C[C@@H]1CC(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3-c3cccc([N+](=O)[O-])c3)C(=O)CCC2)cc1 CHEMBL338860 IC50 0.11 nM
C[C@@H]1CC(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3-c3ccsc3)C(=O)CCC2)cc1 CHEMBL339210 IC50 0.11 nM
CCc1cc2c(C3=NN(CCCCOc4ccc(C5=NNC(=O)CC5C)cc4)C(=O)CC3)ccc(OC)n2n1 CHEMBL2337969 IC50 0.27 nM
CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3cccc(I)c3)C(=O)CCC2)cc1 CHEMBL131355 IC50 0.33 nM
COc1ccccc1CC1=C(Nc2ccc(C3=NNC(=O)CC3C)cc2)CCCC1=O CHEMBL131111 IC50 0.39 nM
CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3C(F)(F)F)C(=O)CCC2)cc1 CHEMBL338381 IC50 0.83 nM
CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3cccc(Br)c3)C(=O)CCC2)cc1 CHEMBL128621 IC50 0.94 nM
CC1CC(=O)NN=C1c1ccc(/N=C2\CCCC(O)=C2Cc2ccccc2)c(F)c1 CHEMBL128391 IC50 1.2 nM
CCc1cc2c(C3=NN(CCCCOc4ccc(C5=NNC(=O)CC5C)cc4)C(=O)CC3C)ccc(OC)n2n1 CHEMBL2337953 IC50 1.2 nM
C[C@@H]1CC(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3)C(=O)CCC2)cc1 CHEMBL128456 IC50 1.3 nM
CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3)C(=O)CCC2)cc1F CHEMBL338179 IC50 1.6 nM
CC1CC(=O)NN=C1c1cc(F)c(NC2=C(Cc3ccccc3)C(=O)CCC2)cc1F CHEMBL130026 IC50 1.6 nM
CCc1cc2c(C3=NN(CCCCOc4ccc(C5=NNC(=O)CC5C)cc4)C(=O)C3(C)C)ccc(OC)n2n1 CHEMBL2337971 IC50 1.7 nM
Nc1nc2c(ncn2CCCOc2ccc(-c3nnn[nH]3)cc2)c(=O)[nH]1 CHEMBL4741180 IC50 1.89 nM
Nc1ncnc2c1ncn2CCCOc1ccc(-c2nnn[nH]2)cc1 CHEMBL4758355 IC50 2.17 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3c(Cl)cccc3Cl)C(=O)CCC2)cc1F CHEMBL129668 IC50 2.2 nM
COc1ccc(CC2=C(Nc3ccc(C4=NNC(=O)CC4C)cc3)CCCC2=O)cc1 CHEMBL129255 IC50 2.3 nM
O=c1ccn(CCCCOc2ccc(-c3nnn[nH]3)cc2)c(=O)[nH]1 CHEMBL4783647 IC50 2.41 nM
CCc1cc2c(-c3ccc(=O)n(CCCCOc4ccc(C5=NNC(=O)CC5C)cc4)n3)ccc(OC)n2n1 CHEMBL2337970 IC50 2.7 nM
CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3cccc(F)c3)C(=O)CCC2)cc1 CHEMBL341231 IC50 2.8 nM
CC1CC(=O)NN=C1c1ccc(NC(=O)OCc2ccccc2)cc1 CHEMBL129692 IC50 2.9 nM
CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3cccc([N+](=O)[O-])c3)C(=O)CCC2)cc1 CHEMBL341354 IC50 3.1 nM
Cc1cc(C2=NNC(=O)CC2C)ccc1/N=C1\CCCC(O)=C1Cc1ccccc1 CHEMBL131939 IC50 3.7 nM
CCSc1ncc(-c2cc(-c3ccc(Br)cc3)[nH]c(=N)c2C#N)n1Cc1ccccc1 CHEMBL3946861 IC50 3.76 nM
O=C1CCc2cc(OCCCCc3nnnn3C3CCCCC3)ccc2N1 CHEMBL799 IC50 3.89 nM
Nc1ncnc2c1ncn2CCCCOc1ccc(-c2nnn[nH]2)cc1 CHEMBL4792000 IC50 3.91 nM
O=c1ccn(CCCOc2ccc(-c3nnn[nH]3)cc2)c(=O)[nH]1 CHEMBL4777633 IC50 4.0 nM
