O=c1cc(Nc2ccccc2)n(-c2ccccc2)c2nc(N3CCOCC3)cc(C(F)(F)F)c12 CHEMBL5437525 IC50 0.7 nM
Cn1ccnc1CCN1CC[C@@H](N2CC(=O)N3[C@H](c4ccc5c(c4)OCO5)c4[nH]c5ccccc5c4C[C@@H]3C2=O)C1 CHEMBL282515 IC50 1.4 nM
O=C1[C@H]2Cc3c([nH]c4ccccc34)[C@@H](c3ccc4c(c3)OCO4)N2C(=O)CN1[C@@H]1CCN(CCc2ccccn2)C1 CHEMBL284070 IC50 2.01 nM
O=C1[C@H]2Cc3c([nH]c4ccccc34)[C@@H](c3ccc4c(c3)OCO4)N2C(=O)CN1[C@@H]1CCN(CCc2cccnc2)C1 CHEMBL33518 IC50 2.4 nM
CCc1ccc([C@@H]2c3[nH]c4ccccc4c(=O)c3CN2c2ncc(-c3ccccn3)cn2)s1 CHEMBL4217054 IC50 2.7 nM
O=C1[C@H]2Cc3c([nH]c4ccccc34)[C@@H](c3ccc4c(c3)OCO4)N2C(=O)CN1[C@@H]1CCN(CCc2ncc[nH]2)C1 CHEMBL418594 IC50 3.5 nM
CCN1C(=O)[C@@H]2Cc3c([nH]c4ccccc34)[C@@H](c3ccc(C)o3)N2C1=O CHEMBL4292389 IC50 4.0 nM
O=C1[C@H]2Cc3c([nH]c4ccccc34)[C@@H](c3ccc4c(c3)OCO4)N2C(=O)CN1[C@@H]1CCN(CCc2cnccn2)C1 CHEMBL33121 IC50 4.2 nM
CCNC(=O)CCN1CC[C@@H](N2CC(=O)N3[C@H](c4ccc5c(c4)OCO5)c4[nH]c5ccccc5c4C[C@@H]3C2=O)C1 CHEMBL285737 IC50 4.3 nM
O=C(CCN1CC[C@@H](N2CC(=O)N3[C@H](c4ccc5c(c4)OCO5)c4[nH]c5ccccc5c4C[C@@H]3C2=O)C1)N1CCC1 CHEMBL286309 IC50 4.7 nM
CN(C)C(=O)CCN1CC[C@@H](N2CC(=O)N3[C@H](c4ccc5c(c4)OCO5)c4[nH]c5ccccc5c4C[C@@H]3C2=O)C1 CHEMBL33627 IC50 4.7 nM
CCc1ccc([C@@H]2c3[nH]c4ccccc4c(=O)c3CN2c2ncc(-c3ccccn3)cn2)o1 CHEMBL4217579 IC50 5.1 nM
O=C1[C@H]2Cc3c([nH]c4ccccc34)[C@@H](c3ccc4c(c3)OCO4)N2C(=O)CN1[C@@H]1CCN(Cc2ccccc2)C1 CHEMBL32255 IC50 5.5 nM
Cc1ccc([C@@H]2c3[nH]c4ccccc4c3C[C@@H]3C(=O)N([C@@H]4CCN(Cc5ccccc5)C4)CC(=O)N23)cc1 CHEMBL34744 IC50 6.5 nM
COc1ccc([C@@H]2c3[nH]c4ccccc4c3C[C@@H]3C(=O)N([C@@H]4CCN(Cc5ccccc5)C4)CC(=O)N23)cc1 CHEMBL34276 IC50 6.7 nM
CN1CC(=O)N2[C@H](c3ccc4c(c3)OCO4)c3[nH]c4ccccc4c3C[C@@H]2C1=O CHEMBL779 IC50 10.0 nM
CCN1CC(=O)N2[C@H](c3ccc(Cl)cc3Cl)c3[nH]c4ccccc4c3C[C@@H]2C1=O CHEMBL1650866 IC50 11.0 nM
