C[C@H](Nc1nc(Cl)nc2c1cnn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O)c1ccccc1 CHEMBL4743437 IC50 0.0027 nM
C[C@H](Nc1cc(Cl)nc2c1cnn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O)c1ccccc1F CHEMBL4471306 Ki 0.005 nM
C[C@@H](Nc1cc(Cl)nc2c1cnn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O)c1ccccc1F CHEMBL5402552 Ki 0.005 nM
C[C@H](Nc1cc(Cl)nc2c1cnn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O)c1ccc(F)cc1 CHEMBL4761506 IC50 0.01 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4749428 IC50 0.027 nM
C[C@H](Nc1nc(Cl)nc2c1ccn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O)c1ccccc1F CHEMBL4776758 IC50 0.028 nM
C[C@H](Nc1nc(Cl)nc2c1ccn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O)c1ccc(F)cc1 CHEMBL4746184 IC50 0.031 nM
C[C@H](Nc1nc(Cl)nc2c1cnn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O)c1cccc(F)c1 CHEMBL4740465 IC50 0.031 nM
C[C@H](Nc1nc(Cl)nc2c1ccn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O)c1cccc(F)c1 CHEMBL4797225 IC50 0.032 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccc(N3CCCNC3=O)cc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5423436 Ki 0.038 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2ncc3c(N4CC5(CCc6ccccc65)C4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL5431118 IC50 0.05 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2ncc3c(NCc4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4790144 IC50 0.052 nM
C[C@@H](Nc1nc(Cl)nc2c1cnn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O)c1ccccc1 CHEMBL4745002 IC50 0.058 nM
C[C@H](Nc1nc(Cl)nc2c1cnn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O)c1ccccc1F CHEMBL4784155 IC50 0.07 nM
C[C@H](Nc1nc(Cl)nc2c1cnn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O)c1ccc(F)cc1 CHEMBL4777161 IC50 0.095 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccc(-c3ccc[nH]c3=O)cc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5404625 IC50 0.1 nM
CN(c1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O)C1CCCC1 CHEMBL4753354 IC50 0.12 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@@H](F)[C@@H]1O CHEMBL4763896 IC50 0.15 nM
CN(c1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@@H]1F)C1CCCC1 CHEMBL4758486 IC50 0.15 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4744502 IC50 0.2 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccc(-c3ccccc3C(=O)O)cc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5398484 IC50 0.2 nM
COC[C@](CO)(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O CHEMBL4764985 EC50 0.22 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccc(N3CCCCC3=O)cc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5439071 IC50 0.26 nM
C[C@H](Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O)c1ccccc1 CHEMBL4780231 IC50 0.3 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4788910 IC50 0.3 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccc(-c3ccccc3)cc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5415259 IC50 0.3 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(-c4cccs4)nc(Cl)nc32)[C@@H]1O CHEMBL5398262 IC50 0.3 nM
CN(Cc1ccccc1)c1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL4452072 Ki 0.318 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NC4CCCC4)nc(Cl)nc32)[C@@H](F)[C@@H]1O CHEMBL4748647 IC50 0.4 nM
O=P(O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4791237 IC50 0.4 nM
Cn1c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc/c1=N/OCc1ccc(I)cc1 CHEMBL5081267 Ki 0.436 nM
Cn1c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc/c1=N/OCc1ccc(Br)cc1 CHEMBL5083600 Ki 0.441 nM
Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)[C@](O)(C#CC2CC2)[C@H]1O CHEMBL5403339 IC50 0.5 nM
C[C@@](CO)(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O CHEMBL4752114 IC50 0.51 nM
Cn1c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc/c1=N/OCc1ccc(S(F)(F)(F)(F)F)cc1 CHEMBL5074970 Ki 0.511 nM
CN(c1nc(Cl)nc2c1cnn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O)[C@H]1CCc2ccccc21 CHEMBL4757563 IC50 0.52 nM
COCC(CO)(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O CHEMBL4743237 IC50 0.53 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4745473 IC50 0.55 nM
O=P(O)(O)C(CO)(CO)OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4786598 IC50 0.57 nM
COCc1nc(NC2CCCC2)c2ncn([C@@H]3O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@@H]3F)c2n1 CHEMBL4748576 IC50 0.6 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N4CC(O)C4)nc(Cl)nc32)[C@@H]1O CHEMBL5415675 IC50 0.6 nM
Cn1c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc/c1=N/OCc1ccc(C(=O)NCCN)cc1 CHEMBL5078828 Ki 0.626 nM
Cn1c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc/c1=N/OCc1ccc(Cl)cc1 CHEMBL5080841 Ki 0.673 nM
C[C@@H](Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O)c1ccccc1 CHEMBL4750588 IC50 0.7 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4)nc(Cl)nc32)[C@@H](F)[C@@H]1O CHEMBL4779616 IC50 0.7 nM
CC(C)Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL4746820 IC50 0.7 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N[C@H]4CCOC4)nc(Cl)nc32)[C@@H](F)[C@@H]1O CHEMBL4761534 IC50 0.8 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(NCC4CC4)nc(Cl)nc32)[C@@H]1O CHEMBL5417110 IC50 0.8 nM
COC(=O)c1ccc(CO/N=c2/ccn([C@@H]3O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]3O)c(=O)n2C)cc1 CHEMBL5086866 Ki 0.848 nM
Cc1ccc(CO/N=c2/ccn([C@@H]3O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]3O)c(=O)n2C)cc1 CHEMBL5076916 Ki 0.894 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N4CCCC4)nc(Cl)nc32)[C@@H](F)[C@@H]1O CHEMBL4741516 IC50 0.9 nM
COCC(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O CHEMBL4751244 IC50 0.96 nM
COC[C@@](CO)(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O CHEMBL4788790 IC50 1.0 nM
CC#C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5398515 IC50 1.0 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(NCC)nc(Cl)nc32)[C@@H]1O CHEMBL5435185 IC50 1.0 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(NCc4ccccc4)nc(Cl)nc32)[C@@H]1O CHEMBL5419527 IC50 1.0 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N[C@@H](C)c4ccccc4)nc(Cl)nc32)[C@@H]1O CHEMBL5409033 IC50 1.0 nM
Cn1c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc/c1=N/OCc1ccc(C(F)(F)F)cc1 CHEMBL5084248 Ki 1.08 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N4Cc5ccccc5C4)nc(Cl)nc32)[C@@H](F)[C@@H]1O CHEMBL4755101 IC50 1.1 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N(C)C)nc(Cl)nc32)[C@@H]1O CHEMBL5404795 IC50 1.1 nM
Cn1c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc/c1=N/OCc1ccc(F)cc1 CHEMBL5081442 Ki 1.14 nM
Cn1c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc/c1=N/OCc1cccc(C(F)(F)F)c1 CHEMBL5081604 Ki 1.27 nM
Cc1nc(NCc2ccccc2)c2ncn([C@@H]3O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]3O)c2n1 CHEMBL4796737 IC50 1.3 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(OCc4ccccc4)nc(Cl)nc32)[C@@H](F)[C@@H]1O CHEMBL4793370 IC50 1.3 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NCc4cccc(Cl)c4)nc(Cl)nc32)[C@@H](F)[C@@H]1O CHEMBL4759136 IC50 1.3 nM
CN(c1nc(Cl)nc2c1nnn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O)[C@H]1CCc2ccccc21 CHEMBL4782655 IC50 1.3 nM
