Cc1cc2c(s1)c1cnn(Cc3ccc(F)c(F)c3F)c(=O)c1n2C CHEMBL1082796 Potency 0.0178 nM
C[C@@H]1CN(S(=O)(=O)c2ccc3c(c2)OCCO3)CCN1S(=O)(=O)c1c(F)cccc1F CHEMBL1088748 Potency 0.0282 nM
Cn1c2cc(C=O)sc2c2cnn(Cc3ccccc3F)c(=O)c21 CHEMBL1085647 Potency 0.0316 nM
O=C(c1ccc2c(c1)OCCO2)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1 CHEMBL1092480 Potency 0.0398 nM
Cc1cc2c(s1)c1cnn(Cc3ccc(C(C)C)cc3)c(=O)c1n2C CHEMBL1524808 Potency 0.0398 nM
O=c1[nH]c2ccc(S(=O)(=O)N3CCN(S(=O)(=O)c4c(F)cccc4F)CC3)cc2[nH]c1=O CHEMBL3392462 Potency 0.0631 nM
COC(=O)C1=CN(CC2CCCO2)C=C(C(=O)OC)C1c1cc(OC)c(OC)c(OC)c1 CHEMBL1540684 Potency 0.08913 nM
Cc1cc2c(s1)c1cnn(Cc3ccccc3Cl)c(=O)c1n2C CHEMBL1086539 Potency 0.1 nM
Cc1cc2[nH]c3c(=O)n(Cc4ccccc4F)ncc3c2s1 CHEMBL1085410 Potency 0.1 nM
O=c1c(O)c(-c2cc(O)c(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL164 EC50 0.51 nM
CCn1c2ccccc2c2nnc(SCC(=O)Nc3cc(C)on3)nc21 CHEMBL1376724 Potency 0.7 nM
Cc1ccc(Cn2ncc3c4sc(C)cc4n(C)c3c2=O)c(C)c1 CHEMBL1396401 Potency 0.7 nM
Cc1cc2c(s1)c1cnn(Cc3cc(C(F)(F)F)cc(Cl)c3F)c(=O)c1n2C CHEMBL1435175 Potency 1.1 nM
O=c1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL250450 EC50 1.34 nM
COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O CHEMBL1418590 Potency 1.6 nM
O=S(=O)(NCCNS(=O)(=O)c1c(F)cccc1F)c1ccc2c(c1)OCCO2 CHEMBL1091458 Potency 1.8 nM
O=S(=O)(NC1CCN(S(=O)(=O)c2c(F)cccc2F)C1)c1ccc2c(c1)OCCO2 CHEMBL1092471 Potency 1.8 nM
O=S(=O)(N[C@H]1CC[C@@H](NS(=O)(=O)c2c(F)cccc2F)CC1)c1ccc2c(c1)OCCO2 CHEMBL1091831 Potency 2.2 nM
Cc1ccc(C(=O)OC(C(=O)O)C(OC(=O)c2ccc(C)cc2)C(=O)O)cc1 CHEMBL2448607 Potency 2.5 nM
Cc1csc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4c(c3)oc(=O)n4C)C2)n1 CHEMBL1303801 Potency 3.2 nM
N#C/C(=C\c1ccc(O)c(O)c1)C(=O)NCCc1ccccc1 CHEMBL293749 Potency 3.2 nM
OCc1c[nH]cn1 CHEMBL1397797 Potency 3.2 nM
CSc1cc2c(s1)c1cnn(Cc3ccccc3F)c(=O)c1n2C CHEMBL1086565 Potency 3.2 nM
Cn1cc(C(=O)c2cccc(Cl)c2Cl)cc1C(=O)NCNC(=O)c1cc(C(=O)c2cccc(Cl)c2Cl)cn1C CHEMBL4071498 AC50 3.2 nM
CN(Cc1ccccc1)C(=O)C1CCCN(Cc2ccc(Cl)cc2)C1 CHEMBL1455935 Potency 5.0 nM
