CCOc1cc([C@H](Cc2c(Cl)c[n+]([O-])cc2Cl)OC(=O)c2ccc(CN[C@@](CO)(C(=O)O[C@H]3CN4CCC3CC4)c3ccccc3)s2)ccc1OC CHEMBL5417689 pIC50 0.03162 nM
Cc1noc(/C(=C/c2cccc(-n3cc(C(=O)Nc4c(Cl)cncc4Cl)c(=O)c4cccnc43)c2)c2ccc(S(C)(=O)=O)cc2)n1 CHEMBL499477 IC50 0.06 nM
O=[N+]([O-])c1cccc(-c2cc(Cc3ccncc3)cc3cccnc23)c1 CHEMBL127944 IC50 0.07 nM
CC(C)NC(=O)N(Cc1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 CHEMBL377709 IC50 0.1 nM
CC(C)(C#N)c1cc(-c2cccc(CN(C(=O)Nc3ccccc3)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 CHEMBL380321 IC50 0.1 nM
CC(C)NC(=O)N(Cc1cccc(-c2cc(C(C)(C)C#N)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 CHEMBL382168 IC50 0.1 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(C3(C(=O)NC4CCCC4)CC3)nc12 CHEMBL3676245 IC50 0.1 nM
CNc1nc(NC2(C#N)CCCCC2C)nc(-n2cncn2)n1 CHEMBL2402362 IC50 0.15 nM
Cc1noc(/C(=C/c2cccc(-c3cc(C(C)C)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)n1 CHEMBL381681 IC50 0.16 nM
CC(=O)c1cccc(-c2cccc(-n3cc(C(=O)Nc4nccc(Cl)c4Cl)c(=O)c4cccnc43)c2)c1 CHEMBL514564 IC50 0.17 nM
[N-]=[N+]=Nc1cccc(-c2cc(Cc3ccncc3)cc3cccnc23)c1 CHEMBL339083 IC50 0.2 nM
Cc1ccc(/C(=C/c2cccc(-c3cc(C(C)C)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)nc1 CHEMBL197392 IC50 0.2 nM
CC(C)(C#N)c1cc(-c2cccc(CN(C(=O)c3ccccc3)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 CHEMBL383225 IC50 0.2 nM
CNc1nc(NC2(C#N)CCCC(C)C2)nc(-n2cncn2)n1 CHEMBL2402363 IC50 0.2 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(C3(C(=O)NCC(C)(C)C)CC3)nc12 CHEMBL3676244 IC50 0.2 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(C3(C(=O)NC(C)C)CC3)nc12 CHEMBL3676246 IC50 0.2 nM
O=C(Nc1c(Cl)cncc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1 CHEMBL193240 IC50 0.21 nM
CC(=O)CCCOc1nc(Oc2ccc3c(c2)COB3O)c(C#N)cc1Cl CHEMBL3694420 IC50 0.25 nM
CCNC(=O)Nc1cccc([C@@H](Cc2ccncc2)c2ccc(OC)c(OC3CCCC3)c2)c1 CHEMBL418416 IC50 0.3 nM
C[C@H](c1ccccc1)N(C)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL165889 IC50 0.3 nM
CC(C)NC(=O)/C(=C/c1cccc(-c2cc(C(C)C)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 CHEMBL371089 IC50 0.3 nM
CC(C)c1cc(-c2cccc(/C=C(/C(=O)O)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 CHEMBL197386 IC50 0.3 nM
CC(C)OC(=O)N(Cc1cccc(-c2cc(C(C)(C)C#N)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 CHEMBL209295 IC50 0.3 nM
Cc1cc(C(=O)N(Cc2cccc(-c3cc(C(C)(C)C#N)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)no1 CHEMBL206968 IC50 0.3 nM
CC(C)Nc1nc2oc3c(NCCCN4CCCC4=O)ncnc3c2c2c1CCC(C)(C)C2 CHEMBL1830646 IC50 0.3 nM
CCCNC(=O)C1(c2nc3c(OC)ccc(C(=O)Cc4c(Cl)cncc4Cl)n3n2)CC1 CHEMBL3639751 IC50 0.3 nM
CC(C)(c1cc(-c2cccc(-c3ccc(C4CC4C(=O)O)cc3)c2)c2ncccc2c1)S(C)(=O)=O CHEMBL253083 IC50 0.32 nM
CC(=O)c1ccc(-c2cccc(-n3cc(C(=O)NC(C)C)c(=O)c4cccnc43)c2)cc1 CHEMBL519193 IC50 0.34 nM
O=C(NCC1CC1)c1cn(-c2cccc(-c3ccc(C4CC4C(=O)O)cc3)c2)c2ncccc2c1=O CHEMBL1801156 IC50 0.35 nM
CC(=O)c1cccc(-c2cccc(-n3cc(C(=O)NC(C)C)c(=O)c4cccnc43)c2)c1 CHEMBL464804 IC50 0.37 nM
Cc1ccc(O)c(C(=O)N[C@H]2CC[C@@H](NC(=O)c3cc(F)cnc3Oc3ccc(F)c(F)c3)CC2)c1 CHEMBL3113734 IC50 0.38 nM
[O-][n+]1ccc(CC(c2ccc(OC(F)F)c(OC3CC3)c2)c2cnc(C(O)(C(F)(F)F)C(F)(F)F)s2)cc1 CHEMBL2112296 IC50 0.4 nM
[N-]=[N+]=Nc1cccc(-c2cc(Cn3cnc(I)c3)cc3cccnc23)c1 CHEMBL419236 IC50 0.4 nM
CC(C)c1cc(-c2cccc(/C=C(/c3ccc(C(C)(C)O)cc3)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 CHEMBL198674 IC50 0.4 nM
[O-][n+]1cccc(C[C@@H](c2ccc(OC(F)F)c(OC3CC3)c2)c2cnc(C(O)(C(F)(F)F)C(F)(F)F)s2)c1 CHEMBL199015 IC50 0.4 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(C3(C(=O)NCc4ccncc4)CC3)nc12 CHEMBL3676243 IC50 0.4 nM
CNc1nc(NC2(C#N)CCCCCC2)nc(-n2cncn2)n1 CHEMBL2402361 IC50 0.42 nM
O=C(Nc1c(Cl)cncc1Cl)c1cn(-c2ccc(Cl)cc2)c2ncccc2c1=O CHEMBL456171 IC50 0.45 nM
O=C(NC1CC1)c1cn(-c2cccc(-c3ccc([C@H]4C[C@@H]4C(=O)O)c(F)c3)c2)c2ncccc2c1=O CHEMBL1801161 IC50 0.46 nM
CC(C)c1cc(-c2cccc(/C=C(\c3ccc(S(C)(=O)=O)cc3)c3nccs3)c2)c2ncccc2c1 CHEMBL196969 IC50 0.47 nM
[O-][n+]1ccc(CC(c2ccc(COc3ccc(F)cc3)cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL36348 IC50 0.5 nM
CC(C)(O)c1ncc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC3CCC3)c2)s1 CHEMBL310303 IC50 0.5 nM
Cc1noc(/C(=C/c2cccc(-c3cc(C(C)C)cc4cccnc34)c2)c2ccccn2)n1 CHEMBL197494 IC50 0.5 nM
CC(C)Nc1nc2oc3c(NCCN4CCOCC4)ncnc3c2c2c1CCC(C)(C)C2 CHEMBL1830643 IC50 0.5 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(C3(C(=O)NCc4ccccc4)CC3)nc12 CHEMBL3676240 IC50 0.5 nM
O=C(NCC(F)(F)F)c1cn(-c2cccc(-c3ccc(C4CC4C(=O)O)cc3)c2)c2ncccc2c1=O CHEMBL1801155 IC50 0.51 nM
O=C(NC1CCC1)c1cn(-c2cccc(-c3ccc(C4CC4C(=O)O)cc3)c2)c2ncccc2c1=O CHEMBL1801157 IC50 0.52 nM
O=C(NC1CC1)c1cn(-c2cccc(-c3ccc([C@@H]4C[C@H]4C(=O)O)c(F)c3)c2)c2ncccc2c1=O CHEMBL1801160 IC50 0.53 nM
O=C(NC1CC1)c1cn(-c2cccc(-c3cccc(C4CC4C(=O)O)c3)c2)c2ncccc2c1=O CHEMBL1801068 IC50 0.54 nM
O=C(NC1CC1)c1cn(-c2cccc(-c3ccc(C4CC4c4nnn[nH]4)cc3)c2)c2ncccc2c1=O CHEMBL1801151 IC50 0.55 nM
O=C(NC1CC1)c1cn(-c2cccc(-c3ccc(C4CC4C(=O)O)cc3)c2)c2ncccc2c1=O CHEMBL1801067 IC50 0.57 nM
CC1(NC(=O)c2cn(-c3cccc(-c4ccc(C5CC5C(=O)O)cc4)c3)c3ncccc3c2=O)CC1 CHEMBL1801154 IC50 0.58 nM
CCN(c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1)[C@H](C)c1ccccc1 CHEMBL165687 IC50 0.6 nM
CC(O)(c1ccccc1)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL61191 IC50 0.6 nM
O=c1c2c(ncn2Cc2ccccc2)c2cccnc2n1-c1ccccc1 CHEMBL318502 IC50 0.6 nM
CC(C)NC(=O)N(Cc1cc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)ccc1F)c1ccc(S(C)(=O)=O)cc1 CHEMBL208100 IC50 0.6 nM
CC(C)(c1cc(-c2cccc(C(=O)Nc3c(Cl)cncc3Cl)c2)c2ncccc2c1)S(C)(=O)=O CHEMBL207996 IC50 0.6 nM
CC(C)NC(=O)c1cn(-c2cccc(-c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1=O CHEMBL484753 IC50 0.62 nM
O=C(NC1CC1)c1cn(-c2cccc(-c3ccc([C@H]4C[C@@H]4C(=O)O)cc3)c2)c2ncccc2c1=O CHEMBL1801159 IC50 0.66 nM
CC(C)(O)c1ccc(C(CC2=CCC(=O)N=C2)c2ccc(OC(F)F)c(OC3CC3)c2)cn1 CHEMBL81491 IC50 0.7 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(C3(C(=O)NCc4cccnc4)CC3)nc12 CHEMBL3676242 IC50 0.7 nM
