Oc1ccccc1-c1nc(-c2ccc(C(F)(F)F)cc2)no1 CHEMBL4859206 IC50 10.71 nM
Oc1ccccc1-c1nc(-c2ccccc2)no1 CHEMBL1876217 IC50 16.4 nM
Oc1ccccc1-c1nc(Cc2ccccc2)no1 CHEMBL4849098 IC50 21.94 nM
CN(Cc1ccccc1)Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1Cc1ccn(C)n1 CHEMBL1277852 Ki 47.0 nM
COc1cccc(N2CCN(Cc3c4c(=O)n(-c5ccccc5Cl)[nH]c4cc(=O)n3C)CC2)c1 CHEMBL1277767 Ki 65.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCN(Cc1ccccn1)C3 CHEMBL1927157 Ki 67.0 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 70.77 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCN(Cc1ccccc1)C3 CHEMBL1927147 Ki 72.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCN(Cc1ccccc1Cl)C3 CHEMBL1927149 Ki 76.0 nM
Cn1c(COCc2ccccc2Cl)c2c(=O)n(-c3ccccc3Cl)[nH]c2cc1=O CHEMBL1277933 Ki 82.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCNC3 CHEMBL1927146 Ki 87.0 nM
c1ccc2c(c1)[I+]c1ccccc1-2 CHEMBL397686 IC50 90.0 nM
COc1ccccc1-n1[nH]c2cc(=O)n3c(c2c1=O)CN(Cc1ccccn1)CCC3 CHEMBL1927158 Ki 93.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCN(Cc1cccnc1)C3 CHEMBL1927156 Ki 94.0 nM
O=c1c2c(COCc3ccccc3)n(Cc3cnccn3)c(=O)cc2[nH]n1-c1ccccc1Cl CHEMBL1277853 Ki 95.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCN(Cc1cccc(Cl)c1)C3 CHEMBL1927150 Ki 101.0 nM
CC(C)(C)OC(=O)N1CCCn2c(c3c(=O)n(-c4ccccc4Cl)[nH]c3cc2=O)C1 CHEMBL1927145 Ki 103.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCN(Cc1ccc(Cl)cc1)C3 CHEMBL1927151 Ki 103.0 nM
CN(C)c1cccc(-c2c3c(=O)n(-c4ccccc4Cl)[nH]c3cc(=O)n2C)c1 CHEMBL4303187 Ki 110.0 nM
COc1ccccc1CN1CCCn2c(c3c(=O)n(-c4ccccc4Cl)[nH]c3cc2=O)C1 CHEMBL1927152 Ki 111.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCN(Cc1ccoc1)C3 CHEMBL1927155 Ki 111.0 nM
COc1cccc(CN2CCCn3c(c4c(=O)n(-c5ccccc5Cl)[nH]c4cc3=O)C2)c1 CHEMBL1927153 Ki 112.0 nM
O=c1c2c(CN3CCCC3)n(CCc3ccccn3)c(=O)cc2[nH]n1-c1ccc(F)cc1Cl CHEMBL1277676 Ki 114.0 nM
Cn1c(COc2ccc(F)cc2)c2c(=O)n(-c3ccccc3Cl)[nH]c2cc1=O CHEMBL1277934 Ki 114.0 nM
COc1ccc(CN2CCCn3c(c4c(=O)n(-c5ccccc5Cl)[nH]c4cc3=O)C2)cc1 CHEMBL1927154 Ki 116.0 nM
Cn1c(-c2ccccc2F)c2c(=O)n(-c3ccccc3Cl)[nH]c2cc1=O CHEMBL1278018 Ki 128.0 nM
COc1cccc(CN2CCCn3c(c4c(=O)n(-c5ccccc5OC)[nH]c4cc3=O)C2)c1 CHEMBL1927159 Ki 131.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCN(Cc1ccccc1)C3 CHEMBL1926690 Ki 142.0 nM
COc1ccccc1-n1[nH]c2cc(=O)n3c(c2c1=O)CN(Cc1ccccc1)CCC3 CHEMBL1927148 Ki 144.0 nM