Cn1c(=O)c2c(ncn2CCCCOc2ccc(-c3nnn[nH]3)cc2)n(C)c1=O CHEMBL4783087 IC50 4.74 nM
COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)CC4)c(F)c3F)C(=O)C2(C)C)n2cc(C(F)(F)F)nc12 CHEMBL2337972 IC50 5.0 nM
O=c1cnn(CCCOc2ccc(-c3nnn[nH]3)cc2)c(=O)[nH]1 CHEMBL4796669 IC50 5.08 nM
COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)CC4)c(F)c3F)C(=O)CC2C)c2cc(C(F)(F)F)nn12 CHEMBL2337968 IC50 5.1 nM
O=c1ccnc(SCCCCOc2ccc(-c3nnn[nH]3)cc2)[nH]1 CHEMBL4754536 IC50 5.13 nM
Cn1c(=O)c2c(ncn2CCCOc2ccc(-c3nnn[nH]3)cc2)n(C)c1=O CHEMBL4757288 IC50 5.83 nM
CCOc1ccc(C2=NNC(=O)O[C@H]2C)cc1C(F)(F)F CHEMBL4862024 IC50 6.0 nM
O=c1ccnc(SCCCOc2ccc(-c3nnn[nH]3)cc2)[nH]1 CHEMBL4748046 IC50 6.22 nM
Cn1cnc2c1c(=O)n(CCCOc1ccc(-c3nnn[nH]3)cc1)c(=O)n2C CHEMBL4752339 IC50 6.29 nM
Cn1cnc2c1c(=O)n(CCCCOc1ccc(-c3nnn[nH]3)cc1)c(=O)n2C CHEMBL4761400 IC50 6.5 nM
O=c1cnn(CCCCOc2ccc(-c3nnn[nH]3)cc2)c(=O)[nH]1 CHEMBL4760080 IC50 6.78 nM
COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)CC4)c(F)c3F)C(=O)C2(C)C)c2sc(C(F)(F)F)nc12 CHEMBL2337973 IC50 6.9 nM
C[C@@H]1OC(=O)NN=C1c1ccc(OCCC(F)(F)F)c(C(F)(F)F)c1 CHEMBL4876937 IC50 7.0 nM
Nc1nc2c(ncn2CCCCOc2ccc(-c3nnn[nH]3)cc2)c(=O)[nH]1 CHEMBL4747854 IC50 7.15 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3Cl)C(=O)CCC2)cc1F CHEMBL130081 IC50 7.2 nM
CC1(C)C(=O)NN=C1c1ccc(/N=C2\CCCC(O)=C2Cc2cccc(C#N)c2)c(F)c1F CHEMBL129283 IC50 7.6 nM
CCCOc1ccc(C2=NNC(=O)O[C@H]2C)cc1C(F)(F)F CHEMBL4877229 IC50 8.0 nM
C[C@@H]1CC(=O)NN=C1c1ccc(Cl)c(Cl)c1 CHEMBL5283715 IC50 8.0 nM
CC(=O)Nc1ccc(C2=NNC(=O)C[C@H]2C)cc1Cl CHEMBL5286823 IC50 8.0 nM
COc1cc2ncnc(N3CCCC(c4ccccc4)C3)c2cc1OC CHEMBL1819121 IC50 8.5 nM
C[C@@H]1OC(=O)NN=C1c1ccc(OC[C@@H](C)F)c(C(F)(F)F)c1 CHEMBL4853029 IC50 9.0 nM
C[C@@H]1CC(=O)NN=C1c1ccc(N2CCOCC2)c(F)c1 CHEMBL5280568 IC50 10.0 nM
CCc1cc2c(C3=NN(CCCOc4ccc(C5=NNC(=O)CC5C)cc4)C(=O)CC3C)ccc(OC)n2n1 CHEMBL2337954 IC50 11.0 nM
C/C(=N\NS(=O)(=O)c1ccc(C)cc1)c1ccc2c(c1)C(C)(C)C(=O)N2 CHEMBL1683806 IC50 14.8 nM
C[C@@H]1CC(=O)NN=C1c1ccc(NC(=O)c2ccccc2C(F)(F)F)cc1 CHEMBL128017 IC50 15.0 nM
COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)C4(C)C)c(F)c3F)C(=O)CC2C)c2cc(C(F)(F)F)nn12 CHEMBL2337967 IC50 15.0 nM
COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)CC4C)cc3)C(=O)CC2C)c2cc(C(F)(F)F)nn12 CHEMBL2337958 IC50 15.0 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3F)C(=O)CCC2)cc1F CHEMBL131672 IC50 16.0 nM
CN(C(=O)CCCOc1ccc2[nH]c(=O)ccc2c1)C1CCCCC1 CHEMBL34431 IC50 16.0 nM