CSc1ccc(-c2cccc(-n3cc(C(=O)NC(C)C)c(=O)c4cccnc43)c2)cc1 CHEMBL485547 IC50 0.75 nM
COc1ccc([C@H](Cc2ccncc2)c2ccc(N3CCCS3(=O)=O)cc2)cc1OC1CCCC1 CHEMBL35562 IC50 0.8 nM
CN(c1ccccc1)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL162485 IC50 0.8 nM
CC(C)(Nc1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1)c1ccccc1 CHEMBL351187 IC50 0.8 nM
[O-][n+]1ccc(CC(c2ccc(OC(F)F)c(OC3CCC3)c2)c2cnc(C(O)(C(F)(F)F)C(F)(F)F)s2)cc1 CHEMBL2112295 IC50 0.8 nM
[O-][n+]1ccc(CC(c2ccc(C(O)(c3ccccc3)c3ccccc3)nc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL299931 IC50 0.8 nM
CC(C)C(O)(c1ccccc1)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL294717 IC50 0.8 nM
CC(C)NC(=O)/C(=C/c1cccc(-c2cc(C(C)(C)C#N)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 CHEMBL371037 IC50 0.8 nM
CC(C)(Nc1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1)c1ccccc1 CHEMBL452578 IC50 0.8 nM
CC(=O)CCCOc1nc(Oc2ccc3c(c2)COB3O)c(Cl)cc1C#N CHEMBL3694410 IC50 0.8 nM
CCC(C#N)(CC)Nc1nc(NC)nc(-n2cncn2)n1 CHEMBL2402509 IC50 0.81 nM
CC(C)(CC(=O)O)c1ccc(-c2cccc(-n3cc(C(=O)NC4CC4)c(=O)c4cccnc43)c2)cc1 CHEMBL1801071 IC50 0.85 nM
CC(C)(Cc1ccc(-c2cccc(-n3cc(C(=O)NC4CC4)c(=O)c4cccnc43)c2)cc1)C(=O)O CHEMBL1801070 IC50 0.88 nM
CNc1nc(NC(C#N)(C2CC2)C2CC2)nc(-n2cncn2)n1 CHEMBL2402511 IC50 0.89 nM
CC(C)NC(=O)/C(=C/c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 CHEMBL198527 IC50 0.9 nM
CC(C)Nc1nc2oc3c(NCc4cccnc4)ncnc3c2c2c1CCC(C)(C)C2 CHEMBL1828652 IC50 0.9 nM
CC(C)(O)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC3CCC3)c2)cn1 CHEMBL78806 IC50 1.0 nM
CCC(O)(c1ccccc1)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL57524 IC50 1.0 nM
CC(C)NC(=O)/C(=C\c1cccc(-c2cc(C(C)(C)C#N)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 CHEMBL198853 IC50 1.0 nM
CC(C)(C#N)c1cc(-c2cccc(CN(Cc3ccc(F)cc3)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 CHEMBL378681 IC50 1.0 nM
Cc1noc(/C(=C/c2cccc(-c3cc(C(C)(C)S(C)(=O)=O)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)n1 CHEMBL372575 IC50 1.0 nM
O=C(NC1CC1)c1cn(-c2cccc(-c3ccc([C@@H]4C[C@H]4C(=O)O)cc3)c2)c2ncccc2c1=O CHEMBL1801158 IC50 1.0 nM
CNc1nc(NC2(C#N)CCCCC2)nc(-n2cnc(C)n2)n1 CHEMBL2402358 IC50 1.0 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(C3(C(=O)NCc4ccccn4)CC3)nc12 CHEMBL3676241 IC50 1.0 nM
CCCC(C#N)(CC)Nc1nc(NC)nc(-n2cncn2)n1 CHEMBL2402366 IC50 1.1 nM
CC(C)OCCOc1nc(Oc2ccc3c(c2)COB3O)cc(C(F)(F)F)c1C#N CHEMBL3694413 IC50 1.1 nM
[O-][n+]1ccc(CC(c2ccc(NCc3ccccc3)nc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL349635 IC50 1.2 nM
CN(Cc1ccccc1)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL354931 IC50 1.2 nM
CC(C)(O)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC3CC3)c2)cn1 CHEMBL276559 IC50 1.2 nM
CC(O)(c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1)C1CCCCC1 CHEMBL301441 IC50 1.2 nM
COc1ccc(-c2ccc3c(c2)COC3=O)n2nc(C3(C(=O)OCC(C)C)CC3)nc12 CHEMBL4747201 IC50 1.2 nM
Cc1c[n+]([O-])ccc1CC(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)c1ccc(OC(F)F)c(OC(F)F)c1 CHEMBL323312 IC50 1.3 nM
N#Cc1cc(Cl)c(Oc2ccc3c(c2)COB3O)nc1OCCOC1CC1 CHEMBL3694412 IC50 1.3 nM
CC(=O)CCCOc1nc(Oc2cc(C)c3c(c2)COB3O)c(Cl)cc1C#N CHEMBL3694417 IC50 1.3 nM
CNc1nc(NC2(C#N)CCCC2)nc(-n2cncn2)n1 CHEMBL2402360 IC50 1.4 nM
CN(Cc1ccc2ccccc2c1)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL444865 IC50 1.5 nM
COc1cccc(-c2cc(Cc3ccncc3)cc3cccnc23)c1 CHEMBL198432 IC50 1.5 nM
CC(c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)N(C(=O)c1ccc(C(C)(C)O)cc1)c1ccc(S(C)(=O)=O)cc1 CHEMBL380933 IC50 1.5 nM
COc1ccc(OC)c(-c2nnc3ccc(-c4ccc(OC)c(O[C@@H]5CCOC5)c4)nn23)c1 CHEMBL549560 IC50 1.5 nM
CCOc1cccc(-c2cccc(-n3cc(C(=O)NC(C)C)c(=O)c4cccnc43)c2)c1 CHEMBL456808 IC50 1.54 nM
CC(C)(O)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC3CCC3)c2)cc1 CHEMBL2112294 IC50 1.6 nM
COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)cc1OC1CCCC1 CHEMBL42126 IC50 1.6 nM
CC(c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)N(C(=O)C1CC1)c1ccc(S(C)(=O)=O)cc1 CHEMBL379768 IC50 1.6 nM
CNc1nc(NC2(C#N)CCC(C)CC2)nc(-n2cncn2)n1 CHEMBL2402364 IC50 1.6 nM
C[C@@H](Nc1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1)c1ccccc1 CHEMBL166299 IC50 1.7 nM
CC(c1cc(-c2cccc(/C=C(\c3ccc(S(C)(=O)=O)cc3)c3ncc(C(C)(C)O)s3)c2)c2ncccc2c1)S(C)(=O)=O CHEMBL198722 IC50 1.7 nM
CC(C)(c1cc(-c2cccc(NC(=O)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1)S(C)(=O)=O CHEMBL208236 IC50 1.7 nM
CNc1nc(NC2(C#N)CCCCC2)nc(-n2cncn2)n1 CHEMBL2402530 IC50 1.7 nM
CC(=O)CCCOc1nc(Oc2cc(F)c3c(c2)COB3O)c(Cl)cc1C#N CHEMBL3694419 IC50 1.7 nM
CC(c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)N(C(=O)c1ccc(F)cc1)c1ccc(S(C)(=O)=O)cc1 CHEMBL208382 IC50 1.8 nM
CC(C)NC(=O)N(c1ccc(S(C)(=O)=O)cc1)C(C)c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1 CHEMBL207559 IC50 1.8 nM
O=C(Nc1c(Cl)cncc1Cl)c1ccc(OC(F)F)c2c1OC1(CCSCC1)O2 CHEMBL3654386 IC50 2.0 nM
Cc1cc(Oc2nc(OCCOC(C)C)c(C#N)cc2Cl)cc2c1B(O)OC2 CHEMBL3694416 IC50 2.0 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(C3CC3)nc12 CHEMBL3676231 IC50 2.0 nM
O=C(NC1CC1)c1nn2c(c1-c1cc(F)c(Cl)cc1F)OC[C@@H](F)C2 CHEMBL4168265 IC50 2.0 nM
CC(C)(O)c1ccc(C(Cc2ccc[n+]([O-])c2)c2ccc(OC(F)F)c(OC3CC3)c2)cn1 CHEMBL78439 IC50 2.1 nM
COc1ccc([C@H](Cc2ccncc2)c2ccccc2)cc1OC1CCCC1 CHEMBL32442 IC50 2.1 nM
CC(c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)N(C(=O)c1cccnc1)c1ccc(S(C)(=O)=O)cc1 CHEMBL206592 IC50 2.1 nM
COc1ccc(C2=NN(C3CCCCCC3)C(=O)C2(C)C)cc1OCCCCOc1ccc(-c2nn[nH]n2)cc1 CHEMBL2171452 IC50 2.1 nM
CC(C)(C(=O)O)c1cccc(-c2ccc(C(Cc3cc[n+]([O-])cc3)c3ccc(OC(F)F)c(OC(F)F)c3)cc2)c1 CHEMBL35954 IC50 2.2 nM
COc1ccc(C2=NOC(C(=O)NO)C2)cc1OC1CCCC1 CHEMBL307646 IC50 2.2 nM
CC(=O)CCCOc1nc(Oc2ccc3c(c2)COB3O)cc(C(F)(F)F)c1C#N CHEMBL3694414 IC50 2.2 nM
Cc1ccc(CCNc2ccc(C(Cc3cc[n+]([O-])cc3)c3ccc(OC(F)F)c(OC(F)F)c3)cn2)cc1 CHEMBL164199 IC50 2.3 nM
CCN(Cc1ccccc1)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL164564 IC50 2.3 nM
