CCn1c(Nc2ccncc2F)nc2c(C3CCCN(C(=O)C4(C#N)CC4)C3)csc2c1=O CHEMBL3360172 IC50 0.32 nM
CCn1c(Nc2ccncc2F)nc2c(C3CCCN(C(=O)OC)C3)csc2c1=O CHEMBL3360170 IC50 0.68 nM
CCn1c(NC2CCCC2)nc2c(-c3ccc(N4CCOCC4)nc3)csc2c1=O CHEMBL3354181 IC50 1.0 nM
CCn1c(Nc2ccncc2F)nc2c(C3CCN(C(=O)OC)CC3)csc2c1=O CHEMBL3360169 IC50 1.1 nM
CCn1c(Nc2ccncc2F)nc2c(C3CCCN(C(=O)C(C)(C)CO)C3)csc2c1=O CHEMBL3360171 IC50 1.2 nM
COc1cc(N)ccc1-c1nc2c(c(C3CCCCC3)nn2C)c(=O)[nH]1 CHEMBL2019020 IC50 1.3 nM
COc1cc(N)ccc1-c1cc2c(c(=O)[nH]1)C(C1CCCCC1)N=[N+]2C CHEMBL3924897 IC50 1.3 nM
CCn1c(NC(C)C)nc2c(C3CCN(C(=O)c4ncccc4C)C3)csc2c1=O CHEMBL3403373 IC50 1.4 nM
CCn1c(NC(C)C)nc2c(C3CCN(C(=O)c4ccccc4)C3)csc2c1=O CHEMBL3403371 IC50 1.5 nM
CCn1c(NC2CCCC2)nc2c(-c3cccnc3)csc2c1=O CHEMBL3354179 IC50 2.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCNC4=O)nc3)cc12 CHEMBL3650287 IC50 2.0 nM
CCn1c(Nc2ccncc2F)nc2c(C(C)(C)O)csc2c1=O CHEMBL3360167 IC50 2.1 nM
CCn1c(NC2CCCC2)nc2c(-c3ccc(CN4CCOCC4)cc3)csc2c1=O CHEMBL3354180 IC50 2.3 nM
CCn1c(NC(C)C)nc2c(C3CCN(C(=O)c4ccccn4)C3)csc2c1=O CHEMBL3403372 IC50 2.7 nM
COc1cc(C2CC2C(N)=O)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171440 IC50 3.0 nM
CNC1CCN([C@H]2CC[C@H](NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)CC2)CC1 CHEMBL3650254 IC50 3.1 nM
CCn1c(NC(C)C)nc2c(C3CCN(C(=O)c4cccc(C)n4)C3)csc2c1=O CHEMBL3403346 IC50 3.3 nM
O=C1Nc2c(Cl)ccc(OCc3noc(O)n3)c2C2(CCCCC2)N1 CHEMBL182536 IC50 3.5 nM
CC(=O)N1CCN([C@H]2CC[C@H](NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)CC2)CC1 CHEMBL3650259 IC50 3.5 nM
Cc1nc(N)c2ccc(-c3nn(C)/c(=N/C4CCCCC4)s3)cc2n1 CHEMBL186868 IC50 3.9 nM
CCn1c(Nc2ccncc2F)nc2c(CCCO)csc2c1=O CHEMBL3360168 IC50 3.9 nM
O=C1Nc2c(Cl)ccc(OCc3nn[nH]n3)c2C2(CCCCC2)N1 CHEMBL184861 IC50 4.0 nM
COc1cc(N2CCCNCC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019104 IC50 4.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4C(=O)CN(C)C4=O)CC3)cc12 CHEMBL3650301 IC50 4.0 nM
CCn1c(NC2CCCC2)nc2c(C#Cc3cccnc3)csc2c1=O CHEMBL3354171 IC50 4.2 nM
CCn1c(NC(C)C)nc2c(-c3cccnc3)csc2c1=O CHEMBL3403358 IC50 4.4 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCC(O)CC4)c(C#N)c3)cc12 CHEMBL3650322 IC50 4.5 nM
CCn1c(NC(C)C)nc2c(-c3ccnc(OC)c3)csc2c1=O CHEMBL3403361 IC50 4.6 nM
CCn1c(NC2CCCC2)nc2c(-c3ccc(C(=O)OC)cc3)csc2c1=O CHEMBL3354178 IC50 4.9 nM
CCn1c(NC2CCCC2)nc2c(-c3cccc(C(=O)OC)c3)csc2c1=O CHEMBL3354177 IC50 5.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCNC(=O)C4)cc3)cc12 CHEMBL3650313 IC50 5.0 nM
CCn1c(NC(C)C)nc2c(C3CCCN(C(C)=O)C3)csc2c1=O CHEMBL3403367 IC50 5.1 nM
CCn1c(NC2CCCC2)nc2c(-c3ccccc3)csc2c1=O CHEMBL3354175 IC50 5.6 nM
COc1cc(N)ccc1-c1nc2c(C)nn(C3CCCCC3)c2c(=O)[nH]1 CHEMBL3670399 IC50 5.67 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4C(=O)CN(C)C4=O)cc3)cc12 CHEMBL3650267 IC50 6.1 nM
CCn1c(NC(C)C)nc2c(-c3sc(C)nc3C)csc2c1=O CHEMBL3403360 IC50 6.4 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCNCC4)CC3)cc12 CHEMBL3650258 IC50 6.5 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CCC(CN4C(=O)CNC4=O)CC3)cc12 CHEMBL3950502 IC50 6.5 nM
COc1ccc(Cn2c(=O)c3cc(OC(F)F)ccc3n(C3CCN(C=O)CC3)c2=O)cc1OC CHEMBL3646898 IC50 6.7 nM
CCn1c(NC(C)C)nc2c(C3CCN(c4ccccn4)CC3)csc2c1=O CHEMBL3403365 IC50 6.8 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCC(N)CC4)CC3)cc12 CHEMBL3650257 IC50 6.8 nM
COc1cc(N2CCCC(O)CC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019109 IC50 7.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCC(O)CC4)c(C(=O)O)c3)cc12 CHEMBL3650323 IC50 7.2 nM
CCn1c(NC2CCCC2)nc2c(CCc3cccnc3)csc2c1=O CHEMBL3354173 IC50 7.3 nM
CCn1c(NC(C)C)nc2c(-c3cncnc3)csc2c1=O CHEMBL3403362 IC50 7.6 nM
CNC(=O)C1CCC(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)CC1 CHEMBL3937956 IC50 7.8 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CCC(C(=O)NC4CC4)CC3)cc12 CHEMBL3936324 IC50 7.8 nM
COc1cc(N2CCC(N)CC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019106 IC50 8.0 nM
Cc1nn(C2CCCCCC2)c2sc(C(=O)Nc3ccc(N4CCN(C)CC4)cc3)cc12 CHEMBL3647495 IC50 8.0 nM
CCn1c(NC(C)C)nc2c(C3CCN(C(=O)CC(C)C)C3)csc2c1=O CHEMBL3403370 IC50 8.1 nM
CCn1c(NC(C)C)nc2c(C3CCN(C(=O)C(C)C)C3)csc2c1=O CHEMBL3403369 IC50 8.4 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCC(N(C)C)CC4)CC3)cc12 CHEMBL3650256 IC50 8.6 nM
CCn1c(Nc2ccncc2F)nc2c(C(C)O)csc2c1=O CHEMBL3360166 IC50 8.7 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCC(O)CC4)nc3)cc12 CHEMBL3650319 IC50 8.7 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCCN(C)CC4)c(F)c3)cc12 CHEMBL3650260 IC50 8.9 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCNC4=O)CC3)cc12 CHEMBL3650298 IC50 8.9 nM
COc1cc(N2CCNCC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019103 IC50 9.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCN(C)CC4)cc3)cc12 CHEMBL3647491 IC50 9.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CCC(N4CCOCC4)CC3)cc12 CHEMBL3965715 IC50 9.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCCS4(=O)=O)CC3)cc12 CHEMBL3650300 IC50 9.9 nM