CCn1c(Nc2ccncc2F)nc2c(C3CCCN(C(=O)C4(C#N)CC4)C3)csc2c1=O CHEMBL3360172 IC50 17.0 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3)C(=O)CCC2)cc1F CHEMBL128485 IC50 20.0 nM
Cc1cc(NC2=C(Cc3ccccc3)C(=O)CCC2)ccc1C1=NNC(=O)CC1C CHEMBL421249 IC50 22.0 nM
CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3ccc([N+](=O)[O-])cc3)C(=O)CCC2)cc1 CHEMBL128338 IC50 24.0 nM
CCOC(=O)Nc1ccc(C2=NNC(=O)C[C@H]2C)cc1 CHEMBL129691 IC50 24.0 nM
COc1cc2c(cc1OC)-c1c(-c3cnc(C(=O)N4CCCOCC4)s3)ncn1CC2 CHEMBL2017060 Ki 24.0 nM
CC(=O)Nc1ccc(C2=NNC(=O)C[C@H]2C)cc1 CHEMBL340785 IC50 24.0 nM
CCN(CC)c1ccc(C2=NNC(=O)C[C@H]2C)cc1[N+](=O)[O-] CHEMBL4247714 IC50 25.0 nM
CCN(CC)c1ccc(C2=NNC(=O)CC2C)cc1[N+](=O)[O-] CHEMBL1495092 IC50 25.0 nM
CCn1c(Nc2ccncc2F)nc2c(C3CCCN(C(=O)OC)C3)csc2c1=O CHEMBL3360170 IC50 29.0 nM
CCn1c(Nc2ccncc2F)nc2c(C3CCCN(C(=O)C(C)(C)CO)C3)csc2c1=O CHEMBL3360171 IC50 37.0 nM
Cc1cc(NC2=C(Cc3ccccc3)C(=O)CCC2)ccc1C1=NNC(=O)C1(C)C CHEMBL129689 IC50 38.0 nM
O=C(c1cc2c(s1)CCCC2)N1CCCC(c2ccnc3[nH]ccc23)C1 CHEMBL4745282 IC50 38.0 nM
COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)C4(C)C)c(F)c3F)C(=O)C2(C)C)n2cc(C(F)(F)F)nc12 CHEMBL2337974 IC50 40.0 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3cccc(F)c3)C(=O)CCC2)cc1F CHEMBL129407 IC50 43.0 nM
CC1=C(Nc2ccc(C3=NNC(=O)C[C@H]3C)cc2)CCCC1=O CHEMBL341327 IC50 44.0 nM
CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3)C(=O)CCC2)cc1Cl CHEMBL128783 IC50 46.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4cccc5ccccc45)C3)c2cc1OC CHEMBL263642 Ki 48.0 nM
O=C1CN2Cc3c(ccc(Cl)c3Cl)N=C2N1 CHEMBL760 AC50 48.9 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3)C(=O)CCC2)cc1 CHEMBL128619 IC50 53.0 nM
O=C(c1cc2c(s1)CCCC2)N1CCCC(c2cc(C(F)F)nc3ncnn23)C1 CHEMBL4755779 IC50 56.0 nM
COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)C4(C)C)c(F)c3)C(=O)CC2C)c2cc(C(F)(F)F)nn12 CHEMBL2337966 IC50 58.0 nM
CCOc1cccc(O[C@@H]2CCN(c3ncnc4cc(OC)c(OC)cc34)C2)c1 CHEMBL219451 Ki 61.0 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3ccc(F)cc3)C(=O)CCC2)cc1F CHEMBL128263 IC50 63.0 nM
COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)C4(C)C)c(F)c3F)C(=O)C2(C)C)c2sc(C(F)(F)F)nc12 CHEMBL2337975 IC50 63.0 nM
CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CCC1)[C@@H]2c1ccc(Sc2nc3ccccc3[nH]2)o1 CHEMBL3663741 IC50 68.0 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3cccc(C#N)c3)C(=O)CCC2)cc1F CHEMBL128877 IC50 69.0 nM
