COc1cc(-c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)ccc1O CHEMBL441558 IC50 10.0 nM
CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](N)CCC(=O)O)C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)O)C(C)C CHEMBL5435186 IC50 19.0 nM
CN1c2ccccc2Sc2cc(N)ccc21 CHEMBL1323615 IC50 44.0 nM
CN(C)c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1 CHEMBL1567692 IC50 48.0 nM
CC(=NNc1ccc(C(=O)O)cc1)c1ccc2c(c1)Nc1ccccc1S2 CHEMBL1331532 IC50 53.0 nM
CCOC(=O)Nc1ccc2c(c1)Nc1ccccc1S2 CHEMBL1401860 IC50 54.0 nM
CSc1ccc(NC(=O)Nc2ccc(N(C)C)cc2)cc1 CHEMBL1394104 IC50 77.66 nM
CCN(CC)c1ccc(NC(=O)Nc2cccc(C(C)=O)c2)cc1 CHEMBL1350157 IC50 83.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCN(Cc1ccccc1Cl)C3 CHEMBL1927149 Ki 87.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCN(Cc1ccc(Cl)cc1)C3 CHEMBL1927151 Ki 95.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCN(Cc1ccccc1)C3 CHEMBL1927147 Ki 101.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCN(Cc1cccc(Cl)c1)C3 CHEMBL1927150 Ki 104.0 nM
COc1cccc(CN2CCCn3c(c4c(=O)n(-c5ccccc5Cl)[nH]c4cc3=O)C2)c1 CHEMBL1927153 Ki 113.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCN(Cc1ccccn1)C3 CHEMBL1927157 Ki 113.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCNC3 CHEMBL1927146 Ki 119.0 nM
CC(=O)c1ccc2c(c1)Nc1ccccc1S2 CHEMBL407734 IC50 128.6 nM
COc1ccccc1CN1CCCn2c(c3c(=O)n(-c4ccccc4Cl)[nH]c3cc2=O)C1 CHEMBL1927152 Ki 133.0 nM
CN(C)c1cccc(-c2c3c(=O)n(-c4ccccc4Cl)[nH]c3cc(=O)n2C)c1 CHEMBL4303187 Ki 140.0 nM
CC(C)(C)OC(=O)N1CCCn2c(c3c(=O)n(-c4ccccc4Cl)[nH]c3cc2=O)C1 CHEMBL1927145 Ki 148.0 nM
COc1ccc(NC(=O)Nc2ccc(N(C)C)cc2)cc1 CHEMBL1449547 IC50 156.0 nM
Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1Cc1ccccn1 CHEMBL1276946 Ki 165.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCOC3 CHEMBL1927160 Ki 173.0 nM
CCN(CC)c1ccc(NC(=O)Nc2ccccc2)cc1 CHEMBL1377821 IC50 176.0 nM
COc1ccc2c(c1)Sc1ccc(Cl)cc1N2 CHEMBL1472573 IC50 176.9 nM
COc1ccc(CN2CCCn3c(c4c(=O)n(-c5ccccc5Cl)[nH]c4cc3=O)C2)cc1 CHEMBL1927154 Ki 184.0 nM
CN(C)c1ccc(NC(=O)Nc2ccc3snnc3c2)cc1 CHEMBL1330018 IC50 187.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCN(Cc1ccoc1)C3 CHEMBL1927155 Ki 200.0 nM
CN1c2ccc(N)cc2Sc2cc(C(=O)c3ccccc3)ccc21 CHEMBL1395104 IC50 201.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCN(Cc1cccnc1)C3 CHEMBL1927156 Ki 208.0 nM
COc1cccc(CN2CCCn3c(c4c(=O)n(-c5ccccc5OC)[nH]c4cc3=O)C2)c1 CHEMBL1927159 Ki 212.0 nM
