Cc1nc(NC(C)c2cccc(OCC(=O)N3CCC3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3728960 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(=O)N3CCCCC3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732835 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(Cl)c(COC(C)C(=O)O)c2)n1 CHEMBL3728070 IC50 0.0 nM
CC(=O)N1CCCC(COc2cccc(C(C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)C1 CHEMBL3728106 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(N)=O)c2)cc(-c2cc3ccccc3n2C)n1 CHEMBL3730833 IC50 0.0 nM
CCN(CC)C(=O)COc1cccc(C(C)Nc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 CHEMBL3733180 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc(Cl)cc2)n1 CHEMBL3728687 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2cccc(F)c2)n1 CHEMBL3730085 IC50 0.0 nM
COc1cccc(-c2cc(NC(C)c3cccc(-c4cnn(C)c4)c3)nc(C)n2)c1 CHEMBL3731070 IC50 0.0 nM
Cc1nc(NCc2c(F)cccc2Cl)cc(-c2ccc3ncsc3c2)n1 CHEMBL3727607 IC50 0.0 nM
Cc1nc(NC[C@H](C)c2ccccc2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3731927 IC50 0.0 nM
Cc1nc(NCCc2cccnc2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3728755 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-n3cnnn3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731413 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-n3cnnc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731213 IC50 0.0 nM
Cc1nc(NC(C)c2cccc([N+](=O)[O-])c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3727869 IC50 0.0 nM
COc1cc(-c2cc(N[C@@H]3CCCc4ccccc43)nc(C)n2)ccc1C CHEMBL3730462 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-n3ccnn3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3728952 IC50 0.0 nM
C=CC(=O)Nc1cccc(C(C)Nc2cc(-c3ccc4occ(C)c4c3)nc(C)n2)c1 CHEMBL3731615 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3ccn(C)c3c2)n1 CHEMBL3733357 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(N)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731074 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-n3nnnc3C)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3731774 IC50 0.0 nM
C#CCOc1cc(-c2cc(N[C@@H]3CCCc4ccccc43)nc(C)n2)ccc1C CHEMBL3732968 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-n3cnnn3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730680 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-n3cnnc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732994 IC50 0.0 nM
CCN(CC)C(=O)C(C)Oc1cccc(C(C)Nc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 CHEMBL3730814 IC50 0.0 nM
Cc1nc(NC2CCNc3ccccc32)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730020 IC50 0.0 nM
Cc1nc(NC2CCN(C)c3ccccc32)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729716 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncnc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732936 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732715 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccc(N)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731875 IC50 0.0 nM
CCOC(=O)Cn1cc(-c2cccc([C@H](C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)cn1 CHEMBL3729778 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(C)(C)O)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731800 IC50 0.0 nM
CC(=O)COc1cccc(C(C)Nc2cc(-c3ccc4occ(C)c4c3)nc(C)n2)c1 CHEMBL3732494 IC50 0.0 nM
CCc1coc2ccc(-c3cc(N[C@@H]4CCCc5ccccc54)nc(C)n3)cc12 CHEMBL3729019 IC50 0.0 nM
Cc1nc(N[C@@H]2CCOc3ccccc32)cc(-c2ccc3sccc3c2)n1 CHEMBL3730536 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnn(CC(=O)O)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731988 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncnc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732679 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2cc3ccccc3n2C)n1 CHEMBL3728410 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCc3noc(C)n3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3727501 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnc(N)nc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730238 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2cnc3ccn(C)c3c2)n1 CHEMBL3727784 IC50 0.0 nM
CCOC(=O)Cn1cc(-c2cccc([C@H](C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)cn1 CHEMBL3730278 IC50 0.0 nM
COc1cccc([C@H](C)Nc2cc(-c3cc(F)c4occc4c3)nc(C)n2)c1 CHEMBL3729446 IC50 0.0 nM
CCN1CCOc2ccc(-c3cc(N[C@@H]4CCCc5ccccc54)nc(C)n3)cc21 CHEMBL3729750 IC50 0.0 nM
CCN1CCCC(COc2cccc(C(C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)C1 CHEMBL3729193 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3ccc(N)nc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729521 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC3CCCN(C)C3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729549 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC3CCCNC3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3727699 IC50 0.0 nM
CC(=O)COc1cccc(C(C)Nc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 CHEMBL3732712 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3csc(C)n3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3728696 IC50 0.0 nM
Cc1cc(COc2cncc(C(C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)n(C)n1 CHEMBL3732067 IC50 0.0 nM
CCN(CC)C(=O)COc1ccc(F)c(CNc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 CHEMBL3731398 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(C)O)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730532 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(C)(C)O)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729834 IC50 0.0 nM
Cc1nc(NC(C)c2ccccc2F)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730773 IC50 0.0 nM
COc1cccc([C@H](C)Nc2cc(-c3ccc4[nH]ccc4c3)nc(C)n2)c1 CHEMBL3728185 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3[nH]ccc3c2)n1 CHEMBL3730588 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(O)c2)cc(-c2ccc3ccn(C)c3c2)n1 CHEMBL3728086 IC50 0.0 nM
COc1cccc([C@H](C)Nc2cc(-c3ccc4c(c3)OCO4)nc(C)n2)c1 CHEMBL3729430 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(S(N)(=O)=O)c2)cc(-c2ccc3ccn(C)c3c2)n1 CHEMBL3731531 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3ccn(C)c3c2)n1 CHEMBL3728575 IC50 0.0 nM
CCN(CC)C(=O)COc1cccc(C(C)Nc2cc(-c3ccc4ccn(C)c4c3)nc(C)n2)c1 CHEMBL3728357 IC50 0.0 nM
COc1cccc([C@H](C)Nc2cc(-c3cccc(OC)c3Cl)nc(C)n2)c1 CHEMBL3732906 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3cc[nH]c3c2)n1 CHEMBL3727454 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2ccccc2)cc(-c2ccc3ccn(C)c3c2)n1 CHEMBL3728502 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2ccc(F)cc2)cc(-c2ccc3ccn(C)c3c2)n1 CHEMBL3733003 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(S(=O)(=O)NCC#N)c2)cc(-c2ccc3ccn(C)c3c2)n1 CHEMBL3727669 IC50 0.0 nM
