O=C(OC[C@H](C1CCNCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 CHEMBL3286930 Kd 0.077 nM
CNc1nccc(CN(CC2CCNCC2)S(=O)(=O)c2ccc(S(=O)(=O)N(Cc3ccc(Cl)cc3)C3CCCC3)cc2)n1 CHEMBL4472979 Kd 0.203 nM
Cc1ccc(-n2nc3c(=O)n(CCC(=O)N4CCC(N5C(=O)c6ccccc6NC5c5ccccc5F)CC4)nc(C)c3c2C)cc1 CHEMBL4061005 Kd 0.6 nM
c1ccc(Cn2c(-c3ccc(OC[C@H](C4CCNCC4)n4c(-c5ccccc5)nc5ccccc54)cc3)nc3ccccc32)cc1 CHEMBL3286929 Kd 1.1 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCC(C)c4ccccc4)nc(C)c3c2C)cc1 CHEMBL1387422 Kd 2.2 nM
O=C1c2ccccc2N[C@@H](c2ccccc2F)N1CCN1CCC(N2C(=O)c3ccccc3N[C@H]2c2ccccc2F)CC1 CHEMBL4090695 Kd 2.3 nM
O=C1c2ccccc2NC(c2ccccc2F)N1CCCCCCN1C(=O)c2ccccc2NC1c1ccccc1F CHEMBL4061982 Kd 4.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCN4CCC(N5C(=O)c6ccccc6NC5c5ccccc5F)CC4)nc(C)c3c2C)cc1 CHEMBL4082888 Kd 4.0 nM
O=C1c2cc(F)ccc2NC(c2ccccc2F)N1CCOc1ccc(-c2nc3ccccc3n2Cc2ccncc2)cc1 CHEMBL4073926 Kd 4.5 nM
Cc1nc2ccccc2n1CCOC(=O)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 CHEMBL3286915 Kd 6.0 nM
O=C(OC[C@H](C1CCNCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1 CHEMBL3286909 Kd 7.0 nM
O=C(OCCn1ccnc1-c1ccccc1)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 CHEMBL3286914 Kd 7.0 nM
c1ccc(Cn2c(-c3ccc(OCCn4ccnc4-c4ccccc4)cc3)nc3ccccc32)cc1 CHEMBL3286917 Kd 7.0 nM
CC(C)c1nc2ccccc2n1[C@H](COC(=O)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1)C1CCNCC1 CHEMBL3286910 Kd 8.0 nM
O=C1c2ccccc2NC(c2ccccc2F)N1CCCCCN1C(=O)c2ccccc2NC1c1ccccc1F CHEMBL4090022 Kd 8.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCCCCCCCNc4ccc5c(c4)C(=O)N(C4CCC(=O)NC4=O)C5=O)nc(C)c3c2C)cc1 CHEMBL4635027 Kd 8.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCc4ccc(NC(=O)CCCC(=O)NCC56CC7CC(CC(C7)C5)C6)cc4)nc(C)c3c2C)cc1 CHEMBL5092661 Ki 8.6 nM
O=C(OCC(C1CCNCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1 CHEMBL3286902 Kd 9.0 nM
CCc1nc2ccccc2n1[C@H](COC(=O)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1)C1CCNCC1 CHEMBL3286912 Kd 9.0 nM
O=C1c2ccccc2NC(c2ccccc2F)N1CCCCCCCN1C(=O)c2ccccc2NC1c1ccccc1F CHEMBL4091313 Kd 9.0 nM
O=C1c2ccccc2NC(c2ccccc2F)N1CCOc1ccc(-c2nc3ccccc3n2Cc2ccncc2)cc1 CHEMBL4100698 Kd 9.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCCCCCCCNc4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)nc(C)c3c2C)cc1 CHEMBL4647310 Kd 9.0 nM
