C[C@H]1CC(N)=N[C@@H]2[C@H](Cl)[C@@H]21 CHEMBL105792 Ki 18.0 nM
C[C@H]1CC(N)=N[C@@H]2[C@H](Cl)[C@@H]21 CHEMBL1800346 pKi 18.62 nM
CC(C)SC(=N)N CHEMBL483091 Ki 22.0 nM
CCSC(=N)NCCC[C@H](N)C(=O)O CHEMBL106871 Ki 24.0 nM
N=C(NCCC[C@H](N)C(=O)O)N[N+](=O)[O-] CHEMBL227744 Ki 30.0 nM
CCCc1cc(C)cc(N)n1 CHEMBL302657 IC50 34.0 nM
CCSC(=N)N CHEMBL321691 Ki 39.0 nM
Cc1cc(C)nc(N)c1 CHEMBL59925 pIC50 44.67 nM
CCc1cc(C)cc(N)n1 CHEMBL294084 IC50 49.0 nM
NC1=NC(C2CC2)Cc2ccsc21 CHEMBL8365 IC50 50.0 nM
Cc1ccnc(N)c1 CHEMBL40833 IC50 72.0 nM
C#CC1Cc2ccsc2C(N)=N1 CHEMBL8292 IC50 80.0 nM
N=C(NCCC[C@H](N)CNCCN)N[N+](=O)[O-] CHEMBL227937 Ki 80.0 nM
C[C@H]1CN=C(N)c2sccc2O1 CHEMBL1221702 IC50 80.0 nM
Cc1ccnc(N)c1N CHEMBL61427 IC50 81.0 nM
Cc1cc(N)nc(C[C@H]2CNC[C@H]2NCCNCc2ccc(Cl)cc2)c1 CHEMBL474637 Ki 85.2 nM
Cc1cc(N)nc(C[C@H]2CNC[C@@H]2NCCNCc2cccc(Cl)c2)c1 CHEMBL526688 Ki 95.2 nM
N=C(NCCC[C@H](N)C(=O)N[C@@H](CCN)C(N)=O)N[N+](=O)[O-] CHEMBL44833 Ki 107.0 nM
NC(=O)[C@@H]1C[C@@H](NC(=O)[C@@H](N)CCC/N=C(\N)N[N+](=O)[O-])CN1 CHEMBL228077 Ki 110.0 nM
C#CC1Cc2sccc2C(N)=N1 CHEMBL8281 IC50 120.0 nM
CC1CCN=C(N)C1 CHEMBL6808 IC50 146.0 nM
Cc1ccnc(N)c1C CHEMBL61939 IC50 150.0 nM
Cc1cc(N)nc(CC(C)C)c1 CHEMBL294609 IC50 150.0 nM
NC1=NC(c2ccc(F)cc2)Cc2cccc(F)c21 CHEMBL7945 IC50 160.0 nM
NC1=NC(c2ccco2)Nc2c(F)ccc(F)c21 CHEMBL354788 IC50 180.0 nM
CN1CCC(N(C)Cc2cc(Cl)ccc2[N+](=O)[O-])CC1 CHEMBL272708 IC50 180.0 nM
Cc1cc(N)nc(C(C)C)c1 CHEMBL299677 IC50 200.0 nM
CCC[C@@H]1COc2ccsc2C(N)=N1 CHEMBL1221703 IC50 200.0 nM
CCC[C@H]1COc2ccsc2C(=N)N1 CHEMBL1230023 IC50 200.0 nM
CN(Cc1cc(Cl)ccc1C#N)C1CCN(CCc2ccccc2)CC1 CHEMBL428069 IC50 220.0 nM
CCc1ccnc(N)c1 CHEMBL62077 IC50 230.0 nM
CC1=CC(N)=NCC1 CHEMBL75304 IC50 230.0 nM
CC1=CC(N)=NC(C)C1 CHEMBL74919 IC50 240.0 nM
NC(N)=Nc1ccccc1CC(N)C(=O)O CHEMBL298404 Ki 250.0 nM
N=C(N)[C@H]1CCN1 CHEMBL1783094 IC50 250.0 nM
