CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL513909 IC50 0.083 nM
C[C@@H](Oc1cc(-n2cnc3ccc(CN4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1908394 Kd 0.094 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCOCC3)CC4)nc2N1C1CCCCC1 CHEMBL5417495 IC50 0.17 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4noc(CN5CCC(O)CC5)n4)cc3OC)nc2N1C1CCCC1 CHEMBL5423881 IC50 0.18 nM
CCOc1cc(C2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(Cc1cc(C)cs1)[C@H](CC)C(=O)N2C CHEMBL4449858 Kd 0.19 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CNC5CCC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5419732 IC50 0.19 nM
COc1ccc(CCNCc2ccc(OCc3ccc(Cl)nc3)c(OC)c2)cc1OC CHEMBL1625188 EC50 0.2 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CNC3CCCC3)CC4)nc2N1C1CCCC1 CHEMBL5416208 IC50 0.2 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CN(C)C)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5438707 IC50 0.23 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CN5CCC[C@H]5CO)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5433401 IC50 0.23 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4noc(CN5CCN(CCO)CC5)n4)cc3OC)nc2N1C1CCCC1 CHEMBL5415945 IC50 0.26 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCCCC3)CC4)nc2N1C1CCCC1 CHEMBL5426964 IC50 0.3 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCN(C)CC3)CC4)nc2N1C1CCCC1 CHEMBL5419367 IC50 0.3 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3C[C@@H](C)N[C@@H](C)C3)CC4)nc2N1C1CCCC1 CHEMBL5429440 IC50 0.3 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CNC3CC3)CC4)nc2N1C1CCCC1 CHEMBL5422122 IC50 0.3 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CNC5CCN(C)CC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5421113 IC50 0.3 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4noc(CN5CCCNCC5)n4)cc3OC)nc2N1C1CCCC1 CHEMBL5435085 IC50 0.32 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CN5CCNCC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5429110 IC50 0.33 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CN5CCN(C6CCCC6)CC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5438696 IC50 0.34 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4noc(CN5C[C@@H](C)N[C@@H](C)C5)n4)cc3OC)nc2N1C1CCCC1 CHEMBL5398211 IC50 0.37 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CNCC5CC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5396078 IC50 0.39 nM
CC[C@@H]1c2c(C#N)ncn2-c2cnc(Nc3cc(F)c(C(=O)NC4CCN(CC)CC4)cc3OC)nc2N1C(C)C CHEMBL4067710 IC50 0.4 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCC[C@H]3CO)CC4)nc2N1C1CCCC1 CHEMBL5427957 IC50 0.4 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CNC5CCCC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5437785 IC50 0.4 nM
CC[C@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL3609305 Ki 0.42 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCN(C(C)=O)CC3)CC4)nc2N1C1CCCCC1 CHEMBL5403473 IC50 0.42 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CN5CCOCC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5426743 IC50 0.42 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CN5CCCNCC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5402308 IC50 0.42 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)C(=O)N(C(C)C)C4)nc2N1C1CCCC1 CHEMBL5410968 IC50 0.43 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CN5CCN(CCO)CC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5394854 IC50 0.44 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4noc(CN5CCNCC5)n4)cc3OC)nc2N1C1CCCC1 CHEMBL5430344 IC50 0.45 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCCC3)CC4)nc2N1C1CCCC1 CHEMBL5403358 IC50 0.5 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCOCC3)CC4)nc2N1C1CCCC1 CHEMBL5418129 IC50 0.5 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCS(=O)(=O)CC3)CC4)nc2N1C1CCCC1 CHEMBL5395480 IC50 0.5 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCN(S(C)(=O)=O)CC3)CC4)nc2N1C1CCCC1 CHEMBL5401381 IC50 0.5 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CN5C[C@@H](C)N[C@@H](C)C5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5435649 IC50 0.5 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4noc(CN5CCC[C@H]5CO)n4)cc3OC)nc2N1C1CCCC1 CHEMBL5433215 IC50 0.5 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)C(=O)N(C3CCCC3)C4)nc2N1C1CCCC1 CHEMBL5412127 IC50 0.51 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)c(OC)c3)nc2N1C1CCCC1 CHEMBL3609310 Ki 0.52 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)C(=O)N(C3CCN(C)CC3)C4)nc2N1C1CCCC1 CHEMBL5421238 IC50 0.52 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CNC5CC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5430202 IC50 0.53 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CN5CCN(CC6CC6)CC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5416239 IC50 0.53 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4noc(CN(C)CCN(C)C)n4)cc3OC)nc2N1C1CCCC1 CHEMBL5426933 IC50 0.53 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CN5CCC(O)CC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5401755 IC50 0.55 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4noc(CN5CCN(CC)CC5)n4)cc3OC)nc2N1C1CCCC1 CHEMBL5440471 IC50 0.55 nM
COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CCC(=O)N2C CHEMBL2392552 Kd 0.57 nM
COC(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCC(N(C)C)CC3)cc2OC)ncc1[N+](=O)[O-] CHEMBL4790038 IC50 0.577 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCN(CCO)CC3)CC4)nc2N1C1CCCC1 CHEMBL5394764 IC50 0.6 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CN5CCCC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5434561 IC50 0.6 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CN5CCCCC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5395023 IC50 0.62 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4noc(CNC5CCN(C)CC5)n4)cc3OC)nc2N1C1CCCC1 CHEMBL5399905 IC50 0.62 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CN5CCN(CC)CC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5400707 IC50 0.63 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CN(C)CCN(C)C)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5439937 IC50 0.64 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc4c(c3)CN(C3CCN(C)CC3)C4=O)nc2N1C1CCCC1 CHEMBL5437669 IC50 0.65 nM
CCC(CC)NCc1nnc(-c2ccc(Nc3ncc4c(n3)N(C3CCCC3)[C@H](CC)C(=O)N4C)c(OC)c2)o1 CHEMBL5403446 IC50 0.69 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCC(O)CC3)CC4)nc2N1C1CCCC1 CHEMBL5428087 IC50 0.7 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCN(C(C)=O)CC3)CC4)nc2N1C1CCCC1 CHEMBL5438409 IC50 0.72 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4noc(CN5CCOCC5)n4)cc3OC)nc2N1C1CCCC1 CHEMBL5426079 IC50 0.76 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CN5CCN(C)CC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5412655 IC50 0.79 nM
COc1cc2ncn(-c3cc(O[C@H](C)c4ccccc4Cl)c(C(N)=O)s3)c2cc1OC CHEMBL222419 IC50 0.8 nM
COc1cc(C(=O)NC2CCN(C)CC2)c(F)cc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C CHEMBL2392545 IC50 0.8 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)N[C@H]4CC[C@H](N5CCN(CC6CC6)CC5)CC4)cc3OC)nc2N1C(C)C CHEMBL1233528 IC50 0.82 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC3CCCC3)nc2N1C1CCCC1 CHEMBL3609314 Ki 0.84 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)N[C@H]4CC[C@@H](N5CCN(CC6CC6)CC5)CC4)cc3OC)nc2N1C(C)C CHEMBL5276995 IC50 0.87 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN(CC)CC)CC4)nc2N1C1CCCC1 CHEMBL5409700 IC50 0.9 nM
CC[C@@H]1C(=O)N(CC)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL3609300 Ki 0.91 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4noc(CN5CCN(C)CC5)n4)cc3OC)nc2N1C1CCCC1 CHEMBL5405803 IC50 0.91 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCOCC3)CC4)nc2N1CC1CCCC1 CHEMBL5408776 IC50 0.94 nM
COc1ccc2ncn(-c3cc(O[C@H](C)c4ccccc4Cl)c(C(N)=O)s3)c2c1 CHEMBL493326 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OC[C@@H](O)CO)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1794067 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccncc4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209605 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccncc4)ccc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1209674 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4cccnc4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209676 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4cn[nH]c4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209759 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209841 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1209842 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(-c4cnn(C)c4)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1209843 IC50 1.0 nM
Cc1cc(-c2ccc3c(c2)ncn3-c2cc(O[C@H](C)c3ccccc3C(F)(F)F)c(C(N)=O)s2)ccn1 CHEMBL1209844 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(N)c4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1208835 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(N)n4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1208892 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4cnc(N)nc4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1208893 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(NCCS(C)(=O)=O)c4)ccc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1208962 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(NCCO)c4)ccc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1208963 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(NC5CCN(C)CC5)c4)ccc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1208964 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(NC5CCN(C)CC5)n4)ccc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1208966 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4cnn(CCN5CCOCC5)c4)ccc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1209015 IC50 1.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4cnn(CCN5CCN(C)CC5)c4)ccc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1209016 IC50 1.0 nM
CCN1CCN(CCCn2cc(-c3ccc4c(c3)ncn4-c3cc(O[C@H](C)c4ccccc4Cl)c(C(N)=O)s3)cn2)CC1 CHEMBL1209018 IC50 1.0 nM
