Cc1cccc(/C=N/Nc2cc(N3CCOCC3)nc(OCCc3ccccn3)n2)c1 CHEMBL4297643 Kd 0.075 nM
Nc1ccc(C(=O)Nc2cccc(-c3nc(N4CCOCC4)c4oc5ncccc5c4n3)c2)cn1 CHEMBL2178735 IC50 0.82 nM
Cc1cccc(/C=N/Nc2cc(N3CCOCC3)n3nc(-c4ccncc4)cc3n2)c1 CHEMBL4303292 IC50 1.19 nM
CCC(O)(CC)c1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3 CHEMBL5189479 IC50 1.8 nM
CCC(C)(O)c1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3 CHEMBL5193848 IC50 1.9 nM
CC(C)(O)C#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3 CHEMBL2334586 IC50 2.2 nM
CN(C)CC#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3 CHEMBL5174830 pIC50 3.981 nM
CC(O)c1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3 CHEMBL5171359 IC50 4.05 nM
CC(C)(O)C#Cc1ccc2[nH]cc(-c3ccnc(N)n3)c2c1 CHEMBL5181163 IC50 6.1 nM
COC(C)(C)c1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3 CHEMBL5198944 IC50 6.2 nM
COc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)c2[nH]ccc2n1 CHEMBL5420130 Kd 6.4 nM
Nc1ncc2c(n1)-c1c([nH]c3ccc(-c4ccc(F)cc4)cc13)CC2 CHEMBL5207387 IC50 8.2 nM
Ic1cccc(/C=N/Nc2nc(N3CCOCC3)nc(N(c3ccccc3)c3ccccc3)n2)c1 CHEMBL5194705 IC50 9.0 nM
Nc1ncc2c(n1)-c1c([nH]c3ccc(-c4ccc(F)cc4)cc13)CCC2 CHEMBL5171753 IC50 9.3 nM
Nc1ncc2c(n1)-c1c([nH]c3ccc(C#Cc4ccncc4)cc13)CCC2 CHEMBL5190524 IC50 22.0 nM
Cn1cc(-c2ccc3[nH]c4c(c3c2)-c2nc(N)ncc2CCC4)cn1 CHEMBL5188159 IC50 26.0 nM
Cn1cc(-c2ccc3[nH]c4c(c3c2)-c2nc(N)ncc2CC4)cn1 CHEMBL5200109 IC50 34.0 nM
Nc1ncc2c(n1)-c1c([nH]c3ccc(CCO)cc13)CCC2 CHEMBL5185288 IC50 40.0 nM
CN(C)C/C=C/C(=O)Nc1ccc(C(=O)Nc2cccc(Nc3cc(-c4c[nH]c5ccccc45)ncn3)c2)cc1 CHEMBL4446338 IC50 40.1 nM
CC(C)C(O)C#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3 CHEMBL5190153 IC50 45.7 nM
CC(C)(O)C#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCCC3 CHEMBL5202422 IC50 61.0 nM
Nc1ncc2c(n1)-c1c([nH]c3ccc(C#CC4CC4)cc13)CCCC2 CHEMBL5190724 IC50 75.0 nM
Cn1cncc1C#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CC3 CHEMBL5192827 IC50 77.0 nM
CN(C)CC#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CC3 CHEMBL5187698 IC50 123.0 nM
CC(C)(NS(C)(=O)=O)c1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3 CHEMBL5184182 IC50 140.0 nM
CC(C)(O)C#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CC3 CHEMBL5194568 IC50 220.0 nM
CN(C)C/C=C/C(=O)Nc1ccc(C(=O)N2CC[C@H](Nc3nccc(-c4c(-c5ccccc5)nn5ccccc45)n3)C2)cc1 CHEMBL5413843 Kd 270.0 nM
Cn1cncc1C#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCCC3 CHEMBL5203403 IC50 290.0 nM
CC(C)(O)Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3 CHEMBL5194935 IC50 290.0 nM
Nc1ncc2c(n1)-c1c([nH]c3ccc(C#CC4CC4)cc13)CC2 CHEMBL5194053 IC50 300.0 nM
CN(C)CC#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCCC3 CHEMBL5190455 IC50 430.0 nM
Nc1ncc2c(n1)-c1c([nH]c3ccc(C#Cc4ccncc4)cc13)CCCC2 CHEMBL5204874 IC50 580.0 nM
Nc1ncc2c(n1)-c1c([nH]c3ccc(C4CC4)cc13)CCCC2 CHEMBL5199026 IC50 715.0 nM
COc1cc2c(-c3cnc(-c4ccc[nH]4)o3)c[nH]c2cc1Br CHEMBL4564337 Kd 1000.0 nM