Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1OC(=O)c1ccc(-c2ccccc2)cc1 CHEMBL339386 EC50 2.0 nM
O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](O)[C@@H]1O CHEMBL1160555 pIC50 3.548 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@H]2OC3(O[C@H]21)C([N+](=O)[O-])=CC(=[N+]([O-])[O-])C=C3[N+](=O)[O-] CHEMBL1163419 EC50 6.0 nM
O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cc(Cl)ccc1O CHEMBL536151 IC50 19.2 nM
O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccc(Cl)cc1O CHEMBL2338696 IC50 23.1 nM
O=C(Nc1cc(Cl)cc(Cl)c1)c1cc(Cl)ccc1O CHEMBL2179173 IC50 29.3 nM
O=C(Nc1cc([N+](=O)[O-])cc(C(F)(F)F)c1)c1cc(Cl)ccc1O CHEMBL4640175 IC50 31.6 nM
O=C(Nc1ccc(C(F)(F)F)cc1)c1cc(Cl)ccc1O CHEMBL2088014 IC50 38.3 nM
O=C(Nc1cc(F)cc(F)c1)c1cc(Cl)ccc1O CHEMBL2179174 IC50 50.5 nM
CSc1nc(N)c2ncn([C@@H]3O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]3O)c2n1 CHEMBL336208 EC50 54.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL14249 EC50 56.0 nM
O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cccc(Cl)c1O CHEMBL2338695 IC50 58.0 nM
O=C(Nc1cccc(C(=O)Nc2cc(C(=O)Nc3ccc(S(=O)(=O)[O-])c4cc(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c34)ccc2F)c1)Nc1cccc(C(=O)Nc2cc(C(=O)Nc3ccc(S(=O)(=O)[O-])c4cc(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c34)ccc2F)c1 CHEMBL413145 Log IC50 63.1 nM
O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cccc(F)c1O CHEMBL4644398 IC50 70.6 nM
O=C(Nc1cccc(Cl)c1)c1cc(Cl)ccc1O CHEMBL2088011 IC50 75.6 nM
O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1O CHEMBL461542 IC50 76.9 nM
O=C(Nc1cccc(C(F)(F)F)c1)c1cc(Cl)ccc1O CHEMBL589733 IC50 91.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@H]2OC3(O[C@H]21)C([N+](=O)[O-])=CC([N+](=O)[O-])C=C3[N+](=O)[O-] CHEMBL337395 IC50 120.0 nM
O=C(Nc1cccc([N+](=O)[O-])c1)c1cc(Cl)ccc1O CHEMBL2088009 IC50 172.0 nM
CC(C)(C)CN1CCC2(CC1)CN(c1ccccc1NC(=O)Nc1nc3ccc(Cl)nc3s1)c1c(O)ccc(Cl)c12 CHEMBL3263056 IC50 180.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]2O[C@@H](n3cnc4c(N)ncnc43)[C@H](O)[C@@H]2O)[C@@H](O)[C@H]1O CHEMBL339385 EC50 182.0 nM
O=C(Nc1ccc(Cl)cc1)c1cc(Cl)ccc1O CHEMBL2088012 IC50 199.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)CP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL132722 EC50 200.0 nM
O=C(Nc1cccc(C(=O)Nc2ccc(S(=O)(=O)[O-])c3cc(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c23)c1)Nc1cccc(C(=O)Nc2ccc(S(=O)(=O)[O-])c3cc(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c23)c1 CHEMBL216504 IC50 210.0 nM
O=C(Nc1cc([N+](=O)[O-])cc(C(F)(F)F)c1)c1cccc(Cl)c1O CHEMBL4637528 IC50 219.0 nM
O=C(Nc1cc(C(=O)Nc2ccc(S(=O)(=O)[O-])cc2S(=O)(=O)[O-])cc(C(=O)Nc2ccc(S(=O)(=O)[O-])cc2S(=O)(=O)[O-])c1)Nc1cc(C(=O)Nc2ccc(S(=O)(=O)[O-])cc2S(=O)(=O)[O-])cc(C(=O)Nc2ccc(S(=O)(=O)[O-])cc2S(=O)(=O)[O-])c1 CHEMBL1253351 IC50 236.0 nM
Cc1ccc(O)c(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1 CHEMBL2313115 IC50 236.0 nM
Cc1cc(C)cc(NC(=O)c2cc(Cl)ccc2O)c1 CHEMBL2178702 IC50 323.0 nM
O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1cc(Cl)ccc1O CHEMBL4648128 IC50 335.0 nM
O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccc2ccccc2c1O CHEMBL2338686 IC50 341.0 nM
O=S(=O)(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cc(Cl)ccc1O CHEMBL2313133 IC50 439.0 nM
O=C(N[C@H](Cc1cscn1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)C1CC1)c1nc2ccccc2[nH]1 CHEMBL190141 IC50 496.0 nM
N#Cc1cccc(NC(=O)c2cc(Cl)ccc2O)c1 CHEMBL2179168 IC50 522.0 nM
CC(C)(C)c1cccc(NC(=O)c2cc(Cl)ccc2O)c1 CHEMBL2179170 IC50 567.0 nM
OC1(c2ccccc2)c2ccccc2N(Cc2ccccc2)c2ccccc21 CHEMBL2180149 IC50 602.0 nM
Cc1cccc(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1O CHEMBL4639803 IC50 655.0 nM
COc1ccc(O)c(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1 CHEMBL2313119 IC50 755.0 nM
O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cccc([N+](=O)[O-])c1O CHEMBL3628655 IC50 869.0 nM
O=C(Nc1ccc(F)cc1)c1cc(Cl)ccc1O CHEMBL2312822 IC50 907.0 nM
COc1cc(NC(=O)c2cc(Cl)ccc2O)cc(OC)c1 CHEMBL4634436 IC50 915.0 nM