2c[nH]c3ccc(NC(=N)c4cccs4)cc32)CC1 CHEMBL2036268 IC50 400.0 nM
C/N=C(/N)Nc1ccccc1CC(N)C(=O)O CHEMBL49881 Ki 410.0 nM
NC1=NCCS1 CHEMBL362148 Ki 410.0 nM
CN1CCC(n2ccc3cc(NC(=N)c4cccs4)ccc32)CC1 CHEMBL3216977 IC50 410.0 nM
CN(C)CCCc1c[nH]c2ccc(/N=C(\N)c3cccs3)cc12 CHEMBL3645466 IC50 410.0 nM
N/C(=N\c1ccc2c(c1)OCCN2CCN1CCCC1)c1cccs1 CHEMBL3675232 IC50 410.0 nM
CCCCN1CCC(N(C)Cc2cc(Cl)ccc2C#N)CC1 CHEMBL257008 IC50 420.0 nM
Cc1cc(N)nc(CCc2cncc(N(C)C)c2)c1 CHEMBL3819046 Ki 425.0 nM
CN(C)CCN1CCCc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3216313 IC50 430.0 nM
CN1CCC(N2CCc3cc(NC(=N)c4cccs4)ccc32)C1 CHEMBL3215677 IC50 430.0 nM
CN1CCC(c2c[nH]c3ccc(/N=C(\N)c4cccs4)cc23)C1 CHEMBL3645479 IC50 430.0 nM
CN1CCCC1CCN1CCOc2cc(/N=C(\N)c3cccs3)ccc21 CHEMBL3675230 IC50 430.0 nM
CCC[C@H]1CSCCC(N)=N1 CHEMBL186431 IC50 440.0 nM
O=c1cc(CN(Cc2ccccn2)c2cnccn2)c2ccc(F)c(F)c2[nH]1 CHEMBL1944885 IC50 440.0 nM
CN(C)CCN1CCCCc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3216322 IC50 440.0 nM
CCOc1ccc(Cc2nc3cc(NC(=N)c4cccs4)ccc3n2CCN(CC)CC)cc1 CHEMBL3216999 IC50 440.0 nM
Nc1ccc2ccc(CCNCCc3cccc(Cl)c3)cc2n1 CHEMBL3216851 Ki 440.0 nM
Nc1ccc2ccc(CCNCCc3cccc(Cl)c3)cc2n1 CHEMBL3736228 Ki 440.0 nM
Nc1ccc2ccc(CCNCCc3cccc(Cl)c3)cc2n1 CHEMBL3139682 Ki 440.0 nM
COc1ccnc(CSC)c1 CHEMBL1800523 pIC50 446.68 nM
NCCCC[C@H](NC(=O)[C@@H](N)CCC/N=C(\N)N[N+](=O)[O-])C(N)=O CHEMBL88107 Ki 450.0 nM
NCCCC[C@H](NC(=O)[C@@H](N)CCC/N=C(\N)N[N+](=O)[O-])C(N)=O CHEMBL1204423 Ki 450.0 nM
CCSC(=N)Nc1cccc(Cl)c1 CHEMBL552598 Ki 450.0 nM
CCSC(=N)Nc1cccc(Cl)c1 CHEMBL469352 Ki 450.0 nM
N=C(Nc1ccc2ccn(CCCN3CCCC3)c2c1)c1cccs1 CHEMBL3217168 IC50 450.0 nM
N=C(Nc1ccc2c(C3CN4CCC3CC4)c[nH]c2c1)c1cccs1 CHEMBL3142317 IC50 450.0 nM
NCCCNC(=O)[C@@H](N)CCC/N=C(\N)N[N+](=O)[O-] CHEMBL92493 Ki 460.0 nM