O=C1Nc2c(Cl)ccc(Cl)c2C2(CCCCC2)N1 CHEMBL427152 IC50 10.0 nM
O=C1Nc2c(Cl)cc(-c3ccccc3)cc2C2(CCCCC2)N1 CHEMBL182703 IC50 10.0 nM
O=C1Nc2c(Cl)cc(-c3ccc(C(=O)O)cc3)cc2C2(CCCCC2)N1 CHEMBL185304 IC50 10.0 nM
CN(C)CCCNC(=O)c1cccc(-c2cc(Cl)c3c(c2)C2(CCCCC2)NC(=O)N3)c1 CHEMBL182617 IC50 10.0 nM
CN1CCN(C(=O)c2ccc(-c3cc(Cl)c4c(c3)C3(CCCCC3)NC(=O)N4)cc2)CC1 CHEMBL183465 IC50 10.0 nM
COc1ccc(Cl)c2c1C1(CCCCC1)NC(=O)N2 CHEMBL185101 IC50 10.0 nM
O=C1Nc2c(Cl)ccc(O)c2C2(CCCCC2)N1 CHEMBL183102 IC50 10.0 nM
CCOC(=O)c1ccc(COc2ccc(Cl)c3c2C2(CCCCC2)NC(=O)N3)o1 CHEMBL359890 IC50 10.0 nM
O=C1Nc2c(Cl)ccc(OCc3ccc(C(=O)O)o3)c2C2(CCCCC2)N1 CHEMBL365447 IC50 10.0 nM
O=C1Nc2c(Cl)ccc(OCCCS(=O)(=O)O)c2C2(CCCCC2)N1 CHEMBL360627 IC50 10.0 nM
NC(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911576 IC50 10.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCNCC4)cc3)cc12 CHEMBL3647478 IC50 10.0 nM
CNS(=O)(=O)c1cccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)c1 CHEMBL3647494 IC50 10.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCN(C)CC4)c(F)c3)cc12 CHEMBL3650240 IC50 10.0 nM
CC(=O)N(C)C1CCN([C@H]2CC[C@H](NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)CC2)CC1 CHEMBL3650255 IC50 10.0 nM
COc1cc(N2CCC(O)CC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019108 IC50 11.0 nM
Cc1cc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)ccc1N1CCC(O)CC1 CHEMBL3650321 IC50 11.0 nM
CS(=O)(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911579 IC50 12.0 nM
COc1cc(N2CCCN(C(C)=O)CC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019113 IC50 12.0 nM
CCOc1cc(N2CCC(N)CC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019125 IC50 12.0 nM
COc1cc(N2CCCNCC2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171423 IC50 12.0 nM
CCn1c(NC2CCCC2)nc2c(N3CCN(C(=O)OC(C)(C)C)CC3=O)csc2c1=O CHEMBL3354182 IC50 12.0 nM
CCn1c(NC(C)C)nc2c(-c3ccco3)csc2c1=O CHEMBL3403359 IC50 12.0 nM
CC(=O)N1CCN(c2ccc(NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)cc2)CC1 CHEMBL3647479 IC50 12.0 nM
O=C(Nc1ccc(N2CCOCC2)cc1)c1cn(Cc2c(F)cccc2Cl)c2ccc(=O)[nH]c2c1=O CHEMBL1911559 IC50 13.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4C[C@@H](C)O[C@@H](C)C4)CC3)cc12 CHEMBL3650253 IC50 13.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CC[C@@H](C(=O)N(C)C)C3)cc12 CHEMBL3650277 IC50 13.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C(=O)NCCO)nc3)cc12 CHEMBL3650325 IC50 13.0 nM
COc1cc(N)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019021 IC50 14.0 nM
COc1cc(N)ccc1-c1nc2snc(-c3c(F)cccc3Cl)c2c(=O)[nH]1 CHEMBL2019134 IC50 14.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C(=O)N(C)C)cc3)cc12 CHEMBL3647465 IC50 14.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C4CCN(C)CC4)cc3)cc12 CHEMBL3647503 IC50 14.0 nM
CNC1CCN(c2ccc(NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)cc2F)CC1 CHEMBL3650244 IC50 14.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4C(=O)CCC4=O)CC3)cc12 CHEMBL3650299 IC50 14.0 nM
COc1ccc(-c2cc3c(n2-c2ccc(S(=O)(=O)Nc4nc(C)cc(C)n4)cc2)CCC(N2CCN(C)CC2)C3)cc1C CHEMBL4211493 IC50 14.0 nM
COc1cc(N2CCNC(=O)C2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019122 IC50 15.0 nM
CCn1c(NC(C)C)nc2c(C3CCN(C(C)=O)C3)csc2c1=O CHEMBL3403368 IC50 15.0 nM
COc1ccc(Cn2c(=O)c3cc(OCC(F)F)ccc3n(C3CCN(C=O)CC3)c2=O)cc1OC CHEMBL3646894 IC50 15.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCN(C)CC4)nc3)cc12 CHEMBL3647492 IC50 15.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCCN(C)CC4)CC3)cc12 CHEMBL3650247 IC50 15.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CCC(C(=O)N4CCC(O)CC4)CC3)cc12 CHEMBL3908383 IC50 15.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CC[C@H](CN4C(=O)CNC4=O)C3)cc12 CHEMBL3650289 IC50 15.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCOC4=O)CC3)cc12 CHEMBL3650297 IC50 15.0 nM
COc1c(OCC2CC2)cc2oc3cc4c(c(OCc5ccncc5)c3c(=O)c2c1CC=C(C)C)C=CC(C)(C)O4 CHEMBL5407967 IC50 15.0 nM
COc1cc(N2CCC(CO)CC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019110 IC50 16.0 nM
COc1cc(N2CCN(C(C)=O)CC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019112 IC50 16.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCN(C)CC4)CC3)cc12 CHEMBL3650246 IC50 16.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(CCN(C)C)cc3)cc12 CHEMBL3650264 IC50 16.0 nM
CC(=O)Nc1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911574 IC50 17.0 nM
CNC(=O)Nc1ccc(-c2nc3snc(C4CCCCC4)c3c(=O)[nH]2)c(OC)c1 CHEMBL2019123 IC50 17.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CCN(C(=O)N(C)C)CC3)cc12 CHEMBL3650278 IC50 17.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCN(C)C4=O)CC3)cc12 CHEMBL3639491 IC50 17.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCC(O)CC4)c(F)c3F)cc12 CHEMBL3650320 IC50 17.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCN(C)CC4=O)CC3)cc12 CHEMBL3650338 IC50 17.0 nM
