COc1ccc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)cc1S(=O)(=O)N1CCOCC1 CHEMBL3923414 IC50 0.98 nM
COc1ccc(NC(=O)N2CCN(c3nc(N)nc4sc(-c5cccnc5)nc34)CC2)cc1 CHEMBL4205416 IC50 2.0 nM
COc1ccc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)cc1S(=O)(=O)N(C)C CHEMBL3930509 IC50 2.4 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)NCc5cn(Cc6ccccc6)nn5)c4)c(C)nc23)ccn1 CHEMBL3936684 Kd 3.7 nM
COc1ccc(NC(=O)N2CCN(c3nc(N)nc4scnc34)[C@@H](C)C2)c(C)c1 CHEMBL4215340 IC50 4.0 nM
CNC(=O)c1cc(-c2ccnc(C(=O)NCc3cccc(-n4cccn4)c3)c2)ccc1Cl CHEMBL4211696 IC50 4.0 nM
Cc1ccc(NC(=O)N2CCN(c3nc(N)nc4sc(-c5cccnc5)nc34)CC2)cc1 CHEMBL4206816 IC50 5.0 nM
COc1ccc(NC(=O)N2CCN(c3nc(N)nc4c3cnn4C)[C@@H](C)C2)c(C)c1 CHEMBL4211181 IC50 5.0 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)NC(CC)CO)c4)c(C)nc23)ccn1 CHEMBL3958915 IC50 5.3 nM
Cc1nc2c(NCc3cccc(S(C)(=O)=O)c3)nccn2c1-c1ccc(O)c(F)c1 CHEMBL2407818 IC50 5.7 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)NCCO)c4)c(C)nc23)ccn1 CHEMBL3976651 IC50 6.1 nM
C#CCNS(=O)(=O)c1cc(-c2c(C)nc3c(NCc4ccnc(CC)c4)cc(Cl)nn23)ccc1OC CHEMBL3974986 Kd 6.1 nM
CCNS(=O)(=O)c1cc(-c2c(C)nc3c(NCc4ccnc(CC)c4)cc(Cl)nn23)ccc1OO CHEMBL5188324 IC50 6.1 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)N5CCC(O)CC5)c4)c(C)nc23)ccn1 CHEMBL3920652 IC50 6.2 nM
COc1ccc(NC(=O)N2CCN(c3nc(N)nc4sccc34)[C@@H](C)C2)c(C)c1 CHEMBL4215244 IC50 7.0 nM
COc1ccc(NC(=O)N2CCN(c3nc(N)nc4sncc34)[C@@H](C)C2)c(C)c1 CHEMBL4203566 IC50 7.0 nM
CCC(CO)NS(=O)(=O)c1cc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)ccc1OC CHEMBL3911522 IC50 7.23 nM
CC(C)n1nc(-c2ccc3ncccc3c2)c2c(N)ncnc21 CHEMBL1233882 IC50 8.0 nM
COc1ccc(NC(=O)N2CCN(c3nc(N)nc4scnc34)[C@@H](C)C2)cc1 CHEMBL4203041 IC50 8.0 nM
Cc1cc(CNc2cc(C)nc3c(-c4ccc(Cl)c(NS(C)(=O)=O)c4)c(C)nn23)ccn1 CHEMBL4202450 IC50 8.0 nM
COc1ccc(NC(=O)N2CCN(c3nc(N)nc4c3ncn4C)[C@@H](C)C2)c(C)c1 CHEMBL4209793 IC50 8.0 nM
COc1ccc(-c2c(C)nn3c(NCCN4CCOCC4)cc(C)nc23)cc1OC CHEMBL2397317 IC50 8.0 nM
C=CCNS(=O)(=O)c1cc(-c2c(C)nc3c(NCc4ccnc(CC)c4)cc(Cl)nn23)ccc1OC CHEMBL3939697 IC50 8.6 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)NCCN(C)C)c4)c(C)nc23)ccn1 CHEMBL3957128 IC50 9.0 nM