C/N=C(/N)Nc1ccccc1CC(N)C(=O)O CHEMBL49881 Ki 270.0 nM
NC1=NCCc2ccsc21 CHEMBL268521 IC50 280.0 nM
CNC(=N)NCCC[C@H](N)C(=O)O CHEMBL256147 IC50 300.0 nM
CC1CC(N)=NC(C)C1 CHEMBL269076 IC50 300.0 nM
CC1=C(C)C(N)=NCC1 CHEMBL75484 IC50 320.0 nM
CSCC(=N)Nc1cccc(CN)c1 CHEMBL555794 Ki 320.0 nM
N=C(Nc1cccc(CN)c1)c1ccco1 CHEMBL552825 Ki 350.0 nM
N=C(Nc1cccc(CN)c1)c1ccco1 CHEMBL96680 Ki 350.0 nM
C=CCC1CC(C)=CC(N)=N1 CHEMBL72316 IC50 360.0 nM
C[C@@H]1CC(N)=N[C@@H]2CCC[C@H]12 CHEMBL191242 IC50 360.0 nM
Nc1cccc(C[C@H]2CNC[C@H]2NCCCO)n1 CHEMBL475797 Ki 366.6 nM
CC(C)CN1CCN(CCc2ccc(-c3cccc(N)n3)cc2)CC1 CHEMBL86810 IC50 372.0 nM
N=C(Nc1cccc(CN)c1)c1cccs1 CHEMBL555715 Ki 400.0 nM
CCSC(=N)Nc1ccccc1 CHEMBL545673 Ki 400.0 nM
CSC(=N)NCCC[C@H](N)C(=O)O CHEMBL106516 IC50 400.0 nM
CCSC(=N)Nc1ccccc1 CHEMBL451666 Ki 400.0 nM
N=C(Nc1ccc2c(c1)CCN2CCN1CCCC1)c1cccs1 CHEMBL3215893 IC50 410.0 nM
NCCN[C@@H]1CNC[C@@H]1Cc1cccc(N)n1 CHEMBL510760 Ki 416.7 nM
Cn1cncc1C(=O)N(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cccc(Cl)c1 CHEMBL491923 EC50 420.0 nM
CC1=CCN=C(N)C1 CHEMBL76342 IC50 440.0 nM
Nc1cccc(-c2ccc(CCN3CCN(CCc4ccccc4)CC3)cc2)n1 CHEMBL87529 IC50 448.0 nM
NC1=NCCCOC1 CHEMBL362772 IC50 450.0 nM
CCN1CCC(N(C)Cc2cc(Cl)ccc2C#N)CC1 CHEMBL258310 IC50 450.0 nM
N=C(N)N(CCC[C@H](N)C(=O)O)[N+](=O)[O-] CHEMBL353794 IC50 500.0 nM
CC1=CC(N)=N[C@@H]2CCC[C@H]12 CHEMBL75428 IC50 510.0 nM
CC1=CC(N)=NCC1C CHEMBL75905 IC50 520.0 nM
CCC1N=C(N)CC1C CHEMBL185024 IC50 520.0 nM
CC(C)CCN1CCC(N(C)Cc2cc(Cl)ccc2C#N)CC1 CHEMBL402425 IC50 540.0 nM
CC(C)N(Cc1cc(Cl)ccc1C#N)C1CCNCC1 CHEMBL428248 IC50 570.0 nM
CCCC1CC(C)=CC(N)=N1 CHEMBL75496 IC50 580.0 nM
Cc1cnc(N)cc1C CHEMBL293022 IC50 600.0 nM
CC1CCCC(N)=N1 CHEMBL265672 IC50 600.0 nM
CC1CC(N)=NC1C CHEMBL185584 IC50 600.0 nM
N=C1CCCCN1 CHEMBL269058 IC50 630.0 nM
CNC(=N)NCCC[C@H](N)C(=O)O CHEMBL3217190 IC50 650.0 nM