CCN(CC)CC#CCOC(=O)[C@@](O)(c1ccccc1)C1CCCCC1 CHEMBL1394756 Potency 5.0 nM
N[C@H](CCC(=O)O)C(=O)O CHEMBL76232 Potency 5.0 nM
O=C(CCCN1CCC(O)(c2cccc(C(F)(F)F)c2)CC1)c1ccc(F)cc1 CHEMBL15023 Potency 5.0 nM
CC(C)Oc1ccc(CCC(=O)NN=C(S)NCc2ccccc2)cc1 CHEMBL1469921 Potency 5.6 nM
CN1CCC(N(C)CC(=O)Nc2cccc(Oc3ccccc3)c2)CC1 CHEMBL1581079 Potency 5.6 nM
COc1ccc(N(C(C)C(=O)Nc2ccc(S(=O)(=O)N3CCOCC3)cc2)S(C)(=O)=O)cc1 CHEMBL1581017 Potency 5.6 nM
C=C1C(=O)O[C@H]2[C@H]1CCC(C)=C1CC[C@@](C)(O)[C@@H]12 CHEMBL449579 EC50 6.0 nM
C=C1C(=O)O[C@H]2C1CCC(C)=C1CC[C@@](C)(O)[C@@H]12 CHEMBL5286069 AC50 6.0 nM
O=C(CCc1nc2ccccc2s1)N1CCN(S(=O)(=O)c2cccs2)CC1 CHEMBL1527980 Potency 6.3 nM
CNC(=O)c1cc2c(=O)n3cc(C)ccc3nc2n(C(C)C)c1=N CHEMBL1336339 Potency 6.3 nM
Cc1ccc(O)c(NC(=O)CCC2CCCCC2)c1 CHEMBL1367311 Potency 6.3 nM
Cc1cccc(N(C(=O)c2snc(C(N)=O)c2N)C(C)C(=O)NCC2CCCO2)c1 CHEMBL1460632 Potency 6.3 nM
Cc1cc(C)c2nc(O)c(C(c3nnnn3Cc3ccc4c(c3)OCO4)N3CCCCC3)cc2c1 CHEMBL1377716 Potency 6.3 nM
Cc1cc(C)cc(NC(=O)CSc2nnc(-c3ccccc3)n2N)c1 CHEMBL1612225 Potency 6.3 nM
N#C/C(=C\c1ccc(O)c(O)c1)C(=O)NCc1ccccc1 CHEMBL56543 Potency 6.3 nM
Cn1cnc2c(NC3CCCC3)ncnc21 CHEMBL48278 Potency 6.3 nM
Oc1cc2c(c(Cl)c1O)CCNC[C@H]2c1ccccc1 CHEMBL1317463 Potency 6.3 nM
Cc1nc2sccn2c(=O)c1CCN1CCC(=C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL267777 Potency 6.3 nM
Cc1nc2ccccn2c(=O)c1CCN1CCC(C(=O)c2ccc(F)cc2)CC1 CHEMBL18331 Potency 6.3 nM
CCCN(CCC)[C@H]1CCc2c(F)ccc(O)c2C1 CHEMBL22778 Potency 6.3 nM
Cc1cc2c(s1)c1cnn(Cc3ccc(-c4ccccc4)cc3)c(=O)c1n2C CHEMBL1360157 Potency 6.3 nM
O=C1CN(S(=O)(=O)c2ccc3c(c2)OCCO3)CCN1S(=O)(=O)c1c(F)cccc1F CHEMBL1093096 Potency 6.3 nM
Cc1c(OC(C)C(=O)N[C@H](C(=O)O)c2ccccc2)ccc2c3c(c(=O)oc12)CCCC3 CHEMBL1316971 Potency 7.1 nM
CCCCn1c(=O)c(C(=O)Nc2cnccn2)c(O)c2ccccc21 CHEMBL1334593 Potency 7.1 nM
Clc1ccccc1CSc1nnc(-c2cccnc2)n1Cc1ccco1 CHEMBL1479572 Potency 7.1 nM
CC(=O)c1cc2c(s1)c1cnn(Cc3ccccc3F)c(=O)c1n2C CHEMBL1084899 Potency 7.1 nM
N#Cc1ccc(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc4c(c3)OCCO4)CC2)cc1 CHEMBL1091503 Potency 7.1 nM
