C[C@H]1CN([C@@H](C)CO)S(=O)(=O)c2ccc(C#Cc3ccncc3)cc2O[C@@H]1CN(C)C(=O)Nc1ccc2c(c1)OCO2 CHEMBL2355724 AC50 264.0 nM
C=CCn1c(C)cc(C2=NN=C(NCC)SC2)c1C CHEMBL1573994 AC50 267.0 nM
CC(C)CCCCCCCCCCCCC(=O)NCC(=O)NC1C(C)OC(Nc2[nH]cnc3ncnc2-3)C(O)C1O CHEMBL1735419 AC50 275.0 nM
COc1cc(/C=N/NC(=O)c2ccc(CN3C(=O)c4cccc5cccc3c45)cc2)cc(OC)c1O CHEMBL2005533 AC50 286.0 nM
NC(=S)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12 CHEMBL171699 AC50 294.0 nM
CCOc1ccc(C2=Nn3c(nnc3-c3ccccc3OC)SC2)cc1 CHEMBL1342336 AC50 317.0 nM
COc1ccc(N(C(=O)CCl)C(C(=O)NCCc2ccccc2)c2cccs2)cc1Cl CHEMBL1499544 AC50 323.0 nM
O=C1NC2C(=CC(O)C(O)C2O)c2cc3c(cc21)OCO3 CHEMBL1728514 AC50 325.0 nM
CC(=O)O[C@H]1C[C@H](O[C@H]2[C@@H](O)C[C@H](O[C@H]3[C@@H](O)C[C@H](O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5CC[C@]5(C)[C@@H](C7=CC(=O)OC7)CC[C@]65O)C4)O[C@@H]3C)O[C@@H]2C)O[C@H](C)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O CHEMBL3391717 AC50 345.0 nM
COc1cc2c(c(OC)c1OC)-c1ccc(O)cc1[C@@H](NC(C)=O)CC2 CHEMBL486504 AC50 370.0 nM
COc1ccc(S(=O)(=O)Nc2ccc3c(c2)C(=O)N([C@@H](C)CO)C[C@H](C)[C@@H](CN(C)Cc2ccc(C(F)(F)F)cc2)OCCCC[C@H](C)O3)cc1 CHEMBL2358582 AC50 372.0 nM
COc1ccc(C)cc1NS(=O)(=O)c1ccc(-c2cnc(C3CC3)o2)cc1 CHEMBL1445297 AC50 376.0 nM
CN(C(=O)OC(C)(C)C)c1ccc(-c2nc3ccccc3s2)cc1 CHEMBL1301042 AC50 379.0 nM
C[C@H]1O[C@@H](O[C@H]2[C@@H](O)C[C@H](O[C@H]3[C@@H](O)C[C@H](O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5C[C@@H](O)[C@]5(C)[C@@H](C7=CC(=O)OC7)CC[C@]65O)C4)O[C@@H]3C)O[C@@H]2C)C[C@H](O)[C@@H]1O CHEMBL1751 AC50 414.0 nM
CCC(C)(O)C(=O)OC1C(=O)OC2CC3C(C)=CC(=O)C(O)C3(C)C3C4(O)OCC23C1C(C)C4O CHEMBL1728992 AC50 426.0 nM
CC(=O)Nc1ccc(S(=O)(=O)c2ccnc3cc(Cl)ccc23)cc1 CHEMBL1868520 AC50 449.0 nM
COC(=O)[C@H]1[C@@H](O)[C@@]2(O)c3c(OC)cc(OC)cc3O[C@@]2(c2ccc(OC)cc2)[C@@H]1c1ccc(F)cc1 CHEMBL2361658 AC50 465.0 nM
CC1OC(CC(=O)O)CC2=C1C(=O)c1c(O)cccc1C2=O CHEMBL1212972 AC50 469.0 nM
