Cc1cc(O)c(-c2ccc([C@@H](C)CN)cc2)c2c1[nH]c(=O)c1ccccc12 CHEMBL4445123 IC50 0.5 nM
Cc1ccc2c(=O)[nH]c3c(C)cc(O)c(-c4ccc([C@@H](C)N)cc4)c3c2c1 CHEMBL4452726 IC50 1.56 nM
Cc1cc(O)c(-c2ccc([C@@H](C)CN)cc2)c2c1[nH]c(=O)c1sccc12 CHEMBL3672295 IC50 2.6 nM
C[C@@H](N)c1ccc(-c2c(O)cc(Cl)c3[nH]c(=O)c4ccccc4c23)cc1 CHEMBL4440222 IC50 2.71 nM
Cc1cc(O)c(-c2ccc([C@@H](C)N)cc2)c2c1[nH]c(=O)c1ccccc12 CHEMBL4527920 IC50 2.94 nM
C[C@@H](CN)c1ccc(-c2c(O)cc(Cl)c3[nH]c(=O)c4ccccc4c23)cc1 CHEMBL4564624 IC50 4.59 nM
O=C(N[C@H]1CCCNC1)c1ccnc2nc(-c3ccc(N4CCNCC4)s3)[nH]c12 CHEMBL3715360 IC50 5.2 nM
NC12CC3CC(C1)CC(NC(=O)c1ccnc4[nH]c(C5CC5)nc14)(C3)C2 CHEMBL3716544 IC50 5.3 nM
COc1cc(C)c2[nH]c(=O)c3ccccc3c2c1-c1ccc([C@@H](C)CN)cc1 CHEMBL4536593 IC50 5.44 nM
Cc1ccc2c(=O)[nH]c3c(C)cc(O)c(-c4ccc([C@@H](C)CN)cc4)c3c2c1 CHEMBL4452595 IC50 6.44 nM
Cc1cccc(Nc2nc(NC3CCCCC3N)cnc2C(N)=O)c1 CHEMBL1974328 pKi 10.0 nM
Cc1cc(O)c(-c2ccc([C@@H](C)CN)cc2)c2c1[nH]c(=O)c1sccc12 CHEMBL4537262 IC50 10.69 nM
Cc1ccc2c(=O)[nH]c3c(C)cc(O)c(-c4ccc([C@@H](C)CN(C)C)cc4)c3c2c1 CHEMBL4469640 IC50 19.06 nM
Cc1ccc2c(=O)[nH]c3c(C)cc(O)c(-c4ccc([C@@H](C)N(C)C)cc4)c3c2c1 CHEMBL4455498 IC50 20.88 nM
FC(F)(F)c1n[nH]cc1-c1nc2ccc3[nH]ncc3c2c2c1CCCC2 CHEMBL4593398 IC50 21.0 nM
Cc1cc(O)c(-c2ccc([C@@H](C)N)cc2)c2c1[nH]c(=O)c1sccc12 CHEMBL3672271 IC50 23.0 nM
NC12CC3CC(C1)CC(NC(=O)c1ccnc4nc(-c5cccs5)[nH]c14)(C3)C2 CHEMBL3715388 IC50 24.0 nM
Cc1cc(O)c(-c2ccc(C3(CN)CC3)cc2)c2c1[nH]c(=O)c1ccccc12 CHEMBL4458265 IC50 25.1 nM
C[C@H](c1ccc(-c2c(O)cc(Cl)c3[nH]c(=O)c4ccccc4c23)cc1)N(C)C CHEMBL4438486 IC50 26.13 nM
Cc1cc(O)c(-c2ccc([C@@H](C)CN(C)C)cc2)c2c1[nH]c(=O)c1sccc12 CHEMBL3672369 IC50 28.0 nM
N[C@H]1CC[C@H](NC(=O)c2ccnc3[nH]c(C4CC4)nc23)CC1 CHEMBL3716635 IC50 33.0 nM
O=C(NC[C@@H]1CCCNC1)c1ccnc2[nH]c(C3CC3)nc12 CHEMBL3715121 IC50 34.0 nM
O=C(N[C@H]1CCCNC1)c1ccnc2[nH]c(C3CC3)nc12 CHEMBL3718105 IC50 34.0 nM
NC1CCCC(NC(=O)c2ccnc3nc(-c4cccs4)[nH]c23)C1 CHEMBL3718439 IC50 35.0 nM