COc1ccc(NC(=O)N2CCN(c3nc(N)nc4scnc34)CC2)c(C)c1 CHEMBL4207851 IC50 9.0 nM
Nc1nc(N2CCN(C(=O)COc3ccc(Cl)cc3)CC2)c2nc(-c3cccnc3)sc2n1 CHEMBL1652677 IC50 10.0 nM
Cc1cc([C@@H](C)Nc2ccccc2C(=O)O)c2nc(N3CCOCC3)cc(=O)n2c1 CHEMBL2165191 IC50 10.0 nM
COc1ccc(NC(=O)N2CCN(c3nc(N)nc4sc(-c5ccccc5)nc34)CC2)cc1 CHEMBL4210308 IC50 11.0 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4cccc(S(=O)(=O)N(C)C)c4)c(C)nc23)ccn1 CHEMBL3959713 IC50 12.5 nM
COc1ccc(-c2sc(NC(=O)Cc3ccccc3)nc2C)cc1S(=O)(=O)Nc1ccccc1 CHEMBL5431632 IC50 14.0 nM
COc1ccc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)cc1S(=O)(=O)N1CCC(CO)CC1 CHEMBL3902513 IC50 14.9 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)NC5CCC(N)CC5)c4)c(C)nc23)ccn1 CHEMBL3947384 IC50 15.7 nM
CCN(CC)S(=O)(=O)c1cc(-c2sc(NC(=O)Cc3cc(OC)cc(OC)c3)nc2C)ccc1OC CHEMBL5435139 IC50 16.0 nM
COc1ccc(-c2sc(NC(=O)Cc3ccccc3)nc2C)cc1NS(=O)(=O)c1cccnc1 CHEMBL5403406 IC50 16.0 nM
COc1cc(CC(=O)Nc2nc(C)c(-c3ccc(OC)c(NS(=O)(=O)c4ccccc4)c3)s2)cc(OC)c1 CHEMBL5432195 IC50 16.0 nM
CC(C)n1nc(-c2ccc(Br)c(O)c2)c2c(N)ncnc21 CHEMBL1241578 IC50 17.0 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)NCCOC)c4)c(C)nc23)ccn1 CHEMBL3929556 IC50 17.2 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)N5CCOCC5)c4)c(C)nc23)ccn1 CHEMBL3894217 IC50 17.6 nM
COc1ccc(NC(=O)N2CCN(c3nc(N)nc4scnc34)C(C)C2)cc1 CHEMBL4204100 IC50 18.0 nM
Nc1ccc(-c2ccc3ncc4ccc(=O)n(-c5cccc(C(F)(F)F)c5)c4c3c2)cn1 CHEMBL1765602 IC50 18.3 nM
CC(=O)/N=c1/[nH]c(C)c(-c2ccc(Cl)c(S(=O)(=O)NCCO)c2)s1 CHEMBL1229535 IC50 19.0 nM
CCN(CC)S(=O)(=O)c1cc(-c2sc(NC(=O)Cc3ccccc3)nc2C)ccc1OC CHEMBL5439775 IC50 19.0 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)n5cccn5)c4)c(C)nc23)ccn1 CHEMBL3948449 IC50 19.1 nM
C=CCNS(=O)(=O)c1cc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)ccc1OC CHEMBL3893537 IC50 19.9 nM
Cc1nc2sc1-c1cc3c(c(c1)S(=O)(=O)NCCOCCNC(=O)c1cccc(n1)N2)C(=O)N([C@@H](C)C1CC1)C3 CHEMBL5091438 pIC50 19.95 nM
COc1ccc(NC(=O)N2CCN(c3nc(N)nc4scnc34)[C@@H](C)C2)c(C)n1 CHEMBL4207928 IC50 20.0 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)NCc5cn(-c6cc7ccc(O)cc7oc6=O)nn5)c4)c(C)nc23)ccn1 CHEMBL3963020 Kd 21.0 nM
