O=S(=O)(c1ccc2ccccc2c1)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1 CHEMBL1093996 Potency 0.02 nM
Cc1cc2c(s1)c1cnn(Cc3ccc(F)c(F)c3F)c(=O)c1n2C CHEMBL1082796 Potency 0.0251 nM
O=S(=O)(c1ccc(Cl)cc1)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1 CHEMBL1091504 Potency 0.0282 nM
CCCCCn1ncc2c3sc(C)cc3n(C)c2c1=O CHEMBL1083136 Potency 0.0316 nM
CC(C)c1cc2c(s1)c1cnn(Cc3ccccc3F)c(=O)c1n2C CHEMBL1083166 Potency 0.0316 nM
O=S(=O)(c1c(F)cccc1F)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1 CHEMBL1093369 Potency 0.0355 nM
Cn1c2ccsc2c2ncn(Cc3ccccc3F)c(=O)c21 CHEMBL1084057 Potency 0.0355 nM
COc1ccc(Cn2ncc3c4sc(C)cc4n(C)c3c2=O)cc1 CHEMBL1082456 Potency 0.0447 nM
Cn1c2cc(C#N)sc2c2cnn(Cc3ccccc3F)c(=O)c21 CHEMBL1085873 Potency 0.0562 nM
Cc1cc2[nH]c3c(=O)n(Cc4ccccc4F)ncc3c2s1 CHEMBL1085410 Potency 0.1 nM
Cc1cc2c(s1)c1cnn(Cc3ccccc3F)c(=O)c1n2C(C)C CHEMBL1085412 Potency 0.1 nM
O=S(=O)(NC1CCN(S(=O)(=O)c2c(F)cccc2F)C1)c1ccc2c(c1)OCCO2 CHEMBL1092471 Potency 0.1 nM
Cc1cc2c(s1)c1cnn(Cc3cccc(Cl)c3)c(=O)c1n2C CHEMBL1086540 Potency 0.2 nM
COc1ccc(S(=O)(=O)N2CCN(S(=O)(=O)c3c(F)cccc3F)CC2)cc1 CHEMBL1089366 Potency 0.4 nM
CSc1cc2c(s1)c1cnn(Cc3ccccc3F)c(=O)c1n2C CHEMBL1086565 Potency 0.4 nM
C[C@@H]1CN(S(=O)(=O)c2ccc3c(c2)OCCO3)CCN1S(=O)(=O)c1c(F)cccc1F CHEMBL1088748 Potency 0.4 nM
CC1(C)CCc2cc(S(=O)(=O)N3CCN(S(=O)(=O)c4c(F)cccc4F)CC3)ccc2O1 CHEMBL1090711 Potency 0.4 nM
Cc1cc2c(s1)c1cnn(Cc3ccc(C(F)(F)F)cc3)c(=O)c1n2C CHEMBL1082455 Potency 0.4 nM
O=C(CN1C(=O)N/C(=C\c2cccn2-c2cccc(C(=O)O)c2)C1=O)Nc1ccccc1F CHEMBL1551624 Potency 0.6 nM
Cc1cc2c(s1)c1cnn(Cc3ccc(S(C)(=O)=O)cc3)c(=O)c1n2C CHEMBL1323190 Potency 1.0 nM
Cc1cc2c(s1)c1cnn(-c3ccccc3)c(=O)c1n2C CHEMBL1084058 Potency 1.3 nM
O=S(=O)(NCCCCCNS(=O)(=O)c1c(F)cccc1F)c1ccc2c(c1)OCCO2 CHEMBL1093091 Potency 1.8 nM
CCn1c2cc(C)sc2c2cnn(Cc3ccccc3F)c(=O)c21 CHEMBL1085411 Potency 2.2 nM
O=S(=O)(NC1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1)c1c(F)cccc1F CHEMBL1092121 Potency 2.2 nM
Cc1cc2c(s1)c1cnn(Cc3cccc(F)c3F)c(=O)c1n2C CHEMBL1083728 Potency 2.2 nM
CN1CCOc2ccc(S(=O)(=O)N3CCN(S(=O)(=O)c4c(F)cccc4F)CC3)cc21 CHEMBL1093688 Potency 2.2 nM
Cc1cc2c(s1)c1cnn(Cc3cccc(F)c3)c(=O)c1n2C CHEMBL1086320 Potency 2.5 nM
O=C1CN(S(=O)(=O)c2ccc3c(c2)OCCO3)CCN1S(=O)(=O)c1c(F)cccc1F CHEMBL1093096 Potency 3.2 nM
CCc1cc2c(s1)c1cnn(Cc3ccccc3F)c(=O)c1n2C CHEMBL1083165 Potency 3.5 nM
O=S(=O)(c1c(F)cccc1F)C1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1 CHEMBL1089364 Potency 3.5 nM
O=S(=O)(N[C@H]1CC[C@H](NS(=O)(=O)c2c(F)cccc2F)CC1)c1ccc2c(c1)OCCO2 CHEMBL1093093 Potency 4.5 nM
CCCc1cc(F)c(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc4c(c3)OCCO4)CC2)cc1F CHEMBL1315562 Potency 6.3 nM
COc1ccc(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc4c(c3)OCCO4)CC2)cc1 CHEMBL1088762 Potency 8.9 nM
C[C@H]1CN(S(=O)(=O)c2ccc3c(c2)OCCO3)CCN1S(=O)(=O)c1c(F)cccc1F CHEMBL1088747 Potency 10.0 nM
COc1cc(F)c(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc4c(c3)OCCO4)CC2)c(F)c1 CHEMBL1091078 Potency 12.6 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(S(=O)(=O)c2c(F)ccc(O)c2F)CC1 CHEMBL1090753 Potency 15.8 nM
Cc1cc2c(s1)c1cnn(Cc3ccccc3F)c(=O)c1n2C CHEMBL1084625 Potency 15.8 nM
O=C1CN(S(=O)(=O)c2c(F)cccc2F)CCN1S(=O)(=O)c1ccc2c(c1)OCCO2 CHEMBL1089059 Potency 17.8 nM
O=S(=O)(c1ccc2c(c1)OCCO2)C1CCN(S(=O)(=O)c2c(F)cccc2F)CC1 CHEMBL1091057 Potency 20.0 nM
O=S(=O)(NCCNS(=O)(=O)c1c(F)cccc1F)c1ccc2c(c1)OCCO2 CHEMBL1091458 Potency 22.4 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(S(=O)(=O)c2ccc(F)cc2F)CC1 CHEMBL1089603 Potency 22.4 nM
Cc1cc2c(s1)c1cnn(Cc3ccccc3Cl)c(=O)c1n2C CHEMBL1086539 Potency 25.1 nM
COc1cccc(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc4c(c3)OCCO4)CC2)c1 CHEMBL1092462 Potency 25.1 nM
