Nc1ncc(-c2ccnc(Nc3ccncc3)n2)c(CC2CC2)n1 CHEMBL3781415 IC50 0.018 nM
COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CC[C@H](O)[C@@]2(C)C[C@H]1OC(C)=O CHEMBL273832 IC50 0.5 nM
CCN1CCN(c2ccc(Nc3ncnc(N(C)C(=O)Nc4c(Cl)c(OC)c(Cl)c(OC)c4Cl)n3)cc2)CC1 CHEMBL5286775 Kd 0.53 nM
C[C@@H]1COCCN1c1cc(N2CCCC[C@@H]2C(F)(F)F)[nH]c(=O)c1 CHEMBL5404351 Kd 1.0 nM
C[C@@H]1COCCN1c1cc(=O)n2c(n1)N(Cc1cncc(Cl)c1)[C@H](C(F)(F)F)CC2 CHEMBL3622372 IC50 1.2 nM
COCCS(=O)(=O)Nc1cc(-c2cc3c(c(OC[C@H](C)N4CCC(C(C)(C)O)CC4)c2)COC3)cnc1OC CHEMBL4561242 pIC50 1.585 nM
C[C@@H]1CN(CC(=O)Nc2ccc3c(c2)Cc2cccc(-c4cc(=O)cc(N5CCOCC5)o4)c2S3)C[C@H](C)O1 CHEMBL2140173 Kd 1.7 nM
NC(=O)c1ccc2c(c1)OCCc1sc(-c3ncnn3-c3ccc(F)cc3F)nc1-2 CHEMBL5192406 IC50 1.7 nM
COc1ncc(-c2cc3c(c(OCCN4CCC(C(C)(C)O)CC4)c2)COC3)cc1NS(C)(=O)=O CHEMBL4556087 pKd(app) 1.995 nM
CC(C)C(=O)CN1c2nc(N3CCOC[C@H]3C)cc(=O)n2CC[C@H]1C(F)(F)F CHEMBL4586628 IC50 2.0 nM
O=c1cc(N2CCOCC2)nc2n1CC[C@@H](C(F)(F)F)N2C[C@@H](O)c1ccccc1 CHEMBL4517404 IC50 2.0 nM
C[C@H](CN1C[C@@H](C)O[C@@H](C)C1)Oc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4794132 Kd 2.0 nM
O=S(=O)(Nc1cc(-c2ccc3nccc(-c4cccnc4)c3c2)cnc1Cl)c1ccc(F)cc1 CHEMBL1914726 IC50 2.9 nM
O=c1cc(N2CCOCC2)nc2n1CC[C@@H](C(F)(F)F)N2C[C@H](O)c1ccccc1 CHEMBL4536755 IC50 3.0 nM
O=C(Nc1cc2cc(-c3nncn3-c3ccccc3Cl)ccc2cn1)C1CC1F CHEMBL5192215 IC50 3.0 nM
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(C#N)CC2)C(C)(C)C)c(OCCOCCOCCOCCCCCCCl)c1 CHEMBL5267259 DC50 3.0 nM
COCCS(=O)(=O)Nc1cc(-c2cc3c(c(OC[C@@H](C)N4CCC(C(C)(C)O)CC4)c2)COC3)cnc1OC CHEMBL4449047 pIC50 3.162 nM
COC[C@@H](C)Oc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4752634 Kd 4.0 nM
O=c1cc(N2CCOCC2)cc(N2C[C@@H]3C[C@@H]3[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4862803 Ki 4.0 nM
COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O CHEMBL428496 IC50 4.2 nM
O=S(=O)(Nc1cc(-c2ccc3ncc(N4CCOCC4)nc3c2)cnc1Cl)c1ccc(F)cc1 CHEMBL1914743 IC50 5.0 nM
O=c1cc(N2CCOCC2)nc(N2C[C@@H]3C[C@@H]3[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4857803 Ki 5.0 nM
COc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4792737 Kd 5.1 nM
O=S(=O)(Nc1cc(-c2ccc3nccc(-c4ccncc4)c3c2)cnc1Cl)c1ccc(F)cc1 CHEMBL1914727 IC50 5.3 nM
