O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCn2c(nnc2-c2ccc(Br)o2)C1 CHEMBL5402698 IC50 1.1 nM
O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCN(C(=O)C2CC2)CC1 CHEMBL521686 Kd(app) 5.8 nM
NCCOc1c(-c2ccc(Cl)c(Cl)c2)[nH]c(=O)c2cc(F)ccc12 CHEMBL3901209 Kd 10.0 nM
CC(C)(N)C(=O)N1CC2=NNC(=O)c3cccc4[nH]c(c2c34)C1 CHEMBL3970252 IC50 18.0 nM
NCCOc1c(-c2ccc(Br)cc2)[nH]c(=O)c2cc(F)ccc12 CHEMBL3952782 Kd 20.0 nM
N#Cc1cccc(-c2[nH]c(=O)c3cc(F)ccc3c2OCCN)c1 CHEMBL3911149 Kd 20.0 nM
NCCOc1c(-c2ccc(Br)cc2)[nH]c(=O)c2c(F)c(F)ccc12 CHEMBL3905973 Kd 20.0 nM
NCCOc1c(-c2ccc(F)c(F)c2)[nH]c(=O)c2cc(F)ccc12 CHEMBL3975515 Kd 20.0 nM
NCCOc1c(-c2ccc(N3CCCC3)c(Br)c2)[nH]c(=O)c2cc(F)ccc12 CHEMBL3969175 Kd 20.0 nM
NCCOc1c(-c2ccc3c(c2)OCCO3)[nH]c(=O)c2cc(F)ccc12 CHEMBL3939639 Kd 20.0 nM
Cn1ncnc1[C@H]1c2n[nH]c(=O)c3cc(F)cc(c23)N[C@@H]1c1ccc(F)cc1 CHEMBL3137320 Kd(app) 24.0 nM
CNCc1ccc(-c2[nH]c3cc(F)cc4c3c2CCNC4=O)cc1 CHEMBL1173055 IC50 28.0 nM
NCCOc1c(-c2ccc(Cl)cc2)[nH]c(=O)c2cc(F)ccc12 CHEMBL3976589 Kd 30.0 nM
Cc1cc(-c2[nH]c(=O)c3cc(F)ccc3c2OCCN)ccc1Cl CHEMBL3933136 Kd 34.0 nM
Cn1c2cc(F)cc(C(N)=O)c2c(=O)n1C1CCNCC1 CHEMBL3663649 Kd 40.0 nM
N#Cc1cccnc1N1CCN(C(=O)c2cccc(Cc3n[nH]c(=O)c4ccccc34)c2)CC1 CHEMBL3740104 IC50 46.0 nM
O=C1NCC2c3c(cccc31)CCN2C(=O)Cc1cccnc1 CHEMBL595018 IC50 50.0 nM
NC(=O)c1cc(F)cc2[nH]n(C3CCNCC3)c(=O)c12 CHEMBL3663648 Kd 50.0 nM
COc1ccc(-c2[nH]c(=O)c3cc(F)ccc3c2OCCN)cc1F CHEMBL3910271 Kd 50.0 nM
CCC(CC)N1CCN(C(=O)c2cc(Cn3c(=O)[n-]c(=O)c4ccccc43)ccc2F)CC1=O CHEMBL5403305 IC50 51.0 nM
Cn1ncnc1[C@@H]1c2n[nH]c(=O)c3cc(F)cc(c23)N[C@H]1c1ccc(F)cc1 CHEMBL3764816 IC50 62.8 nM
CC1CN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccccc34)ccc2F)Cc2nnc(C(F)(F)F)n21 CHEMBL3907010 IC50 66.9 nM
C[C@]12CCCN1CC1=NNC(=O)c3cc(F)cc4[nH]c2c1c34 CHEMBL4112930 IC50 68.0 nM
O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCCNCC1 CHEMBL380648 Kd 70.0 nM
O=C1NCC2c3c(cccc31)CCN2C(=O)CCc1cnccn1 CHEMBL609002 IC50 70.0 nM
NCCOc1c(-c2ccc(F)cc2)[nH]c(=O)c2cc(F)ccc12 CHEMBL3984540 Kd 70.0 nM
NCCOc1c(-c2ccc(N3CCOCC3)c(Br)c2)[nH]c(=O)c2cc(F)ccc12 CHEMBL3959475 Kd 90.0 nM
Cc1ccc2c(=O)[nH]c(-c3ccc(C(C)(C)O)cc3)cn12 CHEMBL5199558 IC50 110.0 nM
CC1(C)CC2=NNC(=O)c3cc(F)cc4[nH]c(c2c34)C1 CHEMBL3911687 IC50 136.0 nM
O=C1NN=C2CN(C(=O)C3CC3)Cc3[nH]c4cccc1c4c32 CHEMBL3922789 IC50 180.0 nM
O=C1NN=C2CCCc3[nH]c4cccc1c4c32 CHEMBL3891329 IC50 199.0 nM
C[C@]1(c2nc3c(C(N)=O)cccc3[nH]2)CCCN1 CHEMBL506871 Kd(app) 231.0 nM
Cn1c2cc(F)cc(C(N)=O)c2c(=O)n1C1CCN(C2CCCCC2)CC1 CHEMBL3663650 Kd 270.0 nM
NC(=O)c1cccc2cn(-c3ccc([C@@H]4CCCNC4)cc3)nc12 CHEMBL1094636 pIC50 295.12 nM
CC(C)(C)C(=O)N1CC2=NNC(=O)c3cccc4[nH]c(c2c34)C1 CHEMBL3978989 IC50 660.0 nM
CN(C)CC(=O)Nc1ccc2[nH]c(=O)c3ccccc3c2c1 CHEMBL372303 Kd 700.0 nM
CC(C)N1CC2=NNC(=O)c3cccc4[nH]c(c2c34)C1 CHEMBL3907535 IC50 760.0 nM
Oc1nc(-c2ccc(C(F)(F)F)cc2)nc2c1CSCC2 CHEMBL1086580 pIC50 831.76 nM
C[C@H](NC(=O)CCc1nc2ccccc2c(=O)[nH]1)c1ccccc1 CHEMBL3092537 IC50 900.0 nM
O=C(CCc1nc2ccccc2c(=O)[nH]1)N[C@H](CO)Cc1ccccc1 CHEMBL3092553 IC50 1000.0 nM
CC1(C)CC2=NNC(=O)c3cccc4c3c2c(n4CC2CO2)C1 CHEMBL3940569 IC50 1000.0 nM