Cc1ccc(Cn2ncc3c4sc(C)cc4n(C)c3c2=O)cc1 CHEMBL1082454 Potency 28.2 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCN(CC2CC2)CC1 CHEMBL4299940 AC50 29.0 nM
O=S(=O)(NCCCCNS(=O)(=O)c1c(F)cccc1F)c1ccc2c(c1)OCCO2 CHEMBL1091795 Potency 31.6 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(S(=O)(=O)c2cc(F)c(F)cc2F)CC1 CHEMBL1092297 Potency 35.5 nM
O=C(c1ccc2c(c1)OCCO2)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1 CHEMBL1092480 Potency 35.5 nM
O=S(=O)(c1ccc(F)cc1)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1 CHEMBL1090774 Potency 44.7 nM
Cc1cc2c(s1)c1cnn(Cc3ccc(C)c(F)c3F)c(=O)c1n2C CHEMBL1591871 Potency 44.7 nM
N#Cc1ccc(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc4c(c3)OCCO4)CC2)cc1 CHEMBL1091503 Potency 56.2 nM
Cc1cc2c(s1)c1cnn(Cc3cccc(Cn4ncc5c6sc(C)cc6n(C)c5c4=O)c3F)c(=O)c1n2C CHEMBL1475784 Potency 63.1 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1 CHEMBL1091501 Potency 70.8 nM
COc1ccc(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc(OC)cc3)CC2)cc1 CHEMBL1091502 Potency 79.4 nM
Cc1ccc(Cn2ncc3c4sc(C)cc4n(C)c3c2=O)c(C)c1 CHEMBL1396401 Potency 79.4 nM
Cc1cc2c(s1)c1cnn(Cc3ccc(-c4ccccc4)cc3)c(=O)c1n2C CHEMBL1360157 Potency 89.1 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(S(=O)(=O)c2ccccn2)CC1 CHEMBL1092463 Potency 89.1 nM
Cc1nc2ccc(S(=O)(=O)N3CCN(S(=O)(=O)c4c(F)cccc4F)CC3)cc2s1 CHEMBL1513933 Potency 89.1 nM
O=S(=O)(c1ccccc1)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1 CHEMBL1094006 Potency 100.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(Cc2cccc(C(F)(F)F)c2)CC1 CHEMBL3732561 AC50 101.0 nM
COc1cc(NS(=O)(=O)c2cccc3cccnc23)ccc1C(=O)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3728355 AC50 101.0 nM
Cc1nc(C2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5cccnc45)cc3)CC2)ccc1F CHEMBL3729723 AC50 101.0 nM
COc1ccccc1C1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3732269 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(Cc2cccnc2)CC1 CHEMBL3727380 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3ccoc23)cc1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3730962 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(Cc2ccccn2)CC1 CHEMBL3732746 AC50 101.0 nM
Cc1ccc(C2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5cccnc45)cc3)CC2)c(Cl)c1 CHEMBL3731904 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cc(F)cc3cccnc23)cc1)N1CCC(O)(c2ccccc2)CC1 CHEMBL3730546 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3ccccc23)cc1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3733227 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2ccc3nsnc3c2)cc1)N1CCC(O)(Cc2ccccc2)CC1 CHEMBL3727825 AC50 101.0 nM
Cc1cccc(CC2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5cccnc45)cc3)CC2)n1 CHEMBL3728648 AC50 101.0 nM
Cc1nc(C(=O)N2CCC(O)(c3ccccc3Cl)CC2)ccc1NS(=O)(=O)c1cccc2cccnc12 CHEMBL3729336 AC50 101.0 nM
COc1ncccc1C1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3727945 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(c2ccccc2C(F)F)CC1 CHEMBL3728122 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2cccnc2F)CC1 CHEMBL3728251 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cc(F)cc3cccnc23)cc1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3728608 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3ccc(F)nc23)cc1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3729403 AC50 101.0 nM
COCCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3731497 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)c2ccccc12)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3731935 AC50 101.0 nM
Cc1nc(F)ccc1C1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3ccc(F)c4cccnc34)cc2)CC1 CHEMBL3728057 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc(Cl)c2Cl)cc1)N1CCC(O)(Cc2ccccc2)CC1 CHEMBL3729298 AC50 101.0 nM