C[C@@H]1CCN(c2nc(N3CCOCC3)cc(=O)[nH]2)[C@H]1Cc1ccccc1 CHEMBL4852400 Ki 6.0 nM
CC(C)OCCN1c2nc(N3CCOCC3)cc(=O)n2CC[C@H]1C(F)(F)F CHEMBL4470174 IC50 7.0 nM
O=c1cc(N2CCOCC2)nc2n1CC[C@@H](C(F)(F)F)N2c1cc(F)cc(F)c1 CHEMBL4536855 IC50 7.0 nM
O=C(/C=C/c1ccccc1)Oc1ccc2c(c1)O/C(=C\C=C\c1ccccc1)C2=O CHEMBL5436994 IC50 7.6 nM
O=c1cc(N2CCOCC2)nc(N2CCCCC[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4850755 Ki 8.0 nM
Nc1ccc(-c2ccc3ncc4ccc(=O)n(-c5cccc(C(F)(F)F)c5)c4c3c2)cn1 CHEMBL1765602 IC50 8.58 nM
O=c1cc(N2CCOCC2)cc(N2CCC[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4873212 Ki 9.0 nM
O=c1cc(N2CCOCC2)nc2n(Cc3cccc(Cl)c3Cl)c(C3CC3)nn12 CHEMBL2018216 pIC50 9.12 nM
O=S(=O)(Nc1cc(-c2ccc3nccc(N4CCOCC4)c3c2)cnc1Cl)c1ccc(F)cc1 CHEMBL1738719 IC50 11.0 nM
CC(C)[C@@H]1CNC(=O)c2cc(-c3ccnc(NC(=O)C4CC4)c3)nn21 CHEMBL5183804 IC50 13.0 nM
CNc1ncc(-c2ccnc(Nc3ccncc3)n2)c(CC2CC2)n1 CHEMBL3780029 IC50 14.0 nM
C[C@H](CN1CCOCC1)Oc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4745255 IC50 14.0 nM
CC(C)(O)CNc1ncc(-c2ccnc(Nc3ccncc3)n2)c(CC2CC2)n1 CHEMBL3781466 IC50 15.0 nM
COc1ncc(-c2cc3c(c(OC[C@H]4CN(CC(C)(C)O)CCO4)c2)COC3)cc1NS(C)(=O)=O CHEMBL4518946 pIC50 15.85 nM
Oc1cc(N2CCOCC2)nc(N2CCC[C@@H]2Cc2ccccc2)n1 CHEMBL4878312 Ki 16.0 nM
COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CCC(=O)[C@@]2(C)CC1 CHEMBL13513 IC50 17.0 nM
COc1ccc(N(C(=O)CCl)C(C(=O)NCCc2ccccc2)c2cccs2)cc1Cl CHEMBL1499544 IC50 18.0 nM
Cc1nc(NC(=O)CN)sc1-c1cnc(Cl)c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c1 CHEMBL4447963 IC50 19.0 nM
Cc1cc(Nc2cc(Cl)nc(Oc3ccc([N+](=O)[O-])cc3)n2)n[nH]1 CHEMBL4639853 IC50 19.0 nM
COc1ncc(-c2cc3c(c(OC[C@H]4CN(C5COC5)CCO4)c2)COC3)cc1NS(C)(=O)=O CHEMBL4436797 pIC50 19.95 nM
O=c1cc(-c2cccc3c2Sc2ccc(OC4COC4)cc2C3)oc(N2CCOCC2)c1 CHEMBL4760480 IC50 20.0 nM
O=C(Nc1cc(-c2ccn3ccnc3c2)ccn1)C1CC1 CHEMBL5190688 IC50 20.0 nM
Cc1cc(Nc2cc(Cl)nc(Oc3ccc([N+](=O)[O-])cc3)n2)no1 CHEMBL5277117 IC50 20.0 nM
Cc1n[nH]c2ccc(-c3nnc4n3[C@H](c3ccc(Cl)cc3)CC4)nc12 CHEMBL5416758 Kd 20.0 nM
O=c1cc(N2CCOCC2)nc(N2C[C@H]3C[C@H]3[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4858310 Ki 21.0 nM
Cc1cc(Nc2cc(C)[nH]n2)nc(Oc2ccc([N+](=O)[O-])cc2)n1 CHEMBL5275440 IC50 23.0 nM