CC(CO)(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O CHEMBL4784951 IC50 1.3 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NC4CCCC4)nc(C(O)C4CC4)nc32)[C@@H](F)[C@@H]1O CHEMBL4753731 IC50 1.4 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4)nc(Cc4ccccc4)nc32)[C@@H](F)[C@@H]1O CHEMBL4763785 IC50 1.5 nM
Cn1c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc/c1=N/OCc1cccc(Cl)c1 CHEMBL5079813 Ki 1.58 nM
C[C@@H](Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@@H]1F)c1ccccc1 CHEMBL4748342 IC50 1.6 nM
Cn1c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc/c1=N/OCc1ccccc1Cl CHEMBL5094601 Ki 1.63 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NC4CC4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4776829 IC50 1.7 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(NC(C)C)nc(Cl)nc32)[C@@H]1O CHEMBL5423764 IC50 1.7 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5393743 IC50 1.7 nM
Cn1c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc/c1=N/OCc1ccc(C(N)=O)cc1 CHEMBL5076275 Ki 1.76 nM
Cn1c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc/c1=N/OCc1ccc(C(=O)NCCCCN)cc1 CHEMBL5089752 Ki 1.78 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccsc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5399345 IC50 1.8 nM
C#Cc1nc(NCc2ccccc2)c2ncn([C@@H]3O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@@H]3F)c2n1 CHEMBL4760025 IC50 2.0 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N[C@H](C)c4ccccc4)nc(Cl)nc32)[C@@H]1O CHEMBL5410317 IC50 2.0 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(NCCO)nc(Cl)nc32)[C@@H]1O CHEMBL5404674 IC50 2.0 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(NC(C)C)cc(Cl)nc32)[C@@H]1O CHEMBL5428426 IC50 2.0 nM
C[C@@H](Nc1nc(Cl)nc2c1cnn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@@H]1F)c1ccccc1 CHEMBL4784883 IC50 2.1 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N(C)C)cc(Cl)nc32)[C@@H]1O CHEMBL5416552 IC50 2.1 nM
COc1nc(NCc2ccccc2)c2ncn([C@@H]3O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]3O)c2n1 CHEMBL4791467 IC50 2.2 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL4755577 Ki 2.21 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NCc4ccc(Cl)cc4)nc(Cl)nc32)[C@@H](F)[C@@H]1O CHEMBL4796788 IC50 2.4 nM
O=P(O)(O)C(CO)OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4753449 IC50 2.4 nM
CCOC(=O)CCNC(=O)c1ccc(CO/N=c2/ccn([C@@H]3O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]3O)c(=O)n2C)cc1 CHEMBL5076684 Ki 2.51 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NC4CC4)nc(Cl)nc32)[C@@H](F)[C@@H]1O CHEMBL4783528 IC50 2.6 nM
Cn1c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc/c1=N/OCc1ccc(C(=O)NCCC(=O)O)cc1 CHEMBL5070874 Ki 2.613 nM
O=C(NCCCCCCNC(=O)c1ccc2c(c1)C1(OC2=O)c2ccc(O)cc2Oc2cc(O)ccc21)c1ccc(CNc2ncnc3c2ncn3[C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc1 CHEMBL4795486 Ki 2.98 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NC4CCCC4)nc(C(O)c4ccccc4)nc32)[C@@H](F)[C@@H]1O CHEMBL4744406 IC50 3.3 nM
Nc1nc(I)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL4585872 Ki 3.33 nM
Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@@H]1F CHEMBL4287314 IC50 3.4 nM
CCc1ccc(CO/N=c2/ccn([C@@H]3O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]3O)c(=O)n2C)cc1 CHEMBL5093165 Ki 3.5 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NCc4ccncc4)nc(Cl)nc32)[C@@H](F)[C@@H]1O CHEMBL4747191 IC50 3.6 nM
CC(C)Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@@H]1F CHEMBL4751771 IC50 3.6 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2nnc3c(NCc4ccccc4Cl)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4798368 IC50 3.9 nM