CC(C)(O)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3729451 AC50 101.0 nM
CC(C)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4ocnc34)cc2)CC1 CHEMBL3733139 AC50 101.0 nM
CC(F)(F)CCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4scnc34)cc2)CC1 CHEMBL3729994 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(CCC(F)=C(F)F)CC1 CHEMBL3731243 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cc(F)cc3scnc23)cc1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3728339 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(/C=C/CC(F)(F)F)CC1 CHEMBL3727915 AC50 101.0 nM
CC(CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4scnc34)cc2)CC1)C(F)F CHEMBL3731819 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3c(O)ncnc23)cc1)N1CCC(O)(/C=C/CC(F)(F)F)CC1 CHEMBL3728225 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3c(O)ncnc23)cc1)N1CCC(O)(CCC(F)(F)F)CC1 CHEMBL3732452 AC50 101.0 nM
Nc1nc2c(S(=O)(=O)Nc3ccc(C(=O)N4CCC(O)(CCC(F)(F)F)CC4)cc3)cccc2s1 CHEMBL3731144 AC50 101.0 nM
CC(CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4c(O)ncnc34)cc2)CC1)C(F)(F)F CHEMBL3729064 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(CC2CC2(F)F)CC1 CHEMBL3729057 AC50 101.0 nM
Cn1nccc1CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4scnc34)cc2)CC1 CHEMBL3729395 AC50 101.0 nM
Cn1cc(CC2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5scnc45)cc3)CC2)cn1 CHEMBL3730000 AC50 101.0 nM
CC(F)(F)CCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cc(F)cc4sc(N)nc34)cc2)CC1 CHEMBL3730677 AC50 101.0 nM
CC(F)(F)CCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4nccnc34)cc2OC(F)F)CC1 CHEMBL3729108 AC50 101.0 nM
CC(F)(F)CCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4scnc34)cc2OC(F)F)CC1 CHEMBL3727429 AC50 101.0 nM
CC(F)(F)CCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4nccnc34)cc2F)CC1 CHEMBL3729954 AC50 101.0 nM
Cc1cc(C2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5scnc45)cc3)CC2)sn1 CHEMBL3729684 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(c2scnc2Cl)CC1 CHEMBL3728823 AC50 101.0 nM
CC(F)(F)CCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cc(F)cc4sc(N)nc34)cc2F)CC1 CHEMBL3729745 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(Cc2nc(Cl)cs2)CC1 CHEMBL3729438 AC50 101.0 nM
CC(F)(F)CCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cc(F)cc4sc(N)nc34)cc2C#N)CC1 CHEMBL3731126 AC50 101.0 nM
CC(F)(F)CCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4nccnc34)cc2C#N)CC1 CHEMBL3730243 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(Cc2cn[nH]c2)CC1 CHEMBL3728569 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)cc1)N1CCC(O)(Cc2cn[nH]c2)CC1 CHEMBL3729439 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)cc1)N1CCC(O)(Cc2cc[nH]n2)CC1 CHEMBL3731762 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(C2CCC(O)CC2)CC1 CHEMBL3733100 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)cc1)N1CCC(O)(C2CCC(O)CC2)CC1 CHEMBL3730681 AC50 101.0 nM
Cc1cc(CC2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5nccnc45)cc3)CC2)sn1 CHEMBL3732749 AC50 101.0 nM
Cc1n[nH]c(C)c1CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4nccnc34)cc2)CC1 CHEMBL3732558 AC50 101.0 nM
Cc1n[nH]c(C)c1CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4scnc34)cc2)CC1 CHEMBL3728532 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(c2ccns2)CC1 CHEMBL3727671 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)cc1)N1CCC(O)(c2ccns2)CC1 CHEMBL3731155 AC50 101.0 nM
Cc1cc(C2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5nccnc45)cc3)CC2)sn1 CHEMBL3733188 AC50 101.0 nM
