C[C@@H]1CC(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3-c3cccc([N+](=O)[O-])c3)C(=O)CCC2)cc1 CHEMBL338860 IC50 0.049 nM
C[C@@H]1CC(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3-c3ccsc3)C(=O)CCC2)cc1 CHEMBL339210 IC50 0.068 nM
CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3cccc(I)c3)C(=O)CCC2)cc1 CHEMBL131355 IC50 0.11 nM
COc1ccccc1CC1=C(Nc2ccc(C3=NNC(=O)CC3C)cc2)CCCC1=O CHEMBL131111 IC50 0.13 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3c(Cl)cccc3Cl)C(=O)CCC2)cc1F CHEMBL129668 IC50 0.13 nM
C[C@@H]1CC(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3)C(=O)CCC2)cc1 CHEMBL128456 IC50 0.19 nM
CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3)C(=O)CCC2)cc1F CHEMBL338179 IC50 0.24 nM
CC1CC(=O)NN=C1c1ccc(/N=C2\CCCC(O)=C2Cc2ccccc2)c(F)c1 CHEMBL128391 IC50 0.26 nM
CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3cccc(Br)c3)C(=O)CCC2)cc1 CHEMBL128621 IC50 0.3 nM
CC1(C)C(=O)NN=C1c1ccc(/N=C2\CCCC(O)=C2Cc2cccc(C#N)c2)c(F)c1F CHEMBL129283 IC50 0.33 nM
CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3C(F)(F)F)C(=O)CCC2)cc1 CHEMBL338381 IC50 0.35 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3Cl)C(=O)CCC2)cc1F CHEMBL130081 IC50 0.53 nM
Cc1cc(C2=NNC(=O)CC2C)ccc1/N=C1\CCCC(O)=C1Cc1ccccc1 CHEMBL131939 IC50 0.61 nM
CC1CC(=O)NN=C1c1cc(F)c(NC2=C(Cc3ccccc3)C(=O)CCC2)cc1F CHEMBL130026 IC50 0.62 nM
CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3cccc(F)c3)C(=O)CCC2)cc1 CHEMBL341231 IC50 0.7 nM
COc1ccc(CC2=C(Nc3ccc(C4=NNC(=O)CC4C)cc3)CCCC2=O)cc1 CHEMBL129255 IC50 0.7 nM
CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3cccc([N+](=O)[O-])c3)C(=O)CCC2)cc1 CHEMBL341354 IC50 0.94 nM
CC1CC(=O)NN=C1c1ccc(NC(=O)OCc2ccccc2)cc1 CHEMBL129692 IC50 1.0 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3F)C(=O)CCC2)cc1F CHEMBL131672 IC50 1.1 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3)C(=O)CCC2)cc1F CHEMBL128485 IC50 2.5 nM
Cc1cc(NC2=C(Cc3ccccc3)C(=O)CCC2)ccc1C1=NNC(=O)CC1C CHEMBL421249 IC50 2.6 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3ccc(F)cc3)C(=O)CCC2)cc1F CHEMBL128263 IC50 3.1 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3cccc(C#N)c3)C(=O)CCC2)cc1F CHEMBL128877 IC50 3.2 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3cccc([N+](=O)[O-])c3)C(=O)CCC2)cc1F CHEMBL129600 IC50 4.5 nM
Cc1cc(NC2=C(Cc3ccccc3)C(=O)CCC2)ccc1C1=NNC(=O)C1(C)C CHEMBL129689 IC50 4.8 nM
CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3)C(=O)CCC2)cc1Cl CHEMBL128783 IC50 4.8 nM
C[C@@H]1CC(=O)NN=C1c1ccc(NC(=O)c2ccccc2C(F)(F)F)cc1 CHEMBL128017 IC50 5.0 nM
