CCOc1cc([C@H](Cc2c(Cl)c[n+]([O-])cc2Cl)OC(=O)c2ccc(CN[C@@](CO)(C(=O)O[C@H]3CN4CCC3CC4)c3ccccc3)s2)ccc1OC CHEMBL5417689 pIC50 0.02512 nM
CC(C)(C#N)c1cc(-c2cccc(CN(C(=O)Nc3ccccc3)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 CHEMBL380321 IC50 0.05 nM
Cc1ccc(/C(=C/c2cccc(-c3cc(C(C)C)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)nc1 CHEMBL197392 IC50 0.4 nM
CC(C)c1cc(-c2cccc(/C=C(/c3ccc(C(C)(C)O)cc3)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 CHEMBL198674 IC50 0.5 nM
CC(C)c1cc(-c2cccc(/C=C(\c3ccc(S(C)(=O)=O)cc3)c3nccs3)c2)c2ncccc2c1 CHEMBL196969 IC50 0.7 nM
Cc1cc(C(=O)N(Cc2cccc(-c3cc(C(C)(C)C#N)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)no1 CHEMBL206968 IC50 0.9 nM
[O-][n+]1cccc(C[C@@H](c2ccc(OC(F)F)c(OC3CC3)c2)c2cnc(C(O)(C(F)(F)F)C(F)(F)F)s2)c1 CHEMBL199015 IC50 1.0 nM
CC(C)(C#N)c1cc(-c2cccc(CN(C(=O)c3ccccc3)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 CHEMBL383225 IC50 1.0 nM
Cc1noc(/C(=C/c2cccc(-c3cc(C(C)C)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)n1 CHEMBL381681 IC50 1.2 nM
O=C(O)c1ccc(-c2cc3cccnc3c(-c3ccc4nonc4c3)n2)cc1 CHEMBL77826 IC50 1.23 nM
CC(C)NC(=O)N(Cc1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 CHEMBL377709 IC50 1.7 nM
CC(C)NC(=O)N(Cc1cccc(-c2cc(C(C)(C)C#N)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 CHEMBL382168 IC50 1.7 nM
O=C(Nc1c(Cl)cncc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1 CHEMBL193240 IC50 1.7 nM
CC(C)OCCOc1ncc(Oc2ccc3c(c2)B(O)OC3)cc1C#N CHEMBL5193314 IC50 2.1 nM
CC(C)NC(=O)/C(=C/c1cccc(-c2cc(C(C)C)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 CHEMBL371089 IC50 2.9 nM
COc1ccc(-c2ccc3c(c2)COC3=O)n2nc(C3(C(=O)OCC(C)C)CC3)nc12 CHEMBL4747201 IC50 3.0 nM
CCOc1cc([C@H](CS(C)(=O)=O)N2C(=O)c3cccc(NC(=O)OCCOCCOCCOC)c3C2=O)ccc1OC CHEMBL4759270 IC50 3.0 nM
CCOc1cc([C@H](CS(C)(=O)=O)N2C(=O)c3cccc(NC(=O)OCCOCCOCCOCCOCCOCCOCCOC)c3C2=O)ccc1OC CHEMBL4757093 IC50 3.0 nM
CCOc1cc([C@H](CS(C)(=O)=O)N2C(=O)c3cccc(NC(=O)OCCOCCOCCOCCOCCOCCOCCOCCOC)c3C2=O)ccc1OC CHEMBL4787980 IC50 3.0 nM
CCOc1cc([C@H](CS(C)(=O)=O)N2C(=O)c3cccc(NC(=O)OCCOCCOCCOCCOCCOCCOC)c3C2=O)ccc1OC CHEMBL4750999 IC50 3.0 nM
CCOc1cc([C@H](CS(C)(=O)=O)N2C(=O)c3cccc(NC(=O)OCCOCCOCCOCCOCCOC)c3C2=O)ccc1OC CHEMBL4752341 IC50 3.0 nM
CCOc1cc([C@H](CS(C)(=O)=O)N2C(=O)c3cccc(NC(=O)OCCOCCOCCOCCOC)c3C2=O)ccc1OC CHEMBL4784887 IC50 3.0 nM