O=C(N[C@H]1CCCNC1)c1ccnc2nc(CC3CC3)[nH]c12 CHEMBL3715494 IC50 36.0 nM
O=C(NC[C@@H]1CCCNC1)c1ccnc2[nH]c(-c3cccs3)nc12 CHEMBL3718039 IC50 39.0 nM
Cc1cc(O)c(-c2ccc([C@@H](C)N(C)C)cc2)c2c1[nH]c(=O)c1ccccc12 CHEMBL4451419 IC50 44.89 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 54.3 nM
NC[C@H]1CC[C@H](NC(=O)c2ccnc3[nH]c(C4CC4)nc23)CC1 CHEMBL3718730 IC50 55.0 nM
O=C(N[C@H]1CCCNC1)c1ccnc2nc(Cc3cccs3)[nH]c12 CHEMBL3717059 IC50 59.0 nM
Cc1cc(O)c(-c2ccc([C@@H](C)N)cc2)c2c1[nH]c(=O)c1c(F)cccc12 CHEMBL4473141 IC50 61.41 nM
N[C@@H]1CCN(c2ccc(-c3nc4nccc(C(=O)N[C@H]5CCCNC5)c4[nH]3)s2)C1 CHEMBL3717532 IC50 63.0 nM
NCC1CCCC(CNC(=O)c2ccnc3[nH]c(-c4cccs4)nc23)C1 CHEMBL3718268 IC50 63.0 nM
Cc1cc(O)c(-c2ccc([C@@H](C)CN(C)C)cc2)c2c1[nH]c(=O)c1ccccc12 CHEMBL4444190 IC50 63.83 nM
Cc1cc(O)c(-c2ccc([C@@H](C)CN)cc2)c2c1[nH]c(=O)c1c(F)cccc12 CHEMBL4534841 IC50 64.46 nM
C[C@@H](CN(C)C)c1ccc(-c2c(O)cc(Cl)c3[nH]c(=O)c4ccccc4c23)cc1 CHEMBL4534499 IC50 65.0 nM
N[C@H]1CC[C@@H](CNC(=O)c2ccnc3nc(-c4cccs4)[nH]c23)CC1 CHEMBL3715032 IC50 72.0 nM
O=C(NCC1CCCNC1)c1ccnc2[nH]c(-c3cccs3)nc12 CHEMBL3715508 IC50 74.0 nM
O=C(N[C@H]1CCCNC1)c1ccnc2nc(-c3cccs3)[nH]c12 CHEMBL3717297 IC50 78.0 nM
O=C(N[C@H]1CCCNC1)c1ccc(O)c2[nH]c(-c3cccs3)nc12 CHEMBL3717841 IC50 86.0 nM
O=C(NC[C@H]1CCCNC1)c1ccnc2nc(Cc3cccs3)[nH]c12 CHEMBL3718758 IC50 98.0 nM
O=C(NC[C@H]1CCCNC1)c1ccnc2nc(-c3cccs3)[nH]c12 CHEMBL3715825 IC50 99.0 nM
O=C(N[C@H]1CCCNC1)c1ccnc2nc(-c3ccc(N4CCC(O)C4)s3)[nH]c12 CHEMBL3719067 IC50 110.0 nM
COc1cc(C=C2SC(=S)NC2=O)ccc1O CHEMBL1973098 pKi 125.89 nM
NC[C@H]1CC[C@H](NC(=O)c2ccnc3[nH]c(-c4cccs4)nc23)CC1 CHEMBL3717063 IC50 140.0 nM
COc1cc(C)c2[nH]c(=O)c3ccccc3c2c1-c1ccc([C@@H](C)N)cc1 CHEMBL4552688 IC50 142.5 nM
Cc1cc(O)c(-c2ccc(C3(CN(C)C)CC3)cc2)c2c1[nH]c(=O)c1ccccc12 CHEMBL4455728 IC50 143.9 nM
CN(CCO)c1ccc(-c2nc3c(C(=O)N[C@H]4CCCNC4)ccnc3[nH]2)s1 CHEMBL3718368 IC50 150.0 nM
O=C(NC1CCCNC1)c1ccnc2nc(-c3cccs3)[nH]c12 CHEMBL3716639 IC50 160.0 nM