C[C@@H]1OC(=O)NN=C1c1ccc(OCCC(F)(F)F)c(C(F)(F)F)c1 CHEMBL4876937 IC50 5.0 nM
CCCOc1ccc(C2=NNC(=O)O[C@H]2C)cc1C(F)(F)F CHEMBL4877229 IC50 5.0 nM
CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3ccc([N+](=O)[O-])cc3)C(=O)CCC2)cc1 CHEMBL128338 IC50 5.5 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3cccc(F)c3)C(=O)CCC2)cc1F CHEMBL129407 IC50 5.6 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3Cl)C(=O)CCC2)cc1Cl CHEMBL340118 IC50 6.3 nM
CCOc1ccc(C2=NNC(=O)O[C@H]2C)cc1C(F)(F)F CHEMBL4862024 IC50 7.0 nM
CCOC(=O)Nc1ccc(C2=NNC(=O)C[C@H]2C)cc1 CHEMBL129691 IC50 8.5 nM
CC1=C(Nc2ccc(C3=NNC(=O)C[C@H]3C)cc2)CCCC1=O CHEMBL341327 IC50 8.8 nM
C[C@@H]1OC(=O)NN=C1c1ccc(OC[C@@H](C)F)c(C(F)(F)F)c1 CHEMBL4853029 IC50 9.0 nM
Cc1cc(NC2=C(Cc3cccc(C#N)c3)C(=O)CCC2)ccc1C1=NNC(=O)C1(C)C CHEMBL341160 IC50 10.0 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3)C(=O)CCC2)cc1 CHEMBL128619 IC50 10.0 nM
CC(=O)Nc1ccc(C2=NNC(=O)C[C@H]2C)cc1Cl CHEMBL5286823 IC50 10.0 nM
C[C@@H]1CC(=O)NN=C1c1ccc(Cl)c(Cl)c1 CHEMBL5283715 IC50 14.0 nM
CC(=O)Nc1ccc(C2=NNC(=O)C[C@H]2C)cc1 CHEMBL340785 IC50 16.0 nM
CN(C(=O)CCCOc1ccc2[nH]c(=O)ccc2c1)C1CCCCC1 CHEMBL34431 IC50 18.0 nM
CCc1cc(NC2=C(Cc3ccccc3)C(=O)CCC2)ccc1C1=NNC(=O)CC1C CHEMBL131118 IC50 21.0 nM
CC1CC(=O)NN=C1c1ccc(N2CCOCC2)c(F)c1 CHEMBL5273714 IC50 27.0 nM
CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3cccc([N+](=O)[O-])c3)C(=O)CCC2)cc1Cl CHEMBL273816 IC50 30.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4cccc5ccccc45)C3)c2cc1OC CHEMBL263642 Ki 56.0 nM
O=C(c1cc2c(s1)CCCC2)N1CCCC(c2cc(C(F)F)nc3ccnn23)C1 CHEMBL4751598 IC50 78.0 nM
CCOc1cccc(O[C@@H]2CCN(c3ncnc4cc(OC)c(OC)cc34)C2)c1 CHEMBL219451 Ki 88.0 nM
C[C@@H](c1ccc2ncccc2c1)c1nnc2ccc(-c3cccc(C#N)c3)nn12 CHEMBL2431826 IC50 88.0 nM
C/C(=N\NS(=O)(=O)c1ccc(C)cc1)c1ccc2c(c1)C(C)(C)C(=O)N2 CHEMBL1683806 IC50 88.4 nM
CCN(CC)c1ccc(C2=NNC(=O)C[C@H]2C)cc1[N+](=O)[O-] CHEMBL4247714 IC50 100.0 nM
CCN(CC)c1ccc(C2=NNC(=O)CC2C)cc1[N+](=O)[O-] CHEMBL1495092 IC50 100.0 nM
C[C@@H](c1ccc2ncccc2c1)c1nnc2ccc(-c3ccc(F)c(F)c3)nn12 CHEMBL2431822 IC50 107.0 nM
COc1cc(C2CCCN(C(=O)c3cc4c(s3)CCCC4)C2)n2ncnc2n1 CHEMBL4746828 IC50 115.0 nM
C[C@@H](c1ccc2ncccc2c1)c1nnc2ccc(-c3cnn(C)c3)nn12 CHEMBL2431819 IC50 150.0 nM