CC(C)(O)CNc1ncc(-c2ccnc(Nc3ccnc(Cl)c3)n2)c(CC2CC2)n1 CHEMBL3913746 IC50 25.0 nM
COCCS(=O)(=O)Nc1cc(-c2cc3c(c(O[C@@H](C)CN4CCC(C(C)(C)O)CC4)c2)COC3)cnc1OC CHEMBL4447804 pIC50 25.12 nM
Cc1nc2sc1-c1cc3c(c(c1)S(=O)(=O)NCCOCCNC(=O)c1cccc(n1)N2)C(=O)N([C@@H](C)C1CC1)C3 CHEMBL5091438 pIC50 25.12 nM
C[C@@H]1COCCN1c1nc(-c2cnc(N)cc2C(F)F)nc(N2CCOCC2(C)C)n1 CHEMBL4741511 Kd 28.0 nM
CC(=O)Nc1nc2ccc(-c3cnc(Cl)c(NS(=O)(=O)c4ccc(F)cc4)c3)cc2s1 CHEMBL1615189 Ki 31.0 nM
Cc1nc(Nc2cccc(N3CCOCC3=O)n2)sc1-c1cc2c(c(S(=O)(=O)NC3COC3)c1)C(=O)N([C@@H](C)C1CC1)C2 CHEMBL5077865 pIC50 31.62 nM
CC(=O)Nc1nc(C)c(-c2ccc(Cl)c(S(=O)(=O)Nc3ccc(O)cc3)c2)s1 CHEMBL3787013 IC50 32.0 nM
CC(C)(C)Nc1ncc(-c2ccnc(Nc3ccncc3)n2)c(CC2CC2)n1 CHEMBL3781926 IC50 35.0 nM
COc1ccc2c(c1)Cc1cccc(-c3cc(O)nc(N4CCOCC4)n3)c1S2 CHEMBL4874992 Ki 35.0 nM
O=[N+]([O-])c1ccc(Oc2nc(Cl)cc(Nc3cc(C4CC4)[nH]n3)n2)cc1 CHEMBL5274326 IC50 36.0 nM
C[C@@H]1COCCN1c1cc2n(n1)C[C@H](C(F)(F)F)NC2=O CHEMBL5203001 IC50 37.0 nM
O=c1cc(N2CCOCC2)cc(N2CCC(F)(F)[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4858974 Ki 39.0 nM
C[C@@H]1COCCN1c1cc2n(n1)[C@H](C(C)(C)C)CNC2=O CHEMBL5184806 IC50 43.0 nM
Cc1cnc(NC(=O)C2CC2)cc1-c1cc2n(n1)[C@H](C(C)C)CNC2=O CHEMBL5200373 IC50 48.0 nM
O=c1cc(N2CCOCC2)cc(N2CCCC2Cc2ccccc2)[nH]1 CHEMBL4873551 Ki 49.0 nM
N#Cc1ccc(Oc2nc(Cl)cc(Nc3cc[nH]n3)n2)cc1 CHEMBL5281192 IC50 49.0 nM
O=c1cc(N2CCOCC2)cc(N2CCCCC[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4872830 Ki 50.0 nM
CCCCN/C=C1\C(=O)O[C@H](COC)[C@@]2(C)C1=C(O)C(=O)C1=C2[C@H](OC(C)=O)C[C@]2(C)C(=O)CC[C@@H]12 CHEMBL5287349 IC50 52.0 nM
O=C(Nc1cc(-n2cnc3ccccc32)ccn1)C1CC1 CHEMBL5181274 IC50 53.0 nM
COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=CC[C@]2(C)C(=O)CC[C@H]2C1C3=O CHEMBL268976 IC50 54.0 nM
COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CCC(OC(C)=O)[C@@]2(C)C[C@H]1OC(C)=O CHEMBL5281260 IC50 59.0 nM
NS(=O)(=O)c1ccc(Oc2nc(Cl)cc(Nc3cc[nH]n3)n2)cc1 CHEMBL5282812 IC50 61.0 nM
COCCS(=O)(=O)Nc1cc(-c2cc3c(c(OC[C@H]4CN(C5COC5)CCO4)c2)COC3)cnc1OC CHEMBL4579923 pKd(app) 63.1 nM
C[C@@H]1COCCN1c1nc(-c2cnc(N)cc2C(F)F)nc(N2[C@H](C)COC[C@@H]2C)n1 CHEMBL4749352 Kd 65.0 nM