Cc1nc(NCc2ccccc2)c2ncn([C@@H]3O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@@H]3F)c2n1 CHEMBL4748492 IC50 4.0 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccnc(Cl)c2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5396241 IC50 4.0 nM
C[C@H](Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@@H]1F)c1ccccc1 CHEMBL4779193 IC50 4.1 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4Cl)nc(Cl)nc32)[C@@H](F)[C@@H]1O CHEMBL4784405 IC50 4.2 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)cc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4785104 IC50 4.5 nM
O=c1[nH]c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc1F CHEMBL3606064 Ki 4.51 nM
Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL4475460 Ki 4.57 nM
O=C(Nc1ccn([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)n1)c1ccccc1 CHEMBL4483379 Ki 4.58 nM
CNc1nc(NCc2ccccc2)c2ncn([C@@H]3O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]3O)c2n1 CHEMBL4752232 IC50 5.0 nM
CCNc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@@H]1F CHEMBL4755896 IC50 5.0 nM
C#C[C@@]1(O)[C@@H](COC(Cc2nccs2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5422647 IC50 5.0 nM
C[C@H](Nc1nc(Cl)nc2c1cnn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@@H]1F)c1ccccc1 CHEMBL4742951 IC50 5.4 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2ncc3c(NCc4ccccc4)nc(Cl)nc32)[C@@H](F)[C@@H]1O CHEMBL4752494 IC50 5.9 nM
C#C[C@@]1(O)[C@@H](COC(Cc2cccs2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5411838 IC50 6.0 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(NC)nc(Cl)nc32)[C@@H]1O CHEMBL5421027 IC50 6.0 nM
O=c1[nH]/c(=N/OCc2ccc3ccccc3c2)ccn1[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL4443094 Ki 6.29 nM
Cc1nnc(-c2c[nH]c(=O)[nH]c2=O)cc1[C@H]1C[C@@H]1C(C)C CHEMBL4792487 IC50 6.6 nM
C#CCC(OC[C@H]1O[C@@H](n2cnc3c(NC(C)C)cc(Cl)nc32)[C@H](O)[C@@]1(O)C#C)(C(=O)O)C(=O)O CHEMBL5425274 IC50 7.0 nM
Cn1c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc/c1=N\OCc1ccccc1 CHEMBL4443977 Ki 7.96 nM
C#C[C@@]1(O)[C@@H](COC(Cc2ccncc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5433738 IC50 8.0 nM
Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COC(Cc2ccc(N3CCCNC3=O)cc2)(C(=O)O)C(=O)O)[C@@H](O)[C@@H]1F CHEMBL4793057 IC50 9.0 nM
C#C[C@@]1(O)[C@@H](COC(Cc2cscn2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5435579 IC50 9.0 nM
CN(C(=O)c1ccccc1)c1ccc(CC(OC[C@H]2O[C@@H](n3cnc4c(N)nc(Cl)nc43)[C@@H](F)[C@@H]2O)(C(=O)O)C(=O)O)cc1 CHEMBL5403031 IC50 9.0 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4)nc(-c4ccccc4)nc32)[C@@H](F)[C@@H]1O CHEMBL4798306 IC50 10.0 nM
CSCC(C)(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O CHEMBL4788607 IC50 10.0 nM
O=c1[nH]/c(=N/OCc2ccc(C(F)(F)F)cc2)ccn1[C@H]1C[C@H](O)[C@@H](COP(=O)(O)CP(=O)(O)O)O1 CHEMBL4551648 Ki 10.1 nM
C[C@](CO)(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O CHEMBL4796959 IC50 11.7 nM
CCc1nc(NCc2ccccc2)c2ncn([C@@H]3O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]3O)c2n1 CHEMBL4743019 IC50 12.0 nM
CNc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@@H]1F CHEMBL4762685 IC50 12.0 nM
N#Cc1ccc(Cn2nccc2-c2cc(F)c3nnn(-c4ccc5cn[nH]c5c4)c3c2)cc1 CHEMBL4438144 IC50 12.4 nM
O=C(NCCOCCOCCNC(=O)c1ccc2c(c1)C1(OC2=O)c2ccc(O)cc2Oc2cc(O)ccc21)c1ccc(CNc2ncnc3c2ncn3[C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc1 CHEMBL4761798 Ki 12.6 nM
O=P(O)(O)CS(=O)(=O)C[C@H]1O[C@@H](n2ncc3c(NCc4ccccc4Cl)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4760944 IC50 13.0 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2cnc3c(NC4CCCC4)nc(COc4ccccc4)nc32)[C@H](O)[C@@H]1O CHEMBL4787752 IC50 13.0 nM