COc1ccc(-c2nc(C(F)(F)F)ncc2C(=O)Nc2ccncc2)cc1OC CHEMBL4282274 IC50 169.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4cc5ccccc5cn4)C3)c2cc1OC CHEMBL220185 Ki 196.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccc5ncccc5c4)C3)c2cc1OC CHEMBL263641 Ki 201.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccccn4)C3)c2cc1OC CHEMBL260006 Ki 207.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccc5nc(C)ccc5c4)C3)c2cc1OC CHEMBL409651 Ki 223.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccc5c(c4)CCC5)C3)c2cc1OC CHEMBL408977 Ki 237.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccc5cccnc5c4)C3)c2cc1OC CHEMBL409613 Ki 240.0 nM
CC(C)Cn1c(=O)n(C)c(=O)c2nc[nH]c21 CHEMBL275084 IC50 242.0 nM
COc1ccc(O[C@@H]2CCN(c3ncnc4cc(OC)c(OC)cc34)C2)cc1OC CHEMBL409862 Ki 260.0 nM
CC1CC(=O)NN=C1c1ccc(N2CCOCC2)cc1 CHEMBL5267447 IC50 260.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4cnc5ccccc5n4)C3)c2cc1OC CHEMBL219445 Ki 273.0 nM
Cc1[nH]c(=O)c(C#N)cc1-c1ccncc1 CHEMBL189 IC50 280.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4cccc(-c5ccccc5)c4)C3)c2cc1OC CHEMBL218855 Ki 280.0 nM
COc1ccc2cc(O[C@@H]3CCN(c4ncnc5cc(OC)c(OC)cc45)C3)ccc2c1 CHEMBL261711 Ki 280.0 nM
COc1ccc2ccc(O[C@@H]3CCN(c4ncnc5cc(OC)c(OC)cc45)C3)cc2c1 CHEMBL218955 Ki 305.0 nM
COc1ccc(-c2nc(C(F)(F)F)ncc2C(=O)Nc2c(Cl)cncc2Cl)cc1OC CHEMBL4278921 IC50 321.0 nM
CCOc1ccc(O[C@@H]2CCN(c3ncnc4cc(OC)c(OC)cc34)C2)cc1 CHEMBL375200 Ki 328.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ncc(Cl)cn4)C3)c2cc1OC CHEMBL385754 Ki 332.0 nM
Cc1cc(C2CCCN(C(=O)c3cc4c(s3)CCCC4)C2)n2ccnc2n1 CHEMBL4764226 IC50 347.0 nM
COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC CHEMBL19224 Ki 417.0 nM
C[C@@H](c1ccc2ncccc2c1)n1nnc2ncc(-c3cnn(CCO)c3)nc21 CHEMBL2431835 IC50 420.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccc5ccccc5c4)C3)c2cc1OC CHEMBL410834 Ki 463.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccc(C#N)cc4)C3)c2cc1OC CHEMBL441704 Ki 471.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4cccc(C(C)C)c4)C3)c2cc1OC CHEMBL219123 Ki 474.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccccc4C(C)C)C3)c2cc1OC CHEMBL429686 Ki 474.0 nM
O=C(C1CCCCC1)N1CCCC(c2ccnc3ncnn23)C1 CHEMBL4791830 IC50 617.0 nM
N#Cc1cc(C2CCCN(C(=O)c3cc4c(s3)CCCC4)C2)n2ncnc2n1 CHEMBL4761452 IC50 676.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4ccncc4)C3)c2cc1OC CHEMBL259295 Ki 685.0 nM
C[C@@H](c1ccc2ncccc2c1)n1nnc2ncc(-c3cnn(C)c3)nc21 CHEMBL2431834 IC50 699.0 nM
COc1ccc(OC)c(-c2nnc3n2N=C(c2ccc(OC)c(OC)c2)CS3)c1 CHEMBL252387 IC50 720.0 nM
COc1cc2ncnc(N3CC[C@@H](Oc4cccnc4)C3)c2cc1OC CHEMBL374993 Ki 748.0 nM
COc1ccc(NC(=O)c2cnc(SC)nc2N2CCOCC2)cc1OC CHEMBL4284354 IC50 800.0 nM
Cc1cc(=O)[nH]c2ccc(OCc3cccc(C(=O)N4CCC(O)CC4)c3)cc12 CHEMBL592241 IC50 910.0 nM
COc1ccc(NC(=O)c2cnc(C(F)(F)F)nc2N2CCOCC2)cc1OC CHEMBL4295242 IC50 950.0 nM