Cn1c(-c2ccc3c(c2)OCO3)cc2onc(-c3ccccc3)c2c1=O CHEMBL399603 EC50 0.8 nM
Cn1c(-c2ccc(COCCO)cc2)cc2onc(-c3ccccc3)c2c1=O CHEMBL399807 EC50 3.5 nM
COCCOCc1ccc(-c2cc3onc(-c4ccccc4)c3c(=O)n2C)cc1 CHEMBL401032 EC50 3.9 nM
COc1ccc(-c2cc3onc(-c4ccccc4)c3c(=O)n2C)cc1 CHEMBL399602 EC50 4.1 nM
CC(C)(C)c1ccc(COc2cccc(C(=O)O)c2)cc1 CHEMBL5405485 EC50 10.0 nM
OCc1cccc(-c2ccc3nc(-c4ccc(Cl)cc4)cn3c2)c1F CHEMBL4473232 EC50 14.0 nM
O=C(O)c1cccc(OCc2ccc(Cl)cc2Cl)c1 CHEMBL5427562 EC50 21.0 nM
O=C(O)c1ccc2nc(-c3ccc(F)cc3)[nH]c2c1 CHEMBL5086921 EC50 24.0 nM
O=C(Nc1cccc(F)n1)c1cn2cc(-c3ccccn3)ccc2n1 CHEMBL4579076 EC50 25.0 nM
CN(C)Cc1ccc(-c2cc3onc(-c4ccccc4)c3c(=O)n2C)cc1 CHEMBL247879 EC50 26.0 nM
CN1CCN(Cc2ccc(-c3cc4onc(-c5ccccc5)c4c(=O)n3C)cc2)CC1 CHEMBL393713 EC50 31.9 nM
OCc1c(F)ccc(-c2ccc3nc(-c4ccc(Cl)cc4)cn3c2)c1F CHEMBL4475176 EC50 38.0 nM
O=C(O)c1ccc(-c2ccc(OCc3ccccc3)cc2)s1 CHEMBL5419377 EC50 40.0 nM
OCc1cccc(-c2ccc3nc(-c4ccc(Cl)cc4)cn3c2)c1 CHEMBL4576867 EC50 45.0 nM
O=C(O)c1ccc(OCc2ccccc2Cl)cc1 CHEMBL5399104 EC50 50.0 nM
COc1ccc(-c2cc3onc(-c4ccccc4)c3c(=O)n2C)c(OC)c1 CHEMBL246654 EC50 59.2 nM
CC(O)c1cccc(-c2ccc3nc(-c4ccc(Cl)cc4)cn3c2)c1 CHEMBL4461137 EC50 75.0 nM
O=c1[nH]c(-c2ccccc2)cc2onc(-c3ccccc3)c12 CHEMBL246652 EC50 77.5 nM
[2H]C([2H])([2H])Oc1cccc(-c2ccc(NC(=O)C3=C(C(=O)O)CCC3)c(F)c2)c1 CHEMBL5405308 EC50 79.0 nM
CNC(=O)c1cccc(-c2ccc3nc(-c4ccc(Cl)cc4)cn3c2)c1 CHEMBL4455501 EC50 87.0 nM
[2H]C([2H])([2H])Oc1cccc(-c2ccc(NC(=O)C3=C(C(=O)O)CCC3)cc2)c1 CHEMBL5395588 EC50 100.0 nM
C#CCOc1cccc(-c2ccc(NC(=O)C3=C(C(=O)O)CCC3)c(F)c2)c1 CHEMBL5417085 EC50 110.0 nM
O=C(O)c1cccc(OCc2ccc(Cl)cc2)c1 CHEMBL5428767 EC50 110.0 nM
CC(C)OCCOCc1ccc(-c2cc3onc(-c4ccccc4)c3c(=O)n2C)cc1 CHEMBL247478 EC50 113.1 nM
O=C(O)C[C@H](O)C[C@H](O)/C=C/c1c(C2CC2)nc2ccccc2c1-c1ccc(F)cc1 CHEMBL1201753 EC50 120.0 nM
