CC(C)C[C@H](N)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)O)[C@@H](C)O)C(C)C)C(C)C CHEMBL395493 IC50 0.0083 nM
O=C(Nc1cnc(Nc2ccc(Oc3cncc(F)c3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C1CCOCC1 CHEMBL3910178 IC50 0.8 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@H]2OC3(O[C@H]21)C([N+](=O)[O-])=CC(=[N+]([O-])[O-])C=C3[N+](=O)[O-] CHEMBL1163419 EC50 0.9 nM
Cc1ccc(Oc2ccc(Nc3ncc(NC(=O)C4CCOCC4)c(=O)n3Cc3ccc(Cl)cc3)cc2)cn1 CHEMBL3917952 IC50 1.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1C(N)=O)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679934 IC50 2.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1C(=O)NCCO)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679935 IC50 2.0 nM
CNC(=O)c1ccccc1C1c2c(n[nH]c2C(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679936 IC50 2.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1C(=O)N(C)C)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679937 IC50 2.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccsc2)nc1 CHEMBL3684651 IC50 2.0 nM
O=C(Nc1cnc(Nc2ccc(Oc3cc[nH]c(=O)c3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C1CCOCC1 CHEMBL3977217 IC50 2.0 nM
Cc1ccc(Oc2ccc(Nc3ncc(NC(=O)C(C)(C)O)c(=O)n3Cc3ccc(Cl)cc3)cc2)cn1 CHEMBL3985879 IC50 2.0 nM
COC(=O)c1cncc(Oc2ccc(Nc3ncc(NC(=O)C4CCOCC4)c(=O)n3Cc3ccc(Cl)cc3)cc2)c1 CHEMBL3891765 IC50 2.0 nM
O=C(O)c1cccc(Oc2ccc(Nc3ncc(NC(=O)C4CCOCC4)c(=O)n3Cc3ccc(Cl)cc3)cc2)c1 CHEMBL3910668 IC50 2.0 nM
Cc1ccc(-c2cc(C(=O)N[C@H](C)c3ccc(F)c[n+]3[O-])cc(-c3ncccc3F)c2)nc1 CHEMBL4227560 INH 2.0 nM
CC(C)(C)c1[nH]nc2c1C(c1ccccc1OCCO)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679947 IC50 3.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3684621 IC50 3.0 nM
CC(C)(C)c1[nH]nc2c1C(c1ccccc1OCc1nnn[nH]1)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3684586 IC50 3.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1OCc1nnn[nH]1)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3684587 IC50 3.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2cccs2)nc1 CHEMBL3684652 IC50 3.0 nM
COC(=O)[C@H](C)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL4109234 IC50 3.0 nM
COC(=O)[C@H](C)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL4109692 IC50 3.0 nM
CCc1nc2ccc(Nc3ncc(NC(=O)C4CCOCC4)c(=O)n3Cc3ccc(Cl)cc3)cc2s1 CHEMBL3944921 IC50 3.0 nM
Cc1ncc(Oc2ccc(Nc3ncc(NC(=O)C4CCOCC4)c(=O)n3Cc3ccc(Cl)cc3)cc2)cc1F CHEMBL3915726 IC50 3.0 nM
CCn1c(=O)cc(Nc2ccc(Oc3ccnc(C(=O)O)c3)cc2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3904878 IC50 3.0 nM
COC(=O)c1cccc(Oc2ccc(Nc3ncc(NC(=O)C4CCOCC4)c(=O)n3Cc3ccc(Cl)cc3)cc2)c1 CHEMBL3979986 IC50 3.0 nM
Cc1nc2ccc(Nc3ncc(NC(=O)C(C)(C)O)c(=O)n3Cc3ccc(Cl)cc3)cc2s1 CHEMBL3901780 IC50 3.0 nM
Cc1ccc(-c2cc(C(=O)N[C@H](C)c3nc(C)no3)cc(-c3ncccc3F)c2)nc1 CHEMBL4227351 INH 3.0 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(Oc3cccc(F)n3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5079957 IC50 3.0 nM
CCC(=O)N1CCOC(Cc2c(-c3c(C)cc(C(=O)NC)cc3C)nc3cc(C)ccn23)C1 CHEMBL5186232 IC50 3.0 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(Oc3ccc(F)cn3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5076078 IC50 3.1 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3N3CCOCC3)cc2)o1 CHEMBL3679752 IC50 4.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCC#N CHEMBL3669822 IC50 4.0 nM
CC(C)(C)c1[nH]nc2c1C(c1ccccc1OCCO)N(c1ccc(-c3cccs3)cc1)C2=O CHEMBL3679863 IC50 4.0 nM
CC(C)(C)c1[nH]nc2c1C(c1ccccc1OCC(=O)O)N(c1ccc(-c3cccs3)cc1)C2=O CHEMBL3679873 IC50 4.0 nM
CC(C)(C)c1[nH]nc2c1C(c1ccccc1OCC(=O)O)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679874 IC50 4.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1NS(C)(=O)=O)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679932 IC50 4.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1OCC#N)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3684553 IC50 4.0 nM
COCCOc1ccccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3684555 IC50 4.0 nM
CC(C)(C)c1[nH]nc2c1C(c1ccccc1OCC(N)=O)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3684581 IC50 4.0 nM
CC(C)(C)c1[nH]nc2c1C(c1ccccc1OCC#N)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3684585 IC50 4.0 nM
CCOC(=O)C1(Cn2c(=O)[nH]/c(=N\c3ccc(OC(C)C)c(Cl)c3)n(Cc3ccc(Cl)cc3)c2=O)CC1 CHEMBL3969451 IC50 4.0 nM
COC(=O)C(C)(C)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(C)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3908446 IC50 4.0 nM
COC(=O)[C@@H](C)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3954750 IC50 4.0 nM
CCOc1ccc(/N=c2\[nH]c(=O)n(CC(C)(C)C(=O)OC)c(=O)n2Cc2ccc(Cl)cc2)cc1C CHEMBL3924376 IC50 4.0 nM
CCOC(=O)CCCn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(C)c2)n(Cc2ccc(C)cc2)c1=O CHEMBL3967864 IC50 4.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(=O)C3CCOCC3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3971893 IC50 4.0 nM
Cc1nc2ccc(Nc3ncc(NC(=O)C4CCOCC4)c(=O)n3Cc3ccc(Cl)cc3)cc2s1 CHEMBL3889935 IC50 4.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(=O)C(C)(C)O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3969973 IC50 4.0 nM
O=C(O)c1cncc(Oc2ccc(Nc3ncc(NC(=O)C4CCOCC4)c(=O)n3Cc3ccc(Cl)cc3)cc2)c1 CHEMBL3983550 IC50 4.0 nM
O=C(Nc1cnc(Nc2ccc(Oc3cnc(Cl)c(F)c3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C1CCOCC1 CHEMBL3917090 IC50 4.0 nM
O=C(Cn1c(=O)c2ccc(C(F)F)nc2n2ncc(C3CC3)c12)Nc1ccc(F)cn1 CHEMBL5410018 IC50 4.0 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(Oc3ccccn3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5084939 IC50 4.2 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(Oc3cc(F)ccn3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5084068 IC50 4.9 nM
CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1N1CCOCC1 CHEMBL3674945 IC50 5.0 nM
CC(C)(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCC#N CHEMBL3669820 IC50 5.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCC1OCCO1 CHEMBL3679812 IC50 5.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCC(=N)NO CHEMBL3674748 IC50 5.0 nM
CC(C)(C)c1[nH]nc2c1C(c1cccnc1OCCO)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679890 IC50 5.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3684622 IC50 5.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1OC(CO)CO)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3684635 IC50 5.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1OCC(=O)NN)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679902 IC50 5.0 nM
CNC(=O)COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3684579 IC50 5.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCCOC3CCCCO3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3971710 IC50 5.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CC(=O)NCC(N)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3919611 IC50 5.0 nM
COC(=O)[C@@H](C)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3916125 IC50 5.0 nM
CCOC(=O)CCCn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(C)cc2)c1=O CHEMBL3952438 IC50 5.0 nM
COC(=O)C[C@@H](C)n1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL4111628 IC50 5.0 nM
COC(=O)[C@H](C)Cn1c(=O)[nH]/c(=N\c2ccc3oc(C)cc3c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL4110329 IC50 5.0 nM
CC(C)Oc1ccc(Nc2cc(=O)n(CC3COC(C)(C)OC3)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3949649 IC50 5.0 nM
Cc1ccc(-c2cc(C(=O)N[C@H](C)c3ccc(C(F)(F)F)[n+]([O-])c3)cc(-c3ncccc3F)c2)nc1 CHEMBL4228508 INH 5.0 nM
Cc1ccc(-c2cc(C(=O)N[C@H](C)c3ccc(C(F)(F)F)[n+]([O-])c3)cc(C(C)(C)O)c2)nc1 CHEMBL4227903 INH 5.0 nM
COc1ccc(OC)c(CCn2cnc3ccc(-c4ccc(NC(C)=O)cc4OC)cc3c2=O)c1 CHEMBL4456466 IC50 5.0 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(Oc3ccncc3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5083455 IC50 5.2 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(Oc3ccnc(F)c3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5084053 IC50 5.4 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(Oc3ccsn3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5073093 IC50 5.6 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(Oc3cncc(F)c3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5090841 IC50 5.6 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(C[C@@H](O)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL5082905 IC50 5.7 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(Oc3cnccn3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5069953 IC50 5.8 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1N1CCOCC1 CHEMBL3674946 IC50 6.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCC(CO)CO CHEMBL3674958 IC50 6.0 nM
COCCCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679755 IC50 6.0 nM
COCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)o2)cc1 CHEMBL3674897 IC50 6.0 nM
COCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669849 IC50 6.0 nM
COCCOc1ccccc1[C@@H]1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674750 IC50 6.0 nM
COCCOc1ncccc1[C@@H]1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674905 IC50 6.0 nM
COCCOc1ncccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679883 IC50 6.0 nM
COCCOc1ncccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3679886 IC50 6.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1OCCS(C)(=O)=O)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3684644 IC50 6.0 nM
CCOC(=O)C1(Cn2c(=O)[nH]/c(=N\c3ccc(OC(C)C)c(F)c3)n(Cc3ccc(Cl)cc3)c2=O)CC1 CHEMBL3924964 IC50 6.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CC(=O)NCC#N)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3930309 IC50 6.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CC(=O)NCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3945438 IC50 6.0 nM
COC(=O)[C@@H](C)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(F)c2)n(Cc2ccc(C)cc2)c1=O CHEMBL3960994 IC50 6.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCOC3CCCCO3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3986030 IC50 6.0 nM
CC(C)Oc1ccc(Nc2cc(=O)n(CC(C)(C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3985829 IC50 6.0 nM
CC(C)Oc1ccc(Nc2cc(=O)n(CC(CO)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3913269 IC50 6.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(=O)C3CCOCC3)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3960770 IC50 6.0 nM
CCn1c(=O)cc(Nc2ccc(Oc3cncc(C(=O)O)c3)cc2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3913868 IC50 6.0 nM
COc1ccc(OC)c(CCn2cnc3ccc(-c4ccc(NC(C)=O)nc4C)cc3c2=O)c1 CHEMBL4464155 IC50 6.0 nM