COc1cc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc(OC)c1OC CHEMBL1911553 IC50 18.0 nM
CC(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911575 IC50 18.0 nM
CNC(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911578 IC50 18.0 nM
COc1cc(N2CC(O)C2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019107 IC50 18.0 nM
CNC(=O)C1CCN(c2ccc(-c3nc4snc(C5CCCCC5)c4c(=O)[nH]3)c(OC)c2)CC1 CHEMBL2019119 IC50 18.0 nM
COc1cc(N2CCNC(=O)C2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171435 IC50 18.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(CCN4CCOCC4)cc3)cc12 CHEMBL3650265 IC50 18.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CCC(C(=O)N(C)CCO)CC3)cc12 CHEMBL3893432 IC50 18.0 nM
COc1ccc(C2=NN(C3CCCC3)C(=O)C3CC=CCC23)cc1Cl CHEMBL4213295 IC50 18.0 nM
CCn1c(NC2CCCC2)nc2c(C#CCN3CCOCC3)csc2c1=O CHEMBL3354172 IC50 19.0 nM
CC(=O)N1CCc2cc(NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)ccc21 CHEMBL3647451 IC50 19.0 nM
CC(=O)N1CCN([C@H]2CC[C@H](NC(=O)c3cc4c(C)nn(C5CCOCC5)c4s3)CC2)CC1 CHEMBL3650330 IC50 19.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4C[C@@H](C)O[C@@H](C)C4)CC3)cc12 CHEMBL3650332 IC50 19.0 nM
O=C1Nc2c(Cl)cc(-c3cccc(C(=O)O)c3)cc2C2(CCCCC2)N1 CHEMBL427505 IC50 20.0 nM
NC(=O)c1ccc(-c2cc(Cl)c3c(c2)C2(CCCCC2)NC(=O)N3)cc1 CHEMBL185296 IC50 20.0 nM
CN(C)CCNC(=O)c1ccc(-c2cc(Cl)c3c(c2)C2(CCCCC2)NC(=O)N3)cc1 CHEMBL366149 IC50 20.0 nM
CN(C)CCNC(=O)c1cccc(-c2cc(Cl)c3c(c2)C2(CCCCC2)NC(=O)N3)c1 CHEMBL363084 IC50 20.0 nM
CN(C)CCCNC(=O)c1ccc(-c2cc(Cl)c3c(c2)C2(CCCCC2)NC(=O)N3)cc1 CHEMBL427513 IC50 20.0 nM
N#CCOc1ccc(Cl)c2c1C1(CCCCC1)NC(=O)N2 CHEMBL184279 IC50 20.0 nM
CCNS(=O)(=O)c1cc(-c2nn(C)/c(=N/C3CCCCC3)s2)ccc1Cl CHEMBL184829 IC50 20.0 nM
Cn1nc(-c2ccc3c(N)ncnc3c2)s/c1=N\C1CCCCC1 CHEMBL364813 IC50 20.0 nM
O=C(NCc1ccncc1)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911436 IC50 20.0 nM
NS(=O)(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911581 IC50 20.0 nM
CCn1c(NC(C)C)nc2c(C3CCN(C(C)=O)CC3)csc2c1=O CHEMBL3403366 IC50 20.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(OCC(=O)N4CCN(C)CC4)cc3)cc12 CHEMBL3647481 IC50 20.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(OCC(=O)N(C)C)cc3)cc12 CHEMBL3647482 IC50 20.0 nM
CNC1CCN(c2ccc(NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)cc2Cl)CC1 CHEMBL3650245 IC50 20.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCC(O)CC4)CC3)cc12 CHEMBL3650252 IC50 20.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CCC(C(=O)N4CCOCC4)CC3)cc12 CHEMBL3945235 IC50 20.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NCC(C)(C)CN3C(=O)CNC3=O)cc12 CHEMBL3650311 IC50 20.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCC(O)CC4)cc3)cc12 CHEMBL3647496 IC50 20.0 nM
O=C(Nc1ccc(N2CCOCC2)cc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O CHEMBL1911418 IC50 22.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C4CCNCC4)cc3)cc12 CHEMBL3647502 IC50 22.0 nM
COC1CCN([C@H]2CC[C@H](NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)CC2)CC1 CHEMBL3650248 IC50 22.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCCNCC4)CC3)cc12 CHEMBL3650249 IC50 22.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C(=O)NCCN(C)C)nc3)cc12 CHEMBL3650327 IC50 22.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCN(S(C)(=O)=O)CC4)CC3)cc12 CHEMBL3650331 IC50 22.0 nM
COc1cc(N2CC[C@H](N)C2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019105 IC50 23.0 nM
CNC(=O)COc1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1 CHEMBL3647476 IC50 23.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CC[C@H](C(=O)N(C)C)C3)cc12 CHEMBL3650276 IC50 23.0 nM
CC(=O)Nc1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911424 IC50 24.0 nM
CNC(=O)Nc1ccc(-c2nc3c(C)nn(C4CCCCC4)c(=O)c3[nH]2)c(OC)c1 CHEMBL2171436 IC50 24.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CCC(C(=O)N4CCN(C)CC4)CC3)cc12 CHEMBL3903460 IC50 24.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCOCC4)CC3)cc12 CHEMBL3650318 IC50 24.0 nM
O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)cc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O CHEMBL1911440 IC50 25.0 nM
COc1cc(-c2cn[nH]c2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019124 IC50 25.0 nM
CCn1c(Nc2ccncc2F)nc2c(C#N)csc2c1=O CHEMBL3360165 IC50 25.0 nM
CNC(=O)Cc1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1 CHEMBL3647477 IC50 25.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CCC(C(=O)N(C)C)CC3)cc12 CHEMBL3946660 IC50 25.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C(=O)N[C@H]4CC[C@H](O)CC4)nc3)cc12 CHEMBL3650328 IC50 25.0 nM