COc1ccc(C2=NN(CCCCCOc3ccc(C4=NNC(=O)CC4C)cc3)C(=O)CC2C)c2cc(C(F)(F)F)nn12 CHEMBL2337976 IC50 72.0 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3Cl)C(=O)CCC2)cc1Cl CHEMBL340118 IC50 77.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccccn4)C3)c2cc1OC CHEMBL260006 Ki 77.0 nM
O=C(c1cc2c(s1)CCCC2)N1CCC[C@H](c2ccnc3ncnn23)C1 CHEMBL4761967 IC50 89.0 nM
CC(C)c1cc(C2CCCN(C(=O)c3cc4c(s3)CCCC4)C2)n2ncnc2n1 CHEMBL4764406 IC50 89.0 nM
CCCOc1cc2c(N3CCCC(c4ccccc4)C3)ncnc2cc1OC CHEMBL1819122 IC50 98.0 nM
COc1cc2c(cc1OC)-c1c(-c3cnc(C(=O)N4CCOCC4)s3)ncn1CC2 CHEMBL2017059 Ki 99.0 nM
Cc1nn(C)cc1-c1nn2c([C@@H](C)c3ccc4ncccc4c3)nnc2s1 CHEMBL4783289 IC50 100.0 nM
CCc1cc(NC2=C(Cc3ccccc3)C(=O)CCC2)ccc1C1=NNC(=O)CC1C CHEMBL131118 IC50 101.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccc5ncccc5c4)C3)c2cc1OC CHEMBL263641 Ki 104.0 nM
Cc1cc(C2CCCN(C(=O)c3cc4c(s3)CCCC4)C2)n2ncnc2n1 CHEMBL4742646 IC50 112.0 nM
CC1CC(=O)NN=C1c1ccc(N2CCOCC2)cc1 CHEMBL5267447 IC50 120.0 nM
COc1ccc(O[C@@H]2CCN(c3ncnc4cc(OC)c(OC)cc34)C2)cc1OC CHEMBL409862 Ki 121.0 nM
Cc1cc(NC2=C(Cc3cccc(C#N)c3)C(=O)CCC2)ccc1C1=NNC(=O)C1(C)C CHEMBL341160 IC50 130.0 nM
COc1ccc(C2=NN(CCOc3ccc(C4=NNC(=O)CC4C)cc3)C(=O)CC2C)c2cc(C(F)(F)F)nn12 CHEMBL2337956 IC50 130.0 nM
COc1cccc(-c2ncn3c2-c2cc(OC)c(OC)cc2CC3)c1 CHEMBL2017078 Ki 136.0 nM
COc1ccc(C2=NNC(=O)C2(C)C)n2cc(C(F)(F)F)nc12 CHEMBL2069609 IC50 140.0 nM
COc1ccc(C2=NN(CCCOc3ccc(C4=NNC(=O)CC4C)cc3)C(=O)CC2C)c2cc(C(F)(F)F)nn12 CHEMBL2337957 IC50 140.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccc5c(c4)CCC5)C3)c2cc1OC CHEMBL408977 Ki 141.0 nM
COc1cc2c(cc1OC)-c1c(-c3cnc(CN4CCOCC4)s3)ncn1CC2 CHEMBL2017066 Ki 148.0 nM
COc1cc2c(cc1OC)-c1c(-c3cnc(C(=O)N(C)C(C)(C)C)s3)ncn1CC2 CHEMBL2017057 Ki 149.0 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3cccc([N+](=O)[O-])c3)C(=O)CCC2)cc1F CHEMBL129600 IC50 150.0 nM
COc1ccc(C2=NNC(=O)CC2C)c2sc(C(F)(F)F)nc12 CHEMBL1946933 IC50 150.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4cc5ccccc5cn4)C3)c2cc1OC CHEMBL220185 Ki 151.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccc5nc(C)ccc5c4)C3)c2cc1OC CHEMBL409651 Ki 152.0 nM
CCOc1ccc(O[C@@H]2CCN(c3ncnc4cc(OC)c(OC)cc34)C2)cc1 CHEMBL375200 Ki 161.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ncc(Cl)cn4)C3)c2cc1OC CHEMBL385754 Ki 162.0 nM
COc1cc2c(cc1OC)-c1c(-c3cnc(N4CCOCC4)s3)ncn1CC2 CHEMBL2017065 Ki 177.0 nM
O=C(c1cc2c(s1)CCCC2)N1CCO[C@H](c2ccnc3ncnn23)C1 CHEMBL4796896 IC50 178.0 nM