CC(C)c1ccc2c(=O)n(CC(=O)Nc3ccc(F)cn3)c3c(C4CC4)cnn3c2n1 CHEMBL5422168 IC50 6.0 nM
COc1cc(C(C)C)c(Oc2cnc(NC(CO)CO)nc2N)cc1I CHEMBL494161 IC50 6.3 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(Oc3nccs3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5086991 IC50 6.3 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3967323 IC50 6.7 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CC(CO)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3940500 IC50 6.7 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3965596 IC50 6.9 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCCCO CHEMBL3674933 IC50 7.0 nM
COCCOc1ccccc1[C@@H]1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 CHEMBL3674967 IC50 7.0 nM
COCCOc1ncccc1[C@@H]1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 CHEMBL3679738 IC50 7.0 nM
COCCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3639686 IC50 7.0 nM
COCc1ccccc1[C@@H]1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674871 IC50 7.0 nM
COCCOc1cc(F)ccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674878 IC50 7.0 nM
COCc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)o2)cc1 CHEMBL3674895 IC50 7.0 nM
COCCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)o2)cc1 CHEMBL3674896 IC50 7.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC(C)C)cc2)o1 CHEMBL3674906 IC50 7.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1OCC(N)=O)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679901 IC50 7.0 nM
CN(C)C(=O)COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3684578 IC50 7.0 nM
CC(C)(C)c1[nH]nc2c1C(c1ccccc1OCCNS(C)(=O)=O)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3684583 IC50 7.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(CO)CO)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3684662 IC50 7.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CC3(CO)CC3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3979713 IC50 7.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CC(=O)NC(CO)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3958850 IC50 7.0 nM
Cc1ccc(Cn2c(=O)n(CC(=O)NC(CO)CO)c(=O)[nH]/c2=N\c2ccc(OC(C)C)c(F)c2)cc1 CHEMBL3961702 IC50 7.0 nM
COC(=O)[C@H](C)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)cc2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL4110830 IC50 7.0 nM
Cc1ccc(Cn2c(=O)n(C[C@H](C)C(=O)O)c(=O)[nH]/c2=N\c2ccc(OC(C)C)c(Cl)c2)cc1 CHEMBL3943717 IC50 7.0 nM
CCOc1ccc(/N=c2\[nH]c(=O)n(C[C@H](C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3898831 IC50 7.0 nM
COC(=O)C[C@@H](C)n1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL4110237 IC50 7.0 nM
CCNC(=O)Nc1cnc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3951022 IC50 7.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(=O)NC3CCOCC3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3950429 IC50 7.0 nM
Cc1ccc(Oc2ccc(Nc3ncc(NC(=O)C(CO)CO)c(=O)n3Cc3ccc(Cl)cc3)cc2)cn1 CHEMBL3925124 IC50 7.0 nM
COc1ccc(OC)c(CCn2cnc3ccc(-c4ccc(N)nc4C)cc3c2=O)c1 CHEMBL4521422 IC50 7.0 nM
O=C(Cn1c(=O)c2ccc(C(F)(F)F)nc2n2ncc(C3CC3)c12)Nc1ccc(F)cn1 CHEMBL5413520 IC50 7.0 nM
O=C(Cn1c(=O)c2ccc(C3CC3)nc2n2ncc(C3CC3)c12)Nc1ccc(F)cn1 CHEMBL5425676 IC50 7.0 nM
O=C(Cn1c(=O)c2ccc(C(F)(F)F)nc2n2ncc(C(F)F)c12)Nc1ccc(F)cn1 CHEMBL5406794 IC50 7.0 nM
O=C(Cn1c(=O)c2sc(C3CC3)nc2n2ncc(C3CC3)c12)Nc1ccc(F)cn1 CHEMBL5409070 IC50 7.0 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(Oc3cccnn3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5091823 IC50 7.7 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(C[C@H](C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3930565 IC50 7.8 nM
COCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3674755 IC50 8.0 nM
COCc1ccccc1[C@@H]1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674779 IC50 8.0 nM
COCCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 CHEMBL3674787 IC50 8.0 nM
CC(C)Oc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674817 IC50 8.0 nM
CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCC(CO)CO CHEMBL3679764 IC50 8.0 nM
CC(C)(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCC(N)=O CHEMBL3669797 IC50 8.0 nM
CCOCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679805 IC50 8.0 nM
CSc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679818 IC50 8.0 nM
COc1ccccc1[C@@H]1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669843 IC50 8.0 nM
COC(=O)COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679871 IC50 8.0 nM
COCCOc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccco2)cc1 CHEMBL3679878 IC50 8.0 nM
COCCOc1ncccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccco2)cc1 CHEMBL3679888 IC50 8.0 nM
CC(C)(C)c1[nH]nc2c1C(c1ccccc1OCCO)N(c1ccc(-c3ccoc3)cc1)C2=O CHEMBL3684550 IC50 8.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2ccsc2)cn1 CHEMBL3684649 IC50 8.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CC(C)(C)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3908488 IC50 8.0 nM
CCOC(=O)CCn1c(=O)nc(Nc2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3899585 IC50 8.0 nM
COC(=O)C(C)(C)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3931340 IC50 8.0 nM
CNC(=O)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3905961 IC50 8.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(Cc3ccc(C(=O)O)cc3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3919713 IC50 8.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n([C@H](C)CC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL4110674 IC50 8.0 nM
Cc1nc2ccc(Nc3nc(=O)c(C(=O)NC4CCOCC4)cn3Cc3ccc(Cl)cc3)cc2s1 CHEMBL3936591 IC50 8.0 nM
Cc1ccc(-c2cc(C(=O)N[C@H](C)c3ccc(F)cn3)cc(-c3ncccc3F)c2)nc1 CHEMBL2324351 INH 8.0 nM
Cc1ccc(-c2cc(C(=O)N[C@H](C)c3ccc(C(F)(F)F)nc3)cc(-c3ncccc3F)c2)nc1 CHEMBL4229119 INH 8.0 nM
COc1ccccc1[C@@H]1C(C(=O)C(C)C)=C([O-])C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL4439812 IC50 8.0 nM
Cc1cnc(-c2cc(O[C@@H]3CCOC3)cc(C(=O)N[C@H](C)c3cnc(C(F)(F)F)nc3)c2)s1 CHEMBL5095224 IC50 8.0 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(Oc3cccnc3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5075206 IC50 8.6 nM
COCCOc1cc(F)ccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674879 IC50 9.0 nM
COC(=O)COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3679872 IC50 9.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1NC(N)=O)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679931 IC50 9.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CC(C)(CO)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3937738 IC50 9.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCC#N)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3896038 IC50 9.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(C[C@H](C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3899869 IC50 9.0 nM
CCOC(=O)CCCn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3898555 IC50 9.0 nM
CC(C)Oc1ccc(Nc2cc(=O)n(C[C@H](C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3979169 IC50 9.0 nM
Cc1ccc(Oc2ccc(Nc3ncc(NC(=O)C4COC(C)(C)OC4)c(=O)n3Cc3ccc(Cl)cc3)cc2)cn1 CHEMBL3919670 IC50 9.0 nM
CCn1c(=O)cc(Nc2ccc(Oc3ccnc(C(=O)OC)c3)cc2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3936398 IC50 9.0 nM
Cc1nc2ccc(Nc3ncc(NC(=O)OC(C)(C)C)c(=O)n3Cc3ccc(Cl)cc3)cc2s1 CHEMBL3927447 IC50 9.0 nM
Cc1nc2ccc(Nc3cc(=O)n(CCOC4CCCCO4)c(=O)n3Cc3ccc(Cl)cc3)cc2s1 CHEMBL3905050 IC50 9.0 nM
COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccc(-c4cc(C)no4)cc3)C2C2CCCCC2)cc1 CHEMBL4126267 IC50 9.0 nM
Cc1ccc(Cn2c(=O)n(CC(C)(C)C(=O)O)c(=O)[nH]/c2=N\c2ccc(OC(C)C)c(Cl)c2)cc1 CHEMBL3970038 IC50 9.8 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(Oc3ncccn3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5094828 IC50 9.9 nM
COCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674773 IC50 10.0 nM
COCc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674776 IC50 10.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3cccnc3OC(C)C)cc2)o1 CHEMBL3679745 IC50 10.0 nM
CC(C)OCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679803 IC50 10.0 nM
CC(C)(C)c1[nH]nc2c1C(c1cccnc1OCCO)N(c1ccc(-c3cccs3)cc1)C2=O CHEMBL3679893 IC50 10.0 nM
COCCOc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3684551 IC50 10.0 nM
CC(=O)NCCOc1ccccc1C1c2c(n[nH]c2C(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3684588 IC50 10.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCOC3CCCCO3)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3898781 IC50 10.0 nM
COC(=O)C(C)(C)Cn1c(=O)[nH]/c(=N\c2ccc3oc(C)cc3c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3975676 IC50 10.0 nM
COC(=O)[C@@H](C)Cn1c(=O)nc(Nc2ccc(OC(C)C)c(C)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3944396 IC50 10.0 nM
CCOc1ccc(Nc2nc(=O)n(C[C@H](C)C(=O)OC)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3960614 IC50 10.0 nM
COC(=O)C(C)(C)Cn1c(=O)cc(Nc2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3903559 IC50 10.0 nM
CC(=O)N1CCC(C(=O)Nc2cnc(Nc3ccc(OC(C)C)c(F)c3)n(Cc3ccc(Cl)cc3)c2=O)CC1 CHEMBL3902839 IC50 10.0 nM
Cc1nc2ccc(Nc3ncc(NC(=O)C(CO)CO)c(=O)n3Cc3ccc(Cl)cc3)cc2s1 CHEMBL3929727 IC50 10.0 nM
CCOC(=O)c1ccc(N2C(=O)C(O)=C(C(=O)c3ccc(OC)cc3)C2C2CCCCC2)cc1 CHEMBL4129184 IC50 10.0 nM
Cc1ccc(-c2cc(C(=O)N[C@@H](C)c3nnc[nH]3)cc(-c3ncccc3F)c2)nc1 CHEMBL4228231 INH 10.0 nM
CCC(CC)C1C(C(=O)c2ccc(OC)cc2)=C(O)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL4439493 IC50 10.0 nM
COc1ccc(OC)c(CCn2cnc3sc4c(c3c2=O)CCN(C(=O)C(C)(C)C)C4)c1 CHEMBL4476395 IC50 10.0 nM
COc1ncc([C@@H](C)Nc2ncnc3c2CN(c2ccc(C)cc2C#N)CC3)cn1 CHEMBL3732768 IC50 10.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(C[C@H](O)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL5085884 IC50 10.4 nM
COCCOc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669772 IC50 11.0 nM
COCc1ccccc1[C@@H]1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3674904 IC50 11.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1OCC(=O)O)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679898 IC50 11.0 nM
CNC(=O)COc1ccccc1C1c2c(n[nH]c2C(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679900 IC50 11.0 nM
COCCOc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3684544 IC50 11.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3684618 IC50 11.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679923 IC50 11.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1OCC[S+](C)[O-])N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679924 IC50 11.0 nM