COc1cccc([C@@H]2c3[nH]c4ccccc4c3C[C@@H]3C(=O)N([C@@H]4CCN(Cc5ccccc5)C4)CC(=O)N23)c1 CHEMBL284560 IC50 11.8 nM
CCN(CC)C(=O)c1cc(-c2ccnn2C)nc2c1c(C(F)F)nn2-c1ccccc1 CHEMBL5432407 IC50 12.0 nM
[2H]C([2H])([2H])C([2H])([2H])N(C(=O)c1cc(-c2ccnn2C)nc2c1c(C(F)F)nn2-c1ccccc1)C([2H])([2H])C([2H])([2H])[2H] CHEMBL5408783 IC50 16.0 nM
COCCCN1CC[C@@H](N2CC(=O)N3[C@H](c4ccc5c(c4)OCO5)c4[nH]c5ccccc5c4C[C@@H]3C2=O)C1 CHEMBL34802 IC50 22.0 nM
CCCCCN1CC[C@@H](N2CC(=O)N3[C@H](c4ccc5c(c4)OCO5)c4[nH]c5ccccc5c4C[C@@H]3C2=O)C1 CHEMBL33381 IC50 31.0 nM
COc1ccc2c(N[C@@H](C)Cc3cc(C)[nH]n3)ncnc2c1OC CHEMBL4128481 IC50 34.7 nM
O=C1[C@H]2Cc3c([nH]c4ccccc34)[C@@H](c3ccc(O)nc3)N2C(=O)CN1[C@@H]1CCN(Cc2ccccc2)C1 CHEMBL34169 IC50 39.0 nM
COCCNc1cc(O)c2c(=O)c3c(-c4nccs4)[nH]c(Cc4ccc5c(c4)OCO5)c3oc2c1 CHEMBL4218772 IC50 39.0 nM
O=C1[C@H]2Cc3c([nH]c4ccccc34)[C@@H](c3ccc4c(c3)OCO4)N2C(=O)CN1[C@@H]1CCN(CCC2CC2)C1 CHEMBL33944 IC50 43.0 nM
CN(C)CC(=O)CN1CC[C@@H](N2CC(=O)N3[C@H](c4ccc5c(c4)OCO5)c4[nH]c5ccccc5c4C[C@@H]3C2=O)C1 CHEMBL284627 IC50 48.0 nM
NC(=O)CCN1CC[C@@H](N2CC(=O)N3[C@H](c4ccc5c(c4)OCO5)c4[nH]c5ccccc5c4C[C@@H]3C2=O)C1 CHEMBL33147 IC50 48.0 nM
CCCSc1nnc2n(-c3ccccc3)c(=O)c3c(C)c(C)sc3n12 CHEMBL3979441 IC50 50.0 nM
CCN(CC)C(=O)c1cc(-c2ccnn2C)nc2c1c(C)nn2-c1ccccc1Cl CHEMBL5415099 IC50 51.0 nM
CN(C)CCN1CC(=O)N2[C@H](c3ccc4c(c3)OCO4)c3[nH]c4ccccc4c3C[C@@H]2C1=O CHEMBL284594 IC50 53.0 nM
CCN(CC)C(=O)c1cc(-c2ccnn2C)nc2c1c(C)nn2-c1ccccc1 CHEMBL5412917 IC50 53.0 nM
CCN(CC)C(=O)c1cc(-c2ccnn2CC)nc2c1c(C)nn2-c1ccccc1 CHEMBL5419115 IC50 61.0 nM
CCN(CC)C(=O)c1cc(-c2ccnn2CC)nc2c1c(C)nn2-c1ccccc1F CHEMBL5396653 IC50 62.0 nM
CCCOCCn1c(=O)c(N[C@H]2CC[C@H](O)CC2)nc2cnc(-c3ccc(OC)nc3)cc21 CHEMBL567470 IC50 64.1 nM
CCCc1nc(C)c2c(NS(C)(=O)=O)nc3ccc(OC)nc3n12 CHEMBL1085374 IC50 68.6 nM