CN(Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1Cc1ccncc1)c1ccccc1 CHEMBL1277677 Ki 151.0 nM
COCCn1c(COc2ccc(F)cc2)c2c(=O)n(CCN3CCOCC3)[nH]c2cc1=O CHEMBL1277583 Ki 153.0 nM
O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCOC3 CHEMBL1927160 Ki 156.0 nM
Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1CC#Cc1ccccc1 CHEMBL1278200 Ki 158.0 nM
Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1Cc1ccccn1 CHEMBL1276946 Ki 165.0 nM
COCCCn1c(CN(C)Cc2ccccc2)c2c(=O)n(-c3ccc(F)cc3Cl)[nH]c2cc1=O CHEMBL1277582 Ki 165.0 nM
O=c1c2cc(O)c(O)cc2c2cc(O)c(O)cc2n1Cc1cc([N+](=O)[O-])ccc1O CHEMBL1242941 IC50 170.0 nM
CN(Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1CCc1ccccn1)c1ccccc1 CHEMBL1277768 Ki 172.0 nM
Cc1ccccc1-n1[nH]c2cc(=O)n(Cc3ccccn3)c(C)c2c1=O CHEMBL1277489 Ki 173.0 nM
Cc1c2c(=O)n(-c3ccc(F)cc3Cl)[nH]c2cc(=O)n1C CHEMBL1277932 Ki 213.0 nM
Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1C CHEMBL1276162 Ki 215.0 nM
Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1NC(=O)COc1ccc(F)cc1 CHEMBL1276857 Ki 218.0 nM
Cc1c2c(=O)n(Cc3cc(Cl)ccc3Cl)[nH]c2cc(=O)n1Cc1ccccn1 CHEMBL1277215 Ki 218.0 nM
Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1CCN(C)C CHEMBL1278111 Ki 235.0 nM
Cc1c2c(=O)n(-c3ccc(F)cc3Cl)[nH]c2cc(=O)n1Cc1ccccn1 CHEMBL1277399 Ki 235.0 nM
Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1Cc1cccc(N2CCOCC2)n1 CHEMBL1277032 Ki 236.0 nM
Nc1cccc(Nc2ncnc3c2sc2ccc(N)cc23)c1 CHEMBL1243033 IC50 240.0 nM
CC(=O)n1c2cc(=O)n(Cc3cccnc3)c(C)c2c(=O)n1-c1ccccc1Cl CHEMBL1277850 Ki 240.0 nM
Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1Cc1ccc(S(N)(=O)=O)cc1 CHEMBL1276945 Ki 259.0 nM
Cc1c2c(=O)n(Cc3ccc(Cl)cc3)[nH]c2cc(=O)n1Cc1ccccn1 CHEMBL1277398 Ki 259.0 nM
O=c1c2cc(O)c(O)cc2c2cc(O)c(O)cc2n1Cc1cccc([N+](=O)[O-])c1 CHEMBL1242942 IC50 260.0 nM
COc1cccc(CC(=O)n2c3cc(=O)n(Cc4cccnc4)c(C)c3c(=O)n2-c2ccccc2)c1 CHEMBL1277765 Ki 285.0 nM
Cc1c2c(=O)n(-c3cccc(C#N)c3)[nH]c2cc(=O)n1C CHEMBL1278017 Ki 293.0 nM
Cc1c2c(=O)n(-c3ccccc3F)[nH]c2cc(=O)n1C CHEMBL1276163 Ki 308.0 nM
COCCn1[nH]c2cc(=O)n(Cc3ccccn3)c(C)c2c1=O CHEMBL1277033 Ki 313.0 nM
Cc1c2c(=O)n(CCOc3ccc(Cl)cc3)[nH]c2cc(=O)n1Cc1ccccn1 CHEMBL1277214 Ki 326.0 nM
CC(=O)Nc1cccc(-n2[nH]c3cc(=O)n(C)c(C)c3c2=O)c1 CHEMBL1275631 Ki 328.0 nM
Cc1c2c(=O)n(CCc3ccccc3)[nH]c2cc(=O)n1Cc1ccccn1 CHEMBL1277124 Ki 334.0 nM