COc1ccccc1C1c2c(C(C)(C)C(=O)N(C)C)n[nH]c2C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3684584 IC50 11.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1OCC(=N)NO)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3684595 IC50 11.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2cccs2)cn1 CHEMBL3684660 IC50 11.0 nM
CC(=O)NCCCn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3957828 IC50 11.0 nM
CCOc1ccc(/N=c2\[nH]c(=O)n(CC(C)(C)C(=O)OC)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3961643 IC50 11.0 nM
COC(=O)C(C)(C)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(Cl)c2)n(CC2CCCCC2)c1=O CHEMBL3974656 IC50 11.0 nM
CC(C)Oc1ccc(NC2=CC(O)N(CC(=O)NC(CO)CO)C(=O)N2Cc2ccc(Cl)cc2)cc1F CHEMBL3961792 IC50 11.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(=O)C3CCOCC3)c(=O)n2Cc2ccc(Cl)cc2)cc1 CHEMBL3938800 IC50 11.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(=O)c3cc[nH]c(=O)c3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3892779 IC50 11.0 nM
CSc1ccc(Cn2c(Nc3ccc4nc(C)sc4c3)ncc(NC(=O)C3CCOCC3)c2=O)cc1 CHEMBL3963866 IC50 11.0 nM
COCCOc1ccccc1C1C(C(=O)C(C)(C)C)=C(O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL4592312 IC50 11.0 nM
CNC(=O)c1ccc(C(=O)C2=C(O)C(=O)N(c3ccc(-c4ccon4)cc3)C2C2CCCCC2)cc1 CHEMBL4466162 IC50 11.0 nM
CCNC(=O)c1ccc(C(=O)C2C(=O)C(=O)N(c3ccc(-c4ccon4)cc3)C2C(CC)CC)cc1 CHEMBL3669697 IC50 12.0 nM
COc1ccc(C(=O)C2C(=O)C(=O)N(c3ccc(-c4ccco4)cc3)C2C2CCCCC2)cc1 CHEMBL3639685 IC50 12.0 nM
COc1ccc(C(=O)C2C(=O)C(=O)N(c3ccc(-c4ccoc4)cc3)C2C2CCCCC2)cc1 CHEMBL3669722 IC50 12.0 nM
COCCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3674754 IC50 12.0 nM
COC(=O)COc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3669762 IC50 12.0 nM
COC(=O)COc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669763 IC50 12.0 nM
CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OC(C)C CHEMBL3674812 IC50 12.0 nM
Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OCC3OCCO3)cc2)cs1 CHEMBL3679766 IC50 12.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCc1nnn[nH]1 CHEMBL3669853 IC50 12.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3cccs3)cc2)C1c1ccccc1OCCO CHEMBL3674751 IC50 12.0 nM
COC(=O)Nc1ccccc1C1c2c(n[nH]c2C(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679939 IC50 12.0 nM
COCCOc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3684543 IC50 12.0 nM
C[S+]([O-])CCOc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679920 IC50 12.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1OCC(C)(C)O)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3684594 IC50 12.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CC(CO)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3929980 IC50 12.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCN3CCOCC3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3957484 IC50 12.0 nM
CCOC(=O)CCn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3896534 IC50 12.0 nM
COC(=O)C(C)(C)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(F)c2)n(Cc2ccc(C)cc2)c1=O CHEMBL3955205 IC50 12.0 nM
COC(=O)CCn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(F)c2)n(Cc2ccc(C)cc2)c1=O CHEMBL3901615 IC50 12.0 nM
CCOc1ccc(/N=c2\[nH]c(=O)n(C[C@@H](C)C(=O)OC)c(=O)n2Cc2ccc(Cl)cc2)cc1 CHEMBL4111411 IC50 12.0 nM
CCOc1ccc(/N=c2\[nH]c(=O)n(C[C@@H](C)C(=O)OC)c(=O)n2Cc2ccc(Cl)cc2)cc1C CHEMBL4106887 IC50 12.0 nM
Cc1ccc(Cn2c(=O)n(CCCC(=O)O)c(=O)[nH]/c2=N\c2ccc(OC(C)C)c(Cl)c2)cc1 CHEMBL3976397 IC50 12.0 nM
COC(=O)[C@@H](C)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(Cl)c2)n(CC2CCCCC2)c1=O CHEMBL3898263 IC50 12.0 nM
CC(C)(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCCO CHEMBL3669739 IC50 13.0 nM
CCOc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674944 IC50 13.0 nM
CC(C)COc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674952 IC50 13.0 nM
COCCOc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3669771 IC50 13.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCCO CHEMBL3669805 IC50 13.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCC[S+](C)[O-] CHEMBL3669810 IC50 13.0 nM
COCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669825 IC50 13.0 nM
CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCCCO CHEMBL3674881 IC50 13.0 nM
COCCCOc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679824 IC50 13.0 nM
COCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3669851 IC50 13.0 nM
CC(C)(C)c1[nH]nc2c1C(c1ccccc1OCCO)N(c1ccc(-c3ccco3)cc1)C2=O CHEMBL3679948 IC50 13.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccsc2)cn1 CHEMBL3684647 IC50 13.0 nM
COCCOc1ncccc1C1c2c(n[nH]c2C(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3684671 IC50 13.0 nM
CCCn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3984127 IC50 13.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CCCC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3954802 IC50 13.0 nM
COC(=O)[C@@H](C)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(C)c2)n(CC2CCCCC2)c1=O CHEMBL3934428 IC50 13.0 nM
Cc1cc(Nc2ncc(NC(=O)C3CCOCC3)c(=O)n2Cc2ccc(Cl)cc2)ccc1OC(C)C CHEMBL3933311 IC50 13.0 nM
CC(C)(C)C(=O)C1=C(O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCCO CHEMBL4466252 IC50 13.0 nM
CC(C)C(=O)C1=C(O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCCO CHEMBL4537290 IC50 13.0 nM
CC(C)C(=O)C1=C(O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCC[S+](C)[O-] CHEMBL4437131 IC50 13.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3974083 IC50 13.0 nM
CCC(CC)C1C(C(=O)c2ccc(C(=O)NCCO)cc2)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL3669701 IC50 14.0 nM
COc1ccc(C(=O)C2C(=O)C(=O)N(c3nc4ccc(OC)cc4s3)C2C2CCCCC2)cc1 CHEMBL3669702 IC50 14.0 nM
COCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 CHEMBL3674788 IC50 14.0 nM
COCCOc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 CHEMBL3674791 IC50 14.0 nM
COCc1ccccc1[C@@H]1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)c2)cc1 CHEMBL3674957 IC50 14.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCC(N)=O CHEMBL3669828 IC50 14.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1cccnc1OCC(N)=O CHEMBL3669838 IC50 14.0 nM
COCCOc1ccccc1[C@@H]1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3669844 IC50 14.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3OC(C)C)cc2)o1 CHEMBL3674908 IC50 14.0 nM
COC(=O)COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL3679879 IC50 14.0 nM
COCCOc1ncccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3679889 IC50 14.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3684623 IC50 14.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3961985 IC50 14.0 nM
COC(=O)C(C)n1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3961471 IC50 14.0 nM
COC(=O)CCCn1c(=O)cc(Nc2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3950132 IC50 14.0 nM
CC(C)Oc1ccc(NC2=CC(O)N(CC(=O)NCCO)C(=O)N2Cc2ccc(Cl)cc2)cc1F CHEMBL3896129 IC50 14.0 nM
CC(=O)OC(C)(C)C(=O)Nc1cnc(Nc2ccc(Oc3ccc(C)nc3)cc2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3980790 IC50 14.0 nM
Cc1ccc(-c2cc(C(=O)N[C@H](C)c3ccc(C(F)(F)F)nc3)cc(C(C)(C)O)c2)nc1 CHEMBL4227222 INH 14.0 nM
C[C@@H](NC(=O)c1cc(-c2ccc(Cl)cn2)cc(C(C)(C)O)c1)c1ccc(C(F)(F)F)[n+]([O-])c1 CHEMBL4229237 INH 14.0 nM
CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)O)[C@@H](C)O)C(C)C CHEMBL238310 IC50 14.3 nM
COCCOc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3639736 IC50 15.0 nM
COCCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674771 IC50 15.0 nM
COc1ccc(C(=O)C2C(=O)C(=O)N(c3nc4ccc(OC)cc4s3)C2c2ccccc2OCCO)cc1 CHEMBL3669774 IC50 15.0 nM
CN(C)CCOc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669783 IC50 15.0 nM
COCCOc1ncccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3669795 IC50 15.0 nM
COCc1ccccc1[C@@H]1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 CHEMBL3674903 IC50 15.0 nM
COCCOc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2noc(C)n2)cc1 CHEMBL3679876 IC50 15.0 nM
CC(C)(C)c1[nH]nc2c1C(c1ccccc1OCC#N)N(c1ccc(-c3ccon3)cc1)C2=O CHEMBL3679951 IC50 15.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2ccco2)cc1 CHEMBL3684619 IC50 15.0 nM
Cc1ccc(N2CCc3ncnc(N[C@H](C)c4ccc(C(F)(F)F)nc4)c3C2)nc1 CHEMBL3643334 IC50 15.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCO)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3923313 IC50 15.0 nM
COC(=O)C(C)(C)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3928506 IC50 15.0 nM
CCOC(=O)CCCn1c(=O)[nH]/c(=N\c2ccc3oc(C)cc3c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3919280 IC50 15.0 nM
Cc1ccc(Cn2c(=O)n(C[C@H](C)C(=O)O)c(=O)[nH]/c2=N\c2ccc(OC(C)C)c(F)c2)cc1 CHEMBL3981230 IC50 15.0 nM
CCCC(=O)Nc1cnc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3904328 IC50 15.0 nM
CN(C)CCOc1ccccc1C1C(C(=O)C(C)(C)C)=C(O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL4572081 IC50 15.0 nM
COc1ccc(OC)c(CCn2cnc3sc4c(c3c2=O)CCN(C(=O)C2CC2)C4)c1 CHEMBL4544380 IC50 15.0 nM
CCC(C)(C)C(=O)N1CCc2c(sc3ncn(CCc4cc(OC)cc(OC)c4)c(=O)c23)C1 CHEMBL4542098 IC50 15.0 nM
COc1cc(CCn2cnc3sc4c(c3c2=O)CCN(C(=O)C(C)(F)F)C4)cc(OC)c1 CHEMBL4439566 IC50 15.0 nM
COc1cc(CCn2cnc3sc4c(c3c2=O)CCN(C(=O)C(F)(F)F)C4)cc(OC)c1 CHEMBL4587231 IC50 15.0 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(OC3CCC3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5071169 IC50 15.2 nM
COc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669741 IC50 16.0 nM
COCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)c2)cc1 CHEMBL3674786 IC50 16.0 nM
COc1ccccc1[C@@H]1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674800 IC50 16.0 nM
CC(C)(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3cccs3)cc2)C1c1ccccc1OCCO CHEMBL3669743 IC50 16.0 nM
COCCOc1ncccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669785 IC50 16.0 nM
C[S+]([O-])CCOc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669791 IC50 16.0 nM
COc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669804 IC50 16.0 nM
COCCOc1cc(F)ccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3674883 IC50 16.0 nM
CC(C)c1[nH]nc2c1C(c1cccnc1OCCO)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679896 IC50 16.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2cc[nH]c2)cc1 CHEMBL3684631 IC50 16.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1OCCN(C)C)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679922 IC50 16.0 nM
C=CCn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3976104 IC50 16.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CC3(C(=O)O)CC3)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3929347 IC50 16.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(Cc3cccc(C(=O)O)c3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3944080 IC50 16.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(C[C@@H](C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL4109356 IC50 16.0 nM