COc1ccc([C@@H]2c3[nH]c4ccccc4c3C[C@@H]3C(=O)N([C@@H]4CCN(Cc5ccccc5)C4)CC(=O)N23)cc1C CHEMBL284535 IC50 71.0 nM
CN1CC(=O)N2[C@H](c3ccc4c(c3)OCO4)c3[nH]c4ccccc4c3C[C@]2(C)C1=O CHEMBL4244897 IC50 73.0 nM
CCN(CC)C(=O)c1cc(-c2ccnn2C)nc2c1c(C(F)(F)F)nn2-c1ccccc1 CHEMBL5430140 IC50 81.0 nM
O=C1[C@H]2Cc3c([nH]c4ccccc34)[C@@H](c3ccc4c(c3)OCO4)N2C(=O)CN1[C@H]1CCN(Cc2ccccc2)C1 CHEMBL284059 IC50 85.0 nM
CCN(CC)C(=O)c1cc(-c2ccnn2C)nc2c1c(C)nn2-c1ccc(F)cc1 CHEMBL5420332 IC50 91.0 nM
CCc1ccc([C@@H]2c3[nH]c4ccccc4c3C[C@@H]3C(=O)N(CC)C(=O)N23)o1 CHEMBL4289291 IC50 99.0 nM
Cc1ccccc1Nc1ncnc2c1c(-c1ccccc1)cn2-c1ccc(F)cc1 CHEMBL2132713 IC50 110.0 nM
C=CCCN1CC[C@@H](N2CC(=O)N3[C@H](c4ccc5c(c4)OCO5)c4[nH]c5ccccc5c4C[C@@H]3C2=O)C1 CHEMBL34628 IC50 118.0 nM
CCc1ccc([C@@H]2c3[nH]c4ccccc4c3C[C@@H]3C(=O)N(C)CC(=O)N23)o1 CHEMBL4281590 IC50 119.0 nM
CCCc1nc(C)c2c(=O)nc(-c3cc(S(=O)(=O)N4CCN(CC)CC4)ccc3OCC)[nH]n12 CHEMBL1520 IC50 130.0 nM
COc1ccc(-c2nc(C(=O)N3CCC4(CC3)C(=O)NCN4c3ccccc3)c(CN)o2)c2ccc(C(F)(F)F)nc12 CHEMBL251107 IC50 130.0 nM
CCN1C(=O)c2nc(Cc3ccccc3)n(Cc3ccccc3)c2N2CC3(CCc4ccccc43)N=C12 CHEMBL1778033 IC50 140.0 nM
Cn1c(NC(=O)c2ccccc2NC(=O)c2ccccc2)nc2ccccc21 CHEMBL2094921 IC50 150.0 nM
CCc1ccc(C2c3[nH]c4ccccc4c3C(=O)CN2c2ncc(-c3ccc(OC)c(OC)c3)cn2)s1 CHEMBL4287438 IC50 153.0 nM
CCN1C(=O)[C@@H]2Cc3c([nH]c4ccccc34)[C@@H](c3sccc3C)N2C1=O CHEMBL4285199 IC50 155.0 nM
CCc1ccc([C@@H]2c3[nH]c4ccccc4c3C[C@@H]3C(=O)N(CC)C(=O)N23)s1 CHEMBL4281081 IC50 169.0 nM
Cc1ccc([C@@H]2c3[nH]c4ccccc4c3C[C@@H]3C(=O)N(C)CC(=O)N23)s1 CHEMBL4278136 IC50 173.0 nM
CCN(CC)C(=O)c1cc(-c2cccs2)nc2c1c(C)nn2-c1ccccc1C CHEMBL3972355 IC50 180.0 nM
CN1CC(=O)N2[C@H](c3ccc(Br)s3)c3[nH]c4ccccc4c3C[C@@H]2C1=O CHEMBL4289471 IC50 219.0 nM
