COc1ncc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1NS(=O)(=O)c1cccnc1 CHEMBL3121323 pIC50 0.3162 nM
Nc1ncc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F CHEMBL3121314 pIC50 0.7943 nM
COc1ncc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1NS(=O)(=O)c1ccc(C#N)cc1 CHEMBL3121322 pIC50 1.0 nM
COc1ncc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1NS(=O)(=O)c1ccccc1C CHEMBL3121319 pIC50 1.0 nM
O=c1cc(-c2ccc3nc(NC[C@H]4CC[C@H](C(=O)O)CC4)sc3c2)ccn1CC1CC1 CHEMBL3600785 pIC50 1.0 nM
COc1ncc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F CHEMBL3121334 pIC50 1.585 nM
COc1ncc(-c2ccc3ncnc(N4CCOCC4)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F CHEMBL3121327 pIC50 1.585 nM
O=c1cc(-c2ccc3nc(NCC4CCS(=O)(=O)CC4)sc3c2)ccn1CC1CC1 CHEMBL3600784 pIC50 1.995 nM
COc1ncc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1NS(=O)(=O)c1ccccc1 CHEMBL3121318 pIC50 2.512 nM
COc1ncc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1NS(=O)(=O)c1cccc(C)c1 CHEMBL3121320 pIC50 3.981 nM
COc1ncc(-c2ccc3nc(N)n(-c4ccccc4C(F)(F)F)c(=O)c3c2)cc1S(=O)(=O)Nc1ccc(F)cc1F CHEMBL3121308 pIC50 5.012 nM
COc1ncc(-c2ccc3nc(N)c(-c4ccccc4)nc3c2)cc1NS(=O)(=O)c1ccc(F)cc1F CHEMBL3121333 pIC50 5.012 nM
O=c1cc(-c2ccc3nc(NCC4CCOCC4)sc3c2)ccn1CC1CC1 CHEMBL3600781 pIC50 5.012 nM
COc1ncc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1S(=O)(=O)Nc1ccc(F)cc1F CHEMBL3121324 pIC50 6.31 nM
Nc1nc2ccc(-c3ccn(CC4CC4)c(=O)c3)cc2s1 CHEMBL3600779 pIC50 6.31 nM
C[C@@H](Nc1nc2ccc(-c3ccn(CC4CC4)c(=O)c3)cc2s1)C1CCOCC1 CHEMBL3600782 pIC50 7.943 nM
COc1ncc(-c2ccc3nc(N)n(-c4ccccc4C)c(=O)c3c2)cc1S(=O)(=O)Nc1ccc(F)cc1F CHEMBL3121311 pIC50 10.0 nM
COc1ncc(-c2ccc3nc(N)n(C4CCOCC4)c(=O)c3c2)cc1S(=O)(=O)Nc1ccc(F)cc1F CHEMBL3121326 pIC50 10.0 nM
COc1ncc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1NS(=O)(=O)c1ccc(C)cc1 CHEMBL3121321 pIC50 15.85 nM
COc1ncc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1NS(C)(=O)=O CHEMBL3121316 pIC50 19.95 nM
COc1ncc(-c2ccc3nc(N)n(-c4ccccc4C(C)C)c(=O)c3c2)cc1S(=O)(=O)Nc1ccc(F)cc1F CHEMBL3121312 pIC50 31.62 nM
CCn1c(N)nc2ccc(-c3cnc(OC)c(S(=O)(=O)Nc4ccc(F)cc4F)c3)cc2c1=O CHEMBL3121325 pIC50 39.81 nM
COc1ncc(-c2ccc3nc(N)c(-c4ccc(N5CCOCC5)cc4)cc3c2)cc1NS(=O)(=O)c1ccc(F)cc1F CHEMBL3121328 pIC50 39.81 nM
C[C@H](Nc1nc2ccc(-c3ccn(CC4CC4)c(=O)c3)cc2s1)C1CCOCC1 CHEMBL3600783 pIC50 39.81 nM
COc1ncc(-c2ccc3nc(N)n(-c4ccc(C(F)(F)F)cc4)c(=O)c3c2)cc1S(=O)(=O)Nc1ccc(F)cc1F CHEMBL3121310 pIC50 50.12 nM