Cc1noc(C)c1CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4scnc34)cc2)CC1 CHEMBL3729893 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)cc1)N1CCC(O)(Cc2c(O)n[nH]c2C(F)(F)F)CC1 CHEMBL3728102 AC50 101.0 nM
CC(C)CC1(OP(=O)(O)O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4nccnc34)cc2)CC1 CHEMBL3729315 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CC(Oc2ccccc2)C1 CHEMBL3731780 AC50 101.0 nM
Cc1cc(C(=O)N2CC(NC(=O)c3ccccn3)C2)ccc1NS(=O)(=O)c1cccc2cccnc12 CHEMBL3731441 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CC(OCc2ccccc2)C1 CHEMBL3731526 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CC(O)(c2ccccc2)C1 CHEMBL3732219 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CC(O)(Cc2ccccc2)C1 CHEMBL3732472 AC50 101.0 nM
Cc1cc(C(=O)N2CC(Oc3ccccc3)C2)ccc1NS(=O)(=O)c1cccc2cccnc12 CHEMBL3728120 AC50 101.0 nM
Cc1cc(C(=O)N2CC(Nc3ccccn3)C2)ccc1NS(=O)(=O)c1cccc2cccnc12 CHEMBL3732436 AC50 101.0 nM
Cc1cccc(CC2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5cccnc45)cc3)CC2)c1 CHEMBL3730284 AC50 101.0 nM
COc1cccc(CC2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5cccnc45)cc3)CC2)c1 CHEMBL3727803 AC50 101.0 nM
Cc1cc(NS(=O)(=O)c2cccc3cccnc23)ccc1C(=O)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3732101 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2cccc(F)c2)CC1 CHEMBL3732526 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(Cc2cccc(F)n2)CC1 CHEMBL3732693 AC50 101.0 nM
Cc1ncccc1C1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3733226 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2ncccc2F)CC1 CHEMBL3730171 AC50 101.0 nM
Cc1cccnc1C1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3732980 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3729821 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2ccccc2)CC1 CHEMBL3730678 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1Cl)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3731856 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2cccnc2C(F)(F)F)CC1 CHEMBL3731643 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2ccncc2Cl)CC1 CHEMBL3731187 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)cc1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3728469 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)c(F)c1)N1CCC(O)(Cc2ccccc2)CC1 CHEMBL3732377 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2ncccc2C(F)(F)F)CC1 CHEMBL3729049 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2ccccc2F)CC1 CHEMBL3731224 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2cc(F)ccc2Cl)CC1 CHEMBL3731675 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(Cc2cccnc2F)CC1 CHEMBL3731645 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(Cc2cccc(F)c2F)CC1 CHEMBL3729037 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2cccc(C(F)(F)F)n2)CC1 CHEMBL3729506 AC50 101.0 nM
Cc1cc(C(=O)N2CCC(O)(c3cccc(F)c3F)CC2)ccc1NS(=O)(=O)c1cccc2nccnc12 CHEMBL3728131 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(CC2CC2(F)F)CC1 CHEMBL3727804 AC50 101.0 nM
Cc1cc(C(=O)N2CCC(O)(c3cccc(Cl)c3)CC2)ccc1NS(=O)(=O)c1cccc2cccnc12 CHEMBL3731218 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(c2cccc(F)c2F)CC1 CHEMBL3728465 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2ccc(F)c3cccnc23)cc1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3729860 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2cnsc2)CC1 CHEMBL3727633 AC50 101.0 nM
C=C(C)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4scnc34)cc2)CC1 CHEMBL3727452 AC50 101.0 nM
CCCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3728780 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)cc1)N1CCC(O)(CC2CC2)CC1 CHEMBL3729808 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2ncccc2Cl)CC1 CHEMBL3728269 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1F)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3729011 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2ccc(F)cc2)CC1 CHEMBL3731420 AC50 101.0 nM