CCN(CC)S(=O)(=O)c1cc(-c2sc(NC(=O)Cc3cccc(C)c3)nc2C)ccc1OC CHEMBL5431408 IC50 21.0 nM
CO[C@H]1CC[C@@H](C(=O)Nc2nc(C)c(-c3ccc(N)nc3)s2)CC1 CHEMBL2397309 IC50 22.0 nM
COc1ccc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)cc1S(=O)(=O)NCCO CHEMBL3889874 IC50 22.0 nM
CCN(CC)S(=O)(=O)c1cc(-c2sc(NC(=O)Cc3cccc(OC)c3)nc2C)ccc1OC CHEMBL5402886 IC50 26.0 nM
Cc1nc2c(NCc3ccncc3)cc(Cl)nn2c1-c1cccc(S(=O)(=O)N(C)C)c1 CHEMBL3915835 IC50 26.4 nM
COc1ccc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)cc1S(=O)(=O)NC1CCC(N)CC1 CHEMBL3986552 IC50 26.9 nM
COc1ccc(-c2sc(NC(=O)Cc3ccccc3)nc2C)cc1NS(=O)(=O)c1ccccc1 CHEMBL5427380 IC50 27.0 nM
COc1ccc(-c2sc(NC(=O)Cc3ccccc3)nc2C)cc1NS(=O)(=O)c1ccc(F)cc1 CHEMBL5425138 IC50 27.0 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)N(C)C)c4)c(C)nc23)ccn1 CHEMBL3925101 IC50 27.3 nM
CCN(CC)S(=O)(=O)c1cc(-c2sc(NC(=O)Cc3cccc(F)c3)nc2C)ccc1OC CHEMBL5395492 IC50 29.0 nM
CCN(CC)S(=O)(=O)c1cc(-c2sc(NC(=O)CCc3ccccc3)nc2C)ccc1OC CHEMBL5401566 IC50 30.0 nM
Cc1cc(CNc2cc(Cl)nn3c(-c4cccc(S(=O)(=O)N(C)C)c4)c(C)nc23)ccn1 CHEMBL3905730 IC50 33.7 nM
Cc1nc(NC(=O)C(C)CC(F)(F)F)sc1-c1ccc(N)nc1 CHEMBL2397312 IC50 35.0 nM
CO[C@H]1CC[C@H](N2C(=O)CNc3ncc(-c4ccc(C(C)(C)O)nc4)nc32)CC1 CHEMBL3586404 Kd 39.0 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)NCc5cn(CCCNC(=O)c6ccc7c(c6)C6(OC7=O)c7ccc(O)cc7Oc7cc(O)ccc76)nn5)c4)c(C)nc23)ccn1 CHEMBL3966476 IC50 39.4 nM
Cc1cc(NC(=O)CCNC(=O)Nc2nc(C)c(-c3ccc(-n4cccn4)cc3)s2)no1 CHEMBL1986603 IC50 40.0 nM
Cc1nc(NC(=O)C2(C)CCCCC2)sc1-c1ccc(N)nc1 CHEMBL2397311 IC50 40.0 nM
CCN(CC)S(=O)(=O)c1cc(-c2sc(NC(=O)Cc3cccc(Cl)c3)nc2C)ccc1OC CHEMBL5410515 IC50 40.0 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)N5CCC(CO)CC5)c4)c(C)nc23)ccn1 CHEMBL3969997 IC50 41.5 nM
Cc1nc(NC(=O)[C@@H](C)c2ccc(Cl)cc2)[nH]c1-c1ccc(Cl)c(S(=O)(=O)NCCO)c1 CHEMBL4215615 IC50 42.0 nM
COc1ccc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)cc1S(=O)(=O)N1CCC(O)CC1 CHEMBL3921556 IC50 43.8 nM
Cc1nc(NC(=O)C(C)(C)CC(F)(F)F)sc1-c1ccc(N)nc1 CHEMBL2397316 IC50 48.0 nM
COc1ccc(NC(=O)N2CCN(c3nc(N)nc4scnc34)CC2)cc1 CHEMBL4217096 IC50 51.0 nM