COc1cccc(-c2cc(Cc3ccncc3)cc3cccnc23)c1 CHEMBL198432 IC50 3.3 nM
COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)cc1OC1CCCC1 CHEMBL42126 IC50 3.8 nM
CC(C)c1cc(-c2cccc(/C=C(/C(=O)O)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 CHEMBL197386 IC50 3.8 nM
CC(C)OC(=O)N(Cc1cccc(-c2cc(C(C)(C)C#N)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 CHEMBL209295 IC50 4.2 nM
COc1ccc([C@H](Cc2ccncc2)c2ccccc2)cc1OC1CCCC1 CHEMBL32442 IC50 4.5 nM
O=C(NC1CC1)c1nc2cccnn2c1-c1cc(F)c(Cl)c(F)c1 CHEMBL5283294 IC50 4.69 nM
CC(C)(c1cc(-c2cccc(C(=O)Nc3c(Cl)cncc3Cl)c2)c2ncccc2c1)S(C)(=O)=O CHEMBL207996 IC50 5.5 nM
Cc1noc(/C(=C/c2cccc(-c3cc(C(C)C)cc4cccnc34)c2)c2ccccn2)n1 CHEMBL197494 IC50 5.7 nM
CC(c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)N(C(=O)c1ccc(C(C)(C)O)cc1)c1ccc(S(C)(=O)=O)cc1 CHEMBL380933 IC50 5.9 nM
CC(C)NC(=O)N(Cc1cc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)ccc1F)c1ccc(S(C)(=O)=O)cc1 CHEMBL208100 IC50 6.4 nM
CC(C)NC(=O)/C(=C/c1cccc(-c2cc(C(C)(C)C#N)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 CHEMBL371037 IC50 6.8 nM
CC(c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)N(C(=O)c1ccc(F)cc1)c1ccc(S(C)(=O)=O)cc1 CHEMBL208382 IC50 7.5 nM
Cc1noc(/C(=C/c2cccc(-c3cc(C(C)(C)S(C)(=O)=O)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)n1 CHEMBL372575 IC50 9.1 nM
CC(C)(C#N)c1cc(-c2cccc(CN(Cc3ccc(F)cc3)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 CHEMBL378681 IC50 9.5 nM
COc1ccc(C2=NN(C3CCCCCC3)C(=O)C2(C)C)cc1OCCCCOc1ccc(-c2nn[nH]n2)cc1 CHEMBL2171452 IC50 10.0 nM
CC(C)(c1cc(-c2cccc(NC(=O)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1)S(C)(=O)=O CHEMBL208236 IC50 10.6 nM
CC(c1cc(-c2cccc(/C=C(\c3ccc(S(C)(=O)=O)cc3)c3ncc(C(C)(C)O)s3)c2)c2ncccc2c1)S(C)(=O)=O CHEMBL198722 IC50 11.0 nM
CC(C)NC(=O)/C(=C\c1cccc(-c2cc(C(C)(C)C#N)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 CHEMBL198853 IC50 11.4 nM
O=S(=O)(Nc1cccc(-c2cc(Cc3ccncc3)cc3cccnc23)c1)c1ccccc1 CHEMBL370220 IC50 11.9 nM
CC(C)NC(=O)/C(=C/c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 CHEMBL198527 IC50 14.0 nM
Cc1noc(/C(=C\c2cccc(-c3cc(C(C)(C)S(C)(=O)=O)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)n1 CHEMBL198732 IC50 14.0 nM
CC(c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)N(C(=O)c1cccnc1)c1ccc(S(C)(=O)=O)cc1 CHEMBL206592 IC50 14.0 nM
COc1ccc(C(=O)NCC(=O)NO)cc1OC1CCCC1 CHEMBL91571 IC50 15.3 nM