CC(C)(C)C1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3729025 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(CC2CC2)CC1 CHEMBL3732015 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2cccc(C(F)(F)F)c2)CC1 CHEMBL3732945 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(/C=C/C(F)F)CC1 CHEMBL3729797 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2ccc(F)c3cccnc23)cc1)N1CCC(O)(CC2CCC2)CC1 CHEMBL3730290 AC50 101.0 nM
CC(C)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cc(F)cc4scnc34)cc2)CC1 CHEMBL3730232 AC50 101.0 nM
CC(C)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3ccc(F)c4cccnc34)cc2)CC1 CHEMBL3728514 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(CCC(F)F)CC1 CHEMBL3733007 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2ccc(F)c3cccnc23)cc1)N1CCC(O)(Cc2ccccc2C(F)(F)F)CC1 CHEMBL3733027 AC50 101.0 nM
N#Cc1cc(NS(=O)(=O)c2cccc3cccnc23)ccc1C(=O)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3731546 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(CC2CCC2)CC1 CHEMBL3732598 AC50 101.0 nM
CC(C)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4nccnc34)cc2OC(F)F)CC1 CHEMBL3732969 AC50 101.0 nM
CC(C)C1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3730769 AC50 101.0 nM
CC(C)CC1(CO)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4scnc34)cc2)CC1 CHEMBL3731834 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cc(F)cnc23)cc1)N1CCC(O)(c2ccccc2)CC1 CHEMBL3729081 AC50 101.0 nM
CC(C)CC1(CO)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4nccnc34)cc2)CC1 CHEMBL3731482 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2ccc(F)c3nccnc23)cc1)N1CCC(O)(c2cccc(F)c2F)CC1 CHEMBL3732399 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)cc1)N1CCC(O)(CCC(F)(F)F)CC1 CHEMBL3730613 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)c(Cl)c1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3727972 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2ccc(F)c3cccnc23)cc1)N1CCC(O)(c2cccc(F)c2F)CC1 CHEMBL3732451 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)cc1)N1CCC(O)(CCC(F)F)CC1 CHEMBL3732905 AC50 101.0 nM
O=C(c1c(F)cc(NS(=O)(=O)c2cccc3cccnc23)cc1F)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3732790 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(CCC(F)(F)F)CC1 CHEMBL3730068 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2ccc(F)c3nccnc23)cc1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3730830 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(CCC(F)F)CC1 CHEMBL3729200 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2ccccc2Cl)cc1)N1CCC(O)(Cc2ccccc2)CC1 CHEMBL3729180 AC50 101.0 nM
CC(C)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3ccc(F)c4scnc34)cc2)CC1 CHEMBL3731238 AC50 101.0 nM
CC(C)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3ccc(F)c4nccnc34)cc2)CC1 CHEMBL3729188 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)c(F)c1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3728624 AC50 101.0 nM
CC(C)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3ccc(F)c(N)c3N)cc2)CC1 CHEMBL3731556 AC50 101.0 nM
CC(C)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)c(C(F)F)c2)CC1 CHEMBL3727583 AC50 101.0 nM
N#Cc1cc(NS(=O)(=O)c2cccc3cccnc23)ccc1C(=O)N1CCC(O)(c2ccccc2)CC1 CHEMBL3728230 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)c(F)c1)N1CCC(O)(c2cccc(F)c2F)CC1 CHEMBL3731601 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)c(OC(F)F)c1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3732713 AC50 101.0 nM