CCNC(=O)COc1cccc(C(C)Nc2cc(-c3ccc4ccn(C)c4c3)nc(C)n2)c1 CHEMBL3730575 IC50 0.0 nM
CCn1ccc2ccc(-c3cc(N[C@@H]4CCCc5ccccc54)nc(C)n3)cc21 CHEMBL3729675 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(=O)N(C)C)c2)cc(-c2ccc3ccn(C)c3c2)n1 CHEMBL3731619 IC50 0.0 nM
Cc1nc(N[C@@H]2CCOc3ccccc32)cc(-c2ccc3ccn(C)c3c2)n1 CHEMBL3733262 IC50 0.0 nM
COc1cccc([C@H](C)Nc2cc(-c3ccc4ccn(C)c4c3)nc(C)n2)c1 CHEMBL3728457 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCCCC(=O)O)c2)cc(-c2ccc3ccn(C)c3c2)n1 CHEMBL3732562 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3c(c2)OCO3)n1 CHEMBL3729185 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(=O)N3CCOCC3)c2)cc(-c2ccc3ccn(C)c3c2)n1 CHEMBL3732481 IC50 0.0 nM
Cc1nc(NC2CCOc3ccccc32)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730022 IC50 0.0 nM
Cc1nc(NC2CCSc3ccccc32)cc(-c2ccc3ncsc3c2)n1 CHEMBL3731328 IC50 0.0 nM
Cc1nc(NC2CSCc3ccccc32)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730684 IC50 0.0 nM
CC(=O)Nc1ccc2c(c1)CCCC2Nc1cc(-c2ccc3ncsc3c2)nc(C)n1 CHEMBL3728964 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccoc2)n1 CHEMBL3733202 IC50 0.0 nM
COc1cccc([C@H](C)Nc2cc(-c3ccccc3)nc(C)n2)c1 CHEMBL3731708 IC50 0.0 nM
CCc1cccc(-c2cc(N[C@@H](C)c3cccc(OC)c3)nc(C)n2)c1 CHEMBL3733301 IC50 0.0 nM
Cc1nc(NC2CCCc3cc(N)ccc32)cc(-c2ccc3ncsc3c2)n1 CHEMBL3727615 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3c(c2)CCO3)n1 CHEMBL3728534 IC50 0.0 nM
Cc1nc(/C=C/c2ccccc2)cc(N[C@@H]2CCCc3ccccc32)n1 CHEMBL3727566 IC50 0.0 nM
Cc1nc(NC2CCOc3ccc(F)cc32)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729249 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(CO)cc2)n1 CHEMBL3728160 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccccc2)n1 CHEMBL3729801 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(O)cc2)n1 CHEMBL3729936 IC50 0.0 nM
Cc1nc(NC2c3ccccc3CCC2C)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732427 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2cc3ccccc3o2)n1 CHEMBL3729555 IC50 0.0 nM
COc1ccc(-c2cc(N[C@@H]3CCCc4ccccc43)nc(C)n2)cc1OC CHEMBL3728827 IC50 0.0 nM
Cc1cc(COc2cccc(C(C)Nc3cc(-c4ccc5ccn(C)c5c4)nc(C)n3)c2)n(C)n1 CHEMBL3730672 IC50 0.0 nM
Cc1cc(COc2cccc([C@H](C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)n(C)n1 CHEMBL3733312 IC50 0.0 nM
Cc1nc(NC(C)c2ccc(F)c(O)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728117 IC50 0.0 nM
Cc1nc(NC(C)c2ccc(F)c(-c3cnn(C)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728904 IC50 0.0 nM
COc1cccc(-c2cc(NC(C)c3cccc(OCc4cc(C)nn4C)c3)nc(C)n2)c1Cl CHEMBL3728574 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(O)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732922 IC50 0.0 nM
COc1cc(-c2cc(NC(C)c3cccc(OCc4cc(C)nn4C)c3)nc(C)n2)ccc1C CHEMBL3728671 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(S(=O)(=O)NCC#N)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3727895 IC50 0.0 nM
CC#CCNS(=O)(=O)c1cccc(C(C)Nc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 CHEMBL3731033 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC#N)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3727468 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(=O)N3CCCCCC3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3733211 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(=O)NC(C)C)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732635 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(=O)N3CC3C)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3731414 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(=O)N(C)C)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3731571 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(S(N)(=O)=O)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729286 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(=O)N3CCN(c4ccccn4)CC3)c2)cc(-c2ccc3ccn(C)c3c2)n1 CHEMBL3728709 IC50 0.0 nM
COC(=O)C1CCN(C(=O)COc2cccc(C(C)Nc3cc(-c4ccc5ccn(C)c5c4)nc(C)n3)c2)CC1 CHEMBL3729056 IC50 0.0 nM
CNC(=O)COc1cccc(C(C)Nc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 CHEMBL3728216 IC50 0.0 nM
CCNC(=O)COc1cccc(C(C)Nc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 CHEMBL3727753 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(C(N)=O)cc2)n1 CHEMBL3727572 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(Cl)c(N)c2)n1 CHEMBL3729898 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2cccc(C#N)c2)n1 CHEMBL3730380 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccccc2C)n1 CHEMBL3728403 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2cccc(N(C)C)c2)n1 CHEMBL3729779 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2cccc(F)c2)n1 CHEMBL3731473 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(C(F)(F)F)cc2)n1 CHEMBL3731150 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(Cl)c(C#N)c2)n1 CHEMBL3729039 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(Cl)c(F)c2)n1 CHEMBL3730214 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(C)c(NCC#N)c2)n1 CHEMBL3731592 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(Cl)c(Cl)c2)n1 CHEMBL3731164 IC50 0.0 nM
CNc1cc(-c2cc(N[C@@H]3CCCc4ccccc43)nc(C)n2)ccc1C CHEMBL3727839 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(Cl)cc2)n1 CHEMBL3732595 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(Cl)c(N(C)C)c2)n1 CHEMBL3730140 IC50 0.0 nM
Cc1ccc(-c2cc(N[C@@H]3CCCc4ccccc43)nc(C)n2)cc1 CHEMBL3731466 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(Cl)c(NCC#N)c2)n1 CHEMBL3730529 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(C(N)=O)c(F)c2)n1 CHEMBL3728839 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(Cl)c(C)c2)n1 CHEMBL3732946 IC50 0.0 nM
CNc1cc(-c2cc(N[C@@H]3CCCc4ccccc43)nc(C)n2)ccc1Cl CHEMBL3731256 IC50 0.0 nM
COc1cccc([C@H](C)Nc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 CHEMBL3729661 IC50 0.0 nM
CCC(C)CNc1cc(-c2ccc3ncsc3c2)nc(C)n1 CHEMBL3728919 IC50 0.0 nM
COc1cccc([C@H](C)Nc2cc(-c3ccc(Cl)cc3)nc(C)n2)c1 CHEMBL3733331 IC50 0.0 nM
COc1cccc([C@H](C)Nc2cc(-c3ccc(C)cc3)nc(C)n2)c1 CHEMBL3732442 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(C)c(N)c2)n1 CHEMBL3728209 IC50 0.0 nM
COc1cccc([C@H](C)Nc2cc(-c3ccc4sccc4c3)nc(C)n2)c1 CHEMBL3732363 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3ncn(C)c3c2)n1 CHEMBL3728195 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3c(c2)OCCO3)n1 CHEMBL3733284 IC50 0.0 nM
COc1cccc([C@H](C)Nc2cc(-c3ccc4occc4c3)nc(C)n2)c1 CHEMBL3729097 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3ncoc3c2)n1 CHEMBL3730111 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3c(c2)N(C)CC3)n1 CHEMBL3729361 IC50 0.0 nM
