Cc1c(C)c(C)c(S(=O)(=O)Nc2ccc3c(c2)ncn3Cc2ccccc2)c(C)c1C CHEMBL463678 EC50 0.7 nM
CCC[C@H](C)Oc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(OC)ccc2OC)c1C CHEMBL5284539 IC50 1.0 nM
Cc1cc(C)c(S(=O)(=O)Nc2ccc3c(c2)ncn3Cc2ccccc2)c(C)c1 CHEMBL464497 EC50 1.5 nM
CCCC(C)Oc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(OC)ccc2OC)c1C CHEMBL5286515 IC50 1.6 nM
CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)O CHEMBL8739 EC50 2.0 nM
C/C=C1\C(=O)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL410683 IC50 2.4 nM
C/C=C1/C(=O)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL402063 IC50 2.4 nM
O=S(=O)(c1ccccc1)N(CC(F)(F)F)c1ccc(C(O)(C2CCCCC2)C(F)(F)F)cc1 CHEMBL396952 Log EC50 3.162 nM
N[C@H](C(=O)O)[C@H](O)c1ccc(O)c(O)c1 CHEMBL2103827 EC50 4.0 nM
CCC[C@H](C)Oc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(C)ccc2OC)c1C CHEMBL5277255 IC50 4.0 nM
CCS(=O)(=O)c1ccc(CNC(=O)N2C[C@@H](c3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)[C@@](C)(c3ccc(F)cc3)C2)cc1 CHEMBL4785075 EC50 5.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(Br)ccc2OC)c1C CHEMBL5290088 IC50 6.9 nM
CCCC(C)Oc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(C)ccc2OC)c1C CHEMBL5281952 IC50 6.9 nM
CCC(C)COc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(OC)ccc2OC)c1C CHEMBL5282848 IC50 7.0 nM
CCC[C@H](C)Oc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(Cl)ccc2OC)c1C CHEMBL5285451 IC50 7.0 nM
O=S(=O)(c1ccccc1)N(CC(F)(F)F)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL62136 EC50 8.0 nM
CC(C)(O)c1ccc(N(CC(F)(F)F)S(=O)(=O)c2ccccc2)cc1 CHEMBL3781118 EC50 8.0 nM
CCC[C@@H](C)Oc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(C)ccc2OC)c1C CHEMBL5274748 EC50 8.1 nM
O=S(=O)(c1ccccc1)N(CC(F)(F)F)c1ccc(C(O)(C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)F)cc1 CHEMBL430006 Log EC50 10.0 nM
O=S(=O)(c1ccc(F)cc1)C1(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)CCCC1 CHEMBL4591380 EC50 10.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3cc(C(C)(C)C)ccc3OCCC(C)C)c2C)c1 CHEMBL5288280 IC50 12.0 nM
CCCCCCn1cnc2cc(NS(=O)(=O)c3c(C)c(C)c(C)c(C)c3C)ccc21 CHEMBL465733 EC50 13.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(C)ccc2OC)c1C CHEMBL5274800 IC50 14.0 nM
CCC[C@@H](C)Oc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(OC)ccc2OC)c1C CHEMBL5286999 IC50 14.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3cc(-c4ccccc4)cc(C(C)(C)C)c3)c2C)c1 CHEMBL5284102 IC50 14.0 nM
CCC[C@@H](C)Oc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(Cl)ccc2OC)c1C CHEMBL5277006 IC50 15.0 nM
CCCC(C)Oc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(Cl)ccc2OC)c1C CHEMBL5289969 IC50 15.0 nM
O=S(=O)(c1ccccc1)N(CC(F)(F)F)c1ccc(C(O)(c2ccccc2)C(F)(F)F)cc1 CHEMBL242293 Log EC50 15.85 nM
CC1CCN(S(=O)(=O)c2ccc(F)cc2)c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc21 CHEMBL4209665 EC50 16.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(Cl)ccc2OC)c1C CHEMBL5269977 IC50 16.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(OC)ccc2Cl)c1C CHEMBL5290100 IC50 16.0 nM
CN1CCN(S(=O)(=O)c2ccc(F)cc2)c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc21 CHEMBL4217418 EC50 18.0 nM
O=S(=O)(Nc1ccc2c(c1)ncn2Cc1ccccc1)c1cccc2ccccc12 CHEMBL457270 EC50 20.0 nM
O=S(=O)(Nc1ccc2c(c1)ncn2Cc1ccccc1)c1ccccc1Br CHEMBL464867 EC50 20.0 nM
O=S(=O)(c1ccc(F)cc1)N1CCSc2cc(C(O)(C(F)(F)F)C(F)(F)F)ccc21 CHEMBL4210791 EC50 20.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(OC)ccc2OC)c1C CHEMBL5276468 IC50 22.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(F)ccc2OC)c1C CHEMBL5271698 IC50 22.0 nM
COc1ccc(OC)c(-n2nnc(S(=O)(=O)Nc3ccc(C(C)(C)C)cc3)c2C)c1 CHEMBL5316222 IC50 22.0 nM
O=S(=O)(Nc1ccc2c(c1)ncn2Cc1ccccc1)c1ccccc1Cl CHEMBL513946 EC50 23.0 nM
COc1ccc(OC)c(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C)c1 CHEMBL4863215 IC50 24.0 nM