Cc1cc(/N=c2\[nH]c(=O)n(C[C@H](C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)ccc1OC(C)C CHEMBL3894785 IC50 16.0 nM
COC(=O)[C@@H](C)Cn1c(=O)cc(Nc2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3935762 IC50 16.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(=O)N3CCOCC3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3936334 IC50 16.0 nM
CC(=O)N1CCC(C(=O)Nc2cnc(Nc3ccc4nc(C)sc4c3)n(Cc3ccc(Cl)cc3)c2=O)CC1 CHEMBL3909816 IC50 16.0 nM
CC(C)(C)C(=O)C1=C(O)C(=O)N(c2ccc(-c3cccs3)cc2)C1c1ccccc1OCCO CHEMBL4465467 IC50 16.0 nM
COc1ccccc1C1C(C(=O)C(C)(C)C)=C(O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL4457637 IC50 16.0 nM
C[S+]([O-])CCOc1ccccc1C1C(C(=O)C(C)(C)C)=C(O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL4459391 IC50 16.0 nM
COc1ccccc1C1C(C(=O)C(C)C)=C(O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL4454941 IC50 16.0 nM
Cc1ccc(Cn2c(Nc3ccc(OC(C)C)c(Cl)c3)nc(=O)n(CCC(=O)O)c2=O)cc1 CHEMBL4748113 IC50 16.1 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(Oc3ccon3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5074869 IC50 16.6 nM
Nc1ccc(CCSc2nc(N)c3ncn([C@@H]4O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]4O)c3n2)cc1 CHEMBL337062 EC50 17.0 nM
COCCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674775 IC50 17.0 nM
COCCCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679756 IC50 17.0 nM
Cc1nc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC3CCCC3)cc2)no1 CHEMBL3679769 IC50 17.0 nM
CNC(=O)COc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669793 IC50 17.0 nM
CC(C)(C)c1[nH]nc2c1C(c1ccccc1OCCO)N(c1ccc(-c3nccs3)cc1)C2=O CHEMBL3679865 IC50 17.0 nM
CC(C)(C)c1[nH]nc2c1C(c1cccnc1OCCO)N(c1ccc(-c3ccco3)cc1)C2=O CHEMBL3679894 IC50 17.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3684611 IC50 17.0 nM
COc1cc(N2C(=O)c3n[nH]c(C(C)C)c3C2c2ccccc2OC)ccc1-c1ccsc1 CHEMBL3684634 IC50 17.0 nM
CCOC(=O)c1ccc(N2C(=O)c3n[nH]c(C(C)(C)C)c3C2c2ccccc2OC)cc1 CHEMBL3679906 IC50 17.0 nM
Cc1ccc(N2CCc3ncnc(N[C@H](C)c4cnc(C)nc4)c3C2)nc1 CHEMBL3643348 IC50 17.0 nM
COC(=O)c1ccc(Cn2c(=O)[nH]/c(=N\c3ccc(OC(C)C)c(F)c3)n(Cc3ccc(Cl)cc3)c2=O)cc1 CHEMBL3891664 IC50 17.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(=O)C(CO)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3922706 IC50 17.0 nM
Cc1ccc(-c2cc(C(=O)N[C@@H](C)c3nc(C)no3)cc(-c3ncccc3F)c2)nc1 CHEMBL4228939 INH 17.0 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(OCC3CC3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5074942 IC50 17.1 nM
COCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccco2)cc1 CHEMBL3674757 IC50 18.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OC(F)F CHEMBL3674819 IC50 18.0 nM
COc1cc(F)ccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674843 IC50 18.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1cccnc1N1CCOCC1 CHEMBL3679789 IC50 18.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1cccnc1OCCCO CHEMBL3679823 IC50 18.0 nM
CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccoc3)cc2)C1c1ccccc1OC(C)C CHEMBL3674916 IC50 18.0 nM
CN(C)CCOc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679882 IC50 18.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1CN(C)C)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679928 IC50 18.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2cccs2)cn1 CHEMBL3684653 IC50 18.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CC(=O)NCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3984797 IC50 18.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3946979 IC50 18.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CCC(=O)NCC#N)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3914909 IC50 18.0 nM
COC(=O)[C@@H](C)Cn1c(=O)[nH]/c(=N\c2ccc3oc(C)cc3c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3953691 IC50 18.0 nM
COC(=O)[C@H](C)NC(=O)c1cnc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3964128 IC50 18.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@H]2OC3(O[C@H]21)C([N+](=O)[O-])=CC([N+](=O)[O-])C=C3[N+](=O)[O-] CHEMBL337395 IC50 18.0 nM
COCCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)c2)cc1 CHEMBL3674785 IC50 19.0 nM
Cc1nc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OCC(C)C)cc2)no1 CHEMBL3639738 IC50 19.0 nM
COCCCOc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)o2)cc1 CHEMBL3679737 IC50 19.0 nM
CC(C)(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1cccnc1OCCO CHEMBL3669809 IC50 19.0 nM
COCCOc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669812 IC50 19.0 nM
COCCOc1cc(F)ccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3674882 IC50 19.0 nM
CNC(=O)COc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669837 IC50 19.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3OCCO)cc2)o1 CHEMBL3674899 IC50 19.0 nM
CSc1ccc(N2C(=O)c3n[nH]c(C(C)(C)C)c3C2c2ccccc2OCCO)cc1 CHEMBL3679864 IC50 19.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)C)C(=O)N1c1ccc(-c2ccsc2)c(F)c1 CHEMBL3684637 IC50 19.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2csc(C)c2)cc1 CHEMBL3684668 IC50 19.0 nM
Cc1ccc(N2CCc3ncnc(N[C@H](C)c4ccc(F)cc4)c3C2)nc1 CHEMBL3643333 IC50 19.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CC(F)(F)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3980535 IC50 19.0 nM
COC(=O)CNC(=O)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3924775 IC50 19.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CCC(C)(C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3916161 IC50 19.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(C[C@H](C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1 CHEMBL3893433 IC50 19.0 nM
COC(=O)C(C)(C)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(Cl)c2)n(CC2CCCCCC2)c1=O CHEMBL3966153 IC50 19.0 nM
COC(=O)C[C@@H](C)n1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(C)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL4109116 IC50 19.0 nM
CC(C)Oc1ccc(Nc2cc(=O)n(CC(C)(C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3984712 IC50 19.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(=O)C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3901112 IC50 19.0 nM
COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccc(-c4noc(C)n4)cc3)C2C2CCCCC2)cc1 CHEMBL4129491 IC50 19.0 nM
COc1ccc(OC)c(CCN2CCc3ccc(-c4ccccc4S(N)(=O)=O)cc3C2=O)c1 CHEMBL4468475 IC50 19.0 nM
COCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 CHEMBL3674823 IC50 20.0 nM
COCCOc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)o2)cc1 CHEMBL3674872 IC50 20.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccoc2)nc1 CHEMBL3684650 IC50 20.0 nM
CCOc1ccc(/N=c2\[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3926397 IC50 20.0 nM
CCOC(=O)CCCn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(C)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3913314 IC50 20.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(=O)OC(C)(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3898131 IC50 20.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(=O)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3936860 IC50 20.0 nM
CCOC(=O)c1ccc(N2C(=O)C(O)=C(C(=O)c3ccc(OC)cc3)C2c2ccc(F)cc2)cc1 CHEMBL4128213 IC50 20.0 nM
CCOC(=O)c1ccc(N2C(=O)C(O)=C(C(=O)c3ccc(OC)cc3)C2c2ccccc2)cc1 CHEMBL4130242 IC50 20.0 nM
Cc1ccc(-c2cc(C(=O)N[C@H](C)c3ccc(C(F)(F)F)[n+]([O-])c3)cc(C(C)(C)O)c2)cc1 CHEMBL4228395 INH 20.0 nM
COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1I CHEMBL526307 IC50 20.0 nM
COc1ccc(OC)c(CCn2cnc3sc4c(c3c2=O)CCN(S(=O)(=O)N(C)C)C4)c1 CHEMBL4458821 IC50 20.0 nM
COc1cc(CCn2cnc3sc4c(c3c2=O)CCN(S(=O)(=O)C(C)C)C4)cc(OC)c1 CHEMBL4448484 IC50 20.0 nM
COc1ccc(OC)c(CCn2cnc3ccc(-c4ccc(N)cc4OC)cc3c2=O)c1 CHEMBL4474615 IC50 20.0 nM
CC(=O)N1CCN(c2nc(NC(C)(C)Cc3ccc(Cl)cc3)c3c(n2)C(=O)N(C(C)C)C3)CC1 CHEMBL2011112 IC50 20.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3959782 IC50 20.0 nM
CC(=O)N1CCN(c2nc(N[C@H](C)c3cnc4ccccc4c3)c3c(n2)C(=O)N(C(C)C)C3)CC1 CHEMBL2324342 IC50 21.0 nM
COc1ccc(C(=O)C2C(=O)C(=O)N(c3ccc(-c4nc(C)no4)cc3)C2C2CCCCC2)cc1 CHEMBL3669709 IC50 21.0 nM
COCCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 CHEMBL3674822 IC50 21.0 nM
COCCOc1ncccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)o2)cc1 CHEMBL3674875 IC50 21.0 nM
CC(C)Oc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL3679870 IC50 21.0 nM
COc1ncccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679952 IC50 21.0 nM
COc1cccc([C@@H](C)Nc2ncnc3c2CN(c2ccc(C)cn2)CC3)c1 CHEMBL3643332 IC50 21.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CC3CCOCC3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3956259 IC50 21.0 nM
COc1ccc(Cn2c(=O)nc(Nc3ccc(OC(C)C)c(F)c3)n(Cc3ccc(Cl)cc3)c2=O)cc1 CHEMBL3971061 IC50 21.0 nM
COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccc(-c4nc(C)no4)cc3)C2C2CCCCC2)cc1 CHEMBL4128106 IC50 21.0 nM
Cc1ccc(-c2cc(C(=O)N[C@H](C)c3ccc(F)cn3)cc(C3=NO[C@H](c4ccccn4)C3)c2)nc1 CHEMBL4227228 INH 21.0 nM
C[C@@H](NC(=O)c1cc(-c2ccc(Cl)cc2)cc(C(C)(C)O)c1)c1ccc(C(F)(F)F)[n+]([O-])c1 CHEMBL4227558 INH 21.0 nM
COc1ccc(OC)c(CCn2cnc3sc4c(c3c2=O)CC[C@H](C(=O)N(C)C)C4)c1 CHEMBL4568965 IC50 21.0 nM
CCCCc1n[nH]c2c1C(c1ccccc1OC)N(c1ccc(-c3ccon3)cc1)C2=O CHEMBL4744004 IC50 21.0 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(Oc3ccccc3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5081850 IC50 21.8 nM
CC(=O)N1CCN(c2nc3c(c(N(C)Cc4cc5ccccc5cn4)n2)CN(C(C)C)C3=O)CC1 CHEMBL2011127 IC50 22.0 nM
CNC(=O)COc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669827 IC50 22.0 nM
COc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3669850 IC50 22.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC(C)C)cc2)s1 CHEMBL3674910 IC50 22.0 nM
COCCOc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL3679869 IC50 22.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2nccs2)cc1 CHEMBL3684562 IC50 22.0 nM
COC(=O)[C@@H](C)Cn1c(=O)nc(Nc2ccc(OC(C)C)cc2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3939006 IC50 22.0 nM
CC(C)COc1ccc(/N=c2\[nH]c(=O)n(C[C@H](C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1 CHEMBL5076689 IC50 22.0 nM
COCCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccco2)cc1 CHEMBL3674758 IC50 23.0 nM
Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OCCO)cc2)cs1 CHEMBL3674780 IC50 23.0 nM