CCCC1CCCCC(N)=N1 CHEMBL553271 IC50 460.0 nM
CN(C)CCCn1ccc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3217185 IC50 470.0 nM
c1cncc(CN(CCCNCc2ccc3c(c2)OCO3)c2nc(-n3ccnc3)ns2)c1 CHEMBL1911998 EC50 480.0 nM
Cc1cc(N)nc(C#CCN2CC(F)(F)C2)c1 CHEMBL5192809 Ki 488.0 nM
Cc1cc(N)nc(CC(C)F)c1 CHEMBL450726 IC50 490.0 nM
N=C1CCCC(C[C@@H]2CNC[C@@H]2OCCNCCc2cccc(F)c2)N1 CHEMBL1270460 Ki 490.0 nM
N=C(Nc1ccc2ccn(CCN3CCCCC3)c2c1)c1cccs1 CHEMBL3216978 IC50 490.0 nM
CN[C@H]1CCC[C@@H](c2c[nH]c3ccc(NC(=N)c4cccs4)cc23)C1 CHEMBL2036272 IC50 490.0 nM
CNC1CCC(c2c[nH]c3ccc(/N=C(\N)c4cccs4)cc23)CC1 CHEMBL3645472 IC50 490.0 nM
N/C(=N\c1ccc2ccn(CCN3CCCCC3)c2c1)c1cccs1 CHEMBL1852369 IC50 490.0 nM
Nc1ccc2ccc(CNCCc3cccc(F)c3)cc2n1 CHEMBL3216616 Ki 493.0 nM
Nc1ccc2ccc(CNCCc3cccc(F)c3)cc2n1 CHEMBL3139371 Ki 493.0 nM
N=C(N)N(CCC[C@H](N)C(=O)O)[N+](=O)[O-] CHEMBL353794 IC50 500.0 nM
CCCC1CCCC(N)=N1 CHEMBL6760 IC50 500.0 nM
NC1=NC(C(F)(F)F)CCC1 CHEMBL267038 IC50 500.0 nM
Cc1ccc2c(c1)[C@H]1CCC[C@H]1C(N)=N2 CHEMBL83569 IC50 500.0 nM
N=C(Nc1ccc2nc(NC3CCN(Cc4ccccc4)CC3)sc2c1)c1cccs1 CHEMBL233857 IC50 500.0 nM
Cc1noc(C)c1C(=O)N(Cc1cc(=O)[nH]c2c(F)cccc12)c1cccc(Cl)c1 CHEMBL491727 EC50 500.0 nM
CN(C)c1cc(N(Cc2cc(=O)[nH]c3c(F)c(F)ccc23)c2cccc(Cl)c2)ncn1 CHEMBL1944890 IC50 500.0 nM
CNCc1cncc(OCc2ccc3ccc(N)nc3c2)c1 CHEMBL3736490 Ki 507.0 nM
Cc1cc(N)nc(CCC(C)C)c1 CHEMBL60372 IC50 510.0 nM
Cc1cc(N)nc(CCCF)c1 CHEMBL443862 IC50 514.0 nM
CNCCCc1cc(C#N)cc(CCc2cc(C)cc(N)n2)c1 CHEMBL4086997 Ki 516.0 nM
O=c1cc(Cn2c(C3CCC3)nc3ncccc32)c2ccc(F)c(F)c2[nH]1 CHEMBL1801495 EC50 520.0 nM
CN1CCCC(n2ccc3ccc(NC(=N)c4ccco4)cc32)CC1 CHEMBL3216281 IC50 520.0 nM
NC1=N[C@H]2CCCC[C@@H]2CC1 CHEMBL193007 IC50 530.0 nM
CN(Cc1cc(Cl)ccc1C#N)C1CCN(CC2CC2)CC1 CHEMBL256620 IC50 530.0 nM
CN1CCC(N(C)Cc2cc(Br)ccc2C#N)CC1 CHEMBL436643 IC50 530.0 nM