O=S(=O)(c1ccc(F)cc1)N1CCCc2cc(C(O)(C(F)(F)F)C(F)(F)F)ccc21 CHEMBL4212458 EC50 25.0 nM
CC(C)=CCC[C@]1(C)[C@@H](CC=C(C)C)C[C@@]2(CC=C(C)C)C(=O)[C@]1(C(=O)C(C)C)C(=O)C(CC=C(C)C)=C2O CHEMBL501711 Ki 27.0 nM
CCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(OC)ccc2OC)c1C CHEMBL5291207 IC50 27.0 nM
CCCCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(OC)ccc2OC)c1C CHEMBL5277482 IC50 27.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2ccccc2OC)c1C CHEMBL5280042 IC50 28.0 nM
Cc1cc(C)cc(S(=O)(=O)Nc2ccc3c(c2)ncn3Cc2ccccc2)c1 CHEMBL464496 EC50 33.0 nM
CC1(C)CCN(S(=O)(=O)c2ccc(F)cc2)c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc21 CHEMBL4206412 EC50 36.0 nM
CCN(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)S(=O)(=O)c1ccccc1 CHEMBL2326845 EC50 39.0 nM
CCCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(OC)ccc2OC)c1C CHEMBL5288757 IC50 39.0 nM
CCCCNc1cc(NC(=O)c2nnn(-c3cc(OC)ccc3OC)c2C)cc(C(C)(C)C)c1 CHEMBL5277632 IC50 39.0 nM
CC(C)=CCC1=C(O)[C@@]2(C(=O)C(C)C)C(=O)[C@](CC=C(C)C)(C[C@H](CC=C(C)C)[C@@]2(C)CCC=C(C)C)C1=O CHEMBL1237210 EC50 40.0 nM
CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc3c(c2)ncn3Cc2ccccc2)cc1 CHEMBL463679 EC50 42.0 nM
Cc1ccccc1S(=O)(=O)Nc1ccc2c(c1)ncn2Cc1ccccc1 CHEMBL517474 EC50 45.0 nM
CCC(O)(c1ccc(C2(S(=O)(=O)c3ccc(F)cc3)CCCC2)cc1)C(F)(F)F CHEMBL4444851 EC50 48.0 nM
CC(c1ccccc1)n1cnc2cc(NS(=O)(=O)Cc3ccccc3Cl)ccc21 CHEMBL457271 EC50 49.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3cc(C(C)(C)C)cc(C(C)(C)C)c3)c2C)c1 CHEMBL5276535 IC50 49.0 nM
COc1ccc(Br)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4857525 IC50 50.0 nM
COc1ccc(C#N)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4846228 IC50 50.0 nM
O=S(=O)(Nc1ccc2c(c1)ncn2Cc1ccccc1)c1ccc2ccccc2c1 CHEMBL516308 EC50 51.0 nM
CCCc1ccc(S(=O)(=O)Nc2ccc3c(c2)ncn3Cc2ccccc2)cc1 CHEMBL517181 EC50 52.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(OC)ccc2F)c1C CHEMBL5278206 IC50 53.0 nM
CCCCOc1cc(NC(=O)c2nnn(-c3cc(OC)ccc3OC)c2C)cc(C(C)(C)C)c1 CHEMBL5266983 IC50 54.0 nM
Cc1c(C)c(C)c(S(=O)(=O)Nc2ccc3c(c2)ncn3-c2ccc3ccccc3c2)c(C)c1C CHEMBL514896 EC50 55.0 nM
CCCCCCn1cnc2cc(NS(=O)(=O)c3ccccc3Cl)ccc21 CHEMBL465058 EC50 55.0 nM
COC(=O)CC1CN(S(=O)(=O)c2ccc(F)cc2)c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2S1 CHEMBL4217890 EC50 55.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(C(F)(F)F)ccc2OC)c1C CHEMBL5270384 IC50 59.0 nM
CCOP(=O)(OCC)C(=Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)P(=O)(OCC)OCC CHEMBL458767 EC50 60.0 nM
C[C@@]1(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)CN(C(=O)NCc2ccccc2)C[C@@H]1c1ccccc1 CHEMBL4785706 EC50 60.0 nM
COc1ccc(Cl)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C#N CHEMBL4877818 IC50 61.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(OC(F)(F)F)ccc2OC)c1C CHEMBL5267038 IC50 70.0 nM
CCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(OC)ccc2OC)c1C CHEMBL5266231 IC50 77.0 nM
CC(C)(C)c1nc(-c2cc(Cl)cc(NS(=O)(=O)c3cc(F)ccc3F)c2F)c(-c2ccnc(N)n2)s1 CHEMBL5202550 EC50 81.4 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3cc(Br)cc(C(C)(C)C)c3)c2C)c1 CHEMBL5277595 IC50 85.0 nM
CC(C)(C)c1nc(-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2F)c(-c2ccnc(N)n2)s1 CHEMBL2028663 EC50 87.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2c(OC)cccc2OC)c1C CHEMBL5287237 IC50 93.0 nM
O=S(=O)(Nc1ccc2c(c1)ncn2Cc1ccccc1)c1ccccc1F CHEMBL516337 EC50 101.0 nM
COc1ccc(Cl)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1N CHEMBL4871664 EC50 110.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3cc(N(C)C)cc(C(C)(C)C)c3)c2C)c1 CHEMBL5287939 IC50 110.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(OC)ccc2C)c1C CHEMBL5286475 IC50 120.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2ccccc2)c1C CHEMBL5267901 IC50 120.0 nM