Cc1ccc2c(c1)C(=O)N(CCOc1ccc(-c3nc4ccccc4n3Cc3ccncc3)cc1)C(c1ccccc1F)N2 CHEMBL4099759 Kd 9.3 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCC45CC6CC(CC(C6)C4)C5)nc(C)c3c2C)cc1 CHEMBL5084153 Ki 9.3 nM
CC1=NN(CCCC(=O)NCC(C)c2ccccc2)Cc2nn(-c3ccc(C)cc3)c(C)c21 CHEMBL5426895 Kd 9.3 nM
COc1ccc2c(c1)NC(c1ccccc1F)N(CCOc1ccc(-c3nc4ccccc4n3Cc3ccncc3)cc1)C2=O CHEMBL4077104 Kd 9.8 nM
O=C(OCC(C1CCNCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 CHEMBL3286897 Kd 10.0 nM
O=C(OCC(C1CCCNC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 CHEMBL3286904 Kd 11.0 nM
O=C1c2cc(Cl)ccc2NC(c2ccccc2F)N1CCOc1ccc(-c2nc3ccccc3n2Cc2ccncc2)cc1 CHEMBL4102432 Kd 11.6 nM
O=C(OC[C@H](C1CCNCC1)n1c(C2CC2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1 CHEMBL3286911 Kd 12.0 nM
O=C1c2ccccc2NC(c2ccccc2F)N1CCN1CCC(N2C(=O)c3ccccc3NC2c2ccccc2F)CC1 CHEMBL4092911 Kd 12.0 nM
O=C1c2ccc(F)cc2NC(c2ccccc2F)N1CCOc1ccc(-c2nc3ccccc3n2Cc2ccncc2)cc1 CHEMBL4087332 Kd 12.1 nM
O=C(OCC(C1CCNC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 CHEMBL3286905 Kd 13.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NC45CC6CC(CC(C6)C4)C5)nc(C)c3c2C)cc1 CHEMBL5089219 Ki 13.6 nM
O=C(OCC(CC1CCNCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 CHEMBL3286906 Kd 14.0 nM
O=C(OCCn1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 CHEMBL3286916 Kd 14.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCCCCCCNc4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)nc(C)c3c2C)cc1 CHEMBL4641483 Kd 14.0 nM
O=C1c2ccccc2NC(c2ccccc2F)N1CC1CCC(CN2C(=O)c3ccccc3NC2c2ccccc2F)CC1 CHEMBL4069561 Kd 15.0 nM
c1ccc(Cn2c(-c3ccc(OCC(C4CCCCC4)n4c(-c5ccccc5)nc5ccccc54)cc3)nc3ccccc32)cc1 CHEMBL3286886 Kd 16.0 nM
O=C(OCC(C1CCCCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1 CHEMBL3286903 Kd 16.0 nM
CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(=O)N1CCOCC1 CHEMBL3286923 Kd 16.0 nM
O=C1c2ccccc2NC(c2ccccc2F)N1CCOc1ccc(N2C(=O)c3ccccc3NC2c2ccccc2F)cc1 CHEMBL4072582 Kd 16.0 nM
O=C1c2ccc(Cl)cc2NC(c2ccccc2F)N1CCOc1ccc(-c2nc3ccccc3n2Cc2ccncc2)cc1 CHEMBL4105186 Kd 16.0 nM
CC(C)C(COC(=O)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1)n1c(-c2ccccc2)nc2ccccc21 CHEMBL3286899 Kd 17.0 nM