Cc1c2c(=O)n(-c3cccc(Cl)c3)[nH]c2cc(=O)n1C CHEMBL1276222 Ki 340.0 nM
Cc1c2c(=O)n(Cc3ccc(F)cc3Cl)[nH]c2cc(=O)n1Cc1ccccn1 CHEMBL1277310 Ki 342.0 nM
Cc1c2c(=O)n(-c3ccccc3)[nH]c2cc(=O)n1Cc1cccnc1 CHEMBL1277122 Ki 373.0 nM
Cc1c2c(=O)n(C)[nH]c2cc(=O)n1Cc1ccccn1 CHEMBL1276223 Ki 387.0 nM
CC(=O)n1c2cc(=O)n(Cc3cccnc3)c(C)c2c(=O)n1-c1ccccc1C CHEMBL1277766 Ki 398.0 nM
CC(=O)n1c2cc(=O)n(Cc3cccnc3)c(C)c2c(=O)n1-c1ccccc1 CHEMBL1277397 Ki 409.0 nM
Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1CCCC(=O)N1CCN(C)CC1 CHEMBL1278199 Ki 428.0 nM
Cc1c2c(=O)n(CCN3CCOCC3)[nH]c2cc(=O)n1Cc1ccccn1 CHEMBL1277123 Ki 445.0 nM
Cc1c2c(=O)n(-c3ccnc4cc(Cl)ccc34)[nH]c2cc(=O)n1Cc1ccccn1 CHEMBL1277490 Ki 458.0 nM
Cc1c2c(=O)n(Cc3ccccc3)[nH]c2cc(=O)n1Cc1ccccn1 CHEMBL1277309 Ki 463.0 nM
COc1ccc(S(=O)(=O)N2CCN(c3ccc(C(F)(F)F)cc3)C2=O)cc1 CHEMBL4208156 IC50 500.0 nM
Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1Cc1ccc(CN2CCN(C)CC2)cc1 CHEMBL1276858 Ki 515.0 nM
Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1CC1CCCCC1 CHEMBL1278109 Ki 520.0 nM
Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1CCCO CHEMBL1278110 Ki 565.0 nM
N#Cc1ccccc1Cn1c(=O)c2cc(O)c(O)cc2c2cc(O)c(O)cc21 CHEMBL1242968 IC50 590.0 nM
CC(C)c1cc(/C=C2\C(=O)Nc3ccccc32)cc(C(C)C)c1O CHEMBL85021 IC50 630.0 nM
CCCc1c(-c2ccccc2)nn(-c2ccccn2)c1O CHEMBL4650894 Ki 630.0 nM
O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL50 IC50 680.0 nM
Cc1ccc(N2CCN(c3nc(N)nc(Nc4ccc(C)c(C)c4)n3)CC2)cc1 CHEMBL5218591 IC50 680.0 nM
Cc1ccc(N2CCN(Cc3nc(N)nc(Nc4ccc(C)c(C)c4)n3)CC2)cc1 CHEMBL5398181 IC50 680.0 nM
COc1cc(O)cc2oc(-c3ccc(O)c(O)c3)c(O)c(=O)c12 CHEMBL470848 IC50 740.0 nM
O=c1c(-c2ccc(O)c(O)c2)c(O)oc2cc(O)ccc12 CHEMBL1243032 IC50 790.0 nM
O=c1c(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL1098724 IC50 830.0 nM
CN1C(=S)N(c2cccc(Cl)c2)C(=O)/C1=C/c1ccc(N(C)C)cc1 CHEMBL3827985 Ki 840.0 nM
O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL151 IC50 850.0 nM
Cc1c2c(=O)n(-c3ccc(F)cc3)[nH]c2cc(=O)n1Cc1ccccc1 CHEMBL1277308 Ki 878.0 nM
CN1C(=S)N(c2ccccc2)C(=O)/C1=C/c1ccc(N(C)C)cc1 CHEMBL3827795 Ki 880.0 nM
O=C(N/N=C/c1cccc(O)c1O)C(=O)N/N=C/c1cccc(O)c1O CHEMBL1243187 IC50 910.0 nM
O=C(O)c1cc(NCc2ccccc2O)ccc1O CHEMBL131407 IC50 960.0 nM
C=CCN(CC=C)C(=S)/N=C1\C(=O)Nc2cc(C)c(O)c(C)c21 CHEMBL1243064 IC50 1000.0 nM