CNc1cc(NC(=O)c2nnn(-c3cc(OC)ccc3OC)c2C)cc(C(C)(C)C)c1 CHEMBL5273565 IC50 120.0 nM
COc1cc(NC(=O)c2nnn(-c3cc(OC)ccc3OC)c2C)cc(C(C)(C)C)c1 CHEMBL5272707 IC50 120.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3cc(C#N)cc(C(C)(C)C)c3)c2C)c1 CHEMBL5271913 IC50 120.0 nM
O=S(=O)(c1ccccc1)N(CC(F)(F)F)c1ccc(C(O)(CC(F)(F)F)C(F)(F)F)cc1 CHEMBL388024 Log EC50 125.89 nM
CC(C)[C@H]1CCCN1c1cc(-c2ccccc2O)nnc1N CHEMBL5409404 EC50 140.0 nM
CC(C)(O)CNC(=O)C[C@H]1CN(S(=O)(=O)c2ccc(F)cc2)c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2S1 CHEMBL4214210 EC50 144.0 nM
Cc1c(Cl)cccc1Oc1cccn2c(C3CCCCCC3)nnc12 CHEMBL1800116 EC50 150.0 nM
Cc1c(Cl)cccc1Oc1cccn2c(C34CCC(CC3)C4)nnc12 CHEMBL1800117 EC50 150.0 nM
COC1(c2nnc3c(Oc4cccc(Cl)c4C)cccn23)CCCCCC1 CHEMBL1800118 EC50 150.0 nM
COC12CC3CC(C1)CC(c1nnc4c(Oc5cccc(Cl)c5C)cccn14)(C3)C2 CHEMBL1800119 EC50 150.0 nM
Cc1c(Cl)cccc1Oc1cccn2c([C@]34CCC(C[C@H]3O)C4(C)C)nnc12 CHEMBL1800120 EC50 150.0 nM
Cc1c(Cl)cccc1Oc1cccn2c(CC3CC4CCC3C4)nnc12 CHEMBL1800121 EC50 150.0 nM
Cc1c(Cl)cccc1Oc1cccn2c(C34CCC(F)(CC3)CC4)nnc12 CHEMBL1800133 EC50 150.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3cc(C(C)(C)C)ccc3NC(=O)OC(C)(C)C)c2C)c1 CHEMBL5268267 EC50 150.0 nM
CCCCN(CCCC)c1cc(NC(=O)c2nnn(-c3cc(OC)ccc3OC)c2C)cc(C(C)(C)C)c1 CHEMBL5289489 IC50 150.0 nM
C[C@]1(c2ccc(F)cc2)CN(C(=O)C2CCN(S(C)(=O)=O)CC2)C[C@H]1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4763092 EC50 151.0 nM
CCCC(O)(c1ccc(N(CC(F)(F)F)S(=O)(=O)c2ccccc2)cc1)C(F)(F)F CHEMBL242528 Log EC50 158.49 nM
COc1ccc(C)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1N CHEMBL4873947 EC50 160.0 nM
COc1ccc(C)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C#N CHEMBL4856618 EC50 160.0 nM
CC(C)(O)CNC(=O)CC1CN(S(=O)(=O)c2ccc(F)cc2)c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2S1 CHEMBL4214711 EC50 175.0 nM
O=S(=O)(Cc1ccccc1Cl)Nc1ccc2c(c1)ncn2Cc1ccccc1 CHEMBL516149 EC50 176.0 nM
C[C@]1(c2ccc(F)cc2)CN(C(=O)NCc2ccc3c(c2)OCO3)C[C@H]1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4761927 EC50 177.0 nM
COc1ccc(OC)c(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)c2N)c1 CHEMBL4850664 IC50 180.0 nM
CC(C)(O/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(C[n+]3ccccc3)CS[C@H]12)c1csc(N)n1)C(=O)O CHEMBL44354 AC50 180.0 nM
COc1ccc(CNC(=O)N2C[C@@H](c3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)[C@@](C)(c3ccc(F)cc3)C2)cc1 CHEMBL4794795 EC50 189.0 nM
O=S(=O)(c1ccc(F)cc1)N(CC(F)(F)F)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL3094369 EC50 190.0 nM
CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(c(/C=N/N5CCN(C)CC5)c(O)c4c3C2=O)NC(=O)/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C CHEMBL374478 EC50 190.0 nM
NC(=O)CC1CN(S(=O)(=O)c2ccc(F)cc2)c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2S1 CHEMBL4213493 EC50 190.0 nM
CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2ccc(Cl)cn12 CHEMBL54349 AC50 191.8 nM
O=S(=O)(Cc1ccccc1Cl)Nc1ccc2c(ccn2Cc2ccccc2)c1 CHEMBL514421 EC50 197.0 nM
COc1ccc(Cl)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C(C)=O CHEMBL4870712 EC50 200.0 nM
Cc1ccc(NC(=O)C2(c3ccc4c(c3)OC(F)(F)O4)CC2)nc1-c1cccc(C(=O)O)c1 CHEMBL2103870 AC50 200.0 nM
CC[C@H]1CCCN1c1cc(-c2ccccc2O)nnc1N CHEMBL5406315 IC50 200.0 nM
Nc1nnc(-c2ccccc2O)cc1N1CCC[C@@H]1C1CC1 CHEMBL5431862 IC50 200.0 nM
O=S(=O)(c1ccc(F)cc1)C1(c2ccc(C(Oc3ccccc3)(C(F)(F)F)C(F)(F)F)cc2)CCCC1 CHEMBL4798289 EC50 205.0 nM
CC[C@]1(c2ccccc2)CN(C(=O)NCc2ccccc2)C[C@H]1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4763008 EC50 206.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3ccc(O)c(C(C)(C)C)c3)c2C)c1 CHEMBL5266755 IC50 210.0 nM
O=C(Cc1cccc2ccccc12)Nc1ccc2c(c1)ncn2Cc1ccccc1 CHEMBL464687 EC50 217.0 nM
CC(C)(O)CNC(=O)C[C@@H]1CN(S(=O)(=O)c2ccc(F)cc2)c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2S1 CHEMBL4213534 EC50 228.0 nM