Cc1nc2ccccc2n1CCOc1ccc(-c2nc3ccccc3n2Cc2ccccc2)cc1 CHEMBL3286918 Kd 17.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCCCCCNc4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)nc(C)c3c2C)cc1 CHEMBL4646627 Kd 17.0 nM
CC(C)C(COc1ccc(-c2nc3ccccc3n2Cc2ccccc2)cc1)n1c(-c2ccccc2)nc2ccccc21 CHEMBL3286885 Kd 20.0 nM
CC(C)Cc1nnc(SCc2ccc(C(=O)Nc3ccc(N(C)C)cc3)cc2)n1Cc1ccccc1 CHEMBL4440294 IC50 21.0 nM
O=C1c2ccccc2NC(c2ccccc2F)N1CCN1CCC(CN2C(=O)c3ccccc3NC2c2ccccc2F)CC1 CHEMBL4060010 Kd 22.0 nM
O=C1c2ccccc2NC(c2ccccn2)N1c1ccc(OCCn2ccnc2-c2ccccc2)cc1 CHEMBL4075625 Kd 22.0 nM
COc1ccc(CSc2nnc(-c3ccc(OCC(=O)NC4CCCCC4)cc3)n2Cc2ccccc2)cc1 CHEMBL4459864 IC50 24.0 nM
O=C(OCC(C1CCCCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 CHEMBL3286898 Kd 25.0 nM
COc1ccc(CSc2nnc(-c3ccc(OCC(=O)Nc4cccnc4)cc3)n2Cc2ccccc2)cc1 CHEMBL4527667 IC50 25.0 nM
COc1ccc(CCc2nnc(-c3ccc(OC(C)C(=O)Nc4cnn(C)c4)cc3)n2Cc2ccccc2)cc1 CHEMBL4555739 IC50 25.2 nM
CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(=O)NCCCOCCOCCOCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21 CHEMBL3286925 Kd 26.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCCCCCNC(=O)CC45CC6CC(CC(C6)C4)C5)nc(C)c3c2C)cc1 CHEMBL5094121 Ki 26.0 nM
CCC(Oc1ccc(-c2nnc(CCc3ccc(OC)cc3)n2Cc2ccccc2)cc1)C(=O)Nc1cnn(C)c1 CHEMBL4532027 IC50 26.4 nM
CC(C)Cc1nnc(SCc2ccc(C(=O)Nc3ccc(F)cc3)cc2)n1Cc1ccccc1 CHEMBL4548659 IC50 27.0 nM
COc1ccc(CSc2nnc(-c3ccc(OCC(=O)Nc4cnn(C)c4)cc3)n2Cc2ccccc2)cc1 CHEMBL4514611 IC50 27.3 nM
O=C1c2ccccc2NC(c2ccccc2F)N1c1ccc(OCCn2ccnc2-c2ccccc2)cc1 CHEMBL4077358 Kd 29.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCCCCNc4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)nc(C)c3c2C)cc1 CHEMBL4649810 Kd 29.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCCCCCCCNC(=O)CC45CC6CC(CC(C6)C4)C5)nc(C)c3c2C)cc1 CHEMBL5077941 Ki 29.0 nM
CC(C)Cc1nnc(SCc2ccc(C(=O)NC3CCCCC3)cc2)n1Cc1ccccc1 CHEMBL4536719 IC50 30.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCCCNc4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)nc(C)c3c2C)cc1 CHEMBL4648416 Kd 30.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCCCCCCCNc4cccc5c4C(=O)N(C4CCC(=O)N(C)C4=O)C5=O)nc(C)c3c2C)cc1 CHEMBL4644891 Kd 30.0 nM
O=C1c2ccccc2N[C@H](c2ccccc2F)N1CCN1CCC(N2C(=O)c3ccccc3N[C@H]2c2ccccc2F)CC1 CHEMBL4080394 Kd 33.0 nM