CN(C)CCCc1cncc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)c1 CHEMBL1945803 IC50 1.0 nM
CN(C)CCCc1cc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)ccc1C(F)(F)F CHEMBL1945801 IC50 1.0 nM
COc1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)cc1CCCN(C)C CHEMBL1945502 IC50 1.0 nM
CN(C)CCCc1cc(Cl)cc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)c1 CHEMBL1945500 IC50 1.0 nM
CN(C)CCCc1ccc(Cl)c(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)c1 CHEMBL1945172 IC50 1.0 nM
COc1cc(C(=O)NC2CCN(C)CC2)c(Cl)cc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C CHEMBL2392549 IC50 1.0 nM
CN1CCC(NC(=O)c2ccc(Nc3ncc4c(n3)N(C3CCCC3)CC(F)(F)C(=O)N4C)cc2)CC1 CHEMBL2392548 IC50 1.0 nM
C=CC[C@H]1CN(C2CCCC2)c2nc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)ncc2N(C)C1=O CHEMBL2392556 IC50 1.0 nM
C=Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCN(C)CC4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1793896 IC50 1.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 CHEMBL1272140 IC50 1.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCSCC3)CC4)nc2N1C1CCCC1 CHEMBL5398977 IC50 1.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4noc(CN(C)C)n4)cc3OC)nc2N1C1CCCC1 CHEMBL5423798 IC50 1.02 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4nnc(CN5CCC(F)(F)CC5)o4)cc3OC)nc2N1C1CCCC1 CHEMBL5404388 IC50 1.07 nM
COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)[C@H](C)C(=O)N2C CHEMBL4209902 IC50 1.1 nM
COC(=O)c1sccc1Nc1nc(Nc2ccc(N3CCC(O)CC3)cc2)ncc1[N+](=O)[O-] CHEMBL4783888 IC50 1.27 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCOCC3)CC4)nc2N1C1CCOCC1 CHEMBL5421723 IC50 1.27 nM
CC[C@@H]1c2c(C#N)ncn2-c2cnc(Nc3cc(F)c(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCCC1 CHEMBL4078098 IC50 1.3 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCOCC3)CC4)nc2N1Cc1cccs1 CHEMBL5409453 IC50 1.34 nM
COC(=O)c1sccc1Nc1nc(Nc2ccc(N3CCC(N(C)C)CC3)cc2OC)ncc1Br CHEMBL4780169 IC50 1.39 nM
CC[C@@H]1c2c(C(=O)O)ncn2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL4094634 IC50 1.4 nM
CC[C@@H]1c2c(C#N)ncn2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL4074778 IC50 1.5 nM
COC(=O)c1sccc1Nc1nc(Nc2ccc(N3CCC(N4CCCC4)CC3)cc2OC)ncc1[N+](=O)[O-] CHEMBL4795375 IC50 1.58 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCSCC3)nc2N1C1CCCC1 CHEMBL5440739 IC50 1.6 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCN(C(C)=O)CC3)nc2N1CC1CCCC1 CHEMBL5405036 IC50 1.6 nM
CC[C@@H]1c2c(C#N)ncn2-c2cnc(Nc3cc(F)c(C(=O)NC4CN(C)C4)cc3OC)nc2N1C(C)C CHEMBL4088932 IC50 1.7 nM
COC(=O)c1sccc1Nc1nc(Nc2ccc(N3CCC(N(C)C)CC3)cc2OC)ncc1C CHEMBL4799529 IC50 1.85 nM
CC[C@@H]1c2c(C#N)ncn2-c2cnc(Nc3cc(F)c(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C(C)C CHEMBL4103908 IC50 1.9 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCN(C(C)=O)CC3)CC4)nc2N1CC1CCCCC1 CHEMBL5406467 IC50 1.98 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(N)=O)s3)c2cc1OC CHEMBL514499 IC50 2.0 nM
COc1cc2ncn(-c3cc(OCc4ccccc4Cl)c(C(N)=O)s3)c2cc1OC CHEMBL514162 IC50 2.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OC4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1615278 IC50 2.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OC4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1794070 IC50 2.0 nM
COc1ccc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(N)=O)s3)c2c1 CHEMBL474843 IC50 2.0 nM
COc1cc2ncn(-c3cc(OCc4ccccc4Br)c(C(N)=O)s3)c2cc1OC CHEMBL474028 IC50 2.0 nM
COc1cc2ncn(-c3cc(OCc4sccc4Cl)c(C(N)=O)s3)c2cc1OC CHEMBL480545 IC50 2.0 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(=O)O)s3)c2cc1OC CHEMBL474432 IC50 2.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(-c4ccncc4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209606 IC50 2.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(-c4ccncc4)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1209675 IC50 2.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(-c4cccnc4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209677 IC50 2.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(N5CCN(C)CC5)c4)ccc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1208958 IC50 2.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccc(NC5CCN(C)CC5)nc4)ccc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1208965 IC50 2.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4cnn(CCCN(C)C)c4)ccc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1209017 IC50 2.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCNCC4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1271644 IC50 2.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3CCO)CC4)c2)CC1 CHEMBL1738758 IC50 2.0 nM
Cc1ncc(CCCN(C)C)cc1Nc1ncc2c(n1)-c1ccc(C(F)(F)F)cc1NC(=S)C2 CHEMBL1945805 IC50 2.0 nM
Cc1ncc(CCCN(C)C)cc1Nc1ncc2c(n1)-c1ccc(Cl)cc1NC(=S)C2 CHEMBL1945804 IC50 2.0 nM
CN(C)CCCc1cc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)ccc1F CHEMBL1945501 IC50 2.0 nM
Cc1ccc(CCCN(C)C)cc1Nc1ncc2c(n1)-c1ccc(Cl)cc1NC(=S)C2 CHEMBL1945171 IC50 2.0 nM
CC[C@@]1(F)CN(C2CCCC2)c2nc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)ncc2N(C)C1=O CHEMBL2392554 IC50 2.0 nM
CC[C@@H]1c2c(C(N)=O)ncn2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL4063398 IC50 2.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCOCC3)CC4)nc2N1CC1CCCCC1 CHEMBL5415796 IC50 2.09 nM
CCOC(=O)c1ncn2c1[C@@H](CC)N(C1CCCC1)c1nc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)ncc1-2 CHEMBL4074112 IC50 2.1 nM
CC[C@@H]1c2c(CO)ncn2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL4101459 IC50 2.2 nM
CC[C@@H]1c2c(C#N)ncn2-c2cnc(Nc3cc(F)c(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL4066163 IC50 2.2 nM
COc1cc2ncn(-c3cc(-c4cccc(C(F)(F)F)c4)c(C(N)=O)s3)c2cc1OC CHEMBL5190855 pIC50 2.2 nM
COC(=O)c1sccc1Nc1nc(Nc2ccc(N3CCC(N4CCCC4)CC3)cc2OC)ncc1C CHEMBL4776291 IC50 2.22 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCOCC3)nc2N1C1CCCC1 CHEMBL5428017 IC50 2.3 nM
COC(=O)c1sccc1Nc1nc(Nc2ccc(N3CCC(N(C)C)CC3)cc2OC)ncc1C#N CHEMBL4784741 IC50 2.67 nM
COc1ccc2ncn(-c3cc(O[C@H](C)c4ccccc4C(F)(F)F)c(C(N)=O)s3)c2c1 CHEMBL522709 IC50 3.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OC[C@H](O)CN4CCCC4)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1964262 IC50 3.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OC4CCNCC4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1964263 IC50 3.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(O[C@H]4CCCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1964264 IC50 3.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4cccs4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209757 IC50 3.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(N5CCN(C)CC5)c4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1208959 IC50 3.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(NCCN(C)C)c4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1208961 IC50 3.0 nM
CN1CC=C(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 CHEMBL1774327 IC50 3.0 nM
C=C[C@@]1(F)CN(C2CCCC2)c2nc(Nc3ccc(C(=O)NN4CCN(C)CC4)cc3OC)ncc2N(C)C1=O CHEMBL2392544 IC50 3.0 nM
COc1cc(CNCc2ccncc2)ccc1OCc1ccc(Cl)cc1 CHEMBL3344193 IC50 3.0 nM
C=CCn1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2n1-c1cccc(C(C)(C)O)n1 CHEMBL1976040 Kd 3.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCN(C(C)=O)CC3)nc2N1C1CCCC1 CHEMBL5402922 IC50 3.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCN(C(C)=O)CC3)CC4)nc2N1Cc1cccs1 CHEMBL5437723 IC50 3.12 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCC[C@H]3CO)nc2N1C1CCCC1 CHEMBL5402431 IC50 3.3 nM
COC(=O)c1sccc1Nc1nc(Nc2ccc(N3CCC(N4CCCC4)CC3)cc2OC)ncc1C(F)(F)F CHEMBL4785567 IC50 3.31 nM
COC(=O)c1sccc1Nc1nc(Nc2ccc(N3CCC(N4CCCC4)CC3)cc2OC)ncc1Br CHEMBL4790028 IC50 3.44 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NC4CCN(C)CC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4459892 IC50 3.58 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCN(C)CC3)nc2N1C1CCCC1 CHEMBL5415794 IC50 3.6 nM
COC(=O)c1ccsc1Nc1nc(Nc2ccc(N3CCN(C)CC3)cc2OC)ncc1[N+](=O)[O-] CHEMBL4784781 IC50 3.69 nM
COC(=O)c1sccc1Nc1nc(Nc2ccc(N3CCC(N4CCCC4)CC3)cc2OC)ncc1C#N CHEMBL4779654 IC50 3.82 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NC4CCCC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4458460 IC50 3.89 nM
CC[C@@H]1c2c(C#N)ncn2-c2cnc(Nc3cc(F)c(C(=O)N[C@H]4CC[C@H](N5CCN(CC6CC6)CC5)CC4)cc3OC)nc2N1C(C)C CHEMBL4096151 IC50 3.9 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OCCCN(C)C)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1964261 IC50 4.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(O[C@@H]4CCCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1964265 IC50 4.0 nM
Cc1ccccc1COc1cc(-n2cnc3ccc(Cl)cc32)sc1C(N)=O CHEMBL519120 IC50 4.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(Cl)c4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1208833 IC50 4.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3[nH]nc(C(N)=O)c3CC4)c2)CC1 CHEMBL1793891 IC50 4.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3CCF)CC4)c2)CC1 CHEMBL1793892 IC50 4.0 nM
CN(C)CCCc1ccc(C(F)(F)F)c(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)c1 CHEMBL1945498 IC50 4.0 nM
CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc4c(c3)Cc3ccccc3-4)n2)c(=O)c1=O CHEMBL2205458 Ki 4.0 nM
COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C CHEMBL2392553 IC50 4.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C(C)C CHEMBL4207165 IC50 4.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCCC1 CHEMBL4215729 IC50 4.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL2207845 IC50 4.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCCCC3)nc2N1C1CCCC1 CHEMBL5395241 IC50 4.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCN(S(C)(=O)=O)CC3)nc2N1C1CCCC1 CHEMBL5417454 IC50 4.1 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCN(C(C)=O)CC3)nc2N1Cc1cccs1 CHEMBL5430428 IC50 4.1 nM
COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)[C@H](Cc1ccccc1)C(=O)N2Cc1ccccc1 CHEMBL3609306 Ki 4.2 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4450624 IC50 4.27 nM