Cc1nc(NC(=O)[C@@H](C)CC(F)(F)F)sc1-c1ccc(N)nc1 CHEMBL2397315 IC50 53.0 nM
Cc1nc(NC(=O)[C@H]2CC[C@@H](C(F)(F)F)CC2)sc1-c1ccc(N)nc1 CHEMBL2397310 IC50 53.0 nM
CC(=O)NCCNc1cc(Cl)nn2c(-c3cccc(S(=O)(=O)N(C)C)c3)c(C)nc12 CHEMBL3914714 IC50 54.0 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)NC5CC5)c4)c(C)nc23)ccn1 CHEMBL3898792 IC50 56.0 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)N5CCCCC5)c4)c(C)nc23)ccn1 CHEMBL3938589 IC50 59.2 nM
Nc1ncnc2c1c(-c1cnc3[nH]ccc3c1)nn2C1CCCC1 CHEMBL1081312 IC50 60.0 nM
CCN(CC)S(=O)(=O)c1cc(-c2sc(NC(=O)Cc3ccccc3OC)nc2C)ccc1OC CHEMBL5423836 IC50 60.0 nM
CC(C)S(=O)(=O)n1c(N)nc2ccc(/C(=N/O)c3ccccc3)cc21 CHEMBL283403 IC50 64.0 nM
CC(C)(C)c1ncc2c(n1)-c1sc(NC(=O)N3CCC[C@@]3(C)C(N)=O)nc1CC2 CHEMBL3609523 IC50 65.0 nM
CCN(CC)S(=O)(=O)c1cc(-c2sc(NC(=O)Cc3cc(OC)c(OC)c(OC)c3)nc2C)ccc1OC CHEMBL5415642 IC50 66.0 nM
Cc1nc(NC(=O)Cc2nc(-c3ccccc3)c(C)o2)sc1-c1ccc(N)nc1 CHEMBL2397313 IC50 67.0 nM
Cc1ccc(S(=O)(=O)Nc2cc(-c3sc(NC(=O)[C@@H](N)C(C)C)nc3C)cnc2Cl)cc1 CHEMBL4164334 IC50 68.0 nM
COc1ccc(-c2c(C)nc3c(NCCNC(C)=O)cc(C)nn23)cc1OC CHEMBL4646734 IC50 70.0 nM
CCN(CC)S(=O)(=O)c1cc(-c2sc(NC(=O)Cc3ccc(OC)c(OC)c3)nc2C)ccc1OC CHEMBL5431413 IC50 72.0 nM
Cc1nc2c(NCc3cccnc3)cc(Cl)nn2c1-c1cccc(S(=O)(=O)N(C)C)c1 CHEMBL3933495 IC50 74.6 nM
Cc1ccc(NC(=O)N2CCN(c3nc(N)nc4scnc34)CC2)cc1 CHEMBL4205444 IC50 85.0 nM
Cc1cc(N2C[C@H]3CC[C@@H](C2)[C@@H]3Nc2nc3c(O[C@@H](C)C(F)(F)F)cccn3n2)sn1 CHEMBL4637839 Kd 85.0 nM
Cc1nc(NC(=O)C(C)(C)C)sc1-c1csc(Nc2cccc(C(=O)O)c2)n1 CHEMBL4471507 IC50 90.0 nM
COc1ccc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)cc1S(=O)(=O)NCCN(C)C CHEMBL3965171 IC50 93.5 nM
CCN(CC)S(=O)(=O)c1cc(-c2sc(NC(=O)C(C)(C)C)nc2C)ccc1OC CHEMBL5396829 IC50 94.0 nM
COc1ccc(-c2nn(C3CCC3)c3ncnc(N)c23)cc1OC CHEMBL1233881 IC50 99.0 nM
Nc1ccc(-c2cnc(NC(=O)CN(Cc3ccccc3)C(=O)c3ccncc3)s2)cc1 CHEMBL2397303 IC50 100.0 nM
COc1ccc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)cc1S(=O)(=O)NC1CC1 CHEMBL3939491 IC50 105.8 nM
Cc1ccccc1NC(=O)N1CCN(c2nc(N)nc3scnc23)CC1 CHEMBL4209824 IC50 114.0 nM