COc1ccccc1-n1[nH]c2cc(=O)n3c(c2c1=O)CN(Cc1ccccn1)CCC3 CHEMBL1927158 Ki 217.0 nM
COc1ccccc1-n1[nH]c2cc(=O)n3c(c2c1=O)CN(Cc1ccccc1)CCC3 CHEMBL1927148 Ki 218.0 nM
Fc1ccc(NC(=S)NNC(=S)Nc2ccccc2)cc1 CHEMBL1550870 IC50 218.2 nM
CN(C)c1ccc(NC(=O)Nc2ccc(OCc3ccccc3)cc2)cc1 CHEMBL1473456 IC50 230.0 nM
CCN(CC)c1ccc(NC(=O)Nc2ccc(OCc3ccccc3)cc2)cc1 CHEMBL1397941 IC50 235.3 nM
Fc1ccc2c(c1)Sc1ccccc1N2 CHEMBL1553680 IC50 239.7 nM
c1ccc2c(c1)[I+]c1ccccc1-2 CHEMBL397686 IC50 240.0 nM
CSc1ccc2c(c1)Nc1ccccc1S2 CHEMBL1354612 IC50 240.9 nM
CCN(CC)c1ccc(NC(=O)Nc2ccc(C(C)=O)cc2)cc1 CHEMBL1526463 IC50 252.0 nM
Clc1ccc2c(c1)Nc1ccccc1S2 CHEMBL1411769 IC50 253.5 nM
CC(=NNc1cccc(C(=O)O)c1)c1ccc2c(c1)Nc1ccccc1S2 CHEMBL1353985 IC50 305.0 nM
FC(F)(F)c1ccc2c(c1)Nc1ccccc1S2 CHEMBL541018 IC50 320.0 nM
S=C(NNC(=S)Nc1ccccc1)Nc1ccccc1 CHEMBL1342313 IC50 320.5 nM
c1ccc2c(c1)Nc1ccccc1S2 CHEMBL828 IC50 349.0 nM
CN1C(=S)N(c2cccc(Cl)c2)C(=O)/C1=C/c1ccc(N(C)C)cc1 CHEMBL3827985 Ki 350.0 nM
CCN(CC)c1ccc(NC(=O)Nc2ccccc2C(F)(F)F)cc1 CHEMBL1404241 IC50 354.0 nM
c1ccc2c(c1)Nc1nc3ccccc3nc1N2 CHEMBL1489079 IC50 360.0 nM
CC(O)c1ccc2c(c1)Nc1ccccc1S2 CHEMBL1354139 IC50 363.5 nM
CC(=NNC(=O)c1ccc(O)cc1)c1ccc2c(c1)Nc1ccccc1S2 CHEMBL1408679 IC50 382.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCN(Cc1ccccc1)C3 CHEMBL1926690 Ki 398.0 nM
CC1=C(O)C(=O)C=C2C1=CC=C1[C@@]2(C)CC[C@@]2(C)[C@@H]3C[C@](C)(C(=O)O)CC[C@]3(C)CC[C@]12C CHEMBL301982 IC50 410.0 nM
Oc1c(Br)cc(/C=N/Nc2c(Cl)cncc2Cl)cc1Br CHEMBL1315444 IC50 429.6 nM
CN(C)c1ccc(/C=N/Nc2c(Cl)cncc2Cl)cc1 CHEMBL1517979 IC50 440.0 nM
CN(C)c1ccc(NC(=O)Nc2cccc3ccccc23)cc1 CHEMBL1331887 IC50 464.0 nM
O=c1c2ccccc2[se]n1-c1ccccc1 CHEMBL51085 IC50 500.0 nM
c1ccc(Cn2nnc3c(Sc4nc5ccccc5o4)ncnc32)cc1 CHEMBL4210329 IC50 500.0 nM
COc1cc(-c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)cc(OC)c1O CHEMBL587104 IC50 516.9 nM
CC(=NNc1ccc(C(=O)O)cc1)c1ccc2c(c1)Nc1ccccc1S2 CHEMBL1394037 IC50 561.0 nM
O=C(Nc1c(F)cccc1F)N1c2ccccc2Sc2ccccc21 CHEMBL1434402 IC50 635.6 nM
CN1c2ccccc2Sc2cc(NC(=O)CCl)ccc21 CHEMBL1552577 IC50 652.9 nM
Cc1cc(Cl)ccc1NC(=S)NNC(=S)Nc1ccc(F)cc1 CHEMBL1434771 IC50 670.0 nM
S=C(NNC(=S)Nc1ccc(Cl)cc1)Nc1ccccc1 CHEMBL1589810 IC50 725.1 nM
CN1c2ccccc2Sc2cc(N=[N+]=[N-])ccc21 CHEMBL1434086 IC50 730.0 nM
COc1ccc2c(c1)Nc1ccccc1S2 CHEMBL64404 IC50 912.7 nM
COc1ccc2c(c1)Sc1ccccc1N2 CHEMBL1331821 IC50 935.5 nM
CC(=O)c1ccc2c(c1)N(C)c1ccccc1S2 CHEMBL1362864 IC50 1000.0 nM