CN1c2ccc(-c3cccc(F)c3)cc2[C@@H]2[C@@H](CCN2C(=O)Cc2ccccc2)[C@@H]1CO CHEMBL2354622 AC50 479.0 nM
C[C@H]1CN([C@@H](C)CO)C(=O)CCCn2nncc2CO[C@@H]1CN(C)C(=O)Nc1ccc(-c2cccs2)cc1 CHEMBL2358770 AC50 480.0 nM
COc1ccc(C(C(=O)NC2CCCCC2)N(C(=O)CCl)c2ccc(C)cc2)cc1 CHEMBL1444020 AC50 533.0 nM
CSCCC(c1nnnn1Cc1ccccc1)N1CCC(n2c(O)nc3ccccc32)CC1 CHEMBL1901000 AC50 538.0 nM
CC(N)C(=O)NC1C2C(=C(O)OC1(C)C(Cl)Cl)C(=O)CC(O)C2O CHEMBL1700479 AC50 546.0 nM
COc1ccc(C[C@H](N)C(=O)N[C@H]2[C@@H](O)[C@H](n3cnc4c(N(C)C)ncnc43)O[C@@H]2CO)cc1 CHEMBL531268 AC50 546.0 nM
COc1cc(C2C(C#N)=C(N)Oc3cc4c(cc32)OCO4)cc(OC)c1OC CHEMBL1312935 AC50 553.0 nM
O=C(CCl)/N=c1\sccn1Cc1cccc2ccccc12 CHEMBL1973122 AC50 572.0 nM
CSc1ccc(COC(=O)c2cc([N+](=O)[O-])ccc2N2CCOCC2)cc1 CHEMBL1592124 AC50 619.0 nM
COc1cccc(/C=N/Nc2ccc(C(=O)O)cc2)c1O CHEMBL3199673 AC50 635.0 nM
COc1ccc(C2C(O)C(c3c[nH]c4ccccc34)=NN2C(=O)CCl)cc1 CHEMBL1366838 AC50 650.0 nM
COC1CC2C=C(C)C=CC=CC(=O)NC(c3ccccc3)CC=CCCC(O)CC(O)=C2C1=O CHEMBL1900870 AC50 673.0 nM
O=C(NC(Nc1nc2ccc([N+](=O)[O-])cc2s1)(C(F)(F)F)C(F)(F)F)c1ccccc1Cl CHEMBL1497549 AC50 676.0 nM
CCCCCCCn1c2c(c(=N)c3c1CCC3)CCCC2 CHEMBL536166 AC50 677.0 nM
O=C1c2c(O)ccc(O)c2C(=O)c2c(NCCNCCO)ccc(NCCNCCO)c21 CHEMBL1417019 AC50 690.0 nM
Cc1cc(Br)c(OCc2ccc(C(=O)N/N=C/c3ccc[nH]3)cc2)c(Br)c1 CHEMBL3191107 AC50 693.0 nM
COc1ccc(NC(=O)C(=O)NCC2CCCN2S(=O)(=O)c2ccc(C)cc2)cc1 CHEMBL1368103 AC50 709.0 nM
COc1cc(/C=N\NC(=O)c2ccc(-c3ccccc3)cc2)cc(OC)c1OC(C)=O CHEMBL3196760 AC50 728.0 nM
O=C(c1cc(-c2cccs2)on1)N1CCN(C(c2ccccc2)c2ccccc2)CC1 CHEMBL1347023 AC50 733.0 nM
C=C1C(=O)O[C@@H]2C[C@@H](C)[C@@H]3C=CC(=O)[C@@]3(C)[C@@H](OC(C)=O)[C@H]12 CHEMBL486196 AC50 742.0 nM
Cn1nnnc1Sc1ncnc2scc(-c3ccc4c(c3)OCO4)c12 CHEMBL1359120 AC50 747.0 nM
OCC1OC(n2cnc3c(NCc4ccccc4O)ncnc32)C(O)C1O CHEMBL1698341 AC50 759.0 nM
Cc1ccc(/C=N/NC(=O)COc2ccccc2-c2ccccc2)cc1 CHEMBL1997171 AC50 770.0 nM