C#C[C@@]1(O)[C@@H](COC(Cc2cncs2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5398457 IC50 13.0 nM
CC(C)OC1Oc2ccccc2C(=O)/C1=C\Nc1cccc(S(N)(=O)=O)c1 CHEMBL3798753 Ki 14.0 nM
Cn1c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc/c1=N/OCc1ccc(C(=O)O)cc1 CHEMBL5092522 Ki 14.1 nM
O=S1(=O)NC(Nc2cccc3[nH]ncc23)=Nc2c1cc(Cl)c(F)c2O CHEMBL4127683 IC50 15.0 nM
NNc1nc(N)c2ncn([C@@H]3O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]3O)c2n1 CHEMBL4591580 Ki 15.4 nM
O=c1[nH]/c(=N/OCc2ccccc2)c(F)cn1[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL4470616 Ki 15.9 nM
COC1Oc2ccccc2C(=O)/C1=C\Nc1cccc(S(N)(=O)=O)c1 CHEMBL3797302 Ki 18.0 nM
CCCCOC1Oc2ccccc2C(=O)/C1=C\Nc1cccc(S(N)(=O)=O)c1 CHEMBL3798795 Ki 18.0 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4)nc(CCc4ccccc4)nc32)[C@@H](F)[C@@H]1O CHEMBL4761143 IC50 18.0 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4)nc(C(F)(F)F)nc32)[C@@H](F)[C@@H]1O CHEMBL4749606 IC50 18.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1F CHEMBL4799519 IC50 18.0 nM
CC(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O CHEMBL4741942 IC50 18.0 nM
N#Cc1ccc(Cn2nccc2-c2cc(Cl)c3nnn(-c4ccc5cn[nH]c5c4)c3c2)cc1 CHEMBL4467828 IC50 18.9 nM
C#C[C@@]1(O)[C@@H](COC(CC=C)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5415203 IC50 20.0 nM
N#Cc1ccc(Cn2nccc2-c2ccc3nnn(-c4ccc5cn[nH]c5c4)c3c2)cc1 CHEMBL4576728 IC50 21.0 nM
CC(CS(C)(=O)=O)(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O CHEMBL4754460 IC50 23.0 nM
Nc1nc(Cl)c2ncn([C@@H]3O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]3O)c2n1 CHEMBL4456465 Ki 23.6 nM
C#C[C@@]1(O)[C@@H](COC(CC)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5422784 IC50 24.0 nM
COP(=O)(CP(=O)(O)O)OC[C@H]1O[C@@H](n2ncc3c(NCc4ccccc4Cl)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4790529 IC50 24.7 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2cnc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4791637 IC50 26.0 nM
COC1Oc2ccc(Cl)cc2C(=O)/C1=C\Nc1cccc(S(N)(=O)=O)c1 CHEMBL3799691 Ki 27.0 nM
O=P(O)(O)C(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)c1nn[nH]n1 CHEMBL4749770 IC50 28.0 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2ncc3c(NCc4ccccc4Cl)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4785716 IC50 29.0 nM
CC(CCO)(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O CHEMBL4791561 IC50 31.0 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2cnc3c(NC4CCCC4)cc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4783729 IC50 33.0 nM
Nc1nc(N)c2ncn([C@@H]3O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]3O)c2n1 CHEMBL4462911 Ki 35.7 nM
COC1Oc2c(Cl)cc(Cl)cc2C(=O)/C1=C\Nc1ccccc1S(N)(=O)=O CHEMBL3800324 Ki 42.0 nM
Clc1ccc(Cn2nccc2-c2ccc3nnn(-c4ccc5cn[nH]c5c4)c3c2)c(Cl)c1 CHEMBL4549571 IC50 45.0 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2cnc3c(N4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4782129 IC50 45.0 nM
COC1Oc2c(Cl)cc(Cl)cc2C(=O)/C1=C\Nc1cccc(S(N)(=O)=O)c1 CHEMBL3800429 Ki 46.0 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4Cl)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4788847 IC50 46.0 nM
CN(Cc1ccccc1Cl)c1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COCP(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL4781225 IC50 46.0 nM
Clc1ccc(Cn2nccc2-c2cc(Cl)c3nnn(-c4ccc5cn[nH]c5c4)c3c2)nc1 CHEMBL4454039 IC50 46.1 nM
Nc1nc(SCCC2CCCCC2)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL4536899 Ki 46.9 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4)nc(N4CCCC4)nc32)[C@H](O)[C@@H]1O CHEMBL4763292 IC50 48.0 nM