COC(=O)c1sccc1Nc1nc(Nc2cc3c(cc2OC)CCN3C(=O)CN(C)C)ncc1Br CHEMBL4800085 IC50 4.28 nM
COC(=O)c1sccc1Nc1nc(Nc2ccc(N3CCN(C)CC3)cc2)ncc1[N+](=O)[O-] CHEMBL4800017 IC50 4.37 nM
COC(=O)c1sccc1Nc1nc(Nc2ccc(N3CCC(N(C)C)CC3)cc2OC)ncc1C(F)(F)F CHEMBL4783122 IC50 4.55 nM
COC(=O)c1sccc1Nc1nc(Nc2ccc(N3CCN(C)CC3)cc2OC)ncc1[N+](=O)[O-] CHEMBL4787496 IC50 4.67 nM
COC(=O)c1sccc1Nc1nc(Nc2cc3c(cc2OC)CCN3C(=O)CN(C)C)ncc1C CHEMBL4778470 IC50 4.72 nM
COC(=O)c1sccc1Nc1nc(Nc2cc3c(cc2OC)CCN3C(=O)CN(C)C)ncc1C#N CHEMBL4778422 IC50 4.87 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CO)cc1Cl CHEMBL560488 IC50 4.9 nM
COC(=O)c1ccsc1Nc1nc(Nc2ccc(N3CCN(C)CC3)cc2)ncc1[N+](=O)[O-] CHEMBL4796797 IC50 4.99 nM
COc1cc2ncn(-c3cc(OCc4ccccc4OC(F)(F)F)c(C(N)=O)s3)c2cc1OC CHEMBL474053 IC50 5.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccc[nH]4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209758 IC50 5.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(N5CCOCC5)c4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1208960 IC50 5.0 nM
CN(C)CCCc1cccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)c1 CHEMBL1945170 IC50 5.0 nM
CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4ccncc4)cc3)n2)c(=O)c1=O CHEMBL2205426 Ki 5.0 nM
C=C[C@@]1(F)CN(C2CCCC2)c2nc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)ncc2N(C)C1=O CHEMBL2392558 IC50 5.0 nM
Cc1ccc(N2CCN(C)CC2)cc1Nc1ncc2c(n1)-c1c(c(C(=O)O)nn1C)CC2 CHEMBL3652222 IC50 5.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1Cc2c[n+](cn2CCCCCCCCc2ccccc2)CCCCCCNC(=O)[C@H]([C@@H](C)OP(=O)(O)O)NC(=O)[C@H](CO)NC1=O CHEMBL4278200 IC50 5.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1C[C@H](CCCCCCCCc2ccccc2)C(=O)NCCC[C@@H](C(N)=O)NC(=O)[C@H]([C@@H](C)OP(=O)(O)O)NC(=O)[C@H](CO)NC1=O CHEMBL5179633 IC50 5.0 nM
COC(=O)c1ccsc1Nc1nc(Nc2cc3c(cc2OC)CCN3C(=O)CN(C)C)ncc1[N+](=O)[O-] CHEMBL4799183 IC50 5.13 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NC4CCOCC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4441121 IC50 5.14 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCC(O)CC3)nc2N1C1CCCC1 CHEMBL5408013 IC50 5.2 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCN(C4CCCC4)CC3)nc2N1C1CCCC1 CHEMBL5410310 IC50 5.2 nM
COC(=O)c1ccsc1Nc1nc(Nc2ccc(N3CCC(N4CCCC4)CC3)cc2OC)ncc1[N+](=O)[O-] CHEMBL4790807 IC50 5.26 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCN(C(C)C)CC3)nc2N1C1CCCC1 CHEMBL5437467 IC50 5.3 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1c(F)cccc1Oc1cccc(O)c1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL4068949 IC50 5.5 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1ccc(CCO)cc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL4092848 IC50 5.5 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCCC4)cc3C)nc2N1C1CCCC1 CHEMBL4454222 IC50 5.75 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(C)=O)cc3OCCO)nc2N1C1CCCC1 CHEMBL4447251 IC50 5.76 nM
COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O CHEMBL428496 IC50 5.8 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1Cc1cccc(Br)c1 CHEMBL3609308 Ki 5.8 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCCC4)cc3O)nc2N1C1CCCC1 CHEMBL4548940 IC50 5.89 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OCC4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1794069 IC50 6.0 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C#N)c(C(N)=O)s3)c2cc1OC CHEMBL474029 IC50 6.0 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(N)=S)s3)c2cc1OC CHEMBL482151 IC50 6.0 nM
NC(=O)c1nn(CC(F)(F)F)c2c1CCc1cnc(Nc3ccccc3)nc1-2 CHEMBL1095709 IC50 6.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccccc4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209603 IC50 6.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccccn4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209756 IC50 6.0 nM
CCn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCN(C)CC4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1793893 IC50 6.0 nM
CN1CCC(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)cn3C)CC4)c2)CC1 CHEMBL1774328 IC50 6.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1Cc2c[n+](cn2CCCCCCCCc2ccccc2)CCCCCNC(=O)[C@H]([C@@H](C)OP(=O)(O)O)NC(=O)[C@H](CO)NC1=O CHEMBL4281659 IC50 6.0 nM
COC(=O)c1sccc1Nc1nc(Nc2cc3c(cc2OC)CCN3C(=O)CN(C)C)ncc1[N+](=O)[O-] CHEMBL4776345 IC50 6.19 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(S(=O)(=O)CC(=O)N4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL5413543 IC50 6.3 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCCC(C)C3)nc2N1C1CCCC1 CHEMBL5402704 IC50 6.5 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1c(F)cccc1Oc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL3956625 IC50 6.6 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC(C)C)cc3OCCO)nc2N1C1CCCC1 CHEMBL4448563 IC50 6.86 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1CC(C)C CHEMBL3609307 Ki 6.95 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OCC4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1794068 IC50 7.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccccc1Cl CHEMBL560014 IC50 7.0 nM
COc1ccc(N2CCN(C)CC2)cc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1094408 IC50 7.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3CCCl)CC4)c2)CC1 CHEMBL1793895 IC50 7.0 nM
CN(C)CCCc1ccc(OC(F)(F)F)c(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)c1 CHEMBL1945497 IC50 7.0 nM
COc1ccc(CO)cc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL3652224 IC50 7.0 nM
CC[C@@H]1c2c(C(=O)N(C)O)ncn2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL4093737 IC50 7.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NC(C)C)cc3OCCO)nc2N1C1CCCC1 CHEMBL4457656 IC50 7.2 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3C[C@@H](C)N[C@@H](C)C3)nc2N1C1CCCC1 CHEMBL5412529 IC50 7.2 nM
CCC1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NC4CCCC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4465062 IC50 7.28 nM
C[C@@H](Oc1cc(-c2cnc3ccc(CO)cn23)sc1C(N)=O)c1ccccc1Cl CHEMBL563447 IC50 7.3 nM
COC(=O)c1ccsc1Nc1nc(Nc2ccc(N3CCC(N(C)C)CC3)cc2OC)ncc1[N+](=O)[O-] CHEMBL4781522 IC50 7.35 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN(CC)CC)nc2N1C1CCCC1 CHEMBL5434467 IC50 7.8 nM
CCC1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCCCC4)cc3OC)nc2N1C1CCCC1 CHEMBL2005375 pKi 7.943 nM
CCNC(=O)c1cc(OCCO)c(Nc2ncc3c(n2)N(C2CCCC2)[C@H](CC)C(=O)N3C)cc1F CHEMBL4570557 IC50 7.99 nM
COc1ccc2c(c1)ncn2-c1cc(OCc2ccccc2C(F)(F)F)c(C(N)=O)s1 CHEMBL514968 IC50 8.0 nM
COc1ccccc1COc1cc(-n2cnc3cc(OC)c(OC)cc32)sc1C(N)=O CHEMBL474054 IC50 8.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(N5CCNCC5)c4)ccc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1208894 IC50 8.0 nM
CCN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 CHEMBL1271590 IC50 8.0 nM
CC(C)c1ccc(CCCN(C)C)cc1Nc1ncc2c(n1)-c1ccc(Cl)cc1NC(=S)C2 CHEMBL1945499 IC50 8.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccccc3)nc2N1C1CCCC1 CHEMBL2401963 IC50 8.0 nM
COc1cc(N2CCN(CCO)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CCC(=O)N2C CHEMBL3929934 Kd 8.0 nM
CC(=O)N[C@H]1Cc2c[n+](cn2CCCCCCCCc2ccccc2)CCCCCNC(=O)[C@H]([C@@H](C)OP(=O)(O)O)NC(=O)[C@H](CO)NC1=O CHEMBL4287557 IC50 8.0 nM
COC(=O)c1sccc1Nc1nc(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)cc2OC)ncc1[N+](=O)[O-] CHEMBL4783750 IC50 8.13 nM
COc1cc(C(=O)NC2=CCN(C)C=C2)ccc1Nc1ncc2c(n1)N(C1CCCC1)[C@H](C)C(=O)N2C CHEMBL4216442 IC50 8.4 nM
CC[C@@H]1c2c(C#N)ncn2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C(C)C CHEMBL4085987 IC50 8.6 nM
COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCCC1)[C@H](C)C(=O)N2C CHEMBL4202820 IC50 8.6 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCC(C)CC3)nc2N1C1CCCC1 CHEMBL5418320 IC50 8.6 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCN(CC)CC3)nc2N1C1CCCC1 CHEMBL5422930 IC50 8.6 nM
COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)[C@@H](C)C(=O)N2C CHEMBL4216875 IC50 8.7 nM
CC(=O)N1CCN(c2ccc(Nc3ncc(C(F)(F)F)c(N4Cc5cccc(N(C)S(C)(=O)=O)c5C4)n3)cc2)CC1 CHEMBL4476226 IC50 8.8 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCN(CCO)CC3)nc2N1C1CCCC1 CHEMBL5417441 IC50 8.8 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCCC3)nc2N1C1CCCC1 CHEMBL5408583 IC50 8.9 nM
NC(=O)c1sc(-n2cnc3ccc(C(F)(F)F)cc32)cc1OCc1ccccc1Br CHEMBL481510 IC50 9.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3nccc(-c4cc5c(n4C)CCNC5=O)n3)c2)CC1 CHEMBL1933582 IC50 9.0 nM
COc1cc(OC)c(/C=C/S(=O)(=O)Cc2ccc(OC)c(NCC(=O)O)c2)c(OC)c1 CHEMBL1241855 IC50 9.0 nM
COc1cc(C(=O)NC2CCNCC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)[C@H](C)C(=O)N2C CHEMBL4213276 IC50 9.0 nM
CC(C)(O)c1cccc(-n2cc(F)c3cnc(Nc4ccc(C(=O)NC5CCOCC5)cc4)nc32)n1 CHEMBL4860427 IC50 9.0 nM
COc1cc(OC)c(/C=C/S(=O)(=O)Cc2ccc(OC)c(NCC(=O)[O-])c2)c(OC)c1 CHEMBL2013119 IC50 9.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCCC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4531932 IC50 9.31 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCOCC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4519294 IC50 9.42 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1ccc(CCOCc2ccccc2)cc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL4065187 IC50 9.7 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CNC(C)(C)C)cc1OC(F)F CHEMBL551079 IC50 9.8 nM
CCC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL4206171 IC50 9.9 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL4456099 IC50 9.9 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NC)cc3OCCO)nc2N1C1CCCC1 CHEMBL4456400 IC50 9.97 nM
COc1ccc(CCCN(C)C)cc1Nc1ncc2c(n1)-c1ccc(Cl)cc1NC(=S)C2 CHEMBL1945173 IC50 10.0 nM
COc1ccc(Nc2ncc3c(n2)-c2ccc(I)cc2NC(=O)C3)cc1OC CHEMBL1947149 IC50 10.0 nM
CS(=O)(=O)N(Cc1ccc2[nH]c(=O)c3cccn3c2c1)C1CC1 CHEMBL1978448 pKi 10.0 nM
CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4cn[nH]c4)cc3)n2)c(=O)c1=O CHEMBL2205423 Ki 10.0 nM
CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc4c(c3)[nH]c3ccccc34)n2)c(=O)c1=O CHEMBL2205462 Ki 10.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(=O)O)nn3C)CC4)c2)CC1 CHEMBL3652219 IC50 10.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1Cc2c[n+](cn2CCCCCCCCc2ccccc2)CCCCNC(=O)[C@H]([C@@H](C)OP(=O)(O)O)NC(=O)[C@H](CO)NC1=O CHEMBL4292295 IC50 10.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCCC4)cc3CCO)nc2N1C1CCCC1 CHEMBL4436925 IC50 10.17 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NCCN4CCN(C)CC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4447495 IC50 10.17 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCN(C(C)=O)CC3)nc2N1Cc1cc(C)cs1 CHEMBL5426693 IC50 10.4 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)N(C(=O)CN3CCOCC3)CC4)nc2N1Cc1ccccc1 CHEMBL5400502 IC50 10.9 nM
NC(=O)c1sc(-n2cnc3ccccc32)cc1OCc1ccccc1Br CHEMBL518953 IC50 11.0 nM
COc1cc2ncn(-c3cc(OCc4cccs4)c(C(N)=O)s3)c2cc1OC CHEMBL480382 IC50 11.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1c(F)cccc1Oc1cccc(OCc2ccccc2)c1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL4080819 IC50 11.2 nM
Cc1ccccc1COc1cc(-n2cnc3ccccc32)sc1C(N)=O CHEMBL518956 IC50 12.0 nM
Cc1cccc(COc2cc(-n3cnc4ccccc43)sc2C(N)=O)c1 CHEMBL449608 IC50 12.0 nM
COc1ccccc1COc1cc(-n2cnc3ccccc32)sc1C(N)=O CHEMBL475597 IC50 12.0 nM
NC(=O)c1sc(-n2cnc3ccccc32)cc1OCc1ccccc1Cl CHEMBL474603 IC50 12.0 nM
CS(=O)(=O)c1ccc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(N)=O)s3)c2c1 CHEMBL514826 IC50 12.0 nM
COc1cc2ncn(-c3cc(OCc4ccccc4)c(C(N)=O)s3)c2cc1OC CHEMBL475857 IC50 12.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CNC2CC2)cc1Cl CHEMBL561286 IC50 12.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CN2CCNC(=O)C2)cc1Cl CHEMBL550475 IC50 12.0 nM
O=C1Cc2cnc(Nc3ccc(C(=O)NC4CCCC4)cc3)nc2-c2ccc(Cl)cc2N1 CHEMBL1945026 IC50 12.0 nM
COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC CHEMBL1241473 Ki 12.0 nM
CCOc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)[C@H](CC)C(=O)N2C CHEMBL4464826 IC50 12.0 nM
CCN1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL1967560 pKi 12.59 nM
COc1ccc(COc2cc(-n3cnc4cc(OC)c(OC)cc43)sc2C(N)=O)cc1 CHEMBL514643 IC50 13.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CN2CCC(F)CC2)cc1Cl CHEMBL563469 IC50 13.0 nM
CCC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4ccccc4)cc3)n2)c(=O)c1=O CHEMBL2205456 Ki 13.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCCC4)cc3OC)nc2N1C1CCCC1 CHEMBL4592698 IC50 13.97 nM
NC(=O)c1sc(-n2cnc3ccccc32)cc1OCc1ccccc1F CHEMBL508763 IC50 14.0 nM
COc1cc2ncn(-c3cc(OCc4ccnc(Br)c4)c(C(N)=O)s3)c2cc1OC CHEMBL475763 IC50 14.0 nM
CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4ccccc4)cc3)n2)c(=O)c1=O CHEMBL2205457 Ki 14.0 nM
Cc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1094477 IC50 14.0 nM
CC(=O)N1C[C@H](OCCCCc2ccccc2)C[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL5185686 IC50 14.0 nM
NC(=O)c1sc(-n2cnc3ccccc32)cc1OCc1ccccc1C(F)(F)F CHEMBL481491 IC50 15.0 nM
COCCn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCN(C)CC4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1793894 IC50 15.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3nccc(-c4cc(C(N)=O)cn4C)n3)c2)CC1 CHEMBL1933576 IC50 15.0 nM
CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4csnn4)cc3)n2)c(=O)c1=O CHEMBL2205461 Ki 15.0 nM
COc1cc(Nc2ncc3c(n2)N(C2CCCC2)CC(F)(F)C(=O)N3C)ccc1C(=O)NC1CCN(C)CC1 CHEMBL2392550 IC50 15.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC)cc3OCCO)nc2N1C1CCCC1 CHEMBL4566834 IC50 15.66 nM
CNCc1ccc([C@@H](C)Oc2cc(-c3cnc4ccccn34)sc2C(N)=O)c(Cl)c1 CHEMBL555970 IC50 16.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CN2CCS(=O)(=O)CC2)cc1Cl CHEMBL552348 IC50 16.0 nM
C=CCn1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)c4ccn(C)c34)nc2n1-c1cccc(C(C)(C)O)n1 CHEMBL5272327 IC50 16.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(S(=O)(=O)NC)cc3)nc2N1C1CCCC1 CHEMBL4166771 IC50 16.05 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C(C)=O)c(C(N)=O)s3)c2cc1OC CHEMBL514634 IC50 17.0 nM
COc1cc2ncn(-c3cc(OCC4CCCCC4)c(C(N)=O)s3)c2cc1OC CHEMBL520080 IC50 17.0 nM
COc1cc2ncn(-c3cc(OCc4ccsc4)c(C(N)=O)s3)c2cc1OC CHEMBL480383 IC50 17.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CN2CCN(C)CC2)cc1Cl CHEMBL557126 IC50 17.0 nM
CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc4[nH]ncc4c3)n2)c(=O)c1=O CHEMBL2205466 Ki 17.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cn(CCCCCCCCc2ccccc2)nn1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL5196402 IC50 17.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C(C)C)CC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4515187 IC50 17.29 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NCCN4CCOCC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4529398 IC50 17.9 nM
C[C@@H](Oc1cc(-n2cnc3ccc(-c4ccccc4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209604 IC50 18.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3nccc(-c4cc(C(N)=O)cn4CC(F)(F)F)n3)c2)CC1 CHEMBL1933577 IC50 18.0 nM
Cn1cc(C(N)=O)cc1-c1ccnc(Nc2cc(N3CCNCC3)ccc2OC(F)(F)F)n1 CHEMBL1933578 IC50 18.0 nM
COc1ccc(Nc2ncc3c(n2)-c2ccc(C(F)(F)F)cc2NC(=O)C3)cc1OC CHEMBL1944678 IC50 18.0 nM
CN1C(=O)[C@H]2CCC[C@H]2N(C2CCCC2)c2nc(Nc3ccc(C(N)=O)cc3)ncc21 CHEMBL3986079 Kd 18.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CNCCCO)cc1Cl CHEMBL552084 IC50 19.0 nM
COc1cc(N2CCC(O)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CCC(=O)N2C CHEMBL1230645 Kd 19.0 nM
CC(C)(O)c1cccc(-n2cc(F)c3cnc(Nc4ccc(N5C[C@H]6C[C@@H]5CN6)cc4)nc32)n1 CHEMBL4871955 IC50 19.0 nM
CCn1c(=O)/c(=C/Nc2cccc(CCN3CCCC3)c2)s/c1=C(\C#N)C(=O)NC(F)(F)F CHEMBL5281562 IC50 19.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CN2CCC(O)C2)cc1Cl CHEMBL562735 IC50 20.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CNC(C)(C)C)cc1C(F)F CHEMBL551078 IC50 20.0 nM
NC(=O)c1sc2c([N+](=O)[O-])cc(SC(F)(F)F)cc2[n+]1[O-] CHEMBL1222044 IC50 20.0 nM
COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL509032 Kd 20.0 nM
CC(=O)N1CCc2cc(Nc3nccc(Nc4c(NC(C)(C)C)c(=O)c4=O)n3)ccc21 CHEMBL2205422 Ki 20.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NCCN4CCOCC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4573833 IC50 20.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(N)=O)cc3OCCO)nc2N1C1CCCC1 CHEMBL4461041 IC50 20.72 nM
Cc1nn(-c2cc(Cl)cc(CCC(=O)O)c2)c2cc(N[C@@H](C)c3ccccc3)ncc12 CHEMBL484473 IC50 21.0 nM
Cc1ccccc1COc1cc(-n2cnc3cc(Cl)ccc32)sc1C(N)=O CHEMBL481492 IC50 21.0 nM
COc1cc2ncn(-c3cc(OCc4cccc(N)c4)c(C(N)=O)s3)c2cc1OC CHEMBL475783 IC50 21.0 nM
CCNCc1ccc([C@@H](C)Oc2cc(-c3cnc4ccccn34)sc2C(N)=O)c(Cl)c1 CHEMBL551483 IC50 21.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CNC(C)(C)C)cc1Cl CHEMBL551545 IC50 21.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CNCCO)cc1Cl CHEMBL563363 IC50 21.0 nM
NC(=O)c1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=O)C3)cc1 CHEMBL1945025 IC50 21.0 nM
CN1CC[C@@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@@H]1CO CHEMBL3991935 Kd apparent 21.0 nM
COc1cc(C(=O)NCCN(C)C)ccc1Nc1ncc2c(n1)N(C1CCCC1)[C@H](C)C(=O)N2C CHEMBL4210571 IC50 21.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NCCN4CCN(C)CC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4576641 IC50 21.21 nM
CCNC(=O)c1ccc(Nc2ncc3c(n2)N(C2CCCC2)[C@H](CC)C(=O)N3C)c(OCCO)c1 CHEMBL4545446 IC50 21.38 nM
NC(=O)c1sc(-n2cnc3ccccc32)cc1OCc1cccc(Cl)c1 CHEMBL445277 IC50 22.0 nM
NC(=O)c1sc(-c2cnc3ccccn23)cc1OCc1ccccc1C(F)(F)F CHEMBL564431 IC50 22.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CN(C)C)cc1Cl CHEMBL563387 IC50 22.0 nM
CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc4c(c3)CCO4)n2)c(=O)c1=O CHEMBL2205465 Ki 22.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1CC1CCCCC1 CHEMBL4747491 IC50 22.0 nM
C=CCOC(=O)/C(C#N)=C1\S[C@@H](CNc2ccc(NC(=O)NCCN3CCCC3)cc2)C(=O)N1CC CHEMBL477407 IC50 23.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CNC(C)(C)CO)cc1Cl CHEMBL563411 IC50 23.0 nM
CN1CCN(c2ccc(Nc3ncc4c(F)cn(-c5cccc(C6(F)COC6)n5)c4n3)cc2)CC1 CHEMBL4852679 IC50 24.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(S(=O)(=O)NCCO)cc3)nc2N1C1CCCC1 CHEMBL4176983 IC50 24.76 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CNC2CCCC2)cc1Cl CHEMBL564529 IC50 25.0 nM
CN1CCCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 CHEMBL1272195 IC50 25.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCc1cn(Cc2ccc(Oc3ccccc3)cc2F)nn1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL5170038 IC50 25.0 nM
COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C(C)C)[C@H](C)C(=O)N2C CHEMBL4206052 IC50 25.2 nM
COc1c(Nc2ncc3c(n2)N(C2CCCC2)CC(F)(F)C(=O)N3C)ccc(C(=O)NC2CCN(C)CC2)c1F CHEMBL2392547 IC50 26.0 nM
NC(=O)c1nn(CCF)c2c1CCc1cnc(Nc3ccccc3OC(F)(F)F)nc1-2 CHEMBL3652221 IC50 26.0 nM
CNC(=O)c1nn(C)c2c1CCc1cnc(Nc3cc(N4CCN(C)CC4)ccc3OC)nc1-2 CHEMBL3652220 IC50 26.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NC4CCN(C)CC4)cc3OCCO)nc2N1C(C)C CHEMBL4442768 IC50 26.77 nM
COc1cc2ncn(-c3cc(OCc4ccco4)c(C(N)=O)s3)c2cc1OC CHEMBL482349 IC50 27.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CN2CCC(O)CC2)cc1Cl CHEMBL564067 IC50 27.0 nM
COc1cc(C(=O)NCCc2ccccc2)ccc1Nc1ncc2c(n1)N(C1CCCC1)[C@H](C)C(=O)N2C CHEMBL4203571 IC50 27.0 nM
COc1cccc(COc2cc(-n3cnc4ccccc43)sc2C(N)=O)c1 CHEMBL516248 IC50 28.0 nM
CC(C)NCc1ccc([C@@H](C)Oc2cc(-c3cnc4ccccn34)sc2C(N)=O)c(Cl)c1 CHEMBL560808 IC50 28.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3nccc(-c4cc5c(n4CC(F)(F)F)CCNC5=O)n3)c2)CC1 CHEMBL1933583 IC50 28.0 nM
CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4cccnc4)cc3)n2)c(=O)c1=O CHEMBL2205425 Ki 28.0 nM
CN1CCC(NC(=O)c2ccc(Nc3ncc4c(F)cn(-c5cccc(C(C)(C)O)n5)c4n3)cc2)CC1 CHEMBL4863747 IC50 29.0 nM
COC(=O)c1sccc1Nc1nc(Nc2cc3c(cc2OC)CCN3C(=O)CN(C)C)ncc1F CHEMBL4793797 IC50 29.3 nM
COc1cc2ncn(-c3cc(O[C@@H](C)c4ccccc4Cl)c(C(N)=O)s3)c2cc1OC CHEMBL521806 IC50 30.0 nM
COc1cc(Nc2ncc3c(C)nc(-c4cccc(C(F)(F)F)c4)n3n2)cc(OC)c1OC CHEMBL520037 IC50 30.0 nM
COc1cccc(/C=C/C(=O)NNC(=O)c2ccc3c(c2)OCCO3)c1 CHEMBL3260241 IC50 30.0 nM
CC(C)(O)c1cccc(-n2cc(F)c3cnc(Nc4ccc(NC(=O)C5CCOCC5)cc4)nc32)n1 CHEMBL4846720 IC50 30.0 nM
CC(C)(O)c1cccc(-n2cc(F)c3cnc(Nc4ccc(N5C[C@@H]6C[C@H]5CN6)cc4)nc32)n1 CHEMBL4857055 IC50 30.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4574255 IC50 30.31 nM
COc1cc2ncn(-c3cc(OCc4ccccc4S(C)(=O)=O)c(C(N)=O)s3)c2cc1OC CHEMBL475215 IC50 31.0 nM
COc1cc2ncn(-c3cc(OCc4cccc(N(C)C)c4)c(C(N)=O)s3)c2cc1OC CHEMBL475616 IC50 31.0 nM
