NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1OCc1ccccc1 CHEMBL4471140 IC50 2.0 nM
COc1ccccc1CC(=O)Nc1ccc(Oc2cccc(Cl)c2)c(S(N)(=O)=O)c1 CHEMBL4452312 IC50 2.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1OCC1CCC1 CHEMBL4589444 IC50 5.0 nM
COc1cccc(Oc2ccc(NC(=O)Cc3ccccc3Cl)cc2S(N)(=O)=O)c1 CHEMBL4579583 IC50 8.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2c(F)cccc2Cl)ccc1Oc1cccc(Cl)c1 CHEMBL4447043 IC50 9.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1Oc1ccccc1 CHEMBL4556573 IC50 10.0 nM
Cc1ccccc1CC(=O)Nc1ccc(Oc2cccc(Cl)c2)c(S(N)(=O)=O)c1 CHEMBL4522504 IC50 10.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2c(F)cccc2Cl)ccc1OCC1CCOCC1 CHEMBL4555657 IC50 13.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1Oc1ccccc1Cl CHEMBL4516176 IC50 13.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2c(Cl)cccc2Cl)ccc1Oc1cccc(Cl)c1 CHEMBL4521017 IC50 15.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1OCCc1ccccc1 CHEMBL4563994 IC50 19.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2C(F)(F)F)ccc1Oc1cccc(Cl)c1 CHEMBL4438327 IC50 24.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1OCc1ccccn1 CHEMBL4439570 IC50 26.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1Oc1cncc(Cl)c1 CHEMBL4535761 IC50 27.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1Oc1ccc(-c2nccs2)cc1 CHEMBL4463320 IC50 30.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2cccc(F)c2Cl)ccc1OCC1CCOCC1 CHEMBL4517831 IC50 37.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1OC1CCCCC1 CHEMBL4539658 IC50 39.0 nM
CC(C)c1ccc(NC(=S)NC(=O)c2ccc3c(c2)OCO3)c(Br)c1 CHEMBL5206892 IC50 39.0 nM
CC(C)c1ccc(NC(=S)NC(=O)C23CC4CC(CC(C4)C2)C3)c(Br)c1 CHEMBL5204261 IC50 40.0 nM
O=C(Nc1cc([N+](=O)[O-])cc(C(F)(F)F)c1)c1cc(Cl)ccc1O CHEMBL4640175 IC50 42.6 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1Oc1cccc(C(=O)N2CCOCC2)c1 CHEMBL4474747 IC50 45.0 nM
O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cccc(Cl)c1O CHEMBL2338695 IC50 48.8 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@H]2OC3(O[C@H]21)C([N+](=O)[O-])=CC(=[N+]([O-])[O-])C=C3[N+](=O)[O-] CHEMBL1163419 Ki 48.9 nM
Cc1cccc(CC(=O)Nc2ccc(Oc3cccc(Cl)c3)c(S(N)(=O)=O)c2)c1 CHEMBL4443234 IC50 52.0 nM
O=C1CC(=O)N(c2ccc(NS(=O)(=O)Cc3ccccc3Cl)cc2)c2ccc3ccccc3c2N1 CHEMBL4557633 IC50 54.0 nM
O=C(NC(=S)Nc1c(Br)ccc(C(F)(F)F)c1Br)c1ccc2c(c1)OCO2 CHEMBL5200114 IC50 55.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1Oc1cccc(-n2cnnc2)c1 CHEMBL4438981 IC50 67.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1Oc1ccc(C2CCOC2)cc1 CHEMBL4561582 IC50 75.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2F)ccc1Oc1cccc(Cl)c1 CHEMBL4516450 IC50 76.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2cc(F)ccc2Cl)ccc1OCC1CCOCC1 CHEMBL4452251 IC50 84.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2C(F)(F)F)ccc1OCC1CCOCC1 CHEMBL4519162 IC50 88.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1Oc1cccc(Cl)c1 CHEMBL4449416 IC50 92.0 nM
CC(=O)Nc1cccc(Oc2ccc(NC(=O)Cc3ccccc3Cl)cc2S(N)(=O)=O)c1 CHEMBL4579675 IC50 93.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2)ccc1Oc1cccc(Cl)c1 CHEMBL4521594 IC50 108.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2C(F)F)ccc1OCC1CCOCC1 CHEMBL4469574 IC50 111.0 nM
CC(C(=O)Nc1ccc(Oc2cccc(Cl)c2)c(S(N)(=O)=O)c1)c1ccccc1Cl CHEMBL4593104 IC50 134.0 nM
O=C(Nc1cccc(Cl)c1)c1cc(Cl)ccc1O CHEMBL2088011 IC50 135.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1OCC1CCOCC1 CHEMBL4442297 IC50 139.0 nM
