C[C@H]1CCCCN1c1cc(-c2ccccc2O)nnc1N CHEMBL5428009 Kd 5.0 nM
Nc1nnc(-c2ccccc2O)cc1N1CCCC1 CHEMBL5415064 Kd 6.0 nM
CC(C)[C@H]1CCCN1c1cc(-c2ccccc2O)nnc1N CHEMBL5409404 Kd 6.0 nM
Nc1nnc(-c2ccccc2O)cc1-c1ccccc1 CHEMBL5177096 IC50 8.9 nM
C[C@H]1CN(C(=O)OC(C)(C)C)CCN1c1cc(-c2ccccc2O)nnc1N CHEMBL5412292 Kd 9.0 nM
CC[C@H]1CCCN1c1cc(-c2ccccc2O)nnc1N CHEMBL5406315 Kd 9.0 nM
Nc1nnc(-c2ccccc2O)cc1N1CCCCC1 CHEMBL5424811 Kd 10.0 nM
CC(C)(C)OC(=O)N1CCN(c2cc(-c3ccccc3O)nnc2N)CC1 CHEMBL4780617 Kd 13.0 nM
C[C@H]1CCCN1c1cc(-c2ccccc2O)nnc1N CHEMBL5401472 Kd 15.0 nM
Nc1nnc(-c2ccccc2O)cc1N1CCC[C@@H]1C1CC1 CHEMBL5431862 Kd 15.0 nM
CC(=O)N1CCN(c2cc(-c3ccccc3O)nnc2N)C[C@H]1C CHEMBL5207330 Kd 18.0 nM
O=C(/C=C/N1C[C@H]2C[C@@H]1CN2c1ccccn1)c1ccccc1O CHEMBL3752911 Kd 25.0 nM
Nc1nnc(-c2ccccc2O)cc1N1CCNCC1 CHEMBL4746865 Kd 26.0 nM
O=C(/C=C/N1CCc2c(ncnc2NC2CC2)C1)c1ccccc1O CHEMBL3819245 Kd 28.0 nM
CC(=O)N1CCN(c2cc(-c3ccccc3O)nnc2N)[C@@H](C)C1 CHEMBL5398829 Kd 29.0 nM
C[C@@H]1CCCCN1c1cc(-c2ccccc2O)nnc1N CHEMBL5411199 Kd 40.0 nM
O=C(/C=C/N1CC2CC1CN2c1ccccn1)c1ccccc1O CHEMBL3899245 Kd 43.0 nM
C[C@@H]1CCCN1c1cc(-c2ccccc2O)nnc1N CHEMBL5425250 Kd 53.0 nM
Nc1nnc(-c2ccccc2O)cc1N1CCC(O)CC1 CHEMBL4793170 Kd 64.0 nM
CN1CCN(/C=C2\CCn3c2nc(=O)c2c(Cl)cccc23)CC1 CHEMBL3822689 Kd 124.0 nM
O=c1nc2n(c3cccc(Cl)c13)CC/C2=C\N1CCCCC1 CHEMBL3823524 Kd 127.0 nM
CN(C)/C=C1\CCn2c1nc(=O)c1c(Cl)cccc12 CHEMBL3823132 Kd 137.0 nM
C[C@H]1CCCCN1c1cc(-c2ccco2)nnc1N CHEMBL5426305 Kd 140.0 nM
CCN1CCN(/C=C2\CCn3c2nc(=O)c2c(Cl)cccc23)CC1 CHEMBL3824067 Kd 142.0 nM
Cc1cccc(C2NC(=O)c3c(Br)cccc3N2)c1 CHEMBL5180611 IC50 160.0 nM
CCC(/C=C1\CCn2c1nc(=O)c1c(Cl)cccc12)CC CHEMBL3823055 Kd 170.0 nM
Nc1nnc2c([nH]c3ccccc32)c1-c1ccccc1 CHEMBL5183240 Kd 170.0 nM
Cc1ccccc1C1NC(=O)c2c(Cl)cccc2N1 CHEMBL5195502 IC50 200.0 nM
Cc1cccc(C2NC(=O)c3c(Cl)cccc3N2)c1C CHEMBL5187356 IC50 220.0 nM
Nc1nnc(-c2ccccc2O)cc1N1CCC[C@@H](O)C1 CHEMBL4790365 Kd 238.0 nM
Cc1cccc(C2NC(=O)c3c(Cl)cccc3N2)c1 CHEMBL5170275 IC50 260.0 nM
C[C@H]1CCCN1c1cc(-c2ccco2)nnc1N CHEMBL5421138 Kd 280.0 nM
Cc1cccc(C)c1C1NC(=O)c2c(Cl)cccc2N1 CHEMBL5207236 IC50 290.0 nM
Cc1ccccc1C1NC(=O)c2c(Br)cccc2N1 CHEMBL5184118 IC50 290.0 nM
Nc1nnc(-c2ccccc2O)cc1N1CC[C@@H](O)[C@@H](O)C1 CHEMBL4788561 Kd 420.0 nM
Cc1ccc(C)c(C2NC(=O)c3c(Cl)cccc3N2)c1 CHEMBL5185774 IC50 430.0 nM
CC[C@H]1CCCN1c1cc(-c2ccco2)nnc1N CHEMBL5441040 Kd 440.0 nM
Nc1nnc(-c2ccco2)cc1N1CCC[C@@H]1C1CC1 CHEMBL5415253 Kd 560.0 nM
CC(C)[C@H]1CCCN1c1cc(-c2ccco2)nnc1N CHEMBL5415396 Kd 600.0 nM
CC(=O)N1c2ccc(-c3ccc(C(=O)O)cc3)cc2[C@H](Nc2ccc(Cl)cc2)C[C@@H]1C CHEMBL2177300 pIC50 630.96 nM
C[C@H]1CCCN1c1cc(-c2cccs2)nnc1N CHEMBL5394310 Kd 800.0 nM
C[C@@H]1CCCCN1c1cc(-c2ccco2)nnc1N CHEMBL5415837 Kd 800.0 nM
Cc1ccc(C2NC(=O)c3c(Cl)cccc3N2)c(C)c1 CHEMBL5195542 IC50 860.0 nM
Cc1ccc(C2NC(=O)c3c(Cl)cccc3N2)cc1 CHEMBL5194300 IC50 870.0 nM
Nc1nnc(-c2ccccc2O)cc1N1CC[C@H](O)[C@@H](O)C1 CHEMBL4742007 Kd 892.0 nM
Nc1nnc(-c2ccccc2O)cc1N1CCC[C@@H](Oc2ccccc2)C1 CHEMBL4753080 Kd 911.0 nM
O=C1NC(c2c(F)cccc2Cl)Nc2cccc(Cl)c21 CHEMBL5204703 IC50 1000.0 nM