CC(C)Cc1nnc(SCc2ccc(C(=O)Nc3ccccc3F)cc2)n1Cc1ccccc1 CHEMBL4440110 IC50 33.0 nM
COc1ccc(CCc2nnc(-c3ccc(OC(C)(C)C(=O)Nc4cnn(C)c4)cc3)n2Cc2ccccc2)cc1 CHEMBL4589625 IC50 33.6 nM
O=C(OCC(C1CCNCC1)n1c(-c2ccccc2)nc2ccccc21)N1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 CHEMBL3286908 Kd 35.0 nM
Cc1nc2ccccc2n1[C@H](COC(=O)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1)C1CCNCC1 CHEMBL3286913 Kd 35.0 nM
CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(=O)NCCN(C)C CHEMBL3286922 Kd 35.0 nM
CC(C)Cc1nnc(SCc2ccc(C(=O)Nc3ccccc3)cc2)n1Cc1ccccc1 CHEMBL4588289 IC50 35.0 nM
COCCOCCOCCCNC(=O)C[C@H](O)C[C@H](O)CCn1c(-c2ccc(F)cc2)c(-c2ccccc2)c(C(=O)Nc2ccccc2)c1C(C)C CHEMBL3286924 Kd 36.0 nM
CN1c2ccc(F)cc2C(=O)N(C2CCN(CCCn3ccnc3-c3ccccc3)CC2)C1c1ccccc1F CHEMBL4080396 Kd 37.0 nM
CC(C)Cc1nnc(SCc2ccc(C(=O)Nc3cccc(F)c3)cc2)n1Cc1ccccc1 CHEMBL4566147 IC50 37.0 nM
O=C1c2cc(F)ccc2N(CC2CC2)C(c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 CHEMBL4076391 Kd 38.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCNC(=O)CC45CC6CC(CC(C6)C4)C5)nc(C)c3c2C)cc1 CHEMBL5086138 Ki 38.8 nM
C=CCC(COc1ccc(-c2nc3ccccc3n2Cc2ccccc2)cc1)n1c(-c2ccccc2)nc2ccccc21 CHEMBL3286884 Kd 39.0 nM
CC(C)Cc1nnc(SCc2ccc(C(=O)Nc3ccc(-c4ccccc4)cc3)cc2)n1Cc1ccccc1 CHEMBL4585643 IC50 39.0 nM
COc1ccc(CSc2nnc(-c3ccc(OCC(=O)Nc4cc(C)nn4C)cc3)n2Cc2ccccc2)cc1 CHEMBL4443518 IC50 40.3 nM
COc1ccc(CCc2nnc(-c3ccc(OCC(=O)Nc4cnn(C)c4)cc3)n2Cc2ccccc2)cc1 CHEMBL4449262 IC50 40.9 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCCC(=O)NCC45CC6CC(CC(C6)C4)C5)nc(C)c3c2C)cc1 CHEMBL5079726 Ki 41.0 nM
COc1ccc(CSc2nnc(-c3ccc(OCC(=O)Nc4ccc(N(C)C)cc4)cc3)n2Cc2ccccc2)cc1 CHEMBL4439169 IC50 41.1 nM
COc1ccc(NC(=O)c2ccc(CSc3nnc(CC(C)C)n3Cc3ccccc3)cc2)cc1 CHEMBL4443194 IC50 43.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCCCCC(=O)NCC45CC6CC(CC(C6)C4)C5)nc(C)c3c2C)cc1 CHEMBL5083136 Ki 44.4 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCc4ccc(NC(=O)CCCCCC(=O)NCC56CC7CC(CC(C7)C5)C6)cc4)nc(C)c3c2C)cc1 CHEMBL5087129 Ki 45.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCCCNC(=O)CC45CC6CC(CC(C6)C4)C5)nc(C)c3c2C)cc1 CHEMBL5072868 Ki 49.3 nM
O=C1c2cc(F)ccc2N(CC2CCC2)C(c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 CHEMBL4088248 Kd 50.0 nM