Nc1cccc(F)c1CN(CCC1CCS(=O)(=O)CC1)C(=O)c1cc(C(F)(F)F)n[nH]1 CHEMBL5274026 EC50 7.126 nM
CCNC(=O)C(Sc1ccccc1)c1ccccc1 CHEMBL1597654 Potency 7.9 nM
COc1ccc(C(=O)Oc2c(CN3CCOCC3)cc(Cl)c3cccnc23)cc1 CHEMBL1481374 Potency 7.9 nM
O=C(NC1CSC/C1=N\O)c1ccccc1 CHEMBL3214275 Potency 7.9 nM
Clc1ccc(Cn2c(CN3CCCC3)nc3ccccc32)cc1 CHEMBL1407943 Potency 7.9 nM
N/C(S)=N/CCC[C@@H](N)C(=O)O CHEMBL168461 Potency 7.9 nM
COc1ccc2c(c1)c(CC(=O)N1CCOCC1)c(C)n2C(=O)c1ccc(Cl)cc1 CHEMBL72631 Potency 7.9 nM
Oc1ccc2c3c1O[C@@H]1[C@@H](O)CC[C@]4(O)[C@H](C2)N(CC2CCC2)CC[C@@]314 CHEMBL1434950 Potency 7.9 nM
O=C1c2ccccc2C(O)N1Cc1ccco1 CHEMBL1437959 Potency 8.9 nM
COc1cc(NC(=O)C2CCN(S(=O)(=O)c3ccc(Cl)cc3)CC2)ccc1-n1cnnn1 CHEMBL1446015 Potency 10.0 nM
CC(=O)OCC1=C(C(=O)[O-])N2C(=O)[C@@H](NC(=O)Cc3cccs3)[C@@H]2SC1 CHEMBL1370610 Potency 10.0 nM
NC(=O)OCC(COC(N)=O)c1ccccc1 CHEMBL1094 Potency 10.0 nM
CNC1(C)C2CCC(C2)C1(C)C CHEMBL267936 Potency 10.0 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(S(=O)(=O)c2cc(F)c(F)cc2F)CC1 CHEMBL1092297 Potency 10.0 nM
COc1cc(F)c(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc4c(c3)OCCO4)CC2)c(F)c1 CHEMBL1091078 Potency 10.0 nM
COc1ccccc1N1CCN(C(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)CC1 CHEMBL3335791 AC50 10.0 nM
O=C(c1cc(C(F)(F)F)n[nH]1)N(Cc1ccc(O)cc1F)CC1CCC1 CHEMBL3104587 AC50 10.0 nM
Cn1cc(C(=O)c2cccc(Cl)c2Cl)cc1C(=O)NCCNC(=O)c1cc(C(=O)c2cccc(Cl)c2Cl)cn1C CHEMBL4070458 AC50 10.0 nM
Cc1cc2c(s1)c1cnn(Cc3ccccc3F)c(=O)c1n2Cc1ccccc1F CHEMBL1486545 Potency 11.2 nM
CC(=O)Oc1cc(C(C)C)c(OCCN(C)C)cc1C CHEMBL159226 Potency 12.6 nM
O=C(OCCN1CCOCC1)C1(c2ccccc2)CCCCC1 CHEMBL305881 Potency 12.6 nM
C#CCN(C)[C@@H](C)Cc1ccccc1 CHEMBL16857 Potency 12.6 nM
O=c1onc2n1-c1cc(Br)ccc1OC2 CHEMBL507122 Potency 12.6 nM
Cn1c2cc([N+](=O)[O-])sc2c2cnn(Cc3ccccc3F)c(=O)c21 CHEMBL1086349 Potency 12.7 nM
O=C(CN1C(=O)N/C(=C\c2cccn2-c2cccc(C(=O)O)c2)C1=O)Nc1ccccc1F CHEMBL1551624 Potency 14.1 nM
CC(O)c1cc2c(s1)c1cnn(Cc3ccccc3F)c(=O)c1n2C CHEMBL1085147 Potency 14.1 nM
C=C1C(=O)O[C@H]2[C@H]1CC/C(C(=O)OCCOCCOC(=O)/C1=C/CC[C@@]3(C)O[C@H]3[C@H]3OC(=O)C(=C)[C@@H]3CC1)=C\CC[C@@]1(C)O[C@@H]21 CHEMBL4466655 AC50 15.0 nM