COc1cccc([C@H](C)Nc2cc(-c3ccc4occ(C)c4c3)nc(C)n2)c1 CHEMBL3729670 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3c(c2)N(C)CCO3)n1 CHEMBL3730530 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730737 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3sccc3c2)n1 CHEMBL3731514 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3occc3c2)n1 CHEMBL3730587 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729404 IC50 0.0 nM
CNC(=O)COc1cccc(C(C)Nc2cc(-c3ccc4ccn(C)c4c3)nc(C)n2)c1 CHEMBL3728592 IC50 0.0 nM
CC(=O)N1CCN(CCOc2cccc(C(C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)CC1 CHEMBL3731349 IC50 0.0 nM
Cc1nc(NCc2cc(OCC(=O)N(C)C)ccc2F)cc(-c2ccc3ncsc3c2)n1 CHEMBL3731890 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(CC(=O)O)c3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730485 IC50 0.0 nM
COCCNC(=O)COc1cccc(C(C)Nc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 CHEMBL3729799 IC50 0.0 nM
Cc1nc(NCc2cc(OCC(=O)N3CCOCC3)ccc2F)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730840 IC50 0.0 nM
CCN(CC)C(=O)COc1cccc(C(C)Nc2cc(-c3ccc4c(c3)N(C)CCO4)nc(C)n2)c1 CHEMBL3729266 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(Cl)c(CO)c2)n1 CHEMBL3731440 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(C)c(Cl)c2)n1 CHEMBL3729068 IC50 0.0 nM
Cc1nc(N[C@@H]2CCOc3ccccc32)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3733056 IC50 0.0 nM
CCN(CC)C(=O)COc1cccc(C(C)Nc2cc(-c3ccc4occ(C)c4c3)nc(C)n2)c1 CHEMBL3732820 IC50 0.0 nM
C#CCNc1cc(-c2cc(N[C@@H]3CCCc4ccccc43)nc(C)n2)ccc1Cl CHEMBL3727541 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCCn3ccnc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730686 IC50 0.0 nM
CCn1cc(-c2cccc([C@H](C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)cn1 CHEMBL3728169 IC50 0.0 nM
Cc1nc(N[C@@H]2CCOc3ccccc32)cc(-c2ccc(Cl)c(C)c2)n1 CHEMBL3728564 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC3CCCNC3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730190 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccnn3C)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731743 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCCO)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729048 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(OCC(=O)N3CCOCC3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729971 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCCCN(C)C)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731279 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCc3ccn(C)n3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728583 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(O)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731046 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(Br)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730496 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cn[nH]c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729949 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(O)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728770 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cccn3C)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731228 IC50 0.0 nM
Cc1nc(N[C@@H]2CCOc3ccccc32)cc(-c2ccc3c(c2)N(C)CCO3)n1 CHEMBL3729829 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2ccccc2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731229 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cccnc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729498 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3733066 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2ccc(F)cc2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3733199 IC50 0.0 nM
Cc1cc(COc2cccc(C(C)Nc3cc(-c4ccc5occc5c4)nc(C)n3)c2)n(C)n1 CHEMBL3730166 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccnn3C)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3731685 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(F)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729968 IC50 0.0 nM
CCn1cc(-c2cccc([C@H](C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)cn1 CHEMBL3728910 IC50 0.0 nM
C#CCNc1cc(-c2cc(N[C@@H]3CCCc4ccccc43)nc(C)n2)ccc1C CHEMBL3729680 IC50 0.0 nM
Cc1nc(N[C@H](C)c2cccc(OCC(=O)N3CCOCC3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729903 IC50 0.0 nM
Cc1nc(N[C@@H]2CCOc3ccccc32)cc(-c2ccc(C)c(NCC#N)c2)n1 CHEMBL3730107 IC50 0.0 nM
Cc1nc(N[C@H](C)c2cccc(O)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729789 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cn[nH]c3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3727826 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCS(C)(=O)=O)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730093 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(F)c(NCC#N)c2)n1 CHEMBL3733075 IC50 0.0 nM
COc1cc(-c2cc(N[C@@H]3CCCc4ccccc43)nc(C)n2)ccc1C(N)=O CHEMBL3728363 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCCn3ccnc3C)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732714 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCCCCO)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732145 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(O)CO)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730877 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCCO)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3731052 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCCCO)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730603 IC50 0.0 nM
CCN(CC)CCCOc1cccc(C(C)Nc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 CHEMBL3733132 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCCCN3CCOCC3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732567 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(=O)NCCO)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3731588 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(=O)NC3CC3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732261 IC50 0.0 nM
CCN(CC)C(=O)COc1cccc(C(C)Nc2cc(-c3ccc4ccccc4c3)nc(C)n2)c1 CHEMBL3732570 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCCCN3CCCC3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732337 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3ncccc3c2)n1 CHEMBL3728264 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3nccnc3c2)n1 CHEMBL3729673 IC50 0.0 nM
Cc1nc(N[C@@H]2CCOc3ccccc32)cc(-c2ccc(Cl)c(N)c2)n1 CHEMBL3729777 IC50 0.0 nM
Cc1nc(NCc2ccccc2Cl)cc(-c2ccc3ncsc3c2)n1 CHEMBL3728539 IC50 0.0 nM