NCCNC(=O)[C@@H](N)CCC/N=C(\N)N[N+](=O)[O-] CHEMBL88267 Ki 540.0 nM
CN1CCC(N(C)Cc2cc(Cl)ccc2C#N)CC1 CHEMBL256249 IC50 540.0 nM
N=C(Nc1ccc2c(c1)CCCN2C1CCNCC1)c1cccs1 CHEMBL3217198 IC50 540.0 nM
N=C(Nc1ccc2c(c1)N(C1CCNCC1)CC2)c1cccs1 CHEMBL1955939 IC50 540.0 nM
CCN[C@H]1CC[C@@H](c2c[nH]c3ccc(NC(=N)c4cccs4)cc32)CC1 CHEMBL2036270 IC50 540.0 nM
CN1CC=C(c2c[nH]c3ccc(NC(=N)c4ccco4)cc23)CC1 CHEMBL3216551 IC50 550.0 nM
CCSC(=N)Nc1cccc(OC)c1 CHEMBL553216 Ki 560.0 nM
CCSC(=N)Nc1cccc(OC)c1 CHEMBL503085 Ki 560.0 nM
CNC1CCCC(c2c[nH]c3ccc(NC(=N)c4cccs4)cc23)C1 CHEMBL2036273 IC50 560.0 nM
CC(=N)Nc1ccc(C(=N)N)cc1 CHEMBL543380 Ki 570.0 nM
CSC(=N)Nc1ccc(Cl)cc1 CHEMBL538001 Ki 570.0 nM
CC(=N)Nc1cccc(C(=N)N)c1 CHEMBL463507 Ki 570.0 nM
COC(=O)[C@H](CCN)NC(=O)[C@@H](N)CCC/N=C(\N)N[N+](=O)[O-] CHEMBL317521 Ki 580.0 nM
CN(C)CCN1C(=O)CCc2cc(NC(=N)c3cccs3)ccc21 CHEMBL3216770 IC50 580.0 nM
NC1=Nc2c(F)cccc2[C@H]2CCC[C@@]12F CHEMBL350281 IC50 590.0 nM
CCC1CSCCC(N)=N1 CHEMBL185833 IC50 590.0 nM
CN1CCC(N(C)Cc2cc(Cl)ccc2Br)CC1 CHEMBL256069 IC50 590.0 nM
CCN(CC)CCCn1ccc2ccc(/N=C(\N)c3cccs3)cc21 CHEMBL1852460 IC50 590.0 nM
CNCCCc1cc(CCc2cc(C)cc(N)n2)cc(C(F)(F)F)c1 CHEMBL4065564 Ki 598.0 nM
CC(=N)Nc1ccc(CO)cc1 CHEMBL542431 Ki 600.0 nM
CC(C)CCN1CCC(N(C)Cc2cc(Cl)ccc2C#N)CC1 CHEMBL402425 IC50 600.0 nM
Cc1cc(N)nc(CC2CNCC2OCCNCCc2cccc(F)c2)c1 CHEMBL446971 IC50 600.0 nM
CCc1cnc(N)cc1C CHEMBL61599 IC50 610.0 nM
CC1CN=C(N)C1C CHEMBL185161 IC50 610.0 nM
CCC1CN=C(N)C1C CHEMBL184798 IC50 610.0 nM
C[C@H]1CC(N)=N[C@H]2CCCC[C@H]21 CHEMBL370922 IC50 610.0 nM
CC(C)c1nc2nccnc2n1Cc1cc(=O)[nH]c2c(F)c(F)ccc12 CHEMBL1801058 EC50 610.0 nM
CC(C)(C)SC(=N)N CHEMBL451408 Ki 620.0 nM
O=[N+]([O-])c1cccc2cn([N+](=O)[O-])nc12 CHEMBL593105 IC50 620.0 nM