O=S(=O)(c1ccc(F)cc1)C1(c2ccc(C(Cl)(C(F)(F)F)C(F)(F)F)cc2)CCCC1 CHEMBL4555738 EC50 229.0 nM
C[C@]1(c2ccc(F)cc2)CN(C(=O)NCc2ccc(C#N)cc2)C[C@H]1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4755633 EC50 231.0 nM
CC(O)(c1ccc(C2(S(=O)(=O)c3ccc(F)cc3)CCCC2)cc1)C(F)(F)F CHEMBL4440933 EC50 239.0 nM
COc1ccc(F)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4868841 EC50 240.0 nM
CCCCN(Cc1cc(Cl)c(O)c(Cl)c1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL493241 EC50 250.0 nM
O=C(CC1CN(S(=O)(=O)c2ccc(F)cc2)c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2S1)Nc1ccncc1 CHEMBL4216643 EC50 250.0 nM
C[C@H](Nc1cc(F)c(S(=O)(=O)Nc2cscn2)c(F)c1)c1ccccc1F CHEMBL4466858 EC50 250.0 nM
COc1ccc(Cl)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4878794 IC50 250.0 nM
COc1cc(OC)c(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C)cc1Cl CHEMBL4860882 EC50 250.0 nM
CCCCOC(C)(C)c1ccc(S(=O)(=O)c2nnn(-c3cc(OC)ccc3OC)c2C)cc1 CHEMBL4853694 IC50 250.0 nM
Cc1cc(CCCOc2c(C)cc(-c3noc(C(F)(F)F)n3)cc2C)on1 CHEMBL29609 pEC50 251.19 nM
O=C(CC1CN(S(=O)(=O)c2ccc(F)cc2)c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2S1)Nc1nncs1 CHEMBL4209091 EC50 254.0 nM
C[C@]1(c2ccccc2)CN(S(C)(=O)=O)C[C@H]1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4748498 EC50 257.0 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(-c3cccc(Cl)c3)c(C(=O)c3ccccc3Cl)s2)cc1 CHEMBL3105681 EC50 260.0 nM
COc1ccc(C)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C(C)=O CHEMBL4872210 IC50 260.0 nM
COc1cc(C(C)=O)c(Cl)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4849299 EC50 260.0 nM
COc1ccc(OC)c(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C#N)c1 CHEMBL4849908 EC50 260.0 nM
COc1cc2[nH]c(C)c(CCN3CCN(c4ccccc4)CC3)c2cc1OC CHEMBL2107011 AC50 260.0 nM
CCC[C@@]1(CCc2ccccc2)CC(O)=C([C@H](CC)c2cccc(NS(=O)(=O)c3ccc(C(F)(F)F)cn3)c2)C(=O)O1 CHEMBL222559 AC50 260.0 nM
CC(C)(O)CNC(=O)CC1Cc2cc(C(O)(C(F)(F)F)C(F)(F)F)ccc2N(S(=O)(=O)c2ccc(F)cc2)C1 CHEMBL4211051 EC50 270.0 nM
O=[N+]([O-])c1ccccc1S(=O)(=O)Nc1ccc2c(c1)ncn2Cc1ccccc1 CHEMBL457277 EC50 271.0 nM
CCOP(=O)(OCC)C(=Cc1ccccc1)P(=O)(OCC)OCC CHEMBL4084567 EC50 271.0 nM
NC(c1ccc(C2(S(=O)(=O)c3ccc(F)cc3)CCCC2)cc1)(C(F)(F)F)C(F)(F)F CHEMBL4580320 EC50 275.0 nM
C[C@]1(c2ccccc2)CN(CC(N)=O)C[C@H]1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4794330 EC50 276.0 nM
COc1cc(OC)c(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C)cc1C CHEMBL4848816 EC50 280.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3cc(C(C)(C)C)ccc3OCCN(C)C)c2C)c1 CHEMBL5269205 IC50 280.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3ccc(N)c(C(C)(C)C)c3)c2C)c1 CHEMBL5273515 EC50 280.0 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)(C)CN(C)CCC(c2ccccc2)c2ccccc2)C1c1cccc([N+](=O)[O-])c1 CHEMBL250270 AC50 285.7 nM
CCOP(=O)(OCC)C(=Cc1c2ccccc2cc2ccccc12)P(=O)(OCC)OCC CHEMBL4095208 EC50 290.0 nM
FC(F)(F)Oc1ccccc1Oc1cccn2c(C3(c4ccc(Cl)cc4)CC3)nnc12 CHEMBL3318967 EC50 300.0 nM
COc1ccc(C(C)(C)C)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4861132 IC50 300.0 nM
COc1ccc([C@H]2CCC(=O)N[C@@H]2C)cc1-c1ccc(C(F)(F)F)cc1[C@@H]1CC[C@H]2[C@@H](c3cc(C(F)(F)F)cc(C(F)(F)F)c3)OC(=O)N12 CHEMBL4857594 EC50 300.0 nM
CNc1ccc(NC(=O)c2nnn(-c3cc(OC)ccc3OC)c2C)cc1C(C)(C)C CHEMBL5279641 EC50 300.0 nM
CC(C)(C(=O)N1CCOCC1)c1ccc2c(-c3ccc(F)cc3)cc(C(N)=O)nc2c1 CHEMBL5421645 EC50 300.0 nM
N#Cc1ccccc1COC(c1ccc(C2(S(=O)(=O)c3ccc(F)cc3)CCCC2)cc1)(C(F)(F)F)C(F)(F)F CHEMBL4795359 EC50 303.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3cc(Oc4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)cc(C(C)(C)C)c3)c2C)c1 CHEMBL5172753 DC50 310.0 nM
C[C@]1(c2ccccc2)CN(Cc2ccccc2)C[C@H]1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4757686 EC50 321.0 nM
