NC1(C(=O)O)CN(c2nc3ccccc3n([C@H]3C[C@H]4CCC[C@@H](C3)N4[C@@H]3C[C@@H]4CCCC[C@@H](C4)C3)c2=O)C1 CHEMBL3961680 Ki 0.22 nM
CN(C)C1(c2ccccc2)CCC2(CC1)NCCc1c2[nH]c2ccccc12 CHEMBL3894898 Ki 0.26 nM
CN(C)C1(c2ccccc2)CCC2(CC1)OCCc1c2[nH]c2ccccc12 CHEMBL3959398 Ki 0.3 nM
CN(C)C1(C(=O)O)CN(c2nc3ccccc3n([C@H]3C[C@H]4CCC[C@@H](C3)N4[C@@H]3C[C@@H]4CCCC[C@@H](C4)C3)c2=O)C1 CHEMBL3969279 Ki 0.34 nM
CC1Cc2c([nH]c3ccccc23)C2(CCC(c3ccccc3)(N(C)C)CC2)N1 CHEMBL3894557 Ki 0.5 nM
C[C@@H]1C[C@@H]2C[C@H](C1)C[C@@H](N1[C@@H]3CCC[C@H]1C[C@@H](n1c(=O)c(C(=O)O)nc4ccccc41)C3)C2 CHEMBL3647962 EC50 0.55 nM
O=C1CC[C@@H](Cc2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)N1 CHEMBL3704630 Ki 0.8 nM
CC12C[C@H]3C[C@@H](N4[C@@H]5CCC[C@H]4C[C@@H](n4c(=O)c(N6CC[C@@H]6C(=O)O)nc6ccccc64)C5)C[C@@H]1C[C@@H]2C3 CHEMBL4115318 Ki 0.89 nM
COC(=O)C1Cc2c([nH]c3ccccc23)C2(CCC(c3ccccc3)(N(C)C)CC2)N1 CHEMBL3892859 Ki 0.9 nM
COc1cnc(-c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)cn1 CHEMBL3704619 Ki 0.92 nM
C[C@@H]1C[C@@H]2C[C@H](C1)C[C@@H](N1[C@@H]3CCC[C@H]1C[C@@H](n1c(=O)c(N4CC(CC(=O)O)C4)nc4ccccc41)C3)C2 CHEMBL3903565 Ki 1.03 nM
CC(=O)N1CCc2c([nH]c3cc(F)ccc23)C12CCC(c1ccccc1)(N(C)C)CC2 CHEMBL3890825 Ki 1.1 nM
CN(C)C1(Cc2ccccc2)CCC2(CC1)NCCc1c2[nH]c2ccccc12 CHEMBL3966641 Ki 1.1 nM
c1ccc2c(c1)nc(-c1cnccn1)n2[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704618 Ki 1.15 nM
CC1Cc2c([nH]c3ccccc23)C2(CCC(c3ccccc3)(N(C)C)CC2)O1 CHEMBL3909041 Ki 1.2 nM
CN(C)C1(c2cccc(F)c2)CCC2(CC1)OCCc1c2[nH]c2ccccc12 CHEMBL3961861 Ki 1.2 nM
O=C(O)CC1CN(c2nc3ccccc3n([C@H]3C[C@H]4CCC[C@@H](C3)N4[C@@H]3C[C@@H]4CCCC[C@@H](C4)C3)c2=O)C1 CHEMBL3913056 Ki 1.32 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3C2CCCCCCCC2)c1=O CHEMBL3698900 Ki 1.4 nM
CC1(C)[C@H]2CC[C@@H](CCN3[C@@H]4CC[C@H]3C[C@@H](n3c(=O)c(C(=O)O)nc5ccccc53)C4)[C@@H]1C2 CHEMBL3698827 Ki 1.4 nM
CNC1(c2ccccc2)CCC2(CC1)OCCc1c2[nH]c2ccccc12 CHEMBL3953613 Ki 1.4 nM
CN(C)C1(c2ccccc2)CCC2(CC1)NCCc1c2[nH]c2ccc(F)cc12 CHEMBL3954763 Ki 1.4 nM
O=C(O)[C@@H]1CCN1c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)c1=O CHEMBL3935191 Ki 1.46 nM
N[C@@H]1CCN(c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)C1 CHEMBL3695221 Ki 1.6 nM
CN(C)C1(c2ccccc2)CCC2(CC1)OCCc1c2[nH]c2ccc(O)cc12 CHEMBL3959597 Ki 1.6 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3C2CCCCCCCCC2)c1=O CHEMBL3698899 Ki 1.8 nM
c1ccc2c(c1)nc(C1CCCN1)n2[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704582 Ki 1.9 nM
CN(C)[C@@H]1CN(c2nc3ccccc3n([C@H]3C[C@H]4CCC[C@@H](C3)N4[C@@H]3C[C@@H]4CCCC[C@@H](C4)C3)c2=O)[C@@H]1C(=O)O CHEMBL4110144 Ki 1.97 nM
N[C@@H]1CN(c2nc3ccccc3n([C@H]3C[C@H]4CCC[C@@H](C3)N4[C@@H]3C[C@@H]4CCCC[C@@H](C4)C3)c2=O)[C@@H]1C(=O)O CHEMBL4107295 Ki 1.98 nM
CN[C@@H]1CN(c2nc3ccccc3n([C@H]3C[C@H]4CCC[C@@H](C3)N4[C@@H]3C[C@@H]4CCCC[C@@H](C4)C3)c2=O)[C@@H]1C(=O)O CHEMBL4110576 Ki 1.98 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCCC2)c1=O CHEMBL3698904 Ki 2.0 nM
c1ccc2c(c1)nc(-c1nnc[nH]1)n2[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704617 Ki 2.0 nM
c1ccc2c(c1)nc(C[C@@H]1COCCN1)n2[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704632 Ki 2.05 nM
C[C@@H]1C[C@@H]2C[C@H](C1)C[C@@H](N1[C@@H]3CCC[C@H]1C[C@@H](n1c(=O)c(N4CC(C(=O)O)C4)nc4ccccc41)C3)C2 CHEMBL3986914 Ki 2.21 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3C2CC3CCCC(C3)C2)c1=O CHEMBL3647958 Ki 2.4 nM
CC(=O)N1CCc2c([nH]c3ccccc23)C12CCC(c1ccccc1)(N(C)C)CC2 CHEMBL3919062 Ki 2.4 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCCCC2)c1=O CHEMBL3698902 Ki 2.5 nM
O=C(O)CC1CN(c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4[C@@H]3C[C@@H]4CCCC[C@@H](C4)C3)c2=O)C1 CHEMBL3973642 Ki 2.64 nM
OCc1nc2ccccc2n1C1C[C@H]2CCC[C@@H](C1)N2[C@H]1C[C@@H]2CCC[C@@H](C2)C1 CHEMBL3704613 Ki 2.68 nM
O=C(NO)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3695242 Ki 2.7 nM
CC(C)(C)CC(C)(C)N1[C@@H]2CC[C@H]1C[C@@H](n1c(=O)c(C(=O)O)nc3ccccc31)C2 CHEMBL3698898 Ki 2.8 nM
CN(C)C1(c2ccccc2)CCC2(CC1)OCCc1c2[nH]c2ccc(F)cc12 CHEMBL3962932 Ki 2.9 nM
O=C(O)[C@H]1CCN1c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)c1=O CHEMBL4107594 Ki 3.07 nM
COc1ccc(NC(=O)c2nc3ccccc3n([C@@]3(C)C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)cn1 CHEMBL3695235 Ki 3.1 nM
CC(=O)N[C@@H]1CN(c2nc3ccccc3n([C@H]3C[C@H]4CCC[C@@H](C3)N4[C@@H]3C[C@@H]4CCCC[C@@H](C4)C3)c2=O)[C@@H]1C(=O)O CHEMBL4110922 Ki 3.14 nM
CN(C)C1(c2ccc(F)cc2)CCC2(CC1)OCCc1c2[nH]c2ccccc12 CHEMBL3909755 Ki 3.2 nM
CO[C@H]1CN(c2nc3ccccc3n([C@H]3C[C@H]4CCC[C@@H](C3)N4[C@@H]3C[C@@H]4CCCC[C@@H](C4)C3)c2=O)[C@@H]1C(=O)O CHEMBL3960466 Ki 3.56 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3C2/C=C\CCCCC2)c1=O CHEMBL3698814 Ki 3.6 nM
CN(C)C1(c2ccccc2)CCC2(CC1)SCCc1c2[nH]c2ccccc12 CHEMBL3980449 Ki 3.7 nM