CS(=O)(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911438 IC50 27.0 nM
COc1cc(N2CCC(N)CC2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171422 IC50 27.0 nM
COc1cc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)ccc1NC(C)=O CHEMBL3647450 IC50 27.0 nM
COCCNC(=O)c1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1 CHEMBL3647463 IC50 28.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)Nc3ccc(N4CCNC4=O)nc3)cc12 CHEMBL3650291 IC50 28.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CC[C@@H](O)C4)cc3)cc12 CHEMBL3650292 IC50 28.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)Nc3ccc(N4CCNC(=O)C4)cc3)cc12 CHEMBL3650314 IC50 28.0 nM
CC(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911433 IC50 29.0 nM
CNC(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911435 IC50 29.0 nM
CC[C@H](CN1C(=O)CNC1=O)NC(=O)c1cc2c(C)nn(C3CCCCC3)c2s1 CHEMBL3650310 IC50 29.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCN(C)C(=O)C4)CC3)cc12 CHEMBL3650340 IC50 29.0 nM
O=C1Nc2c(Cl)cc(-c3ccccn3)cc2C2(CCCCC2)N1 CHEMBL361469 IC50 30.0 nM
O=C1Nc2c(Cl)cc(-c3ccncc3)cc2C2(CCCCC2)N1 CHEMBL185208 IC50 30.0 nM
O=C1Nc2c(Cl)ccc(OCCN3CCOCC3)c2C2(CCCCC2)N1 CHEMBL185523 IC50 30.0 nM
Cn1nc(-c2ccc(C(=O)NCCN3CCOCC3)cc2)s/c1=N\C1CCCCC1 CHEMBL184154 IC50 30.0 nM
COc1cc(N)ccc1-c1nc2snc(-c3c(F)cccc3F)c2c(=O)[nH]1 CHEMBL2019132 IC50 30.0 nM
C=Cc1csc2c(=O)n(CC)c(NC3CCCC3)nc12 CHEMBL3354168 IC50 30.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C(=O)NCCO)cc3)cc12 CHEMBL3647469 IC50 30.0 nM
COCC(=O)Nc1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1 CHEMBL3647488 IC50 30.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(CN4CCC(O)CC4)nc3)cc12 CHEMBL3650335 IC50 30.0 nM
CCN1CCN([C@H]2CC[C@H](NC(=O)c3cc4c(C)nn(C5CCOCC5)c4s3)CC2)CC1=O CHEMBL3650344 IC50 30.0 nM
COc1cc(N2CCCNCC2)ccc1-c1nc2onc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019135 IC50 31.0 nM
COc1cc(N)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171421 IC50 31.0 nM
O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)cc1)c1cn(Cc2c(F)cccc2Cl)c2ccc(=O)[nH]c2c1=O CHEMBL1911582 IC50 32.0 nM
COc1cc(N2CCCN(C(C)=O)CC2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171434 IC50 32.0 nM
CC(=O)Nc1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cn1 CHEMBL3647470 IC50 32.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NCCN3C(=O)CN(C)C3=O)cc12 CHEMBL3650302 IC50 32.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(CO)nc3)cc12 CHEMBL3650333 IC50 32.0 nM
COc1cc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc(OC)c1OC CHEMBL1911565 IC50 33.0 nM
COc1cc(N2CCCC(O)CC2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171433 IC50 33.0 nM
CNC(=O)c1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1 CHEMBL3647455 IC50 33.0 nM
CC(=O)c1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1 CHEMBL3647464 IC50 33.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(CN4C(=O)CN(C)C4=O)cc3)cc12 CHEMBL3650266 IC50 33.0 nM
NS(=O)(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911439 IC50 34.0 nM
COc1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1Cl CHEMBL1911583 IC50 34.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCOCC4)cc3)cc12 CHEMBL3647454 IC50 34.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H](C)CN3C(=O)CNC3=O)cc12 CHEMBL3650309 IC50 34.0 nM
CCOc1cc(O[C@@H]2CCNC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019111 IC50 35.0 nM
CNC(=O)[C@H]1C[C@@H]1c1ccc(-c2nc3snc(C4CCCCC4)c3c(=O)[nH]2)c(OC)c1 CHEMBL2019120 IC50 35.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCC(O)CC4)c(F)c3)cc12 CHEMBL3650242 IC50 35.0 nM
CC(=O)N1CCN(Cc2ccc(NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)cn2)CC1 CHEMBL3650336 IC50 35.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc4c(c3)CCN4C(=O)C3CC3)cc12 CHEMBL3647473 IC50 36.0 nM
N#Cc1cc(Cn2c(=O)c3cc(OC(CF)CF)ccc3n(C3CCN(C=O)CC3)c2=O)ccc1-c1ccccc1 CHEMBL3646900 IC50 37.0 nM
CC(=O)Nc1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1 CHEMBL3647487 IC50 37.0 nM
CC(=O)N1CCCN([C@H]2CC[C@H](NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)CC2)CC1 CHEMBL3650250 IC50 37.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)Nc3ccc(N4C(=O)CN(C)C4=O)cc3)cc12 CHEMBL3650290 IC50 37.0 nM
CNC(=O)[C@@H]1C[C@H]1c1ccc(-c2nc3snc(C4CCCCC4)c3c(=O)[nH]2)c(OC)c1 CHEMBL2019121 IC50 38.0 nM
CN(C)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911573 IC50 39.0 nM
COc1cc(N)ccc1-c1nc2snc(-c3ccccc3F)c2c(=O)[nH]1 CHEMBL2019128 IC50 39.0 nM
CCn1c(NC2CCCC2)nc2c(CCCN3CCOCC3)csc2c1=O CHEMBL3354174 IC50 39.0 nM
COc1ccc(Cn2c(=O)c3cc(OC(CF)CF)ccc3n(C3CCN(C=O)CC3)c2=O)cc1OC CHEMBL3646893 IC50 39.0 nM
CN1CCN(C(=O)c2cccc(-c3cc(Cl)c4c(c3)C3(CCCCC3)NC(=O)N4)c2)CC1 CHEMBL185370 IC50 40.0 nM
O=C(O)COc1ccc(Cl)c2c1C1(CCCCC1)NC(=O)N2 CHEMBL183280 IC50 40.0 nM
