O=c1c(O[C@H]2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2O)c(-c2ccc(O)cc2)oc2cc(O)cc(O)c12 CHEMBL1572115 AC50_uM 15.5 nM
Oc1cc2c(cc1C(c1ccc3c(c1)OCO3)N1CCCC1)OCO2 CHEMBL4748449 IC50 23.0 nM
O=C(C1CC1)N1CCN(Cn2sc3ccccc3c2=O)CC1 CHEMBL4637290 Kd 62.0 nM
Oc1cc2c(cc1C(Nc1ccccn1)c1ccc3c(c1)OCO3)OCO2 CHEMBL4786482 IC50 72.0 nM
Oc1cc2c(cc1C(c1ccc(Cl)cc1)N1CCOCC1)OCO2 CHEMBL1369923 IC50 92.0 nM
Oc1c(C(Nc2ccccc2)c2ccccc2)ccc2cccnc12 CHEMBL3741464 IC50 110.0 nM
COC(=O)c1cccc(/C=C/C(=O)c2cccc(O)c2)c1 CHEMBL4483086 IC50 120.0 nM
C[C@H](CO)N1C[C@H](C)[C@@H](CN(C)S(=O)(=O)c2ccccc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O CHEMBL1987920 AC50_uM 125.0 nM
COC(=O)c1cccc(/C=C/C(=O)c2ccc(CO)c(Br)c2)c1 CHEMBL4472710 IC50 130.0 nM
COc1ccc(C(c2cc3c(cc2O)OCO3)N2CCOCC2)cc1 CHEMBL1319324 IC50 130.0 nM
Cc1ccnc(NC(c2ccc(F)cc2)c2ccc3cccnc3c2O)c1 CHEMBL4740031 IC50 140.0 nM
COc1ccc(C(Nc2cc(C)ccn2)c2ccc3cccnc3c2O)cc1O CHEMBL3703646 IC50 150.0 nM
O=[N+]([O-])c1ccc(NC(c2ccccc2)c2ccc3cccnc3c2O)cc1 CHEMBL1688556 IC50 150.0 nM
CCCCCN(CCCCC)S(=O)(=O)c1ccc(C(=O)/C=C/c2cccc(C#N)c2)cc1 CHEMBL4459949 IC50 160.0 nM
COc1cc(C(Nc2ccccn2)c2cc3c(cc2O)OCO3)cc(OC)c1O CHEMBL4780610 IC50 170.0 nM
Oc1c(C(Nc2ccccn2)c2ccc(Cl)cc2)ccc2cccnc12 CHEMBL590899 IC50 170.0 nM
CCc1ccc(C(Nc2ccccn2)c2ccc3cccnc3c2O)cc1 CHEMBL591855 IC50 170.0 nM
COc1cc(C(c2cc3c(cc2O)OCO3)N2CCCC2)cc(OC)c1OC CHEMBL1557864 IC50 180.0 nM
COc1cc(C(Nc2ccc(C)cn2)c2ccc3cccnc3c2O)cc(OC)c1O CHEMBL4790355 IC50 180.0 nM
CCOC(=O)C1(CCOc2ccccc2)CCN(Cc2ccc(O)c(Cl)c2)CC1 CHEMBL1536119 IC50 190.0 nM
Cc1cc(C)c(C(Nc2ccccn2)c2ccc3cccnc3c2O)c(C)c1 CHEMBL600752 IC50 190.0 nM
O=C(/C=C/c1ccc(-c2ccncc2)cc1)c1cccc(O)c1 CHEMBL4446669 IC50 210.0 nM
N#Cc1ccc(/C=C/C(=O)c2ccc(O)c(F)c2)cc1 CHEMBL4550951 IC50 210.0 nM
O=C(/C=C/c1ccc(-n2cnc3ccccc32)cc1)c1cccc(O)c1 CHEMBL4472807 IC50 230.0 nM
COc1cc(C(c2cc3c(cc2O)OCO3)N2CCOCC2)ccc1O CHEMBL1554780 IC50 230.0 nM
Oc1cc2c(cc1C(c1ccc(F)cc1)N1CCOCC1)OCO2 CHEMBL2323557 IC50 230.0 nM
Oc1cc2c(cc1C(c1ccc(F)cc1)N1CCCCC1)OCO2 CHEMBL4799930 IC50 270.0 nM
Oc1c(C(c2ccc(F)cc2)N2CCCCC2)ccc2c1OCCO2 CHEMBL4782811 IC50 290.0 nM
Oc1ccc2[nH]ncc2c1C(c1ccc(-n2cccc2)cc1)N1CCCCC1 CHEMBL4763853 IC50 290.0 nM
COc1ccc(C(c2cc3c(cc2O)OCO3)N2CCOCC2)cc1OC CHEMBL1565145 IC50 300.0 nM
O=C(O)c1ccc(NC(c2ccccc2)c2ccc3cccnc3c2O)cc1 CHEMBL1979298 IC50 300.0 nM