CNC(=N)NCCC[C@H](N)C(=O)OC CHEMBL1956111 IC50 650.0 nM
CN[C@@H](CCCNC(=N)N)C(=O)O CHEMBL332148 IC50 650.0 nM
CCCSC(=N)N CHEMBL483092 Ki 670.0 nM
CCCCN1CCC(N(C)Cc2cc(Cl)ccc2C#N)CC1 CHEMBL257008 IC50 680.0 nM
COC(=O)[C@@H](N)CCCNC(=N)N[N+](=O)[O-] CHEMBL1256014 IC50 680.0 nM
Nc1cccc(-c2ccc(CCN3CCN(C(=O)Cc4ccccc4)CC3)cc2)n1 CHEMBL87544 IC50 685.0 nM
N=C(Nc1ccc2nc(NC3CCN(CCc4cnc[nH]4)CC3)sc2c1)c1cccs1 CHEMBL233653 IC50 700.0 nM
NC1=NC(C2CC2)Cc2sccc21 CHEMBL8105 IC50 750.0 nM
CN1CCC(N(C)Cc2cc(Cl)ccc2C#N)CC1 CHEMBL256249 IC50 770.0 nM
N=C(Nc1ccc2c(c1)CCN2C(=O)CN1CCCC1)c1cccs1 CHEMBL3215676 IC50 770.0 nM
Nc1cccc(-c2ccc(OCCN3CCCC3)c3c2CCC3)n1 CHEMBL290476 IC50 785.0 nM
CC(=N)NCCC[C@H](N)C(=O)O CHEMBL11471 Ki 810.0 nM
CN1CCC(N(C)Cc2cc(Br)ccc2C#N)CC1 CHEMBL436643 IC50 810.0 nM
CC(C)NC(=O)CN1CCN(CCc2ccc(-c3cccc(N)n3)cc2)CC1 CHEMBL87186 IC50 815.0 nM
Cc1cccc(N)n1 CHEMBL61591 IC50 820.0 nM
CN1CCC(N(C)Cc2cc(Cl)ccc2Br)CC1 CHEMBL256069 IC50 820.0 nM
Nc1cccc(-c2ccc(CCN3CCN(c4cccc5cccnc45)CC3)cc2)n1 CHEMBL87187 IC50 825.0 nM
C[C@@H]1CC(N)=N[C@@H]2CCCC[C@H]12 CHEMBL191675 IC50 830.0 nM
CN(Cc1cc(Cl)ccc1C#N)C1CCN(CC2CC2)CC1 CHEMBL256620 IC50 860.0 nM
C[C@H]1CC(N)=N[C@H]2CCC[C@H]21 CHEMBL433589 IC50 870.0 nM
Nc1cccc(-c2ccc(CCN3CCN(CC(=O)c4ccccc4)CC3)cc2)n1 CHEMBL40391 IC50 887.0 nM
N=C(N)NCCC[C@H](N)C(=O)O CHEMBL1485 Km 900.0 nM
C#CC1Cc2ccccc2C(N)=N1 CHEMBL8272 IC50 900.0 nM
CCSC(=N)Nc1ccc(Cl)cc1 CHEMBL543806 Ki 900.0 nM
N=C(Nc1ccc2nc(NCCc3ccccn3)sc2c1)c1cccs1 CHEMBL233652 IC50 900.0 nM
NC1=NC(c2ccco2)Cc2ccsc21 CHEMBL274405 IC50 920.0 nM
NC1=Nc2ccccc2[C@H]2COC[C@@H]12 CHEMBL315966 IC50 960.0 nM
CN(Cc1cc(Cl)ccc1C#N)C1CCCNC1 CHEMBL271248 IC50 983.0 nM
COc1ccnc(N)c1 CHEMBL113793 IC50 1000.0 nM
CCSC(=N)Nc1ccc(C)cc1 CHEMBL543098 Ki 1000.0 nM
CCC[C@H]1CSCCC(N)=N1 CHEMBL186431 IC50 1000.0 nM
CCN(Cc1cc(Cl)ccc1C#N)C1CCNCC1 CHEMBL403952 IC50 1000.0 nM