COc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3669742 IC50 23.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCCN(C)C CHEMBL3669803 IC50 23.0 nM
COCCOc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(SC)cc1 CHEMBL3679877 IC50 23.0 nM
COc1ncccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3684625 IC50 23.0 nM
CC(=O)Nc1ccccc1C1c2c(n[nH]c2C(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679929 IC50 23.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(C[C@H](C)C(=O)O)c(=O)n2CC2CCCCC2)cc1Cl CHEMBL3975627 IC50 23.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(=O)C3COC(C)(C)OC3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3890206 IC50 23.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(=O)C(C)(C)C#N)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3978632 IC50 23.0 nM
CC(=O)N1CCN(c2nc(NCc3cnc4ccccc4c3)c3c(n2)C(=O)N(C(C)C)C3)CC1 CHEMBL2011125 IC50 24.0 nM
CC(=O)N1CCN(c2nc(NCc3cc4ccccc4cn3)c3c(n2)C(=O)N(C(C)C)C3)CC1 CHEMBL2011126 IC50 24.0 nM
COCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3674759 IC50 24.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OCCO)cc2)s1 CHEMBL3674782 IC50 24.0 nM
CC(C)(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3cccs3)cc2)C1c1cccnc1OCCO CHEMBL3669814 IC50 24.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC(F)(F)F)cc2)o1 CHEMBL3674874 IC50 24.0 nM
COc1ncccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3679953 IC50 24.0 nM
COc1ccccc1C1c2c(n[nH]c2C2CC2)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679927 IC50 24.0 nM
COc1ncccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccsc2)nc1 CHEMBL3684663 IC50 24.0 nM
Cc1ccc(N2CCc3ncnc(N[C@H](CCO)c4ccc(C(F)(F)F)nc4)c3C2)nc1 CHEMBL3643347 IC50 24.0 nM
CCOC(=O)c1ccccc1Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3942980 IC50 24.0 nM
COC(=O)C(C)(C)Cn1c(=O)[nH]/c(=N\c2cccc(C(F)(F)F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3903322 IC50 24.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n([C@@H](C)CC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3935918 IC50 24.0 nM
Cc1cc(Nc2cc(=O)n(C[C@H](C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)ccc1OC(C)C CHEMBL3923901 IC50 24.0 nM
COCCC(=O)Nc1cnc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3961137 IC50 24.0 nM
COC(=O)CCCn1c(=O)cc(Nc2ccc3nc(C)sc3c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3985309 IC50 24.0 nM
COCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 CHEMBL3674790 IC50 25.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC(F)F)cc2)o1 CHEMBL3674873 IC50 25.0 nM
COc1ncccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2cccs2)nc1 CHEMBL3684665 IC50 25.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(Cc3ccccn3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3900981 IC50 25.0 nM
CC(=O)OC(C)(C)C(=O)Nc1cnc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3926910 IC50 25.0 nM
COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccc(-c4ccon4)cc3)C2C2CCCCC2)cc1 CHEMBL4127637 IC50 25.0 nM
COc1ccc(OC)c(CCn2cnc3sc4c(c3c2=O)CCN(C(=O)C(C)C)C4)c1 CHEMBL4449004 IC50 25.0 nM
COc1ccccc1C1c2c(C(C)(C)C)n[nH]c2C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL4765176 IC50 25.0 nM
COc1ccccc1C1c2c(C(C)(C)C)n[nH]c2C(=O)N1c1ccc(-c2nccs2)cc1 CHEMBL4799974 IC50 25.0 nM
CNC(=O)c1cc(F)c(-c2nc3cc(C)ccn3c2C[C@@H]2CCCN(C(=O)OC)C2)c(F)c1 CHEMBL5207245 IC50 25.0 nM
COc1ccc(F)cc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674954 IC50 26.0 nM
CC(C)Oc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(N2CCCC2)cc1 CHEMBL3674961 IC50 26.0 nM
COCCOc1ncccc1C1C(C(=O)C2CCCC2)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679783 IC50 26.0 nM
CC(C)c1[nH]nc2c1C(c1cccnc1OCC(N)=O)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679904 IC50 26.0 nM
Cc1cc(/N=c2\[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)ccc1OC(C)C CHEMBL3936380 IC50 26.0 nM
COc1ccccc1C1c2c(C(C)(C)C)n[nH]c2C(=O)N1c1ccc(-c2noc(C)n2)cc1 CHEMBL4745598 IC50 26.0 nM
CCCC(CCC)C1C(C(=O)c2ccc(CO)cc2)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL3669699 IC50 27.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1C#N CHEMBL3674769 IC50 27.0 nM
COc1cc(F)ccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674844 IC50 27.0 nM
CC(C)(C)c1[nH]nc2c1C(c1cccnc1OCCO)N(c1ccc(-c3ccoc3)cc1)C2=O CHEMBL3679892 IC50 27.0 nM
CCOc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL3679945 IC50 27.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 CHEMBL3684669 IC50 27.0 nM
COc1ccc([C@@H](CO)Nc2ncnc3c2CN(c2ccc(C)cn2)CC3)cn1 CHEMBL3643344 IC50 27.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCN3CCCCC3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3982803 IC50 27.0 nM
CNC(=O)CCn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3969702 IC50 27.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CCC(C)(C)C(=O)OCc3ccccc3)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3891416 IC50 27.0 nM
CCOc1ccc(/N=c2\[nH]c(=O)n(C[C@@H](C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL4112026 IC50 27.0 nM
Cc1cc2cc(/N=c3\[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n3Cc3ccc(Cl)cc3)ccc2o1 CHEMBL3893053 IC50 27.0 nM
Cc1cc2cc(/N=c3\[nH]c(=O)n(C[C@H](C)C(=O)O)c(=O)n3Cc3ccc(Cl)cc3)ccc2o1 CHEMBL3971702 IC50 27.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n([C@H](C)CC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL4113708 IC50 27.0 nM
COCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)c2)cc1 CHEMBL3674789 IC50 28.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccon3)cc2)C1c1ccccc1OCC1CCOCC1 CHEMBL3679848 IC50 28.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccco2)cc1 CHEMBL3684610 IC50 28.0 nM
Cc1ccc(N2CCc3ncnc(N[C@H](CCO)c4ccc(C)nc4)c3C2)nc1 CHEMBL3643345 IC50 28.0 nM
COC(=O)C(C)(C)Cn1c(=O)cc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3925074 IC50 28.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3cccs3)cc2)C1c1cccnc1OCCO CHEMBL3674756 IC50 29.0 nM
CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCCO CHEMBL3674774 IC50 29.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3C(=O)N(C)C)cc2)s1 CHEMBL3674915 IC50 29.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccon3)cc2)C1c1ccccc1OCC1CC1 CHEMBL3679846 IC50 29.0 nM
COc1ccc([C@@H](CCO)Nc2ncnc3c2CN(c2ccc(C)cn2)CC3)cn1 CHEMBL3643342 IC50 29.0 nM
COC(=O)C[C@H](C)n1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3925069 IC50 29.0 nM
CCOc1ccc(Nc2nc(=O)n(C[C@H](C)C(=O)OC)c(=O)n2Cc2ccc(Cl)cc2)cc1C CHEMBL3891590 IC50 29.0 nM
CC(C)Oc1ccc(Nc2ncc(C(=O)NNC(=O)OC(C)(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3970429 IC50 29.0 nM
COCCOc1ncccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674772 IC50 30.0 nM
COc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 CHEMBL3674783 IC50 30.0 nM
COCCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)c2)cc1 CHEMBL3674890 IC50 30.0 nM
COCCn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3984005 IC50 30.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CC(C)(C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3985699 IC50 30.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CCC(C)(C)C(=O)OCc3ccccc3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3943044 IC50 30.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(C[C@@H](C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL4113509 IC50 30.0 nM
CCOC(=O)c1ccc(N2C(=O)C(O)=C(C(=O)c3ccc(OC)cc3)C2c2cccc(F)c2)cc1 CHEMBL4126833 IC50 30.0 nM
Cc1ccc(-c2cc(C(=O)N[C@@H](c3nc(C)no3)C3CC3)cc(-c3ncccc3F)c2)nc1 CHEMBL4226234 INH 30.0 nM
C[C@@H](Cn1c(=O)[nH]/c(=N\c2ccc(Oc3ncco3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL5088459 IC50 30.7 nM
COCc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 CHEMBL3674821 IC50 31.0 nM
CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1C(=O)N(C)C CHEMBL3674914 IC50 31.0 nM
CSc1ccc(N2C(=O)C(=O)C(C(=O)C(C)C)C2c2ccccc2OCC2CCOCC2)cc1 CHEMBL3679849 IC50 31.0 nM
CC(C)(C)c1[nH]nc2c1C(c1ccccc1OCCO)N(c1ccc(-c3ccon3)cc1)C2=O CHEMBL3679944 IC50 31.0 nM
COc1ncccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3684626 IC50 31.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2ccco2)cn1 CHEMBL3684661 IC50 31.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3970466 IC50 31.0 nM
CC(C)Oc1ccc(Nc2nc(=O)c(C(=O)NC3CCOCC3)cn2Cc2ccc(Cl)cc2)cc1F CHEMBL3904601 IC50 31.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(=O)CCO)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3898765 IC50 31.0 nM
COCCOc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)c2)cc1 CHEMBL3674792 IC50 32.0 nM
Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC(C)C)cc2)cs1 CHEMBL3674925 IC50 32.0 nM
COCCOc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3669802 IC50 32.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3CCC(N)=O)cc2)o1 CHEMBL3679798 IC50 32.0 nM
COC(=O)C(C)(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OC CHEMBL3679816 IC50 32.0 nM
CSc1ccc(N2C(=O)C(=O)C(C(=O)C(C)C)C2c2ccccc2OCC2CC2)cc1 CHEMBL3679847 IC50 32.0 nM
CC(C)(C)c1n[nH]c2c1C(c1cccc[n+]1[O-])N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679918 IC50 32.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1CO)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679930 IC50 32.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CC3CC3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3949942 IC50 32.0 nM
Cc1ccc(Cn2c(=O)n(CC(C)(C)C(=O)O)c(=O)[nH]/c2=N\c2ccc(OC(C)C)c(F)c2)cc1 CHEMBL3980669 IC50 32.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(=O)c3ccc(=O)[nH]c3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3904723 IC50 32.0 nM
CC(C)C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)O)[C@@H](C)O)C(C)C CHEMBL395723 IC50 32.4 nM
COCc1ccccc1C1C(C(=O)C2CCCC2)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679782 IC50 33.0 nM
Cc1nc(-c2ccc(N3C(=O)C(=O)C(C(=O)C4CCCC4)C3c3ccccc3OCC(C)C)cc2)no1 CHEMBL3679785 IC50 33.0 nM
CC(C)Oc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2csnn2)cc1 CHEMBL3679796 IC50 33.0 nM
CCC(CC)(CO)c1[nH]nc2c1C(c1ccccc1OC)N(c1ccc(-c3ccon3)cc1)C2=O CHEMBL3684564 IC50 33.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(SC)cc1 CHEMBL3684608 IC50 33.0 nM
CC(C)c1[nH]nc2c1C(c1cccnc1OCC(=O)O)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679903 IC50 33.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccoc2)cn1 CHEMBL3684646 IC50 33.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccco2)cn1 CHEMBL3684654 IC50 33.0 nM
C[C@@H](Nc1ncnc2c1CN(c1ccc(Cl)cn1)CC2)c1ccc(C(F)(F)F)nc1 CHEMBL3643336 IC50 33.0 nM