C/C(=C\CC/C(C)=C/CC[C@]1(C)CCc2cc(O)cc(C)c2O1)CC/C=C(\C)C(=O)O CHEMBL4463788 Kd 330.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cccc(OC)c2OC)c1C CHEMBL5278057 IC50 330.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3cc(B4OC(C)(C)C(C)(C)O4)cc(C(C)(C)C)c3)c2C)c1 CHEMBL5279796 IC50 330.0 nM
O=[N+]([O-])c1ccc(S(=O)(=O)Nc2ccc3c(c2)ncn3Cc2ccccc2)cc1 CHEMBL457278 EC50 336.0 nM
O=S(=O)(Nc1ccc2ncn(Cc3ccccc3)c2c1)c1ccccc1Cl CHEMBL457297 EC50 340.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3cc(O)cc(C(C)(C)C)c3)c2C)c1 CHEMBL5274653 IC50 340.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3ccc(OC)c(C(C)(C)C)c3)c2C)c1 CHEMBL5287048 IC50 340.0 nM
COc1ccc(Cl)cc1-c1nc(C)c(S(=O)(=O)c2ccc(C(C)(C)C)cc2)n1C CHEMBL4847661 IC50 350.0 nM
COc1cc(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C)c(OC)cc1C#N CHEMBL4879151 IC50 360.0 nM
COc1ccc(Cl)cc1-c1ncc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)[nH]1 CHEMBL4850921 EC50 360.0 nM
Fc1ccc(C(c2ccccc2)(c2ccccc2F)n2ccnc2)cc1 CHEMBL2107430 AC50 360.0 nM
CC(=O)N1C[C@@H](c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)[C@@](C)(c2ccccc2)C1 CHEMBL4739950 EC50 361.0 nM
C=CCOC(c1ccc(C2(S(=O)(=O)c3ccc(F)cc3)CCCC2)cc1)(C(F)(F)F)C(F)(F)F CHEMBL4748976 EC50 371.0 nM
O=S(=O)(Cc1ccccc1Cl)Nc1ccc2ncn(Cc3ccccc3)c2c1 CHEMBL457296 EC50 376.0 nM
O=C(CC1CN(S(=O)(=O)c2ccc(F)cc2)c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2S1)N1CCOCC1 CHEMBL4205428 EC50 380.0 nM
O=S(=O)(Nc1ccc2c(c1)ncn2-c1ccc2ccccc2c1)c1ccccc1Cl CHEMBL457674 EC50 385.0 nM
O=S(=O)(Nc1ccc2c(c1)ncn2Cc1ccccc1)c1ccc(-c2ccccc2)cc1 CHEMBL458775 EC50 388.0 nM
COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)C)C1c1cccc([N+](=O)[O-])c1 CHEMBL1428 EC50 390.0 nM
CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)CC#N)[C@H]2SC1 CHEMBL2110602 AC50 390.0 nM
Clc1ccc(C2(c3nnc4c(Oc5ccccc5N5CCOCC5)cccn34)CC2)cc1 CHEMBL3318966 EC50 400.0 nM
O=c1[nH]c2ccccc2n1CCCN1CCN(C(c2ccccc2)c2ccccc2)CC1 CHEMBL13828 EC50 400.0 nM
CCC(=O)[C@@]1(C)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C CHEMBL1200617 EC50 400.0 nM
CC(=O)Nc1nc(C(C)C)c(-c2cnc(N(C)C(=O)c3c(F)cccc3Cl)c(N3CCCCC3)c2)s1 CHEMBL3598077 EC50 400.0 nM
C[C@H](Nc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1Cl)c1cc(F)ccc1F CHEMBL4580996 EC50 400.0 nM
COc1cc(Cl)c(Cl)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4875869 IC50 400.0 nM
COc1ccc(C)cc1-c1nc(C)c(S(=O)(=O)c2ccc(C(C)(C)C)cc2)n1C CHEMBL4850195 IC50 400.0 nM
COc1cc(C(C)=O)c(C)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4859334 EC50 400.0 nM
COc1ccc(OC)c(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)OC)cc3)c2C)c1 CHEMBL4859314 IC50 400.0 nM
COc1ccc(C(F)(F)F)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4850074 IC50 410.0 nM
C[C@H](Nc1cc(F)c(S(=O)(=O)Nc2nccs2)cc1Cl)c1ccc(F)cc1F CHEMBL4530743 EC50 420.0 nM
COC[C@H](Nc1cc(F)c(S(=O)(=O)Nc2nccs2)cc1Cl)c1ccccc1 CHEMBL4544968 EC50 420.0 nM
COc1cc(C(=O)NS(=O)(=O)c2ccccc2C)ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12 CHEMBL603 AC50 420.6 nM
O=[N+]([O-])c1ccccc1CS(=O)(=O)Nc1ccc2c(c1)ncn2Cc1ccccc1 CHEMBL457272 EC50 428.0 nM
CS(=O)(=O)c1ccc(F)cc1C(=O)N1CCC(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 CHEMBL2180905 EC50 430.0 nM
O=S(=O)(c1ccc(F)cc1)[C@@]1(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)CCNC1 CHEMBL3907312 EC50 434.0 nM
COc1ccc([C@@H](C)O)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4863781 EC50 440.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2ccc(OC)cc2OC)c1C CHEMBL5276676 IC50 440.0 nM
CCCCCCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cc(OC)ccc2OC)c1C CHEMBL5287648 IC50 440.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cccnc2OC)c1C CHEMBL5286721 IC50 440.0 nM
CN(C)S(=O)(=O)NC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(C(=O)N1CCOCC1)=Cc1ccccc1-3 CHEMBL3126845 IC50 440.0 nM