CNc1cc(CN(CC2CCNCC2)S(=O)(=O)c2ccc(S(=O)(=O)N(Cc3ccc(Cl)cc3)C3CCCC3)cc2)ccc1C(=O)NCCOCCOCC(=O)NCCCN(C(=O)c1ccc(C)cc1)[C@@H](c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1)C(C)C CHEMBL5415524 Kd 51.0 nM
CNc1cc(CN(CC2CCNCC2)S(=O)(=O)c2ccc(S(=O)(=O)N(Cc3ccc(Cl)cc3)C3CCCC3)cc2)ccc1C(=O)NCCCCCCNC(=O)COc1c(Br)cc(/C=C2\C(=O)Nc3ccc(I)cc32)cc1Br CHEMBL5403101 Kd 52.0 nM
Cc1nccn1CCOc1ccc(N2C(=O)c3ccccc3NC2c2ccccc2F)cc1 CHEMBL4078030 Kd 53.0 nM
Cc1ccc2c(c1)C(=O)N(C1CCN(CCCn3ccnc3-c3ccccc3)CC1)C(c1ccccc1F)N2 CHEMBL4090598 Kd 56.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCCCCCNC(=O)COc4c(Br)cc(/C=C5\C(=O)Nc6ccc(I)cc65)cc4Br)nc(C)c3c2C)cc1 CHEMBL5439010 Kd 56.0 nM
CNc1cc(CN(CC2CCNCC2)S(=O)(=O)c2ccc(S(=O)(=O)N(Cc3ccc(Cl)cc3)C3CCCC3)cc2)ccc1C(=O)NCCOCCOCCNC(=O)COc1c(Br)cc(/C=C2\C(=O)Nc3ccc(I)cc32)cc1Br CHEMBL5411442 Kd 57.0 nM
O=C1c2ccccc2N[C@@H](c2ccccc2F)N1CCN1CCC(N2C(=O)c3ccccc3N[C@@H]2c2ccccc2F)CC1 CHEMBL4073704 Kd 57.8 nM
O=C1c2cc(F)ccc2N(CC2CCCC2)C(c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 CHEMBL4089186 Kd 60.0 nM
CC(C)Cc1nnc(SCc2ccc(C(=O)Nc3cccc(C(F)(F)F)c3)cc2)n1Cc1ccccc1 CHEMBL4590921 IC50 61.0 nM
CC(C)Cc1nnc(SCc2ccc(C(=O)Nc3ccc(C(F)(F)F)cc3)cc2)n1Cc1ccccc1 CHEMBL4538447 IC50 64.0 nM
O=C1c2ccccc2NC(c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 CHEMBL4076573 Kd 67.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCCOCCOCCOCCCNc4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)nc(C)c3c2C)cc1 CHEMBL4635450 Kd 70.0 nM
CNc1cc(CN(CC2CCNCC2)S(=O)(=O)c2ccc(S(=O)(=O)N(Cc3ccc(Cl)cc3)C3CCCC3)cc2)ccc1C(=O)NCCCCCC(=O)NCCCN(C(=O)c1ccc(C)cc1)[C@@H](c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1)C(C)C CHEMBL5419692 Kd 71.0 nM
CNc1cc(CN(CC2CCNCC2)S(=O)(=O)c2ccc(S(=O)(=O)N(Cc3ccc(Cl)cc3)C3CCCC3)cc2)ccc1C(=O)NCCCC(=O)NCCCN(C(=O)c1ccc(C)cc1)[C@@H](c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1)C(C)C CHEMBL5420032 Kd 73.0 nM
CNc1cc(CN(CC2CCNCC2)S(=O)(=O)c2ccc(S(=O)(=O)N(Cc3ccc(Cl)cc3)C3CCCC3)cc2)ccc1C(=O)NCCCCNC(=O)COc1c(Br)cc(/C=C2\C(=O)Nc3ccc(I)cc32)cc1Br CHEMBL5406378 Kd 74.0 nM
Cc1ccc(C(=O)N(CCCNC(=O)COCCOCCNC(=O)CCCn2nc(C)c3c(C)n(-c4ccc(C)cc4)nc3c2=O)[C@@H](c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)C(C)C)cc1 CHEMBL5422170 Kd 74.0 nM
O=C1c2ccccc2NC(c2ccccc2F)N1CCCCN1C(=O)c2ccccc2NC1c1ccccc1F CHEMBL4084687 Kd 76.0 nM