C=C1C(=O)O[C@@H]2[C@H]3O[C@]3(C)CC/C=C(/C(=O)OCCOCCOC(=O)/C3=C/CC[C@@]4(C)O[C@@H]4[C@H]4OC(=O)C(=C)[C@@H]4CC3)CC[C@@H]12 CHEMBL5267914 AC50 15.0 nM
Cn1c2cc([S+](C)[O-])sc2c2cnn(Cc3ccccc3F)c(=O)c21 CHEMBL1086566 Potency 16.0 nM
CCN1CCC(CN(C(=O)[C@@H]2CCN(Cc3ccccc3)C2)c2ccc([As]3SCCS3)cc2)CC1 CHEMBL5396216 IC50 16.0 nM
CC[C@]1(C2=NCCN2)Cc2ccccc2O1 CHEMBL1357517 Potency 20.0 nM
COc1ccc(Cn2ncc3c4sc(C)cc4n(C)c3c2=O)cc1 CHEMBL1082456 Potency 20.1 nM
COc1cccc(NS(=O)(=O)c2cc3c(cc2Cl)NC(=O)CO3)c1 CHEMBL2385099 EC50 22.0 nM
Cn1c2cc(C#N)sc2c2cnn(Cc3ccccc3F)c(=O)c21 CHEMBL1085873 Potency 22.5 nM
O=C(COP(=O)(O)O)[C@@H](O)[C@H](O)[C@H](O)COP(=O)(O)O CHEMBL1235112 AC50 23.0 nM
O=P(O)(O)OC[C@H]1O[C@](O)(COP(=O)(O)O)[C@@H](O)[C@@H]1O CHEMBL97893 EC50 23.0 nM
COc1ccccc1C1=Nn2c(nnc2C2CCCCC2)SC1 CHEMBL1310511 Potency 25.1 nM
O=C(O)c1cccnc1Nc1cccc(C(F)(F)F)c1 CHEMBL63323 Potency 25.1 nM
O=c1[nH]c2ccccc2n1CCCN1CCN(C(c2ccccc2)c2ccccc2)CC1 CHEMBL13828 Potency 25.1 nM
O=S(=O)(c1ccc2ccccc2c1)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1 CHEMBL1093996 Potency 25.1 nM
Cc1cc2c(s1)c1cnn(Cc3ccc(F)cc3F)c(=O)c1n2C CHEMBL1082457 Potency 25.3 nM
Cc1cc2c(s1)c1cnn(Cc3ccc(F)cc3)c(=O)c1n2C CHEMBL1086538 Potency 25.3 nM
Cc1cc2c(s1)c1cnn(Cc3c(F)cccc3F)c(=O)c1n2C CHEMBL1085794 Potency 25.3 nM
COc1cc(F)c(S(=O)(=O)N2CCN(S(=O)(=O)c3cccc(N)c3)CC2)c(F)c1 CHEMBL1091760 AC50 26.0 nM
O=C(CC(c1ccccc1)c1ccccc1)NCC1CCCO1 CHEMBL1523936 Potency 28.2 nM
CC1(C)CCc2cc(S(=O)(=O)N3CCN(S(=O)(=O)c4c(F)cccc4F)CC3)ccc2O1 CHEMBL1090711 Potency 28.2 nM
COc1ccc(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc(OC)cc3)CC2)cc1 CHEMBL1091502 Potency 28.2 nM
Cn1c2cc(CO)sc2c2cnn(Cc3ccccc3F)c(=O)c21 CHEMBL1085648 Potency 28.4 nM
Nc1cccc(S(=O)(=O)N2CCCN(S(=O)(=O)c3ccc4c(c3)OCCO4)CC2)c1 CHEMBL1089334 AC50 30.0 nM
CC1CN(c2nc3c(c(=O)[nH]c(=O)n3C)n2Cc2ccccc2F)CC(C)O1 CHEMBL1381560 Potency 31.6 nM
N[C@H](Cc1ccc(Cl)cc1)C(=O)O CHEMBL1355710 Potency 31.6 nM
Cc1cnc(NC(=O)C2=C([O-])c3ccccc3S(=O)(=O)N2C)s1 CHEMBL1256873 Potency 31.6 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(S(=O)(=O)c2c(F)ccc(O)c2F)CC1 CHEMBL1090753 Potency 31.8 nM