CC(c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)N(C(=O)C1CC1)c1ccc(S(C)(=O)=O)cc1 CHEMBL379768 IC50 17.0 nM
CC(C)(c1cc(-c2cccc(C(=O)Nc3ccncc3)c2)c2ncccc2c1)S(C)(=O)=O CHEMBL383837 IC50 17.0 nM
COc1ccc(C2=NOC(C(=O)NO)C2)cc1OC1CCCC1 CHEMBL307646 IC50 18.0 nM
CC(C)c1cc(-c2cccc(C(Cc3ccncc3)c3ccc(Cl)cc3)c2)c2ncccc2c1 CHEMBL382545 IC50 22.0 nM
CC(C)NC(=O)N(c1ccc(S(C)(=O)=O)cc1)C(C)c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1 CHEMBL207559 IC50 25.0 nM
CC(C)(c1cc(-c2cccc(C(=O)Nc3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1)S(C)(=O)=O CHEMBL208149 IC50 26.0 nM
COC(=O)Cc1ccc(OCc2cc(-c3cccc(OC)c3)c3ncccc3c2)cc1 CHEMBL1224717 IC50 31.2 nM
O=C(NC1CC1)c1nn2c(c1-c1cc(F)c(Cl)cc1F)OC[C@@H](F)C2 CHEMBL4168265 IC50 31.4 nM
O=C(O)Cc1ccc(OCc2cc(-c3cccc(OC(F)F)c3)c3ncccc3c2)cc1 CHEMBL1223687 IC50 32.2 nM
CS(=O)(=O)c1ccc(OCc2cc(-c3cccc(OC(F)F)c3)c3ncccc3c2)cc1 CHEMBL1223686 IC50 36.2 nM
COc1ccc(-c2nc(C(F)(F)F)ncc2C(=O)Nc2c(Cl)cncc2Cl)cc1OC CHEMBL4278921 IC50 39.0 nM
CCc1nn(C2CCCC2)c2c1CCn1c-2nnc1C(C)(C)C CHEMBL218103 IC50 40.0 nM
CC(=O)N(c1ccc(S(C)(=O)=O)cc1)C(C)c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1 CHEMBL204522 IC50 41.0 nM
COc1ccc(OC)c(-c2nnc3n2N=C(c2ccc(OC)c(O[C@@H]4CCOC4)c2)CS3)c1 CHEMBL564209 IC50 46.0 nM
O=C(c1nn2c(c1-c1cccc(Cl)c1)OCCC2)N1CCC1 CHEMBL4174686 IC50 48.2 nM
N#Cc1ccc(Oc2ccc3c(c2)COB3O)cc1 CHEMBL484785 IC50 55.0 nM
COc1ccc(-c2nc(C(F)(F)F)ncc2C(=O)Nc2ccncc2)cc1OC CHEMBL4282274 IC50 57.0 nM
O=C(O)c1ccc(-c2cc3cccnc3c(-c3cccc([N+](=O)[O-])c3)n2)cc1 CHEMBL74078 IC50 68.0 nM
CC(C)c1cc(-c2cccc(C(Cc3cc[n+]([O-])cc3)c3ccc(Cl)cc3)c2)c2ncccc2c1 CHEMBL198464 IC50 68.0 nM
COc1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1 CHEMBL1224653 IC50 69.5 nM
CC(C)NC(=O)N(Cc1cc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)ccc1Cl)c1ccc(S(C)(=O)=O)cc1 CHEMBL207424 IC50 70.0 nM
CCc1nn(C2CCCC2)c2c1CCn1c(-c3ccccc3Cl)nnc1-2 CHEMBL218653 IC50 77.0 nM
COc1ccc(NC(=O)c2cnc(SC)nc2N2CCOCC2)cc1OC CHEMBL4284354 IC50 77.0 nM
COc1ccc(C2=NOC(C)(C(=O)NO)C2)cc1OC1CCCC1 CHEMBL91551 IC50 95.2 nM
CC(C)(c1cc(-c2cccc(C(=O)Nc3ccccc3)c2)c2ncccc2c1)S(C)(=O)=O CHEMBL207775 IC50 97.0 nM
COc1cccc(-c2cc(COc3cccc(Cl)c3)cc3cccnc23)c1 CHEMBL1224719 IC50 102.1 nM
N#CCCc1ccc(OCc2cc(-c3cccc(OC(F)F)c3)c3ncccc3c2)cc1 CHEMBL1223685 IC50 103.0 nM
O=C(c1nn2c(c1-c1cc(F)c(Cl)cc1F)OCCC2)N1CCC1 CHEMBL4168448 IC50 104.0 nM