Cc1ccccc1S(=O)(=O)Nc1cc(-c2sc(NC(=O)[C@@H](N)C(C)C)nc2C)cnc1Cl CHEMBL4161766 IC50 114.5 nM
Cc1cccc(NC(=O)N2CCN(c3nc(N)nc4scnc34)CC2)c1 CHEMBL4210332 IC50 115.0 nM
Cc1nsc(N2CC3CCC(C2)C3Nc2nc3c(-c4ccc(F)c(F)c4F)cccn3n2)n1 CHEMBL4649825 Kd 120.0 nM
Cc1cc(N2C[C@H]3CC[C@@H](C2)[C@@H]3Nc2nc3c(OCC(F)(F)F)cccn3n2)sn1 CHEMBL4635478 Kd 120.0 nM
COCCNS(=O)(=O)c1cc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)ccc1OC CHEMBL3932492 IC50 134.8 nM
C=CC(=O)Nc1nc(-c2sc(NC(C)=O)nc2C)cs1 CHEMBL4461468 IC50 140.0 nM
Cc1nc2c(NCc3ccccn3)cc(Cl)nn2c1-c1cccc(S(=O)(=O)N(C)C)c1 CHEMBL3924835 IC50 145.4 nM
CNCCNS(=O)(=O)c1cc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)ccc1OC CHEMBL3948269 IC50 146.9 nM
Cc1nsc(N2C[C@H]3CC[C@@H](C2)[C@@H]3Nc2nc3c(OCC(F)(F)F)cccn3n2)n1 CHEMBL4639184 Kd 150.0 nM
C[C@@H]1CCN(C(=O)Nc2nc3c(s2)-c2nc(C(C)(C)C)ncc2CC3)[C@@H]1C(N)=O CHEMBL3609525 IC50 160.0 nM
CCN(CC)S(=O)(=O)c1cc(-c2sc(NC(=O)Cc3ccccc3Cl)nc2C)ccc1OC CHEMBL5428790 IC50 160.0 nM
CCN(CC)S(=O)(=O)c1cc(-c2sc(NC(=O)Cc3ccc(Cl)cc3)nc2C)ccc1OC CHEMBL5411938 IC50 160.0 nM
CCN(CC)S(=O)(=O)c1cc(-c2sc(NC(=O)Cc3ccc(OC)cc3)nc2C)ccc1OC CHEMBL5428664 IC50 160.0 nM
COc1ccc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)cc1S(=O)(=O)n1cccn1 CHEMBL3959992 IC50 163.3 nM
COc1ccc(NC(=O)N2CCN(c3nc(N)nc4scnc34)CC2)c(C)n1 CHEMBL4216301 IC50 173.0 nM
COc1ccc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)cc1S(=O)(=O)N1CCCCC1 CHEMBL3978329 IC50 189.4 nM
CCN(CC)S(=O)(=O)c1cc(-c2sc(NC(=O)Cc3ccc(C)cc3)nc2C)ccc1OC CHEMBL5435605 IC50 190.0 nM
CC(C)n1nc(-c2ccc(O)c(F)c2)c2c(N)ncnc21 CHEMBL1241945 IC50 210.0 nM
C[C@@H]1CCN(C(=O)Nc2nc3c(s2)-c2nc(C(C)(C)C)sc2CC3)[C@@H]1C(N)=O CHEMBL3609519 IC50 210.0 nM
Nc1nc(N2CCN(C(=O)COc3ccc(Cl)cc3)CC2)c2ncsc2n1 CHEMBL4210718 IC50 216.0 nM
Cc1nc(NC(=O)[C@H](C)CC(F)(F)F)sc1-c1ccc(N)nc1 CHEMBL2397314 IC50 225.0 nM
CC(=O)c1ccc(-c2sc(NC(=O)NCCC(=O)NC(C)(C)C)nc2C)cc1 CHEMBL2069328 IC50 240.0 nM
Cc1nc(NC(=O)N2CC[C@@H](C)[C@H]2C(N)=O)sc1-c1csc(C2(C(F)(F)F)CC2)n1 CHEMBL3608927 IC50 250.0 nM
FC(F)(F)COc1cccn2nc(N[C@@H]3[C@@H]4CC[C@H]3CN(c3ccnc(C(F)(F)F)c3)C4)nc12 CHEMBL4638937 Kd 250.0 nM
O=c1cc(-c2ccc3nc(NC[C@H]4CC[C@H](C(=O)O)CC4)sc3c2)ccn1CC1CC1 CHEMBL3600785 pIC50 251.19 nM