Cc1nc(NCc2c(F)ccc(C)c2Cl)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729887 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730063 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3728460 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(OCC(=O)N(C)C)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731409 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCCN(C)C)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728811 IC50 0.0 nM
Cc1nc(N[C@H](C)c2cccc(OCC(=O)N(C)C)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732242 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCCN(C)C)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3728085 IC50 0.0 nM
Cc1ccc(C)c(-c2cc(NC(C)c3cccc(-c4cnn(C)c4)c3)nc(C)n2)c1 CHEMBL3733107 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc(Cl)c(Cl)c2)n1 CHEMBL3727790 IC50 0.0 nM
CCCC(C)Nc1cc(-c2ccc3ncsc3c2)nc(C)n1 CHEMBL3728820 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(Br)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732068 IC50 0.0 nM
CCNC(=O)/C=C/c1cccc([C@H](C)Nc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 CHEMBL3729824 IC50 0.0 nM
CCCNC(=O)COc1cccc(C(C)Nc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 CHEMBL3728213 IC50 0.0 nM
CCN(C)C(=O)COc1cccc(C(C)Nc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 CHEMBL3727524 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc(C)c(OCC#N)c2)n1 CHEMBL3728066 IC50 0.0 nM
Cc1nc(CCc2ccccc2)cc(N[C@@H]2CCCc3ccccc32)n1 CHEMBL3729061 IC50 0.0 nM
COc1ccc([C@H](C)Nc2cc(-c3ccc4occ(C)c4c3)nc(C)n2)cc1 CHEMBL3730028 IC50 0.0 nM
Cc1cc(COc2cccc(C(C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)n(C)n1 CHEMBL3728912 IC50 0.0 nM
Cc1cc(COc2cccc(C(C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)on1 CHEMBL3730783 IC50 0.0 nM
Cc1nc(N[C@@H]2CCCc3ccccc32)cc(-c2ccc3c(c2)C(=O)C=CC3)n1 CHEMBL3730106 IC50 0.0 nM
CCC(=O)Nc1ccc2c(c1)CCCC2Nc1cc(-c2ccc3ncsc3c2)nc(C)n1 CHEMBL3731578 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCCn3ccnc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729856 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(N)=O)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732221 IC50 0.0 nM
Cc1cc(COc2cccc(C(C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)n(C)n1 CHEMBL3727850 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(N)=O)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3728255 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(=O)N3CCOCC3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730918 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(=O)N(C)C)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731534 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCc3ccn(C)n3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3728885 IC50 0.0 nM
Cc1nc(NC(C)c2ccc(F)c(-c3cnc(N)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729035 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2ccc(F)c(-c3cnn(C)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732701 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cncc(C(N)=O)c3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3728799 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCN(C)CC4)nc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730861 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(NCC(C)(C)CO)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732742 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-n3cccn3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732641 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-n3nccn3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731539 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3sccc3c2)n1 CHEMBL3730573 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnc(NCCN(C)C)nc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730429 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-n3cnnn3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3727628 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(Br)c2)cc(-c2ccc3scc(C)c3c2)n1 CHEMBL3728426 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccc(F)nc3)c2)cc(-c2ccc3scc(C)c3c2)n1 CHEMBL3731121 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(F)c3)c2)cc(-c2ccc3scc(C)c3c2)n1 CHEMBL3730150 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N)nc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729255 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(F)c3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732915 IC50 0.0 nM
Cc1ccc(-c2cccc([C@H](C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)cn1 CHEMBL3732165 IC50 0.0 nM
CCc1coc2ccc(-c3cc(N[C@@H](C)c4cccc(-c5cnc(N)nc5)c4)nc(C)n3)cc12 CHEMBL3732258 IC50 0.0 nM
Cc1cncc(-c2cccc([C@H](C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)c1 CHEMBL3728162 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(F)c(C)c3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732203 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccc(F)nc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730114 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(F)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3733010 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2cc(F)c3occc3c2)n1 CHEMBL3729736 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(Cl)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730444 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(Cl)nc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3731786 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccc(F)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728172 IC50 0.0 nM
CNc1ncc(-c2cccc([C@H](C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)cn1 CHEMBL3729702 IC50 0.0 nM
CNc1ncc(-c2cccc([C@H](C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)cn1 CHEMBL3728545 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N)nc3)c2)cc(-c2cc(F)c3occc3c2)n1 CHEMBL3732530 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N(C)C)nc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3727811 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N(C)C)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729142 IC50 0.0 nM
CCNc1ncc(-c2cccc([C@H](C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)cn1 CHEMBL3731563 IC50 0.0 nM
CCNc1ncc(-c2cccc([C@H](C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)cn1 CHEMBL3730509 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCOCC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3727614 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCNCC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728794 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(N)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728602 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(NCCO)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729257 IC50 0.0 nM
