CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2Nc2ccccc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3770459 IC50 0.058 nM
COc1ccc2c([C@H]3CCc4ccc(Cl)cc43)nccc2c1OC CHEMBL3601563 IC50 2.4 nM
C[C@@H](Nc1nc2c(cnn2C(C)(C)C)c(=O)n1Cc1ccc(F)cc1)c1ccc(Cl)cc1 CHEMBL4644729 IC50 2.9 nM
COc1ccc(Cn2c(=O)n3ncnc3c3c4c(sc32)CN(CC2CCOCC2)CC4(F)F)cc1 CHEMBL4095097 IC50 3.0 nM
COc1ccc2c(C3CCc4ccc(Cl)cc43)ncnc2c1OC CHEMBL3601549 IC50 4.0 nM
COc1ccc2c([C@H]3CCc4ccc(Cl)cc43)ncnc2c1OC CHEMBL4126270 IC50 4.5 nM
COc1ccc2c(C3CCc4ccc(Br)cc43)ncnc2c1OC CHEMBL3601550 IC50 8.0 nM
COc1ccc2c(N[C@@H](C)Cc3cc(C)[nH]n3)ncnc2c1OC CHEMBL4128481 IC50 9.0 nM
COc1ccc(Cn2c(=O)n3ncnc3c3c4c(sc32)CN(C(=O)C2CC2(F)F)CC4)cc1 CHEMBL4094575 IC50 11.0 nM
COc1ccc2c(NC(C)Cc3cc(C)[nH]n3)ncnc2c1OC CHEMBL4127641 IC50 21.0 nM
COc1ccc2c(C(C)c3cccc(Cl)c3)ncnc2c1OC CHEMBL3601548 IC50 22.0 nM
C[C@@H](Nc1nc2c(cnn2C2CCCC2)c(=O)n1Cc1ccccc1)c1ccc(Cl)cc1 CHEMBL4649493 IC50 23.0 nM
COc1ccc(Cn2c(=O)n3ncnc3c3c4c(sc32)CN(CC2CCOCC2)CC4)c(F)c1 CHEMBL4067682 IC50 26.0 nM
COc1ccc(Cn2c(=O)n3ncnc3c3c4c(sc32)CN(CC2CCOCC2)CC4)cc1 CHEMBL4102858 IC50 27.0 nM
COc1cc2c(NC(C)Cc3cc(C)n[nH]3)ncnc2c(OC)c1OC CHEMBL4128897 IC50 27.0 nM
O=c1n(Cc2ccc(Cl)cc2F)c2sc3c(c2c2ncnn12)CCN(CC1CCOCC1)C3 CHEMBL4078578 IC50 31.0 nM
CCC(CC)Nc1ncnc2c(OC)c(OC)c(OC)cc12 CHEMBL3601554 IC50 35.0 nM
CC(C)c1n[nH]c2c(=O)[nH]c(Cc3cccc(Cl)c3)nc12 CHEMBL512790 IC50 38.0 nM
COc1ccc2c(C3CCc4ccc(F)cc43)ncnc2c1OC CHEMBL3601551 IC50 38.0 nM
O=c1n(Cc2ccc(Cl)cc2)c2sc3c(c2c2ncnn12)CCN(CC1CCOCC1)C3 CHEMBL4090245 IC50 41.0 nM
CN1C(=O)c2c(nc(Cc3ccc(-c4ccccc4)cc3)n2Cc2ccccc2)N2CC3(CCCC3)N=C12 CHEMBL431377 IC50 48.0 nM
C[C@H](Cc1nc2c(cnn2-c2ccccc2Cl)c(=O)[nH]1)C(F)(F)F CHEMBL1513993 IC50 50.0 nM
COc1cc2ncnc(NC(C)Cc3cc(C)n[nH]3)c2cc1OC CHEMBL4127499 IC50 52.0 nM
O=C(C1CC1)N1CCc2c(sc3c2c2ncnn2c(=O)n3Cc2ccc(Cl)cc2)C1 CHEMBL4074038 IC50 53.0 nM
COc1ccc2c(N3C[C@H](C)C[C@H](C)C3)ncnc2c1OC CHEMBL3601558 IC50 70.0 nM
C[C@@H](Nc1nc2c(cnn2C2CCCC2)c(=O)[nH]1)c1ccc(Cl)cc1 CHEMBL4644938 IC50 80.0 nM
COc1cc2ncnc(C3CCc4ccc(Cl)cc43)c2cc1OC CHEMBL3601547 IC50 83.0 nM
COc1cc2ncnc(C(C)c3cccc(Cl)c3)c2cc1OC CHEMBL3601546 IC50 130.0 nM
O=c1n(Cc2ccc(Cl)cc2)c2sc3c(c2c2ncnn12)CCN(C1COC1)C3 CHEMBL4084358 IC50 150.0 nM
O=c1n(Cc2ccccc2)c2sc3c(c2c2ncnn12)CCN(CC1CCOCC1)C3 CHEMBL4069196 IC50 150.0 nM
O=c1n(Cc2ccc(Cl)cc2)c2sc3c(c2c2ncnn12)CCN(Cc1ccccc1)C3 CHEMBL4102318 IC50 190.0 nM
O=c1n(Cc2ccc(Cl)cc2)c2sc3c(c2c2ncnn12)CCN(CC1CC1)C3 CHEMBL4086861 IC50 210.0 nM
CCCN(CCC)c1ncnc2c(OC)c(OC)c(OC)cc12 CHEMBL5269084 IC50 219.0 nM
CC(C)=C[C@H]1Oc2cc(O)ccc2-c2oc3c4c(cc(O)c3c(=O)c21)OC(C)(C)C=C4 CHEMBL4168752 IC50 300.0 nM
CC1=C(C(=O)O[C@H](C)c2ccccc2)C(c2ccc3c(cnn3C)c2)C(C(=O)O[C@H](C)c2ccccc2)=C(C)N1 CHEMBL5180169 IC50 354.0 nM
CCCCCn1c(-c2ccco2)nc2c(NCCCOC)ccnc21 CHEMBL4784075 IC50 360.0 nM
COc1ccc2c([C@@H]3CCc4ccc(Cl)cc43)nccc2c1OC CHEMBL3601564 IC50 458.0 nM
O=c1n(Cc2ccc(Cl)cc2)c2sc3c(c2c2ncnn12)CCCC3 CHEMBL1463540 IC50 460.0 nM
COc1ccc(NC(=O)[C@@H](C)Nc2nc3c(cnn3C3CCCC3)c(=O)[nH]2)cc1 CHEMBL3360415 IC50 473.0 nM
Nc1ncc2cc(-c3nccnc3OC3CN(c4ccc5ccccc5n4)C3)ccc2n1 CHEMBL3356680 IC50 503.0 nM
COc1ccc2c(N[C@H](C)Cc3cc(C)[nH]n3)ncnc2c1OC CHEMBL4129844 IC50 596.0 nM
CC1CCCN1C(=O)[C@@H](C)Nc1nc2c(cnn2C2CCCC2)c(=O)[nH]1 CHEMBL4457086 IC50 700.0 nM
CN1CCc2c(sc3c2c2ncnn2c(=O)n3Cc2ccc(Cl)cc2)C1 CHEMBL4068450 IC50 1000.0 nM