O=C(OCC(C1CCNCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2c(F)cccc2Cl)CC1 CHEMBL3286900 Kd 77.0 nM
O=C1c2ccccc2NC(c2ccccc2F)N1c1ccc(OCCn2ccnc2)cc1 CHEMBL4105255 Kd 80.0 nM
O=C1c2cc(F)ccc2N(CC2CCCCC2)C(c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 CHEMBL4061011 Kd 81.0 nM
C=CC(=O)Oc1ccc(-c2nc3ccccc3n2Cc2ccccc2)cc1 CHEMBL3286919 Kd 82.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCCCCCCCNC(=O)COc4c(Br)cc(/C=C5\C(=O)Nc6ccc(I)cc65)cc4Br)nc(C)c3c2C)cc1 CHEMBL5413531 Kd 82.0 nM
Cc1ccc(C(=O)N(CCCNC(=O)CCCNC(=O)CCCn2nc(C)c3c(C)n(-c4ccc(C)cc4)nc3c2=O)[C@@H](c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)C(C)C)cc1 CHEMBL5428558 Kd 82.0 nM
O=C1c2cc(F)ccc2NC(c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 CHEMBL4104621 Kd 85.0 nM
c1ccc(Cn2c(-c3ccc(OCC(C4CCNCC4)n4c(-c5ccccc5)nc5ccccc54)cc3)nc3ccccc32)cc1 CHEMBL3286892 Kd 87.0 nM
Cc1ccc(C(=O)N(CCCNC(=O)CCCCCNC(=O)CCCn2nc(C)c3c(C)n(-c4ccc(C)cc4)nc3c2=O)[C@@H](c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)C(C)C)cc1 CHEMBL5408872 Kd 94.0 nM
O=C1c2ccc(F)cc2NC(c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 CHEMBL4097634 Kd 101.0 nM
Cc1ccc2c(c1)NC(c1ccccc1F)N(C1CCN(CCCn3ccnc3-c3ccccc3)CC1)C2=O CHEMBL4072274 Kd 105.0 nM
C=CC(=O)N1CCC([C@@H](COc2ccc(-c3nc4ccccc4n3Cc3ccccc3)cc2)n2c(-c3ccccc3)nc3ccccc32)CC1 CHEMBL3286921 Kd 108.0 nM
CC(C)Cc1nnc(SCc2ccc(C(=O)Nc3ccc4ncccc4c3)cc2)n1Cc1ccccc1 CHEMBL4450839 IC50 113.0 nM
O=C(OCC(C1CCCCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2c(F)cccc2Cl)CC1 CHEMBL3286901 Kd 115.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCOCCOCCNC(=O)COc4c(Br)cc(/C=C5\C(=O)Nc6ccc(I)cc65)cc4Br)nc(C)c3c2C)cc1 CHEMBL5431289 Kd 116.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCOCCOCCNC(=O)CC45CC6CC(CC(C6)C4)C5)nc(C)c3c2C)cc1 CHEMBL5084808 Ki 132.0 nM
CCc1nnc(SCc2ccc(C(=O)Nc3ccc(F)cc3)cc2)n1Cc1ccccc1 CHEMBL4541410 IC50 137.0 nM
COc1ccc2c(c1)C(=O)N(C1CCN(CCCn3ccnc3-c3ccccc3)CC1)C(c1ccccc1F)N2 CHEMBL4075474 Kd 146.0 nM
Cc1nc2ccccc2n1CCOc1ccc(N2C(=O)c3ccccc3NC2c2ccccc2F)cc1 CHEMBL4095012 Kd 146.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCc4ccc(NC(=O)CCCCCCNC(=O)CC56CC7CC(CC(C7)C5)C6)cc4)nc(C)c3c2C)cc1 CHEMBL5082602 Ki 146.5 nM