C[C@]1(c2ccccc2)CN(C(=O)NCc2ccccc2)C[C@H]1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4752132 EC50 441.0 nM
CC(C)N(CCCCOCC(=O)NS(C)(=O)=O)c1cnc(-c2ccccc2)c(-c2ccccc2)n1 CHEMBL238804 AC50 450.0 nM
O=S(=O)(c1ccc(F)cc1)C1(c2ccc(C(OCc3c(F)cccc3F)(C(F)(F)F)C(F)(F)F)cc2)CCCC1 CHEMBL4787430 EC50 463.0 nM
O=S(=O)(c1ccc(F)cc1)C1(c2ccc(C(OCc3ccccc3Cl)(C(F)(F)F)C(F)(F)F)cc2)CCCC1 CHEMBL4756437 EC50 469.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3ccc(N(C)C)c(C(C)(C)C)c3)c2C)c1 CHEMBL5276756 IC50 470.0 nM
C[C@@]1(c2ccc(F)cc2)CN(C(=O)NCc2ccccc2)C[C@@H]1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4741480 EC50 472.0 nM
C[C@]1(c2ccc(F)cc2)CN(C(=O)NCc2ccccc2)C[C@H]1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4755131 EC50 474.0 nM
CC(=O)N1CCC(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)(S(=O)(=O)c2ccc(F)cc2)C1 CHEMBL3976875 EC50 480.0 nM
COc1ccc(Cl)cc1-n1cc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)nn1 CHEMBL4850323 IC50 480.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3cccc(C(C)(C)C)c3)c2C)c1 CHEMBL5273045 IC50 480.0 nM
CCCOCCN(C(=O)CCl)c1c(CC)cccc1CC CHEMBL1867271 EC50 490.0 nM
C[C@]1(c2ccc(F)cc2)CN(C(=O)C2CCN(C(=O)CC#N)CC2)C[C@H]1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4756133 EC50 495.0 nM
Clc1ccc(C2(c3nnc4c(Oc5ccccc5-c5ccccc5)cccn34)CC2)cc1 CHEMBL3318970 EC50 500.0 nM
[2H]C([2H])([2H])N(C(=O)c1c(Cl)cccc1Cl)c1ccc(-c2cc(NC(C)=O)nn2C(C)C)cc1N1CC2CC2C1 CHEMBL3598052 EC50 500.0 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(C)=O)nn2C2CCCC2)cc1N1CC2CC2C1 CHEMBL3598070 EC50 500.0 nM
COc1cc(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C)c(OC)cc1C CHEMBL4876988 IC50 500.0 nM
COc1ccc(C)cc1-n1cc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)nn1 CHEMBL4858627 IC50 500.0 nM
COc1cc(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C)c(OC)cc1C(C)=O CHEMBL4855988 EC50 500.0 nM
COc1ccc(Cl)cc1-c1nc(C)c(S(=O)(=O)c2ccc(C(C)(C)C)cc2)[nH]1 CHEMBL4865234 EC50 500.0 nM
CCc1c(S(=O)(=O)c2ccc(C(C)(C)C)cc2)nnn1-c1cc(OC)ccc1OC CHEMBL4852446 IC50 500.0 nM
CC(C)[C@@H](NC(=O)CC1CC1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398717 EC50 500.0 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)OC2CCCN(Cc3ccccc3)C2)C1c1cccc([N+](=O)[O-])c1 CHEMBL2074972 AC50 500.0 nM
Clc1ccc(C(Cn2ccnc2)OCc2c(Cl)cccc2Cl)c(Cl)c1 CHEMBL1571863 AC50 500.0 nM
CC(O)(c1ccc(N(CC(F)(F)F)S(=O)(=O)c2ccccc2)cc1)C(F)(F)F CHEMBL242527 Log EC50 501.19 nM
O=C(Cc1ccccc1Cl)Nc1ccc2c(c1)ncn2Cc1ccccc1 CHEMBL464686 EC50 515.0 nM
CC(C)(O)CC(=O)NCC1CN(S(=O)(=O)c2ccc(F)cc2)c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2S1 CHEMBL4218626 EC50 520.0 nM
O=S(=O)(c1ccc(F)cc1)[C@]1(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)CCNC1 CHEMBL4115190 EC50 520.0 nM
COc1ccccc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4871806 IC50 530.0 nM
CCCCOc1ccc(C(C)(C)C)cc1NC(=O)c1nnn(-c2cccc(OC)c2)c1C CHEMBL5290246 IC50 530.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3cc(C(C)(C)C)ccc3OCCN3CCOCC3)c2C)c1 CHEMBL5269952 IC50 540.0 nM
CCC(Nc1nnc(-c2ccc(OC)cc2)o1)[C@H]1CC[C@@H](c2ccnc3c(F)cc(F)cc32)CC1 CHEMBL4746203 EC50 550.0 nM
COc1cc(Br)c(Cl)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4869828 IC50 550.0 nM
COc1ccc(Cl)cc1-c1ncc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)n1C CHEMBL4877373 IC50 550.0 nM
CC(C)(C)NC(=O)Cn1c(C(C)(C)C)cc2cc(C(C)(C)C(=O)NC(C)(C)C)ccc21 CHEMBL1643737 EC50 570.0 nM
N#Cc1ccc(S(=O)(=O)N(CC(F)(F)F)c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)cc1 CHEMBL3094367 EC50 571.0 nM
CCOC(=O)N1C[C@@H](c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)[C@@](C)(c2ccccc2)C1 CHEMBL4788702 EC50 599.0 nM
CC(C)(C)NC(=O)C(c1ccccn1)n1ccc2cc(C(C)(C)C(=O)NC(C)(C)C)ccc21 CHEMBL1643739 EC50 600.0 nM
