CC1NC(=O)[C@@H]2C[C@@]2(F)CCCC(F)(F)Cn2c(-c3nc4cc(C(=O)N5CCC[C@@H](N)[C@H]5C)cc(F)c4n3C3CC3)cc3ccc1nc32 CHEMBL5070220 IC50 5.0 nM
COc1cc(C(=O)N2C[C@H](N)[C@@H]3CC[C@H]2C3)cc2nc(-c3cc4ccc5nc4n3CCCCCC3[C@H](C(=O)NC5C)C3(F)F)n(C)c12 CHEMBL5083901 IC50 5.0 nM
[2H]C1([2H])[C@H](N)[C@@H]2CC[C@@H](C2)N1C(=O)c1cc(OC)c2c(c1)nc(-c1cc3ccc4nc3n1CCCCCc1ccccc1C(=O)NC4C)n2C CHEMBL5070080 IC50 5.0 nM
CC1NC(=O)c2cc3sccc3nc2CCCCCn2c(-c3nc4cc(C(=O)N5CCC[C@@H](N)[C@H]5C)cc(F)c4n3C3CC3)cc3ccc1nc32 CHEMBL5087104 IC50 5.0 nM
Cc1ccc2c(n1)CCCCCn1c(-c3nc4cc(C(=O)N5C[C@H](N)[C@@H]6CC[C@H]5C6)cc(F)c4n3C3CC3)cc3ccc(nc31)C(C)NC2=O CHEMBL5093574 IC50 6.0 nM
CC1NC(=O)[C@@H]2CC2CCCC(F)(F)Cn2c(-c3nc4cc(C(=O)N5CCC[C@@H](N)[C@H]5C)cc(Cl)c4n3C3CC3)cc3ccc1nc32 CHEMBL5080973 IC50 6.0 nM
COc1cc(C(=O)N2[C@H]3CC[C@@H]2[C@H](N)C3)cc2nc(-c3cc4ccc([C@@H](C)N5CCOC5=O)nc4n3CC3CC3)c(C)n12 CHEMBL5180282 IC50 14.1 nM
COc1cc(C(=O)N2[C@H]3CC[C@@H]2[C@H](N)C3)cc2nc(-c3cc4ccc([C@@H](C)NC(=O)N5CCO[C@@H](C)C5)nc4n3CC3CC3)c(C)n12 CHEMBL5187676 IC50 17.4 nM
COc1cc(C(=O)N2[C@H]3CC[C@@H]2[C@H](N)C3)cc2nc(-c3cc4ccc([C@@H](C)NC(=O)CCC(=O)O)nc4n3CC3CC3)c(C)n12 CHEMBL5201255 IC50 19.1 nM
COc1cc(C(=O)N2[C@H]3CC[C@@H]2[C@H](N)C3)cc2nc(-c3cc4ccc([C@@H](C)NC(=O)N(C)Cc5cccnc5)nc4n3CC3CC3)c(C)n12 CHEMBL5195279 IC50 20.0 nM
COc1cc(C(=O)N2[C@H]3CC[C@@H]2[C@H](N)C3)cc2nc(-c3cc4ccc([C@@H](C)NC(=O)CCC(=O)NS(=O)(=O)c5ccccc5)nc4n3CC3CC3)c(C)n12 CHEMBL5188806 IC50 20.3 nM
COc1cc(C(=O)N2[C@H]3CC[C@@H]2[C@H](N)C3)cc2nc(-c3cc4ccc(N5CCNCCS5(=O)=O)nc4n3CC3CC3)c(C)n12 CHEMBL5194669 IC50 21.6 nM
COc1cc(C(=O)N2CCC[C@@H](N)C2)cc2nc(-c3cc4ccccc4n3CC3CC3)n(C)c12 CHEMBL3944071 pIC50 39.81 nM
COc1cc(C(=O)N2CC[C@@H](O)[C@@H](N)C2)cc2nc(-c3cc4ccccc4n3CC3CC3)n(C)c12 CHEMBL4539512 IC50 50.0 nM
CCn1c(-c2nc3cc(C(=O)N4CCCC(N)C4)ccc3n2C)cc2ccccc21 CHEMBL5094982 IC50 50.0 nM
COc1cc(C(=O)N2CC[C@@H](O)[C@@H](N)C2)cc2nc(-c3cc4ccccc4n3CC3CC3)n(C)c12 CHEMBL5081624 IC50 50.0 nM
COc1cc(C(=O)N2CCC[C@@H](N)C2)cc2nc(-c3cc4ccccc4n3CC(F)(F)F)n(C)c12 CHEMBL3907951 pIC50 50.12 nM
COc1cc(C(=O)N2CC[C@@H](O)[C@@H](N)C2)cc2nc(-c3cc4ccccc4n3CC(F)(F)F)n(C)c12 CHEMBL3891031 pIC50 79.43 nM
CCn1c(-c2nc3cc(C(=O)N4CCC[C@@H](N)C4)cc(OC)c3n2C)cc2ccccc21 CHEMBL3939919 pIC50 100.0 nM
Cn1c(-c2cc3ccccc3n2CC2CC2)nc2cc(C(=O)N3CCC[C@@H](N)C3)ccc21 CHEMBL3981570 pIC50 125.89 nM
Cn1c(-c2cc3ccccc3n2CC(F)(F)F)nc2cc(C(=O)N3CCC[C@@H](N)C3)ccc21 CHEMBL3952821 pIC50 158.49 nM
COc1cc(C(=O)N2CCC[C@@H](N)C2)cc2cc(-c3cc4cccnc4n3C)n(N)c12 CHEMBL5434057 IC50 200.0 nM
NC1=CC(=O)c2ccc(-c3cccc(C(=O)O)n3)nc2C1=O CHEMBL58150 IC50 240.0 nM
CCn1c(-c2nc3cc(C(=O)N4CC[C]C(N)C4)ccc3n2C)cc2ccccc21 CHEMBL5071309 IC50 250.0 nM
N=C(CF)NCCC[C@H](NC(=O)c1ccccc1C(=O)O)C(N)=O CHEMBL1910970 IC50 400.0 nM
NC1=C(Br)C(=O)c2cccnc2C1=O CHEMBL3113470 IC50 560.0 nM
NC1=CC(=O)c2ccc(-c3ccccn3)nc2C1=O CHEMBL57818 IC50 640.0 nM
NC1=CC(=O)c2cccnc2C1=O CHEMBL60908 IC50 1000.0 nM
CN(C)c1ccc2cc(C(=O)N[C@@H](CCCNC(=N)CCl)C(=O)NCc3ccccc3)ccc2c1 CHEMBL3682418 IC50 1000.0 nM