O=C(O)[C@@H]1CCN1c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)c1=O CHEMBL3941054 Ki 3.78 nM
Cc1nnc(Cc2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)[nH]1 CHEMBL3704637 Ki 3.8 nM
N[C@@H]1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)C1 CHEMBL3695285 Ki 4.0 nM
CC12CC3CC(C)(C1)CC(N1[C@@H]4CC[C@H]1C[C@@H](n1c(=O)c(C(=O)O)nc5ccccc51)C4)(C3)C2 CHEMBL3698892 Ki 4.1 nM
COc1cnc(-c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@H]2C[C@@H]3CCC[C@@H](C3)C2)cn1 CHEMBL3704639 Ki 4.11 nM
COc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698764 Ki 4.2 nM
Cc1cc(-c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@H]2C[C@@H]3CCC[C@@H](C3)C2)no1 CHEMBL3704643 Ki 4.2 nM
O=C(O)CN(CCNc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O)CC(=O)O CHEMBL3695249 Ki 4.4 nM
Cc1ccc2[nH]c3c(c2c1)CC(C)OC31CCC(c2ccccc2)(N(C)C)CC1 CHEMBL3892273 Ki 4.4 nM
NC(=O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3695218 Ki 4.42 nM
c1ccc2c(c1)nc(Cc1cnccn1)n2[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704636 Ki 4.5 nM
Cc1ccc2[nH]c3c(c2c1)CCOC31CCC(c2ccccc2)(N(C)C)CC1 CHEMBL3914982 Ki 4.5 nM
O=C(O)CN1CC(c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)C1 CHEMBL3704580 Ki 4.73 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2C3CCCC2CCC3)c1=O CHEMBL3698903 Ki 4.8 nM
c1ccc2c(c1)nc(-c1cc[nH]n1)n2[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704645 Ki 4.9 nM
c1ccc2c(c1)nc(-c1nnn[nH]1)n2[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704616 Ki 5.1 nM
c1ccc2c(c1)nc(C[C@H]1COCCN1)n2[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704631 Ki 5.4 nM
CC1(C)[C@H]2CC[C@@H](CCN3[C@@H]4CCC[C@H]3C[C@@H](n3c(=O)c(N5CC(C(=O)O)C5)nc5ccccc53)C4)[C@@H]1C2 CHEMBL3926298 Ki 5.46 nM
O=c1c(NCC(O)CO)nc2ccccc2n1[C@H]1C[C@H]2CC[C@@H](C1)N2C1CCCCCCC1 CHEMBL3695217 Ki 5.54 nM
O=c1c(N2CCc3ccccc32)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3695272 Ki 5.7 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CC3CCCC(C3)C2)c1=O CHEMBL3647959 Ki 5.7 nM
COc1ccc2[nH]c3c(c2c1)CCOC31CCC(c2ccccc2)(N(C)C)CC1 CHEMBL3924497 Ki 5.8 nM
c1ccc2c(c1)nc(-c1c[nH]cn1)n2[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704644 Ki 6.0 nM
CS(=O)(=O)NCCN1CC[C@@H](Cc2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)C1 CHEMBL3704627 Ki 6.14 nM
NC(=O)CNc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698778 Ki 6.42 nM
O=c1c(NC[C@@H](O)CO)nc2ccccc2n1[C@H]1C[C@H]2CC[C@@H](C1)N2C1CCCCCCC1 CHEMBL3698782 Ki 6.5 nM
C[C@@H]1C[C@@H]2C[C@H](C1)C[C@@H](N1[C@@H]3CCC[C@H]1C[C@@H](n1c(=O)c(N4CC[C@H]4C(=O)O)nc4ccccc41)C3)C2 CHEMBL3894621 EC50 6.54 nM
Cn1cc(Cl)c(-c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)n1 CHEMBL3704646 Ki 6.7 nM
CN(C)C1(c2ccccc2)CCC2(CC1)NCCc1c2[nH]c2cc(F)ccc12 CHEMBL3899983 Ki 6.9 nM
N=C(N)NCCNc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3695262 Ki 7.1 nM
c1ccc2c(c1)nc(-c1ccno1)n2[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@H]1C[C@@H]2CCC[C@@H](C2)C1 CHEMBL3704642 Ki 7.1 nM
CC12C[C@H]3C[C@@H](N4[C@@H]5CCC[C@H]4C[C@@H](n4c(=O)c(N6CC[C@H]6C(=O)O)nc6ccccc64)C5)C[C@@H]1C[C@@H]2C3 CHEMBL4114020 Ki 7.44 nM
O=C(Nc1ccc(=O)[nH]c1)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3695237 Ki 7.5 nM
CN(C)C1(C(=O)O)CCN(c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)CC1 CHEMBL3698809 Ki 7.7 nM
CC12C[C@H]3C[C@@H](N4[C@@H]5CCC[C@H]4C[C@@H](n4c(=O)c(N6CC(C(=O)O)C6)nc6ccccc64)C5)C[C@@H]1C[C@@H]2C3 CHEMBL4113014 EC50 7.8 nM
O=C(O)[C@H](CO)Nc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3695220 Ki 8.2 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3C2C3CCCC2CCC3)c1=O CHEMBL3698901 Ki 8.5 nM
Cn1ccnc1CN1CCOC[C@H]1Cc1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704633 Ki 8.5 nM
N[C@H]1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)C1 CHEMBL3695273 Ki 8.6 nM
O=c1c(N2CC3CNCC3C2)nc2ncccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3698858 Ki 8.6 nM
CC1(N2[C@@H]3CCC[C@H]2C[C@@H](n2c(=O)c(C(=O)O)nc4ccccc42)C3)CCCCCCC1 CHEMBL3698813 Ki 8.6 nM
O=C(O)CCN1CC(c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)C1 CHEMBL3704581 Ki 8.9 nM
O=C(N[C@H](C(=O)O)c1ccccc1)c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698816 Ki 9.0 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCCCCC2)c1=O CHEMBL3647960 Ki 9.0 nM
O=C(O)CN1CCC[C@@H]1c1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704584 Ki 9.0 nM
C[C@@H]1C[C@@H]2C[C@H](C1)C[C@@H](N1[C@@H]3CCC[C@H]1C[C@@H](n1c(=O)c(N4CC[C@@H]4C(=O)O)nc4ccccc41)C3)C2 CHEMBL4115055 Ki 9.8 nM
CCOC(=O)c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3C(C)CC(C)C)c1=O CHEMBL3698818 Ki 9.9 nM
O=C(O)C1CN(c2nc3ccccc3n([C@H]3C[C@H]4CCC[C@@H](C3)N4C3CCCCCCCCC3)c2=O)C1 CHEMBL3962669 Ki 9.93 nM