CCCOc1ccc(Nc2nc(=O)n(CCO)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3981348 IC50 33.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n([C@@H](C)CC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3896921 IC50 33.0 nM
COC(=O)C(C)(C)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(Cl)c2)n(CC2CCCC2)c1=O CHEMBL3987089 IC50 33.0 nM
CCOC(=O)Nc1cnc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3971042 IC50 33.0 nM
COc1ccc(OC)c(CCn2cnc3sc4c(c3c2=O)CCC(C(=O)N(C)C)C4)c1 CHEMBL4546396 IC50 33.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OC(F)(F)F CHEMBL3674820 IC50 34.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3cccnc3OCCCO)cc2)o1 CHEMBL3679744 IC50 34.0 nM
COc1ccccc1[C@@H]1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL3684628 IC50 34.0 nM
COc1ccccc1C1c2c(C(C)(C)C(=O)O)n[nH]c2C(=O)N1c1ccc(-c2cccs2)cc1 CHEMBL3684575 IC50 34.0 nM
CNC(=O)C(C)(C)c1n[nH]c2c1C(c1ccccc1OC)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3684582 IC50 34.0 nM
CC(=O)NCCn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3967291 IC50 34.0 nM
CCOC(=O)CCn1c(=O)nc(Nc2ccc(OC(C)C)c(Cl)c2)n(CC2CCCCC2)c1=O CHEMBL3973036 IC50 34.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(OCC(=O)O)nc(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3951057 IC50 34.0 nM
COC(=O)C(C)(C)Cn1c(=O)[nH]/c(=N\c2ccc3nc(C)oc3c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3920085 IC50 34.0 nM
CCOc1ccc(Nc2nc(=O)n(C[C@H](C)C(=O)OC)c(=O)n2Cc2ccc(Cl)cc2)cc1 CHEMBL3912817 IC50 34.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n2CC2CCCCC2)cc1Cl CHEMBL3958398 IC50 34.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n2CC2CCCCCC2)cc1Cl CHEMBL3949740 IC50 34.0 nM
CC(C)Oc1ccc(Nc2cc(=O)n(CCCC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL3951877 IC50 34.0 nM
CC(C)Oc1ccc(Nc2cc(=O)n(CCC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl CHEMBL4789094 IC50 34.0 nM
O=C(O)c1cc(C(=O)O)c(C(=O)N(Cc2cccc(Oc3ccccc3)c2)[C@H]2CCCc3ccccc32)cc1C(=O)O CHEMBL596234 IC50 35.0 nM
COc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)c(F)c1 CHEMBL3674762 IC50 35.0 nM
COc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674765 IC50 35.0 nM
CCOc1ncccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674943 IC50 35.0 nM
CC(C)(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccoc3)cc2)C1c1ccccc1OCCO CHEMBL3669801 IC50 35.0 nM
COCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)c2)cc1 CHEMBL3674887 IC50 35.0 nM
COCCCOc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 CHEMBL3679828 IC50 35.0 nM
CNC(=O)COc1ncccc1C1c2c(n[nH]c2C(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3639787 IC50 35.0 nM
Cc1ccc(Cn2c(=O)n(CC(=O)NCC(=O)O)c(=O)[nH]/c2=N\c2ccc(OC(C)C)c(F)c2)cc1 CHEMBL3952997 IC50 35.0 nM
Cc1ccc(Cn2c(=O)n(CC(=O)N[C@H](C)C(=O)O)c(=O)[nH]/c2=N\c2ccc(OC(C)C)c(F)c2)cc1 CHEMBL4108404 IC50 35.0 nM
CC(C)(Cn1c(=O)[nH]/c(=N\c2cccc(C(F)(F)F)c2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL3975169 IC50 35.0 nM
COCC(=O)Nc1cnc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3986399 IC50 35.0 nM
CCn1c(=O)cc(Nc2ccc(Oc3cncc(C(=O)OC)c3)cc2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3930778 IC50 35.0 nM
CC(C)(C)C(=O)C1=C(O)C(=O)N(c2ccc(-c3ccoc3)cc2)C1c1ccccc1OCCO CHEMBL4562022 IC50 35.0 nM
COc1ccc(Cl)cc1CCn1cnc2sc3c(c2c1=O)CCN(S(=O)(=O)N(C)C)C3 CHEMBL4442508 IC50 35.0 nM
CCC(=O)N1CCc2c(sc3ncn(CCc4cc(OC)ccc4OC)c(=O)c23)C1 CHEMBL4450775 IC50 35.0 nM
CC(C)COc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL3674953 IC50 36.0 nM
COc1ccc(F)cc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)o2)cc1 CHEMBL3674956 IC50 36.0 nM
COCc1ccccc1C1C(C(=O)c2cccnc2)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3674963 IC50 36.0 nM
COc1ccc(C(=O)C2C(=O)C(=O)N(c3ccc(-c4ccsc4)cc3)C2C2COC(C)(C)OC2)cn1 CHEMBL3674808 IC50 36.0 nM
COCCN(C)C(=O)c1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)c2)cc1 CHEMBL3679763 IC50 36.0 nM
COc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)c2)cc1 CHEMBL3669835 IC50 36.0 nM
COc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)o2)cc1 CHEMBL3674898 IC50 36.0 nM
CC(C)(C)c1[nH]nc2c1C(c1cccc[n+]1[O-])N(c1ccc(-c3cccs3)cc1)C2=O CHEMBL3684576 IC50 36.0 nM
COc1ncccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2cccs2)cn1 CHEMBL3684656 IC50 36.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCC(=O)NCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3901967 IC50 36.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCNC(=O)N(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3968826 IC50 36.0 nM
COC(=O)c1cccc(Cn2c(=O)[nH]/c(=N\c3ccc(OC(C)C)c(F)c3)n(Cc3ccc(Cl)cc3)c2=O)c1 CHEMBL3921619 IC50 36.0 nM
COc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)c2)cc1 CHEMBL3674781 IC50 37.0 nM
CCOc1ncccc1C1C(C(=O)C2CCCC2)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679781 IC50 37.0 nM
COCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3674865 IC50 37.0 nM
CNC(=O)NCCn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3897658 IC50 37.0 nM
COC(=O)C(C)(C)Cn1c(=O)[nH]/c(=N\c2cccc(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3980045 IC50 37.0 nM
COC(=O)C(C)(C)Cn1c(=O)[nH]/c(=N\c2cccc(OC(F)(F)F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3923287 IC50 37.0 nM
COC(=O)[C@@H](C)Cn1c(=O)cc(Nc2ccc(OC(C)C)c(C)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3939937 IC50 37.0 nM
Cc1ccc(-c2cc(C(=O)N[C@H](C)c3ccc(F)cn3)cc(-n3nccn3)c2)nc1 CHEMBL4227797 INH 37.0 nM
CCOc1ccc([C@@H](C)Nc2nc(N3CCN(C(C)=O)CC3)nc3c2CN(C(C)C)C3=O)cc1F CHEMBL2011123 IC50 38.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCO)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3946453 IC50 38.0 nM
CCn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3945216 IC50 38.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCNC(=O)NCC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3912302 IC50 38.0 nM
COCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(C2=CCCC2)cc1 CHEMBL3679791 IC50 39.0 nM
COCCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3669839 IC50 39.0 nM
COc1ncccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccsc2)cn1 CHEMBL3684658 IC50 39.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(Cc3ccccc3C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3956365 IC50 39.0 nM
CCC(CC)C1C(C(=O)c2ccc(C(=O)N(C)C)cc2)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL3669696 IC50 40.0 nM
COc1ccc(C(=O)C2C(=O)C(=O)N(c3ccc(-c4cc(C)no4)cc3)C2c2ccccc2OC)cc1 CHEMBL3669712 IC50 40.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccoc3)cc2)C1c1ccccc1OCCO CHEMBL3669829 IC50 40.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3OC(F)(F)F)cc2)o1 CHEMBL3674877 IC50 40.0 nM
Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3OCCO)cc2)cs1 CHEMBL3674889 IC50 40.0 nM
CSc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)c2)cc1 CHEMBL3679819 IC50 40.0 nM
COc1ccccc1[C@@H]1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3669840 IC50 40.0 nM
CNC(=O)Cn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3913107 IC50 40.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1 CHEMBL3950974 IC50 40.0 nM
O=c1nc(Nc2cccc(C(F)(F)F)c2)n(Cc2ccc(Cl)cc2)c(=O)n1CC(CO)CO CHEMBL3910124 IC50 40.0 nM
Cc1cc(/N=c2\[nH]c(=O)n([C@H](C)CC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)ccc1OC(C)C CHEMBL4114104 IC50 40.0 nM
Cc1nc2ccc(Nc3nc(=O)c(C(=O)NC(C)C)cn3Cc3ccc(Cl)cc3)cc2s1 CHEMBL3894301 IC50 40.0 nM
COc1cc(CCn2cnc3sc4c(c3c2=O)CCN(C(=O)CC(C)C)C4)cc(OC)c1 CHEMBL4444041 IC50 40.0 nM
COc1cc(CCn2cnc3sc4c(c3c2=O)CCN(C(=O)C2CCC2)C4)cc(OC)c1 CHEMBL4549131 IC50 40.0 nM
COc1cc(CCn2cnc3sc4c(c3c2=O)CCN(S(C)(=O)=O)C4)cc(OC)c1 CHEMBL4515308 IC50 40.0 nM
COc1cc(CCn2cnc3sc4c(c3c2=O)CCN(S(=O)(=O)C2CCCC2)C4)cc(OC)c1 CHEMBL4440083 IC50 40.0 nM
COc1ccc(F)cc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)c2)cc1 CHEMBL3674955 IC50 41.0 nM
COCc1ncccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669806 IC50 41.0 nM
COc1ccccc1C1c2c(C(C)(C)C(=O)O)n[nH]c2C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3684577 IC50 41.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CC(CO)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1 CHEMBL3900094 IC50 41.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCNC(N)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3949879 IC50 41.0 nM
CSc1ccc(N2C(=O)C(=O)C(C(=O)CC(C)C)C2c2ccccc2OC(C)C)cc1 CHEMBL3674939 IC50 42.0 nM
COc1ccc(C(=O)C2C(=O)C(=O)N(c3ccc(-c4cc(C)on4)cc3)C2c2ccccc2OC)cc1 CHEMBL3679746 IC50 42.0 nM
COCCOc1ccccc1C1C(S(=O)(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679822 IC50 42.0 nM
CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(C3=NCCS3)cc2)C1c1ccccc1OC(C)C CHEMBL3674920 IC50 42.0 nM
Cc1cc(/N=c2\[nH]c(=O)n(C[C@@H](C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)ccc1OC(C)C CHEMBL4106888 IC50 42.0 nM
COCCOc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccco2)cc1 CHEMBL3669780 IC50 43.0 nM
COCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3669841 IC50 43.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2ccoc2)cn1 CHEMBL3684648 IC50 43.0 nM
Cc1ccc(N2CCc3ncnc(NC(C)c4ccc(Cl)c(F)c4)c3C2)nc1 CHEMBL3643327 IC50 43.0 nM
CC(=O)Nc1cnc(Nc2ccc(Oc3ccc(C)nc3)cc2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3925342 IC50 43.0 nM
COCc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccco2)cc1 CHEMBL3674870 IC50 44.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3C(=O)N(C)C)cc2)o1 CHEMBL3674909 IC50 44.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2nc(C)no2)cc1 CHEMBL3684560 IC50 44.0 nM
CC(=O)N(C)c1ccccc1C1c2c(n[nH]c2C(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679926 IC50 44.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CC(=O)NCC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3905952 IC50 44.0 nM
COC(=O)Cn1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(F)c2)n(Cc2ccc(C)cc2)c1=O CHEMBL3901654 IC50 44.0 nM
COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccc(-c4ccon4)cc3)C2C2CCCCC2)cn1 CHEMBL4458893 IC50 44.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3978482 IC50 45.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCC(=O)N(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3940146 IC50 45.0 nM
Cc1ccc(-c2cc(C(=O)NCCc3nc(C)no3)cc(-c3ncccc3F)c2)nc1 CHEMBL4228197 INH 45.0 nM
COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1S(N)(=O)=O CHEMBL3716057 IC50 45.0 nM
COc1ccc(OC)c(CCn2cnc3ccc(-c4ccccc4OC)cc3c2=O)c1 CHEMBL4577427 IC50 45.0 nM