CCN(CC)c1ncc(-c2cccc([C@H](C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)cn1 CHEMBL3730310 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(Cl)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3727512 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(NCc4ccco4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730824 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(Cl)c(N)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728832 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cccnc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732390 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccc(N(C)C)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3733018 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3ccc(N4CCNCC4)nc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732333 IC50 0.0 nM
Cc1nc(NC(C)c2cncc(-c3cnn(C)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732692 IC50 0.0 nM
Cc1ccc(-c2cccc([C@H](C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)cn1 CHEMBL3729009 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccc(N4CCNCC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728840 IC50 0.0 nM
Cc1cncc(-c2cccc([C@H](C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)c1 CHEMBL3729814 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(F)c(C)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730900 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccnc(F)c3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3731486 IC50 0.0 nM
Cc1nc(NC(C)c2ccnc(-c3cnc(N)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732515 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccc(Cl)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731613 IC50 0.0 nM
CNc1ccc(-c2cccc([C@H](C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)cn1 CHEMBL3731371 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccc(N4CCOCC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728933 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccc(NCCO)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729219 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3occc3c2)n1 CHEMBL3727928 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2ccnc(-c3cnn(C)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3727921 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc(Cl)c(F)c2)n1 CHEMBL3731580 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnn(C)c3)c2)cc(-c2cccc(F)c2)n1 CHEMBL3731698 IC50 0.0 nM
COc1cncc(-c2cccc(C(C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)c1 CHEMBL3733267 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnc(F)nc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729244 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnc(C#N)nc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3728630 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cncc(C#N)c3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3728792 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnccc3Cl)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729124 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(NCC4CCCO4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730614 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cncc(-c3cnn(C)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3727496 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N)nc3)c2)cc(-c2ccc3scc(C)c3c2)n1 CHEMBL3732385 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(N)c3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730721 IC50 0.0 nM
COc1cccc([C@H](C)Nc2cc(-c3ccc(C)c(OC)c3)nc(C)n2)c1 CHEMBL3731886 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCc3cc[nH]n3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732257 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCc3ccon3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3727474 IC50 0.0 nM
COc1cc(-c2cc(NC(C)c3cccc(OCc4ccn(C)n4)c3)nc(C)n2)ccc1C CHEMBL3732016 IC50 0.0 nM
Cc1nc(NC(C)c2ccc(F)c(OCc3ccnn3C)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3733124 IC50 0.0 nM
COc1cc(-c2cc(NC(C)c3cccc(OCC(N)=O)c3)nc(C)n2)ccc1C CHEMBL3731585 IC50 0.0 nM
C#CCNS(=O)(=O)c1cccc(C(C)Nc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 CHEMBL3728738 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3[nH]ccc3c2)n1 CHEMBL3730102 IC50 0.0 nM
Cc1cccc(-c2cc(NC(C)c3cccc(-c4cnn(C)c4)c3)nc(C)n2)c1 CHEMBL3731706 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccccc2)n1 CHEMBL3727439 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(C#N)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729363 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OC(C)(C)C(N)=O)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732610 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3noc(C)n3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729759 IC50 0.0 nM
Cc1cccc(C(C)Nc2cc(-c3ccc4occ(C)c4c3)nc(C)n2)c1 CHEMBL3731084 IC50 0.0 nM
Cc1cc(COc2cccc(C(C)Nc3cc(-c4cc5ccccc5n4C)nc(C)n3)c2)n(C)n1 CHEMBL3731331 IC50 0.0 nM
Cc1ccc([C@H](C)Nc2cc(-c3ccc4occ(C)c4c3)nc(C)n2)cc1 CHEMBL3729294 IC50 0.0 nM
CCc1coc2ccc(-c3cc(NC(C)c4cccc(OCc5cc(C)nn5C)c4)nc(C)n3)cc12 CHEMBL3732772 IC50 0.0 nM
CCc1coc2ccc(-c3cc(N[C@@H](C)c4cccc(OC)c4)nc(C)n3)cc12 CHEMBL3727580 IC50 0.0 nM
Cc1nc(N[C@H](C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729623 IC50 0.0 nM
COc1cccc(CNc2cc(-c3ccc4occ(C)c4c3)nc(C)n2)c1 CHEMBL3727563 IC50 0.0 nM
CCc1coc2ccc(-c3cc(NC(C)c4cccc(O)c4)nc(C)n3)cc12 CHEMBL3729625 IC50 0.0 nM
Cc1nc(NC(C)c2ccnc(Cl)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3727892 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCc3noc(C)n3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3727985 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3c(c2)N(C)CCO3)n1 CHEMBL3728844 IC50 0.0 nM
CCc1coc2ccc(-c3cc(NC(C)c4cccc(-c5cnn(C)c5)c4)nc(C)n3)cc12 CHEMBL3730347 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccn[nH]3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3727636 IC50 0.0 nM