[O-][n+]1ccc(CC(c2ccc(C(O)(c3ccccc3)C(F)(F)F)nc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL56971 IC50 2.4 nM
CCC(C)(C#N)Nc1nc(NC)nc(-n2cncn2)n1 CHEMBL2402510 IC50 2.4 nM
COc1ccc([C@H](Cc2ccncc2)c2ccc(NS(C)(=O)=O)cc2)cc1OC1CCCC1 CHEMBL285766 IC50 2.5 nM
CC(=O)c1c[n+]([O-])ccc1CC(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)c1ccc(OC(F)F)c(OC(F)F)c1 CHEMBL408345 IC50 2.7 nM
[N-]=[N+]=Nc1cccc(-c2cc(I)cc3cccnc23)c1 CHEMBL127994 IC50 2.7 nM
C#CC(CC)(CC)Nc1nc(NC)nc(-n2cncn2)n1 CHEMBL2402512 IC50 2.7 nM
COc1ccc(C(Cc2ccncc2)c2ccc(Cl)cc2)cc1OC1CCCC1 CHEMBL287348 IC50 2.8 nM
COc1ccc([C@H](Cc2ccncc2)c2ccsc2)cc1OC1CCCC1 CHEMBL286998 IC50 3.0 nM
[O-][n+]1ccc(CC(c2ccc(Cc3ccccc3)nc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL57757 IC50 3.0 nM
COc1ccc(OC)c(-c2nnc3n2N=C(c2ccc(OC)c(O[C@@H]4CCOC4)c2)CS3)c1 CHEMBL564209 IC50 3.0 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(C3(C(N)=O)CC3)nc12 CHEMBL3676247 IC50 3.0 nM
COc1ccc(C(=O)Cc2c(Cl)c[n+]([O-])cc2Cl)n2nc(C3CC3)nc12 CHEMBL3676257 IC50 3.0 nM
Cc1ccccc1C(=O)NS(=O)(=O)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL287114 IC50 3.1 nM
CC(C)(c1cc(-c2cccc(C(=O)Nc3ccncc3)c2)c2ncccc2c1)S(C)(=O)=O CHEMBL383837 IC50 3.1 nM
[N-]=[N+]=Nc1ccc(I)c(-c2cc(Cc3ccncc3)cc3cccnc23)c1 CHEMBL127201 IC50 3.3 nM
CC(C)c1cc(-c2cccc(CC(c3ccncc3)C(C)(C)O)c2)c2ncccc2c1 CHEMBL198564 IC50 3.4 nM
COc1ccc(OC)c(-c2nnc3n2N=C(c2ccc(OC)c(OC4CCOC4)c2)CS3)c1 CHEMBL562051 IC50 3.4 nM
CC(C)(c1cc(-c2cccc(C(=O)Nc3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1)S(C)(=O)=O CHEMBL208149 IC50 3.5 nM
CC(C)CNC(=O)c1cn(-c2cccc(Br)c2)c2ncccc2c1=O CHEMBL464600 IC50 3.54 nM
CNc1nc(NC2(C#N)CCCCC2)nc(-n2cccn2)n1 CHEMBL2402529 IC50 3.6 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3Cl)SC2)cc1O[C@@H]1CCOC1 CHEMBL550168 IC50 3.8 nM
CNC(=O)Nc1ccc([C@@H](Cc2ccncc2)c2ccc(OC)c(OC3CCCC3)c2)cc1 CHEMBL286119 IC50 4.0 nM
COc1ccc(C2CNC(=O)C2)cc1OC1CCCC1 CHEMBL63 IC50 4.0 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(C3(CO)CC3)nc12 CHEMBL3676236 IC50 4.0 nM
O=C(Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c2c1OCC1(CCOCC1)CO2 CHEMBL3654381 IC50 4.0 nM
[O-][n+]1ccc(CC(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL286224 IC50 4.2 nM
Cc1cc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)ccc1C(O)(C(F)(F)F)C(F)(F)F CHEMBL103635 IC50 4.4 nM
CNc1nc(NC2(C#N)CCCCC2)nc(SC)n1 CHEMBL2402520 IC50 4.4 nM
CC1(C)CCc2c(N3CCOCC3)nc3sc4c(NCc5cccnc5)ncnc4c3c2C1 CHEMBL1257536 IC50 4.5 nM
CCNC(=O)OCc1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL285247 IC50 4.6 nM
COC(=O)Cc1ccc(OCc2cc(-c3cccc(OC)c3)c3ncccc3c2)cc1 CHEMBL1224717 IC50 4.6 nM
O=C(NC1CC1)c1cn(-c2cccc(-c3ccccc3C3CC3C(=O)O)c2)c2ncccc2c1=O CHEMBL1801069 IC50 4.6 nM
CCCC(=O)Nc1ccc([C@@H](Cc2ccncc2)c2ccc(OC)c(OC3CCCC3)c2)cc1 CHEMBL286921 IC50 4.8 nM
Cc1noc(/C(=C\c2cccc(-c3cc(C(C)(C)S(C)(=O)=O)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)n1 CHEMBL198732 IC50 4.8 nM
CC1(C)CCc2c(N3CCOCC3)nc3oc4c(N(CCO)CCN5CCOCC5)ncnc4c3c2C1 CHEMBL1830638 IC50 4.8 nM
CNc1nc(NC2(C#N)CCCCC2)nc(-n2cnc(C#N)n2)n1 CHEMBL2402359 IC50 4.9 nM
COc1ccc([C@H](Cc2ccncc2)c2cccc(NC(=O)N3CCCC3)c2)cc1OC1CCCC1 CHEMBL286118 IC50 5.0 nM
COc1ccc([C@H](Cc2ccncc2)c2ccoc2)cc1OC1CCCC1 CHEMBL33419 IC50 5.0 nM
COc1ccc([C@H](Cc2ccncc2)c2ccc(O)cc2)cc1OC1CCCC1 CHEMBL35391 IC50 5.0 nM
CC1(C)Cc2c(c(N3CCOCC3)nc3sc4c(N(CCN5CCOCC5)Cc5cccnc5)ncnc4c23)CO1 CHEMBL1255772 IC50 5.0 nM
CCNc1nc2oc3c(NCCN4CCOCC4)ncnc3c2c2c1CCC(C)(C)C2 CHEMBL1830641 IC50 5.0 nM
CCNc1nc2oc3c(NCCCN4CCCC4=O)ncnc3c2c2c1CCC(C)(C)C2 CHEMBL1830644 IC50 5.0 nM
O=C(Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c2c1OC1(CCOCC1)O2 CHEMBL3654383 IC50 5.0 nM
O=C(NC1CC1)c1cn(-c2cccc(C#Cc3ccc[n+]([O-])c3)c2)c2ncccc2c1=O CHEMBL485629 IC50 5.1 nM
CC(C)OCCOc1nc(Oc2ccc3c(c2)COB3O)c(Cl)cc1C#N CHEMBL3694409 IC50 5.2 nM
CC1(C)CCc2c(-c3ccco3)nc3sc4c(NCCN5CCOCC5)ncnc4c3c2C1 CHEMBL1257188 IC50 5.4 nM
O=S(=O)(Nc1cccc(-c2cc(Cc3ccncc3)cc3cccnc23)c1)c1ccccc1 CHEMBL370220 IC50 5.6 nM
O=C(O)Cc1ccc(OCc2cc(-c3cccc(OC(F)F)c3)c3ncccc3c2)cc1 CHEMBL1223687 IC50 5.7 nM
CN(CCc1ccccc1)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL351007 IC50 5.8 nM
[O-][n+]1ccc(CC(c2ccc(C(O)c3ccccc3)nc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL56330 IC50 6.0 nM
CC(O)(c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1)c1nccs1 CHEMBL56575 IC50 6.0 nM
CCCCC(C)(O)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL57131 IC50 6.0 nM
O=C(Cc1c(Cl)cncc1Cl)c1ccc(OC(F)F)c2c1OCC1(COC1)CO2 CHEMBL3654378 IC50 6.0 nM
O=C(Cc1c(Cl)cncc1Cl)c1ccc(OC(F)F)c2c1OCC1(CCOCC1)CO2 CHEMBL3654380 IC50 6.0 nM
COc1ccc(OC)c(-c2nnc3n2N=C(c2ccc(OC)c(OCC4CC4)c2)CS3)c1 CHEMBL559384 IC50 6.1 nM
CC(C)(O)c1ccc(-c2cccc(-n3cc(C(=O)NC4CC4)c(=O)c4cccnc43)c2)c[n+]1[O-] CHEMBL485620 IC50 6.2 nM
CCNc1nc2oc3c(NCc4cccnc4)ncnc3c2c2c1CCC(C)(C)C2 CHEMBL1830790 IC50 6.2 nM
CC1(C)CCc2c(N3CCOCC3)nc3sc4c(N(CCO)CCN5CCOCC5)ncnc4c3c2C1 CHEMBL1255597 IC50 6.4 nM
CCCC(C#N)(CCC)Nc1nc(NC)nc(-n2cncn2)n1 CHEMBL2402365 IC50 6.5 nM
CC(C)OCCOc1nc(Oc2ccc3c(c2)COB3O)c(C#N)cc1C#N CHEMBL3694415 IC50 6.5 nM
CNc1nc(NC2(C#N)CCCCC2)nc(-n2ccnc2)n1 CHEMBL2402527 IC50 6.6 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3C(F)(F)F)SC2)cc1O[C@@H]1CCOC1 CHEMBL564063 IC50 6.7 nM
COc1ccc(OC)c(-c2nnc3n2N=C(c2ccc(OC)c(OC)c2)CS3)c1 CHEMBL252387 IC50 6.7 nM
CC(C)Cc1nc2sc3c(NCCN4CCOCC4)ncnc3c2c2c1CCC(C)(C)C2 CHEMBL1258922 IC50 6.7 nM
COc1ccc([C@H](Cc2ccncc2)c2ccc(NS(=O)(=O)c3ccccc3)cc2)cc1OC1CCCC1 CHEMBL36559 IC50 7.0 nM
COc1ccc([C@H](Cc2ccncc2)c2ccc(NS(=O)(=O)C(C)C)cc2)cc1OC1CCCC1 CHEMBL35011 IC50 7.0 nM
COc1ccc([C@H](Cc2cc[n+]([O-])cc2)c2ccccc2)cc1OC1CCCC1 CHEMBL286603 IC50 7.0 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(-c3ccco3)nc12 CHEMBL3676233 IC50 7.0 nM
O=C(Cc1c(Cl)cncc1Cl)c1ccc(OC(F)F)c2c1OC1(CCOCC1)O2 CHEMBL3654382 IC50 7.0 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3C(F)(F)F)SC2)cc1OC1CCOC1 CHEMBL564735 IC50 7.1 nM