O=c1cc(-c2cccc3c2Sc2ccc(O[C@@H]4CCN(CC(F)F)C4)cc2C3)oc(N2CCOCC2)c1 CHEMBL4783168 IC50 67.0 nM
Cc1n[nH]c2ccc(-c3nnc4n3[C@H](c3ccc(Cl)cc3)CC4)cc12 CHEMBL5434183 Kd 68.0 nM
c1ccc(CNc2ncc(-c3ccnc(Nc4ccncc4)n3)c(CC3CC3)n2)cc1 CHEMBL3781615 IC50 76.0 nM
COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2C[C@@H](Br)C(OC(C)=O)[C@@]2(C)C[C@H]1OC(C)=O CHEMBL5270095 IC50 77.0 nM
CC(C)[C@@H]1CNC(=O)c2cc(N3CCOC[C@H]3C)nn21 CHEMBL5193287 IC50 78.0 nM
Cc1cc(Nc2cc(C(F)(F)F)nc(Oc3ccc([N+](=O)[O-])cc3)n2)n[nH]1 CHEMBL5285942 IC50 78.0 nM
CCN(/C=C1\C(=O)O[C@H](COC)[C@@]2(C)C1=C(O)C(=O)C1=C2[C@H](OC(C)=O)C[C@]2(C)C(=O)CC[C@@H]12)CC CHEMBL276865 IC50 80.0 nM
C[C@@H]1COCCN1c1cc2n(n1)[C@@H]1CCC[C@@H]1NC2=O CHEMBL5207217 IC50 83.0 nM
C[C@@H]1COCCN1c1cc2n(n1)[C@H](C1CC1)C1(CC1)NC2=O CHEMBL5201378 IC50 84.0 nM
CC(C)(C)CNc1ncc(-c2ccnc(Nc3ccncc3)n2)c(CC2CC2)n1 CHEMBL3780339 IC50 85.0 nM
COc1ncc(-c2ccnc(Nc3ccncc3)n2)c(CC2CC2)n1 CHEMBL3781634 IC50 91.0 nM
C[C@@H]1COCCN1c1cc2n(n1)[C@H](C(F)(F)F)CNC2=O CHEMBL5197671 IC50 92.0 nM
O=c1cc(N2CCOCC2)cc(N2C[C@H]3C[C@H]3[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4874640 Ki 98.0 nM
COc1ncc(C2=CCOCC2)cc1S(=O)(=O)Nc1cncc(C#CCN2CCN(C(C)C)CC2)c1 CHEMBL4872328 pIC50 100.0 nM
CNc1ncc(-c2ccnc(N[C@H]3CC[C@H](O)CC3)n2)c(CC2CC2)n1 CHEMBL3781916 IC50 110.0 nM
O=c1cc(N2CCOCC2)cc(N2CC[C@@H](F)[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4866506 Ki 110.0 nM
Clc1cc(Nc2cc[nH]n2)nc(OCc2ccncc2)n1 CHEMBL5267007 IC50 110.0 nM
CNc1ncc(-c2ccnc(Nc3ccc(OC)cc3)n2)c(CC2CC2)n1 CHEMBL3781236 IC50 120.0 nM
Cc1cc(Nc2cc(N3CCOCC3)nc(Oc3ccc([N+](=O)[O-])cc3)n2)n[nH]1 CHEMBL5269785 IC50 121.0 nM
CNc1ncc(-c2ccnc(Nc3cnc4ccccc4c3)n2)c(CC2CC2)n1 CHEMBL3782016 IC50 130.0 nM
Nc1ncc(-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)c(C(F)(F)F)n1 CHEMBL4102855 Kd 130.0 nM
COc1ccc2c(c1)Cc1cccc(-c3cc(N4CCOCC4)cc(=O)[nH]3)c1S2 CHEMBL4879094 Ki 130.0 nM
C[C@@H]1CNC(=O)c2cc(-c3ccnc(NC(=O)C4CC4)c3)nn21 CHEMBL5195258 IC50 130.0 nM
CC1COc2cc(C(N)=O)ccc2-c2nc(-c3ncnn3-c3ccc(F)cc3F)sc21 CHEMBL5197817 IC50 130.0 nM
CC(=O)Nc1nc(C)c(-c2ccc(Br)c(S(=O)(=O)NCCO)c2)s1 CHEMBL3787634 IC50 146.0 nM
Cc1cc(Nc2cc(N3CCN(C)CC3)nc(Oc3ccc([N+](=O)[O-])cc3)n2)n[nH]1 CHEMBL3604928 IC50 146.0 nM