O=C(NC1CCCNC1)c1ccc(O)c2[nH]c(-c3cccs3)nc12 CHEMBL3718662 IC50 180.0 nM
O=C(N[C@H]1CCCNC1)c1ccnc2nc(C3CC4CCC3C4)[nH]c12 CHEMBL3717470 IC50 180.0 nM
NC12CC3CC(C1)CC(NC(=O)c1ccc(O)c4[nH]c(-c5cccs5)nc14)(C3)C2 CHEMBL3717479 IC50 190.0 nM
O=C(NNC(=S)Nc1ccc(Cl)cc1)C(O)(c1ccccc1)c1ccccc1 CHEMBL1966722 pKi 199.53 nM
O=C(N[C@H]1CCCNC1)c1ccc(O)c2[nH]c(C3CC3)nc12 CHEMBL3715740 IC50 200.0 nM
O=C(NCC1CCCNC1)c1ccc(O)c2[nH]c(-c3cccs3)nc12 CHEMBL3717226 IC50 200.0 nM
O=C(N[C@H]1CCCNC1)c1ccnc2nc(-c3cc(N4CCNCC4)cs3)[nH]c12 CHEMBL3718956 IC50 220.0 nM
Cc1ccc2c(c1)c(=O)[nH]c1c(C)cc(O)c(-c3ccc([C@@H](C)CN)cc3)c12 CHEMBL4591205 IC50 223.7 nM
Cc1c(-c2ccc3[nH]nc(N)c3c2)nnn1Cc1ccccc1 CHEMBL1989646 pKi 251.19 nM
O=C(N[C@H]1CCCNC1)c1ccc(O)c2[nH]c(C3CCCC3)nc12 CHEMBL3716964 IC50 270.0 nM
O=C(NC[C@@H]1CCCNC1)c1ccnc2nc(-c3ccc(Br)o3)[nH]c12 CHEMBL3717200 IC50 290.0 nM
O=C(N[C@H]1CCCNC1)c1ccc(O)c2[nH]c(-c3ccccc3)nc12 CHEMBL3714837 IC50 300.0 nM
N[C@H]1CC[C@H](NC(=O)c2ccnc3nc(-c4cccs4)[nH]c23)CC1 CHEMBL3715412 IC50 300.0 nM
O=c1[nH]cnc2c1sc1c(Cl)ccc(Cl)c12 CHEMBL583144 Ki 316.1 nM
O=c1[nH]c2cc(Cl)cc(Cl)c2c(-c2cc(Cl)ccc2O)c1O CHEMBL1974803 pKi 316.23 nM
CC(C)(CO)CNc1nccc(-c2c(-c3ccc(F)cc3)nc3c(CC4CC4)nccn23)n1 CHEMBL1991800 pKi 316.23 nM
C[C@@H](CN)c1ccc(-c2c(O)cc(Cl)c3[nH]c(=O)c4c(O)cccc4c23)cc1 CHEMBL4579248 IC50 321.3 nM
NC[C@H]1CC[C@H](CNC(=O)c2ccnc3nc(-c4cccs4)[nH]c23)CC1 CHEMBL3717174 IC50 330.0 nM
Cc1cc(O)c(-c2ccc([C@@H](C)CN)cc2)c2c1[nH]c(=O)c1c(O)cccc12 CHEMBL4436998 IC50 335.7 nM
O=C(N[C@H]1CCCNC1)c1ccnc2nc(-c3ccc(N4CCOCC4)s3)[nH]c12 CHEMBL3718783 IC50 340.0 nM
CC1(C)CC(NC(=O)c2ccnc3nc(-c4cccs4)[nH]c23)CC(C)(CN)C1 CHEMBL3715259 IC50 340.0 nM
NC(=O)c1sc2ccc(Cl)c(Cl)c2c1NC(=O)c1ccc(Cl)cc1 CHEMBL2003271 pKi 398.11 nM
CC(C)Cc1cc(-c2ccc3[nH]nc(N)c3c2)on1 CHEMBL1966343 pKi 398.11 nM
Cc1cc(Cl)ccc1NC(=S)NNC(=O)C(O)(c1ccccc1)c1ccccc1 CHEMBL1988173 pKi 398.11 nM
NC(=O)c1cccc2[nH]c(-c3ccncc3)nc12 CHEMBL1990482 pKi 398.11 nM