CNC1(c2ccccc2)CCC2(CC1)OCCc1c2[nH]c2ccc(F)cc12 CHEMBL3909973 Ki 10.0 nM
CCOC(=O)c1nc2ccccc2n([C@@H]2C[C@H]3CCC[C@@H](C2)N3C/C=C2\CCC3CC2C3(C)C)c1=O CHEMBL3984664 Ki 10.5 nM
O=C(O)C(CO)NCCNc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698862 Ki 10.6 nM
NC1(C(=O)O)CCN(c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)C1 CHEMBL3698874 Ki 10.6 nM
O=C(NO)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698781 Ki 10.71 nM
O=C1NC(=O)C2(CCN(c3nc4ccccc4n([C@H]4C[C@H]5CC[C@@H](C4)N5C4CCCCCCC4)c3=O)CC2)N1 CHEMBL3695254 Ki 10.9 nM
NC(=O)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698768 Ki 10.9 nM
NC1(C(=O)O)CCN(c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)CC1 CHEMBL3695256 Ki 11.1 nM
O=C(NC(Cc1ccccc1)C(=O)O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698907 Ki 11.5 nM
CS(=O)(=O)NCCN1CCC[C@@H](Cc2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)C1 CHEMBL3704626 Ki 11.5 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CCCC[C@@H](C2)N3C2/C=C\CCCCC2)c1=O CHEMBL3698825 Ki 11.6 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C23CC4CC(CC(C4)C2)C3)c1=O CHEMBL3695245 Ki 11.9 nM
CO[C@H]1CN(c2nc3ccccc3n([C@H]3C[C@H]4CCC[C@@H](C3)N4[C@H]3C[C@@H]4CCC[C@@H](C4)C3)c2=O)[C@@H]1C(=O)O CHEMBL3985683 Ki 11.9 nM
N[C@@H]1CN(c2nc3ccccc3n([C@H]3C[C@H]4CCC[C@@H](C3)N4[C@H]3C[C@@H]4CCC[C@@H](C4)C3)c2=O)[C@@H]1C(=O)O CHEMBL4113102 Ki 11.9 nM
O=C(NCC(O)CO)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3695240 Ki 12.0 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698765 Ki 12.6 nM
O=C(NOCc1ccccc1)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698775 Ki 12.7 nM
O=C(NC(CO)C(=O)O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3695244 Ki 13.5 nM
COc1ccc(NC(=O)c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)cn1 CHEMBL3698771 Ki 13.7 nM
CC(C)CC(C)N1[C@@H]2CCC[C@H]1C[C@@H](n1c(=O)c(C(=O)O)nc3ccccc31)C2 CHEMBL3698820 Ki 13.8 nM
NCCNc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698840 Ki 14.2 nM
O=C(O)CN1CCC(Cc2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)CC1 CHEMBL3704597 Ki 14.2 nM
O=C1CN(c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)CCN1 CHEMBL3698861 Ki 14.6 nM
NCC(O)CNc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698753 Ki 14.8 nM
CS(=O)(=O)NCCN1CCC[C@H]1Cc1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704620 Ki 14.9 nM
CC12C[C@H]3C[C@@H](N4[C@@H]5CCC[C@H]4C[C@@H](n4c(=O)c(N6CCC[C@H]6C(=O)O)nc6ccccc64)C5)C[C@@H]1C[C@@H]2C3 CHEMBL4112615 Ki 15.0 nM
Nc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698846 Ki 15.4 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C23CC4CC(CC2C4)C3)c1=O CHEMBL3698801 Ki 15.4 nM
CS(=O)(=O)N[C@@H]1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)C1 CHEMBL3698761 Ki 15.5 nM
C[C@@]12CC[C@@H](C[C@@H](n3c(=O)c(C(=O)NCC(=O)O)nc4ccccc43)C1)N2C1CCCCCCC1 CHEMBL3695243 Ki 15.7 nM
NC(=O)CN1CCC[C@H](c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)C1 CHEMBL3704593 Ki 15.7 nM
O=C(O)CN1CC2CN(c3nc4ccccc4n([C@H]4C[C@H]5CC[C@@H](C4)N5C4CCCCCCC4)c3=O)CC2C1 CHEMBL3698869 Ki 15.8 nM
CCN(CC)C(=O)CN1CC[C@@H](Cc2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)C1 CHEMBL3704629 Ki 15.8 nM
O=C(Nc1ccc(=O)[nH]c1)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698773 Ki 16.2 nM
O=C(O)C1(O)CCN(c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)CC1 CHEMBL3695253 Ki 16.3 nM
NC(=O)CN(CCNc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O)CC(=O)O CHEMBL3698865 Ki 16.8 nM
O=c1c(N2Cc3ccccc3C2)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3698849 Ki 16.8 nM
O=C(O)CN1CCC[C@H]1Cc1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704623 Ki 17.0 nM
CCOC(=N)/N=c1\[nH]c2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3704607 Ki 17.5 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698878 Ki 17.7 nM
CC1(N2CCC(n3c(=O)c(C(=O)O)nc4ccccc43)CC2)CCCCCCC1 CHEMBL3698890 Ki 18.1 nM
O=C(O)CN1CCC[C@H]1c1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704583 Ki 18.2 nM
CC(=O)N[C@@H]1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)C1 CHEMBL3695271 Ki 18.6 nM
O=C(O)CN1CC[C@H](c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)C1 CHEMBL3704585 Ki 18.6 nM
CONC(=O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3695236 Ki 18.9 nM
NC(=O)CN1CCC[C@H]1c1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704588 Ki 19.0 nM
O=c1c(NC(CO)CO)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3698762 Ki 19.1 nM
C[C@@H]1C[C@@H]2C[C@H](C1)C[C@@H](N1[C@@H]3CC[C@H]1C[C@@H](n1c(=O)c(N4CC[C@H]4C(=O)O)nc4ccccc41)C3)C2 CHEMBL3942346 Ki 19.2 nM
O=c1c(N2CC3CNCC3C2)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3698836 Ki 19.4 nM