COc1ccc2cc(O[C@@H]3CCN(c4ncnc5cc(OC)c(OC)cc45)C3)ccc2c1 CHEMBL261711 Ki 199.0 nM
Cc1nn(C)cc1-c1nn2c([C@H](C)c3ccc4ncccc4c3)nnc2s1 CHEMBL4750387 IC50 200.0 nM
Nc1ncc2cc(-c3nccnc3OC3CN(c4ccc5ccccc5n4)C3)ccc2n1 CHEMBL3356680 IC50 208.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccc5cccnc5c4)C3)c2cc1OC CHEMBL409613 Ki 209.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4cnc5ccccc5n4)C3)c2cc1OC CHEMBL219445 Ki 211.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccc(C#N)cc4)C3)c2cc1OC CHEMBL441704 Ki 214.0 nM
COc1cc2c(cc1OC)-c1c(-c3cnc(CN4CCCOCC4)s3)ncn1CC2 CHEMBL2017067 Ki 224.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccncc4)C3)c2cc1OC CHEMBL259295 Ki 226.0 nM
Fc1ccc(-c2csc(-n3cc(-c4nnn[nH]4)cn3)n2)cc1 CHEMBL3614035 IC50 240.0 nM
Cc1[nH]c(=O)c(C#N)cc1-c1ccncc1 CHEMBL189 IC50 250.0 nM
COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)C4(C)C)cc3)C(=O)CC2C)c2cc(C(F)(F)F)nn12 CHEMBL2337962 IC50 270.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4cccc(-c5ccccc5)c4)C3)c2cc1OC CHEMBL218855 Ki 271.0 nM
COc1ccc2ccc(O[C@@H]3CCN(c4ncnc5cc(OC)c(OC)cc45)C3)cc2c1 CHEMBL218955 Ki 273.0 nM
CCOc1cccc(-c2ncn3c2-c2cc(OC)c(OC)cc2CC3)c1 CHEMBL2017080 Ki 277.0 nM
COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC CHEMBL19224 Ki 279.0 nM
NC(=O)c1ccc(-c2cc(Cl)c3c(c2)C2(CCCCC2)NC(=O)N3)cc1 CHEMBL185296 IC50 280.0 nM
CS(=O)(=O)n1ccc2cc(C(=O)N3CCC[C@H](c4ccnc5ncnn45)C3)ccc21 CHEMBL4758144 IC50 282.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccc5ccccc5c4)C3)c2cc1OC CHEMBL410834 Ki 283.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4cccnc4)C3)c2cc1OC CHEMBL374993 Ki 302.0 nM
CC(=O)n1ccc2cc(C(=O)N3CCCC(c4ccnc5ncnn45)C3)ccc21 CHEMBL4783572 IC50 331.0 nM
COc1ccc(C2=NNC(=O)CC2C)c2cc(C(F)(F)F)nn12 CHEMBL2069600 IC50 360.0 nM
COc1ccc(C2=NNC(=O)C[C@@H]2C)c2cc(C(F)(F)F)nn12 CHEMBL2337955 IC50 360.0 nM
COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)CC4)cc3)C(=O)CC2C)c2cc(C(F)(F)F)nn12 CHEMBL2337960 IC50 360.0 nM
COC1=CC=C(C2=NN(CCCCCOc3ccc(C4=NNC(=O)CC4C)cc3)C(=O)CC2C)C2CC(C(F)(F)F)=NN12 CHEMBL4761658 IC50 360.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4cccc(C(C)C)c4)C3)c2cc1OC CHEMBL219123 Ki 370.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccccc4C(C)C)C3)c2cc1OC CHEMBL429686 Ki 370.0 nM
O=C(c1ccc2c(c1)OCCO2)N1CCC[C@H](c2ccnc3ncnn23)C1 CHEMBL4793775 IC50 398.0 nM
Cc1cc(=O)[nH]c2ccc(OCc3cccc(C(=O)N4CCC(C)CC4)c3)cc12 CHEMBL592243 IC50 430.0 nM