CNc1cc(CN(CC2CCNCC2)S(=O)(=O)c2ccc(S(=O)(=O)N(Cc3ccc(Cl)cc3)C3CCCC3)cc2)ccc1C(=O)NCCCCCCCCNC(=O)COc1c(Br)cc(/C=C2\C(=O)Nc3ccc(I)cc32)cc1Br CHEMBL5425110 Kd 153.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCOCCOCCNc4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)nc(C)c3c2C)cc1 CHEMBL4642256 Kd 160.0 nM
c1ccc(Cn2c(-c3ccc(OCC(CC4CCNCC4)n4c(-c5ccccc5)nc5ccccc54)cc3)nc3ccccc32)cc1 CHEMBL3286891 Kd 162.0 nM
c1ccc(Cn2c(-c3ccccc3)nc3ccccc32)cc1 CHEMBL1922082 Kd 165.0 nM
Cc1nccn1CCOc1ccc(N2C(=O)c3ccccc3NC2c2ccccn2)cc1 CHEMBL4075823 Kd 166.0 nM
COc1ccc2c(c1)NC(c1ccccc1F)N(C1CCN(CCCn3ccnc3-c3ccccc3)CC1)C2=O CHEMBL4070463 Kd 167.0 nM
O=C1c2ccccc2NC(c2ccccc2F)N1c1ccc(OCCn2c(-c3ccccc3)nc3ccccc32)cc1 CHEMBL4078490 Kd 168.0 nM
O=C1c2ccccc2NC(c2ccccn2)N1c1ccc(OCCn2ccnc2)cc1 CHEMBL4076983 Kd 170.0 nM
Cc1cccc(Cn2c(-c3ccc(OCC(C4CCNCC4)n4c(-c5ccccc5)nc5ccccc54)cc3)nc3ccccc32)c1 CHEMBL3286895 Kd 191.0 nM
O=C1c2ccccc2NC(c2ccccn2)N1c1ccc(OCCn2c(-c3ccccc3)nc3ccccc32)cc1 CHEMBL4067589 Kd 192.0 nM
c1ccc(Cn2c(-c3ccc(OCC(C4CCCNC4)n4c(-c5ccccc5)nc5ccccc54)cc3)nc3ccccc32)cc1 CHEMBL3286890 Kd 207.0 nM
Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NCCCNc4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)nc(C)c3c2C)cc1 CHEMBL4636954 Kd 216.0 nM
O=C1c2cccc3cccc(c23)N1c1ccc(-c2ccccc2)cc1 CHEMBL4083592 Kd 227.0 nM
c1ccc(-c2nc3ccccc3n2C(COc2ccc(-c3nc4ccccc4n3Cc3cccnc3)cc2)C2CCNCC2)cc1 CHEMBL3286893 Kd 231.0 nM
Fc1ccc(Cn2c(-c3ccc(OCC(C4CCNCC4)n4c(-c5ccccc5)nc5ccccc54)cc3)nc3ccccc32)cc1 CHEMBL3286894 Kd 251.0 nM
Cc1nccn1CCCn1c(-c2ccccc2)cc(-c2nc3ccccc3n2CC2CC2)c1C(C)C CHEMBL3286926 Kd 251.0 nM
O=C(CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)NCCCOCCOCCOCCCNC(=O)CC(COc1ccc(-c2nc3ccccc3n2Cc2ccccc2)cc1)n1c(-c2ccccc2)nc2ccccc21 CHEMBL3286888 Kd 328.0 nM
Cc1nccn1CCCn1c(-c2ccccc2)cc(-c2nc3ccccc3n2CC2CCCC2)c1C(C)C CHEMBL3286927 Kd 347.0 nM
Cc1ccccc1Cn1c(-c2ccc(OCC(C3CCNCC3)n3c(-c4ccccc4)nc4ccccc43)cc2)nc2ccccc21 CHEMBL3286896 Kd 474.0 nM
Cc1nnc(SCc2ccc(C(=O)Nc3ccc(F)cc3)cc2)n1Cc1ccccc1 CHEMBL4565589 IC50 540.0 nM
Cc1nccn1CCCn1c(-c2ccccc2)cc(-c2nc3ccccc3n2Cc2ccccc2)c1C(C)C CHEMBL3286928 Kd 689.0 nM
O=C(NCC(C1CCNCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1 CHEMBL3286907 Kd 720.0 nM
O=C(O)CC(COc1ccc(-c2nc3ccccc3n2Cc2ccccc2)cc1)n1c(-c2ccccc2)nc2ccccc21 CHEMBL3286887 Kd 870.0 nM