CC(=O)N(c1ccc2ncoc2c1)c1cc(NC(=O)Cc2c(Cl)cccc2Cl)ccn1 CHEMBL5208843 IC50 141.0 nM
CC(=O)N(c1ccc2ncsc2c1)c1cc(NC(=O)Cc2ccccc2Cl)ccn1 CHEMBL5180532 IC50 142.0 nM
CC(=O)N(c1ccc2ncoc2c1)c1cc(NC(=O)Cc2cccc(F)c2Cl)ccn1 CHEMBL5208382 IC50 143.0 nM
O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1O CHEMBL461542 IC50 155.0 nM
O=C(Nc1cc(F)cc(F)c1)c1cc(Cl)ccc1O CHEMBL2179174 IC50 155.0 nM
O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cc(Cl)ccc1O CHEMBL536151 IC50 156.0 nM
CC(=O)N(c1ccn2nccc2c1)c1cc(NC(=O)Cc2c(Cl)cccc2Cl)ccn1 CHEMBL5188664 IC50 157.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1Oc1cccc(N2CCOCC2=O)c1 CHEMBL4451946 IC50 163.0 nM
CC(=O)N(c1ccc2ncoc2c1)c1cc(NC(=O)Cc2ccccc2Cl)ccn1 CHEMBL5178725 IC50 168.0 nM
CC(=O)N(c1cc(NC(=O)Cc2c(Cl)cccc2Cl)ccn1)c1ccncc1F CHEMBL5204109 IC50 171.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccc(F)cc2Cl)ccc1OCC1CCOCC1 CHEMBL4443857 IC50 173.0 nM
Cn1cc(Oc2ccc(NC(=O)Cc3ccccc3Cl)cc2S(N)(=O)=O)cn1 CHEMBL4462109 IC50 185.0 nM
O=C(OCc1ccccc1)N1c2ccccc2Oc2ccccc21 CHEMBL2180137 IC50 189.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1Oc1cccnc1 CHEMBL4541425 IC50 193.0 nM
O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccc(Cl)cc1O CHEMBL2338696 IC50 209.0 nM
CC(C)(O)c1ccccc1Oc1ccc(NC(=O)Cc2ccccc2Cl)cc1S(N)(=O)=O CHEMBL4577125 IC50 242.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1OCC1COCCO1 CHEMBL4450002 IC50 258.0 nM
O=C1CC(=O)N(c2cccc(-c3noc(=S)[n-]3)c2)c2ccc3ccccc3c2N1 CHEMBL4462656 IC50 260.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccc(F)cc2)ccc1Oc1cccc(Cl)c1 CHEMBL4450779 IC50 269.0 nM
Cc1ccc(CC(=O)Nc2ccc(Oc3cccc(Cl)c3)c(S(N)(=O)=O)c2)cc1 CHEMBL4451276 IC50 317.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccc(Cl)cc2)ccc1Oc1cccc(Cl)c1 CHEMBL4444721 IC50 345.0 nM
O=C1CN=C(c2cccc(Br)c2)c2oc3ccccc3c2N1 CHEMBL2180179 IC50 348.0 nM
CC(C)(O)c1ccc(Oc2ccc(NC(=O)Cc3ccccc3Cl)cc2S(N)(=O)=O)cc1 CHEMBL4539332 IC50 376.0 nM
Cc1ccc(S(=O)(=O)N2c3ccccc3Oc3ccccc32)cc1 CHEMBL2180160 IC50 420.0 nM
O=C(Cc1ccccc1I)Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1 CHEMBL4464823 IC50 430.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1Oc1ccccn1 CHEMBL4533763 IC50 441.0 nM
CC(C)(O)c1cccc(Oc2ccc(NC(=O)Cc3ccccc3Cl)cc2S(N)(=O)=O)c1 CHEMBL4455317 IC50 474.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1OC(=O)c1ccc(-c2ccccc2)cc1 CHEMBL339386 EC50 490.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O CHEMBL14249 EC50 500.0 nM
CC(C)c1cc(Br)c(NC(=O)Nc2cccnc2)c(Br)c1 CHEMBL1532400 IC50 500.0 nM
O=C1CC(=O)N(c2ccnc(-c3noc(=S)[nH]3)c2)c2ccc3ccccc3c2N1 CHEMBL5179436 IC50 503.0 nM
O=C(Nc1cccc(C(F)(F)F)c1)c1cc(Cl)ccc1O CHEMBL589733 IC50 537.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2F)ccc1OCC1CCOCC1 CHEMBL4458990 IC50 597.0 nM
O=C(Nc1cc(Cl)cc(Cl)c1)c1cc(Cl)ccc1O CHEMBL2179173 IC50 712.0 nM
O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccc2ccccc2c1O CHEMBL2338686 IC50 729.0 nM
NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1OCC1CCO1 CHEMBL4456686 IC50 784.0 nM
O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL5202979 pIC50 891.25 nM
O=C(NC(=S)Nc1cccc2cccnc12)c1ccc2c(c1)OCO2 CHEMBL5178892 IC50 908.0 nM
O=C(NC(=S)Nc1cccnc1Cl)c1ccc2c(c1)OCO2 CHEMBL5205239 IC50 935.0 nM
CSc1nc(N)c2ncn([C@@H]3O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]3O)c2n1 CHEMBL336208 EC50 1000.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]2O[C@@H](n3cnc4c(N)ncnc43)[C@H](O)[C@@H]2O)[C@@H](O)[C@H]1O CHEMBL339385 EC50 1000.0 nM