Cc1ccc(C(=O)c2ccc(C(Cc3cc[n+]([O-])cc3)c3ccc(OC(F)F)c(OC(F)F)c3)cc2)nc1 CHEMBL36242 IC50 7.3 nM
COc1ccc(OC)c(-c2nnc3ccc(-c4ccc(OC)c(O[C@H]5CCOC5)c4)nn23)c1 CHEMBL562050 IC50 7.3 nM
COc1ccc([C@H](Cc2ccncc2)c2ccc(NS(=O)(=O)c3c(F)c(F)c(F)c(F)c3F)cc2)cc1OC1CCCC1 CHEMBL286421 IC50 7.5 nM
[O-][n+]1ccc(CC(c2ccc(C3(O)CCC3)cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL266000 IC50 7.5 nM
O=C(Cc1ccccc1)Nc1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL423252 IC50 7.8 nM
COc1cccc(COc2cc(C(=O)O)cc(N3CC(c4ccc(OC)c(OC5CCCC5)c4)CC3=O)c2)c1 CHEMBL322092 Log IC50 7.9 nM
COc1ccc(C(Cc2ccncc2)c2cccc(F)c2)cc1OC1CCCC1 CHEMBL284386 IC50 8.0 nM
COc1ccc([C@H](Cc2ccncc2)c2ccc(NS(=O)(=O)Cc3ccccc3)cc2)cc1OC1CCCC1 CHEMBL287359 IC50 8.0 nM
COc1ccc([C@H](Cc2ccncc2)c2ccncc2)cc1OC1CCCC1 CHEMBL36007 IC50 8.0 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(C3(CNCc4ccccc4)CC3)nc12 CHEMBL3676248 IC50 8.0 nM
COc1cccc(COc2cccc(N3CC(c4ccc(OC)c(OC5CCCC5)c4)CC3=O)c2)c1 CHEMBL320307 Log IC50 8.2 nM
CCNC(=O)Nc1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL166245 IC50 8.3 nM
CN(C)C(=O)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL35350 IC50 8.6 nM
COc1cccc(COc2cc(C(=O)NN(C)C)cc(N3CC(c4ccc(OC)c(OC5CCCC5)c4)CC3=O)c2)c1 CHEMBL326655 Log IC50 8.6 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3F)SC2)cc1O[C@@H]1CCOC1 CHEMBL550782 IC50 8.6 nM
COc1ccc([C@H](Cc2ccncc2)c2ccc(N(S(C)(=O)=O)S(C)(=O)=O)cc2)cc1OC1CCCC1 CHEMBL416399 IC50 9.0 nM
c1ccc(-c2cc(Cn3ccnc3)cc3cccnc23)cc1 CHEMBL419416 IC50 9.0 nM
CC1(C)CCc2c(-c3ccoc3)nc3sc4c(NCCN5CCOCC5)ncnc4c3c2C1 CHEMBL1257189 IC50 9.0 nM
CC(C)NC(=O)c1cn(-c2cccc(Br)c2)c2ncccc2c1=O CHEMBL456172 IC50 9.2 nM
CC(C)N(Cc1ccccc1)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL166297 IC50 9.3 nM
CC(C)(O)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL289023 IC50 9.6 nM
COc1ccc(C2=NOC(C)(C(=O)NO)C2)cc1OC1CCCC1 CHEMBL91551 IC50 9.8 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3Cl)SC2)cc1OC1CCOC1 CHEMBL564003 IC50 9.8 nM
COc1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1 CHEMBL1224653 IC50 9.9 nM
COc1ccc([C@H](Cc2ccncc2)c2ccc(NC(=O)N3CCCC3)cc2)cc1OC1CCCC1 CHEMBL289012 IC50 10.0 nM
CC(=O)N(c1ccc(S(C)(=O)=O)cc1)C(C)c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1 CHEMBL204522 IC50 10.0 nM
CCN(CC)C(=O)Nc1ccc([C@@H](Cc2ccncc2)c2ccc(OC)c(OC3CCCC3)c2)cc1 CHEMBL285488 IC50 11.0 nM
FC(F)Oc1ccc(C(Cc2ccncc2)c2ccc(Cl)cc2)cc1OC(F)F CHEMBL285895 IC50 11.0 nM
CCc1nn(C2CCCC2)c2c1CCn1c-2nnc1C(C)(C)C CHEMBL218103 IC50 11.0 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3F)SC2)cc1OC1CCOC1 CHEMBL559461 IC50 11.0 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3OC)SC2)cc1O[C@@H]1CCOC1 CHEMBL563176 IC50 11.0 nM
COc1ccc(OC)c(-c2nnc3n2N=C(c2ccc(OC(F)F)c(OCC4CC4)c2)CS3)c1 CHEMBL550294 IC50 11.0 nM
CC(C)=CCn1nc(-c2cccc([N+](=O)[O-])c2)c2ncccc2c1=O CHEMBL2158056 IC50 11.0 nM
CC(C)c1cc(-c2cccc(C(Cc3ccncc3)c3ccc(Cl)cc3)c2)c2ncccc2c1 CHEMBL382545 IC50 11.8 nM
COc1ccc([C@H](Cc2ccncc2)c2cccc(NS(=O)(=O)N(C)C)c2)cc1OC1CCCC1 CHEMBL287167 IC50 12.0 nM
CC(C)Nc1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL163311 IC50 12.0 nM
CNc1nc(NC2(C#N)CCCCC2)nc(-n2cnc3ccccc32)n1 CHEMBL2402528 IC50 12.0 nM
Cc1cc(C#N)c(F)cc1-c1c(C(=O)NC2CC2)nn2c1OCC(F)C2 CHEMBL4176593 IC50 12.0 nM
CS(=O)(=O)c1ccc(OCc2cc(-c3cccc(OC(F)F)c3)c3ncccc3c2)cc1 CHEMBL1223686 IC50 12.8 nM
FC(F)Oc1ccc(C(Cc2ccncc2)c2ccc(Cl)cc2)cc1OC1CCCC1 CHEMBL35234 IC50 13.0 nM
COc1cc(F)c(C(Cc2ccncc2)c2ccc(Cl)cc2)cc1OC1CCCC1 CHEMBL35672 IC50 13.0 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3C(F)(F)F)SC2)cc1OC CHEMBL550981 IC50 13.0 nM
COc1ccc(OC)c(-c2nnc3n2N=C(c2ccc(OC)c(OC4CCCC4)c2)CS3)c1 CHEMBL551783 IC50 13.0 nM
O=C(Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c2c1OCC1(COC1)CO2 CHEMBL3654379 IC50 13.0 nM
O=C(Cc1c(Cl)cncc1Cl)c1ccc(OC(F)F)c2c1OC1(CCS(=O)(=O)CC1)O2 CHEMBL3654385 IC50 13.0 nM
O=C(c1ccccc1)c1cc(-c2cccc(I)c2)c2ncccc2c1 CHEMBL123576 IC50 15.0 nM
CC(C)NC(=O)N(Cc1cc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)ccc1Cl)c1ccc(S(C)(=O)=O)cc1 CHEMBL207424 IC50 15.0 nM
CC(C)NC(=O)c1cn(-c2ccccc2)c2ncccc2c1=O CHEMBL456173 IC50 15.3 nM
CCN(C)C(=O)Nc1cccc([C@@H](Cc2ccncc2)c2ccc(OC)c(OC3CCCC3)c2)c1 CHEMBL287026 IC50 16.0 nM
O=S(=O)(Nc1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1)c1ccccc1 CHEMBL162870 IC50 16.0 nM
[O-][n+]1ccc(CC(c2ccc(C3(O)CC3)cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL35440 IC50 16.0 nM
CC(C)(c1cc(-c2cccc(C(=O)Nc3ccccc3)c2)c2ncccc2c1)S(C)(=O)=O CHEMBL207775 IC50 16.0 nM
O=C(Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c2c1OC1(CCS(=O)(=O)CC1)O2 CHEMBL3654384 IC50 16.0 nM
CC1(C)CCc2c(N3CCOCC3)nc3oc4c(NCCN5CCOCC5)ncnc4c3c2C1 CHEMBL1830636 IC50 16.3 nM
COc1ccc(C(Cc2ccncc2)c2ccc(OC)c(OC3CCCC3)c2)cc1 CHEMBL287307 IC50 17.0 nM
O=C(NC1(O)CC1)c1cn(-c2cccc(-c3ccc(C4CC4C(=O)O)cc3)c2)c2ncccc2c1=O CHEMBL1801153 IC50 17.0 nM
O=c1c2cccnc2n(-c2cccc([N+](=O)[O-])c2)c(=O)n1Cc1ccncc1 CHEMBL1232082 EC50 17.0 nM
COc1ccc(C(Cc2ccncc2)c2ccccc2)cc1OC1CCCC1 CHEMBL286334 IC50 17.5 nM
CC(C)(C)N(Cc1ccccc1)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL350627 IC50 18.0 nM
Cc1cc(CC(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc[n+]1[O-] CHEMBL105164 IC50 18.0 nM
CNc1nc2sc3c(NCCN4CCOCC4)ncnc3c2c2c1CCC(C)(C)C2 CHEMBL1258806 IC50 18.0 nM
CC1(C)CCc2c(N3CCOCC3)nc3sc4c(NCCCN5CCCC5=O)ncnc4c3c2C1 CHEMBL1257421 IC50 18.0 nM
CNc1nc(NC2(C#N)CCCCC2)nc(N(C)C)n1 CHEMBL2402525 IC50 18.0 nM
CNC(=O)Nc1cccc([C@@H](Cc2ccncc2)c2ccc(OC)c(OC3CCCC3)c2)c1 CHEMBL287377 IC50 19.0 nM
CC1(C)CCc2c(N3CCOCC3)nc3sc4c(NCc5ccncc5)ncnc4c3c2C1 CHEMBL1257654 IC50 19.0 nM
CNc1nc(NC2(C#N)CCCCC2)nc(OC)n1 CHEMBL2402519 IC50 19.0 nM
CNc1nc(NC2(C#N)CCCCC2)nc(C2CC2)n1 CHEMBL2402517 IC50 19.0 nM
CC(C)OCCOc1nc(Oc2cc(F)c3c(c2)COB3O)c(Cl)cc1C#N CHEMBL3694418 IC50 19.0 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3OC)SC2)cc1OC1CCOC1 CHEMBL564936 IC50 20.0 nM
CN(C)c1nc2sc3c(NCCN4CCOCC4)ncnc3c2c2c1COC(C)(C)C2 CHEMBL1258807 IC50 20.0 nM