Cn1c(-c2ccncc2)cc2onc(-c3ccccc3)c2c1=O CHEMBL393714 EC50 129.9 nM
CC(C)Oc1cccc(-c2ccc(NC(=O)C3=C(C(=O)O)CCC3)c(F)c2)c1 CHEMBL5408707 EC50 130.0 nM
O=C(Nc1ccccc1)c1cn2cc(-c3ccccn3)ccc2n1 CHEMBL4472621 EC50 140.0 nM
[2H]C([2H])([2H])Oc1cccc(-c2cc(F)c(NC(=O)C3=C(C(=O)O)CCC3)c(F)c2)c1 CHEMBL5417026 EC50 200.0 nM
CCCCOc1cccc(-c2ccc(NC(=O)C3=C(C(=O)O)CCC3)c(F)c2)c1 CHEMBL5394449 EC50 210.0 nM
CC(C)(O)c1cccc(-c2ccc3nc(-c4ccc(Cl)cc4)cn3c2)c1 CHEMBL4564985 EC50 218.0 nM
COc1cccc(-c2ccc(NC(=O)C3=C(C(=O)O)CCC3)c(F)c2)c1 CHEMBL197194 EC50 300.0 nM
[2H]C([2H])([2H])Oc1cccc(-c2cc(F)c(NC(=O)C3=C(C(=O)O)CC(F)(F)C3)c(F)c2)c1 CHEMBL5408943 EC50 300.0 nM
OC1(c2cccc(-c3ccc4nc(-c5ccc(Cl)cc5)cn4c3)c2)COC1 CHEMBL4446736 EC50 323.0 nM
[2H]C([2H])([2H])Oc1ccccc1-c1cc(F)c(NC(=O)C2=C(C(=O)O)CCC2)c(F)c1 CHEMBL5398990 EC50 330.0 nM
CC(C)COc1cccc(-c2ccc(NC(=O)C3=C(C(=O)O)CCC3)c(F)c2)c1 CHEMBL5408286 EC50 400.0 nM
[2H]C([2H])([2H])Oc1cccc(-c2cc(F)c(NC(=O)C3=C(C(=O)O)CSC3)c(F)c2)c1 CHEMBL5396308 EC50 430.0 nM
[2H]C([2H])([2H])Oc1cccc(-c2cc(F)c(NC(=O)C3=C(C(=O)NO)CCC3)c(F)c2)c1 CHEMBL5409772 EC50 460.0 nM
CN(C)CCOc1ccc(Cl)cc1NC(=O)c1cc2[nH]ccc2cc1Cl CHEMBL5415710 Kd 500.0 nM
CC(C)(C)c1ccc(COc2ccc(C(=O)O)cc2)cc1 CHEMBL5426462 EC50 500.0 nM
[2H]C([2H])([2H])Oc1cccc(-c2cc(F)c(NC(=O)C3=C(C(N)=O)CCC3)c(F)c2)c1 CHEMBL5426306 EC50 510.0 nM
O=C(O)c1cccc(OCc2cccc(-c3ccccc3)c2)c1 CHEMBL5436421 EC50 520.0 nM
COCCOc1cccc(-c2ccc(NC(=O)C3=C(C(=O)O)CCC3)c(F)c2)c1 CHEMBL5404750 EC50 700.0 nM
O=C(O)c1cccc(OCc2cccc(Cl)c2)c1 CHEMBL5408864 EC50 970.0 nM
CN(C)CCOc1ccc(Cl)cc1NC(=O)c1cc2c(ccn2C)cc1Cl CHEMBL5416432 Kd 1000.0 nM
[2H]C([2H])([2H])Oc1cccc(-c2cc(F)c(NC(=O)C3=C(C(=O)O)COC3)c(F)c2)c1 CHEMBL5402885 EC50 1000.0 nM
O=C(O)c1ccc(OCc2ccc(Cl)cc2Cl)cc1 CHEMBL5407416 EC50 1000.0 nM