COc1ccc(-c2nc(C(F)(F)F)ncc2C(=O)Nc2c(Cl)cncc2Cl)cc1OC CHEMBL4278921 IC50 245.0 nM
COc1ccc(-c2nc(C(F)(F)F)ncc2C(=O)Nc2ccncc2)cc1OC CHEMBL4282274 IC50 250.0 nM
CCN(CC)C(=O)c1cc(-c2ccnn2CC)nc2c1cnn2-c1ccccc1 CHEMBL5427366 IC50 270.0 nM
CCc1ccc([C@@H]2c3[nH]c4ccccc4c3C[C@@H]3C(=O)N(C)CC(=O)N23)s1 CHEMBL4286052 IC50 272.0 nM
CCCSc1nc2c(c(=O)n1-c1ccccc1)SCC2 CHEMBL3928332 IC50 280.0 nM
COc1ccc(Cn2c(=O)n3ncnc3c3c4c(sc32)CN(CC2CCOCC2)CC4)c(F)c1 CHEMBL4067682 IC50 280.0 nM
COc1cc(-c2cccnc2)cc2c1nc(C)c1c(C)nc(-c3cccnc3)n12 CHEMBL3742354 IC50 286.0 nM
COc1cc(-c2ccc(F)nc2)cc2c1nc(C)c1c(C)nc(-c3cccnc3)n12 CHEMBL3739783 IC50 286.0 nM
COCCOc1nc(-c2ccc(Cl)nc2)nc2c1CN(C(=O)c1ncn3ccccc13)CC2 CHEMBL2204538 Ki 298.0 nM
CCN1C(=O)[C@H]2Cc3c([nH]c4ccccc34)[C@@H](c3ccc(Cl)cc3Cl)N2C1=O CHEMBL1650673 IC50 310.0 nM
O=c1nc2sc3ccccc3n2c(=O)n1-c1ccccc1 CHEMBL3974407 IC50 330.0 nM
CCCOCCn1c(=O)c(NCCN2CCOCC2)nc2cnc(-c3ccc(OC)nc3)cc21 CHEMBL551052 IC50 346.0 nM
CCCCN1C(=O)[C@H]2Cc3c([nH]c4ccccc34)[C@@H](c3ccc(CC)s3)N2C1=O CHEMBL4291228 IC50 386.0 nM
COc1cc(-c2cccnc2)cc2c1nc(C)c1c(C)nc(-c3ccc(F)nc3)n12 CHEMBL3741492 IC50 395.0 nM
OCCN(CCO)c1nc(N2CCCCC2)c2nc(N(CCO)CCO)nc(N3CCCCC3)c2n1 CHEMBL932 Ki 400.0 nM
CCCCSc1nc2c(c(=O)n1-c1ccccc1)SCC2 CHEMBL3955950 IC50 400.0 nM
COc1cc(-c2ccncc2)cc2c1nc(C)c1c(C)nc(-c3ccc(F)nc3)n12 CHEMBL3741207 IC50 413.0 nM
COc1cc(-c2cccnc2)cc2c1nc(C)c1c(C)nc(-c3cccnc3F)n12 CHEMBL3741573 IC50 457.0 nM
COc1ccc(NC(=O)c2cnc(SC)nc2N2CCOCC2)cc1OC CHEMBL4284354 IC50 480.0 nM
COc1cc(Br)cc2c1nc(C)c1c(C)nc(-c3cccnc3F)n12 CHEMBL3741950 IC50 494.0 nM
COc1ccc(-c2nc(C(=O)N3CCC(O)(c4ccccc4)CC3)c(CN)o2)c2ccc(C(F)(F)F)nc12 CHEMBL437020 IC50 500.0 nM
Cc1ccc(-n2cc(-c3ccccc3)c3c(Nc4ccccc4C)ncnc32)cc1 CHEMBL3897311 IC50 500.0 nM