O=C(Nc1cnccn1)Nc1ccnc2ccc(C(F)(F)F)cc12 CHEMBL1976455 pKi 398.11 nM
O=C(NC1CCCNC1)c1ccc(O)c2[nH]c(C3CC3)nc12 CHEMBL3714883 IC50 410.0 nM
O=C(NCC1CNC1)c1ccnc2nc(-c3cccs3)[nH]c12 CHEMBL3718661 IC50 410.0 nM
O=C(NC[C@@H]1CCCNC1)c1ccnc2nc(Cc3cccs3)[nH]c12 CHEMBL3718423 IC50 430.0 nM
O=C(N[C@H]1CCCNC1)c1ccc(O)c2[nH]c(C3CC4CCC3C4)nc12 CHEMBL3717192 IC50 450.0 nM
O=C(NC1CCNC1)c1ccnc2nc(-c3cccs3)[nH]c12 CHEMBL3718636 IC50 450.0 nM
O=C(N[C@H]1CCCNC1)c1ccnc2nc(-c3ccc(N4CCCCC4)s3)[nH]c12 CHEMBL3718407 IC50 460.0 nM
CC(C)(C)OC(=O)NC[C@H]1CC[C@H](NC(=O)c2ccnc3nc(C4CC4)[nH]c23)CC1 CHEMBL3716143 IC50 460.0 nM
NC[C@H]1CC[C@H](CNC(=O)c2ccnc3nc(C4CC5CCC4C5)[nH]c23)CC1 CHEMBL3718575 IC50 490.0 nM
NC12CC3CC(C1)CC(NC(=O)c1ccc(O)c4[nH]c(C5CC6CCC5C6)nc14)(C3)C2 CHEMBL3716414 IC50 500.0 nM
O=C(N[C@H]1CCCNC1)c1ccc(O)c2[nH]c(Cc3cccs3)nc12 CHEMBL3718881 IC50 500.0 nM
CC(=O)Nc1c(C(N)=O)sc2ccc(Cl)c(Cl)c12 CHEMBL1973142 pKi 501.19 nM
Cc1ccc(C(=O)Nc2c(C(N)=O)sc3ccc(Cl)c(Cl)c23)cc1 CHEMBL1965131 pKi 501.19 nM
O=C1NCCc2[nH]c(-c3ccncc3)cc21 CHEMBL225519 pKi 501.19 nM
NC(COc1cncc(C=Cc2ccncc2)c1)Cc1c[nH]c2ccccc12 CHEMBL1974935 pKi 501.19 nM
NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 CHEMBL2001751 pKi 501.19 nM
N[C@H]1CC[C@H](NC(=O)c2ccc(O)c3[nH]c(-c4cccs4)nc23)CC1 CHEMBL3717281 IC50 520.0 nM
O=C(NC[C@H]1CCCNC1)c1ccc(O)c2[nH]c(Cc3cccs3)nc12 CHEMBL3717466 IC50 550.0 nM
NC1CCCC(NC(=O)c2ccc(O)c3[nH]c(C4CC5CCC4C5)nc23)C1 CHEMBL3718588 IC50 570.0 nM
Cc1cc(O)c(-c2ccc([C@@H](C)CN)cc2)c2c1[nH]c(=O)c1c(C)cccc12 CHEMBL4458873 IC50 586.1 nM
O=C(NCC1CCCNC1)c1ccc(O)c2[nH]c(C3CCCC3)nc12 CHEMBL3715542 IC50 590.0 nM
O=C(NCC[C@@H]1CCCNC1)c1ccnc2nc(-c3cccs3)[nH]c12 CHEMBL3717030 IC50 590.0 nM
O=C(NCC1CCCCN1)c1ccc(O)c2[nH]c(C3CC3)nc12 CHEMBL3716223 IC50 620.0 nM
O=C(NCC1CCCCN1)c1ccc(O)c2[nH]c(-c3cccs3)nc12 CHEMBL3716979 IC50 620.0 nM
O=C(NCC1CCNC1)c1ccc(O)c2[nH]c(-c3cccs3)nc12 CHEMBL3715171 IC50 630.0 nM