O=C(O)CCN1CCC[C@H]1Cc1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704634 Ki 19.9 nM
O=C(O)CNCCNc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3639941 Ki 20.4 nM
N#Cc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698776 Ki 20.8 nM
O=c1cc(-c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)[nH]c(=O)[nH]1 CHEMBL3704647 Ki 20.8 nM
CN1CC2CN(c3nc4ccccc4n(C4CCN(C5CCCCCCC5)CC4)c3=O)CC2C1 CHEMBL3698843 Ki 20.9 nM
CN(C(=O)O)[C@@H]1CCN(c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)C1 CHEMBL3698897 Ki 21.5 nM
c1ccc2c(c1)nc(-c1cnccn1)n2[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@H]1C[C@@H]2CCC[C@@H](C2)C1 CHEMBL3704640 Ki 21.6 nM
O=C(O)CN1CCC/C(=C2/N(CC(=O)O)c3ccccc3N2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)C1 CHEMBL3704594 Ki 21.7 nM
CCOC(=O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698884 Ki 22.2 nM
CONC(=N)/N=c1\[nH]c2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3704609 Ki 22.4 nM
NC(=O)[C@H](CO)Nc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3695269 Ki 22.9 nM
CN(CC(=O)O)[C@H]1CCN(c2nc3ccccc3n([C@H]3C[C@H]4CCC[C@@H](C3)N4C3CCCCCCC3)c2=O)C1 CHEMBL3698821 Ki 22.9 nM
CC1Cc2c([nH]c3ccc(Br)cc23)C2(CCC(c3ccccc3)(N(C)C)CC2)O1 CHEMBL3973336 Ki 23.0 nM
CN(C)[C@@H]1CN(c2nc3ccccc3n([C@H]3C[C@H]4CCC[C@@H](C3)N4[C@H]3C[C@@H]4CCC[C@@H](C4)C3)c2=O)[C@@H]1C(=O)O CHEMBL4109756 Ki 23.0 nM
O=C(O)CCN1CCC(Cc2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)CC1 CHEMBL3704598 Ki 23.5 nM
CC1(C)[C@H]2CC[C@@H](CCN3[C@@H]4CCC[C@H]3C[C@@H](n3c(=O)c(N5CC[C@H]5C(=O)O)nc5ccccc53)C4)[C@@H]1C2 CHEMBL3957299 Ki 23.6 nM
O=C(O)[C@@H](CO)Nc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3695230 Ki 23.8 nM
O=c1c(NC[C@H](O)CO)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3698750 Ki 24.1 nM
O=C(N[C@H](C(=O)O)c1ccccc1)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698793 Ki 24.6 nM
CCOC(=O)[C@@H]1CN(CCNc2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)C[C@H]1C(=O)OCC CHEMBL3698807 Ki 24.6 nM
O=C(O)CN1CCN(c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)CC1 CHEMBL3698786 Ki 26.5 nM
C=CCNc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698850 Ki 27.0 nM
O=C(O)[C@@H]1CCN1c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3[C@H]2C[C@@H]3CCC[C@@H](C3)C2)c1=O CHEMBL3970857 Ki 27.1 nM
O=C(O)C1CCN(Cc2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@H]2C[C@@H]3CCC[C@@H](C3)C2)CC1 CHEMBL3704605 Ki 27.7 nM
CC1Cc2c([nH]c3ccc([N+](=O)[O-])cc23)C2(CCC(c3ccccc3)(N(C)C)CC2)O1 CHEMBL3942233 Ki 29.0 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3C23CC4CC(CC(C4)C2)C3)c1=O CHEMBL3698893 Ki 29.1 nM
O=C(O)CN1CCCC[C@H]1Cc1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704635 Ki 29.5 nM
CCOC(=O)c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3C(C)CCC(C)C)c1=O CHEMBL3698817 Ki 29.8 nM
O=C(O)N[C@@H]1CCN(c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)C1 CHEMBL3698895 Ki 29.9 nM
CC(=O)N[C@H]1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)C1 CHEMBL3698754 Ki 29.9 nM
CCC1(N2CCC(n3c(=O)c(C(=O)O)nc4ccccc43)CC2)CCCCCCC1 CHEMBL3889570 Ki 30.2 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3C23CCCC(CCC2)C3)c1=O CHEMBL3647961 Ki 30.2 nM
O=c1c(NC[C@@H](O)CO)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3695288 Ki 31.9 nM
Cc1ccc2[nH]c3c(c2c1)CCNC31CCC(c2ccccc2)(N(C)C)CC1 CHEMBL3979202 Ki 32.0 nM
COC(=O)C(CO)Nc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3695280 Ki 32.1 nM
O=C(NC(Cc1c[nH]cn1)C(=O)O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698906 Ki 33.5 nM
O=C(O)C1CCN(CCNc2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)CC1 CHEMBL3939135 Ki 34.7 nM
NC1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)CC1 CHEMBL3695260 Ki 35.2 nM
CS(=O)(=O)N1CCC(Nc2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)CC1 CHEMBL3695284 Ki 35.2 nM
CC(C)CCC(C)N1[C@@H]2CCC[C@H]1C[C@@H](n1c(=O)c(C(=O)O)nc3ccccc31)C2 CHEMBL3698819 Ki 35.4 nM
CC(C)CC(NC(=O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O)C(=O)O CHEMBL3698795 Ki 35.8 nM
CC(NC(=O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O)C(=O)O CHEMBL3698794 Ki 35.9 nM
O=C(O)CCN1CC[C@@H](Cc2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)C1 CHEMBL3704625 Ki 36.0 nM
O=C(O)[C@H](CO)Nc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698751 Ki 36.5 nM
NC(=O)/N=c1\[nH]c2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3704608 Ki 36.7 nM
O=c1c(NC2CCNCC2)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3695267 Ki 36.9 nM
NC(=O)[C@@H]1CCCN1c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3695276 Ki 36.9 nM
COC(=O)/N=c1\n(CC(N)=O)c2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3704610 Ki 37.1 nM
NC(=O)CNc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3695268 Ki 37.4 nM