COc1ccc2c(c1)C1CC1(C(=O)N1CC3CCC(C1)O3)Cn1c-2c(C2CCCCC2)c2ccc(C(=O)NS(=O)(=O)N(C)C)cc21 CHEMBL3126851 EC50 600.0 nM
Clc1ccc(C2(c3nnc4c(OC5CCCCC5)cccn34)CC2)cc1 CHEMBL3318973 EC50 600.0 nM
COc1cc(F)c(C)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4868786 IC50 600.0 nM
COc1cc(C#N)c(Cl)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4872624 IC50 600.0 nM
COc1cc(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C)c(OC)cc1Br CHEMBL4856961 EC50 600.0 nM
COc1cc(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C)c(OC)cc1Cl CHEMBL4869893 EC50 600.0 nM
CC1CC=C(c2cc(C(N)=O)nc3cc(CN4C(=O)CCC4=O)ccc23)CC1 CHEMBL3958138 EC50 600.0 nM
C[C@H]1CCCN1c1cc(-c2ccccc2O)nnc1N CHEMBL5401472 IC50 600.0 nM
C[C@]1(c2ccc(F)cc2)CN(C(=O)NCc2ccncc2)C[C@H]1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4750694 EC50 604.0 nM
Cc1ccc(C2=C(n3cnnn3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL5398266 EC50 608.0 nM
CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(CSc3nc(=O)c(O)nn3C)CS[C@H]12)c1csc(N)n1 CHEMBL161 AC50 620.0 nM
C[Si](C)(O)c1ccc(N(CC(F)(F)F)S(=O)(=O)c2ccccc2)cc1 CHEMBL3781062 EC50 630.0 nM
C[C@H](Nc1cc(F)c(S(=O)(=O)Nc2cscn2)c(F)c1)c1cc(C#N)ccc1F CHEMBL4459170 EC50 630.0 nM
O=S(=O)(c1ccc(F)cc1)C1(c2ccc(C(OCc3ccccc3F)(C(F)(F)F)C(F)(F)F)cc2)CCCC1 CHEMBL4793401 EC50 630.0 nM
CC(=O)N1CCC(C)(C(=O)N2CC[C@](c3ccc(C(OCc4c(F)cccc4F)(C(F)(F)F)C(F)(F)F)cc3)(S(=O)(=O)c3ccc(F)cc3)C2)CC1 CHEMBL3894847 EC50 630.0 nM
O=C(O)[C@H]1CC[C@H](C(=O)N2CC[C@](c3ccc(C(OCc4c(F)cccc4Cl)(C(F)(F)F)C(F)(F)F)cc3)(S(=O)(=O)c3ccc(F)cc3)C2)CC1 CHEMBL3944677 EC50 630.0 nM
O=S(=O)(c1ccccc1)N(CC(F)(F)F)c1ccc(C(O)(C#Cc2ccccc2)C(F)(F)F)cc1 CHEMBL396953 Log IC50 630.96 nM
COc1ccc([C@H](C)O)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4858090 EC50 640.0 nM
C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc(CCCCC)cc1O CHEMBL190461 AC50 670.0 nM
Cc1ccc2c(c1C)N(S(=O)(=O)c1ccc(C(C)(C)C)cc1)Cc1ccc(C(F)(F)F)nc1N2 CHEMBL2164575 EC50 677.0 nM
CCS(=O)(=O)c1ccccc1-c1ccc(-c2nnc(C3(c4ccc(Cl)cc4)CCC3)n2C)c(Cl)c1 CHEMBL496307 EC50 700.0 nM
CS(=O)(=O)c1ccccc1Oc1cccn2c(C3(c4ccc(Cl)cc4)CC3)nnc12 CHEMBL3318969 EC50 700.0 nM
C=C[C@@]1(C)CC(=O)[C@]2(O)[C@@]3(C)[C@@H](O)CCC(C)(C)[C@@H]3[C@H](O)[C@H](OC(C)=O)[C@@]2(C)O1 CHEMBL52606 EC50 700.0 nM
COc1cc(Cl)c(C)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4869913 IC50 700.0 nM
CCc1cc(OC)c(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C)cc1OC CHEMBL4875872 IC50 700.0 nM
COC(=O)c1cc(OC)c(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C)cc1Cl CHEMBL4855078 IC50 700.0 nM
CCc1c(S(=O)(=O)c2ccc(C(C)(C)C)cc2)nnn1-c1cc(Cl)ccc1OC CHEMBL4859899 IC50 700.0 nM
COc1ccc(OC)c(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C(C)=O)c1 CHEMBL4877224 IC50 700.0 nM
COc1cc(C)c(C)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4878253 EC50 700.0 nM
CCc1cc(OC)c(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C)cc1Cl CHEMBL4850530 EC50 700.0 nM
COc1ccc(OC)c(-c2ncc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)[nH]2)c1 CHEMBL4851405 EC50 700.0 nM
COc1ccc(C)cc1-c1ncc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)[nH]1 CHEMBL4873927 EC50 700.0 nM
CCOc1nc2cccc(C(=O)OC(C)OC(=O)OC3CCCCC3)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 CHEMBL1014 AC50 700.0 nM
CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CS[C@H]12)c1csc(N)n1 CHEMBL1201224 AC50 710.0 nM
CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O CHEMBL548 AC50 720.0 nM
CCCCNc1ccc(NC(=O)c2nnn(-c3cc(OC)ccc3OC)c2C)cc1C(C)(C)C CHEMBL5273985 IC50 730.0 nM
COc1ccccc1-c1cc2cc(C(C)(C)C(=O)NC(C)(C)C)ccc2n1CC(=O)NC(C)(C)C CHEMBL1643736 EC50 740.0 nM
C[C@]1(c2ccccc2)CN(C(=O)c2ccccc2)C[C@H]1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4747305 EC50 740.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3ccccc3C(C)(C)C)c2C)c1 CHEMBL5280444 EC50 740.0 nM