COc1c(Cl)cc2c([nH]c3cnccc32)c1NC(=O)c1cccnc1C CHEMBL608154 Kd 270.0 nM
COc1ccc(NC(=O)N2C[C@H](C)N(c3nc(N)nc4scnc34)C[C@H]2C)cc1 CHEMBL4213363 IC50 275.0 nM
C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O CHEMBL603469 Kd 290.0 nM
Cc1cccc(S(=O)(=O)Nc2cc(-c3sc(NC(=O)[C@@H](N)C(C)C)nc3C)cnc2Cl)c1 CHEMBL4174988 IC50 300.2 nM
COc1ccc(NC(=O)N2CCN(c3nc(N)nc4scnc34)[C@H](C)C2)c(C)c1 CHEMBL4203671 IC50 316.0 nM
COCc1ccc(-c2ccc3nc(N)sc3c2)cn1 CHEMBL3600685 pIC50 316.23 nM
Cn1ccc(-c2ccc3nc(N)sc3c2)cc1=O CHEMBL3600777 pIC50 316.23 nM
CCn1ccc(-c2ccc3nc(N)sc3c2)cc1=O CHEMBL3600778 pIC50 316.23 nM
C[C@@H](Nc1nc2ccc(-c3ccn(CC4CC4)c(=O)c3)cc2s1)C1CCOCC1 CHEMBL3600782 pIC50 316.23 nM
CC(C)(C)c1nc2c(s1)CCc1nc(NC(=O)N3CCC[C@H]3C(N)=O)sc1-2 CHEMBL3609514 IC50 320.0 nM
Nc1nc(N2CCN(C(=O)Nc3ccc(OC(F)(F)F)cc3)CC2)c2ncsc2n1 CHEMBL4214728 IC50 331.0 nM
Nc1nc2c(-c3cnc4ccccc4c3)nccc2[nH]1 CHEMBL2153266 Kd 350.0 nM
Nc1nc(N2CCN(C(=O)Nc3ccccc3)CC2)c2ncsc2n1 CHEMBL4206897 IC50 380.0 nM
O=c1cc(-c2ccc3nc(NCC4CCOCC4)sc3c2)ccn1CC1CC1 CHEMBL3600781 pIC50 398.11 nM
CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 CHEMBL1241674 IC50 408.0 nM
COc1cc(C)c(NC(=O)N2CCN(c3nc(N)nc4scnc34)CC2)cn1 CHEMBL4202963 IC50 414.0 nM
COc1ccc(NC(=O)N2CCN(c3nc(N)nc4scnc34)CC2)cn1 CHEMBL4202542 IC50 424.0 nM
c1nc(NCC2CCOC2)c2cc(-c3ccc4c(c3)OCO4)ccc2n1 CHEMBL1436585 Kd 430.0 nM
Nc1nc(N)c2nc(-c3cccc(O)c3)c(-c3cccc(O)c3)nc2n1 CHEMBL230011 Kd 430.0 nM
CNC(=O)c1cncc(-c2cnc(Cl)c(NS(=O)(=O)c3ccccc3)c2)c1 CHEMBL4752128 IC50 433.0 nM
COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O CHEMBL428496 IC50 440.0 nM
CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)cc4)c(C)nc23)ccn1 CHEMBL3942710 IC50 444.1 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 Kd 460.0 nM
CC(C)n1nc(-c2cc(F)c(O)cc2F)c2c(N)ncnc21 CHEMBL1242028 IC50 470.0 nM
Nc1nc2ccc(-c3ccccc3)cc2s1 CHEMBL97245 pIC50 501.19 nM
Nc1nc2ccc(-c3ccc(OCCO)nc3)cc2s1 CHEMBL3600694 pIC50 501.19 nM
Cc1ccc(-c2ccc3nc(N)sc3c2)cn1 CHEMBL3600691 pIC50 501.19 nM
Cc1nc(Nc2cccc(N3CCOCC3=O)n2)sc1-c1cc2c(c(S(=O)(=O)NC3COC3)c1)C(=O)N([C@@H](C)C1CC1)C2 CHEMBL5077865 pIC50 501.19 nM