O=C1Nc2ccc(-c3cccnc3)cc2C1=Cc1cc(Br)c(O)c(Br)c1 CHEMBL1851668 pIC50 151.36 nM
COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2C[C@@H](O)C(OC(C)=O)[C@@]2(C)C[C@H]1OC(C)=O CHEMBL5275891 IC50 153.0 nM
CN1CCC(NC(=O)c2ccc(-c3ccc(-n4c(=O)ccc5cnc6ccc(-c7cnc8ccccc8c7)cc6c54)cc3C(F)(F)F)cc2)CC1 CHEMBL1795875 IC50 170.0 nM
O=c1cc(N2CCOCC2)cc(N2CCCC[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4846084 Ki 170.0 nM
C[C@@H]1COCCN1c1cc2n(n1)[C@H](C(C)(C)O)CNC2=O CHEMBL5192969 IC50 170.0 nM
C[C@@H]1NC(=O)c2cc(N3CCOC[C@H]3C)nn2[C@@H]1C1CC1 CHEMBL5206758 IC50 170.0 nM
C[C@H]1Cc2ccccc2N1C(=O)Cc1nc(N2CCOCC2)cc(=O)[nH]1 CHEMBL3112866 IC50 183.0 nM
Nc1cc(C(F)(F)F)c(-c2cc(N3CCOCC3)nc(N3CCOCC3)n2)cn1 CHEMBL2017974 Kd 200.0 nM
c1cc(Nc2nccc(-c3cncnc3CC3CC3)n2)ccn1 CHEMBL3781020 IC50 210.0 nM
Cc1cc(Nc2cc(Cl)nc(OCc3ccc([N+](=O)[O-])cc3)n2)n[nH]1 CHEMBL5273375 IC50 214.0 nM
Nc1cc(C(F)(F)F)c(-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)cn1 CHEMBL4084907 Kd 230.0 nM
c1cc(Nc2nccc(-c3cnc(NC4CCOCC4)nc3CC3CC3)n2)ccn1 CHEMBL3780762 IC50 240.0 nM
C[C@@H]1COCCN1c1cc2n(n1)[C@H](C1CC1)CNC2=O CHEMBL5202968 IC50 240.0 nM
C[C@@H]1COCCN1c1cc2n(n1)[C@H](C1CCC1)CNC2=O CHEMBL5194297 IC50 240.0 nM
CC(=O)Nc1nc(C)c(-c2ccc(Cl)c(S(=O)(=O)Nc3ccc(F)cc3)c2)s1 CHEMBL3787054 IC50 245.4 nM
Cc1c(CN2CCN(C(=O)[C@H](C)O)CC2)sc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc12 CHEMBL1922094 Kd 250.0 nM
Oc1cc(N2CCC[C@@H]2Cc2ccccc2)nc(N2CCOCC2)n1 CHEMBL4852165 Ki 270.0 nM
COC[C@H]1OC(=O)C2=CCOC3=C2[C@@]1(C)C1=C(C3=O)[C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O CHEMBL276894 IC50 271.0 nM
Cc1cc(Nc2cc(N(C)C)nc(Oc3ccc([N+](=O)[O-])cc3)n2)n[nH]1 CHEMBL5272049 IC50 285.0 nM
CNc1ncc(-c2ccnc(Nc3ccccc3)n2)c(CC2CC2)n1 CHEMBL3780896 IC50 290.0 nM
CC(=O)/N=c1/[nH]c(C)c(-c2ccc(Cl)c(S(=O)(=O)NCCO)c2)s1 CHEMBL1229535 IC50 307.0 nM
COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2C[C@@H](OC(C)=O)C(OC(C)=O)[C@@]2(C)C[C@H]1OC(C)=O CHEMBL5279542 IC50 309.0 nM
Cc1cc(Nc2cc(C(F)(F)F)nc(Nc3ccc([N+](=O)[O-])cc3)n2)n[nH]1 CHEMBL5278884 IC50 310.0 nM
NC(=O)c1ccccc1Nc1ccnc(NC(=O)C2CC2)c1 CHEMBL5190274 IC50 320.0 nM
C[C@@H]1COCCN1c1cc2n(n1)[C@H](C1CCCC1)CNC2=O CHEMBL5203298 IC50 350.0 nM