N=C(Nc1ccc2c(c1)CCN2C(=O)CN1CCCC1)c1cccs1 CHEMBL3215676 IC50 620.0 nM
N=C(N)SCc1ccccc1 CHEMBL505665 Ki 630.0 nM
COc1ccc2c(c1)[C@H]1CCC[C@H]1C(N)=N2 CHEMBL85613 IC50 640.0 nM
N#Cc1ccc2c(c1)[C@H]1CCC[C@H]1C(N)=N2 CHEMBL83455 IC50 640.0 nM
CC(C)c1nc2ccccc2n1Cc1cc(=O)[nH]c2c(F)c(F)ccc12 CHEMBL1801482 EC50 650.0 nM
CC(C)CCc1nc2ccccc2n1Cc1cc(=O)[nH]c2c(F)c(F)ccc12 CHEMBL1801491 EC50 650.0 nM
O=c1cc(Cn2c(CC3CCC3)nc3ccccc32)c2ccc(F)c(F)c2[nH]1 CHEMBL1801493 EC50 650.0 nM
CN(C)Cc1cccc(NCc2ccc3ccc(N)nc3c2)c1 CHEMBL3735825 Ki 657.0 nM
CNCc1ccc2c(c1)N=C(N)[C@]1(F)CCC[C@H]21 CHEMBL354230 IC50 660.0 nM
CCSC(=N)Nc1ccc([N+](=O)[O-])cc1 CHEMBL543092 Ki 660.0 nM
NC1=NCC2CCCCC12 CHEMBL185441 IC50 660.0 nM
CCSC(=N)Nc1ccc([N+](=O)[O-])cc1 CHEMBL500141 Ki 660.0 nM
N=C(Nc1ccc2c(ccn2CCCN2CCOCC2)c1)c1cccs1 CHEMBL3216761 IC50 660.0 nM
N/C(=N\c1ccc2c(c1)SCCN2CCN1CCC[C@H]1C(=O)O)c1cccs1 CHEMBL3675246 IC50 660.0 nM
NC1=Nc2c(ccc(F)c2F)[C@H]2CCC[C@@H]12 CHEMBL86961 IC50 680.0 nM
N=C(NN)NO CHEMBL80352 Ki 680.0 nM
CCCc1nc2ccccc2n1Cc1cc(=O)[nH]c2c(F)c(F)ccc12 CHEMBL1801485 EC50 690.0 nM
CC(C)Cc1nc2ccccc2n1Cc1cc(=O)[nH]c2c(F)c(F)ccc12 CHEMBL1801490 EC50 690.0 nM
COC(=O)[C@@H](N)CCCNC(=N)N[N+](=O)[O-] CHEMBL1256014 IC50 690.0 nM
c1csc(CN(CCCNCc2ccc3c(c2)OCO3)c2nc(-n3ccnc3)ns2)c1 CHEMBL1912000 EC50 690.0 nM
CC1CCCN=C1N CHEMBL267167 IC50 700.0 nM
CCSC(=N)Nc1ccc(OC(F)(F)F)cc1 CHEMBL554651 Ki 700.0 nM
Cc1cc(N)nc(CC2CNCC2NCCNCCc2cccc(F)c2)c1 CHEMBL485160 IC50 700.0 nM
CCSC(=N)Nc1ccc(OC(F)(F)F)cc1 CHEMBL500922 Ki 700.0 nM
N=C(Nc1ccc2ccn(CCCN3CCOCC3)c2c1)c1cccs1 CHEMBL3216283 IC50 700.0 nM
N/C(=N\c1ccc2ccn(CCCN3CCOCC3)c2c1)c1cccs1 CHEMBL1852621 IC50 700.0 nM
CCNC1CCC(c2c[nH]c3ccc(/N=C(\N)c4cccs4)cc23)CC1 CHEMBL3645482 IC50 700.0 nM
O=[N+]([O-])c1cccc2cn[nH]c12 CHEMBL247378 IC50 710.0 nM