CC1(C)CCc2c(N3CCOCC3)nc3oc4c(NCc5cccnc5)ncnc4c3c2C1 CHEMBL1830635 IC50 20.0 nM
O=C(O)c1ccc(-c2cc3cccnc3c(-c3cccc([N+](=O)[O-])c3)n2)cc1 CHEMBL74078 EC50 20.0 nM
Cc1cc(Cl)ccc1-c1c(C(=O)NC2CC2)nn2c1OCC(F)C2 CHEMBL4164367 IC50 20.6 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3Cl)SC2)cc1OCC1CC1 CHEMBL560308 IC50 21.0 nM
COc1ccc([C@H](Cc2ccncc2)c2cccc(NC(N)=O)c2)cc1OC1CCCC1 CHEMBL33021 IC50 22.0 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3Cl)SC2)cc1OC CHEMBL565085 IC50 22.0 nM
CCN(C)c1nc2oc3c(NCc4cccnc4)ncnc3c2c2c1CCC(C)(C)C2 CHEMBL1830647 IC50 22.0 nM
O=C(c1ccccc1)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL57095 IC50 23.0 nM
CCc1nn(C2CCCC2)c2c1CCn1c(-c3cccs3)nnc1-2 CHEMBL217899 IC50 23.0 nM
CC1(C)Cc2c(c(N3CCOCC3)nc3sc4c(N(CCO)CCN5CCOCC5)ncnc4c23)CO1 CHEMBL1257778 IC50 23.0 nM
COCC(COc1nc(Oc2ccc3c(c2)COB3O)c(Cl)cc1C#N)OC CHEMBL3694411 IC50 23.0 nM
O=C(O)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL32153 IC50 24.0 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3OC)SC2)cc1OC CHEMBL251785 IC50 24.0 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(C3(C(=O)N4CCOCC4)CC3)nc12 CHEMBL3676239 IC50 24.0 nM
COc1ccc(-c2ccc(-c3ccccn3)o2)cc1OC1CCCC1 CHEMBL322545 IC50 25.0 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3Cl)SC2)cc1OC1CCCC1 CHEMBL563512 IC50 26.0 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(COCc3ccccc3)nc12 CHEMBL3676234 IC50 26.0 nM
CCN(CC)C(=O)Nc1cccc([C@@H](Cc2ccncc2)c2ccc(OC)c(OC3CCCC3)c2)c1 CHEMBL416045 IC50 27.0 nM
CCc1c[n+]([O-])ccc1CC(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)c1ccc(OC(F)F)c(OC(F)F)c1 CHEMBL103859 IC50 27.0 nM
CSc1cccc(-c2nc([C@H]3CC[C@H](C(=O)O)CC3)cc3cccnc23)c1 CHEMBL2172376 IC50 27.0 nM
COc1ccc(C(=O)NCC(=O)NO)cc1OC1CCCC1 CHEMBL91571 IC50 27.2 nM
[N-]=[N+]=Nc1cc(-c2cccc(I)c2)c2ncccc2c1 CHEMBL124575 IC50 28.0 nM
CCN(C)c1nc2oc3c(NCCN4CCOCC4)ncnc3c2c2c1CCC(C)(C)C2 CHEMBL1830642 IC50 28.0 nM
CCc1nc(-c2cc(OCC3CC3)cc(OCC3CC3)c2)c2cc(OC)c(OCCO)cc2n1 CHEMBL97817 IC50 30.0 nM
CC[C@H]1OC(=O)[C@H](C)[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C(=O)N3CCOCC3)[C@H]2O)[C@](C)(OC)C[C@@H](C)C(=O)[C@H](C)C2N(CCCOc3cc(C(=O)Nc4c(Cl)cncc4Cl)ccc3OC)C(=O)O[C@@]21C CHEMBL3650150 IC50 30.0 nM
CCCCCCCCCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]1C(=O)NCC(=O)N[C@@H](CCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@H](CO)C(=O)N[C@@H]([C@H](C)CC(=O)O)C(=O)N[C@@H](CC(=O)c2ccccc2N)C(=O)O[C@@H]1C CHEMBL4744444 AC50 30.0 nM
COc1ccc([C@H](Cc2ccncc2)c2cccc(NC(=O)NC(C)C)c2)cc1OC1CCCC1 CHEMBL289453 IC50 31.0 nM
[O-][n+]1ccc(CC(c2ccc(N3CCCC3)nc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL164800 IC50 31.0 nM
Nc1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL165298 IC50 31.0 nM
O=C(c1nn2c(c1-c1cc(F)c(Cl)cc1F)OCCC2)N1CCC1 CHEMBL4168448 IC50 31.9 nM
[O-][n+]1cc(C(Cc2ccncc2)c2ccc(Cl)cc2)cc(OC(F)F)c1OC(F)F CHEMBL284852 IC50 32.0 nM
Cc1cc(C(O)(C(F)(F)F)C(F)(F)F)ccc1C(Cc1cc[n+]([O-])cc1)c1ccc(OC(F)F)c(OC(F)F)c1 CHEMBL102718 IC50 32.0 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3OC)SC2)cc1OC1CCCC1 CHEMBL562566 IC50 32.0 nM
CC(C)(C)NC(=O)c1cn(-c2cccc(-c3ccc(C4CC4C(=O)O)cc3)c2)c2ncccc2c1=O CHEMBL1801152 IC50 32.0 nM
CC(=O)Nc1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL165773 IC50 33.0 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3F)SC2)cc1OC1CCCC1 CHEMBL563585 IC50 33.0 nM
CC(C)(O)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL417776 IC50 35.0 nM
COc1ccc(C2CC(=O)N(Cc3cc(I)cc(C4(C(F)(F)F)N=N4)c3)C2)cc1OC1CCCC1 CHEMBL126587 IC50 35.0 nM
CCc1nn(C2CCCC2)c2c1CCn1c(-c3ccccc3Cl)nnc1-2 CHEMBL218653 IC50 35.0 nM
COc1ccccc1-c1nnc2n1N=C(c1ccc(OC(F)F)c(OCC3CC3)c1)CS2 CHEMBL552388 IC50 35.0 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3OC)SC2)cc1OCC1CC1 CHEMBL560906 IC50 35.0 nM
CC1(C)CCc2c(NCCO)nc3oc4c(NCc5cccnc5)ncnc4c3c2C1 CHEMBL1830640 IC50 36.0 nM
FC(F)Oc1ccc(C2=Nn3c(nnc3-c3ccccc3Cl)SC2)cc1OCC1CC1 CHEMBL562729 IC50 37.0 nM
COc1ccc([C@]2(C#N)CC[C@@H](C(=O)O)CC2)cc1OC1CCCC1 CHEMBL511115 IC50 38.0 nM
[O-][n+]1ccc(CC(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)c2ccc(OC(F)F)c(OC(F)F)c2)c(CO)c1 CHEMBL105243 IC50 38.0 nM
O=S(=O)(CCCOCCc1ccccc1)CCNCCc1ccc(O)c2nc(O)sc12 CHEMBL82663 IC50 38.0 nM
CNc1nc(NC2(C#N)CCCCC2)nc(N2CCCC2)n1 CHEMBL2402526 IC50 38.0 nM
CNc1nc(C#N)nc(NC2(C#N)CCCCC2)n1 CHEMBL2402518 IC50 38.0 nM
CC(c1cc[n+]([O-])cc1)C(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)c1ccc(OC(F)F)c(OC(F)F)c1 CHEMBL102784 IC50 39.0 nM
COc1ccc(C(Cc2ccncn2)c2ccccc2)cc1OC1CCCC1 CHEMBL284506 IC50 40.0 nM
COc1ccc(C(Cc2cncn2C)c2ccccc2)cc1OC1CCCC1 CHEMBL35218 IC50 40.0 nM
CNc1nc(Cl)nc(NC2(C#N)CCCCC2)n1 CHEMBL2402532 IC50 40.0 nM
CC(O)c1c[n+]([O-])ccc1CC(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)c1ccc(OC(F)F)c(OC(F)F)c1 CHEMBL319858 IC50 42.0 nM
CC1(C)CCc2c(N3CCCC3)nc3sc4c(NCCN5CCOCC5)ncnc4c3c2C1 CHEMBL1258470 IC50 43.0 nM
[O-][n+]1ccc(CC(c2ccc(CO)cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL285500 IC50 44.0 nM
COc1ccc(-c2ccc(-c3ccc(OC)c(OC4CCCC4)c3)o2)cc1OC1CCCC1 CHEMBL111506 IC50 44.0 nM
CNc1nc(Cl)nc(NC2(C#N)CCCCCC2)n1 CHEMBL2402534 IC50 44.0 nM
CC(O)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL286392 IC50 45.0 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3C(F)(F)F)SC2)cc1OC1CCCC1 CHEMBL559976 IC50 45.0 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(C)nc12 CHEMBL3676237 IC50 45.0 nM
COc1ccc(NC(=O)c2cnc(SC)nc2N2CCOCC2)cc1OC CHEMBL4284354 IC50 45.0 nM
COc1ccc(C(=O)Cc2ccccc2Cl)n2nc(C3CC3)nc12 CHEMBL3676256 IC50 46.0 nM
COc1ccc(C(Cc2ccncc2)c2ccc(F)cc2)cc1OC1CCCC1 CHEMBL36077 IC50 47.0 nM
[O-][n+]1cccc(C[C@H](c2ccc(OC(F)F)c(OC3CC3)c2)c2cnc(C(O)(C(F)(F)F)C(F)(F)F)s2)c1 CHEMBL383762 IC50 48.0 nM
CC1(C)Cc2c(c(N3CCOCC3)nc3sc4c(NCc5cccnc5)ncnc4c23)CO1 CHEMBL1257422 IC50 48.0 nM
COc1ccc(C(=O)NC(C)C(=O)NO)cc1OC1CCCC1 CHEMBL90375 IC50 50.7 nM
CC(C)c1cc(-c2cccc(C(Cc3cc[n+]([O-])cc3)c3ccc(Cl)cc3)c2)c2ncccc2c1 CHEMBL198464 IC50 52.0 nM