COc1ccc(OC)c(CCn2cnc3ccc(-c4cccc(C(N)=O)c4)cc3c2=O)c1 CHEMBL4457753 IC50 45.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1cccnc1OCCO CHEMBL3669817 IC50 46.0 nM
COCCOc1ncccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(SC)cc1 CHEMBL3679885 IC50 46.0 nM
CSc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL3679943 IC50 46.0 nM
COc1cc(F)ccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL3679908 IC50 46.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CC(N)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3897564 IC50 46.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCC(N)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3933324 IC50 46.0 nM
CC(C)Cc1ccc(Nc2nc(=O)n(CC(CO)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1 CHEMBL3971244 IC50 46.0 nM
COC(=O)C(C)(C)Cn1c(=O)[nH]/c(=N\c2ccc(CN(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3962073 IC50 46.0 nM
CCOc1ccc(/N=c2\[nH]c(=O)n(C[C@H](C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1C CHEMBL3954969 IC50 46.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1C(=O)N(C)C CHEMBL3674770 IC50 47.0 nM
CCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3674863 IC50 47.0 nM
COc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 CHEMBL3669846 IC50 47.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3cccnc3C(=O)NCC#N)cc2)s1 CHEMBL3679836 IC50 47.0 nM
Cc1ccc([C@@H](C)Nc2ncnc3c2CN(c2ccc(C)cn2)CC3)cc1 CHEMBL3643324 IC50 47.0 nM
O=c1nc(Nc2cccc(C(F)(F)F)c2)n(Cc2ccc(Cl)cc2)c(=O)n1CCCO CHEMBL3959694 IC50 47.0 nM
COC(=O)C(C)(C)Cn1c(=O)[nH]/c(=N\c2ccc(Cl)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3931300 IC50 47.0 nM
CC(C)Oc1ccc(Nc2ncc(C(N)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3985030 IC50 47.0 nM
Cc1ccc(-c2cc(C(=O)N[C@H](C)c3ccc(F)cn3)cc(N3CCOCC3)c2)nc1 CHEMBL4225135 INH 47.0 nM
COc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3669740 IC50 48.0 nM
CC(C)(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccco3)cc2)C1c1ccccc1OCCO CHEMBL3669746 IC50 48.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3OC(F)F)cc2)o1 CHEMBL3674876 IC50 48.0 nM
Cc1ccc(N2CCc3ncnc(N[C@H](C)c4ccc(Cl)cc4)c3C2)nc1 CHEMBL3643307 IC50 48.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(Cc3ccccc3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3968529 IC50 48.0 nM
Cc1cc2cc(/N=c3\[nH]c(=O)n(C[C@@H](C)C(=O)O)c(=O)n3Cc3ccc(Cl)cc3)ccc2o1 CHEMBL4111869 IC50 48.0 nM
CCOC(=O)C1CCc2c(sc3ncn(CCc4cc(OC)ccc4OC)c(=O)c23)C1 CHEMBL4547802 IC50 48.0 nM
COc1ccc(C(=O)C2C(=O)C(=O)N(c3ccc(-c4ccon4)cc3)C2c2ccccc2OCCO)cc1 CHEMBL3669775 IC50 49.0 nM
CNC(=O)CCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)o2)cc1 CHEMBL3679797 IC50 49.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CC3(C(=O)O)CC3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3952870 IC50 49.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(=O)CC3CCOCC3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3947593 IC50 49.0 nM
CC(C)Oc1ccc(Nc2ncc(NC(N)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3978723 IC50 49.0 nM
COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccc(-c4ccon4)cc3)C2c2ccccc2OCCO)cc1 CHEMBL4557885 IC50 49.0 nM
Cc1ccc(N2CCc3ncnc(NC(C)c4ccc(F)cc4F)c3C2)nc1 CHEMBL3643318 IC50 50.0 nM
Cc1cc(/N=c2\[nH]c(=O)n(CCCC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)ccc1OC(C)C CHEMBL3895960 IC50 50.0 nM
CCOC(=O)c1cnc(Nc2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3979348 IC50 50.0 nM
CC(C)Oc1ccc(Nc2ncc(N(C)C(=O)OC(C)(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3925514 IC50 50.0 nM
COc1cc(CCn2cnc3sc4c(c3c2=O)CCN(S(=O)(=O)N(C)C)C4)cc(OC)c1 CHEMBL4460871 IC50 50.0 nM
CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OC(F)F CHEMBL3674809 IC50 51.0 nM
CSc1ccc(N2C(=O)C(=O)C(C(=O)C(C)C)C2c2ccccc2OCCCO)cc1 CHEMBL3679742 IC50 51.0 nM
Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3OC(C)C)cc2)cs1 CHEMBL3674888 IC50 51.0 nM
COC(=O)C(C)(C)Cn1c(=O)cc(Nc2cccc(C(F)(F)F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3979976 IC50 51.0 nM
CCOC(=O)CCC1=CN(Cc2ccc(Cl)cc2)C(Nc2ccc(OC(C)C)c(Cl)c2)=NC1O CHEMBL3911709 IC50 51.0 nM
Cc1nc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OCC3OCCO3)cc2)no1 CHEMBL3679767 IC50 52.0 nM
Cc1ccc(N2CCc3ncnc(NC(C)c4cc(F)cc(F)c4)c3C2)nc1 CHEMBL3643317 IC50 52.0 nM
CCOc1ccc(/N=c2\[nH]c(=O)n(C[C@H](C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1 CHEMBL3982396 IC50 52.0 nM
O=C(C1=C(O)C(=O)N(c2ccc(-c3ccon3)cc2)C1C1CCCCC1)c1ccc(CO)cc1 CHEMBL4585133 IC50 52.0 nM
COc1ccc(C(=O)C2C(=O)C(=O)N(c3ccc(-c4noc(C)n4)cc3)C2c2ccccc2OC)cc1 CHEMBL3669715 IC50 53.0 nM
COc1ccc(C(=O)C2C(=O)C(=O)N(c3ccc(-c4nnc(C)o4)cc3)C2c2ccccc2OC)cc1 CHEMBL3669718 IC50 53.0 nM
CCN(C)C(=O)c1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)c2)cc1 CHEMBL3679760 IC50 53.0 nM
COC(=O)Cn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3950749 IC50 53.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CCC(C)(C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3938849 IC50 53.0 nM
Cc1cc(/N=c2\[nH]c(=O)n([C@@H](C)CC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)ccc1OC(C)C CHEMBL3928431 IC50 53.0 nM
CC(C)Oc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL3674813 IC50 54.0 nM
CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccon3)cc2)C1c1ccccc1OC(C)C CHEMBL3674824 IC50 54.0 nM
Cc1nc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC(C)C)cc2)no1 CHEMBL3674830 IC50 54.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(SC)cc1 CHEMBL3679860 IC50 54.0 nM
Cc1nc(-c2ccc(N3C(=O)c4n[nH]c(C(C)(C)C)c4C3c3ccccc3OCCO)cc2)no1 CHEMBL3679868 IC50 54.0 nM
Cc1ccc(Cn2c(=O)n(CCCC(=O)O)c(=O)[nH]/c2=N\c2ccc(OC(C)C)c(C)c2)cc1 CHEMBL3953114 IC50 54.0 nM
CC(C)Oc1ccc(Nc2ncc(C(=O)OC(C)(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3908912 IC50 54.0 nM
COCCN(C)C(=O)c1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)o2)cc1 CHEMBL3679762 IC50 55.0 nM
COCCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3674864 IC50 55.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2cc(C)no2)cc1 CHEMBL3684558 IC50 55.0 nM
CC(C)Cc1ccc(Nc2nc(=O)n(CCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1 CHEMBL3983044 IC50 55.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CCC(=O)NCC(N)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3906063 IC50 55.0 nM
CC(C)Oc1ccc(Nc2cc(=O)n(C[C@H](C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1 CHEMBL3960316 IC50 55.0 nM
CC(C)Oc1ccc(Nc2ncc(C(=O)NNC=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3895407 IC50 55.0 nM
COc1cc(CCn2cnc3sc4c(c3c2=O)CCN(C(=O)C(C)(C)O)C4)cc(OC)c1 CHEMBL4563035 IC50 55.0 nM
COCCOc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3674761 IC50 56.0 nM
Cc1ccc(N2CCc3ncnc(NC(C)c4cccc(F)c4)c3C2)nc1 CHEMBL3643303 IC50 56.0 nM
CC(C)(Cn1c(=O)[nH]/c(=N\c2ccc(Cl)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O CHEMBL3972022 IC50 56.0 nM
COCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccco2)cc1 CHEMBL3674869 IC50 57.0 nM
COCCCOc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3679826 IC50 57.0 nM
COc1ncccc1C1c2c(n[nH]c2C(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3679899 IC50 57.0 nM
CCOc1ccc(/N=c2\[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1C CHEMBL3947688 IC50 57.0 nM
Cc1nc2ccc(Nc3cc(=O)n(CCO)c(=O)n3Cc3ccc(Cl)cc3)cc2s1 CHEMBL3962024 IC50 57.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC(F)F)cc2)s1 CHEMBL3674851 IC50 58.0 nM
CCOCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2noc(C)n2)cc1 CHEMBL3679804 IC50 58.0 nM
CC(C)Oc1ccc(/N=c2\[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1 CHEMBL3907849 IC50 58.0 nM
CCN(C)C(=O)c1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)o2)cc1 CHEMBL3679761 IC50 59.0 nM
CC(C)Oc1ccc(Nc2ncc(C(=O)NC(CO)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3903511 IC50 59.0 nM
Cc1nc(Cc2cccc(Oc3ccccc3)c2)c(/C=C/C(=O)O)c(C=O)c1O CHEMBL3091630 IC50 60.0 nM
COCCCOc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)c2)cc1 CHEMBL3679830 IC50 60.0 nM
COc1ccccc1C1c2c(CO)n[nH]c2C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3684592 IC50 60.0 nM
COC(=O)C[C@H](C)n1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(C)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3952771 IC50 60.0 nM
COc1cc(CCn2cnc3ccc(-c4c(C)noc4C)cc3c2=O)cc(OC)c1 CHEMBL4437458 IC50 60.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccoc3)cc2)C1c1cccnc1OCCCO CHEMBL3679825 IC50 61.0 nM
Cc1ccc(Cn2c(=O)n(CCC(=O)O)c(=O)[nH]/c2=N\c2ccc(OC(C)C)c(F)c2)cc1 CHEMBL3943886 IC50 61.0 nM
COC(=O)C(C)(C)Cn1c(=O)cc(Nc2cccc(C(F)(F)F)n2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3944069 IC50 61.0 nM
Cc1nc2ccc(Nc3nc(=O)c(C(=O)NC4CC4)cn3Cc3ccc(Cl)cc3)cc2s1 CHEMBL3903279 IC50 61.0 nM
CC(C)Oc1ccccc1C1C(C(=O)C2CCCC2)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL3679778 IC50 62.0 nM
Cc1nc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3COC(C)C)cc2)no1 CHEMBL3679801 IC50 62.0 nM
COc1ncccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(SC)cc1 CHEMBL3679859 IC50 62.0 nM
COCCOc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2nc(C)no2)cc1 CHEMBL3679875 IC50 62.0 nM
CC(C)Oc1ccc(Nc2ncc(NS(C)(=O)=O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3959741 IC50 62.0 nM
COCc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669833 IC50 63.0 nM
Cc1ccc(N2CCc3ncnc(NC(C)c4cccnc4)c3C2)nc1 CHEMBL3643311 IC50 63.0 nM
CCOc1ccc(Nc2nc(=O)n(CC(CO)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1 CHEMBL3951408 IC50 63.0 nM
COc1ccccc1C1c2c(C(C)(C)CO)n[nH]c2C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL4797432 IC50 63.0 nM
CC(=O)N1CCN(c2nc(N[C@H](C)c3ccc(OC(F)(F)F)cc3)c3c(n2)C(=O)N(C(C)C)C3)CC1 CHEMBL2011118 IC50 64.0 nM
COc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3669836 IC50 64.0 nM
CCNC(=O)NCCn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3934771 IC50 64.0 nM
CC(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccco3)cc2)C1c1ccccc1OCCO CHEMBL3674753 IC50 65.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3OCCO)cc2)s1 CHEMBL3674846 IC50 65.0 nM
CC(C)COc1ccccc1C1C(C(=O)C2CCCC2)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL3679779 IC50 65.0 nM
CC(C)c1[nH]nc2c1C(c1ccccc1CC(=O)O)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3679938 IC50 65.0 nM
COc1cc(CCn2cnc3sc4c(c3c2=O)CCC2(C4)OCCO2)cc(OC)c1 CHEMBL4572174 IC50 65.0 nM
COc1ccc(OC)c(CCn2cnc3ccc(-c4cc(OC)ccc4OC)cc3c2=O)c1 CHEMBL4514350 IC50 65.0 nM
COc1ccc(OC)c(CCn2ccc3ccc(-c4ccccc4S(N)(=O)=O)cc3c2=O)c1 CHEMBL4471517 IC50 65.0 nM
CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccoc3)cc2)C1c1ccccc1OCCO CHEMBL3674866 IC50 66.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3cccnc3OCCCO)cc2)s1 CHEMBL3679827 IC50 66.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3947017 IC50 66.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CC(C)(C)CN)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3936439 IC50 66.0 nM
COc1ccc(C(=O)Nc2cnc(Nc3ccc(OC(C)C)c(F)c3)n(Cc3ccc(Cl)cc3)c2=O)cn1 CHEMBL3958086 IC50 66.0 nM
COc1cc(OC(F)(F)F)ccc1CNc1nc(N2CCN(C(C)=O)CC2)nc2c1CN(C(C)C)C2=O CHEMBL2011116 IC50 67.0 nM
Cc1nc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3N3CCOCC3)cc2)no1 CHEMBL3679754 IC50 67.0 nM
Cc1nc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC3CCOCC3)cc2)no1 CHEMBL3679768 IC50 67.0 nM
CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccoc3)cc2)C1c1ccccc1OC(F)F CHEMBL3674858 IC50 67.0 nM
Cc1ccc(N2CCc3ncnc(NC(CCO)c4ccc(C(F)(F)F)nc4)c3C2)nc1 CHEMBL3643340 IC50 67.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCNC(=O)NCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3974099 IC50 67.0 nM
CC(C)Oc1ccc(Nc2ncc(C(=O)NC3CCOCC3)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3985303 IC50 67.0 nM
Cc1ccc(-c2cc(C(=O)N[C@H](C)c3ccc(F)cn3)cc(C(C)(C)O)c2)nc1 CHEMBL4226706 INH 67.0 nM
CCOc1ccc([C@@H](C)Nc2nc(N3CCN(C(C)=O)CC3)nc3c2CN(C(C)C)C3=O)cc1 CHEMBL2011120 IC50 69.0 nM
COc1ncccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3684624 IC50 69.0 nM
Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC(F)F)cc2)cs1 CHEMBL3674839 IC50 70.0 nM
CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OC(F)(F)F CHEMBL3674848 IC50 70.0 nM
COCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(C2CCCC2)cc1 CHEMBL3679792 IC50 70.0 nM
Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3cccnc3OCCCO)cc2)cs1 CHEMBL3679829 IC50 70.0 nM
CSc1ccc(N2C(=O)c3n[nH]c(C(C)(C)C)c3C2c2cccnc2OCCO)cc1 CHEMBL3679891 IC50 70.0 nM
CSc1ccc(N2C(=O)C(=O)C(C(=O)C(C)C)C2c2ccccc2OC(C)C)cc1 CHEMBL3679740 IC50 71.0 nM
Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3C(=O)N(C)C)cc2)cs1 CHEMBL3674913 IC50 71.0 nM
Cc1ccc(Cn2c(=O)n(CC(=O)NC3(C(=O)O)CC3)c(=O)[nH]/c2=N\c2ccc(OC(C)C)c(F)c2)cc1 CHEMBL3962767 IC50 71.0 nM
CCOC(=O)c1cnc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3926669 IC50 71.0 nM
COC(=O)C[C@H](C)n1c(=O)[nH]/c(=N\c2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3899874 IC50 72.0 nM
CC(C)(CN1C(=O)N(Cc2ccc(Cl)cc2)C(Nc2cccc(C(F)(F)F)c2)=CC1O)C(=O)O CHEMBL3920643 IC50 72.0 nM
COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccc(-c4nnc(C)o4)cc3)C2C2CCCCC2)cc1 CHEMBL4126038 IC50 72.0 nM
COc1ccccc1C1c2c(C(C)(C)C)n[nH]c2C(=O)N1c1ccc(-c2cc(C)no2)cc1 CHEMBL4750518 IC50 72.0 nM
Cc1nc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3OC(C)C)cc2)no1 CHEMBL3674835 IC50 73.0 nM
CN(C)C(=O)COc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669794 IC50 73.0 nM
COc1ccccc1C1C(C(=O)C2CC2)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669854 IC50 73.0 nM
COc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccco2)cc1 CHEMBL3674752 IC50 73.0 nM
Cc1ccc(N2CCc3ncnc(N[C@H](C)c4ccccc4)c3C2)nc1 CHEMBL3643308 IC50 73.0 nM
CN(C)C(=O)COc1ccccc1C1C(C(=O)C(C)(C)C)=C(O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL4459015 IC50 73.0 nM
CC(C)(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCC(=O)O CHEMBL3669769 IC50 74.0 nM
COCCOc1ncccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 CHEMBL3669807 IC50 74.0 nM
COC(=O)C(C)(C)Cn1c(=O)[nH]/c(=N\c2ccc(C)c(C)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3942370 IC50 74.0 nM
CC(C)(C)C(=O)C1=C(O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OCC(=O)O CHEMBL4445659 IC50 74.0 nM
COc1ccc(C(=O)C2C(=O)C(=O)N(c3ccc(C4=NCCS4)cc3)C2c2ccccc2OC)cc1 CHEMBL3669713 IC50 75.0 nM
COc1ccccc1C1c2c(n[nH]c2C2(CO)CCCCC2)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL3679912 IC50 75.0 nM
CC(C)(C)c1[nH]nc2c1C(c1ccccc1OC(F)F)N(c1ccc(-c3ccon3)cc1)C2=O CHEMBL3679946 IC50 76.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(N(C)C)cc1 CHEMBL3684609 IC50 76.0 nM
CCOc1ccc(Nc2nc(=O)n(CCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1 CHEMBL3945693 IC50 76.0 nM
COc1ncccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669765 IC50 77.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3S(C)(=O)=O)cc2)o1 CHEMBL3679809 IC50 77.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC(F)(F)F)cc2)s1 CHEMBL3674852 IC50 78.0 nM
CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccoc3)cc2)C1c1ccccc1OC(F)(F)F CHEMBL3674859 IC50 78.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCCC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3939178 IC50 78.0 nM
O=C1C(=O)N(c2ccc(-c3ccon3)cc2)C(C2CCCCC2)C1C(=O)c1ccc(Br)cc1 CHEMBL3669707 IC50 79.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3C(=O)N(C)C)cc2)s1 CHEMBL3674911 IC50 79.0 nM
CC(C)Oc1ccc(Nc2nc(OCCO)nc(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3937780 IC50 79.0 nM
Cc1nc(/N=N/c2ccc(C(=O)O)cc2)c(CCC(=O)O)c(C=O)c1O CHEMBL2376118 IC50 79.8 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1OC(=O)c1ccc(-c2ccccc2)cc1 CHEMBL339386 EC50 80.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3OC(C)C)cc2)s1 CHEMBL3674912 IC50 80.0 nM
COc1ccc(C(C)Nc2ncnc3c2CN(c2ccc(C)cn2)CC3)cc1F CHEMBL3643319 IC50 80.0 nM
O=c1nc(Nc2ccc(OC3CCCC3)c(Cl)c2)n(Cc2ccc(Cl)cc2)c(=O)n1CCO CHEMBL3986334 IC50 80.0 nM
COC(=O)C(C)(C)Cn1c(=O)[nH]/c(=N\c2ccc3[nH]ccc3c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3970025 IC50 80.0 nM
Cc1ccc(Cn2c(=O)n(CCCC(=O)O)c(=O)[nH]/c2=N\c2ccc3oc(C)cc3c2)cc1 CHEMBL3938311 IC50 80.0 nM
COc1cc(CCn2cnc3ccc(-c4cn[nH]c4C)cc3c2=O)cc(OC)c1 CHEMBL4557775 IC50 80.0 nM
COc1cc(N2C(=O)C(=O)C(C(=O)C(C)C)C2c2ccccc2OC)ccc1-c1ccsc1 CHEMBL3674749 IC50 81.0 nM
CC(C)(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccon3)cc2)C1c1ccccc1OCCO CHEMBL3669732 IC50 82.0 nM
COCCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(SC)cc1 CHEMBL3674938 IC50 82.0 nM
COCCOc1cc(F)ccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2noc(C)n2)cc1 CHEMBL3674880 IC50 82.0 nM
COC(=O)n1nc(C(C)(C)C)c2c1C(=O)N(c1ccc(Br)cc1)C2c1ccccc1OC CHEMBL3684629 IC50 82.0 nM
C[C@@H](NC(=O)c1cc(-c2ccc(F)cn2)cc(C(C)(C)O)c1)c1ccc(C(F)(F)F)[n+]([O-])c1 CHEMBL4228403 INH 82.0 nM
CC(C)(C)C(=O)C1=C(O)C(=O)N(c2ccc(-c3ccon3)cc2)C1c1ccccc1OCCO CHEMBL4565775 IC50 82.0 nM
CC(C)C[C@@H]1NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC1=O CHEMBL397926 IC50 82.4 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3CCC(=O)N(C)C)cc2)o1 CHEMBL3679799 IC50 83.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCO)c(=O)n2Cc2ccc(Cl)cc2)cc1 CHEMBL3921233 IC50 83.0 nM
Cc1nc(/N=N/c2cc(S(=O)(=O)O)ccc2S(=O)(=O)O)c(COP(=O)(O)O)c(C=O)c1O CHEMBL69727 IC50 84.0 nM
COc1cc(CCn2cnc3sc4c(c3c2=O)CCN(C(=O)C2(O)CC2)C4)cc(OC)c1 CHEMBL4440963 IC50 85.0 nM
COc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669826 IC50 86.0 nM
CNC(=O)O[C@@H](CC(C)C)c1nc([C@H]2OC(=O)/C(C)=C/C/C(C)=C/[C@@H](O)[C@@H](C)/C=C(C)\C=C(C)/C=C/[C@@H](O)[C@H](C)[C@H](OC)/C(C)=C/C=C/[C@@H]2C)cs1 CHEMBL241106 IC50 86.1 nM
Cc1nc(-c2ccc(N3C(=O)C(=O)C(C(=O)C4CCCC4)C3c3ccccc3OC(C)C)cc2)no1 CHEMBL3679784 IC50 87.0 nM
Cc1cc(-c2ccc(N3C(=O)c4n[nH]c(C(C)(C)C)c4C3c3ccccc3OCCO)cc2)on1 CHEMBL3679866 IC50 87.0 nM
COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ncco2)cc1 CHEMBL3684614 IC50 87.0 nM
CC(=O)N1CCC(NC(=O)c2cn(Cc3ccc(Cl)cc3)c(Nc3ccc4nc(C)sc4c3)nc2=O)CC1 CHEMBL3956172 IC50 87.0 nM
CC(C)(C)c1[nH]nc2c1C(c1ccccc1C(=O)O)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3684556 IC50 88.0 nM
Cc1ccc(N2CCc3ncnc(NC(C)c4ccccc4F)c3C2)nc1 CHEMBL3643312 IC50 88.0 nM
Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3cccnc3OCCO)cc2)o1 CHEMBL3679749 IC50 89.0 nM
CC(C)(C)c1[nH]nc2c1C(c1ccccc1OCC(=O)O)N(c1ccc(-c3ccon3)cc1)C2=O CHEMBL3679880 IC50 90.0 nM
COc1ccc([C@@H](CO)Nc2ncnc3c2CN(c2ccc(Cl)cn2)CC3)cn1 CHEMBL3643343 IC50 90.0 nM
CCOC(=O)c1ccc(N2C(=O)C(O)=C(C(=O)c3ccc(OC)cc3)C2c2ccccc2Cl)cc1 CHEMBL4127346 IC50 90.0 nM
COCCOc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2noc(C)n2)cc1 CHEMBL3669777 IC50 91.0 nM
COCCCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(SC)cc1 CHEMBL3679750 IC50 91.0 nM
COCCOc1cc(F)ccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2noc(C)n2)cc1 CHEMBL3674884 IC50 91.0 nM
COc1ncccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2ccco2)cc1 CHEMBL3684540 IC50 91.0 nM
COc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccco2)cc1 CHEMBL3669750 IC50 92.0 nM
CC(=O)N(C)c1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 CHEMBL3669848 IC50 92.0 nM
CC(C)c1[nH]nc2c1C(c1ccccn1)N(c1ccc(-c3ccsc3)cc1)C2=O CHEMBL3684632 IC50 92.0 nM
CC(C)Oc1ccc(Nc2nc(=O)c(NC(=O)OC(C)(C)C)cn2Cc2ccc(Cl)cc2)cc1F CHEMBL3984951 IC50 92.0 nM
COc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 CHEMBL3674845 IC50 93.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CC#N)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3943367 IC50 93.0 nM
Cc1nc2ccc(Nc3cc(=O)n(CCCC(=O)O)c(=O)n3Cc3ccc(Cl)cc3)cc2s1 CHEMBL3896517 IC50 94.0 nM
CC(C)(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3ccoc3)cc2)C1c1cccnc1OCCO CHEMBL3669808 IC50 95.0 nM
COc1cc(C(=O)Nc2cnc(Nc3ccc(OC(C)C)c(F)c3)n(Cc3ccc(Cl)cc3)c2=O)ccn1 CHEMBL3962834 IC50 95.0 nM
COc1cc(CCn2cnc3ccc(-c4ccccc4S(=O)(=O)N(C)C)cc3c2=O)cc(OC)c1 CHEMBL4475432 IC50 95.0 nM
COc1ccccc1C1c2c(C(C)(C)C)n[nH]c2C(=O)N1c1ccc(-c2nc(C)no2)cc1 CHEMBL4745262 IC50 95.0 nM
CC(C)Oc1ccc(Nc2nc(=O)n(CCC(=O)O)c(=O)n2CC2CCCCC2)cc1Cl CHEMBL3948852 IC50 96.0 nM
CCOc1ccc(/N=c2\[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1 CHEMBL3937488 IC50 96.0 nM
COC(=O)Cn1c(=O)cc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL3889788 IC50 96.0 nM
CC(C)Oc1ccc(Nc2ncc(C(=O)NCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1F CHEMBL3965098 IC50 96.0 nM
CC(C)Oc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 CHEMBL3669758 IC50 97.0 nM
Cc1cc(/N=c2\[nH]c(=O)n(C[C@H](C)C(=O)O)c(=O)n2CC2CCCCC2)ccc1OC(C)C CHEMBL3907009 IC50 97.0 nM
CC(C)(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3cccs3)cc2)C1c1ccccc1OCC(=O)O CHEMBL3669768 IC50 98.0 nM
CSc1cccc(/N=c2\[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)c1 CHEMBL3937073 IC50 98.0 nM
COC(=O)[C@@H](C)NC(=O)c1cnc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O CHEMBL4112075 IC50 98.0 nM
O=c1nc(Nc2ccc(Oc3ccccc3)cc2)n(Cc2ccc(Cl)cc2)c(=O)n1CCO CHEMBL3913907 IC50 99.0 nM
Cc1ccc(Cn2c(=O)n(CC(C)(C)C(=O)O)c(=O)[nH]/c2=N\c2ccc(OC(C)C)c(F)c2)cc1F CHEMBL3892701 IC50 99.0 nM