N=C(c1cccs1)N1CCC(c2c[nH]c3ccc(/N=C(\N)c4cccs4)cc23)CC1 CHEMBL3645471 IC50 717.0 nM
O=c1cc(Cn2c(C3CCC3)nc3ccncc32)c2ccc(F)c(F)c2[nH]1 CHEMBL1801497 EC50 730.0 nM
CCN[C@H]1CCC[C@@H](c2c[nH]c3ccc(NC(=N)c4cccs4)cc23)C1 CHEMBL2036275 IC50 730.0 nM
N#Cc1ccc(C(=O)N2CCC3(CC2)N=C(N)c2c(F)ccc(F)c2N3)cn1 CHEMBL447183 IC50 740.0 nM
CC[C@@H]1N=C(N)[Se][C@@H]1C CHEMBL178389 IC50 740.0 nM
CCOc1ccc(Cc2nc3cc(NC(=N)c4cccs4)ccc3n2CCN(C)C)cc1 CHEMBL3217000 IC50 740.0 nM
N#Cc1ccc(Cl)cc1CN(CC1CC1)C1CCNCC1 CHEMBL256618 IC50 748.0 nM
Fc1cccc(CCNCCc2ccnc(-n3ccnc3)n2)c1 CHEMBL3407809 Ki 758.0 nM
O=c1cc(Cn2c(C3CCC3)nc3c(Cl)ccnc32)c2ccc(F)c(F)c2[nH]1 CHEMBL1801500 EC50 760.0 nM
CN1C2CCC1CC(n1ccc3cc(NC(=N)c4cccs4)ccc31)C2 CHEMBL3215639 IC50 760.0 nM
CN(C)c1ccc(CNCc2ccc3ccc(N)nc3c2)cc1 CHEMBL4078323 Ki 764.0 nM
Nc1ccc2ccc(CNc3cccc(F)c3)cc2n1 CHEMBL4091981 Ki 768.0 nM
NC(=O)[C@H](CCC/N=C(/N)N[N+](=O)[O-])NC(=O)[C@@H](N)CCC/N=C(/N)N[N+](=O)[O-] CHEMBL1202117 Ki 770.0 nM
O=c1cc(Cn2c(C3CCCC3)nc3ccccc32)c2ccc(F)c(F)c2[nH]1 CHEMBL1801488 EC50 770.0 nM
CN1CCC(N(C)Cc2cc(Cl)ccc2C(F)(F)F)CC1 CHEMBL258348 IC50 780.0 nM
N=C(Nc1ccc2c(c1)CCC(=O)N2CCN1CCCCC1)c1cccs1 CHEMBL3216543 IC50 780.0 nM
CC[C@H]1[Se]C(N)=N[C@@H]1C CHEMBL178205 IC50 790.0 nM
Cc1cc(N)nc(CCNC(=O)c2ccc(C#N)cc2)c1 CHEMBL1221659 IC50 790.0 nM
CCSC(=N)Nc1ccncc1 CHEMBL542859 Ki 800.0 nM
CC1CN=C(N)C1 CHEMBL183012 IC50 800.0 nM
N=C(Nc1ccc2sc(NC3CCN(Cc4ccc(F)cc4)CC3)nc2c1)c1cccs1 CHEMBL233648 IC50 800.0 nM
CCSC(=N)Nc1ccncc1 CHEMBL510382 Ki 800.0 nM
N=C(N)SCCc1ccccc1 CHEMBL483093 Ki 800.0 nM
CN1CC=C(c2c[nH]c3cc(NC(=N)c4cccs4)ccc23)CC1 CHEMBL3142316 IC50 800.0 nM
COc1cc(-c2cccc(N)n2)c(OC)cc1CN(C)C CHEMBL360626 IC50 810.0 nM
CCCN1CCC(N(C)Cc2cc(Cl)ccc2C#N)CC1 CHEMBL272271 IC50 810.0 nM
CN1CCC(N2CCCc3cc(NC(=N)c4cccs4)ccc32)CC1 CHEMBL3217197 IC50 820.0 nM