N#Cc1ccc(Cn2nccc2-c2cc3c(cn2)nnn3-c2ccc3[nH]c(=O)[nH]c3c2)c(Cl)c1 CHEMBL4454426 IC50 49.5 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL583969 IC50 50.0 nM
Cc1nnc(-c2c[nH]c(=O)[nH]c2=O)cc1[C@H]1C[C@@H]1C(F)F CHEMBL4798999 EC50 51.0 nM
C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5404019 IC50 51.0 nM
CC(C)OC1Oc2ccccc2C(=O)/C1=C\Nc1ccc(S(N)(=O)=O)cc1 CHEMBL3798555 Ki 53.0 nM
N#Cc1ccc(Cn2nccc2-c2cc(F)c3nnn(-c4ccc5[nH]c(=O)[nH]c5c4)c3c2)cc1 CHEMBL4516795 IC50 53.5 nM
Fc1cc(Cl)ccc1Cn1nccc1-c1ccc2nnn(-c3ccc4cn[nH]c4c3)c2c1 CHEMBL4463759 IC50 54.0 nM
O=c1[nH]c2ccc(-n3nnc4c(Cl)cc(-c5ccnn5Cc5ccc(Cl)cn5)cc43)cc2[nH]1 CHEMBL4522718 IC50 54.7 nM
N#Cc1ccc(Cn2nccc2-c2cc(Cl)c3nnn(-c4ccc5[nH]c(=O)[nH]c5c4)c3c2)nc1 CHEMBL4456158 IC50 56.0 nM
Nc1nn(-c2ccc3cn[nH]c3c2)c2cc(-c3ccnn3Cc3ccc(Cl)cc3Cl)cnc12 CHEMBL4527606 IC50 56.5 nM
N#Cc1ccc(Cn2nccc2-c2ccc3nnn(-c4ccc5cn[nH]c5c4)c3c2)nc1 CHEMBL4581829 IC50 57.0 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4780085 IC50 58.0 nM
C#C[C@@]1(O)[C@@H](COC(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5420098 IC50 58.0 nM
Cn1c(=O)n([C@H]2[C@H](O)[C@H](O)[C@]3(COP(=O)(O)CP(=O)(O)O)C[C@H]23)cc/c1=N/OCc1ccc(Cl)cc1 CHEMBL5077925 Ki 59.2 nM
C=CCSc1nc(N)c2ncn([C@@H]3O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]3O)c2n1 CHEMBL4472826 Ki 61.9 nM
CCCCOC1Oc2ccccc2C(=O)/C1=C\Nc1ccc(S(N)(=O)=O)cc1 CHEMBL3800455 Ki 63.0 nM
O=S1(=O)N=C(Nc2cc(F)c3[nH]ccc3c2)Nc2c(O)cc(Cl)c(Br)c21 CHEMBL4127838 pIC50 63.1 nM
O=c1[nH]c2ccc(-n3nnc4cnc(-c5ccnn5Cc5ccc(Cl)cc5Cl)cc43)cc2[nH]1 CHEMBL4527142 IC50 63.1 nM
COC1Oc2ccc(Cl)cc2C(=O)/C1=C\Nc1ccccc1S(N)(=O)=O CHEMBL3799027 Ki 64.0 nM
Clc1ccc(Cn2nccc2-c2ccc3nnn(-c4ccc5cn[nH]c5c4)c3c2)cc1 CHEMBL4528781 IC50 65.0 nM
C[C@H](Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COCP(=O)(O)O)[C@@H](O)[C@H]1O)c1ccccc1 CHEMBL4794758 IC50 65.0 nM
Cn1c(=O)n([C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)cc/c1=N/C(=O)NCc1ccccc1 CHEMBL5083016 Ki 71.5 nM
Cc1ccc(Cn2nccc2-c2ccc3nnn(-c4ccc5cn[nH]c5c4)c3c2)cc1 CHEMBL4453205 IC50 78.0 nM
COC1Oc2ccc(Cl)cc2C(=O)/C1=C\Nc1ccc(S(N)(=O)=O)cc1 CHEMBL3797640 Ki 79.0 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2cnc3c(NC4CCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4787380 IC50 83.0 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2cnc3c(N[C@@H]4CCOC4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4786312 IC50 84.0 nM
O=P(O)(O)CCOC[C@H]1O[C@@H](n2ncc3c(NCc4ccccc4Cl)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4743063 IC50 88.0 nM
COC1Oc2ccccc2C(=O)/C1=C\Nc1ccccc1S(N)(=O)=O CHEMBL3799469 Ki 91.0 nM
CN(CC(C)(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O)S(C)(=O)=O CHEMBL4756805 IC50 97.0 nM
O=S1(=O)NC(Nc2cccc(O)c2)=Nc2c(O)cc(F)cc21 CHEMBL4126449 pIC50 100.0 nM
Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)[C@@H](O)[C@H]1O CHEMBL5402847 IC50 100.0 nM
C=C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5397241 IC50 103.0 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2cnc3c(NCCc4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4782440 IC50 105.0 nM
O=C(O)C(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O CHEMBL4781819 IC50 108.0 nM
O=C(O)C(OC[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O CHEMBL4776869 IC50 110.0 nM
COCc1nc(NC2CCCC2)c2ncn([C@@H]3O[C@H](COCP(=O)(O)O)[C@@H](O)[C@H]3O)c2n1 CHEMBL4797235 IC50 118.0 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2cnc3c(NCCc4ccccc4F)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4786456 IC50 121.0 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2cnc3c(NCC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4780463 IC50 124.0 nM