O=C(O)CN1CCC[C@@H]1c1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2C1CCCCCCCCC1 CHEMBL3704577 Ki 37.9 nM
O=C(O)[C@@H](Nc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O)c1ccccc1 CHEMBL3695251 Ki 39.6 nM
NC(=O)C1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)CC1 CHEMBL3695265 Ki 39.8 nM
CC(=O)N[C@@H]1CN(c2nc3ccccc3n([C@H]3C[C@H]4CCC[C@@H](C3)N4[C@H]3C[C@@H]4CCC[C@@H](C4)C3)c2=O)[C@@H]1C(=O)O CHEMBL4110868 Ki 39.9 nM
Cc1nc(C)c(-c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@H]2C[C@@H]3CCC[C@@H](C3)C2)s1 CHEMBL3704641 Ki 40.0 nM
CCOC(=O)c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698877 Ki 40.3 nM
CNC(=O)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698769 Ki 40.7 nM
O=c1c(N2CC[C@@H](O)C2)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3698779 Ki 41.2 nM
O=c1c(N2CCc3ccccc3C2)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3695277 Ki 42.3 nM
NC(=O)CCNc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3695281 Ki 42.4 nM
O=C(O)CN1CCC(c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)CC1 CHEMBL3704595 Ki 42.7 nM
C[C@@H]1C[C@@H]2C[C@H](C1)C[C@@H](N1[C@@H]3CC[C@H]1C[C@@H](n1c(=O)c(N4CC[C@@H]4C(=O)O)nc4ccccc41)C3)C2 CHEMBL4111642 Ki 43.0 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCCCCCC2)c1=O CHEMBL3647963 Ki 43.1 nM
O=C(O)CN1CCC[C@H](c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)C1 CHEMBL3704591 Ki 43.4 nM
C[C@]12CC[C@H](C[C@H](N3C(=O)C(N[C@@H](CO)C(=O)O)Nc4ccccc43)C1)N2C1CCCCCCC1 CHEMBL3898898 Ki 43.7 nM
CN(C)C(=O)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698772 Ki 44.0 nM
CONC(=O)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698774 Ki 44.0 nM
NC(=O)C1(N2CCC(n3c(=O)c(N4CC5CNCC5C4)nc4ccccc43)CC2)CCCCCCC1 CHEMBL3695248 Ki 44.6 nM
O=C(O)N1CCN(c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)CC1=O CHEMBL3698868 Ki 44.8 nM
CCOC(=O)CNc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698752 Ki 45.0 nM
CCCC1(N2CCC(n3c(=O)c(C(=O)O)nc4ccccc43)CC2)CCCCCCC1 CHEMBL3698894 Ki 45.5 nM
O=C(O)CN1CCCC[C@H]1c1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704589 Ki 45.5 nM
O=C(O)C1(O)CCN(c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)C1 CHEMBL3698864 Ki 46.1 nM
O=c1ccc(Nc2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)c[nH]1 CHEMBL3695279 Ki 46.3 nM
c1ccc2c(c1)nc(Cc1nnn[nH]1)n2[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704638 Ki 47.2 nM
CCN(CC)C(=O)CN1CCC[C@@H](Cc2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)C1 CHEMBL3704628 Ki 47.9 nM
COC(=O)[C@@H]1CCCN1c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3695263 Ki 48.5 nM
O=c1c(N2CC[C@H](O)C2)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3698763 Ki 49.8 nM
CC(C)CC(C)N1[C@@H]2CC[C@H]1C[C@@H](n1c(=O)c(C(=O)O)nc3ccccc31)C2 CHEMBL3698828 Ki 50.0 nM
O=C(NCC(O)CO)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698770 Ki 51.0 nM
CN(C)C1(c2ccccc2)CCC2(CC1)OCCc1c2[nH]c2ccc(Br)cc12 CHEMBL3895920 Ki 52.0 nM
O=C(O)CC1CCN(c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)C1 CHEMBL3695229 Ki 52.1 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2Cc3cccc4cccc2c34)c1=O CHEMBL3698889 Ki 52.1 nM
O=C(c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O)N1CC2CNCC2C1 CHEMBL3698855 Ki 52.8 nM
NC(=O)CNc1nc2ccccc2n(C2CCN(C34CC5CC(CC(C5)C3)C4)CC2)c1=O CHEMBL3698759 Ki 54.8 nM
O=C(O)CN1CCCC[C@@H]1c1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704590 Ki 55.0 nM
CC12C[C@H]3C[C@@H](N4[C@@H]5COC[C@H]4C[C@@H](n4c(=O)c(N6CC[C@H]6C(=O)O)nc6ccccc64)C5)C[C@@H]1C[C@@H]2C3 CHEMBL4112220 Ki 55.5 nM
CS(=O)(=O)NC1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)CC1 CHEMBL3695266 Ki 57.9 nM
O=C(O)CNc1nc2ccccc2n1C1C[C@H]2CCC[C@@H](C1)N2C1CCCCCCCCC1 CHEMBL3704612 Ki 59.1 nM
O=C(O)c1ccc(CNC(=O)c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)cc1 CHEMBL3698796 Ki 59.7 nM
O=C(O)CNC(=O)CNc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3695255 Ki 60.4 nM
CC(=O)NC1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)CC1 CHEMBL3695261 Ki 60.8 nM
O=C(O)c1ccc(CNC(=O)c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)nc1 CHEMBL3698799 Ki 60.8 nM
O=C(O)CNc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3695224 Ki 61.4 nM
O=C(O)CN(CCO)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698876 Ki 61.7 nM
CN(C)C1(c2ccc(F)cc2)CCC2(CC1)c1sc3ccccc3c1CC[S+]2[O-] CHEMBL3936891 Ki 62.0 nM
CCOC(=O)C1CN(CCNc2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)C[C@H]1C(=O)OCC CHEMBL3698810 Ki 62.2 nM
CSCCC(NC(=O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O)C(=O)O CHEMBL3698791 Ki 62.9 nM
O=C(O)CNc1nc2ccccc2n1C1C[C@H]2CCC[C@@H](C1)N2[C@H]1C[C@@H]2CCC[C@@H](C2)C1 CHEMBL3704611 Ki 65.0 nM