O=C(c1ccc(C(F)(F)F)cc1)N1CCC[C@H](c2ccnc3ncnn23)C1 CHEMBL4799257 IC50 436.0 nM
COc1cc2c(cc1OC)-c1c(-c3cccnc3)ncn1CC2 CHEMBL2017083 Ki 449.0 nM
COc1ccc(-c2nc3cc(C4=NNC(=O)CC4C)ccc3[nH]2)cc1 CHEMBL24646 AC50 450.0 nM
O=C(NNC(=S)Nc1ccc(Cl)c(Cl)c1)c1ccccc1O CHEMBL4476621 IC50 490.0 nM
C[C@@H](c1ccc2ncccc2c1)c1nnc2sc(-c3cnn(C)c3)nn12 CHEMBL4791034 IC50 500.0 nM
COc1ccc(C(=O)N2CCC[C@H](c3ccnc4ncnn34)C2)cc1 CHEMBL4763230 IC50 537.0 nM
COc1cc2c(cc1OC)-c1c(-c3cnc(CO)s3)ncn1CC2 CHEMBL2017064 Ki 540.0 nM
COc1ccc(C2=NNC(=O)C2(C)C)c2sc(C(F)(F)F)nc12 CHEMBL2069607 IC50 540.0 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3cccc([N+](=O)[O-])c3)C(=O)CCC2)cc1Cl CHEMBL273816 IC50 550.0 nM
COc1cc2c(cc1OC)-c1c(-c3cncs3)ncn1CC2 CHEMBL2017087 Ki 555.0 nM
C[C@@H](c1ccc2ncccc2c1)n1nnc2ncc(-c3cnn(CCO)c3)nc21 CHEMBL2431835 IC50 589.0 nM
COc1ccc(C2=NN(CCCCOc3cccc(C4=NNC(=O)CC4C)c3)C(=O)CC2C)c2cc(C(F)(F)F)nn12 CHEMBL2337963 IC50 590.0 nM
Cc1cc(=O)[nH]c2ccc(OCc3cccc(C(=O)N4CCCC4)c3)cc12 CHEMBL592057 IC50 640.0 nM
Cc1cc(=O)[nH]c2ccc(OCc3cccc(C(=O)N4CCCCC4)c3)cc12 CHEMBL592242 IC50 660.0 nM
Cc1[nH]c(=O)c(C#N)cc1-c1ccc2nccn2c1 CHEMBL1474900 AC50 707.6 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccc(C(C)(C)C)cc4)C3)c2cc1OC CHEMBL387167 Ki 720.0 nM
COc1cc2c(cc1OC)-c1c(-c3cccnc3)nc(C)n1CC2 CHEMBL2017086 Ki 727.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccc(OC(F)(F)F)cc4)C3)c2cc1OC CHEMBL387166 Ki 739.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccccc4OC(F)(F)F)C3)c2cc1OC CHEMBL430071 Ki 739.0 nM
CCOc1ccc(OC2CCN(c3ncc(C(=O)NO)cn3)CC2)cc1-c1nc2c(CC)nn(C)c2c(=O)[nH]1 CHEMBL3936651 IC50 750.0 nM
CS(=O)(=O)n1ccc2cc(C(=O)N3CCCC(c4ccnc5ncnn45)C3)ccc21 CHEMBL4788385 IC50 776.0 nM
Cn1ncc(-c2ccncc2)c1-c1ccc(OCc2cc(-n3cc(CCF)nn3)c3ccccc3n2)cc1 CHEMBL3629000 IC50 810.0 nM
C[C@@H]1CCN(c2cc(-c3ccccc3)ccn2)C[C@H]1c1cc(C(F)F)nc2ncnn12 CHEMBL4741218 IC50 813.0 nM
COc1cc2c(cc1OC)-c1c(-c3cnc(C(=O)NC4CCOCC4)s3)ncn1CC2 CHEMBL2017061 Ki 828.0 nM
Cc1cc(=O)[nH]c2ccc(OCc3cccc(C(=O)N4CCC(C(=O)O)CC4)c3)cc12 CHEMBL591997 IC50 840.0 nM
COc1ccc(C(=O)N2CC[C@@H](C)[C@H](c3cc(C(F)F)nc4ncnn34)C2)cc1OC CHEMBL4754478 IC50 912.0 nM
CC(=O)Oc1c(C)c(C)c2c(c1C)CC[C@@](C)(CCC[C@H](C)CCC[C@H](C)CCCC(C)C)O2 CHEMBL1047 AC50 932.7 nM
COc1cc2c(cc1OC)-c1c(-c3cccc(Cl)c3)ncn1CC2 CHEMBL2017075 Ki 954.0 nM
COc1cc2c(cc1OC)-c1c(-c3cncs3)nc(C)n1CC2 CHEMBL2017058 Ki 968.0 nM
COc1ccc(C2=NNC(=O)CC2C)c2ccc(C(F)(F)F)nc12 CHEMBL1946935 IC50 970.0 nM