COP(=O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2ncc3c(NCc4ccccc4Cl)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4785684 IC50 130.7 nM
COC1Oc2c(Cl)cc(Cl)cc2C(=O)/C1=C\Nc1ccc(S(N)(=O)=O)cc1 CHEMBL3798620 Ki 138.0 nM
Clc1cc(-c2ccnn2Cc2ccccc2)cc2c1nnn2-c1ccc2cn[nH]c2c1 CHEMBL4450557 IC50 141.0 nM
Clc1ccccc1Cn1nccc1-c1ccc2nnn(-c3ccc4cn[nH]c4c3)c2c1 CHEMBL4443574 IC50 142.0 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2cnc3c(N4CCOCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4798490 IC50 148.0 nM
CN1C(=O)C2(C(C#N)=C(N)Nc3n[nH]cc32)c2cc(OC(F)(F)F)ccc21 CHEMBL4746318 IC50 150.0 nM
C[C@@H](Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COCP(=O)(O)O)[C@@H](O)[C@H]1O)c1ccccc1 CHEMBL4795154 IC50 156.0 nM
Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)[C@@H](O)[C@@H]1F CHEMBL5409473 IC50 159.0 nM
Cc1ccc(-n2cc(C#N)c3cc4c(=O)oc5ccc(C)cc5c4nc32)cc1 CHEMBL5405024 IC50 160.0 nM
Clc1ccc(Cn2nccc2-c2ccc3nnn(-c4ccc5cn[nH]c5c4)c3c2)nc1 CHEMBL4469265 IC50 162.0 nM
O=P(O)(O)CSC[C@H]1O[C@@H](n2ncc3c(NCc4ccccc4Cl)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4782125 IC50 164.0 nM
COc1ccccc1CCNc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COCP(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL4793270 IC50 173.0 nM
Cc1[nH]nc2c1C1(C(=O)N(C)c3ccc(OC(F)(F)F)cc31)C(C#N)=C(N)N2 CHEMBL4788305 IC50 180.0 nM
COc1cc(/C=N/N2C(=O)CNC2=S)cc(OC)c1OC CHEMBL5396784 IC50 180.0 nM
Nc1nc(N2CCNCC2)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL4569080 Ki 184.0 nM
CCCCNc1nc2c(NC)ncnc2n1[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)C(Br)(Br)P(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL5421717 Ki 185.0 nM
C/C(=N\NC(=O)c1ccncc1)N1N=C(c2ccc(F)cc2)CC1c1ccccc1 CHEMBL5270125 IC50 190.0 nM
CC(C)Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COCP(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL4799125 IC50 192.0 nM
CS(=O)(=O)C(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O CHEMBL4789486 IC50 193.0 nM
CC[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(=O)O)C(=O)O)O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]1O CHEMBL5406480 IC50 200.0 nM
Cn1cc(CNc2nc(Cl)nc3c2ncn3[C@@H]2O[C@H](COCP(=O)(O)O)[C@@H](O)[C@H]2O)cn1 CHEMBL4782237 IC50 201.0 nM
O=P(O)(O)CP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(NC4CCCC4)nc(C(O)C4CCOCC4)nc32)[C@@H](F)[C@@H]1O CHEMBL4777118 IC50 202.0 nM
Fc1cc(-c2ccnn2Cc2ccccc2)cc2c1nnn2-c1ccc2cn[nH]c2c1 CHEMBL4473774 IC50 210.0 nM
Cc1cccc(-n2nccc2-c2cc(Cl)c3nnn(-c4ccc5cn[nH]c5c4)c3c2)c1 CHEMBL4592018 IC50 220.0 nM
Cc1ccccc1Cn1nccc1-c1ccc2nnn(-c3ccc4cn[nH]c4c3)c2c1 CHEMBL4547622 IC50 224.0 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2cnc3c(NC4CCCC4)nc(-c4ccccc4)nc32)[C@H](O)[C@@H]1O CHEMBL4786245 IC50 245.0 nM
CN(C[C@H]1O[C@@H](n2ncc3c(NCc4ccccc4Cl)nc(Cl)nc32)[C@H](O)[C@@H]1O)C(=O)CP(=O)(O)O CHEMBL4749007 IC50 248.0 nM
Cc1cccc(C(=O)Nc2ccncc2)c1 CHEMBL5428233 IC50 250.0 nM
Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1 CHEMBL1164951 Ki 255.0 nM
Cc1[nH]nc2c1C1(C(=O)N(C)c3ccc(F)cc31)C(C#N)=C(N)N2 CHEMBL4761451 IC50 260.0 nM
c1ccc(Cn2nccc2-c2ccc3nnn(-c4ccc5cn[nH]c5c4)c3c2)nc1 CHEMBL4591024 IC50 269.0 nM
O=c1oc2ccccc2cc1-c1csc(/N=C/c2ccc(Cl)cc2)n1 CHEMBL5430511 IC50 280.0 nM
COc1cccc(COc2ccc(/C=N/N3C(=O)CNC3=S)cc2)c1 CHEMBL5410463 IC50 280.0 nM
O=C(Nc1ccncc1)c1ccc(Cl)cc1 CHEMBL1438157 IC50 290.0 nM
C/C(=N\NS(=O)(=O)c1ccccc1)c1cc2ccccc2oc1=O CHEMBL5411508 IC50 290.0 nM