O=c1c(NCC(O)CO)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3698851 Ki 65.7 nM
CC1(C)[C@H]2CC[C@@H](CCN3[C@@H]4CCC[C@H]3C[C@@H](n3c(=O)c(N5CC[C@@H]5C(=O)O)nc5ccccc53)C4)[C@@H]1C2 CHEMBL3920823 EC50 65.7 nM
O=C(O)CN1CCN(Cc2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@H]2C[C@@H]3CCC[C@@H](C3)C2)CC1 CHEMBL3704606 Ki 66.0 nM
O=C(O)c1cc(CNc2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)ccc1O CHEMBL3698811 Ki 66.1 nM
CN(C)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698834 Ki 67.2 nM
CC(=O)N1CCC(Nc2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)CC1 CHEMBL3695283 Ki 70.9 nM
O=C(O)C(=O)N1CC2CN(c3nc4ccccc4n(C4CCN(C5CCCCCCC5)CC4)c3=O)CC2C1 CHEMBL3698872 Ki 71.4 nM
O=c1c(N2CCNCC2)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3698841 Ki 72.1 nM
O=C1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)N1 CHEMBL3695234 Ki 73.2 nM
CC(C)(Nc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O)C(=O)O CHEMBL3698866 Ki 74.5 nM
CC(C)(C)OC(=O)NC1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)CC1 CHEMBL3695259 Ki 74.8 nM
O=c1c(NC[C@@H](O)CO)nc2ccccc2n1C1CCN(C23CC4CC(CC(C4)C2)C3)CC1 CHEMBL3698777 Ki 75.2 nM
CC(C)(NC(=O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O)C(=O)O CHEMBL3698790 Ki 77.5 nM
O=C(O)[C@H](Cc1ccccc1)Nc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3695252 Ki 78.8 nM
O=C(O)CN(CCNC(=O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C23CC4CC(CC(C4)C2)C3)c1=O)CC(=O)O CHEMBL3698806 Ki 82.0 nM
CC1Cc2c([nH]c3ccc(F)cc23)C2(CCC(c3ccccc3)(N(C)C)CC2)O1 CHEMBL3983394 Ki 83.0 nM
CN(CC(O)CO)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698760 Ki 85.3 nM
O=C(O)CCN1CC[C@H](c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)C1 CHEMBL3704587 Ki 86.0 nM
O=C(O)CCN1CCC[C@H](c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)C1 CHEMBL3704592 Ki 86.0 nM
O=c1c(N2CCC(O)CC2)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3695286 Ki 92.0 nM
O=C(O)CCN1CCC(c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)CC1 CHEMBL3704596 Ki 92.0 nM
O=C1CNc2ccccc2N1C1CCN(C2CCCCCCC2)CC1 CHEMBL3698856 Ki 92.2 nM
O=C(O)[C@H]1CCN1c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3[C@H]2C[C@@H]3CCC[C@@H](C3)C2)c1=O CHEMBL4109187 Ki 93.5 nM
CC(=O)N1CC2CN(c3nc4ccccc4n(C4CCN(C5CCCCCCC5)CC4)c3=O)CC2C1 CHEMBL3698844 Ki 96.5 nM
O=C(O)CCN1CCC[C@@H]1c1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704586 Ki 96.9 nM
COC(=O)C1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)CC1 CHEMBL3695257 Ki 97.8 nM
O=C(O)[C@@H]1CCCN1c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3[C@H]2C[C@@H]3CCC[C@@H](C3)C2)c1=O CHEMBL3895142 Ki 98.0 nM
O=C(O)CC1CCN(c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)CC1 CHEMBL3698873 Ki 101.9 nM
O=C(O)CO/N=C/c1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@H]1C[C@@H]2CCC[C@@H](C2)C1 CHEMBL3704614 Ki 102.0 nM
O=C(Nc1ccc(=O)[nH]c1)c1nc2ccccc2n([C@@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3695239 Ki 103.0 nM
O=C(O)[C@@H]1CN(CCNc2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)C[C@H]1C(=O)O CHEMBL3698808 Ki 104.2 nM
O=C(O)C1CCN(c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)CC1 CHEMBL3695219 Ki 109.0 nM
CCOC(=O)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698852 Ki 109.0 nM
COC(=O)c1ccc2c(c1)CN(c1nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c1=O)CC2 CHEMBL3695278 Ki 111.0 nM
O=C(O)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698853 Ki 111.0 nM
CS(=O)(=O)NCCNc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698842 Ki 114.9 nM
O=C(O)C1CCCN1C(=O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698788 Ki 114.9 nM
COCCOCCOCCN1CCC[C@H](c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@H]2C[C@@H]3CCC[C@@H](C3)C2)C1 CHEMBL3704600 Ki 117.0 nM
O=C(O)CCN1CCC[C@@H](Cc2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)C1 CHEMBL3704624 Ki 117.0 nM
CC(C)(C)OC(=O)N1CC2CN(c3nc4ccccc4n(C4CCN(C5CCCCCCC5)CC4)c3=O)CC2C1 CHEMBL3695216 Ki 117.5 nM
O=C(O)CN1CCC[C@@H](Cc2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@@H]2C[C@@H]3CCCC[C@@H](C3)C2)C1 CHEMBL3704622 Ki 120.0 nM
NC(=O)[C@H](CO)Nc1nc2ccccc2n([C@@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3695222 Ki 120.1 nM
O=C(O)CC(NC(=O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O)C(=O)O CHEMBL3698792 Ki 127.6 nM
COc1ccc(NC(=O)c2nc3ccccc3n([C@@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)cn1 CHEMBL3695238 Ki 127.7 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C23CCC(CC2)C3)c1=O CHEMBL3698823 Ki 128.0 nM
NC(=O)C1CCCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)C1 CHEMBL3698755 Ki 130.0 nM
CCOC(=O)CN(C)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698756 Ki 130.0 nM