OCC1OC(n2cnc3c(O)nnnc32)C(O)C1O CHEMBL1867000 AC50 785.0 nM
Cc1ccc(S(=O)(=O)N(C)C[C@@H]2Oc3ccc(NC(=O)Nc4ccc(C(F)(F)F)cc4)cc3CC(=O)N([C@@H](C)CO)C[C@@H]2C)cc1 CHEMBL2361755 AC50 799.0 nM
CC(=O)O[C@H]1C[C@H](O[C@H]2[C@@H](O)C[C@H](O[C@H]3[C@@H](O)C[C@H](O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5C[C@@H](O)[C@]5(C)[C@@H](C7=CC(=O)OC7)CC[C@]65O)C4)O[C@@H]3C)O[C@@H]2C)O[C@H](C)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O CHEMBL506569 AC50 801.0 nM
CO[C@H]1[C@@H](O)[C@@H](O)O[C@@H](O[C@H]2CC[C@@]3(C)[C@H](CC[C@@H]4[C@@H]3[C@H](O)C[C@]3(C)[C@@H](C5=CC(=O)OC5)CC[C@]43O)C2)[C@@H]1O CHEMBL3391720 AC50 809.0 nM
O=[N+]([O-])c1ccc(O)c(-c2cc(C(F)(F)F)nc(-c3ccccc3)n2)c1 CHEMBL589238 AC50 811.0 nM
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)CC(O)(C(=O)CO)CC3OC1CC(N(C)C)C(O)C(C)O1 CHEMBL1700268 AC50 833.0 nM
CCc1c2c(nc3ccc(OC(=O)N4CCC(N5CCCCC5)CC4)cc13)-c1cc3c(c(=O)n1C2)COC(=O)[C@]3(O)CC CHEMBL1200512 AC50 844.0 nM
CN1C2CCC1/C(=C/c1ccccn1)C(=O)/C2=C\c1ccccn1 CHEMBL1990598 AC50 852.0 nM
O=C1c2cccc3cc([N+](=O)[O-])cc(c23)C(=O)N1CCN1CCCC1 CHEMBL46874 AC50 870.0 nM
O=S(=O)(c1ccc2c(c1)C(=NO)c1cc(S(=O)(=O)N3CCCCC3)ccc1-2)N1CCCCC1 CHEMBL1349063 AC50 871.0 nM
O=C(Nc1cccc(C2=NCCN2)c1)Nc1cccc(C2=NCCN2)c1 CHEMBL1315701 AC50 879.0 nM
CN(C[C@H]1N[C@@H](CO)[C@@H]1c1ccc(C2=CCCC2)cc1)C(=O)c1ccc(F)cc1 CHEMBL2138714 AC50 895.0 nM
C[n+]1c2n(c3ccccc31)N=C(c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)CS2 CHEMBL1343490 AC50 906.0 nM
COc1cccc(N2CCN(C(=O)c3ccc(C[S+]([O-])c4ccccc4Cl)o3)CC2)c1 CHEMBL1321427 AC50 921.0 nM
C[C@H](CO)N1C[C@H](C)[C@H](CN(C)Cc2ccc(C(F)(F)F)cc2)OCCCC[C@H](C)Oc2ccc(NS(=O)(=O)c3ccccc3)cc2C1=O CHEMBL2356603 AC50 927.0 nM
Cc1ccc(C(=O)c2cc([N+](=O)[O-])ccc2N2CCCCC2)c(C)c1 CHEMBL1332565 AC50 929.0 nM
Cc1noc(/C=C/c2ccco2)c1S(=O)(=O)N1CCC(C(=O)NC(C)c2ccccc2)CC1 CHEMBL1386234 AC50 931.0 nM
COc1ccc(OC)c(N(CCN2C(=O)c3ccccc3C2=O)C(=O)CCl)c1 CHEMBL1904974 AC50 966.0 nM