O=C(c1cc(Br)n[nH]1)N(Cc1ccc(O)cc1F)CC1CCC1 CHEMBL3104580 AC50 34.0 nM
Cc1cc2c(s1)c1cnn(Cc3cccc(C)c3F)c(=O)c1n2C CHEMBL1082798 AC50 35.0 nM
CSc1ccccc1C(=O)Nc1nccs1 CHEMBL1406724 Potency 35.5 nM
CN1CCOc2ccc(S(=O)(=O)N3CCN(S(=O)(=O)c4c(F)cccc4F)CC3)cc21 CHEMBL1093688 Potency 35.5 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1 CHEMBL1090777 Potency 35.7 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCN(CC2CC2)CC1 CHEMBL4299940 EC50 37.0 nM
Cc1cc2c(s1)c1cnn(Cc3ccccc3F)c(=O)c1n2C CHEMBL1084625 EC50 38.0 nM
COC(=O)c1cc2c(s1)c1cnn(Cc3ccccc3F)c(=O)c1n2C CHEMBL1085874 Potency 39.1 nM
CCOC(=O)c1c(C)[nH]c(C(=O)CN2C(=O)NC(C)(c3ccc(C)cc3)C2=O)c1C CHEMBL1346930 Potency 39.8 nM
COC(=O)C1(S(=O)(=O)c2ccc(C)cc2)CCOCC1 CHEMBL1509858 Potency 39.8 nM
COc1ccc(C2CC(C(F)(F)F)n3nc(C(=O)NCc4c(C)nn(C)c4C)c(Cl)c3N2)cc1 CHEMBL1373869 Potency 39.8 nM
CC(=O)Nc1ccc(S(=O)(=O)N2CCN(c3nc(NC4CCCC4)c4ccccc4n3)CC2)cc1 CHEMBL546597 Potency 39.8 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1 CHEMBL1091501 Potency 39.8 nM
Cc1cc2c(s1)c1cnn(Cc3ccc(C(F)(F)F)cc3)c(=O)c1n2C CHEMBL1082455 Potency 39.8 nM
Cc1cc2c(s1)c1cnn(Cc3cccc(F)c3F)c(=O)c1n2C CHEMBL1083728 Potency 39.8 nM
Cc1cc2c(s1)c1cnn(Cc3c(F)cccc3Cl)c(=O)c1n2C CHEMBL1084029 Potency 40.1 nM
COc1cc2c(s1)c1cnn(Cc3ccccc3F)c(=O)c1n2C CHEMBL1083882 Potency 40.1 nM
Nc1cccc(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc4c(c3)OCCO4)CC2)c1 CHEMBL1089607 AC50 43.0 nM
Cc1cc(C)c2c(c1)-c1c(ssc1=S)C(C)(C)N2C(=O)CSc1nncn1C CHEMBL1411788 Potency 44.7 nM
CCc1cc2c(s1)c1cnn(Cc3ccccc3F)c(=O)c1n2C CHEMBL1083165 Potency 44.7 nM
Cc1cc2c(s1)c1cnn(Cc3ccccc3)c(=O)c1n2C CHEMBL1083137 Potency 45.0 nM
CS(=O)(=O)N1CCc2cc(S(=O)(=O)c3ccc4c(c3)OCCO4)ccc21 CHEMBL2178676 AC50 45.0 nM
C=C1C(=O)O[C@H]2[C@H]1CCC(C)=C1CC[C@@](C)(OC(=O)CCCc3cn(CCOCCOCCOCCNC(=O)CCCC[C@H]4SC[C@H]5NC(=O)N[C@H]54)nn3)[C@@H]12 CHEMBL4218770 Ki 50.0 nM
CCOC(=O)/C(=C\c1ccc(B(O)O)cc1)C(=O)c1sc(Nc2ccc(Cl)cc2)nc1N(C)C CHEMBL4878027 AC50 50.0 nM