O=C(O)CNCCOc1ccc(Cl)c2c1C1(CCCCC1)NC(=O)N2 CHEMBL363658 IC50 40.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(S(=O)(=O)N4CCN(C)CC4)cc3)cc12 CHEMBL3647462 IC50 40.0 nM
COc1cc(NC(=O)c2cc3c(C)nn(C4CCCCCC4)c3s2)ccc1NC(C)=O CHEMBL3647497 IC50 40.0 nM
CCn1c(Nc2ccccc2Cl)nc2ccsc2c1=O CHEMBL3360161 IC50 41.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CCN(S(=O)(=O)N(C)C)CC3)cc12 CHEMBL3650283 IC50 41.0 nM
CCc1csc2c(=O)n(CC)c(NC3CCCC3)nc12 CHEMBL3354167 IC50 42.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(CN4CCOCC4)nc3)cc12 CHEMBL3650334 IC50 43.0 nM
NC(=O)c1cccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)c1 CHEMBL1911577 IC50 44.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc4c(c3)CC(=O)N4)cc12 CHEMBL3647459 IC50 44.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C(=O)N4CCC(O)CC4)nc3)cc12 CHEMBL3650324 IC50 44.0 nM
COc1cc(-c2cn[nH]c2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171429 IC50 45.0 nM
C#Cc1csc2c(=O)n(CC)c(NC3CCCC3)nc12 CHEMBL3354169 IC50 45.0 nM
COc1cc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)ccc1C(=O)NCCO CHEMBL3647506 IC50 45.0 nM
CCN(CC)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911420 IC50 46.0 nM
COc1cc(NCCN)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019102 IC50 46.0 nM
COc1cc(N)ccc1-c1nc2snc(-c3ccc(F)cc3F)c2c(=O)[nH]1 CHEMBL2019133 IC50 46.0 nM
CNc1nc(NC2(C#N)CCCCC2)nc(SC)n1 CHEMBL2402520 IC50 46.0 nM
COc1cc(Cn2c(=O)c3cc(OC(CF)CF)ccc3n(C3CCN(C=O)CC3)c2=O)ccc1OCC(=O)N1CCCCC1 CHEMBL3646899 IC50 46.0 nM
CNC(=O)/C=C/c1ccc(-c2nc3snc(C4CCCCC4)c3c(=O)[nH]2)c(OC)c1 CHEMBL2019118 IC50 47.0 nM
COCCN(C)[C@H]1CC[C@H](NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)CC1 CHEMBL3650251 IC50 48.0 nM
NC(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911434 IC50 49.0 nM
O=C1Nc2c(Cl)cc(-c3cccnc3)cc2C2(CCCCC2)N1 CHEMBL184945 IC50 50.0 nM
O=C1Nc2c(Cl)ccc(OCCO)c2C2(CCCCC2)N1 CHEMBL183965 IC50 50.0 nM
CCNC(=O)c1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1 CHEMBL3647460 IC50 50.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C(=O)O)cc3)cc12 CHEMBL3647467 IC50 50.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C(=O)NC(C)C)cc3)cc12 CHEMBL3647468 IC50 50.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3CC[C@H](O)CC3)cc12 CHEMBL3647480 IC50 50.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CCC(CO)CC3)cc12 CHEMBL3971108 IC50 50.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCC(C(=O)N(C)C)CC4)CC3)cc12 CHEMBL3650343 IC50 50.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NCCN3CCN(C)C(=O)C3=O)cc12 CHEMBL3650275 IC50 51.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CCN(C(=O)N(C)C)C3)cc12 CHEMBL3650284 IC50 51.0 nM
CCCOc1ccc(Cl)c2c1C1(CCCCC1)NC(=O)N2 CHEMBL3639692 IC50 51.8 nM
COc1cc(N2CC(O)C2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171430 IC50 53.0 nM
CCOC(=O)Nc1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1 CHEMBL3647452 IC50 53.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CCN(C4CCOCC4)CC3)cc12 CHEMBL3647501 IC50 53.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CC[C@@H](O)C4)c(F)c3)cc12 CHEMBL3650293 IC50 54.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@H]3C[C@@H]3CO)cc12 CHEMBL3650312 IC50 54.0 nM
COc1cc(O[C@@H]2CCNC2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171428 IC50 55.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(NC=O)cc3)cc12 CHEMBL3647472 IC50 55.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCN(C)CC4)c(Cl)c3)cc12 CHEMBL3650241 IC50 55.0 nM
CCc1nc2c(cnn2CC)c(NC2CCCCC2)c1C1=NOC2(C1)CC(C1N=NN=N1)C2 CHEMBL4745497 IC50 55.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(CN4CCOCC4)cc3)cc12 CHEMBL3650263 IC50 56.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CC[C@H](C(=O)O)C3)cc12 CHEMBL3650274 IC50 56.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C(=O)N4CCN(C)CC4)nc3)cc12 CHEMBL3650326 IC50 56.0 nM
CC(=O)N1CCN(CC2CCC(NC(=O)c3cc4c(C)nn(C5CCOCC5)c4s3)CC2)CC1 CHEMBL3969790 IC50 57.0 nM
CC(=O)Nc1ccc(NC(=O)c2cc3c(C)nn(C4CCCCCC4)c3s2)cc1 CHEMBL3647485 IC50 58.0 nM
CNC(=O)c1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cn1 CHEMBL3647490 IC50 58.0 nM
CS(=O)(=O)c1cccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)c1 CHEMBL1911580 IC50 59.0 nM
COc1c(O)cc(-c2nn(C)/c(=N/C3CCCCC3)s2)cc1O CHEMBL365659 IC50 60.0 nM
Cn1nc(-c2ccc(C(N)=O)cc2)s/c1=N\C1CCCCC1 CHEMBL185446 IC50 60.0 nM
CC(=O)Nc1ccc(-c2nn(C)/c(=N/C3CCCCC3)s2)cc1 CHEMBL363097 IC50 60.0 nM
Cn1nc(-c2ccc(Cl)c(S(N)(=O)=O)c2)s/c1=N\C1CCCCC1 CHEMBL186615 IC50 60.0 nM
O=C1Nc2c(Br)cccc2C2(CCCCC2)N1 CHEMBL185360 IC50 60.0 nM
O=C1Nc2c(Br)cccc2C2(CCCCCC2)N1 CHEMBL366319 IC50 60.0 nM
CN(C)CCNC(=O)c1ccc(-c2nn(C)/c(=N/C3CCCCC3)s2)cc1 CHEMBL187201 IC50 60.0 nM
CCN(CC)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911572 IC50 60.0 nM