CC(C)C1CCC(N2[C@@H]3CC[C@H]2C[C@@H](n2c(=O)c(C(=O)O)nc4ccccc42)C3)CC1 CHEMBL3698879 Ki 131.4 nM
O=C(O)c1nc2ccc(F)cc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698785 Ki 135.9 nM
O=C(O)C1CCCN1C(=O)CNc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698870 Ki 140.0 nM
O=C(O)Cc1csc(NC(=O)c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)n1 CHEMBL3698891 Ki 144.0 nM
CO[C@]12CC[C@@]3(C[C@@H]1COCc1ccccc1)[C@H]1Cc4ccc(O)c5c4[C@@]3(CCN1)[C@H]2O5 CHEMBL4111231 Ki 145.03 nM
COc1ccc2c3c1O[C@H]1[C@@]4(OC)CC[C@@]5(C[C@@H]4CNCc4ccccc4)[C@@H](C2)N(CC2CC2)CC[C@]315 CHEMBL4113058 Ki 147.0 nM
O=C(O)c1cccc(CNc2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)c1 CHEMBL3698787 Ki 149.0 nM
O=c1c(NCc2ccccc2)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3698837 Ki 152.0 nM
COc1ccc(Nc2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)cn1 CHEMBL3695270 Ki 153.0 nM
O=c1c(NCCO)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3698835 Ki 153.7 nM
CC(C)(C)OC(=O)NCCNc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698838 Ki 156.0 nM
COC(=O)[C@@H]1C[C@@H](O)CN1c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3695264 Ki 156.3 nM
O=C(NCc1nn[nH]n1)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698798 Ki 157.0 nM
CC(=O)NC1(C(=O)O)CCN(c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)CC1 CHEMBL3698863 Ki 158.0 nM
CCN(CC)C(=O)CN1CCC[C@H]1Cc1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704621 Ki 167.1 nM
CN(CC(=O)O)C(=O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698789 Ki 170.0 nM
N[C@]12CCC[C@H](C[C@H](n3c(=O)c(C(=O)O)nc4ccccc43)C1)N2C1CC2CCCC(C2)C1 CHEMBL4114883 Ki 178.0 nM
O=C1CN(C2CCN(C3CCCCCCC3)CC2)c2ccccc2N1 CHEMBL3698857 Ki 179.4 nM
CC(=O)Nc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698847 Ki 181.8 nM
O=C1CN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)CCN1 CHEMBL3698848 Ki 182.0 nM
COCCOCCOCCN1CCC[C@@H](c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@H]2C[C@@H]3CCC[C@@H](C3)C2)C1 CHEMBL3704599 Ki 182.0 nM
CO[C@]12CC[C@@]3(C[C@@H]1COCc1ccccc1)[C@H]1Cc4ccc(NC(C)=O)c5c4[C@@]3(CCN1C)[C@H]2O5 CHEMBL4110440 Ki 187.98 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3CCC2CCCCC2)c1=O CHEMBL3698833 Ki 188.0 nM
O=C(O)Cc1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3695228 Ki 189.0 nM
O=C(O)c1nc2ccccc2n(C2CC3CCC(C2)N3C2CC3CCCC(C3)C2)c1=O CHEMBL3906430 Ki 202.8 nM
CCC(C#CC(C)(C)C)N1[C@@H]2CC[C@H]1C[C@@H](n1c(=O)c(C(=O)O)nc3ccccc31)C2 CHEMBL3698804 Ki 205.0 nM
CC(C)(C)OC(=O)N1CC2CN(C(=O)c3nc4ccccc4n(C4CCN(C5CCCCCCC5)CC4)c3=O)CC2C1 CHEMBL3698854 Ki 220.0 nM
O=C(O)CN1CCC[C@H](c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@H]2C[C@@H]3CCC[C@@H](C3)C2)C1 CHEMBL3704576 Ki 220.0 nM
CO[C@]12CC[C@@]3(C[C@@H]1CNC(=O)[C@@H](N)Cc1ccccc1)[C@H]1Cc4ccc(O)c5c4[C@@]3(CCN1CC1CC1)[C@H]2O5 CHEMBL3691854 Ki 228.55 nM
NC(=O)CNc1nc2ccccc2n([C@@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698783 Ki 233.7 nM
O=C(O)C1(Nc2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)CCCCC1 CHEMBL3698867 Ki 237.3 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3C2C3CC4CC(C3)CC2C4)c1=O CHEMBL3698826 Ki 250.0 nM
O=C(O)CN1CCN(c2nc3ccccc3n2[C@H]2C[C@H]3CCC[C@@H](C2)N3[C@H]2C[C@@H]3CCC[C@@H](C3)C2)CC1 CHEMBL3704603 Ki 251.0 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3COC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698882 Ki 260.0 nM
CO[C@]12CC[C@@]3(C[C@@H]1COCc1ccccc1)[C@H]1Cc4ccc(F)c5c4[C@@]3(CCN1CC1CC1)[C@H]2O5 CHEMBL4108017 EC50 260.98 nM
CC12C[C@H]3C[C@@H](N4[C@@H]5COC[C@H]4C[C@@H](n4c(=O)c(N6CC(CC(=O)O)C6)nc6ccccc64)C5)C[C@@H]1C[C@@H]2C3 CHEMBL4108614 Ki 264.0 nM
CC12C[C@H]3C[C@@H](N4[C@@H]5COC[C@H]4C[C@@H](n4c(=O)c(N6CCC[C@H]6C(=O)O)nc6ccccc64)C5)C[C@@H]1C[C@@H]2C3 CHEMBL4108395 Ki 272.0 nM
N#CNC(=O)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698766 Ki 273.0 nM
O=C(O)c1nc2ccccc2n([C@@H]2C[C@H]3CC[C@@H](C2)N3C23CC4CC(CC(C4)C2)C3)c1=O CHEMBL3695246 Ki 275.0 nM
O=C(O)[C@H](CO)Nc1nc2ccccc2n([C@@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3695225 Ki 285.0 nM
CO[C@]12CC[C@@]3(C[C@@H]1COCc1ccccc1)[C@H]1Cc4ccc(F)c5c4[C@@]3(CCN1C)[C@H]2O5 CHEMBL4107906 Ki 286.22 nM
O=c1c(NC[C@@H](O)CO)nc2ccccc2n1[C@@H]1C[C@H]2CC[C@@H](C1)N2C1CCCCCCC1 CHEMBL3695223 Ki 288.0 nM
CC(C)(C1CCCCCCC1)N1[C@@H]2CCC[C@H]1C[C@@](C)(n1c(=O)c(C(=O)O)nc3ccccc31)C2 CHEMBL3917702 Ki 289.0 nM
O=C(O)[C@@H]1CCN1c1nc2ccccc2n([C@H]2C[C@H]3COC[C@@H](C2)N3[C@H]2C[C@@H]3CCC[C@@H](C3)C2)c1=O CHEMBL3931558 Ki 294.0 nM
O=C(O)c1nc2ccccc2n([C@@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698780 Ki 299.0 nM
CC(C)(C)OC(=O)Nc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698845 Ki 301.0 nM
O=C(O)C1CCCN1c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3695274 Ki 309.0 nM