CC(C)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc(O)c3N)cc2)CC1 CHEMBL3728399 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3ocnc23)cc1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3730320 AC50 101.0 nM
Nc1c(O)cccc1S(=O)(=O)Nc1ccc(C(=O)N2CCC(O)(c3ccccc3Cl)CC2)cc1 CHEMBL3730038 AC50 101.0 nM
Cc1nc2c(S(=O)(=O)Nc3ccc(C(=O)N4CCC(O)(c5ccccc5Cl)CC4)cc3)cccc2o1 CHEMBL3729704 AC50 101.0 nM
Cc1nc2c(S(=O)(=O)Nc3ccc(C(=O)N4CCC(O)(CC(C)C)CC4)cc3)cccc2o1 CHEMBL3729620 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(COCC(F)(F)F)CC1 CHEMBL3733231 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(CCC=C(F)F)CC1 CHEMBL3728498 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(CCCC(F)(F)F)CC1 CHEMBL3732251 AC50 101.0 nM
CC(F)(F)CCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4nccnc34)cc2)CC1 CHEMBL3728504 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)cc1)N1CCC(O)(CCC(F)=C(F)F)CC1 CHEMBL3727977 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)cc1)N1CCC(O)(CCCC(F)F)CC1 CHEMBL3731821 AC50 101.0 nM
CC(C)(F)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4scnc34)cc2)CC1 CHEMBL3727693 AC50 101.0 nM
Cn1cc(C2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5scnc45)cc3)CC2)cn1 CHEMBL3727743 AC50 101.0 nM
CC(F)(F)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4scnc34)cc2)CC1 CHEMBL3731444 AC50 101.0 nM
CC(C)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4c3OCO4)cc2)CC1 CHEMBL3728331 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3c(O)ncnc23)cc1)N1CCC(O)(c2cccc(F)c2F)CC1 CHEMBL3733051 AC50 101.0 nM
CC(F)(F)CCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4scnc34)cc2F)CC1 CHEMBL3728835 AC50 101.0 nM
CC(F)(F)CCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4nc(N)cnc34)cc2)CC1 CHEMBL3733174 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)cc1)N1CCC(O)(Cc2nc(Cl)cs2)CC1 CHEMBL3730707 AC50 101.0 nM
CC1(O)CCC(C2(O)CCN(C(=O)c3ccc(NSc4cccc5nccnc45)cc3)CC2)CC1 CHEMBL3730602 AC50 101.0 nM
Cn1nccc1CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4nccnc34)cc2)CC1 CHEMBL3732776 AC50 101.0 nM
CC(C)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cncc4cccnc34)cc2)CC1 CHEMBL3732830 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)cc1)N1CCC(O)(c2sncc2Cl)CC1 CHEMBL3732139 AC50 101.0 nM
Cc1noc(C)c1CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4nccnc34)cc2)CC1 CHEMBL3730249 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(c2sncc2Cl)CC1 CHEMBL3732332 AC50 101.0 nM
CC(C)CC1(OC(=O)OCOP(=O)(O)O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4scnc34)cc2)CC1 CHEMBL3731941 AC50 101.0 nM
CC(C)CC1(OC(=O)OCOP(=O)(O)O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4nccnc34)cc2)CC1 CHEMBL3729290 AC50 101.0 nM
CC(C)CC1(N)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4scnc34)cc2)CC1 CHEMBL3728909 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2ccc(F)c3scnc23)cc1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3730200 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(CO)(c2ccccc2)CC1 CHEMBL3731627 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)cc1)N1CCC(O)(c2ccccc2)CC1 CHEMBL3730449 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3csnc23)cc1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3727441 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2cccc(OC(F)(F)F)c2)CC1 CHEMBL3731824 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2ccnc(F)c2)CC1 CHEMBL3733328 AC50 101.0 nM
CCOC(=O)C1(CC(C)C)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3729452 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(CCCO)CC1 CHEMBL3727416 AC50 101.0 nM
N#Cc1ccc(C2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5cccnc45)cc3)CC2)cc1 CHEMBL3730617 AC50 101.0 nM