COc1cccc([C@@H](C)Nc2cc(-c3ccc4occ(C)c4c3)nc(C)n2)c1 CHEMBL3731006 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cccn3C)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729147 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCc3ccn(C)n3)c2)cc(-c2ccc3occc3c2)n1 CHEMBL3732847 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccccc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732896 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(N3CCOCC3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3731294 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccccc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3731989 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(O)CF)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3733031 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(Br)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732184 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCCCC(=O)N(C)C)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730973 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCCn3cccc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3731372 IC50 0.0 nM
CCc1ccc(-c2cc(NC(C)c3cccc(-c4cnn(C)c4)c3)nc(C)n2)cc1 CHEMBL3730004 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccn[nH]3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729678 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCC(=O)NCCN(C)C)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730221 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3ccoc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729627 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCc3ccccc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3728565 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3ccsc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730144 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCc3cccnc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3728631 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCc3csc(C)n3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729518 IC50 0.0 nM
CCCOc1cccc(C(C)Nc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 CHEMBL3733143 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(OCCF)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730857 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cncc(C(F)(F)F)c3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729929 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCN(C)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730065 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(NCCCO)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731362 IC50 0.0 nM
COC(=O)CNc1ncc(-c2cccc(C(C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)cn1 CHEMBL3727708 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccc(N4CCN(C)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731665 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(NCC(=O)O)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729536 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(NCC(=O)CO)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728922 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cncc(-c3cncc(F)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731234 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cncc(-c3ccc(F)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730964 IC50 0.0 nM
CCn1cc(-c2cncc([C@H](C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)cn1 CHEMBL3728590 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cncc(-c3cnc(Cl)c(N)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728911 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cncc(-c3cnc(N)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732942 IC50 0.0 nM
Cc1nc(NC(C)c2cc(F)cc(Br)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732540 IC50 0.0 nM
Cc1nc(NC(C)c2cc(F)cc(-c3cnc(N)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728971 IC50 0.0 nM
Cc1nc(NC(C)c2cc(F)cc(-c3cnn(C)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729910 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cncc(-c3cnc(N4CCC(O)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731392 IC50 0.0 nM
Cc1nc(NC(C)c2cc(F)cc(-c3cnc(Cl)c(N)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729110 IC50 0.0 nM
Cc1nc(NC(C)c2ccc(C)c(Br)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732580 IC50 0.0 nM
Cc1nc(NC(C)c2ccc(C)c(-c3cnc(N)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3727388 IC50 0.0 nM
Cc1nc(NC(C)c2ccc(C)c(-c3cnn(C)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731258 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N)nc3)c2)cc(-c2ccc3ccn(C)c3c2)n1 CHEMBL3729349 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cncc(-c3ccnn3C)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729732 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cncc(-c3cn[nH]c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3733196 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(NC[C@H](O)CO)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730119 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3c(c2)OCCO3)n1 CHEMBL3729096 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCN(CCN(C)C)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732935 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCN(CCO)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729935 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCN(Cc5nccn5C)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731723 IC50 0.0 nM
COCCN1CCN(c2ncc(-c3cccc([C@H](C)Nc4cc(-c5ccc6occ(C)c6c5)nc(C)n4)c3)cn2)CC1 CHEMBL3728705 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCN(CCOCCO)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730251 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCN(CCN5CCOCC5)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3733282 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3scc(C)c3c2)n1 CHEMBL3728550 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(N)c3)c2)cc(-c2ccc3scc(C)c3c2)n1 CHEMBL3727782 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N)nc3)c2)cc(-c2ccc3occ(Cl)c3c2)n1 CHEMBL3733041 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(Cl)c3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3727634 IC50 0.0 nM
CCN1CCN(c2ncc(-c3cccc([C@H](C)Nc4cc(-c5ccc6ncsc6c5)nc(C)n4)c3)cn2)CC1 CHEMBL3729846 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCC(O)CC4)nc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730718 IC50 0.0 nM