COc1ccc(-c2sc(NC(=O)Cc3ccccc3)nc2C)cc1NS(=O)(=O)c1cccc(F)c1 CHEMBL5426813 IC50 510.0 nM
COc1cc(-c2nn(C3CCCC3)c3ncnc(N)c23)ccc1N CHEMBL1241581 IC50 530.0 nM
COc1ccc(NC(=O)N2C[C@@H](C)N(c3nc(N)nc4scnc34)[C@@H](C)C2)cc1 CHEMBL4208440 IC50 543.0 nM
CC(=O)Nc1nc(C)c(-c2csc(N(CCO)c3cccc(C(C)=O)c3)n2)s1 CHEMBL4531023 IC50 600.0 nM
CCSc1ccc(-c2ccc3nc(N)sc3c2)cn1 CHEMBL3600684 pIC50 630.96 nM
CCOc1ccc(-c2ccc3nc(N)sc3c2)cn1 CHEMBL3600683 pIC50 630.96 nM
Nc1nc2ccc(-c3cccnc3)cc2s1 CHEMBL3600701 pIC50 630.96 nM
Nc1nc2ccc(-c3cc[nH]c(=O)c3)cc2s1 CHEMBL3600767 pIC50 630.96 nM
O=c1cc(-c2ccc3nc(NCC4CCS(=O)(=O)CC4)sc3c2)ccn1CC1CC1 CHEMBL3600784 pIC50 630.96 nM
COc1ccc(NC(=O)N2CC3CCC(C2)N3c2nc(N)nc3scnc23)cc1 CHEMBL4212822 IC50 635.0 nM
Cc1nc(NC(=O)C(C)(C)C)sc1-c1csc(NCCO)n1 CHEMBL4580215 IC50 730.0 nM
Cc1c(Nc2nc(N)c3c(C#N)c(N4CCC[C@H]4C)n(C)c3n2)cnn1[C@H]1CCOC1 CHEMBL5092087 Kd 730.0 nM
COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL509032 Kd 780.0 nM
Nc1nc2ccc(-c3ccc(CO)nc3)cc2s1 CHEMBL3600690 pIC50 794.33 nM
Nc1nc2ccc(-c3cnn(Cc4ccccc4)c3)cc2s1 CHEMBL3600776 pIC50 794.33 nM
Cc1c(Nc2nc(N)c3c(C#N)c(N4CCC[C@H]4C)n(C)c3n2)cnn1[C@@H]1CCOC1 CHEMBL5087055 Kd 850.0 nM
COc1cc(-c2nn(C(C)C)c3ncnc(N)c23)ccc1O CHEMBL1242112 IC50 870.0 nM
Cc1nc(NC(=O)N2CCC[C@H]2C(N)=O)sc1-c1ccc(-n2cccn2)cc1 CHEMBL2071338 IC50 920.0 nM
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC CHEMBL475251 Kd 930.0 nM
CS(=O)(=O)CCNCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)o1 CHEMBL554 Kd 940.0 nM
Nc1nc(N2CCN(C(=O)c3cn4ccccc4n3)CC2)c2ncsc2n1 CHEMBL4205943 IC50 946.0 nM
Cc1ccc(Nc2nccc(N(C)c3ccc4c(C)n(C)nc4c3)n2)cc1S(N)(=O)=O CHEMBL477772 Kd 960.0 nM
CC(C)Oc1cncc(-c2ccc3nc(N)sc3c2)c1 CHEMBL3600698 pIC50 1000.0 nM
COCCOc1ccc(-c2ccc3nc(N)sc3c2)cn1 CHEMBL3600695 pIC50 1000.0 nM
CCNc1ccc(-c2ccc3nc(N)sc3c2)cn1 CHEMBL3600688 pIC50 1000.0 nM
COc1ccc(-c2ccc3nc(N)sc3c2)cn1 CHEMBL1645105 pIC50 1000.0 nM
Nc1nc2ccc(-c3ccncc3)cc2s1 CHEMBL1645107 pIC50 1000.0 nM
Cn1nccc1-c1ccc2nc(N)sc2c1 CHEMBL3600769 pIC50 1000.0 nM
COc1ccc(NC(=O)N2CCN(c3nc(N)nc4c3cnn4C)[C@H](C)C2)c(C)c1 CHEMBL4215775 IC50 1000.0 nM