CCc1ccc2c(c1)NC(=O)Cc1cnc(Nc3ccc(OC)c(OC)c3)nc1-2 CHEMBL1944683 IC50 31.0 nM
COc1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=O)C3)cc1OC CHEMBL1947148 IC50 31.0 nM
O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 CHEMBL244378 pKi 31.62 nM
Cc1nn(-c2cc(Cl)cc(CCC(N)=O)c2)c2cc(N[C@@H](C)c3ccccc3)ncc12 CHEMBL525911 IC50 32.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(N4CCN(C)CC4)ccc3OC(F)(F)F)nc2N1C1CCCC1 CHEMBL3660143 IC50 32.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1ccccc1OCc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL3935387 IC50 32.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCC(N5CCCC5)CC4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1272250 IC50 33.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3CCN)CC4)c2)CC1 CHEMBL1774337 IC50 33.0 nM
COc1cc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=O)C3)cc(OC)c1 CHEMBL1944686 IC50 33.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(S(=O)(=O)NCCCO)cc3)nc2N1C1CCCC1 CHEMBL4169129 IC50 33.1 nM
C=CCOC(=O)/C(C#N)=C1\SC(CNc2ccc(C(C)=O)cc2)C(=O)N1CC CHEMBL477408 IC50 34.0 nM
COc1cc2ncn(-c3cc(OCC4CCCC4)c(C(N)=O)s3)c2cc1OC CHEMBL473630 IC50 34.0 nM
CCN1CCC(NC(=O)c2ccc(Nc3ncc4c(F)cn(-c5cccc(C(C)(C)O)n5)c4n3)cc2)CC1 CHEMBL4864046 IC50 34.0 nM
CCCNS(=O)(=O)c1ccc(Nc2ncc3c(n2)N(C2CCCC2)[C@H](CC)C(=O)N3C)cc1 CHEMBL4177399 IC50 34.72 nM
CCCCNC(=O)c1ccc(Nc2ncc3c(n2)N(C2CCCC2)[C@H](CC)C(=O)N3C)c(OCCO)c1 CHEMBL4453584 IC50 34.94 nM
COc1ccc(COc2cc(-n3cnc4ccccc43)sc2C(N)=O)cc1 CHEMBL474437 IC50 35.0 nM
NC(=O)c1sc(-c2cnc3ccccn23)cc1OCc1ccccc1Cl CHEMBL562764 IC50 35.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCN(C(=O)N5CCNCC5)CC4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1269488 IC50 35.0 nM
COc1cc(N(C)CCCO)ccc1Nc1ncc2c(n1)N(C1CCCC1)CCC(=O)N2C CHEMBL3917285 Kd 35.0 nM
CCCOC(=O)/C(C#N)=c1\s/c(=C/Nc2ccc(O)cc2)c(=O)n1CC CHEMBL477615 IC50 36.0 nM
O=C1Cc2cnc(Nc3ccc(C(=O)O)cc3)nc2-c2ccc(Cl)cc2N1 CHEMBL1945021 IC50 36.0 nM
COc1cc(N(C)CCO)ccc1Nc1ncc2c(n1)N(C1CCCC1)CCC(=O)N2C CHEMBL3968756 Kd 36.0 nM
CCOC(=O)/C(C#N)=c1\s/c(=C/Nc2ccc(NC(=O)NCCN3CCCC3)cc2)c(=O)n1CC CHEMBL477616 IC50 37.0 nM
CC[C@@H]1C(=O)Nc2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCCC1 CHEMBL4214823 IC50 37.2 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NCCN(C)C)cc3OCCO)nc2N1C1CCCC1 CHEMBL4449123 IC50 38.02 nM
CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O)[C@@H](C)OP(=O)(O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(N)=O CHEMBL4127627 IC50 38.99 nM
CC(Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1cc(CO)ccc1Cl CHEMBL557945 IC50 39.0 nM
CN(C)CCCc1cccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=O)C3)c1 CHEMBL1944642 IC50 39.0 nM
O=C1Cc2cnc(Nc3cccc(C(=O)O)c3)nc2-c2ccc(Cl)cc2N1 CHEMBL1944688 IC50 39.0 nM
CCN1CCC(Oc2ccc(Nc3ncc4c(F)cn(-c5cccc(C(C)(C)O)n5)c4n3)cc2)CC1 CHEMBL4854224 IC50 39.0 nM
COc1cc(Nc2ncc3c(C)nc(-c4ccccc4)n3n2)cc(OC)c1OC CHEMBL519715 IC50 40.0 nM
COc1cc(N2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1095717 IC50 40.0 nM
C[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC3CCCC3)nc2N1C1CCCC1 CHEMBL4207437 IC50 40.0 nM
CCCCNS(=O)(=O)c1ccc(Nc2ncc3c(n2)N(C2CCCC2)[C@H](CC)C(=O)N3C)cc1 CHEMBL4170176 IC50 40.7 nM
CCCNC(=O)c1ccc(Nc2ncc3c(n2)N(C2CCCC2)[C@H](CC)C(=O)N3C)c(OCCO)c1 CHEMBL4574072 IC50 40.74 nM
CCN(CC)CCNC(=O)c1c[nH]c2ccc(N/C=c3/s/c(=C(/C#N)C(=O)NCC(F)(F)F)n(CC)c3=O)cc12 CHEMBL475881 IC50 41.0 nM
C[C@@H](Nc1c(Nc2ccnc(Nc3ccc4c(c3)Cc3ccccc3-4)n2)c(=O)c1=O)C(C)(C)C CHEMBL2205445 Ki 41.0 nM
Cc1nn(-c2ccccc2C(N)=O)c2cc(N[C@@H](C)c3ccccc3)ncc12 CHEMBL496337 IC50 42.0 nM
COc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1094135 IC50 42.0 nM
CN(C)CCCN1CCC(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 CHEMBL1774329 IC50 42.0 nM
CN1CCN(c2ccc(Nc3ncc4c(=O)n(-c5cccc(OC(F)(F)F)c5)n(-c5cccc(C(C)(C)O)n5)c4n3)cc2)CC1 CHEMBL5277833 IC50 42.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3CCOC3CCOCC3)CC4)c2)CC1 CHEMBL1774338 IC50 43.0 nM
CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc4ncsc4c3)n2)c(=O)c1=O CHEMBL2205464 Ki 43.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1ccccc1-c1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL3954114 IC50 43.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(-n3ccc4cc(C(=O)NC5CCCC5)ccc43)nc2N1C1CCCC1 CHEMBL4175722 IC50 43.41 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(NC(=O)[C@@H]4CCCN4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1774330 IC50 44.0 nM
CCNC(=O)c1ncn2c1[C@@H](CC)N(C1CCCC1)c1nc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)ncc1-2 CHEMBL4085036 IC50 45.0 nM
CCOC(=O)/C(C#N)=c1\s/c(=C/Nc2cccc(C)c2)c(=O)n1CC CHEMBL503480 IC50 46.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CNC(C)(C)C)cc1F CHEMBL559888 IC50 46.0 nM
CN(C)CCCN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 CHEMBL3652223 IC50 46.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(S(=O)(=O)NCC(C)C)cc3)nc2N1C1CCCC1 CHEMBL4162262 IC50 46.58 nM
CNC(=O)c1c(F)cccc1Nc1nc(Nc2cc3c(cc2OC)CCN3C(=O)CN(C)C)nc2[nH]ccc12 CHEMBL464552 Kd 47.0 nM
C[C@H](Nc1c(Nc2ccnc(Nc3ccc(-c4ccccc4)cc3)n2)c(=O)c1=O)C(C)(C)C CHEMBL2205448 Ki 47.0 nM
CCOc1cc(N2CCC(O)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CCC(=O)N2C CHEMBL3974629 Kd 47.0 nM
CCC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC3CCCC3)nc2N1C1CCCC1 CHEMBL4209192 IC50 47.0 nM
Cc1nn(-c2cc(Cl)cc(CCC(=O)NCCO)c2)c2cc(N[C@@H](C)c3ccccc3)ncc12 CHEMBL498190 IC50 48.0 nM
CN1C(=O)CCN(C2CCCC2)c2nc(Nc3ccc(N4CCC(O)CC4)cn3)ncc21 CHEMBL3961803 Kd 49.0 nM
C[C@H](Nc1cc2c(cn1)cnn2-c1ccccc1C(N)=O)c1ccccc1 CHEMBL507529 IC50 50.0 nM
FC(F)(F)c1ccc(OC(CCNCc2ccccn2)c2ccccc2)cc1 CHEMBL3814827 IC50 50.0 nM
COC(=O)c1sccc1Nc1nc(Nc2ccc(N3CCC(N4CCCC4)CC3)cc2OC)ncc1F CHEMBL4777642 IC50 50.2 nM
C[C@H](Nc1cc2c(-c3cc(Cl)cc(CCC(N)=O)c3)noc2cn1)c1ccccc1 CHEMBL491021 IC50 51.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3cccc(C(F)(F)F)c3)ncc1CC2 CHEMBL1097424 IC50 51.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3CCCN)CC4)c2)CC1 CHEMBL1774339 IC50 52.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1ccccc1Oc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL3985321 IC50 52.0 nM
CC[C@@H]1C(=O)Nc2cnc(Nc3ccc(C(=O)NC4CCCC4)cc3OC)nc2N1C1CCCC1 CHEMBL4450564 IC50 52.06 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(S(=O)(=O)NC4CCCC4)cc3)nc2N1C1CCCC1 CHEMBL4173620 IC50 52.37 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NC4CCOCC4)cc3OCCO)nc2N1C(C)C CHEMBL4541823 IC50 52.61 nM
C[C@@H](Oc1cc(-n2cnc3ccc(-c4ccnc(Cl)c4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1208834 IC50 53.0 nM
COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(=O)N2C CHEMBL3609304 IC50 54.1 nM
O=C(Nc1ccc2cc(C(=O)Nc3nccs3)ccc2c1)c1ccc(Cl)c(Cl)c1 CHEMBL4445812 Kd 55.0 nM
Cc1nn(-c2cc(Cl)cc(CCCN)c2)c2cc(N[C@@H](C)c3ccccc3)ncc12 CHEMBL498191 IC50 59.0 nM
CN1CCC(NC(=O)c2ccc(Nc3ncc4ccn(-c5cccc(C(C)(C)O)n5)c4n3)cc2)CC1 CHEMBL4860891 IC50 59.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1269042 IC50 60.0 nM
CCN(CC)CCN(C)c1ccc(OC(F)(F)F)c(Nc2ncc3c(n2)-c2c(c(C(N)=O)nn2C)CC3)c1 CHEMBL1774331 IC50 60.0 nM
CC(C)(O)c1cccc(-n2cc(F)c3cnc(Nc4ccc(N5CCNCC5)cc4)nc32)n1 CHEMBL4876452 IC50 60.0 nM
NC(=O)c1sc(-n2cnc3ccccc32)cc1OCc1ccccc1 CHEMBL481724 IC50 61.0 nM
COc1cc2ncn(-c3cc(OCCCc4ccccc4)c(C(N)=O)s3)c2cc1OC CHEMBL516362 IC50 61.0 nM
CC(C)(O)c1cccc(-n2cc(F)c3cnc(Nc4ccc(N5CCNC6(CC6)C5)cc4)nc32)n1 CHEMBL4878853 IC50 61.0 nM
CCNC(=O)c1ccc2c(ccn2-c2ncc3c(n2)N(C2CCCC2)[C@H](CC)C(=O)N3C)c1 CHEMBL4171770 IC50 62.25 nM
CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl CHEMBL1993661 pKi 63.1 nM
CN1CCN(c2nc(C3=C(c4c[nH]c5ccccc45)C(=O)NC3=O)c3ccccc3n2)CC1 CHEMBL565612 pKi 63.1 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(S(N)(=O)=O)cc3)nc2N1C1CCCC1 CHEMBL4168155 IC50 64.77 nM
COc1ccc(Nc2ncc3c(n2)-c2ccc(C)cc2NC(=O)C3)cc1OC CHEMBL1944681 IC50 65.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(N)=O CHEMBL4126401 IC50 65.59 nM
CC(Oc1cc(-n2cnc3ccc(OC4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1 CHEMBL1689160 IC50 66.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3)ncc1CC2 CHEMBL559845 IC50 68.0 nM
CCOc1cc(C2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(Cc1sccc1C)[C@H](CC)C(=O)N2C CHEMBL4543331 IC50 68.0 nM
CN1CCC(Oc2ccc3ncn(-c4cc(OCc5ccccc5)c(C(N)=O)s4)c3c2)CC1 CHEMBL1689159 IC50 69.0 nM
COc1cc(Nc2ncc3c(C)nc(-c4cccc(Br)c4)n3n2)cc(OC)c1OC CHEMBL519375 IC50 70.0 nM
Cc1ccc(COc2cc(-n3cnc4ccccc43)sc2C(N)=O)cc1 CHEMBL454196 IC50 70.0 nM
C=CC[C@@H]1CN(C2CCCC2)c2nc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)ncc2N(C)C1=O CHEMBL2392557 IC50 70.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc4c(cc3OC)CCN4C(=O)CN3CCN(C(C)=O)CC3)nc2N1CC1CCCCC1 CHEMBL5422245 IC50 70.2 nM
CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccc([N+](=O)[O-])cc1)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O)[C@@H](C)OP(=O)(O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(N)=O CHEMBL4128878 IC50 70.24 nM
C#CNC(=O)/C(C#N)=c1\s/c(=C/Nc2ccc(OCCN(C)C)cc2)c(=O)n1CC CHEMBL514371 IC50 71.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1Cc1cccs1 CHEMBL4754471 IC50 71.0 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(-c4nnn[nH]4)s3)c2cc1OC CHEMBL520284 IC50 73.0 nM
CCn1c(=O)/c(=C\Nc2ccc(OCCN(C)C)cc2)s/c1=C(/C#N)C(=O)NCC(F)F CHEMBL515457 IC50 74.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O)[C@@H](C)OP(=O)(O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(N)=O CHEMBL4126831 IC50 74.14 nM
COc1cc2ncn(-c3cc(OCc4ccc(S(C)(=O)=O)cc4)c(C(N)=O)s3)c2cc1OC CHEMBL219899 IC50 75.0 nM
C[C@@H](Nc1c(Nc2ccnc(Nc3ccc(-c4ccccc4)cc3)n2)c(=O)c1=O)C(C)(C)C CHEMBL2205444 Ki 75.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)[C@@H](NC(C)=O)[C@@H](C)O)[C@@H](C)OP(=O)(O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(N)=O CHEMBL4129028 IC50 75.27 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 76.9 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(NC4CCNC4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1271591 IC50 77.0 nM
COc1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=O)C3)cc1 CHEMBL1944685 IC50 78.0 nM
COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)[C@H](CC(C)C)C(=O)N2C CHEMBL4215910 IC50 78.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccc(Cl)c(Cl)c1)NC(C)=O)[C@@H](C)OP(=O)(O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(N)=O CHEMBL4127785 IC50 78.42 nM
O=C1CCCN1Cc1ccc2c(c1)[nH]c(=O)c1cccn12 CHEMBL539474 pKi 79.43 nM
CCCNC(=O)c1ccc2c(ccn2-c2ncc3c(n2)N(C2CCCC2)[C@H](CC)C(=O)N3C)c1 CHEMBL4164012 IC50 79.84 nM
COc1cc(Nc2ncc3c(C)nc(-c4ccc(F)cc4)n3n2)cc(OC)c1OC CHEMBL471816 IC50 80.0 nM
CCOC(=O)/C(C#N)=c1\s/c(=C/Nc2ccc(C(C)=O)cc2)c(=O)n1CC CHEMBL476575 IC50 81.0 nM
COc1cc(C(=O)NC2CCN(C)CC2)cc(F)c1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C CHEMBL2392546 IC50 81.0 nM
CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4ccccn4)cc3)n2)c(=O)c1=O CHEMBL2205424 Ki 82.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(NC4CCCN4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1774332 IC50 83.0 nM
COc1ccc(Nc2ncc3c(n2)-c2ccc(C#N)cc2NC(=O)C3)cc1OC CHEMBL1944682 IC50 83.0 nM
CCOc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(Cc1ccccc1)[C@H](CC)C(=O)N2C CHEMBL4457809 IC50 84.0 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(C)=O)s3)c2cc1OC CHEMBL471789 IC50 85.0 nM
C[C@@H](Nc1c(Nc2ccnc(Nc3ccc4ccccc4c3)n2)c(=O)c1=O)C(C)(C)C CHEMBL2205443 Ki 85.0 nM
CCNc1cc(-c2ccc(NC(=O)Nc3cccc(Cl)c3)cc2C(F)(F)F)ccn1 CHEMBL4281348 IC50 85.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccccc1CO CHEMBL560206 IC50 88.0 nM
CN1CCN(c2ccc(Nc3ncc4c(=O)n(-c5cccc(Cl)c5)n(-c5cccc(C(C)(C)O)n5)c4n3)cc2)CC1 CHEMBL5269582 IC50 89.0 nM
COc1ccc(Nc2ncc3c(C)nc(-c4ccccc4)n3n2)cc1OC CHEMBL521204 IC50 90.0 nM
O=C(/C=C/c1ccccc1)NNC(=O)c1ccc2c(c1)OCCO2 CHEMBL3260249 IC50 90.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O)[C@@H](C)OP(=O)(O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(N)=O CHEMBL4130094 IC50 90.12 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCO/N=C\c1c(F)cccc1Oc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL3916818 IC50 91.0 nM
CC(Oc1cc(-c2cnc3cc(CO)ccn23)sc1C(N)=O)c1ccccc1Cl CHEMBL551422 IC50 92.0 nM
CSCC[C@H](NC(=O)c1ccc2c(c1)C1(OC2=O)c2ccc(O)cc2Oc2cc(O)ccc21)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)O)[C@@H](C)OP(=O)(O)O CHEMBL1809230 Kd 93.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(-n3ccc4cc(C(=O)NC)ccc43)nc2N1C1CCCC1 CHEMBL4163892 IC50 93.79 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCO/N=C/c1cccn1-c1nccc(-c2cccs2)n1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL3953093 IC50 94.0 nM
COc1cc(C(=O)N2CCCCC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)[C@H](C)C(=O)N2C CHEMBL4202678 IC50 95.0 nM
CSc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1094478 IC50 97.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(-n3ccc4cc(C(=O)NC(C)C)ccc43)nc2N1C1CCCC1 CHEMBL4174667 IC50 97.75 nM
C[C@H](Nc1cc2c(-c3cc(Cl)cc(CCCO)c3)noc2cn1)c1ccccc1 CHEMBL490814 IC50 99.0 nM
COc1cc2ncn(-c3cc(OCc4cccc(C#N)c4)c(C(N)=O)s3)c2cc1OC CHEMBL514040 IC50 99.0 nM
CCn1c(=O)/c(=C\Nc2ccc(CCN3CCCC3)cc2)s/c1=C(/C#N)C(=O)NCC(F)(F)F CHEMBL476136 IC50 100.0 nM
NC(=O)c1sc(-n2cnc3ccccc32)cc1OCc1ccc(Cl)cc1 CHEMBL481156 IC50 100.0 nM
CC(=O)c1cccc(Nc2ncc3c(n2)-c2c(c(C(N)=O)nn2C)CC3)c1 CHEMBL1099105 IC50 100.0 nM
CC[C@]1(F)CN(C2CCCC2)c2nc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)ncc2N(C)C1=O CHEMBL2392555 IC50 100.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3nccc(-c4cc5c(n4CCO)CCNC5=O)n3)c2)CC1 CHEMBL1933584 IC50 102.0 nM
CN1CCN(CCCNc2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 CHEMBL1774333 IC50 106.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1Cc1cccc(Br)c1 CHEMBL4755685 IC50 108.0 nM
CC(=O)c1ccc(N2CCN(C)CC2)cc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1095716 IC50 109.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(S(=O)(=O)Nc4ccccc4)cc3)nc2N1C1CCCC1 CHEMBL4165706 IC50 109.0 nM
Cn1nc(C(=O)O)c2c1-c1nc(Nc3ccccc3)ncc1CC2 CHEMBL1098060 IC50 110.0 nM
CNc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1095457 IC50 110.0 nM
CCOc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(Cc1cccc(Br)c1)[C@H](CC)C(=O)N2C CHEMBL4469756 IC50 110.0 nM
CN1CCN(c2ccc(Nc3ncc4c(=O)n(-c5cccc(C#N)c5)n(-c5cccc(C(C)(C)O)n5)c4n3)cc2)CC1 CHEMBL5273365 IC50 110.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3OC(F)(F)F)ncc1CC2 CHEMBL1272089 IC50 117.0 nM
CC(=O)N(c1ccccc1)c1nc(/C=N/OCCCCCn2cncc2C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]2CCCN2C(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O)cs1 CHEMBL3916430 IC50 119.0 nM
O=C1Cc2cnc(Nc3ccc(I)cc3)nc2-c2ccc(Cl)cc2N1 CHEMBL1945022 IC50 120.0 nM
COc1cccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=O)C3)c1 CHEMBL1944684 IC50 120.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(C)=O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O CHEMBL2380650 IC50 120.0 nM
O=C(/C=C/c1ccc([N+](=O)[O-])cc1)NNC(=O)c1ccc2c(c1)OCCO2 CHEMBL3260248 IC50 120.0 nM
Cc1nn(-c2cccc(Cl)c2)c2cc(N[C@@H](C)c3ccccc3)ncc12 CHEMBL478028 IC50 121.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(-n3ccc4cc(C(=O)NCC(C)C)ccc43)nc2N1C1CCCC1 CHEMBL4171224 IC50 121.5 nM
CC(=O)N1C[C@H](O/N=C/CCc2ccccc2)C[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL5194102 IC50 122.0 nM
CN1CCCC1CCNc1ccc(OC(F)(F)F)c(Nc2ncc3c(n2)-c2c(c(C(N)=O)nn2C)CC3)c1 CHEMBL1271535 IC50 123.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OCCO)nc2N1C(C)C CHEMBL4449490 IC50 123.8 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3F)ncc1CC2 CHEMBL1095771 IC50 125.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NN4CCN(C)CC4)cc3OC)nc2N1CC1CCCCC1 CHEMBL4749890 IC50 126.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCCC4)cc3OCCO)nc2N1C(C)C CHEMBL4473297 IC50 126.3 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NCCN(C)C)cc3OCCO)nc2N1C1CCCC1 CHEMBL4515755 IC50 126.8 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CC[N+](C)([O-])CC4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1271645 IC50 127.0 nM
C[C@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC3CCCC3)nc2N1C1CCCC1 CHEMBL4206381 IC50 127.0 nM
COc1cc2ncn(-c3cc(OCCc4ccccc4)c(C(N)=O)s3)c2cc1OC CHEMBL473629 IC50 130.0 nM
COc1cc2ncn(-c3cc(OCc4ccncc4)c(C(N)=O)s3)c2cc1OC CHEMBL475762 IC50 130.0 nM
NC(=O)c1sc(-c2cnn3ccccc23)cc1OCc1ccccc1C(F)(F)F CHEMBL559891 IC50 130.0 nM
N#CC[C@H](C1CCCC1)n1cc(-c2ncnc3[nH]ccc23)cn1 CHEMBL1789941 Kd 130.0 nM
CN(C)CCOc1cccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=O)C3)c1 CHEMBL1945168 IC50 130.0 nM
CN(C)CC1CC1c1cccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=O)C3)c1 CHEMBL1945030 IC50 130.0 nM
O=C(O)Cc1cn(CC(O)CN2CCCC2)c2ccccc12 CHEMBL3394764 IC50 130.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCO/N=C/c1cnc(N(C)Cc2ccccc2)s1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL3944369 IC50 133.0 nM
COc1cccc(Nc2ncc3c(n2)-c2c(c(C(N)=O)nn2C)CC3)c1 CHEMBL1095448 IC50 135.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1Cc1ccc(C(C)(C)C)cc1 CHEMBL4759383 IC50 138.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCCc1c(F)cccc1Oc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL3977234 IC50 139.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCc1ccccc1Oc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL3965583 IC50 139.0 nM
COc1ccc2c(c1)NC(=O)Cc1cnc(Nc3ccc(OC)c(O)c3)nc1-2 CHEMBL597393 IC50 140.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)NCCCCCCCc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL2207841 IC50 140.0 nM
COc1ccc(Nc2nccc(Nc3c(N[C@H](C)C(C)(C)C)c(=O)c3=O)n2)cc1 CHEMBL2205434 Ki 141.0 nM
NC(=O)c1nn(C2CCCCC2)c2c1CCc1cnc(Nc3ccccc3)nc1-2 CHEMBL1094402 IC50 143.0 nM
Cc1cc(C)cc(-n2nc(C)c3cnc(N[C@@H](C)c4ccccc4)cc32)c1 CHEMBL519858 IC50 149.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCO/N=C/c1cc(Cl)ccc1OCc1ccccn1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL3950880 IC50 149.0 nM
Cc1cc(CNC(C)(C)C)ccc1[C@@H](C)Oc1cc(-c2cnc3ccccn23)sc1C(N)=O CHEMBL557735 IC50 150.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3N)ncc1CC2 CHEMBL1097022 IC50 150.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1Cc1cccc(C(F)(F)F)c1 CHEMBL4793358 IC50 150.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3nccc(-c4cc(C(N)=O)cn4CCO)n3)c2)CC1 CHEMBL1933579 IC50 151.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)[C@@H](CO)C1 CHEMBL1774334 IC50 154.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1Cc1ccc(Br)cc1 CHEMBL4759851 IC50 154.0 nM
O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3[nH]ncc3c2)n1 CHEMBL396523 pKi 158.49 nM
CCOC(=O)/C(C#N)=c1\s/c(=C/Nc2ccccc2F)c(=O)n1CC CHEMBL476137 IC50 160.0 nM
COc1cc(C(=O)NC2CCCCC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)[C@H](C)C(=O)N2C CHEMBL4210414 IC50 160.0 nM
CN1CCN(c2ccc(Nc3ncc4c(=O)n(-c5ccccc5F)n(-c5cccc(C(C)(C)O)n5)c4n3)cc2)CC1 CHEMBL5289001 IC50 160.0 nM
CCCCNC(=O)c1ccc2c(ccn2-c2ncc3c(n2)N(C2CCCC2)[C@H](CC)C(=O)N3C)c1 CHEMBL4160611 IC50 161.6 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1Cc1ccc(Cl)cc1 CHEMBL4779839 IC50 162.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCO/N=C/c1c(F)cccc1Oc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL3944723 IC50 163.0 nM
CC(=O)N(c1ccccc1)c1nc(/C=N/OCCCCCCn2cncc2C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]2CCCN2C(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O)cs1 CHEMBL3909741 IC50 164.0 nM
C[C@@H](Nc1c(Nc2ccnc(Nc3ccc4c(c3)OCO4)n2)c(=O)c1=O)C(C)(C)C CHEMBL2205436 Ki 165.0 nM
CC(C)C(C)Nc1c(Nc2ccnc(Nc3ccc(-c4ccccc4)cc3)n2)c(=O)c1=O CHEMBL2205450 Ki 166.0 nM
COc1ccc(Cn2ncc(NC(=O)c3cc(NC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)ccc3C)c2N)cc1 CHEMBL1684800 IC50 167.4 nM
CCOc1ccc(CN2c3nc(Nc4ccc(C(=O)NC5CCN(C)CC5)cc4OC)ncc3-n3c(C)nnc3[C@H]2CC)cc1 CHEMBL4794106 IC50 169.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=O)CCCCCCCc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL2207840 IC50 170.0 nM
C=C[C@]1(F)CN(C2CCCC2)c2nc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)ncc2N(C)C1=O CHEMBL2392543 IC50 170.0 nM
CC(C)n1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2n1-c1cccc(C(C)(C)O)n1 CHEMBL5286445 IC50 170.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1Cc1cccc(Cl)c1 CHEMBL4751651 IC50 172.0 nM
CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)c(=O)c1=O CHEMBL2205463 Ki 175.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCOCC4)cc3OCCO)nc2N1C(C)C CHEMBL4469319 IC50 177.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCO/N=C/c1ccccc1-c1ccc(F)cc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL3979907 IC50 186.0 nM
COC(=O)c1sccc1Nc1nc(Nc2ccc(N3CCC(N(C)C)CC3)cc2OC)ncc1F CHEMBL4800439 IC50 188.5 nM
CCn1c(=O)/c(=C\Nc2cccc(NC(=O)C(C)(C)C)c2)s/c1=C(/C#N)C(=O)NC1(CO)CCCC1 CHEMBL476782 IC50 190.0 nM
COc1cc2ncn(-c3cc(OCc4ccoc4)c(C(N)=O)s3)c2cc1OC CHEMBL519286 IC50 190.0 nM
CC(Oc1cc(-n2cnc3ccc(OC4CCN(C)CC4)cc32)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1689164 IC50 190.0 nM
Cc1cc(Nc2ncc3c(n2)N(C2CCCC2)CC(F)(F)C(=O)N3C)ccc1C(=O)NC1CCN(C)CC1 CHEMBL2392551 IC50 190.0 nM
O=C(/C=C/c1ccccc1[N+](=O)[O-])NNC(=O)c1ccc2c(c1)OCCO2 CHEMBL3260236 IC50 190.0 nM
COc1ccc(/C=C/C(=O)NNC(=O)c2ccc3c(c2)OCCO3)cc1 CHEMBL3260247 IC50 190.0 nM
CC(=O)c1ccc(Nc2ncc3c(n2)-c2c(c(C(N)=O)nn2C)CC3)cc1 CHEMBL1099106 IC50 197.0 nM
Cc1nc2ccc(NS(=O)(=O)c3ccc(N)cc3)cc2nc1C CHEMBL2006263 pKi 199.53 nM
COc1ccc(Nc2nccc(Nc3c(NC(C)C(C)(C)C)c(=O)c3=O)n2)cc1OC CHEMBL1964399 pKi 199.53 nM
CNC(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCOCC3)cc2OC)ncc1Cl CHEMBL458997 pKi 199.53 nM
CN1CCC(Nc2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 CHEMBL1272300 IC50 200.0 nM
COc1ccc(Nc2ncc3c(n2)-c2ccc(F)cc2NC(=O)C3)cc1OC CHEMBL1944680 IC50 200.0 nM
CC(C)Oc1cc(N2CCC(O)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CCC(=O)N2C CHEMBL3938816 Kd 200.0 nM
COC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CC[C@H]2OCCNC(=O)CC[C@H](NC(=O)c3cc(OCC(C)C)cc(OCC(C)C)c3)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)OP(=O)(O)O)C(=O)N21 CHEMBL5082952 IC50 200.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)[C@H](CO)C1 CHEMBL1774335 IC50 201.0 nM
CC(=O)Nc1ccccc1-c1cc(Cl)cc(-n2nc(C)c3cnc(N[C@@H](C)c4ccccc4)cc32)c1 CHEMBL497167 IC50 207.0 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CNC(C)(C)C)cc1C1CC1 CHEMBL563989 IC50 210.0 nM
C[C@H](Nc1cc2c(-c3ccc4c(c3)OCO4)noc2cn1)c1ccccc1 CHEMBL522618 IC50 214.0 nM
COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C(C)C)[C@H](CC(C)C)C(=O)N2C CHEMBL4212237 IC50 218.0 nM
COC(=O)c1scc(C)c1Nc1nc(Nc2cc3c(cc2OC)CCN3C(=O)CN(C)C)ncc1[N+](=O)[O-] CHEMBL4793185 IC50 219.0 nM
C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O CHEMBL603469 Kd 220.0 nM
CN1CCC(C(=O)Nc2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 CHEMBL1774336 IC50 224.0 nM
Cc1nn(-c2cccc(S(C)(=O)=O)c2)c2cc(N[C@@H](C)c3ccccc3)ncc12 CHEMBL485295 IC50 225.0 nM
C=CCn1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2n1-c1ccc2c(n1)C(O)(CC)CC2 CHEMBL4871593 IC50 227.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(N)=O CHEMBL4760204 IC50 230.0 nM
C[C@@H](Nc1c(Nc2ccnc(Nc3ccc(F)cc3)n2)c(=O)c1=O)C(C)(C)C CHEMBL2205430 Ki 232.0 nM
COc1cc(Nc2nccc(Nc3c(N[C@H](C)C(C)(C)C)c(=O)c3=O)n2)cc(OC)c1OC CHEMBL2205427 Ki 234.0 nM
CCc1cccc(CC)c1NC(=O)c1nn(C)c2c1CCc1cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc1-2 CHEMBL1808340 IC50 237.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Oc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL3609315 Ki 240.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCO/N=C/c1cnc(N(C)Cc2ccccc2)s1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL3925420 IC50 244.0 nM
NC(=O)c1n[nH]c2c1CCc1cnc(Nc3ccccc3)nc1-2 CHEMBL1094401 IC50 248.0 nM
CS(=O)(=O)c1ccc2c(c1)ncn2-c1cc(OCc2ccccc2C(F)(F)F)c(C(N)=O)s1 CHEMBL519289 IC50 250.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(-c3cn[nH]c3-c3nccs3)nc2N1C1CCOCC1 CHEMBL2402083 IC50 250.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccccc3)nc2N1CCC(F)(F)F CHEMBL2401966 IC50 250.0 nM
CN1CCN(c2ccc(Nc3ncc4c(=O)n(C)n(-c5cccc(C(C)(C)O)n5)c4n3)cc2)CC1 CHEMBL5266086 IC50 250.0 nM
COc1cc2ncn(-c3cc(OCC4CCCO4)c(C(N)=O)s3)c2cc1OC CHEMBL220032 Log IC50 251.19 nM
OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1986943 pKi 251.19 nM
O=C(O)c1c2c(nc3ccccc13)C(=C1CCCC1)CC2 CHEMBL1996831 pKi 251.19 nM
C[C@@H](Nc1c(Nc2ccnc(Nc3ccc4c(c3)OCCO4)n2)c(=O)c1=O)C(C)(C)C CHEMBL2205437 Ki 255.0 nM
COc1ccc(Nc2ncc3c(n2)-c2c(c(C(N)=O)nn2C)CC3)cc1 CHEMBL1094322 IC50 256.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCSC)NC(=O)c1ccc2c(c1)C1(OC2=O)c2ccc(O)cc2Oc2cc(O)ccc21)[C@@H](C)OP(=O)(O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(N)=O CHEMBL1809231 Kd 256.0 nM
CN1CCN(c2ccc(Nc3ncc4c(n3)-c3ccc(Cl)cc3NC(=O)C4)cc2)CC1 CHEMBL1945024 IC50 260.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1Cc1ccsc1 CHEMBL4755667 IC50 266.0 nM
C[C@H](CC(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O)c1cncs1)NC(=O)c1ccc(CO)cc1 CHEMBL5175599 IC50 267.0 nM
CCn1c(=O)/c(=C\Nc2ccccc2)s/c1=C(/C#N)C(=O)N1CCCC1 CHEMBL476138 IC50 270.0 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3nccc(-c4cc(C(N)=O)cn4CCOC4CCCCO4)n3)c2)CC1 CHEMBL1933580 IC50 272.0 nM
C[C@@H](Nc1c(Nc2ccnc(Nc3ccc(Cl)cc3)n2)c(=O)c1=O)C(C)(C)C CHEMBL2205431 Ki 272.0 nM
Cc1nn(-c2cc(Cl)cc(Br)c2)c2cc(N[C@@H](C)c3ccccc3)ncc12 CHEMBL485497 IC50 274.0 nM
C[C@@H](Nc1c(Nc2ccnc(Nc3ccc(Oc4ccccc4)cc3)n2)c(=O)c1=O)C(C)(C)C CHEMBL2205447 Ki 276.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3Oc3ccccc3)ncc1CC2 CHEMBL1096095 IC50 278.0 nM
CN(C)CCCn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCN(C)CC4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1774340 IC50 279.0 nM
Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 CHEMBL1287853 Kd 280.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)[C@@H](C)OP(=O)(O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(N)=O CHEMBL4127365 IC50 283.3 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NN4CCN(C)CC4)cc3OC)nc2N1Cc1ccc(F)cc1 CHEMBL4794713 IC50 284.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(-n3ccc4cc(C(N)=O)ccc43)nc2N1C1CCCC1 CHEMBL4161572 IC50 284.2 nM
O=C1Cc2cnc(Nc3cccc(N4CCOCC4)c3)nc2-c2ccc(Cl)cc2N1 CHEMBL1945169 IC50 290.0 nM
CCOc1cc(C2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(Cc1ccccc1)[C@H](CC)C(=O)N2C CHEMBL4469087 IC50 290.0 nM
CC[C@@H]1C(=O)N(CCO)c2cnc(Nc3ccc(C(=O)NC4CCCC4)cc3OC)nc2N1C1CCCC1 CHEMBL4468970 IC50 291.6 nM
COc1ncc2cc3cnccc3c([N+](=O)[O-])c2n1 CHEMBL5181620 IC50 294.0 nM
COc1cccc(Nc2ncc3c(C)nc(-c4ccccc4)n3n2)c1 CHEMBL487977 IC50 300.0 nM
NC(=O)c1sc(-n2cnc3cc(C(F)(F)F)ccc32)cc1OCc1ccccc1Br CHEMBL480371 IC50 300.0 nM
C[C@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccccc1Cl CHEMBL550741 IC50 300.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(CCCCNC(=O)COc5cccc6c5C(=O)C(C5CCC(=O)NC5=O)C6=O)CC4)cc3OC)nc2N1CC1CCCCC1 CHEMBL5183703 IC50 310.0 nM
CCCCn1c2cc(OCc3ccc(F)cc3)ccc2c2cc[n+](Cc3ccccc3)c(C)c21 CHEMBL5280383 IC50 310.0 nM
C[C@@H](Nc1c(Nc2ccnc(Nc3cccc4ccccc34)n2)c(=O)c1=O)C(C)(C)C CHEMBL2205442 Ki 315.0 nM
CC(Nc1c(Nc2ccncc2)c(=O)c1=O)C1CCCCC1 CHEMBL1991577 pKi 316.23 nM
Cc1cccc(Nc2nccc(Nc3c(NC(C)C(C)(C)C)c(=O)c3=O)n2)c1 CHEMBL1969523 pKi 316.23 nM
CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(N3CCN(C(C)=O)CC3)ccc2OC)ncc1Br CHEMBL1971029 pKi 316.23 nM
CC1=NN(c2ccc(C(=O)O)cc2)C(=O)C1=Cc1c(C)c(C#N)c2nc3ccccc3n2c1O CHEMBL2006836 pKi 316.23 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cn(CCCCCCCCc2ccccc2)cn1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL2207844 IC50 320.0 nM
CCC1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1C1CCC(F)(F)C1 CHEMBL2401968 IC50 320.0 nM
O=P(O)(O)CC[C@H]1C2CCC(CC2)[C@@H]1Nc1nc(-c2c[nH]c3ncc(F)cc23)ncc1F CHEMBL3401977 Ki 320.0 nM
COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCOCC1)[C@H](CC(C)C)C(=O)N2C CHEMBL4207347 IC50 322.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCNC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCSC)NC(=O)c1ccc2c(c1)C1(OC2=O)c2ccc(O)cc2Oc2cc(O)ccc21)[C@@H](C)OP(=O)(O)O)[C@@H](C)O)[C@@H](C)O)C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(N)=O)C(C)C CHEMBL1809232 Kd 326.0 nM
CC(=O)N(C)c1cccc(Nc2nc(NCCc3cccs3)ncc2-c2nn[nH]n2)c1 CHEMBL478654 IC50 330.0 nM
Cc1cc(C)cc(-c2noc3cnc(N[C@@H](C)c4ccccc4)cc23)c1 CHEMBL489993 IC50 330.0 nM
C[C@@H](Nc1c(Nc2ccnc(Nc3cccc(-c4ccccc4)c3)n2)c(=O)c1=O)C(C)(C)C CHEMBL2205446 Ki 333.0 nM
NCCCc1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=O)C3)cc1 CHEMBL1945023 IC50 340.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1Cc1ccc(F)cc1 CHEMBL4785799 IC50 341.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCCC4)cc3OCCOC)nc2N1C1CCCC1 CHEMBL4587599 IC50 344.7 nM
CCNC(=O)/C(C#N)=c1\s/c(=C/Nc2cccc(C(=O)NCCCN3CCCC3)c2)c(=O)n1CC CHEMBL475946 IC50 345.0 nM
CC(=O)c1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1099104 IC50 346.0 nM
COc1ccc(Nc2ncc3c(n2)-c2ccc(OC)cc2NC(=O)C3)cc1 CHEMBL606395 IC50 350.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NN4CCN(C)CC4)cc3OC)nc2N1Cc1ccccc1 CHEMBL4747773 IC50 352.0 nM
C[C@@H](Nc1c(Nc2ccnc(Nc3ccc(Br)cc3)n2)c(=O)c1=O)C(C)(C)C CHEMBL2205432 Ki 354.0 nM
COc1ccc2c(c1)NC(=O)Cc1cnc(Nc3ccc(O)c(Cl)c3)nc1-2 CHEMBL597596 IC50 360.0 nM
CC(C)c1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1095772 IC50 365.0 nM
O=C1Cc2cnc(Nc3ccccc3)nc2-c2ccc(Cl)cc2N1 CHEMBL1944687 IC50 370.0 nM
Cc1nc(-c2ccccc2)n2nc(Nc3ccc(OCCN(C)C)cc3)ncc12 CHEMBL520692 IC50 380.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccccc3)nc2N1[C@H]1CCOC1 CHEMBL2401971 IC50 380.0 nM
CN1CCN(c2ccc(Nc3ncc4c(F)cn(-c5cccc(N=S(C)(C)=O)n5)c4n3)cc2)CC1 CHEMBL4873244 IC50 384.0 nM
CSc1ccccc1CNc1ncc([N+](=O)[O-])c(NCC2CCC(CN)CC2)n1 CHEMBL392642 pKi 398.11 nM
O=C(O)c1ccccc1Nc1ccnc(Nc2cccc(O)c2)n1 CHEMBL243088 pKi 398.11 nM
S=c1[nH]nc2c3c4c(sc3n3c(=S)[nH]nc3n12)CCC4 CHEMBL1969537 pKi 398.11 nM
NC(=O)c1sc2c([n+]1[O-])C(SC[C@H](N)C(=O)O)C(SC(F)(F)F)=CC2[N+](=O)[O-] CHEMBL4531713 IC50 400.0 nM
COc1cc(Nc2ncc3c(C)nc(-c4cccc(C(=O)c5ccccc5)c4)n3n2)cc(OC)c1OC CHEMBL519880 IC50 410.0 nM
O=C(O)Cc1cn(CC(O)CN2CCCCC2)c2ccccc12 CHEMBL3394763 IC50 410.0 nM
Cc1nn(-c2cccc(C#N)c2)c2cc(N[C@@H](C)c3ccccc3)ncc12 CHEMBL508139 IC50 412.0 nM
CCN(CC)S(=O)(=O)c1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=O)C3)cc1 CHEMBL1945027 IC50 420.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1Cc1ccoc1 CHEMBL4777694 IC50 426.0 nM