Cc1nc(-c2cn3c(n2)-c2ccc(-c4cnn(C(C)(C)C(N)=O)c4)cc2OCC3)n(C(C)C)n1 CHEMBL2387080 IC50 374.0 nM
COc1ncc(-c2cc3c(c(OCCN4CCC(C(C)(C)O)CC4)c2)CCOC3)cc1NS(C)(=O)=O CHEMBL4466265 pIC50 398.11 nM
CNc1ncc(-c2ccnc(NC3CCOCC3)n2)c(CC2CC2)n1 CHEMBL3781964 IC50 400.0 nM
Cc1ccc(S(=O)(=O)Nc2cc(-c3sc(NC(=O)[C@@H](N)C(C)C)nc3C)cnc2Cl)cc1 CHEMBL4164334 IC50 405.0 nM
CNc1ncc(-c2ccnc(N[C@H]3CC[C@H](N)CC3)n2)c(CC2CC2)n1 CHEMBL3780864 IC50 410.0 nM
c1ccc2sc(-c3cnn4cccnc34)nc2c1 CHEMBL4632827 Kd 410.0 nM
C[C@@H]1COCCC1c1cc(=O)n2c(n1)N(Cc1cncc(Cl)c1)[C@H](C(F)(F)F)CC2 CHEMBL5290510 IC50 419.0 nM
Cn1c(=O)n(-c2ccc(C(C)(C)C#N)cc2)c2c3cc(-c4cnc5ccccc5c4)ccc3ncc21 CHEMBL1879463 IC50 450.0 nM
Cn1ccc(-c2ccnc(NC(=O)C3CC3)c2)cc1=O CHEMBL5204287 IC50 470.0 nM
Cc1nc(Nc2cccc(N3CCCC3=O)n2)sc1-c1cc2c(c(S(C)(=O)=O)c1)C(=O)N([C@@H](C)C1CC1)C2 CHEMBL4558527 pIC50 501.19 nM
CCC(=O)N1CCN(c2ccc(-n3c(=O)ccc4cnc5ccc(-c6cnc7ccccc7c6)cc5c43)cc2C(F)(F)F)CC1 CHEMBL1256459 IC50 533.0 nM
C[C@@H]1COCCN1c1cc2n(n1)[C@H](C1CC1)[C@H](C1CC1)NC2=O CHEMBL5202909 IC50 560.0 nM
Cc1nc(N)nc(-c2cc(Cl)cnc2Nc2cnc(Cl)c(NS(=O)(=O)N(C)C)c2)n1 CHEMBL2206921 IC50 606.0 nM
CC(C)(C)c1cc(Nc2cc(Cl)nc(Oc3ccc([N+](=O)[O-])cc3)n2)n[nH]1 CHEMBL5267751 IC50 627.0 nM
O=c1cc(N2CCOCC2)cc(N2CCC[C@H]2Cc2ccccc2)[nH]1 CHEMBL4851518 Ki 630.0 nM
CNC(=O)c1cncc(-c2cnc(Cl)c(NS(=O)(=O)c3ccccc3)c2)c1 CHEMBL4752128 IC50 681.0 nM
CC(C)[C@@H]1CNC(=O)c2cc(N3CCOCC3)nn21 CHEMBL5182171 IC50 710.0 nM
Fc1ccc(CNc2ncnc3ccc(F)cc23)cc1 CHEMBL2391504 IC50 740.0 nM
C[C@@H]1CN(c2cc(N3C[C@@H]4C[C@@H]4[C@@H]3Cc3ccccc3)[nH]c(=O)c2)CCO1 CHEMBL4856420 Ki 750.0 nM
COc1ccc2c(c1OC)N=C(NC(=O)c1cccnc1)N1CCN=C21 CHEMBL1241857 IC50 830.0 nM
Cc1ccccc1S(=O)(=O)Nc1cc(-c2sc(NC(=O)[C@@H](N)C(C)C)nc2C)cnc1Cl CHEMBL4161766 IC50 834.0 nM
C[C@@H]1CN(c2cc(=O)[nH]c(N3CCCCC[C@@H]3Cc3ccccc3)n2)CCO1 CHEMBL4852763 Ki 840.0 nM
C[C@@H]1CN(c2cc(=O)[nH]c(N3C[C@H]4C[C@H]4[C@@H]3Cc3ccccc3)n2)CCO1 CHEMBL4867495 Ki 880.0 nM
COc1ccc2c(c1)Cc1cccc(-c3cc(N4CCOCC4)cc(=O)n3C)c1S2 CHEMBL4872413 Ki 910.0 nM
C[C@@H]1COCCN1c1nc(-c2cnc(N)nc2)nc2c1C[C@@H]1COCCN21 CHEMBL4436124 Kd 980.0 nM
CC[C@H](Nc1ncnc2[nH]cnc12)c1nc2cccc(F)c2c(=O)n1-c1ccccc1 CHEMBL2216870 IC50 980.0 nM