COc1ccc(C(=O)Cc2ccncc2Br)n2nc(C3(CO)CC3)nc12 CHEMBL3676253 IC50 52.0 nM
O=C(O)Cc1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 CHEMBL418231 IC50 53.0 nM
Fc1ccccc1-c1nnc2n1N=C(c1ccc(OC(F)F)c(OCC3CC3)c1)CS2 CHEMBL564568 IC50 53.0 nM
CC(C)C(=O)c1c(C(C)C)nn2ccccc12 CHEMBL19449 IC50 54.0 nM
CNc1nc(Cl)nc(NC2(C#N)CCCC2)n1 CHEMBL2402533 IC50 54.0 nM
CCCNC(=O)Nc1cccc([C@@H](Cc2ccncc2)c2ccc(OC)c(OC3CCCC3)c2)c1 CHEMBL32427 IC50 54.6 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(C3(C(=O)O)CC3)nc12 CHEMBL3676238 IC50 55.0 nM
N#Cc1ccc(Oc2ccc3c(c2)COB3O)cc1 CHEMBL484785 IC50 55.0 nM
CNc1nc(Nc2ccccc2)nc(NC2(C#N)CCCCC2)n1 CHEMBL2402524 IC50 56.0 nM
Cc1c[n+]([O-])cc(C)c1CC(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)c1ccc(OC(F)F)c(OC(F)F)c1 CHEMBL318108 IC50 57.0 nM
COc1cccc(C(Cc2ccncc2)c2ccc(OC)c(OC3CCCC3)c2)c1 CHEMBL445833 IC50 58.0 nM
O=C(O)c1ccc(-c2cc3cccnc3c(-c3cccc(Cl)c3)n2)cc1 CHEMBL161115 IC50 59.0 nM
CNc1nc(NC2CCCC2)nc(NC2(C#N)CCCCC2)n1 CHEMBL2402523 IC50 59.0 nM
CCCC(C#N)(CCC)Nc1nc(Cl)nc(NC)n1 CHEMBL2402535 IC50 60.0 nM
N#CCCc1ccc(OCc2cc(-c3cccc(OC(F)F)c3)c3ncccc3c2)cc1 CHEMBL1223685 IC50 60.4 nM
CCN(C)c1nc2oc3c(NCCCN4CCCC4=O)ncnc3c2c2c1CCC(C)(C)C2 CHEMBL1830645 IC50 62.0 nM
CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2Nc2ccccc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3769414 Ki 62.0 nM
CC1(C)Cc2c(c(N3CCOCC3)nc3sc4c(NCCN5CCOCC5)ncnc4c23)CO1 CHEMBL1258123 IC50 63.0 nM
CC(C)(O)CCc1ccc(OCc2cc(-c3cccc(OC(F)F)c3)c3ncccc3c2)cc1 CHEMBL1221434 IC50 63.7 nM
COc1ccc(/C=N/N(C)C(=O)c2ccc(O)cc2)cc1OC CHEMBL2172710 IC50 64.0 nM
COc1ccc(-c2ccc(-c3ccncc3)o2)cc1OC1CCCC1 CHEMBL326921 IC50 65.0 nM
CN1C(=O)c2c(nn(Cc3ccc(S(C)(=O)=O)cc3)c2Nc2ccccc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3770585 Ki 65.0 nM
Cc1ccc(-n2cc(C(=O)NC(C)C)c(=O)c3cccnc32)cc1Br CHEMBL511368 IC50 66.5 nM
COc1ccccc1CNc1ncnc2c1sc1nc(N3CCOCC3)c3c(c12)CC(C)(C)OC3 CHEMBL1257655 IC50 67.0 nM
COc1ccc([C@H](Cc2ccncc2)c2ccc(Cl)cc2)cc1OC1CCCC1 CHEMBL286294 IC50 68.0 nM
COc1ccc(C(=O)Cc2c(Br)cncc2Br)n2nc(C3(CO)CC3)nc12 CHEMBL3676252 IC50 68.0 nM
COc1cc2c(-c3cc(OCC4CC4)cc(OCC4CC4)c3)nc(OCCO)nc2cc1OCCO CHEMBL98662 IC50 70.0 nM
CS(=O)(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911579 IC50 73.0 nM
CC1(C)CCc2c(N3CCOCC3)nc3sc4c(NCCN5CCOCC5)ncnc4c3c2C1 CHEMBL1258124 IC50 74.0 nM
O=C(Nc1cccnc1)c1ccc(OC(F)F)c(OCC2CC2)c1 CHEMBL3884224 IC50 76.0 nM
CC(C)(c1cc(-c2cccc(C(N)=O)c2)c2ncccc2c1)S(C)(=O)=O CHEMBL210840 IC50 78.0 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3C(F)(F)F)SC2)cc1OCC1CC1 CHEMBL557090 IC50 80.0 nM
CCOc1nc(-c2cc(OCC3CC3)cc(OCC3CC3)c2)c2cc(OC)c(OCCO)cc2n1 CHEMBL97214 IC50 85.0 nM
CCC(C#N)(CC)Nc1nc(Cl)nc(NC)n1 CHEMBL2402531 IC50 87.0 nM
COc1ccc(-c2nc(C(F)(F)F)ncc2C(=O)Nc2c(Cl)cncc2Cl)cc1OC CHEMBL4278921 IC50 89.0 nM
NC(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911576 IC50 90.0 nM
COc1ccc(C2=Nn3c(nnc3-c3ccccc3F)SC2)cc1OC CHEMBL559777 IC50 95.0 nM
O=C(Nc1ccccc1Cl)c1ccc(OC(F)F)c(OC2CCCC2)c1 CHEMBL3883753 IC50 95.0 nM
Cc1nc2sc3c(NCCN4CCOCC4)ncnc3c2c2c1CCC(C)(C)C2 CHEMBL1258921 IC50 97.0 nM
CC1(C)Cc2c(c(N3CCOCC3)nc3sc4c(NCc5ccncc5)ncnc4c23)CO1 CHEMBL1257537 IC50 97.0 nM
COc1ccc(-c2nc(C(F)(F)F)ncc2C(=O)Nc2ccncc2)cc1OC CHEMBL4282274 IC50 98.0 nM
COc1ccc(NC(=O)c2cnc(C(F)(F)F)nc2N2CCOCC2)cc1OC CHEMBL4295242 IC50 100.0 nM
COc1ccc([C@H](Cc2ccncc2)c2cccc(OCc3ccccc3)c2)cc1OC1CCCC1 CHEMBL35703 IC50 102.0 nM
CC(=O)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 CHEMBL57767 IC50 102.0 nM
COC(=O)c1ccc(OCC(C)(C)c2nc3c(N)ncn(Cc4ccc(OC)c(OC5CCCC5)c4)c-3n2)cc1 CHEMBL362175 Ki 103.0 nM
CNc1nc(Cl)nc(NC2CCCCC2)n1 CHEMBL2402542 IC50 104.0 nM
O=C(Nc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c2c1OC1(CCS(=O)(=O)CC1)O2 CHEMBL3654387 IC50 106.0 nM
C[C@@H](NC(=O)c1cccnc1Oc1ccc(F)cc1)c1cccs1 CHEMBL204449 IC50 107.0 nM
O=C(O)[C@H]1CC[C@H](c2cc3cccnc3c(-c3cccc(OC(F)(F)F)c3)n2)CC1 CHEMBL2172373 IC50 107.0 nM
COc1ccc(C(Cc2ccncc2)c2ccc(Cl)cc2)c(F)c1OC1CCCC1 CHEMBL284479 IC50 110.0 nM
CCCCNC(=O)Nc1cccc([C@@H](Cc2ccncc2)c2ccc(OC)c(OC3CCCC3)c2)c1 CHEMBL35346 IC50 113.0 nM
COc1ccc(OCC(C)(C)c2nc3c(N)ncn(Cc4ccc(OC)c(OC5CCCC5)c4)c-3n2)cc1 CHEMBL368696 Ki 113.0 nM
O=C(NC1CC1)c1nn2c(c1-c1ccnc(OC(F)F)c1)OCCC2 CHEMBL4163945 IC50 115.0 nM
O=C(Nc1cccnc1)c1ccc(OC(F)F)c(OC2CCCC2)c1 CHEMBL3885161 IC50 117.0 nM
COc1ccc(-c2cc(C(C)=O)c(-c3ccc(OC)c(OC)c3)o2)cc1OC CHEMBL109899 IC50 120.0 nM
O=[N+]([O-])c1cccc(-c2nc(-c3cccnc3)cc3cccnc23)c1 CHEMBL351613 IC50 120.0 nM
COc1cccc(-c2cc(COc3ccc(CCC#N)cc3)cc3cccnc23)c1 CHEMBL1224721 IC50 122.0 nM
O=C(O)[C@H]1CC[C@H](c2cc3cccnc3c(-c3cccc(F)c3)n2)CC1 CHEMBL2172374 IC50 123.0 nM
COc1ccc(Cn2cnc(N)c3nc(C(C)(C)COc4ccc(Cl)cc4)nc2-3)cc1OC1CCCC1 CHEMBL180015 Ki 126.0 nM
COc1cccc(-c2cc(COc3ccccc3Cl)cc3cccnc23)c1 CHEMBL1224718 IC50 126.0 nM
N#CC1(Nc2nc(Cl)nc(NC3CC3)n2)CCCCC1 CHEMBL2402514 IC50 126.0 nM
O=C(Nc1ccccc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1 CHEMBL3884788 IC50 126.0 nM
COc1nc(-c2cc(OCC3CC3)cc(OCC3CC3)c2)c2cc(OC)c(OCCO)cc2n1 CHEMBL420454 IC50 130.0 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2ncnc12 CHEMBL3676232 IC50 134.0 nM
COc1ccc([C@H](Cc2ccncc2)c2cccc(NC(=O)NC(C)(C)C)c2)cc1OC1CCCC1 CHEMBL433828 IC50 137.0 nM
COc1ccccc1OCC(C)(C)c1nc2c(N)ncn(Cc3ccc(OC)c(OC4CCCC4)c3)c-2n1 CHEMBL360527 Ki 137.0 nM
N#Cc1cccc(-c2nc(-c3ccc(C(=O)O)cc3)cc3cccnc23)c1 CHEMBL161740 IC50 140.0 nM
NC(=O)c1cn(-c2cccc(Br)c2)c2ncccc2c1=O CHEMBL464803 IC50 141.0 nM
COc1ccc(Cn2cnc(N)c3nc(C(C)(C)COc4ccc(OCC=O)c(OCC=O)c4)nc2-3)cc1OC1CCCC1 CHEMBL367846 Ki 147.0 nM
COc1ccc([C@@H](Cc2ccncc2)c2ccccc2)cc1OC1CCCC1 CHEMBL36471 IC50 148.0 nM
C#CC1(Nc2nc(Cl)nc(NC)n2)CCCCC1 CHEMBL2402536 IC50 149.0 nM
CNc1nc(NC)nc(NC2(C#N)CCCCC2)n1 CHEMBL2402522 IC50 153.0 nM
COc1ccc(Cn2cnc(N)c3nc(C(C)(C)COc4ccc(C(N)=O)cc4)nc2-3)cc1OC1CCCC1 CHEMBL178801 Ki 155.0 nM
CNC(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911578 IC50 156.0 nM