CCN1CCN(c2ncc(-c3cccc([C@H](C)Nc4cc(-c5ccc6occ(C)c6c5)nc(C)n4)c3)cn2)CC1 CHEMBL3732789 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCC(O)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728037 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCC(O)C4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731016 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(NC(C)C)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3727718 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCC(CO)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3727394 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCC(F)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3729932 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(NCc4ccoc4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732537 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2cc(F)c3occ(C)c3c2)n1 CHEMBL3728422 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccc(CO)nc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730466 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc4c(c3)OCCN4C)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732121 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(CO)c3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3728795 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnn(C)c3)c2)cc(-c2cc(F)c3occ(C)c3c2)n1 CHEMBL3728831 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(CO)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730333 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(N)c3)c2)cc(-c2cc(F)c3occ(C)c3c2)n1 CHEMBL3728614 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(F)c3)c2)cc(-c2cc(F)c3occ(C)c3c2)n1 CHEMBL3727966 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2cc(F)c(Cl)c(F)c2)n1 CHEMBL3729017 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(Cl)c(N)c3)c2)cc(-c2cc(F)c3occ(C)c3c2)n1 CHEMBL3729329 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N)nc3)c2)cc(-c2ccc(F)c(F)c2)n1 CHEMBL3728078 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N)nc3)c2)cc(-c2cc(F)c(Cl)c(F)c2)n1 CHEMBL3732782 IC50 0.0 nM
CC(=O)c1cncc(-c2cccc([C@H](C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)c1 CHEMBL3731837 IC50 0.0 nM
Cc1nc(NC(C)c2cncc(-c3cn[nH]c3)c2)cc(-c2cc(F)c3occ(C)c3c2)n1 CHEMBL3729963 IC50 0.0 nM
CCn1cc(-c2cncc(C(C)Nc3cc(-c4cc(F)c5occ(C)c5c4)nc(C)n3)c2)cn1 CHEMBL3728767 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccc(F)nc3)c2)cc(-c2cc(F)c3occ(C)c3c2)n1 CHEMBL3732828 IC50 0.0 nM
CCOC(=O)c1cncc(-c2cccc([C@H](C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)c1 CHEMBL3730571 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(NCC(O)CO)nc3)c2)cc(-c2cc(F)c3occ(C)c3c2)n1 CHEMBL3727688 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCC(O)CC4)nc3)c2)cc(-c2cc(F)c3occ(C)c3c2)n1 CHEMBL3732548 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(C(C)O)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730220 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(C(C)(C)O)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3727576 IC50 0.0 nM
Cc1nc(NC(C)c2cncc(-c3cnn(C)c3)c2)cc(-c2cc(F)c3occ(C)c3c2)n1 CHEMBL3731873 IC50 0.0 nM
Cc1nc(NC(C)c2cncc(-c3cnc(N)nc3)c2)cc(-c2cc(F)c3occ(C)c3c2)n1 CHEMBL3729381 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N)nc3)c2)cc(-c2cc(F)c3occ(C)c3c2)n1 CHEMBL3728409 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccc(Cl)nc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3732478 IC50 0.0 nM
CCNc1ccc(-c2cccc([C@H](C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)cn1 CHEMBL3727653 IC50 0.0 nM
CCN1CCN(c2ccc(-c3cccc([C@H](C)Nc4cc(-c5ccc6occ(C)c6c5)nc(C)n4)c3)cn2)CC1 CHEMBL3731532 IC50 0.0 nM
CCN1CCN(c2ccc(-c3cccc([C@H](C)Nc4cc(-c5ccc6ncsc6c5)nc(C)n4)c3)cn2)CC1 CHEMBL3729999 IC50 0.0 nM
Cc1nc(NC(C)c2cncc(-c3cnc(N)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3727507 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccc(N4CCOCC4)nc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730398 IC50 0.0 nM
Cc1nc(N[C@H](C)c2cncc(-c3cnn(C)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728032 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccc(N4CCC(O)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3731195 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(Cl)c(C)c3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3730549 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(Cl)c(C)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730329 IC50 0.0 nM
Cc1nc(NC(C)c2cncc(Br)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730971 IC50 0.0 nM
Cc1nc(NC(C)c2cncc(-c3cncc(N)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732462 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N)nc3)c2)cc(-c2ccc(Cl)cc2)n1 CHEMBL3728659 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N)nc3)c2)cc(-c2ccc(Cl)c(F)c2)n1 CHEMBL3732722 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(N)c3)c2)cc(-c2ccc(Cl)c(F)c2)n1 CHEMBL3730569 IC50 0.0 nM
Cc1nc(NC(C)c2cncc(-c3cnc(N)nc3)c2)cc(-c2ccc(Cl)c(F)c2)n1 CHEMBL3731734 IC50 0.0 nM
Cc1nc(NC(C)c2cncc(-c3cnn(C)c3)c2)cc(-c2ccc(Cl)c(F)c2)n1 CHEMBL3730452 IC50 0.0 nM
CCn1cc(-c2cncc(C(C)Nc3cc(-c4ccc(Cl)c(F)c4)nc(C)n3)c2)cn1 CHEMBL3728497 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3ccc(N4CCNCC4)nc3)c2)cc(-c2ccc(Cl)c(F)c2)n1 CHEMBL3731364 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc(Cl)c(F)c2)n1 CHEMBL3729413 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(NCC(O)CO)nc3)c2)cc(-c2ccc(Cl)c(F)c2)n1 CHEMBL3728178 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCC(O)CC4)nc3)c2)cc(-c2ccc(Cl)c(F)c2)n1 CHEMBL3732306 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnccc3Cl)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3727523 IC50 0.0 nM
CCn1cc(-c2cccc([C@H](C)Nc3cc(-c4ccc(Cl)c(F)c4)nc(C)n3)c2)cn1 CHEMBL3733158 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(C(N)=O)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3730589 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2cccc(O)c2)n1 CHEMBL3730098 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3c(c2)CCO3)n1 CHEMBL3731527 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3ccc(F)nc3C)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3729912 IC50 0.0 nM
Cc1ccc(-c2cccc(C(C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)c(C)n1 CHEMBL3732607 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(NCCCN(C)C)nc3)c2)cc(-c2ccc3ncsc3c2)n1 CHEMBL3731212 IC50 0.0 nM
CC(=O)N1CCN(c2ncc(-c3cccc([C@H](C)Nc4cc(-c5ccc6occ(C)c6c5)nc(C)n4)c3)cn2)CC1 CHEMBL3729533 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc(Cl)c(N)c2)n1 CHEMBL3727780 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc(Cl)c(C)c2)n1 CHEMBL3732384 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc(C(N)=O)c(F)c2)n1 CHEMBL3733179 IC50 0.0 nM
Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3scnc3c2)n1 CHEMBL3727389 IC50 0.0 nM