O=C(N[C@H]1CCCNC1)c1ccnc2nc(-c3ccc(N4CCCC(O)C4)s3)[nH]c12 CHEMBL3715533 IC50 630.0 nM
NC1CCC(Nc2nccc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1966628 pKi 630.96 nM
NC1CCCCC1Nc1nccc(-c2c[nH]c3ncccc23)n1 CHEMBL1995813 pKi 630.96 nM
CCn1c(C)c(-c2ccnc(Nc3cccc(OC)c3)n2)sc1=O CHEMBL1986263 pKi 630.96 nM
NC(=O)c1cc2c(-c3ccc(F)cc3)cncc2s1 CHEMBL1974310 pKi 630.96 nM
NC(=O)c1ccc(-c2c[nH]c3nccc(Cl)c23)cc1 CHEMBL1982711 pKi 630.96 nM
C[C@@H](N)c1ccc(-c2c(O)cc(Cl)c3[nH]c(=O)c4c(O)cccc4c23)cc1 CHEMBL4535216 IC50 642.9 nM
O=C(NC[C@@H]1CCCNC1)c1ccc(O)c2[nH]c(Cc3cccs3)nc12 CHEMBL3719247 IC50 690.0 nM
O=C(c1nc2nccc(C(=O)N[C@H]3CCCNC3)c2[nH]1)c1cccs1 CHEMBL3716309 IC50 700.0 nM
Cc1cc(O)c(-c2ccc([C@@H](C)N)cc2)c2c1[nH]c(=O)c1c(C)cccc12 CHEMBL4535960 IC50 721.4 nM
O=C(NC1CCNC1)c1ccc(O)c2[nH]c(-c3cccs3)nc12 CHEMBL3716966 IC50 730.0 nM
O=C(NCC1CCCCN1)c1ccnc2nc(-c3cccs3)[nH]c12 CHEMBL3716727 IC50 740.0 nM
O=C(N[C@H]1CCCNC1)c1ccc(O)c2[nH]c(-c3ccc(Br)s3)nc12 CHEMBL3718848 IC50 770.0 nM
NC(=O)c1sc2c(Br)ccc(Cl)c2c1N CHEMBL1998611 pKi 794.33 nM
COc1cc(-c2ccc3c(c2)Nc2ccc(C(=O)NCc4cccc(F)c4)cc2NC3=O)ccc1O CHEMBL2000832 pKi 794.33 nM
O=c1[nH]c2cnc(-n3cnc4ccc(F)cc43)nc2n1C1CCOc2c(F)cccc21 CHEMBL2000393 pKi 794.33 nM
O=C(NC1CCCNC1)c1ccc(O)c2[nH]c(C3CC4CCC3C4)nc12 CHEMBL3717110 IC50 850.0 nM
Cc1ccc2c(c1)c(=O)[nH]c1c(C)cc(O)c(-c3ccc([C@@H](C)N)cc3)c12 CHEMBL4467180 IC50 894.3 nM
O=C(NCC1CCCNC1)c1ccc(O)c2[nH]c(-c3ccccc3)nc12 CHEMBL3714949 IC50 910.0 nM
O=C(NCC1CNC1)c1ccc(O)c2[nH]c(-c3cccs3)nc12 CHEMBL3719153 IC50 970.0 nM
Cc1cc(O)c(-c2ccc([C@@H](C)N)cc2)c2c1[nH]c(=O)c1c(O)cccc12 CHEMBL4474776 IC50 977.5 nM
Oc1c2ccccc2c2c3c(cccc13)N=N2 CHEMBL1725279 pKi 1000.0 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4c[nH]c5ccccc45)c3)cc12 CHEMBL1970903 pKi 1000.0 nM
O=C(N[C@H]1CCCNC1)c1ccnc2nc(-c3ccc(Br)s3)[nH]c12 CHEMBL3716044 IC50 1000.0 nM
O=C(NCC[C@H]1CCCNC1)c1ccnc2nc(-c3cccs3)[nH]c12 CHEMBL3717765 IC50 1000.0 nM