Oc1c(C(c2ccc(C(F)(F)F)cc2)N2CCCCC2)ccc2ccoc12 CHEMBL4753733 IC50 300.0 nM
COc1ccccc1C(c1cc2c(cc1O)OCO2)N1CCOCC1 CHEMBL1485589 IC50 330.0 nM
Oc1ccccc1C(c1cc2c(cc1O)OCO2)N1CCOCC1 CHEMBL1360077 IC50 340.0 nM
Oc1ccc2[nH]ncc2c1C(c1ccc(-c2nccs2)cc1)N1CCCCC1 CHEMBL4764068 IC50 340.0 nM
O=C(/C=C/c1ccc(-c2cccnc2)cc1)c1cccc(O)c1 CHEMBL4464788 IC50 350.0 nM
Oc1cc2c(cc1C(c1ccc3c(c1)OCO3)N1CCCCC1)OCO2 CHEMBL1433812 IC50 350.0 nM
Cc1ccnc(NC(c2cccc(F)c2)c2ccc3cccnc3c2O)c1 CHEMBL4755661 IC50 350.0 nM
Oc1ccc2[nH]ncc2c1C(c1ccc(F)cc1)N1CCCCC1 CHEMBL4776190 IC50 350.0 nM
COc1ccc(C(c2cc3c(cc2O)OCO3)N2CCCC2)c(OC)c1 CHEMBL4745645 IC50 360.0 nM
Oc1cccc(C(Nc2ccccn2)c2ccc3cccnc3c2O)c1Cl CHEMBL1434798 IC50 370.0 nM
CCOC(=O)c1c(CNCCN(CC)CC)n(C)c2cc(Br)c(OC)cc12 CHEMBL1402451 AC50_uM 376.0 nM
COc1ccccc1NC(c1ccccc1)c1ccc2cccnc2c1O CHEMBL4756890 IC50 390.0 nM
COc1cccc(C(c2ccc3cccnc3c2O)N2CCOCC2)c1OC CHEMBL4747596 IC50 390.0 nM
COC(=O)c1cccc(/C=C/C(=O)c2ccc(O)cc2)c1 CHEMBL4520508 IC50 400.0 nM
O=C(/C=C/c1ccc(Br)cc1)c1cccc(O)c1 CHEMBL4567542 IC50 400.0 nM
Oc1c(C(c2ccc3c(c2)CCC3)N2CCCCC2)ccc2ccoc12 CHEMBL4785141 IC50 410.0 nM
CC(=O)O[C@@H]1O[C@H](CSC2=CC(=O)c3cccc(O)c3C2=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O CHEMBL5399770 IC50 420.0 nM
Cn1cnnc1Sc1ccc(/C=C/C(=O)c2ccc(O)cc2)cc1[N+](=O)[O-] CHEMBL1459949 AC50_uM 422.0 nM
Cc1ccc(C(Nc2ccccn2)c2ccc3cccnc3c2O)cc1 CHEMBL1497004 IC50 460.0 nM
CC(=O)OC[C@H]1O[C@@H](SC2=C(c3ccc(O)cc3O)C(=O)c3c(O)cccc3C2=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O CHEMBL5408166 IC50 460.0 nM
Oc1c(C(Nc2ccccn2)c2ccccc2F)ccc2cccnc12 CHEMBL1326401 IC50 470.0 nM
COc1ccc(SC2=C(c3ccc(O)cc3O)C(=O)c3c(O)cccc3C2=O)cc1 CHEMBL5404518 IC50 470.0 nM
COC(=O)c1cccc(/C=C/C(=O)c2ccc(O)c(C(F)(F)F)c2)c1 CHEMBL4520670 IC50 490.0 nM
Oc1c(C(Nc2ccccn2)c2ccccc2Cl)ccc2cccnc12 CHEMBL2094875 IC50 500.0 nM
COc1cccc(C(c2cc3c(cc2O)OC(F)(F)O3)N2CCOCC2)c1OC CHEMBL4791006 IC50 510.0 nM
O=[N+]([O-])c1ccc(C(c2c(O)ccc3[nH]ncc23)N2CCCCC2)cc1 CHEMBL4749715 IC50 520.0 nM
Cc1ccnc(NC(c2ccc([N+](=O)[O-])cc2)c2ccc3cccnc3c2O)c1 CHEMBL589706 IC50 530.0 nM
O=C1C=C(c2ccc(O)cc2O)C(=O)c2c(O)cccc21 CHEMBL5423893 IC50 530.0 nM
Oc1c(C(c2ccc(F)cc2)N2CCCCC2)ccc2ccoc12 CHEMBL4747039 IC50 560.0 nM
Oc1c(C(c2ccc(F)cc2)N2CCCCC2)ccc2scnc12 CHEMBL4777232 IC50 570.0 nM
CCOC(=O)c1c(CN2CCN(CCO)CC2)n(-c2ccccc2)c2cc(Br)c(O)cc12 CHEMBL1497214 AC50_uM 610.0 nM