CO[C@H]1C[C@@H]2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@H]([C@H](C)C[C@@H]2CC[C@@H](O)[C@H](OC)C2)CC(=O)[C@H](C)/C=C(\C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)/C=C/C=C/C=C/1C CHEMBL413 IC50 50.0 nM
N=C(N)c1ccc(OCCCCCOc2ccc(C(=N)N)cc2)cc1 CHEMBL361506 Potency 50.1 nM
O=C1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@@H]1O5 CHEMBL1437711 Potency 50.1 nM
CCCc1cc(F)c(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc4c(c3)OCCO4)CC2)cc1F CHEMBL1315562 Potency 50.1 nM
O=S(=O)(c1c(F)cccc1F)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1 CHEMBL1093369 Potency 50.5 nM
COc1cc(F)c(S(=O)(=O)N2CCN(S(=O)(=O)c3cccs3)CC2)c(F)c1 CHEMBL1595109 Potency 51.7 nM
C=C1C(=O)O[C@H]2[C@H]1CC/C(C(=O)OCCOCCOCCOC(=O)/C1=C/CC[C@@]3(C)O[C@H]3[C@H]3OC(=O)C(=C)[C@@H]3CC1)=C\CC[C@@]1(C)O[C@@H]21 CHEMBL4591115 AC50 52.0 nM
O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCC(C(=S)SCc2cccnc2)CC1 CHEMBL5179096 EC50 56.0 nM
O=S(=O)(c1ccc(F)cc1)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1 CHEMBL1090774 Potency 56.6 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(S(=O)(=O)c2ccccc2F)CC1 CHEMBL1090776 Potency 56.6 nM
O=S(=O)(c1ccc(Cl)cc1)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1 CHEMBL1091504 Potency 56.6 nM
Cc1cc2c(s1)c1cnn(Cc3ccc(C)c(F)c3F)c(=O)c1n2C CHEMBL1591871 Potency 56.6 nM
COc1ccc(S(=O)(=O)N2CCN(S(=O)(=O)c3c(F)cccc3F)CC2)cc1 CHEMBL1089366 Potency 56.6 nM
COc1cc(F)c(S(=O)(=O)N2CCCN(S(=O)(=O)c3ccc4c(c3)OCCO4)CC2)c(F)c1 CHEMBL1473385 Potency 58.0 nM
Cc1ccc(NS(=O)(=O)c2cc3c(cc2N[C@@H](C)CO)NC(=O)CC3)cc1Cl CHEMBL1939112 EC50 60.0 nM
O=C(c1cc(Cl)n[nH]1)N(Cc1ccc(O)cc1F)CC1CCC1 CHEMBL3104584 AC50 62.0 nM
Cc1sc(NC(=O)c2ccccc2)c(C(c2ccccn2)N2CCN(CCO)CC2)c1C CHEMBL1359204 Potency 63.1 nM
N=C(N)c1ccccc1 CHEMBL20936 Potency 63.1 nM
COc1cccc(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc4c(c3)OCCO4)CC2)c1 CHEMBL1092462 Potency 63.5 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1CCN(S(=O)(=O)c2ccc(F)cc2F)CC1 CHEMBL1089603 Potency 63.5 nM
Cc1nc2ccc(S(=O)(=O)N3CCN(S(=O)(=O)c4c(F)cccc4F)CC3)cc2s1 CHEMBL1513933 Potency 63.5 nM