CC(C)c1cc(-c2cccc(CC(c3ccncc3)C(C)(C)O)c2)c2ncccc2c1 CHEMBL198564 IC50 106.0 nM
COc1ccc(OC)c(-c2nnc3ccc(-c4ccc(OC)c(O[C@@H]5CCOC5)c4)nn23)c1 CHEMBL549560 IC50 106.0 nM
Cc1cc(C#N)c(F)cc1-c1c(C(=O)NC2CC2)nn2c1OCC(F)C2 CHEMBL4176593 IC50 108.0 nM
COc1ccc(C2CNC(=O)C2)cc1OC1CCCC1 CHEMBL63 IC50 118.0 nM
COc1ccc(C(=O)NC(C)C(=O)NO)cc1OC1CCCC1 CHEMBL90375 IC50 125.9 nM
[O-][n+]1cccc(C[C@H](c2ccc(OC(F)F)c(OC3CC3)c2)c2cnc(C(O)(C(F)(F)F)C(F)(F)F)s2)c1 CHEMBL383762 IC50 135.0 nM
CC(C)(O)CCc1ccc(OCc2cc(-c3cccc(OC(F)F)c3)c3ncccc3c2)cc1 CHEMBL1221434 IC50 151.0 nM
COc1ccc(NC(=O)c2cnc(C(F)(F)F)nc2N2CCOCC2)cc1OC CHEMBL4295242 IC50 156.0 nM
Cc1cc(Cl)ccc1-c1c(C(=O)NC2CC2)nn2c1OCC(F)C2 CHEMBL4164367 IC50 160.0 nM
O=C(O)c1ccc(-c2cc3cccnc3c(-c3cccc(Cl)c3)n2)cc1 CHEMBL161115 IC50 190.0 nM
COc1ccc(/C=N/N(C)C(=O)c2ccc(O)cc2)cc1OC CHEMBL2172710 IC50 206.0 nM
COc1cccc(-c2cc(COc3ccc(C(F)(F)F)cc3)cc3cccnc23)c1 CHEMBL1224720 IC50 218.0 nM
CC(C)C(=O)c1c(C(C)C)nn2ccccc12 CHEMBL19449 IC50 239.0 nM
O=C(Nc1cccnc1)c1ccc(OC(F)F)c(OCC2CC2)c1 CHEMBL3884224 IC50 269.0 nM
O=C(Nc1cccnc1)c1ccc(OC(F)F)c(OC2CCCC2)c1 CHEMBL3885161 IC50 294.0 nM
COc1ccc(CCNC(=O)c2cnc(SC)nc2N2CCOCC2)cc1OC CHEMBL4283606 IC50 326.0 nM
O=C(NC1CC1)c1nn2c(c1-c1ccnc(OC(F)F)c1)OCCC2 CHEMBL4163945 IC50 389.0 nM
O=C(Nc1ccccc1Cl)c1ccc(OC(F)F)c(OC2CCCC2)c1 CHEMBL3883753 IC50 400.0 nM
COc1cccc(-c2cc(COc3ccc(CCC#N)cc3)cc3cccnc23)c1 CHEMBL1224721 IC50 414.0 nM
COc1ccc(OC)c(-c2nnc3n2N=C(c2ccc(OC)c(OC)c2)CS3)c1 CHEMBL252387 IC50 452.0 nM
COc1cccc(-c2cc(COc3ccccc3Cl)cc3cccnc23)c1 CHEMBL1224718 IC50 469.0 nM
CC(C)(c1cc(-c2cccc(C(N)=O)c2)c2ncccc2c1)S(C)(=O)=O CHEMBL210840 IC50 490.0 nM
O=C(Nc1ccccc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1 CHEMBL3884788 IC50 501.0 nM
COc1ccc(C(=O)N(C)/N=C/c2ccc(OC)c(OC)c2)cc1 CHEMBL2172734 IC50 505.0 nM
N#Cc1cccc(-c2nc(-c3ccc(C(=O)O)cc3)cc3cccnc23)c1 CHEMBL161740 IC50 570.0 nM
COc1cc(-c2cccc3nc(-c4cccs4)oc23)cc(OC)c1OC CHEMBL4853923 IC50 570.0 nM
O=[N+]([O-])c1cccc(-c2nc(-c3cccnc3)cc3cccnc23)c1 CHEMBL351613 IC50 610.0 nM
COc1ccc([C@]2(C#N)CC[C@@H](C(=O)O)CC2)cc1OC1CCCC1 CHEMBL511115 IC50 610.0 nM
Cc1cc(Cl)ccc1-c1c(C(=O)N2CCC2)nn2c1OCCC2 CHEMBL4168594 IC50 653.0 nM
CCc1nn(C2CCCC2)c2c1CCn1c(-c3cccnc3)nnc1-2 CHEMBL218990 IC50 700.0 nM
C=CCc1cc2cccnc2c(-c2cccc([N+](=O)[O-])c2)n1 CHEMBL351500 IC50 890.0 nM