Oc1c(C(c2ccc(F)cc2)N2CCCCC2)ccc2cnccc12 CHEMBL4758414 IC50 610.0 nM
COc1ccc(C(c2cc3c(cc2O)OCO3)n2ccnc2)cc1 CHEMBL522733 IC50 620.0 nM
Cc1ccnc(NC(c2ccc(OCc3ccccc3)cc2)c2ccc3cccnc3c2O)c1 CHEMBL4799197 IC50 620.0 nM
CC(=O)OC[C@H]1O[C@H](OC2=CC(=O)c3cccc(O)c3C2=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O CHEMBL5418475 IC50 620.0 nM
O=C1C=CC(=O)c2c(O)cccc21 CHEMBL43612 IC50 630.0 nM
COc1cc(C(c2cc3c(cc2O)OCO3)N2CCOCC2)cc(OC)c1OC CHEMBL1316752 IC50 640.0 nM
CC(C)(C)OC(=O)C1(CCOc2ccccc2)CCN(Cc2ccc(O)c(Cl)c2)CC1 CHEMBL3187354 IC50 650.0 nM
Oc1c(C(c2ccc(F)cc2)N2CCCCC2)ccc2nccnc12 CHEMBL4749634 IC50 660.0 nM
Oc1cc2c(cc1C(c1ccc(F)cc1)n1ccnc1)OCO2 CHEMBL513615 IC50 670.0 nM
Oc1cc2c(cc1C(c1ccc(F)cc1)N1CCCCC1)OCCO2 CHEMBL4785968 IC50 670.0 nM
Oc1ccc(C(c2cc3c(cc2O)OCO3)N2CCNCC2)cc1 CHEMBL4744354 IC50 680.0 nM
Oc1c(C(c2ccc(F)cc2)N2CCCCC2)ccc2cccnc12 CHEMBL4749576 IC50 690.0 nM
COc1cc(C(c2cc3c(cc2O)OCO3)N2CCCCC2)cc(OC)c1OC CHEMBL1570211 IC50 700.0 nM
Oc1ccc2[nH]ncc2c1C(c1ccc(C(F)(F)F)cc1)N1CCCCC1 CHEMBL4799492 IC50 710.0 nM
COc1cccc(SC2=CC(=O)c3cccc(O)c3C2=O)c1 CHEMBL5431799 IC50 710.0 nM
Cc1ccc(C)c(C(Nc2ccccn2)c2ccc3cccnc3c2O)c1 CHEMBL4797378 IC50 730.0 nM
N#Cc1ccc(/C=C/C(=O)c2ccc(O)cc2)cc1 CHEMBL4459634 IC50 740.0 nM
O=C1C=C(Sc2ccc(O)cc2)C(=O)c2c(O)cccc21 CHEMBL5425232 IC50 770.0 nM
COc1ccccc1SC1=CC(=O)c2cccc(O)c2C1=O CHEMBL5417462 IC50 790.0 nM
CCCCCN(CCCCC)S(=O)(=O)c1ccc(C(=O)/C=C/c2cccc(O)c2)cc1 CHEMBL4470548 IC50 810.0 nM
COc1ccc(C(=O)Nc2ccccc2C(=O)NCc2ccco2)cc1 CHEMBL1336749 AC50_uM 819.0 nM
CCCN(CCC)S(=O)(=O)c1ccc(C(=O)/C=C/c2cccc(C#N)c2)cc1 CHEMBL4447323 IC50 820.0 nM
N#Cc1cccc(/C=C/C(=O)c2ccc(B(O)O)cc2)c1 CHEMBL4513992 IC50 830.0 nM
Oc1ccc2[nH]ncc2c1C(c1ccc(-c2cncnc2)cc1)N1CCCCC1 CHEMBL4744038 IC50 830.0 nM
CC(C)OC(=O)C1(CCOc2ccccc2)CCN(Cc2ccc(O)c(Cl)c2)CC1 CHEMBL3186999 IC50 850.0 nM
N#Cc1cccc(/C=C/C(=O)c2ccc(O)cc2)c1 CHEMBL4545330 IC50 850.0 nM
COc1ccc(C(c2cc3c(cc2O)OCO3)N2CCCCC2)cc1 CHEMBL1490147 IC50 880.0 nM
Cc1ccnc(NC(c2ccccc2F)c2ccc3cccnc3c2O)c1 CHEMBL589912 IC50 880.0 nM
CCCCCSC1=CC(=O)c2cccc(O)c2C1=O CHEMBL5434284 IC50 880.0 nM
COc1cccc(C(c2cc3c(cc2O)OCO3)N2CCOCC2)c1O CHEMBL1476047 IC50 900.0 nM
COc1ccc(C(c2cc3c(cc2O)OCO3)N2CCCCC2)cc1OC CHEMBL1604428 IC50 960.0 nM
COc1cc(OC)c(C(c2cc3c(cc2O)OCO3)N2CCOCC2)c(OC)c1 CHEMBL1360494 IC50 980.0 nM