CC(C)(C)OC(=O)N1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)CC1 CHEMBL3698839 Ki 322.0 nM
O=c1c(N2CCOCC2)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3695215 Ki 326.1 nM
O=C(O)c1ccc2c(c1)CN(c1nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c1=O)CC2 CHEMBL3695287 Ki 332.0 nM
CO[C@]12CC[C@@]3(C[C@@H]1COCc1ccccc1C)[C@H]1Cc4ccc(OCCO)c5c4[C@@]3(CCN1C)[C@H]2O5 CHEMBL4111224 Ki 332.93 nM
O=c1c(Nc2ccccc2)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 CHEMBL3695282 Ki 355.0 nM
O=C(O)c1nc2ccccc2n([C@@H]2C[C@H]3CC[C@@H](C2)N3C23CC4CC(CC2C4)C3)c1=O CHEMBL3698824 Ki 364.0 nM
O=C(O)CNc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698757 Ki 368.0 nM
CCOC(=O)c1nc2ccccc2n([C@H]2C[C@H]3CCC[C@@H](C2)N3C2CCC(C)(C)CC2)c1=O CHEMBL3698829 Ki 374.0 nM
CS(=O)(=O)NC(=O)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698767 Ki 375.0 nM
CC12C[C@H]3C[C@@H](N4[C@@H]5COC[C@H]4C[C@@H](n4c(=O)c(N6CC(C(=O)O)C6)nc6ccccc64)C5)C[C@@H]1C[C@@H]2C3 CHEMBL4107307 Ki 381.0 nM
O=C(O)CCNC(=O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698905 Ki 382.0 nM
CCC(C#CC(C)C)N1[C@@H]2CC[C@H]1C[C@@H](n1c(=O)c(C(=O)O)nc3ccccc31)C2 CHEMBL3698888 Ki 383.0 nM
CC1(C)[C@H]2CC[C@@H](CN3[C@@H]4CC[C@H]3C[C@@H](n3c(=O)c(C(=O)O)nc5ccccc53)C4)[C@@H]1C2 CHEMBL3698805 Ki 398.0 nM
O=C(O)C1C[C@@H](O)CN1c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3695275 Ki 426.0 nM
O=C(O)C[C@@H](Nc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O)C(=O)O CHEMBL3695250 Ki 437.0 nM
CN(CC(=O)O)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698758 Ki 438.0 nM
O=C(O)c1ccc(CNc2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)cc1 CHEMBL3705026 Ki 456.0 nM
O=C(O)C1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)C1 CHEMBL3695226 Ki 493.0 nM
CCOC(=O)[C@@H]1CN(CCNc2nc3ccccc3n([C@H]3C[C@H]4CCC[C@@H](C3)N4C34CC5CC(CC3C5)C4)c2=O)C[C@H]1C(=O)OCC CHEMBL3698812 Ki 493.3 nM
CC1(C)CC(N2[C@@H]3CC[C@H]2C[C@@H](n2c(=O)c(C(=O)O)nc4ccccc42)C3)CC(C)(C)C1 CHEMBL3698832 Ki 496.0 nM
O=C(O)CN[C@H]1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)C1 CHEMBL3698859 Ki 500.0 nM
O=C(O)c1ccncc1Nc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698896 Ki 502.0 nM
C[C@@H]1C[C@@H]2C[C@H](C1)C[C@@H](N1[C@@H]3CCC[C@H]1C[C@@H](n1c(N4CCC[C@H]4C(=O)O)nc4ccccc41)C3)C2 CHEMBL3704601 Ki 505.0 nM
O=C(O)[C@@H]1CCCN1c1nc2ccccc2n([C@H]2C[C@H]3COC[C@@H](C2)N3[C@H]2C[C@@H]3CCC[C@@H](CC3)C2)c1=O CHEMBL3910820 Ki 511.0 nM
COc1ccc2c3c1O[C@H]1[C@@]4(OC)CC[C@@]5(C[C@@H]4COCc4ccccc4)[C@@H](C2)N(CC2CC2)CC[C@]315 CHEMBL3916122 Ki 532.0 nM
O=C(O)c1ccccc1Nc1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698875 Ki 538.0 nM
O=C(O)C1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)CC1 CHEMBL3695258 Ki 547.0 nM
CC(Nc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O)C(=O)O CHEMBL3695233 Ki 561.0 nM
COc1ccc2c3c1OC1C4(OC)CCC5(CC4COCc4ccccc4)[C@@H](C2)N(C)CC[C@]315 CHEMBL3664525 Ki 569.0 nM
O=C(O)CN1CCCC[C@@H]1c1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2C1CCCCCCCCC1 CHEMBL3704579 Ki 583.0 nM
O=C(O)[C@@H]1CN(CCNc2nc3ccccc3n(C3CC45CCCC(C3)(C4)N5C34CC5CC(CC3C5)C4)c2=O)C[C@H]1C(=O)O CHEMBL3639976 Ki 587.2 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2Cc3ccccc3C2)c1=O CHEMBL3698885 Ki 596.0 nM
O=C(O)[C@H]1CC[C@@H](Nc2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)C1 CHEMBL3698784 Ki 607.4 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C2C=CCCCC2)c1=O CHEMBL3698800 Ki 611.0 nM
O=C(O)C1CCN(C(=O)c2nc3ccccc3n([C@H]3C[C@H]4CC[C@@H](C3)N4C3CCCCCCC3)c2=O)CC1 CHEMBL3698797 Ki 632.0 nM
O=C(O)CCN1CCC[C@@H]1c1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2C1CCCCCCCCC1 CHEMBL3704578 Ki 690.0 nM
CC(C)C#CC(C(C)C)N1[C@@H]2CC[C@H]1C[C@@H](n1c(=O)c(C(=O)O)nc3ccccc31)C2 CHEMBL3698887 Ki 740.0 nM
Cc1noc(C)c1S(=O)(=O)N1CCC[C@@H]1c1nc2ccccc2n1[C@H]1C[C@H]2CCC[C@@H](C1)N2[C@@H]1C[C@@H]2CCCC[C@@H](C2)C1 CHEMBL3704615 Ki 780.0 nM
O=C(O)CCNc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O CHEMBL3698860 Ki 785.0 nM
COc1ccc2c3c1O[C@H]1[C@@]4(OC)CC[C@@]5(C[C@@H]4COCc4ccc(Cl)c(Cl)c4)[C@@H](C2)N(CC2CC2)CC[C@]315 CHEMBL3923372 Ki 823.29 nM
CC1(C)CCC(N2[C@@H]3CCC[C@H]2C[C@@H](n2c(=O)c(C(=O)O)nc4ccccc42)C3)CC1 CHEMBL3698830 Ki 828.0 nM
Cc1cc(C)nc(SCc2ccc(C(=O)NN/C=C3\C=CC=C(O)C3=O)cc2)n1 CHEMBL3695231 Ki 836.0 nM
COc1ccc2c3c1O[C@H]1[C@@]4(OC)CC[C@@]5(C[C@@H]4COCc4ccccc4)[C@@H](C2)NCC[C@]315 CHEMBL4112656 Ki 883.98 nM
CCOC(=O)c1nc2ccccc2n([C@H]2C[C@H]3COC[C@@H](C2)N3C2CCCCCCC2)c1=O CHEMBL3698881 Ki 911.0 nM
O=C(O)c1nc2ccccc2n([C@H]2C[C@H]3CC[C@@H](C2)N3C23CC4C[C@H](C2)C[C@@](O)(C4)C3)c1=O CHEMBL3900785 Ki 912.0 nM
CC(C)(C)C1CCC(N2[C@@H]3CC[C@H]2C[C@@H](n2c(=O)c(C(=O)O)nc4ccccc42)C3)CC1 CHEMBL3698880 Ki 962.0 nM