C=C1C(=O)O[C@H]2[C@H]1CC/C(C(=O)OCCOCCOCCOCCOCCOCCOCCOCCOC(=O)/C1=C/CC[C@@]3(C)O[C@H]3[C@H]3OC(=O)C(=C)[C@@H]3CC1)=C\CC[C@@]1(C)O[C@@H]21 CHEMBL4543609 AC50 65.0 nM
CSc1cc2c(s1)c1cnn(Cc3cccc(O)c3)c(=O)c1n2C CHEMBL1481562 Potency 65.1 nM
Cc1ccc(NS(=O)(=O)c2cc3c(cc2Cl)CCC(=O)N3)cc1C CHEMBL1939115 EC50 70.0 nM
Cc1cccc2nc(Cn3cnc4ccccc43)cc(=O)n12 CHEMBL2386917 EC50 70.0 nM
COc1cccc(Cn2ncc3c4sc([S+](C)[O-])cc4n(C)c3c2=O)c1 CHEMBL1085587 AC50 70.0 nM
COc1ccc(NC(=O)[C@@H]2[C@@H]3C(=O)N(C4CCCCC4)C(=O)[C@@H]3C3c4ccccc4C=CN32)cc1 CHEMBL1572997 Potency 70.8 nM
CCn1c2cc(C)sc2c2cnn(Cc3ccccc3F)c(=O)c21 CHEMBL1085411 Potency 70.8 nM
COc1ccc(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc4c(c3)OCCO4)CC2)cc1 CHEMBL1088762 Potency 80.0 nM
O=S(=O)(c1ccc2c(c1)OCCCO2)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1 CHEMBL1090756 Potency 80.0 nM
O=P(O)(O)OC[C@H]1O[C@@](O)(COP(=O)(O)O)[C@@H](O)[C@@H]1O CHEMBL1089962 Activity 80.0 nM
Cc1nc2cc(S(=O)(=O)N3CCN(S(=O)(=O)c4c(F)cccc4F)CC3)ccc2s1 CHEMBL1091056 AC50 86.0 nM
Cc1sc2nc(Cn3cnc4ccccc43)cc(=O)n2c1C CHEMBL2386923 AC50 86.0 nM
C=C1C(=O)O[C@H]2[C@H]1CC/C(COC(=O)c1ccc3nccc(Br)c3c1)=C/CC[C@@]1(C)O[C@@H]21 CHEMBL4875150 AC50 86.29 nM
COC(=O)c1cccc(NC(=O)Cc2coc3cc(OC)ccc23)c1 CHEMBL1564088 Potency 89.1 nM
CCNC(=O)COC(=O)c1sccc1C CHEMBL1393072 Potency 89.1 nM
O=C1CCC(=O)N1c1cccc(-c2nc3ccccc3o2)c1 CHEMBL1343252 Potency 89.1 nM
Cc1ccc(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc4c(c3)OCCO4)CC2)cc1 CHEMBL1598274 Potency 89.1 nM
O=C1CN(S(=O)(=O)c2c(F)cccc2F)CCN1S(=O)(=O)c1ccc2c(c1)OCCO2 CHEMBL1089059 Potency 89.7 nM
Cc1ccc(NS(=O)(=O)c2cc3c(cc2Cl)CCC(=O)N3)cc1Cl CHEMBL1939116 EC50 90.0 nM
O=C1CCc2cc(S(=O)(=O)Nc3ccc(F)c(Cl)c3)c(F)cc2N1 CHEMBL1939110 EC50 90.0 nM
Cc1ccc(NS(=O)(=O)c2cc3c(cc2C)NC(=O)CC3)cc1Cl CHEMBL5201754 EC50 90.0 nM
Cn1c2cc([S+](C)[O-])sc2c2cnn(Cc3cccc(N)c3)c(=O)c21 CHEMBL1085588 AC50 90.0 nM
O=C(c1cc(C2CC2)n[nH]1)N(Cc1ccc(O)cc1F)CC1CCC1 CHEMBL3104590 AC50 92.0 nM
Nc1cccc(S(=O)(=O)N2CCN(S(=O)(=O)c3c(F)cccc3F)CC2)c1 CHEMBL1091761 AC50 99.0 nM