CCN(C)C(=O)c1cc(-c2ccnn2C)nc2c1c(C)nn2-c1ccccc1 CHEMBL5427158 IC50 500.0 nM
CCN1C(=O)c2c(nc(Br)n2Cc2ccc(O)cc2)N2C[C@@H](Cc3ccccc3)N=C12 CHEMBL373102 IC50 540.0 nM
CCN(CC)C(=O)c1cc(-c2cccs2)nc2c1c(C)nn2-c1ccccc1 CHEMBL5437732 IC50 580.0 nM
COc1ccc(-c2nc(C(=O)N3CCN(C(=O)OC(C)(C)C)CC3)c(CN)o2)c2ccc(C(F)(F)F)nc12 CHEMBL249691 IC50 600.0 nM
Cc1nc2c([C@H](C)c3ccc(C(C)(C)C)cc3)nn(CCF)c2c(=O)[nH]1 CHEMBL4871796 IC50 600.0 nM
CCCN(C)C(=O)c1cc(-c2ccnn2C)nc2c1c(C)nn2-c1ccccc1 CHEMBL5420843 IC50 630.0 nM
CCc1ccc(C2c3[nH]c4ccccc4c3C(=O)CN2c2ncc(-c3ccc(OC)c(OC)c3)cn2)o1 CHEMBL4292970 IC50 634.0 nM
COc1ccc(CCNC(=O)c2cnc(SC)nc2N2CCOCC2)cc1OC CHEMBL4283606 IC50 659.0 nM
CCCc1nc(C)c2c(C)nc3ccc(OC)nc3n12 CHEMBL1086110 IC50 690.0 nM
CCc1ccc([C@H]2c3[nH]c4ccccc4c3C[C@@H]3C(=O)N(CC)C(=O)N23)o1 CHEMBL4284224 IC50 802.0 nM
COc1ccc(-c2nc(C(=O)N3CC[C@@H](NC(=O)OC(C)(C)C)C3)c(CN)o2)c2ccc(C(F)(F)F)nc12 CHEMBL399298 IC50 820.0 nM
COc1ccccc1CNC(=O)c1nc(-c2ccc(OC)c3nc(C(F)(F)F)ccc23)oc1CN CHEMBL2012216 IC50 870.0 nM
CCN(CC)C(=O)c1cc(-c2nccs2)nc2c1c(C)nn2-c1ccccc1 CHEMBL5413885 IC50 890.0 nM
O=C1[C@H]2Cc3c([nH]c4ccccc34)[C@@H](c3ccc4c(c3)OCO4)N2C(=O)CN1C1CN(Cc2ccccc2)C1 CHEMBL284719 IC50 950.0 nM
C[C@@H](c1ccc2ncccc2c1)c1nnc2ccc(-c3cccc(C#N)c3)nn12 CHEMBL2431826 IC50 963.0 nM
COc1cc(OC)nc(N2CCN(C(=O)c3nc(-c4ccc(OC)c5nc(C(F)(F)F)ccc45)oc3CN)CC2)n1 CHEMBL401345 IC50 970.0 nM
CCCOc1ccc(NC(=O)CN2CCN(C)CC2)cc1-c1nc(CC)c(CC)c(=O)[nH]1 CHEMBL4462192 IC50 998.0 nM
COc1ccc([C@@H]2c3[nH]c4ccccc4c3C[C@@H]3C(=O)N([C@@H]4CCN(Cc5ccccc5)C4)CC(=O)N23)cc1OC CHEMBL284745 IC50 1000.0 nM
COc1ccc(-c2nc(C(=O)N3CCN(C(=O)c4cc(C)[nH]n4)CC3)c(CN)o2)c2ccc(C(F)(F)F)nc12 CHEMBL250137 IC50 1000.0 nM
COc1ccc(-n2cc(-c3ccccc3)c3c(Nc4ccccc4C)ncnc32)cc1 CHEMBL3890474 IC50 1000.0 nM