Nc1nc(C(F)(F)F)nc2c1nnn2C[C@H]1CN(Cc2nccs2)CCO1 CHEMBL5169811 IC50 0.7 nM
Cc1cccc(CNC(=O)C2CN(Cc3nc(-c4ccccc4)oc3C)Cc3ccccc32)n1 CHEMBL1779976 IC50 1.8 nM
Cc1cccc(CNC(=O)C2CCCN(Cc3nc(-c4ccccc4)oc3C)C2)n1 CHEMBL1779978 IC50 1.8 nM
CC[C@@H]1C[C@@H](C(=O)NCc2cccc(C)n2)CN(Cc2nc(-c3ccccc3)oc2C)C1 CHEMBL1779984 IC50 1.8 nM
Cc1nc(N)c2nnn(C[C@H]3CN(Cc4nccs4)CCO3)c2n1 CHEMBL2070735 IC50 1.9 nM
C[C@@H](c1cc(OCC(F)F)ccn1)n1cnc2c(N)nc(Cl)nc21 CHEMBL4762103 IC50 10.0 nM
N#Cc1cc(Cn2c(=O)c3cc(OC(CF)CF)ccc3n(C3CCN(C=O)CC3)c2=O)ccc1-c1ccccc1 CHEMBL3646900 IC50 15.0 nM
CC(c1cc(OCC(F)F)ccn1)n1cnc2c(N)nc(Cl)nc21 CHEMBL4753446 IC50 26.0 nM
Nc1nc(Cl)nc2c1ncn2Cc1cccc(C2CCCC2)n1 CHEMBL4790482 IC50 46.0 nM
Nc1nc(Cl)nc2c1ncn2Cc1cccc(-c2ccccc2F)n1 CHEMBL4800434 IC50 130.0 nM
COc1ccc(Cn2c(=O)c3cc(OC(CF)CF)ccc3n(C3CCN(C=O)CC3)c2=O)cc1OC CHEMBL3646893 IC50 140.0 nM
COc1c(OCC2CC2)cc2oc3cc4c(c(OCc5ccncc5)c3c(=O)c2c1CC=C(C)C)C=CC(C)(C)O4 CHEMBL5407967 IC50 194.0 nM
Nc1nc(Cl)nc2c1ncn2Cc1cccc(C2CCOCC2)n1 CHEMBL4789101 IC50 220.0 nM
Nc1nc(Cl)nc2c1ncn2Cc1cccc(-c2ccco2)n1 CHEMBL4778928 IC50 240.0 nM
Nc1nc(Cl)nc2c1ncn2Cc1cccc(C2=CCCC2)n1 CHEMBL4798107 IC50 250.0 nM
Nc1nc(Cl)nc2c1ncn2Cc1cccc(C2=CCOCC2)n1 CHEMBL4745958 IC50 250.0 nM
CCc1nnc2c3ccccc3nc(Nc3cccc(C(=O)O)c3)n12 CHEMBL5288859 IC50 280.0 nM
Nc1nc(Cl)nc2c1ncn2Cc1cc(OCC(F)F)ccn1 CHEMBL4757863 IC50 360.0 nM
COc1cc(Cn2c(=O)c3cc(OC(CF)CF)ccc3n(C3CCN(C=O)CC3)c2=O)ccc1OCC(=O)N1CCCCC1 CHEMBL3646899 IC50 390.0 nM
Nc1nc(Cl)nc2c1ncn2Cc1cc(Cl)ccn1 CHEMBL4747327 IC50 410.0 nM
COc1ccnc(Cn2cnc3c(N)nc(Cl)nc32)c1 CHEMBL4750412 IC50 660.0 nM
COc1c(OCc2ccc(F)cc2)cc2oc3cc4c(c(OC/C=C/C(=O)O)c3c(=O)c2c1CC=C(C)C)C=CC(C)(C)O4 CHEMBL4877549 IC50 710.0 nM
CCn1c(=O)c2c(c3ccc(C)nc31)O[C@@](C)(CCO)C[C@H]2C=C(C)C CHEMBL5171560 IC50 820.0 nM
Nc1nc(Cl)nc2c1ncn2Cc1cccc(OCC(F)F)n1 CHEMBL4786234 IC50 920.0 nM