CCn1c(Nc2ccncc2F)nc2ccsc2c1=O CHEMBL3360164 IC50 60.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(S(=O)(=O)N4CCN(CCO)CC4)cc3)cc12 CHEMBL3647483 IC50 60.0 nM
CC(=O)N[C@H]1CC[C@H](NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)CC1 CHEMBL3647484 IC50 60.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NCCN3CCN(C)C3=O)cc12 CHEMBL3650303 IC50 60.0 nM
CCn1c(Nc2ccccc2F)nc2ccsc2c1=O CHEMBL3360160 IC50 61.0 nM
COc1ccc(Cn2c(=O)c3c(Cl)cc(Cl)cc3n(C3CCN(C=O)CC3)c2=O)cc1OC CHEMBL3646897 IC50 61.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCNC(=O)C4)CC3)cc12 CHEMBL3650339 IC50 63.0 nM
CC(=O)n1ccc2cc(NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)ccc21 CHEMBL3647475 IC50 65.0 nM
COc1cc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)ccc1C(=O)N1CCC(O)CC1 CHEMBL3647505 IC50 65.0 nM
CN(C)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911421 IC50 66.0 nM
COc1cc(N2CCN(S(C)(=O)=O)CC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019114 IC50 66.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NCCN3C(=O)CNC3=O)cc12 CHEMBL3650304 IC50 66.0 nM
CCn1c(NC2CCCC2)nc2c(C#N)csc2c1=O CHEMBL3354170 IC50 67.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NCCN3CC(=O)N(C)C3=O)cc12 CHEMBL3650307 IC50 67.0 nM
COc1cc(-c2n[nH]c(=O)o2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171437 IC50 68.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CC[C@H](CO)C3)cc12 CHEMBL3650288 IC50 68.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCC(O)CC4)c(Cl)c3)cc12 CHEMBL3650243 IC50 70.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(S(=O)(=O)N4CCC(O)CC4)cc3)cc12 CHEMBL3650295 IC50 70.0 nM
O=C(Nc1ccc(OC(F)F)cc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O CHEMBL1911444 IC50 71.0 nM
COc1cc(N2CCC(O)C2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171431 IC50 71.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)N[C@@H]3CCN(C(=O)N(C)C)C3)cc12 CHEMBL3650308 IC50 71.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)NC3CCC(CN4CCOCC4)CC3)cc12 CHEMBL3943690 IC50 71.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCC(CO)CC4)CC3)cc12 CHEMBL3650341 IC50 72.0 nM
COc1cc(N2CC(N)C2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171427 IC50 73.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C(=O)N4CCCN(C)CC4)nc3)cc12 CHEMBL3650329 IC50 74.0 nM
COc1cc(N2CCC(N)CC2)ccc1-c1nc2c(C)nn(C3CCCCCC3)c(=O)c2[nH]1 CHEMBL2171442 IC50 75.0 nM
CCOC(=O)c1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1 CHEMBL3647466 IC50 75.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C(=O)NC(C)(C)C)cc3)cc12 CHEMBL3647471 IC50 75.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3cccc(S(=O)(=O)N4CCN(C)CC4)c3)cc12 CHEMBL3647493 IC50 75.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N(C)CCO)c(F)c3)cc12 CHEMBL3647498 IC50 75.0 nM
COc1cc(N2CC[C@@H](N)C2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171426 IC50 77.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CCC(C#N)CC3)cc12 CHEMBL3919691 IC50 77.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)NC3CCC(C(=O)N(C)C)CC3)cc12 CHEMBL3937029 IC50 78.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)Nc3ccc(N4CCN(C)CC4)c(F)c3)cc12 CHEMBL3650262 IC50 79.0 nM
Cn1nc(-c2ccc(Cl)cc2)s/c1=N\c1cccc(-c2nn[nH]n2)c1 CHEMBL185203 IC50 80.0 nM
Cn1nc(-c2ccc(C(N)=O)c(N)c2)s/c1=N\C1CCCCC1 CHEMBL363118 IC50 80.0 nM
COc1cc(N)ccc1-c1nc2snc(-c3ccccc3Cl)c2c(=O)[nH]1 CHEMBL2019131 IC50 80.0 nM
COc1cc(N2CC[C@H](N)C2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171425 IC50 80.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc4c(c3)CCN4S(C)(=O)=O)cc12 CHEMBL3647474 IC50 80.0 nM
COc1cc(N2CCC(O)CC2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171432 IC50 81.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3cccc(S(=O)(=O)N4CCC(O)CC4)c3)cc12 CHEMBL3650294 IC50 81.0 nM
CNc1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911422 IC50 82.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc4c(c3)CCN4C(=O)C(C)C)cc12 CHEMBL3647457 IC50 83.0 nM
CCC(=O)N1CCc2cc(NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)ccc21 CHEMBL3647456 IC50 84.0 nM
COC(=O)c1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cn1 CHEMBL3647489 IC50 85.0 nM
COc1cc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)ccc1C(=O)N1CCN(C)CC1 CHEMBL3647504 IC50 85.0 nM
CNC(=O)c1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1OC CHEMBL3647507 IC50 85.0 nM
CSc1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911441 IC50 86.0 nM
COc1cc(NC(=O)c2cn(Cc3c(Cl)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc(OC)c1OC CHEMBL1911570 IC50 88.0 nM
CCOc1cc(N2CCN(C)CC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019115 IC50 88.0 nM