CC(c1ccc(C2(S(=O)(=O)c3ccc(F)cc3)CCCC2)cc1)(C(F)(F)F)C(F)(F)F CHEMBL4447203 EC50 752.0 nM
COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OC/C=C/c2ccccc2)C1c1cccc([N+](=O)[O-])c1 CHEMBL452076 AC50 780.0 nM
O=S(=O)(c1ccc(F)cc1)C1(c2ccc(C(OCc3ccccc3)(C(F)(F)F)C(F)(F)F)cc2)CCCC1 CHEMBL4781699 EC50 781.0 nM
O=C(C1CCCC1)N1CCC(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)(S(=O)(=O)c2ccc(F)cc2)C1 CHEMBL3983495 EC50 794.0 nM
Clc1ccc(C2(c3nnc4c(Oc5ccc6ccccc6c5)cccn34)CC2)cc1 CHEMBL3318971 EC50 800.0 nM
Clc1ccc(C2(c3nnc4c(Oc5cccc(Cl)c5)cccn34)CC2)cc1 CHEMBL3318963 EC50 800.0 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(C)=O)nn2C(C)C)cc1N1CCCC1 CHEMBL3598048 EC50 800.0 nM
COc1ccc(C)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4874083 IC50 800.0 nM
COc1ccc(C)cc1-c1nc(C)c(S(=O)(=O)c2ccc(C(C)(C)C)cc2)[nH]1 CHEMBL4866481 IC50 800.0 nM
CCc1c(S(=O)(=O)c2ccc(C(C)(C)C)cc2)nnn1-c1cc(C)ccc1OC CHEMBL4851763 IC50 800.0 nM
CC(C)=CCOc1ccc(/C=C/C(=O)c2ccc(OCC=C(C)C)cc2OCC(=O)O)cc1 CHEMBL1441961 AC50 800.0 nM
COc1ccc(CO)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4847225 EC50 810.0 nM
COC(=O)C1=C(C#N)NC(C)=C(C(=O)OC(C)C)C1c1cccc([N+](=O)[O-])c1 CHEMBL517427 AC50 814.3 nM
O=C(Nc1ccc2c(c1)N(S(=O)(=O)c1ccc(F)cc1)CCC2)c1c(F)cccc1Cl CHEMBL3314003 EC50 820.0 nM
COc1cc(C(C)C)c(C)cc1-n1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C CHEMBL4851190 EC50 830.0 nM
Cc1ccc(C2=C(n3ncnn3)C(=O)N[C@@](c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 CHEMBL5411387 EC50 845.0 nM
Cc1ccc(SC(=O)c2c(C)noc2-c2cc(C)on2)cc1 CHEMBL1445606 IC50 850.0 nM
Cc1cc(-c2onc(C)c2C(=O)Sc2ccccc2)no1 CHEMBL3632931 IC50 850.0 nM
COc1cccc(-c2nc3ccccc3c(=S)[nH]2)c1 CHEMBL3823873 EC50 860.0 nM
Clc1ccc(CCC(Cn2ccnc2)Sc2c(Cl)cccc2Cl)cc1 CHEMBL1295 AC50 860.0 nM
CO[C@H]1C[C@@H]2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@H]([C@H](C)C[C@@H]2CC[C@@H](O)[C@H](OC)C2)CC(=O)[C@H](C)/C=C(\C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)/C=C/C=C/C=C/1C CHEMBL413 EC50 890.0 nM
Clc1ccc(C2(c3nnc4c(C5CCC5)cccn34)CC2)cc1 CHEMBL3318977 EC50 900.0 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(C)=O)nn2C(C)C2CC2)cc1N1CC2CC2C1 CHEMBL3598075 EC50 900.0 nM
COc1cc(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C)c(OC)cc1C(C)C CHEMBL4847628 EC50 900.0 nM
CCc1cc(OC)c(-n2nnc(S(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C)cc1C CHEMBL4859936 EC50 900.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3cc(C(C)(C)C)ccc3N)c2C)c1 CHEMBL5269184 EC50 900.0 nM
CC(C)Oc1cc(-n2nc(C(C)(C)C)oc2=O)c(Cl)cc1Cl CHEMBL1080648 EC50 900.0 nM
NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(CN3C(=O)CCC3=O)cc2n1 CHEMBL3892073 EC50 900.0 nM
COC(c1ccc(C2(S(=O)(=O)c3ccc(F)cc3)CCCC2)cc1)(C(F)(F)F)C(F)(F)F CHEMBL4571076 EC50 920.0 nM
CCOC(=O)c1c(CSc2ccccc2)n(C)c2cc(Br)c(O)c(CN(C)C)c12 CHEMBL1214598 AC50 920.0 nM
CC(C)(C)NC(=O)Cn1c(-c2ccc(F)cc2F)cc2cc(C(C)(C)C(=O)NC(C)(C)C)ccc21 CHEMBL1643732 EC50 940.0 nM
O=C(Nc1ccc2c(c1)N(S(=O)(=O)c1ccc(F)cc1)CCC2)c1ccccc1Cl CHEMBL3617309 EC50 940.0 nM
CCC(Nc1nnc(-c2ccc(OC)cc2)o1)[C@H]1CC[C@@H](c2ccnc3ccc(F)cc32)CC1 CHEMBL4752094 EC50 940.0 nM
CC(C)c1onc(C[S+]([O-])c2c(Cl)cccc2Cl)c1COc1ccc(/C=C/c2cccc(C(=O)O)c2)c(Cl)c1 CHEMBL468714 XC50 960.0 nM
Clc1ccc(C2(c3nnc4c(Oc5ccccc5Cl)cccn34)CC2)cc1 CHEMBL3318962 EC50 970.0 nM
C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@H]1C(=O)CO CHEMBL509924 AC50 980.0 nM
Clc1ccc(-c2nc3sccn3c2/C=N/OCc2ccc(Cl)c(Cl)c2)cc1 CHEMBL458603 EC50 990.0 nM
COc1ccc(C)cc1-c1ncc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)n1C CHEMBL4874930 EC50 990.0 nM
COc1ccc(OC)c(-n2nnc(C(=O)Nc3cc(C(C)(C)C)ccc3NC(C)=O)c2C)c1 CHEMBL5285078 EC50 990.0 nM
C[C@]1(c2ccc(F)cc2)CN(C(=O)C2CCN(C(=O)C(N)=O)CC2)C[C@H]1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 CHEMBL4762292 EC50 995.0 nM