CC(=O)N1CCN(c2ncc(-c3cccc([C@H](C)Nc4cc(-c5ccc6scc(C)c6c5)nc(C)n4)c3)cn2)CC1 CHEMBL3730762 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(N4CCN(CCN(C)C)CC4)nc3)c2)cc(-c2ccc3scc(C)c3c2)n1 CHEMBL3731623 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cncc(C#N)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3728296 IC50 0.0 nM
Cc1ccc(-c2cncc([C@H](C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)cn1 CHEMBL3730109 IC50 0.0 nM
Cc1nc(N[C@@H](C)c2cccc(-c3cnc(O)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 CHEMBL3732555 IC50 0.0 nM
CN1CCCC(NC(=O)c2ccncc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)C1 CHEMBL4541928 IC50 2.0 nM
Cc1noc(C)c1Cn1nc(C#N)c2cc(Oc3ccc(NC(=O)[C@@H]4CCCN4)cc3)ccc21 CHEMBL3422678 IC50 3.0 nM
COc1ccc([C@H](Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)c2cnnn2C)cn1 CHEMBL5079257 IC50 3.5 nM
COc1ccc(C(Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)c2cnnn2C)cn1 CHEMBL5078139 IC50 3.5 nM
CC(C)Cn1nc(C#N)c2cc(Oc3ccc(NC(=O)[C@@H]4CCCN4)cc3)ccc21 CHEMBL3422677 IC50 4.0 nM
Cc1csc2ccc(-c3cc(Nc4cnccc4C(=O)N[C@@H]4CCN(C)C4)cc4nccnc34)cc12 CHEMBL4592338 IC50 4.0 nM
Cn1cc([C@H](Nc2cc(-c3ccc4ocnc4c3)c3nccnc3c2)c2cnnn2C)cn1 CHEMBL5077027 IC50 4.2 nM
Cc1coc2ccc(-c3cc(N[C@@H](c4cnn(C)c4)c4cnnn4C)cc4nccnc34)cc12 CHEMBL5273875 IC50 4.2 nM
Cn1cc([C@H](Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)c2cnnn2C)cn1 CHEMBL5076616 IC50 5.2 nM
Cn1cc([C@H](Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)c2cccnc2)cn1 CHEMBL5078308 IC50 6.5 nM
CN1Cc2cc(-n3cc(C#N)c4cc(Oc5ccc(NC(=O)[C@@H]6CCCN6)cc5)ccc43)ccc2C1=O CHEMBL3422674 IC50 8.0 nM
COc1ccc([C@@H](Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)c2cccnc2)nn1 CHEMBL5076229 IC50 8.0 nM
Cc1csc2ccc(-c3cc(Nc4cnccc4C(=O)N[C@H]4CCN(C)C4)cc4nccnc34)cc12 CHEMBL4439789 IC50 9.0 nM
COc1ccc([C@@H](Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)c2cccnc2)cn1 CHEMBL5079598 IC50 9.9 nM
Cc1noc(C)c1Cn1cc(C#N)c2cc(Oc3ccc(NC(=O)[C@@H]4CCCN4)cc3)ccc21 CHEMBL3422676 IC50 11.0 nM
CC(=O)N1CCCC(NC(=O)c2ccncc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)C1 CHEMBL4465124 IC50 11.0 nM
CN1CCC(CNS(=O)(=O)c2ccccc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)C1 CHEMBL4449586 IC50 11.0 nM
Cn1cc([C@H](Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)c2cncn2C)cn1 CHEMBL5092801 IC50 14.0 nM
CN1CCC(NC(=O)c2ccncc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)C1 CHEMBL4471955 IC50 15.0 nM
CN1CCC(NC(=O)c2ccncc2Nc2cc(-c3cc(F)c4ccn(C)c4c3)c3nccnc3c2)C1 CHEMBL4542245 IC50 17.0 nM
CC(=O)N1CCC(NC(=O)c2ccncc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)CC1 CHEMBL4461874 IC50 18.0 nM
N#Cc1cn(Cc2ccccc2)c2ccc(Oc3ccc(NC(=O)[C@@H]4CCCN4)cc3)cc12 CHEMBL3422675 IC50 20.0 nM
Cn1cc(-c2cn(C)c3ccc(Oc4ccc(NC(=O)[C@@H]5CCCN5)cc4)cc23)cn1 CHEMBL3421731 IC50 21.0 nM
Cn1ccc2ccc(-c3cc(Nc4cnccc4C(=O)Nc4cncnc4)cc4nccnc34)cc21 CHEMBL4470835 IC50 22.0 nM
Cn1ccc2ccc(-c3cc(Nc4ccccc4S(=O)(=O)NCc4cncnc4)cc4nccnc34)cc21 CHEMBL4553861 IC50 22.0 nM
Cn1ccc([C@@H](Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)c2cnnn2C)n1 CHEMBL5093876 IC50 22.0 nM
CC(C)Cn1cc(C#N)c2cc(Oc3ccc(NC(=O)[C@@H]4CCCN4)cc3)ccc21 CHEMBL3422651 IC50 23.0 nM
Cn1cc([C@@H](Nc2cc(-c3ccc4ocnc4c3)c3nccnc3c2)c2cnnn2C)cn1 CHEMBL5083570 IC50 23.0 nM
Cn1ccc2ccc(-c3cc(Nc4ccccc4S(=O)(=O)NCC4CCOCC4)cc4nccnc34)cc21 CHEMBL4518022 IC50 26.0 nM
N#Cc1cn(-c2ccccc2)c2ccc(Oc3ccc(NC(=O)[C@@H]4CCCN4)cc3)cc12 CHEMBL3422673 IC50 27.0 nM
Cn1ccc2ccc(-c3cc(N[C@@H](c4cccnc4)c4ccc(=O)[nH]c4)cc4nccnc34)cc21 CHEMBL5084619 IC50 28.0 nM
Cc1c(S(=O)(=O)Nc2cccc(C(=O)O)c2)sc2ccc(C(C)C)cc12 CHEMBL3731843 IC50 30.0 nM
CN1CC(NC(=O)c2ccncc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)C1 CHEMBL4437856 IC50 30.0 nM
Cn1ccc2ccc(-c3cc(NC(c4cccnc4)c4ccc(=O)[nH]c4)cc4nccnc34)cc21 CHEMBL5081217 IC50 32.0 nM
Cn1ccc2ccc(-c3cc(Nc4cnccc4C(=O)NCC4COCCN4)cc4nccnc34)cc21 CHEMBL4459213 IC50 33.0 nM
Cn1cc(NC(=O)c2ccncc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)cn1 CHEMBL4465233 IC50 33.0 nM
CN1CCC(NS(=O)(=O)c2ccccc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)C1 CHEMBL4538989 IC50 33.0 nM
CC(C)[C@@H](Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1)c1cccnc1 CHEMBL5071836 IC50 33.0 nM
CN1CCC(NC(=O)c2ccncc2Nc2cc(-c3ccc4sc(N)nc4c3)c3nccnc3c2)C1 CHEMBL4438803 IC50 35.0 nM
CC(C)[C@H](Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1)c1cccnc1 CHEMBL5076430 IC50 35.0 nM
Cn1ccc2ccc(-c3cc(Nc4ccccc4S(=O)(=O)N4CCOCC4)cc4nccnc34)cc21 CHEMBL4576710 IC50 36.0 nM
Cn1ccc2ccc(-c3cc(Nc4cnccc4S(C)(=O)=O)cc4nccnc34)cc21 CHEMBL5272308 IC50 37.0 nM
CN1CCC(NC(=O)c2ccncc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)CC1 CHEMBL4472403 IC50 38.0 nM
Cn1cc(CNS(=O)(=O)c2ccccc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)cn1 CHEMBL4539068 IC50 38.0 nM
CN1CCC(NC(=O)c2ccncc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)CC1=O CHEMBL4442954 IC50 41.0 nM
Cn1cc([C@@H](Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)c2cncn2C)cn1 CHEMBL5093213 IC50 44.0 nM
Cn1ccc2ccc(-c3cc(Nc4cnccc4C(=O)NC4CCOCC4)cc4nccnc34)cc21 CHEMBL5286061 IC50 47.0 nM
N#Cc1cn(CC2CCOCC2)c2ccc(Oc3ccc(NC(=O)[C@@H]4CCCN4)cc3)cc12 CHEMBL3422672 IC50 48.0 nM
Cn1ccc2ccc(-c3cc(Nc4cnccc4C(N)=O)cc4nccnc34)cc21 CHEMBL4458729 IC50 49.0 nM
CN1CCCC(NS(=O)(=O)c2ccccc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)C1 CHEMBL4591819 IC50 59.0 nM
CN(Cc1cncnc1)S(=O)(=O)c1ccccc1Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1 CHEMBL4452425 IC50 62.0 nM
Cn1ccc2ccc(-c3cc(Nc4cnccc4C(=O)NC4CCNC(=O)C4)cc4nccnc34)cc21 CHEMBL4578329 IC50 69.0 nM
CC(=O)N1CC(NC(=O)c2ccncc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)C1 CHEMBL4448768 IC50 73.0 nM
CN1CCC(CNC(=O)c2ccncc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)C1 CHEMBL4439232 IC50 74.0 nM
CC(C)Cn1cc(C#N)c2cc(N(C)c3ccc(NC(=O)[C@@H]4CCCN4)cc3)ccc21 CHEMBL3421733 IC50 75.0 nM
Cc1c(S(=O)(=O)Nc2cccc(-c3nnn[nH]3)c2)oc2ccc(C(C)C)cc12 CHEMBL3731845 IC50 80.0 nM
CNC(=O)c1ccncc1Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1 CHEMBL4471750 IC50 83.0 nM
Cn1ccc2ccc(-c3cc(Nc4ccccc4S(C)(=O)=O)cc4nccnc34)cc21 CHEMBL4560682 IC50 85.0 nM
CCn1cc(C#N)c2cc(Oc3ccc(NC(=O)[C@@H]4CCN4)cc3)ccc21 CHEMBL3422667 IC50 86.0 nM
Cn1cc([C@@H](Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)c2cnnn2C)cn1 CHEMBL5078588 IC50 87.0 nM
O=C(OCCO)c1ccc(NS(=O)(=O)c2cccc(-c3cc(F)ccc3O)c2)cc1O CHEMBL5288625 IC50 90.0 nM
CC(=O)N1CCOC(CNC(=O)c2ccncc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)C1 CHEMBL4467929 IC50 93.0 nM
CN(C)S(=O)(=O)c1ccccc1Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1 CHEMBL4452310 IC50 94.0 nM
CCOC(=O)c1cc2ccc(O)cc2oc1=O CHEMBL155103 Ki 94.0 nM