CCC(C)(CC)Nc1nc(Cl)nc(NC)n1 CHEMBL2402541 IC50 156.0 nM
COc1ccc(C(Cc2ccncc2)c2ccccc2F)cc1OC1CCCC1 CHEMBL35607 IC50 158.0 nM
COc1ccc(C(=O)N(C)/N=C/c2ccc(OC)c(OC)c2)cc1 CHEMBL2172734 IC50 159.0 nM
N#Cc1cccc(-c2nc([C@H]3CC[C@H](C(=O)O)CC3)cc3cccnc23)c1 CHEMBL2172375 IC50 160.0 nM
CNc1nc(Cl)nc(NC(C)(C)C#N)n1 CHEMBL2402540 IC50 160.0 nM
CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2Nc2ccccc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3770459 Ki 160.0 nM
CC(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911575 IC50 161.0 nM
COc1ccc([C@@H]2CNC(=O)C2)cc1OC1CCCC1 CHEMBL430893 IC50 162.0 nM
Clc1ncnc2ccccc12 CHEMBL2172707 IC50 162.0 nM
CONc1nc(Cl)nc(NC2(C#N)CCCCC2)n1 CHEMBL2402513 IC50 165.0 nM
COc1ccc(Cn2cnc(N)c3nc(C(C)(C)COc4ccc(Cl)c(Cl)c4)nc2-3)cc1OC1CCCC1 CHEMBL433774 Ki 166.0 nM
CCOc1cccc(-c2cc(COc3ccc(CCC#N)cc3)cc3cccnc23)c1 CHEMBL1223621 IC50 166.0 nM
COc1ccc(C(Cc2cccnc2)c2ccccc2)cc1OC1CCCC1 CHEMBL284973 IC50 172.0 nM
COc1ccc(Cn2cnc(N)c3nc(C(C)(C)COc4ccc(C(C)(C)C)cc4)nc2-3)cc1OC1CCCC1 CHEMBL360481 Ki 175.0 nM
COc1cccc(OCC(C)(C)c2nc3c(N)ncn(Cc4ccc(OC)c(OC5CCCC5)c4)c-3n2)c1 CHEMBL433761 Ki 175.0 nM
COc1ccc(Cn2cnc(N)c3nc(C(C)(C)O)nc2-3)cc1OC1CCCC1 CHEMBL1203921 Ki 179.0 nM
O=C(c1nn2c(c1-c1cccc(Cl)c1)OCCC2)N1CCC1 CHEMBL4174686 IC50 188.0 nM
COc1ccc(-c2ccc(-c3ccc4ccccc4n3)o2)cc1OC1CCCC1 CHEMBL326981 IC50 190.0 nM
CN1C(=O)c2c(nn(Cc3ccc(-c4ncccc4F)cc3)c2Nc2ccccc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3769932 Ki 200.0 nM
CC[C@H]1OC(=O)[C@H](C)[C@@H](OC(=O)CN2CCOCC2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C(=O)CN(C)C)[C@H]2O)[C@](C)(OC)C[C@@H](C)C(=O)[C@H](C)C2N(CCCOc3cc(C(=O)Nc4c(Cl)cncc4Cl)ccc3OC)C(=O)O[C@@]21C CHEMBL3650149 IC50 200.0 nM
NC(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911434 IC50 201.0 nM
COc1ccc(Cn2cnc(N)c3nc(C(C)(C)COc4ccc(C)cc4)nc2-3)cc1OC1CCCC1 CHEMBL360770 Ki 206.0 nM
COc1ccc(Cn2cnc(N)c3nc(C(C)(C)COc4cccc(F)c4)nc2-3)cc1OC1CCCC1 CHEMBL361201 Ki 208.0 nM
O=C(Nc1c(F)cccc1F)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O CHEMBL1911429 IC50 219.0 nM
O=c1c2cccnc2c(-c2cccc([N+](=O)[O-])c2)nn1Cc1ccncc1 CHEMBL315815 EC50 220.0 nM
CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2Oc2ccc(F)cc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3770977 Ki 220.0 nM
CCc1nnc2c3ccccc3nc(Nc3cccc(C(=O)O)c3)n12 CHEMBL5288859 IC50 220.0 nM
COc1ccc(Cn2cnc(N)c3nc(C(C)(C)COc4cccc(-c5ccsc5)c4)nc2-3)cc1OC1CCCC1 CHEMBL179321 Ki 223.0 nM
N#CCCc1ccc(OCc2cc(-c3cccc(F)c3)c3ncccc3c2)cc1 CHEMBL1223620 IC50 224.0 nM
COc1cc(OC)cc(OCC(C)(C)c2nc3c(N)ncn(Cc4ccc(OC)c(OC5CCCC5)c4)c-3n2)c1 CHEMBL178712 Ki 225.0 nM
CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C(=O)N3CCOCC3)[C@H]2O)[C@](C)(OC)CCC[C@@H](C)C(=O)[C@H](C)[C@H]2N(CCCN(Cc3c(Cl)cncc3Cl)c3ccc(OC)c(OC4CCCC4)c3)C(=O)O[C@]12C CHEMBL4110913 IC50 230.0 nM
CCNc1nc(Cl)nc(NC2(C#N)CCCCC2)n1 CHEMBL2402538 IC50 232.0 nM
COc1ccc(Cn2cnc(N)c3nc(C(C)(C)COc4ccccc4-c4cccs4)nc2-3)cc1OC1CCCC1 CHEMBL433757 Ki 236.0 nM
CN1C(=O)c2c(nn(Cc3ccc(-c4ccccn4)cc3)c2Nc2ccccc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3769817 Ki 240.0 nM
Cc1cc(Cl)ccc1-c1c(C(=O)N2CCC2)nn2c1OCCC2 CHEMBL4168594 IC50 241.0 nM
COc1cccc(-c2nc([C@H]3CC[C@H](C(=O)O)CC3)cc3cccnc23)c1 CHEMBL2172372 IC50 242.0 nM
COc1ccc(Cn2cnc(N)c3nc(C(C)(C)COc4ccc(F)c(F)c4)nc2-3)cc1OC1CCCC1 CHEMBL369134 Ki 244.0 nM
CNc1nc(Cl)nc(NC(C)(C)C)n1 CHEMBL1501511 IC50 245.0 nM
COc1cc2c(-c3cc(OCC4CC4)cc(OCC4CC4)c3)nc(OCCCO)nc2cc1OCCO CHEMBL96039 IC50 250.0 nM
O=c1c2c(ncn2Cc2cc(I)cc(C3(C(F)(F)F)N=N3)c2)c2cccnc2n1-c1ccccc1 CHEMBL340379 IC50 250.0 nM
CCc1nn(C2CCCC2)c2c1CCn1c(-c3cccnc3)nnc1-2 CHEMBL218990 IC50 250.0 nM
O=C(O)c1ccc(-c2cc3cccnc3c(-c3ccc4nonc4c3)n2)cc1 CHEMBL77826 EC50 250.0 nM
CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2Oc2ccccc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3769419 Ki 250.0 nM
COc1ccc(C(Cc2ccncc2)c2ccccc2OC)cc1OC1CCCC1 CHEMBL35390 IC50 259.0 nM
COc1ccc(C(=O)Cc2ccncc2)n2nc(C3(CO)CC3)nc12 CHEMBL3676251 IC50 261.0 nM
O=C1c2c(O)cccc2Cc2cccc(O)c21 CHEMBL46469 AC50 261.9 nM
O=c1c2cccnc2c(-c2cccc(Cl)c2)nn1CC1CC1 CHEMBL2158057 EC50 270.0 nM
COc1ccc(Cn2cnc(N)c3nc(C(C)(C)COc4ccccc4F)nc2-3)cc1OC1CCCC1 CHEMBL178460 Ki 271.0 nM
N#Cc1cccc(-c2nc(N3CCC(C(=O)O)CC3)cc3cccnc23)c1 CHEMBL2172370 IC50 271.0 nM
O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)cc1)c1cn(Cc2c(F)cccc2Cl)c2ccc(=O)[nH]c2c1=O CHEMBL1911582 IC50 274.0 nM
C=CCc1cc2cccnc2c(-c2cccc([N+](=O)[O-])c2)n1 CHEMBL351500 IC50 279.0 nM
COc1ccc(CCNC(=O)c2cnc(SC)nc2N2CCOCC2)cc1OC CHEMBL4283606 IC50 284.0 nM
COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)n2nc(CO)nc12 CHEMBL3676235 IC50 305.0 nM
N#CCCc1ccc(OCc2cc(-c3ccccc3)c3ncccc3c2)cc1 CHEMBL1223618 IC50 307.0 nM
COc1ccc(Cn2cnc(N)c3nc(C(C)(C)COc4ccc(C(F)(F)F)cc4)nc2-3)cc1OC1CCCC1 CHEMBL368739 Ki 309.0 nM
C[C@@H](Oc1ccc(CNC(=O)c2cccnc2Oc2ccc3c(c2)OCO3)c(F)c1)C(=O)O CHEMBL3182164 IC50 310.0 nM
COc1cccc(-c2cc(COc3cccc(Cl)c3)cc3cccnc23)c1 CHEMBL1224719 IC50 319.0 nM
CCC1C(C)=NN=C(c2ccc(OC)c(OC)c2)c2cc(OC)c(OC)cc21 CHEMBL404216 AC50 319.1 nM
CN1C(=O)c2c(nn(Cc3ccc(-c4cc(F)ccn4)cc3)c2Nc2ccccc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3769961 Ki 330.0 nM
COc1cccc(-c2cc(COc3ccc(C(F)(F)F)cc3)cc3cccnc23)c1 CHEMBL1224720 IC50 338.0 nM
O=C(c1ccccc1)c1cc(-c2ccccc2)oc1-c1ccccc1 CHEMBL109280 IC50 340.0 nM
O=[N+]([O-])c1cccc(-c2nc(-c3ccccc3)cc3cccnc23)c1 CHEMBL161465 IC50 350.0 nM
N#CCCc1ccc(OCc2cc(-c3cccc(OC(F)(F)F)c3)c3ncccc3c2)cc1 CHEMBL1223619 IC50 350.0 nM
CC(=O)Nc1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911424 IC50 362.0 nM
CC(=O)Nc1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911574 IC50 362.0 nM
O=C(O)C1CCN(c2cc3cccnc3c(-c3cccc(Cl)c3)n2)CC1 CHEMBL2172369 IC50 364.0 nM
COc1ccc(-c2ccc(-c3cccnc3)o2)cc1OC1CCCC1 CHEMBL111699 IC50 370.0 nM
CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2Nc2ccncc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3770947 Ki 370.0 nM