Nc1c(F)ccc(S(=O)(=O)Nc2ccc(C(=O)N3CCC(O)(c4ccccc4Cl)CC3)cc2)c1N CHEMBL3728461 AC50 101.0 nM
CC(C)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4csnc34)cc2)CC1 CHEMBL3729310 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nc(F)ccc23)cc1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3727585 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(C2CC2)CC1 CHEMBL3729712 AC50 101.0 nM
Cc1cccc(C2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5cccnc45)cc3)CC2)n1 CHEMBL3731301 AC50 101.0 nM
N#Cc1ccccc1C1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3729444 AC50 101.0 nM
CCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3728064 AC50 101.0 nM
CN1C(=O)C=C2C=C(S(=O)(=O)Nc3ccc(C(=O)N4CCC(O)(Cc5ccccc5)CC4)cc3)C=CC21 CHEMBL3732996 AC50 101.0 nM
CC(C)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3csc4cccnc34)cc2)CC1 CHEMBL3732129 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)c(OC(F)(F)F)c1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3728941 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(c2ccccc2-c2ccccc2Cl)CC1 CHEMBL3728929 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(Cc2cccnn2)CC1 CHEMBL3730127 AC50 101.0 nM
N#Cc1cc(C(=O)N2CCC(O)(c3ccccc3Cl)CC2)ccc1NS(=O)(=O)c1cccc2cccnc12 CHEMBL3727787 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(CCO)CC1 CHEMBL3730872 AC50 101.0 nM
CC(O)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3729598 AC50 101.0 nM
COc1cccc(C2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5cccnc45)cc3)CC2)c1 CHEMBL3732458 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2ccc(F)c3cccnc23)c(F)c1)N1CCC(O)(c2cccc(F)c2F)CC1 CHEMBL3729790 AC50 101.0 nM
N#Cc1cccc(C2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5cccnc45)cc3)CC2)c1 CHEMBL3731425 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2csc3cccnc23)cc1)N1CCC(O)(c2ccccc2Cl)CC1 CHEMBL3731361 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc(Cl)c2)cc1)N1CCC(O)(Cc2ccccc2)CC1 CHEMBL3727819 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cnccc23)cc1)N1CCC(O)(Cc2ccccc2)CC1 CHEMBL3728537 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2cccc3c2OCCO3)CC1 CHEMBL3730137 AC50 101.0 nM
COc1cccnc1C1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3728572 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2cccc(F)n2)CC1 CHEMBL3729679 AC50 101.0 nM
CC(C)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3ccc(O)c4nccnc34)cc2)CC1 CHEMBL3733146 AC50 101.0 nM
O=C(c1cc(F)c(NS(=O)(=O)c2cccc3cccnc23)cc1F)N1CCC(O)(c2ccccc2)CC1 CHEMBL3729074 AC50 101.0 nM
Cc1nc2c(S(=O)(=O)Nc3ccc(C(=O)N4CCC(O)(c5ccccc5Cl)CC4)cc3)cccc2s1 CHEMBL3732520 AC50 101.0 nM
CCOC(=O)C1(Cc2ccccc2)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3728118 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(c2cn[nH]c2)CC1 CHEMBL3731920 AC50 101.0 nM
Nc1nc2c(S(=O)(=O)Nc3ccc(C(=O)N4CCC(O)(/C=C/CC(F)(F)F)CC4)cc3)cccc2s1 CHEMBL3731801 AC50 101.0 nM
CC(C)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cncnc34)cc2)CC1 CHEMBL3732704 AC50 101.0 nM
CS(=O)(=O)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4scnc34)cc2)CC1 CHEMBL3728568 AC50 101.0 nM
CS(=O)(=O)CC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4nccnc34)cc2)CC1 CHEMBL3728076 AC50 101.0 nM
CC(F)(F)CCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4scnc34)cc2C#N)CC1 CHEMBL3727885 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(c2nc(Cl)cs2)CC1 CHEMBL3731479 AC50 101.0 nM
CN1CCC(CC2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5scnc45)cc3)CC2)C1=O CHEMBL3731650 AC50 101.0 nM
CCn1cc(CC2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5nccnc45)cc3)CC2)cn1 CHEMBL3730374 AC50 101.0 nM