CN1CCC[C@H]1Cc1c[nH]c2ccc(/N=C(\N)c3cccs3)cc12 CHEMBL3645476 IC50 820.0 nM
CC1CN=C(N)CCS1 CHEMBL187008 IC50 830.0 nM
CN(C)C1CC=C(c2c[nH]c3ccc(NC(=N)c4cccs4)cc23)CC1 CHEMBL2036264 IC50 840.0 nM
CN1CCC[C@@H]1Cc1c[nH]c2ccc(/N=C(\N)c3cccs3)cc12 CHEMBL3645475 IC50 840.0 nM
CCCCC1N=C(N)CC1C CHEMBL553119 IC50 850.0 nM
CCCCC1CCCCC(N)=N1 CHEMBL543514 IC50 850.0 nM
CCCCC1CCCCC(N)=N1 CHEMBL89288 IC50 850.0 nM
N/C(=N\c1ccc2c(c1)OCC(=O)N2CCN1CCCC1)c1cccs1 CHEMBL3675231 IC50 850.0 nM
CN(C)Cc1cccc(OCc2ccc3ccc(N)nc3c2)c1 CHEMBL3735617 Ki 855.0 nM
Cc1cc(N)nc(CCc2cncc(N3CCOCC3)c2)c1 CHEMBL3819644 Ki 862.0 nM
C=CCC1CCCCC(N)=N1 CHEMBL544693 IC50 870.0 nM
CN1CCCC(n2ccc3ccc(NC(=N)c4cccs4)cc32)CC1 CHEMBL3216955 IC50 870.0 nM
CN1CCCC(n2ccc3ccc(/N=C(\N)c4cccs4)cc32)CC1 CHEMBL1852496 IC50 870.0 nM
Fc1cccc(C[C@H]2C[C@@H]2NCCc2ccnc(-n3ccnc3)n2)c1 CHEMBL3407823 Ki 873.0 nM
Cc1cc(N)nc(C[C@H]2CNC[C@@H]2NCCNCCc2ccccc2)c1 CHEMBL1277786 Ki 880.0 nM
NCCCC[C@H](N)C(=O)N[C@H](CCC/N=C(\N)N[N+](=O)[O-])C(N)=O CHEMBL2092928 Ki 890.0 nM
Nc1nc(CCc2ccccc2)cs1 CHEMBL484101 Ki 890.0 nM
NC1=NC(Cc2ccccc2)CCC1 CHEMBL6875 IC50 900.0 nM
CC1CCN=C1N CHEMBL359703 IC50 900.0 nM
CNCc1cccc(OCc2ccc3ccc(N)nc3c2)c1 CHEMBL3736143 Ki 911.0 nM
CNCc1cccc(OCc2ccc3ccc(N)nc3c2)c1 CHEMBL3736586 Ki 911.0 nM
CN1CC=C(c2c[nH]c3ccc(/N=C(\N)c4cccs4)cc23)CC1 CHEMBL1963527 IC50 920.0 nM
NCCC1CCCCC(N)=N1 CHEMBL92475 IC50 932.0 nM
O=c1cc(Cn2c(CC3CC3)nc3ccccc32)c2ccc(F)c(F)c2[nH]1 CHEMBL1801492 EC50 950.0 nM
CNC(=N)NCCC[C@H](N)C(=O)O CHEMBL3217190 IC50 950.0 nM
CNC(=N)NCCC[C@H](N)C(=O)OC CHEMBL1956111 IC50 950.0 nM
CN[C@@H](CCCNC(=N)N)C(=O)O CHEMBL332148 IC50 950.0 nM
N/C(=N\c1ccc2[nH]cc(C3=CN4CCC3CC4)c2c1)c1cccs1 CHEMBL3645483 IC50 970.0 nM
Cc1cnccc1-c1nc2ccccc2n1Cc1cc(=O)[nH]c2c(F)c(F)ccc12 CHEMBL1801481 EC50 990.0 nM