Cc1cccc(-n2nccc2-c2ccc3nnn(-c4ccc5cn[nH]c5c4)c3c2)c1 CHEMBL4450136 IC50 306.0 nM
Cc1ccc(-n2nc(C)c3cc(Cl)c(-c4cc(C)ccc4O)nc32)cc1 CHEMBL4746633 IC50 320.0 nM
CC(=O)c1sc(N/N=C/c2cccnc2)nc1C CHEMBL5398467 IC50 320.0 nM
CC(=O)c1sc(N/N=C/c2ccc(N(C)C)cc2)nc1C CHEMBL5406398 IC50 320.0 nM
CC(=O)c1sc(N/N=C/c2ccc[nH]2)nc1C CHEMBL5420104 IC50 320.0 nM
CC(=O)c1sc(N/N=C/c2cc3ccccc3[nH]2)nc1C CHEMBL5417269 IC50 320.0 nM
O=P(O)(O)CS(=O)(=O)NC[C@H]1O[C@@H](n2ncc3c(NCc4ccccc4Cl)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4784125 IC50 328.0 nM
FC(F)(F)c1cccc(-n2nccc2-c2ccc3nnn(-c4ccc5cn[nH]c5c4)c3c2)c1 CHEMBL4458017 IC50 331.0 nM
Cc1cccc(-n2nccc2-c2cc(F)c3nnn(-c4ccc5cn[nH]c5c4)c3c2)c1 CHEMBL4475618 IC50 333.0 nM
COC1Oc2ccccc2C(=O)/C1=C\Nc1ccc(S(N)(=O)=O)cc1 CHEMBL3799629 Ki 338.0 nM
Clc1cccc(-n2nccc2-c2ccc3nnn(-c4ccc5cn[nH]c5c4)c3c2)c1 CHEMBL4588425 IC50 360.0 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2cnc3c(NCc4ccccn4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4791939 IC50 382.0 nM
O=P(O)(O)C(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)C(F)(F)F CHEMBL4744820 IC50 387.0 nM
FC(F)(F)Oc1cccc(-n2nccc2-c2ccc3nnn(-c4ccc5cn[nH]c5c4)c3c2)c1 CHEMBL4580953 IC50 408.0 nM
CCN(CC)c1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)C(Br)(Br)P(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL1206141 Ki 451.0 nM
CN1C(=O)C2(C(C#N)=C(N)Nc3n[nH]cc32)c2cc(F)ccc21 CHEMBL4760778 IC50 460.0 nM
COc1ccc(C(=O)NNC(=O)CSc2nnc(-c3ccc(NS(=O)(=O)c4ccc(C)cc4)cc3)n2-c2ccc(OC)cc2)cc1 CHEMBL5409919 Ki 460.0 nM
O=S(=O)(NC1CCCCCC1)c1ccc(S(=O)(=O)N2CCC(c3nc(O)c4nnn(Cc5cccc(Cl)c5)c4n3)CC2)cc1 CHEMBL5438974 Ki 460.0 nM
Clc1ccc(Cl)c(Cn2nccc2-c2ccc3nnn(-c4ccc5cn[nH]c5c4)c3c2)n1 CHEMBL4465633 IC50 480.0 nM
O=C(CP(=O)(O)O)OC[C@H]1O[C@@H](n2ncc3c(NCc4ccccc4Cl)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4797508 IC50 510.0 nM
c1ccc(-c2ccc(-c3nc(-c4c[nH]c5ccccc45)[nH]c3-c3ccc(-c4ccccc4)cc3)cc2)cc1 CHEMBL5438317 Ki 530.0 nM
COc1ccc(-c2cc(-c3ccc(OC)cc3)c(C#N)c(SCC(=O)Nc3sc4c(c3C#N)CCCC4)n2)cc1 CHEMBL5403331 Ki 530.0 nM
O=C(OC1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1)c1ccc([N+](=O)[O-])cc1 CHEMBL5406328 Ki 530.0 nM
CCOC(=O)c1ccc(NC(=O)CSc2nc(-c3ccc(C)cc3)cc(-c3ccc(OC)cc3)c2C#N)cc1 CHEMBL5405002 Ki 530.0 nM
CCOc1ccc(-c2cc(C(=O)NCCc3ccccc3)c3c(-c4ccc(C)cc4)[nH]nc3n2)cc1 CHEMBL1436168 Ki 530.0 nM
CC1CCC(NC(=O)C2CCCN(S(=O)(=O)c3ccc4[nH]c(-c5ccccc5)nc4c3)C2)CC1 CHEMBL5432792 Ki 530.0 nM
Nc1ccc(-c2nc3cc(Cc4ccc5[nH]c(-c6ccc(N)cc6)nc5c4)ccc3[nH]2)cc1 CHEMBL548209 Ki 530.0 nM
Cc1ccc(C(=O)N2CCc3cc(-c4nc(NC(=O)CN5CCc6ccccc6C5)sc4C)ccc32)cc1 CHEMBL5421860 Ki 530.0 nM
N#CC(OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O CHEMBL4759919 IC50 559.0 nM
O=P(O)(O)COC[C@H]1O[C@@H](n2cnc3c(NC4CC4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL4792721 IC50 588.0 nM
CC(C)c1ccc(Cn2nccc2-c2ccc3nnn(-c4ccc5cn[nH]c5c4)c3c2)cc1 CHEMBL4471082 IC50 594.0 nM
COc1cccc(-n2nccc2-c2ccc3nnn(-c4ccc5cn[nH]c5c4)c3c2)c1 CHEMBL4545510 IC50 646.0 nM
c1cc(Cn2nccc2-c2ccc3nnn(-c4ccc5cn[nH]c5c4)c3c2)ccn1 CHEMBL4444065 IC50 651.0 nM
CN1C(=O)C2(C(C#N)=C(N)Nc3n[nH]cc32)c2ccccc21 CHEMBL4797703 IC50 690.0 nM
CCCCSc1nc2c(N)ncnc2n1[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)C(Br)(Br)P(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL5437993 Ki 831.0 nM
O=P([O-])([O-])CP(=O)([O-])C[C@@H](O)[C@H]1O[C@@H](n2cc(-c3ccc4ccccc4c3)nn2)[C@H](O)[C@@H]1O CHEMBL5403535 IC50 860.0 nM
Cc1ccc(NC2=Nc3c(O)cc(Cl)cc3S(=O)(=O)N2)cc1 CHEMBL4126132 pIC50 1000.0 nM
O=C(O)C(OC[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O)C(=O)O CHEMBL4797871 IC50 1000.0 nM