Cn1ccc(CC2(O)CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc5nccnc45)cc3)CC2)n1 CHEMBL3730421 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3scnc23)cc1)N1CCC(O)(c2ncc(Cl)s2)CC1 CHEMBL3727939 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3nccnc23)cc1)N1CCC(O)(c2ncc(Cl)s2)CC1 CHEMBL3730648 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2ccccc2O)CC1 CHEMBL3728183 AC50 101.0 nM
CCOCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3732174 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc(C(F)(F)F)c2)cc1)N1CCC(O)(Cc2ccccc2)CC1 CHEMBL3729784 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2ccc3c(c2)OCO3)cc1)N1CCC(O)(Cc2ccccc2)CC1 CHEMBL3729317 AC50 101.0 nM
CC(C)(O)CCC1(O)CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3731625 AC50 101.0 nM
CC1(O)CCC(C2(O)CCN(C(=O)c3ccc(NSc4cccc5scnc45)cc3)CC2)CC1 CHEMBL3727986 AC50 101.0 nM
COc1cc(NS(=O)(=O)c2cccc3cccnc23)ccc1C(=O)N1CCC(O)(Cc2ccccc2)CC1 CHEMBL3732143 AC50 101.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(O)(c2ccccc2OC(F)(F)F)CC1 CHEMBL3729041 AC50 101.0 nM
Cn1c2ccsc2c2cnn(Cc3ccccc3F)c(=O)c21 CHEMBL1083475 Potency 112.2 nM
O=S(=O)(Nc1ccc(O)c(O)c1)c1cc(O)c(O)cc1-c1ccc(O)c(O)c1 CHEMBL5429790 IC50 120.0 nM
Cc1cc2c(s1)c1cnn(Cc3ccc(C(F)(F)F)cc3F)c(=O)c1n2C CHEMBL1085340 Potency 141.3 nM
O=C1c2ccccc2C(=O)c2c1cc(S(=O)(=O)N1CCNCC1)c(O)c2O CHEMBL5204170 IC50 150.0 nM
O=S(=O)(NCC1CN(S(=O)(=O)c2c(F)cccc2F)C1)c1ccc2c(c1)OCCO2 CHEMBL1093061 Potency 158.5 nM
O=C1c2ccccc2C(=O)c2c1cc(S(=O)(=O)N1CCCC(C(=O)O)C1)c(O)c2O CHEMBL5209097 IC50 160.0 nM
Cc1cc2c(s1)c1cnn(Cc3ccc(C(C)C)cc3)c(=O)c1n2C CHEMBL1524808 Potency 177.8 nM
Cc1cc2c(s1)c1cnn(Cc3c(F)c(F)cc(F)c3F)c(=O)c1n2C CHEMBL1082797 Potency 177.8 nM
O=C1c2ccccc2C(=O)c2c1cc(S(=O)(=O)[O-])c(O)c2O CHEMBL175336 IC50 200.0 nM
O=C(O)CNS(=O)(=O)c1cc2c(c(O)c1O)C(=O)c1ccccc1C2=O CHEMBL5176753 IC50 200.0 nM
O=C(O)CC(O)(CC(=O)N1CCN(S(=O)(=O)c2cc3c(c(O)c2O)C(=O)c2ccccc2C3=O)CC1)C(=O)O CHEMBL5208105 IC50 200.0 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(S(=O)(=O)c2ccccc2F)CC1 CHEMBL1090776 Potency 251.2 nM
Cn1ccc2cc(S(=O)(=O)N3CCN(S(=O)(=O)c4c(F)cccc4F)CC3)ccc21 CHEMBL1091055 Potency 251.2 nM
CSc1cc2c(s1)c1cnn(Cc3cccc(O)c3)c(=O)c1n2C CHEMBL1481562 Potency 259.0 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1 CHEMBL1090777 Potency 281.8 nM
O=S(=O)(NCC1CN(S(=O)(=O)c2ccc3c(c2)OCCO3)C1)c1c(F)cccc1F CHEMBL1093360 Potency 281.8 nM
O=C(O)Cc1ccc(CNC(=O)N2CCN(S(=O)(=O)c3cc4c(c(O)c3O)C(=O)c3ccccc3C4=O)CC2)cc1C(=O)O CHEMBL5176181 IC50 290.0 nM
O=C(O)Cc1ccc(CNS(=O)(=O)c2cc3c(c(O)c2O)C(=O)c2ccccc2C3=O)cc1C(=O)O CHEMBL5181251 IC50 300.0 nM
Fc1ccccc1-c1ccc(-c2nc3ccc(Cl)cn3c2Nc2ccc(Cl)cc2)o1 CHEMBL1473999 Potency 326.1 nM
Cn1c2cc(C=O)sc2c2cnn(Cc3ccccc3F)c(=O)c21 CHEMBL1085647 Potency 398.1 nM
Cc1cc2c(s1)c1cnn(Cc3c(F)cccc3F)c(=O)c1n2C CHEMBL1085794 Potency 446.7 nM
O=S(=O)(c1cccc(F)c1)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1 CHEMBL1090775 Potency 501.2 nM
O=C(O)CC[C@H](NC(=O)N1CCN(S(=O)(=O)c2cc3c(c(O)c2O)C(=O)c2ccccc2C3=O)CC1)C(=O)O CHEMBL5204537 IC50 550.0 nM
Cc1ccccc1Nc1c(-c2ccccc2)nc2cccc(C)n12 CHEMBL1356205 Potency 579.9 nM
CC(=O)c1cc2c(s1)c1cnn(Cc3ccccc3F)c(=O)c1n2C CHEMBL1084899 Potency 631.0 nM
Cc1cc2c(s1)c1cnn(Cc3c(F)cccc3Cl)c(=O)c1n2C CHEMBL1084029 Potency 631.0 nM
COc1ccc(Cn2ncc3c4sc(C)cc4n(C)c3c2=O)cc1F CHEMBL1085586 Potency 631.0 nM
O=C(O)CNC(=O)CNC(=O)CNS(=O)(=O)c1cc2c(c(O)c1O)C(=O)c1ccccc1C2=O CHEMBL5188496 IC50 700.0 nM
O=S(=O)(c1ccc2c(c1)OCO2)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1 CHEMBL1093687 Potency 794.3 nM
O=C1c2ccccc2C(=O)c2c1cc(S(=O)(=O)N[C@@H](CO)C(=O)O)c(O)c2O CHEMBL5183208 IC50 900.0 nM
Cc1cc2c(s1)c1cnn(Cc3ccc(F)cc3F)c(=O)c1n2C CHEMBL1082457 Potency 1000.0 nM
CC(O)c1cc2c(s1)c1cnn(Cc3ccccc3F)c(=O)c1n2C CHEMBL1085147 Potency 1000.0 nM