CCn1c(Nc2ccccc2C)nc2ccsc2c1=O CHEMBL3360155 IC50 88.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc4c(c3)CCN4)cc12 CHEMBL3647453 IC50 88.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CCC(N)CC3)cc12 CHEMBL3897753 IC50 88.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)Nc3ccc(N4CCC(O)CC4)c(F)c3)cc12 CHEMBL3650296 IC50 88.0 nM
COc1cc(/C=C/C(N)=O)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171438 IC50 89.0 nM
COc1ccc(Cn2c(=O)c3cc(OCCO)ccc3n(C3CCN(C=O)CC3)c2=O)cc1OC CHEMBL3646895 IC50 89.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)Nc3ccc(C(=O)N(C)C)cc3)cc12 CHEMBL3650286 IC50 89.0 nM
Cn1nc(-c2cccc(C(N)=O)c2)s/c1=N\C1CCCCC1 CHEMBL184016 IC50 90.0 nM
O=C(Nc1ccc(OC(F)(F)F)cc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O CHEMBL1911551 IC50 90.0 nM
Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)N(C)C CHEMBL484928 IC50 90.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)Nc3ccc(N4CCN(C)CC4)cc3)cc12 CHEMBL3650261 IC50 90.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NCCN3CC(=O)NC3=O)cc12 CHEMBL3650305 IC50 90.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCC(O)CC4)CC3)cc12 CHEMBL3650342 IC50 90.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CCC(C(=O)O)CC3)cc12 CHEMBL3941350 IC50 91.0 nM
COc1cc(CCC(N)=O)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171439 IC50 93.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)N[C@H]3CC[C@H](N4CCN(C)CC4=O)CC3)cc12 CHEMBL3650337 IC50 93.0 nM
O=C(Nc1ccccc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O CHEMBL1911425 IC50 94.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C(=O)N4CCN(C)CC4)cc3)cc12 CHEMBL3647461 IC50 95.0 nM
N#Cc1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911426 IC50 96.0 nM
CCN1C(=O)CN(CCNC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)C1=O CHEMBL3650306 IC50 97.0 nM
Cc1nn(C2CCOCC2)c2sc(C(=O)Nc3ccc(N4CCN(C)CC4=O)cc3)cc12 CHEMBL3650345 IC50 97.0 nM
CCn1c(NC2CCCC2)nc2c(C)csc2c1=O CHEMBL3354166 IC50 98.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc4c(c3)CCN4C(=O)C(C)(C)C)cc12 CHEMBL3647458 IC50 98.0 nM
Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N)cc3)cc12 CHEMBL3647486 IC50 99.0 nM
Cc1ccc(Cl)c2c1C1(CCCCC1)NC(=O)N2 CHEMBL363894 IC50 100.0 nM
NC1CCN(c2ccc(-c3nc4snc(C5CCCCC5)c4c(=O)[nH]3)c(F)c2)CC1 CHEMBL2019126 IC50 101.0 nM
Nc1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911423 IC50 104.0 nM
COc1cc(N2CCNCC2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 CHEMBL2171424 IC50 104.0 nM
O=C(Nc1ccc(O)cc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O CHEMBL1911442 IC50 105.0 nM
COc1cc(N2CCC(F)(F)CC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 CHEMBL2019116 IC50 106.0 nM
O=C1Nc2c(Cl)cc(Cl)cc2C2(CCCCC2)N1 CHEMBL184791 IC50 120.0 nM
Cn1nc(-c2ccc(C(N)=O)c(O)c2)s/c1=N\C1CCCCC1 CHEMBL183952 IC50 120.0 nM
O=C(Nc1ccc(N2CCCCC2)cc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O CHEMBL1911419 IC50 124.0 nM
CNC(=O)c1ccc(-c2nc3snc(C4CCCCC4)c3c(=O)[nH]2)c(OC)c1 CHEMBL2019117 IC50 125.0 nM
Cn1nc(-c2ccc(S(C)(=O)=O)cc2)s/c1=N\C1CCCCC1 CHEMBL185144 IC50 130.0 nM
COC(=O)c1cccc(-c2nn(C)/c(=N/C3CCCCC3)s2)c1 CHEMBL182294 IC50 140.0 nM
Cn1nc(-c2ccc(Cl)cc2)s/c1=N\c1cccc(C(=O)O)c1 CHEMBL185604 IC50 140.0 nM
Cn1nc(-c2ccc(Cl)cc2)s/c1=N\c1ccc(O)c(C(=O)O)c1 CHEMBL184017 IC50 150.0 nM
CN(C)CCOc1ccc(Cl)c2c1C1(CCCCC1)NC(=O)N2 CHEMBL184903 IC50 150.0 nM
Cn1nc(-c2ccc(S(N)(=O)=O)cc2)s/c1=N\C1CCCCC1 CHEMBL183119 IC50 150.0 nM
CCn1c(NC2CCCC2)nc2ccsc2c1=O CHEMBL3354160 IC50 150.0 nM
COc1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911443 IC50 151.0 nM
Cc1cc(Cl)c2c(c1)C1(CCCCC1)NC(=O)N2 CHEMBL185814 IC50 160.0 nM
COc1cc(Cl)c2c(c1)C1(CCCCC1)NC(=O)N2 CHEMBL185019 IC50 160.0 nM
Cn1nc(-c2ccc(Cl)cc2)s/c1=N\c1ccc(F)c(C(=O)O)c1 CHEMBL182574 IC50 160.0 nM
C=CCNc1nc2cc(-c3ccc(N4CCN(C(C)C)CC4)cc3)sc2c(=O)n1C CHEMBL3354155 IC50 160.0 nM
O=C(Nc1ccc(N2CCOCC2)cc1)c1cn(Cc2c(Cl)cccc2Cl)c2ccc(=O)[nH]c2c1=O CHEMBL1911558 IC50 165.0 nM
O=C1Nc2c(Cl)cccc2C2(CCCCC2)N1 CHEMBL185460 IC50 170.0 nM
CCn1c(NC(C)C)nc2c(C3CCN(C(C)C)CC3)csc2c1=O CHEMBL3403364 IC50 170.0 nM
O=C(O)Cc1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911432 IC50 176.0 nM
COc1cc(NC(=O)c2cn(Cc3ccccc3Cl)c3ccc(=O)[nH]c3c2=O)cc(OC)c1OC CHEMBL1911567 IC50 178.0 nM
O=C(Nc1ccc(F)cc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O CHEMBL1911428 IC50 179.0 nM
O=[N+]([O-])c1ccc(Sc2ccncc2)c(Cl)c1 CHEMBL3359633 IC50 180.0 nM
O=C(Nc1ccc(C(=O)N2CCOCC2)cc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O CHEMBL1911437 IC50 188.0 nM
CCn1c(NC(C)C)nc2c(C3CCNCC3)csc2c1=O CHEMBL3403363 IC50 190.0 nM
COc1cc(NC(=O)c2cn(Cc3ccc(F)cc3Cl)c3ccc(=O)[nH]c3c2=O)cc(OC)c1OC CHEMBL1911569 IC50 192.0 nM
Cn1nc(-c2cccc(S(N)(=O)=O)c2)s/c1=N\C1CCCCC1 CHEMBL184057 IC50 200.0 nM
O=C(O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc1 CHEMBL1911431 IC50 200.0 nM