COc1ncc(-c2ccc3nc(N)n(-c4cccc(C(F)(F)F)c4)c(=O)c3c2)cc1S(=O)(=O)Nc1ccc(F)cc1F CHEMBL3121309 pIC50 50.12 nM
CC(C)Oc1ccc(-c2ccc3nc(N)sc3c2)cn1 CHEMBL3600687 pIC50 79.43 nM
COc1ncc(-c2ccc3nc(N)c(-c4ccccc4)cc3c2)cc1NS(=O)(=O)c1ccc(F)cc1F CHEMBL3121329 pIC50 100.0 nM
CCSc1ccc(-c2ccc3nc(N)sc3c2)cn1 CHEMBL3600684 pIC50 100.0 nM
COc1ncc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1NS(=O)(=O)C(C)C CHEMBL3121317 pIC50 125.89 nM
Cc1ccccc1S(=O)(=O)Nc1cc(-c2sc(NC(=O)[C@@H](N)C(C)C)nc2C)cnc1Cl CHEMBL4161766 IC50 130.6 nM
Nc1nc2ccc(-c3cnn(Cc4ccccc4)c3)cc2s1 CHEMBL3600776 pIC50 158.49 nM
CCOc1ccc(-c2ccc3nc(N)sc3c2)cn1 CHEMBL3600683 pIC50 158.49 nM
Cc1ccc(S(=O)(=O)Nc2cc(-c3sc(NC(=O)[C@@H](N)C(C)C)nc3C)cnc2Cl)cc1 CHEMBL4164334 IC50 163.7 nM
CNC(=O)c1cncc(-c2cnc(Cl)c(NS(=O)(=O)c3ccccc3)c2)c1 CHEMBL4752128 IC50 165.0 nM
COc1ncc(-c2cc3cc(-c4ccccc4)c(N)nc3cn2)cc1NS(=O)(=O)c1ccc(F)cc1F CHEMBL3121331 pIC50 199.53 nM
COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O CHEMBL428496 IC50 280.0 nM
COc1ccc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F CHEMBL3121313 pIC50 316.23 nM
CCn1ccc(-c2ccc3nc(N)sc3c2)cc1=O CHEMBL3600778 pIC50 316.23 nM
Nc1nc2ccc(-c3cc[nH]c(=O)c3)cc2s1 CHEMBL3600767 pIC50 316.23 nM
COCCOc1ccc(-c2ccc3nc(N)sc3c2)cn1 CHEMBL3600695 pIC50 316.23 nM
Nc1nc2ccc(-c3ccc(OCCO)nc3)cc2s1 CHEMBL3600694 pIC50 316.23 nM
CS(=O)(=O)c1cncc(-c2ccc3nc(N)sc3c2)c1 CHEMBL3600699 pIC50 398.11 nM
CC(C)(C)OC(=O)CCNC(=O)Nc1nc2c(s1)-c1nc(-c3ccccc3Cl)ncc1CC2 CHEMBL3901551 IC50 450.0 nM
Cn1ccc(-c2ccc3nc(N)sc3c2)cc1=O CHEMBL3600777 pIC50 501.19 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)NC5CCC(N)CC5)c4)c(C)nc23)ccn1 CHEMBL3947384 IC50 553.0 nM
Cc1cccc(S(=O)(=O)Nc2cc(-c3sc(NC(=O)[C@@H](N)C(C)C)nc3C)cnc2Cl)c1 CHEMBL4174988 IC50 574.1 nM
COc1ncc(-c2cnc3nc(N)c(-c4ccccc4)cc3c2)cc1NS(=O)(=O)c1ccc(F)cc1F CHEMBL3121330 pIC50 630.96 nM
COCCOn1ccc(-c2ccc3nc(N)sc3c2)cc1=O CHEMBL3600780 pIC50 630.96 nM
Nc1nc2ccc(-c3cnn(CC4CC4)c3)cc2s1 CHEMBL3600775 pIC50 630.96 nM
CCN(C)c1ccc(-c2ccc3nc(N)sc3c2)cn1 CHEMBL3600689 pIC50 630.96 nM
CCNc1ccc(-c2ccc3nc(N)sc3c2)cn1 CHEMBL3600688 pIC50 630.96 nM
COc1ccc(-c2ccc3nc(N)sc3c2)cn1 CHEMBL1645105 pIC50 630.96 nM
COc1ccc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)cc1S(=O)(=O)NC1CCC(N)CC1 CHEMBL3986552 IC50 660.0 nM
CC(C)Oc1cncc(-c2ccc3nc(N)sc3c2)c1 CHEMBL3600698 pIC50 1000.0 nM
COCc1ccc(-c2ccc3nc(N)sc3c2)cn1 CHEMBL3600685 pIC50 1000.0 nM