O=C(O)C1CCN(c2cc3cccnc3c(-c3cccc(OC(F)(F)F)c3)n2)CC1 CHEMBL2172367 IC50 371.0 nM
COc1cc2c(cc1OC)-c1cc(OCc3ccccc3F)nc(=O)n1CC2 CHEMBL4799579 IC50 372.0 nM
O=C(Nc1ccc(N2CCOCC2)cc1)c1cn(Cc2c(F)cccc2F)c2cccnc2c1=O CHEMBL1911416 IC50 379.0 nM
NS(=O)(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911581 IC50 385.0 nM
COc1ccc(C(Cc2ccc(C(=O)O)cc2)c2ccccc2)cc1OC1CCCC1 CHEMBL416041 IC50 389.0 nM
CN1C(=O)C2=C(Nc3ccccc3)NN(Cc3cccc(F)n3)C2N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3770721 Ki 390.0 nM
CN(C)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911573 IC50 402.0 nM
COc1ccc(OCC(C)(C)c2nc3c(N)ncn(Cc4ccc(OC)c(OC5CCCC5)c4)c-3n2)cc1OC CHEMBL178099 Ki 405.0 nM
COc1ccc(Cn2cnc(N)c3nc(C(C)(C)COc4ccc(OC(F)(F)F)cc4)nc2-3)cc1OC1CCCC1 CHEMBL360932 Ki 415.0 nM
CN1C(=O)c2c(nn(Cc3ccc(C(F)(F)F)cc3)c2Nc2ccc(F)cc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3769617 Ki 420.0 nM
COc1ccc(C(Cc2ccc(N)cc2)c2ccccc2)cc1OC1CCCC1 CHEMBL36006 Ki 423.0 nM
O=C(NCc1ccncc1)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911436 IC50 430.0 nM
CCN(CC)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911420 IC50 442.0 nM
NS(=O)(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911439 IC50 458.0 nM
Cn1cc(-c2ccncc2)c(-c2ccc(OCc3cc(CCCF)c4ccccc4n3)cc2)n1 CHEMBL3628715 IC50 460.0 nM
CN1C(=O)c2c(nn(Cc3ccc(-c4ccc(F)cc4)cc3)c2Nc2ccccc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3770427 Ki 460.0 nM
CCOc1ccc(Cc2nccc3cc(OCC)c(OCC)cc23)cc1OCC CHEMBL1555736 AC50 465.9 nM
CN(C)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911421 IC50 471.0 nM
Nc1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911423 IC50 477.0 nM
O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)cc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O CHEMBL1911440 IC50 481.0 nM
COc1cc2c(-c3cc(OCC4CC4)cc(OCC4CC4)c3)nc(NCCCO)nc2cc1OCCO CHEMBL97785 IC50 500.0 nM
COc1ccc([C@H]2CC(=O)N(C)C2)cc1OC1CCCC1 CHEMBL2158061 EC50 500.0 nM
CN1C(=O)c2c(nn(Cc3ccc(-c4ccc(F)cn4)cc3)c2Nc2ccccc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3769620 Ki 500.0 nM
O=C(Nc1ccc(N2CCOCC2)cc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O CHEMBL1911418 IC50 506.0 nM
COc1cc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc(OC)c1OC CHEMBL1911553 IC50 516.0 nM
CCCCOc1ccc(CC(=O)NO)cc1 CHEMBL94394 AC50 529.8 nM
COc1cccc(-c2nc(N3CCC(C(=O)O)CC3)cc3cccnc23)c1 CHEMBL2172366 IC50 537.0 nM
CCSc1nc(-c2cc(OCC3CC3)cc(OCC3CC3)c2)c2cc(OC)c(OCCO)cc2n1 CHEMBL99101 IC50 540.0 nM
COc1ccc(C(=O)Cc2nccnc2Cl)n2nc(C3(CO)CC3)nc12 CHEMBL3676255 IC50 548.0 nM
O=C1NC2=N[C@@H]3CCC[C@@H]3N2c2nn(Cc3ccc(C(F)(F)F)cc3)c(Nc3ccccc3)c21 CHEMBL3770641 Ki 550.0 nM
COc1cc2c(cc1OC)-c1cc(NCc3ccccc3)nc(=O)n1CC2 CHEMBL1871173 IC50 553.0 nM
COc1ccc(-c2ccc(-c3ccc(OC)c(OC)c3)o2)cc1OC CHEMBL110937 IC50 560.0 nM
CNC(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911435 IC50 560.0 nM
CN(c1nc(N)nc(Cl)n1)C1(C#N)CCCCC1 CHEMBL2402516 IC50 563.0 nM
O=C(Nc1ccc(OC(F)F)cc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O CHEMBL1911444 IC50 568.0 nM
NC(=O)c1cccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)c1 CHEMBL1911577 IC50 580.0 nM
COc1cc2c(cc1OC)-c1cc(OCCOc3ccccn3)nc(=O)n1CC2 CHEMBL4776061 IC50 586.0 nM
O=C(O)C1CCN(c2cc3cccnc3c(-c3cccc(F)c3)n2)CC1 CHEMBL2172368 IC50 587.0 nM
CSc1cccc(-c2nc(N3CCC(C(=O)O)CC3)cc3cccnc23)c1 CHEMBL2172371 IC50 587.0 nM
COc1ccc(-c2oc(-c3ccccn3)cc2C(=O)c2ccccc2)cc1OC1CCCC1 CHEMBL325846 IC50 590.0 nM
CCc1nc(-c2cc(OCC3CC3)cc(OCC3CC3)c2)c2ccc(OCCO)cc2n1 CHEMBL318444 IC50 630.0 nM
CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C(=O)N3CCOCC3)[C@H]2O)[C@](C)(OC)C[C@@H](C)C(=O)[C@H](C)[C@H]2N(CCCOc3cc(C(=O)Nc4c(Cl)cncc4Cl)ccc3OC)C(=O)O[C@]12C CHEMBL3650148 IC50 630.0 nM
CN(C)c1nc(Cl)nc(NC2(C#N)CCCCC2)n1 CHEMBL2402515 IC50 668.0 nM
CN1C(=O)C2=C(Nc3ccccc3)NN(Cc3ccc(C(F)(F)F)nc3)C2N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3770914 Ki 700.0 nM
COc1ccc([C@@H]2CC(=O)N(Cc3ccccc3)C2)cc1OC1CCCC1 CHEMBL2158064 IC50 730.0 nM
COc1ccc(-c2cc(S(=O)(=O)c3ccccc3)c(-c3ccccn3)o2)cc1OC1CCCC1 CHEMBL321864 IC50 740.0 nM
CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2N(C)c2ccccc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3769495 Ki 740.0 nM
COc1ccc(-c2oc(-c3ccccn3)cc2S(=O)(=O)c2ccccc2)cc1OC1CCCC1 CHEMBL324542 IC50 770.0 nM
N#Cc1cccc(-c2nc(OS(=O)(=O)C(F)(F)F)cc3cccnc23)c1 CHEMBL158286 IC50 770.0 nM
CCc1nn(C2CCCC2)c2c1CCn1c(-c3cccc(OC)c3)nnc1-2 CHEMBL218793 IC50 770.0 nM
CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2Cc2ccccc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3769484 Ki 770.0 nM
Clc1ccc(C(Cc2ccncc2)c2ccc3c(c2)OCCO3)cc1 CHEMBL284091 IC50 772.0 nM
CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2Cc2ccc(F)cc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3771078 Ki 780.0 nM
Cc1cccc(-c2cc(COc3ccc(CCC#N)cc3)cc3cccnc23)c1 CHEMBL1223684 IC50 819.0 nM
CC(=O)c1ccc(CCN2NC(Nc3ccccc3)=C3C(=O)N(C)C4=N[C@@H]5CCC[C@@H]5N4C32)cc1 CHEMBL3770286 Ki 860.0 nM
CC[C@H]1OC(=O)[C@H](C)[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C(=O)N3CCOCC3)[C@H]2O)[C@](C)(OC)CCC[C@@H](C)C(=O)[C@H](C)C2N(CCCN(Cc3c(Cl)cncc3Cl)c3ccc(OC)c(OC4CCCC4)c3)C(=O)O[C@@]21C CHEMBL3650147 IC50 880.0 nM
COc1cc2nc(C)nc(-c3cc(OCC4CC4)cc(OCC4CC4)c3)c2cc1OC CHEMBL96034 IC50 900.0 nM
Nc1nc2c([nH]1)c(=O)n(CC1CC1)c(=O)n2CC1CC1 CHEMBL356323 EC50 910.0 nM
CN1C(=O)c2c(nn(Cc3ccc(C(F)(F)F)cc3)c2Nc2ccccc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3769461 Ki 930.0 nM
CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2Sc2ccccc2)N2C1=N[C@@H]1CCC[C@@H]12 CHEMBL3769754 Ki 930.0 nM
CS(=O)(=O)c1cc(F)cc2c3c(n(Cc4ccc(Cl)cc4)c12)[C@@H](CC(=O)O)CC3 CHEMBL426559 AC50 960.0 nM
COc1cc(NC(=O)c2cn(Cc3c(Cl)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc(OC)c1OC CHEMBL1911570 IC50 979.0 nM
CNc1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911422 IC50 994.0 nM
COc1cc(-c2cccnc2)cc2c1nc(C)c1c(C)nc(-c3cccnc3)n12 CHEMBL3742354 IC50 1000.0 nM