COc1cc(NC(=O)c2cn(Cc3ccccc3F)c3ccc(=O)[nH]c3c2=O)cc(OC)c1OC CHEMBL1911550 IC50 206.0 nM
CNCC(O)COc1ccc(Cl)c2c1C1(CCCCC1)NC(=O)N2 CHEMBL364200 IC50 210.0 nM
CC1CCC2(CC1)NC(=O)Nc1c(Br)cccc12 CHEMBL185485 IC50 210.0 nM
COc1cc(NC(=O)c2cn(Cc3c(F)cccc3F)c3ccc(=O)[nH]c3c2=O)cc(OC)c1 CHEMBL1911552 IC50 212.0 nM
COC(=O)c1ccc(-c2nn(C)/c(=N/C3CCCCC3)s2)cc1 CHEMBL362264 IC50 230.0 nM
Cn1nc(-c2ccc(O)cc2)s/c1=N\C1CCCCC1 CHEMBL185439 IC50 240.0 nM
COc1cc2c(cc1OC)-c1c(-c3cnc(C(=O)N(C)C(C)(C)C)s3)ncn1CC2 CHEMBL2017057 Ki 243.0 nM
Cn1nc(-c2ccc(Cl)cc2)s/c1=N\c1cccc(C(=O)O)c1O CHEMBL182227 IC50 260.0 nM
Cc1ccccc1Cn1cc(C(=O)Nc2ccc(N3CCOCC3)cc2)c(=O)c2[nH]c(=O)ccc21 CHEMBL1911555 IC50 266.0 nM
COc1ccc2nc(C)c3c(C)nc(-c4sccc4C)n3c2n1 CHEMBL1915906 IC50 266.0 nM
COc1cc2c(cc1OC)-c1c(-c3cnc(C(=O)N4CCCOCC4)s3)ncn1CC2 CHEMBL2017060 Ki 269.0 nM
Cn1nc(-c2cccc(O)c2)s/c1=N\C1CCCCC1 CHEMBL367135 IC50 290.0 nM
CCn1c(Nc2ccccc2)nc2ccsc2c1=O CHEMBL3360154 IC50 290.0 nM
COc1c(OCc2ccc(F)cc2)cc2oc3cc4c(c(OC/C=C/C(=O)O)c3c(=O)c2c1CC=C(C)C)C=CC(C)(C)O4 CHEMBL4877549 IC50 298.0 nM
O=C(Nc1ccc(C(F)(F)F)cc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O CHEMBL1911430 IC50 300.0 nM
CCn1c(NC2CCC2)nc2ccsc2c1=O CHEMBL3403353 IC50 300.0 nM
C=CCNc1nc2cc(-c3ccc(C(=O)NCCCN(C)C)cc3)sc2c(=O)n1C CHEMBL3354157 IC50 310.0 nM
O=C(Nc1ccc(N2CCOCC2)cc1)c1cn(Cc2c(F)c(F)cc(F)c2F)c2ccc(=O)[nH]c2c1=O CHEMBL1911564 IC50 317.0 nM
COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)ccc4Cl)n3c2n1 CHEMBL1915891 IC50 332.0 nM
Nc1ccc(Sc2ccc(Cl)cc2[N+](=O)[O-])cc1 CHEMBL3359624 IC50 370.0 nM
CCn1c(NC(C)C)nc2ccsc2c1=O CHEMBL3403349 IC50 370.0 nM
CCn1c(NC2CCCC2)nc2c(-c3ccccc3C(=O)OC)csc2c1=O CHEMBL3354176 IC50 380.0 nM
O=C1Nc2c(F)cccc2C2(CCCCC2)N1 CHEMBL363075 IC50 390.0 nM
CN(C)CC(O)COc1ccc(Cl)c2c1C1(CCCCC1)NC(=O)N2 CHEMBL184013 IC50 400.0 nM
CCn1c(NC2CCOCC2)nc2ccsc2c1=O CHEMBL3403354 IC50 430.0 nM
Cn1nc(-c2ccc(Cl)cc2)s/c1=N\c1cccc(-c2noc(O)n2)c1 CHEMBL263311 IC50 440.0 nM
COc1cc(-c2nn(C)/c(=N/C3CCCCC3)s2)ccc1C(N)=O CHEMBL185173 IC50 470.0 nM
CN(C)CCN(C)C(=O)c1ccc(-c2nn(C)/c(=N/C3CCCCC3)s2)cc1 CHEMBL183040 IC50 470.0 nM
Fc1cccc(F)c1-n1c(=S)[nH]c2ccccc2c1=S CHEMBL3085803 IC50 480.0 nM
COc1cc2c(cc1OC)-c1c(-c3cnc(C(=O)NCc4ccccc4)s3)ncn1CC2 CHEMBL2017062 Ki 507.0 nM
CSc1nc2ccccc2c(=O)n1-c1c(F)cccc1F CHEMBL1236215 IC50 510.0 nM
CNc1nc(NC2(C#N)CCCCC2)nc(OC)n1 CHEMBL2402519 IC50 521.0 nM
CNc1nc(NC2(C#N)CCCCC2)nc(C2CC2)n1 CHEMBL2402517 IC50 539.0 nM
COc1ccc2nc(C)c3c(C)nc(-c4ccccc4C)n3c2n1 CHEMBL1915888 IC50 542.0 nM
Cn1nc(-c2ccc(C(=O)O)cc2)s/c1=N\C1CCCCC1 CHEMBL365634 IC50 550.0 nM
COc1cc2c(cc1OC)-c1c(-c3cnc(C(=O)NC4CCOCC4)s3)ncn1CC2 CHEMBL2017061 Ki 550.0 nM
Cn1nc(-c2ccc(N)cc2)s/c1=N\C1CCCCC1 CHEMBL362033 IC50 560.0 nM
CCOc1cc(C(=O)OCc2ccc(-c3ccc([N+](=O)[O-])cc3C)o2)cc(OCC)c1OCC CHEMBL2041586 IC50 580.0 nM
O=C1Nc2ccc(Cl)c(Cl)c2C2(CCCCC2)N1 CHEMBL362141 IC50 600.0 nM
O=c1c2ccccc2nc(SCc2ccccc2)n1-c1ccccc1 CHEMBL3088320 IC50 600.0 nM
COc1cc2c(cc1OC)-c1c(-c3cnc(C(=O)N4CCOCC4)s3)ncn1CC2 CHEMBL2017059 Ki 613.0 nM
COc1c(OCCCCCCC(=O)O)cc2oc3cc4c(c(O)c3c(=O)c2c1CC=C(C)C)C=CC(C)(C)O4 CHEMBL4471352 IC50 620.0 nM
CCn1c(Nc2ccncc2)nc2ccsc2c1=O CHEMBL3360163 IC50 630.0 nM
CN(C)C(=O)c1cccc(S(=O)(=O)N2CCS[C@H]2C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)c1 CHEMBL4075951 IC50 660.0 nM
COc1cc(NC(=O)c2cn(Cc3ccccc3)c3ccc(=O)[nH]c3c2=O)cc(OC)c1OC CHEMBL1911566 IC50 686.0 nM
Cn1nc(-c2cccc(Cl)c2)s/c1=N\C1CCCCC1 CHEMBL184416 IC50 700.0 nM
O=C(Nc1ccc(N2CCOCC2)cc1)c1cn(Cc2ccccc2)c2ccc(=O)[nH]c2c1=O CHEMBL1911554 IC50 712.0 nM
O=[N+]([O-])c1cc(Cl)ccc1Sc1ccncc1 CHEMBL3359635 IC50 720.0 nM
N#Cc1ccc(Oc2ccc3c(c2)COB3O)cc1 CHEMBL484785 IC50 730.0 nM
CCn1c(NC2CCCCC2)nc2ccsc2c1=O CHEMBL3354161 IC50 740.0 nM
O=C(Nc1ccc(N2CCOCC2)cc1)c1cn(Cc2ccccc2Cl)c2ccc(=O)[nH]c2c1=O CHEMBL1911557 IC50 767.0 nM
Cc1cccc2c1NC(=O)NC21CCCCC1 CHEMBL184081 IC50 790.0 nM
COc1ccc(Cn2c(=O)c3cc(CNC(C)=O)ccc3n(C3CCN(C=O)C3)c2=O)cc1OC CHEMBL3646896 IC50 820.0 nM
O=C(Nc1ccc(N2CCOCC2)cc1)c1cn(Cc2c(F)cccc2F)c2cccnc2c1=O CHEMBL1911416 IC50 823.0 nM
COc1ccc2nc(C)c3c(C)nc(-c4sc(C)nc4C)n3c2n1 CHEMBL1915912 IC50 824.0 nM
O=C1Nc2cccc(Cl)c2C2(CCCCC2)N1 CHEMBL361454 IC50 840.0 nM
CCOC(=O)c1sc(NC(=O)C(CC)OC(=O)C(CC(C)C)NC(=O)c2ccccc2)nc1C CHEMBL1404495 IC50 860.0 nM
COc1cc(NC(=O)c2cn(Cc3ccc(F)cc3)c3ccc(=O)[nH]c3c2=O)cc(OC)c1OC CHEMBL1911571 IC50 868.0 nM
Cn1nc(-c2cccc(C(=O)O)c2)s/c1=N\C1CCCCC1 CHEMBL359562 IC50 870.0 nM
CC1CCCCC1NC(=O)C(c1ccccc1Cl)N(CCc1ccccc1Cl)C(=O)CCl CHEMBL2041587 IC50 880.0 nM
Cc1cnccc1-c1nc(C)c2c(C)nc3ccc(OC(F)(F)F)cc3n12 CHEMBL1916106 IC50 919.0 nM
Cc1cc(-c2nn(C)/c(=N/C3CCCCC3)s2)ccc1C(N)=O CHEMBL184089 IC50 930.0 nM
CNCCOc1ccc(Cl)c2c1C1(CCCCC1)NC(=O)N2 CHEMBL184979 IC50 960.0 nM
O=C1Nc2ccc(-c3ccccc3)cc2C2(CCCCC2)N1 CHEMBL184781 IC50 980.0 nM
O=[N+]([O-])c1cc(Cl)ccc1Sc1ccccc1Br CHEMBL3359111 IC50 990.0 nM