Cn1cncc1-c1cc(OCc2ccccc2C(F)(F)F)c(C(N)=O)s1 CHEMBL557878 IC50 430.0 nM
CC(C)n1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3)ncc1CC2 CHEMBL1094735 IC50 430.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3C(F)(F)F)ncc1CC2 CHEMBL1097071 IC50 432.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1Cc1ccccc1 CHEMBL4758654 IC50 434.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL2207846 Kd 445.0 nM
COc1ccc(Nc2ncc3c(n2)-c2ccccc2NC(=O)C3)cc1OC CHEMBL1944679 IC50 450.0 nM
COC(=O)c1ccc(Nc2ncc3c(n2)N(C2CCCC2)[C@H](C)C(=O)N3C)c(OC2CCCC2)c1 CHEMBL4212346 IC50 457.0 nM
CCCNS(=O)(=O)c1ccc(Nc2ncc3c(n2)N(c2ccn(C)n2)C(CC)C(=O)N3C)cc1 CHEMBL4168834 IC50 460.1 nM
CCCCNS(=O)(=O)c1ccc(Nc2ncc3c(n2)N(c2ccn(C)n2)C(CC)C(=O)N3C)cc1 CHEMBL4176689 IC50 461.6 nM
Cc1nn(-c2cccc(F)c2)c2cc(N[C@@H](C)c3ccccc3)ncc12 CHEMBL522392 IC50 464.0 nM
CC(=O)c1cc(N2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1096028 IC50 464.0 nM
C[C@@H](Nc1c(Nc2ccnc(Nc3ccccc3)n2)c(=O)c1=O)C(C)(C)C CHEMBL2205428 Ki 465.0 nM
COc1c(CCCN(C)C)cccc1Nc1ncc2c(n1)-c1ccc(Cl)cc1NC(=S)C2 CHEMBL1945802 IC50 470.0 nM
O=c1c2cc(F)ccc2n2c(=S)[nH]nc2n1CC1CC1 CHEMBL4786053 IC50 470.0 nM
Cc1cccc(-n2nc(C)c3cnc(N[C@@H](C)c4ccccc4)cc32)c1 CHEMBL497158 IC50 474.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccccc3)nc2N1[C@@H]1CCOC1 CHEMBL2401972 IC50 480.0 nM
CCCn1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2n1-c1cccc(C(C)(C)O)n1 CHEMBL5277502 IC50 480.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3[N+](=O)[O-])ncc1CC2 CHEMBL1094810 IC50 488.0 nM
FC(F)(F)c1ccc(Nc2nc(NCc3cccnc3)ncc2-c2nn[nH]n2)cc1 CHEMBL475947 IC50 490.0 nM
COc1cc(Nc2ncc3c(C)nc(-c4cccc(Oc5ccccc5)c4)n3n2)cc(OC)c1OC CHEMBL519881 IC50 500.0 nM
CCOC(=O)/C(C#N)=c1\s/c(=C/Nc2ccc(NC(=O)COC)cc2)c(=O)n1CC CHEMBL516582 IC50 500.0 nM
NC(=O)c1sc2c([N+](=O)[O-])cc(C(F)(F)F)cc2[n+]1[O-] CHEMBL476124 IC50 500.0 nM
CC(Oc1cc(-c2cc(-c3ccc(CN(C)C)s3)cnc2N)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL2042035 IC50 500.0 nM
COC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CC[C@H]2OCCNC(=O)CC[C@H](NC(=O)c3cc(OCCN(C)C)cc(OCC(C)C)c3)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)OP(=O)(O)O)C(=O)N21 CHEMBL5083531 IC50 500.0 nM
Cc1cc(Cl)ccc1NC(=S)NNC(=O)C(O)(c1ccccc1)c1ccccc1 CHEMBL1988173 pKi 501.19 nM
Clc1cc(-c2c[nH]c3ncccc23)nc(NC2CCCCC2)n1 CHEMBL2006439 pKi 501.19 nM
Clc1cc(NC2CCCCC2)nc(-c2c[nH]c3ncccc23)n1 CHEMBL1997846 pKi 501.19 nM
O=C1NCCc2[nH]c(-c3ccnc(C=Cc4ccccc4)c3)cc21 CHEMBL1997129 pKi 501.19 nM
CC(=NNC(=N)N)c1cc(NC(=O)c2cccc(C(=O)Nc3cc(C(C)=NNC(=N)N)cc(C(C)=NNC(=N)N)c3)c2)cc(C(C)=NNC(=N)N)c1 CHEMBL2000685 pKi 501.19 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1Cc1ccco1 CHEMBL4751396 IC50 505.0 nM
OCC(O)[C@H]1C2CCC(CC2)[C@@H]1Nc1nc(-c2c[nH]c3ncc(F)cc23)ncc1F CHEMBL3401984 Ki 510.0 nM
C=CCn1c(=O)c2cnc(Nc3ccc(N4CCN(CC(=O)NCCOCCOCCOCCOCCNc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)CC4)cc3)nc2n1-c1cccc(C(C)(C)O)n1 CHEMBL5403604 IC50 515.55 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NN4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL4796952 IC50 516.0 nM
O=C1Cc2cnc(Nc3cccc(C(=O)NCCN4CCOCC4)c3)nc2-c2ccc(Cl)cc2N1 CHEMBL1945028 IC50 520.0 nM
Cc1c2c(cc[n+]1Cc1ccccc1)c1ccc(OCc3ccccc3)cc1n2Cc1ccccc1 CHEMBL2164716 IC50 527.0 nM
CN1CCN(c2ccc(C(=O)Nc3n[nH]c4c3CN(C(=O)Cc3cccs3)C4)cc2)CC1 CHEMBL516110 IC50 530.0 nM
CCOc1cc(C2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(Cc1cccc(Br)c1)[C@H](CC)C(=O)N2C CHEMBL4451065 IC50 540.0 nM
CCOc1cc(C2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(Cc1cccc(Cl)c1)[C@H](CC)C(=O)N2C CHEMBL4448214 IC50 540.0 nM
Cc1cccc(-c2noc3cnc(N[C@@H](C)c4ccccc4)cc23)c1 CHEMBL489992 IC50 549.0 nM
CCCN(CC1CC1)c1nc(NC(C)c2ccccc2)ncc1C#N CHEMBL477393 IC50 550.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCO/N=C/c1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL3921057 IC50 558.0 nM
Nc1nccc(-c2cc3c([nH]2)[C@@H](CCF)CNC3=O)n1 CHEMBL524266 IC50 574.0 nM
COc1cccc(Nc2nc(NC(C)c3ccccc3)ncc2C#N)c1 CHEMBL477604 IC50 580.0 nM
O=C(/C=C/c1ccc(F)cc1)NNC(=O)c1ccc2c(c1)OCCO2 CHEMBL3260243 IC50 590.0 nM
C[C@@H](Nc1c(Nc2ccnc(Nc3ccc(OC(F)(F)F)cc3)n2)c(=O)c1=O)C(C)(C)C CHEMBL2205433 Ki 610.0 nM
C[C@H](Nc1cc2c(-c3cccc(Cl)c3)noc2cn1)c1ccccc1 CHEMBL523286 IC50 625.0 nM
COc1cc2ncn(-c3cc(OCc4ccc(S(C)(=O)=O)cc4)c(C#N)s3)c2cc1OC CHEMBL219711 Log IC50 630.96 nM
COc1cc2ncn(-c3cc(OCc4ccccc4)c(C(=O)O)s3)c2cc1OC CHEMBL222312 Log IC50 630.96 nM
NC(=O)c1cc2c(Oc3cccc(F)c3)cncc2s1 CHEMBL1964777 pKi 630.96 nM
COC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CC[C@H]2OCCNC(=O)CC[C@H](NC(=O)c3cccc(OCC(C)C)c3)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)OP(=O)(O)O)C(=O)N21 CHEMBL5089536 IC50 640.0 nM
Cc1nn(-c2cc(Cl)cc(Cl)c2)c2cc(N[C@@H](C)c3ccccc3)ncc12 CHEMBL485496 IC50 641.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(=O)CCCCCc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL2207839 IC50 650.0 nM
CCCCCCCCSc1ccc(C(=O)Nc2ccc(C)cc2C(=O)O)cc1 CHEMBL5093856 EC50 650.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C(=O)CCCCCCC(=O)Nc5cccc6c5CN(C5CCC(=O)NC5=O)C6=O)CC4)cc3OC)nc2N1CC1CCCCC1 CHEMBL5173742 IC50 652.0 nM
O=C(O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc12 CHEMBL1230165 Kd apparent 672.0 nM
CCC1C(=O)N(C)c2cnc(Nc3ccc(S(=O)(=O)NCCCO)cc3)nc2N1c1ccn(C)n1 CHEMBL4175615 IC50 673.5 nM
COc1ccc(Nc2ncc3c(C)nc(-c4ccccc4)n3n2)cc1 CHEMBL519257 IC50 680.0 nM
COC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CC[C@H]2OCCNC(=O)CC[C@H](NC(=O)[C@H](CCSC)NC(=O)[C@@H]3CCCN3)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)OP(=O)(O)O)C(=O)N21 CHEMBL5083550 IC50 680.0 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C#N)s3)c2cc1OC CHEMBL374440 IC50 700.0 nM
COc1ccc(-n2nc(C)c3cnc(N[C@@H](C)c4ccccc4)cc32)cc1 CHEMBL523233 IC50 703.0 nM
Cc1cc(NC(=O)/N=c2/[nH]cc(CCNc3cc(Nc4nc[nH]n4)ncn3)s2)c(C(F)(F)F)o1 CHEMBL1092830 IC50 720.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL4776770 IC50 724.0 nM
NC(=O)c1ccccc1Nc1ccnc(Nc2cccc(O)c2)n1 CHEMBL242237 IC50 730.0 nM
CN1CCN(Cc2cccc(Nc3ncc4c(n3)-c3ccc(Cl)cc3NC(=O)C4)c2)CC1 CHEMBL1945029 IC50 730.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(N(C)c3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL4583926 Km 730.0 nM
CCC1C(=O)N(C)c2cnc(Nc3ccc(S(=O)(=O)NC)cc3)nc2N1c1ccn(C)n1 CHEMBL4172511 IC50 742.0 nM
CC(Nc1ncc(C#N)c(N2CCc3ccccc3C2)n1)c1ccccc1 CHEMBL477605 IC50 750.0 nM
COc1ccc2c(c1)NC(=O)Cc1cnc(Nc3ccc(O)cc3)nc1-2 CHEMBL598418 IC50 750.0 nM
O=c1c2cc(F)ccc2n2c(=S)[nH]nc2n1CCC(F)(F)F CHEMBL4755597 IC50 750.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(-c3cn[nH]c3-c3nccs3)nc2N1C(C)C CHEMBL2401964 IC50 770.0 nM
COc1ccc(Nc2nccc(Nc3c(N[C@H](C)C(C)(C)C)c(=O)c3=O)n2)c(OC)c1 CHEMBL2205435 Ki 771.0 nM
Cc1cscc1-c1noc2cnc(N[C@@H](C)c3ccccc3)cc12 CHEMBL523634 IC50 779.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C(=O)CCCOc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)CC4)cc3OC)nc2N1CC1CCCCC1 CHEMBL5196738 IC50 788.0 nM
COc1cc2ncn(-c3cc(OCc4ccccc4S(C)(=O)=O)c(C#N)s3)c2cc1OC CHEMBL373751 Log IC50 794.33 nM
N#Cc1ncc2nc1OCCCCCOc1cc(OCCO)c(Cl)cc1NC(=O)N2 CHEMBL413779 pKi 794.33 nM
N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 CHEMBL1987034 pKi 794.33 nM
CC1=NN(c2ccccc2)C(=O)C1=Cc1c(C)c(C#N)c2nc3ccccc3n2c1O CHEMBL1999126 pKi 794.33 nM
CN1CCN(c2ccc(OC(F)(F)F)c(Nc3nccc(-c4cc5c(n4C)CCN(C(=O)OC(C)(C)C)C5=O)n3)c2)CC1 CHEMBL1933585 IC50 817.0 nM
C[C@@H](Oc1cc(-c2cc(-c3cc(CN(C)C)cs3)cnc2N)ccc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL2042136 IC50 820.0 nM
CCCCCCCCc1ccc(C(=O)Nc2ccc(C)cc2C(=O)O)cc1 CHEMBL5180726 EC50 820.0 nM
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC CHEMBL475251 Kd 830.0 nM
COCCOCCOCCOCCOc1cc(OCCOCCOCCOCCOC)cc(C(=O)N[C@H]2CCC(=O)NCCO[C@@H]3CC[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)OC)N3C(=O)[C@H]([C@@H](C)OP(=O)(O)O)NC(=O)[C@H](CO)NC2=O)c1 CHEMBL5078060 IC50 830.0 nM
COc1ccc2c(c1)NC(=O)Cc1cnc(Nc3cccc(O)c3)nc1-2 CHEMBL604912 IC50 840.0 nM
Cc1c2c(cc[n+]1Cc1ccccc1)c1ccc(OCc3ccc(F)cc3)cc1n2CCCc1ccccc1 CHEMBL5269742 IC50 854.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCN(C(=O)OC(C)(C)C)CC4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1269487 IC50 859.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccccc3)nc2N1C(C)C CHEMBL2401965 IC50 870.0 nM
O=c1c2cc(F)ccc2n2c(=S)[nH]nc2n1CCc1ccccn1 CHEMBL4755098 IC50 870.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccc(C(F)(F)F)cc3)ncc1CC2 CHEMBL1097429 IC50 872.0 nM
CCC1C(=O)N(C)c2cnc(Nc3ccc(S(=O)(=O)NCC(C)C)cc3)nc2N1c1ccn(C)n1 CHEMBL4165409 IC50 882.7 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCCC4)cc3OCc3ccccc3)nc2N1C1CCCC1 CHEMBL4454586 IC50 884.6 nM
O=c1c2cc(F)ccc2n2c(=S)[nH]nc2n1CCc1ccncc1 CHEMBL4755584 IC50 890.0 nM
COc1ccc2c3cc[n+](CCCc4ccccc4)c(C)c3n(Cc3cccc(Cl)c3)c2c1 CHEMBL5287676 IC50 897.0 nM
CC(=O)Nc1ccc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(=O)c3ccccc3)n2)cc1 CHEMBL1242101 IC50 900.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccccc3OC)nc2N1Cc1ccc(F)cc1 CHEMBL4793356 IC50 914.0 nM
N#Cc1ncc2nc1OCCCCCOc1cc(CCCO)c(Cl)cc1NC(=O)N2 CHEMBL223367 Ki 940.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3Cc3ccccc3)ncc1CC2 CHEMBL1094488 IC50 943.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3Nc3ccccc3)ncc1CC2 CHEMBL1094820 IC50 949.0 nM
CC(C)(C)c1ccc(Nc2nc(NCc3cccnc3)ncc2-c2nn[nH]n2)cc1 CHEMBL476145 IC50 960.0 nM
O=C(O)Cc1cn(CC(O)CN2CCOCC2)c2ccccc12 CHEMBL3394766 IC50 960.0 nM
COc1cccc(CC(=O)NCCCn2c(=O)c3cc(F)ccc3n3c(=S)[nH]nc23)c1 CHEMBL4782750 IC50 960.0 nM
CN1C(C)(C)CC(Nc2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1(C)C CHEMBL1271482 IC50 964.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccccc3OC)nc2N1Cc1cccc(C(F)(F)F)c1 CHEMBL4757681 IC50 975.0 nM
Cc1nn(-c2cccc(N(C)C)c2)c2cc(N[C@@H](C)c3ccccc3)ncc12 CHEMBL492055 IC50 977.0 nM
O=C1NCCc2[nH]c(-c3ccncc3)cc21 CHEMBL225519 IC50 980.0 nM
CC[C@@H]1c2nnc(C)n2-c2cnc(Nc3ccc(C(=O)NC4CCN(C(=O)COc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)CC4)cc3OC)nc2N1CC1CCCCC1 CHEMBL5177555 IC50 985.0 nM
N#Cc1ccc(CC(=O)NCCCn2c(=O)c3cc(F)ccc3n3c(=S)[nH]nc23)cc1 CHEMBL4779347 IC50 990.0 nM