CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL513909 IC50 1.61 nM
CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4ccncc4)cc3)n2)c(=O)c1=O CHEMBL2205426 Ki 2.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4noc(CN5CCCNCC5)n4)cc3OC)nc2N1C1CCCC1 CHEMBL5435085 IC50 4.89 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(N)n4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1208892 IC50 5.0 nM
COc1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)cc1CCCN(C)C CHEMBL1945502 IC50 5.0 nM
CN(C)CCCc1cc(Cl)cc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)c1 CHEMBL1945500 IC50 5.0 nM
CCC1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL1968380 pKi 5.012 nM
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC CHEMBL475251 Kd 5.1 nM
COc1cc2ncn(-c3cc(O[C@H](C)c4ccccc4Cl)c(C(N)=O)s3)c2cc1OC CHEMBL222419 IC50 6.0 nM
Cc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1094477 IC50 6.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209841 IC50 6.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1209842 IC50 6.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCCC4)cc3OC)nc2N1C1CCCC1 CHEMBL4592698 IC50 6.04 nM
O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 CHEMBL244378 pKi 6.31 nM
CN(C)CCCc1cc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)ccc1F CHEMBL1945501 IC50 7.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(-c4noc(CN5CCNCC5)n4)cc3OC)nc2N1C1CCCC1 CHEMBL5430344 IC50 7.56 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(N)=O)s3)c2cc1OC CHEMBL514499 pKi 7.943 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccncc4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209605 IC50 8.0 nM
COc1cc2ncn(-c3cc(OCc4ccccc4Cl)c(C(N)=O)s3)c2cc1OC CHEMBL514162 IC50 9.0 nM
CN(C)CCCc1cc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)ccc1C(F)(F)F CHEMBL1945801 IC50 9.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccncc4)ccc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1209674 IC50 10.0 nM
CNc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1095457 IC50 11.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)N[C@H]4CC[C@H](N5CCN(CC6CC6)CC5)CC4)cc3OC)nc2N1C(C)C CHEMBL1233528 EC50 11.0 nM
CN(C)CCCc1cccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)c1 CHEMBL1945170 IC50 12.0 nM
COc1cc(Nc2ncc([N+](=O)[O-])c(Nc3ccccc3C(N)=O)n2)cc(OC)c1OC CHEMBL1241473 pKi 12.59 nM
CCC1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCCCC4)cc3OC)nc2N1C1CCCC1 CHEMBL2005375 pKi 12.59 nM
COc1ccc(Nc2nccc(Nc3c(NC(C)C(C)(C)C)c(=O)c3=O)n2)cc1OC CHEMBL1964399 pKi 12.59 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3N)ncc1CC2 CHEMBL1097022 IC50 13.0 nM
COc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1094135 IC50 13.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(-c4cnn(C)c4)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1209843 IC50 13.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3)ncc1CC2 CHEMBL559845 IC50 14.0 nM
CS(=O)(=O)N(Cc1ccc2[nH]c(=O)c3cccn3c2c1)C1CC1 CHEMBL1978448 pKi 15.85 nM
Cc1cccc(Nc2nccc(Nc3c(NC(C)C(C)(C)C)c(=O)c3=O)n2)c1 CHEMBL1969523 pKi 15.85 nM
CSc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1094478 IC50 16.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(-c4ccncc4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209606 IC50 16.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4cccnc4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209676 IC50 16.0 nM
Cc1ccc(CCCN(C)C)cc1Nc1ncc2c(n1)-c1ccc(Cl)cc1NC(=S)C2 CHEMBL1945171 IC50 18.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCCC4)cc3C)nc2N1C1CCCC1 CHEMBL4454222 IC50 18.91 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NC4CCCC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4458460 IC50 22.14 nM
C[C@H](Nc1cc2c(-c3ccc4c(c3)OCO4)noc2cn1)c1ccccc1 CHEMBL522618 IC50 24.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(-c4ccncc4)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1209675 IC50 25.0 nM
O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3[nH]ncc3c2)n1 CHEMBL396523 pKi 25.12 nM
COc1cc(Nc2ncc3c(C)nc(-c4cccc(C(F)(F)F)c4)n3n2)cc(OC)c1OC CHEMBL520037 IC50 30.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCCC4)cc3O)nc2N1C1CCCC1 CHEMBL4548940 IC50 30.4 nM
CN(C)CCCc1cncc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)c1 CHEMBL1945803 IC50 31.0 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(=O)O)s3)c2cc1OC CHEMBL474432 pKi 31.62 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3OC(F)(F)F)ncc1CC2 CHEMBL1272089 IC50 32.0 nM
COc1ccc2ncn(-c3cc(O[C@H](C)c4ccccc4Cl)c(C(N)=O)s3)c2c1 CHEMBL493326 IC50 35.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3F)ncc1CC2 CHEMBL1095771 IC50 37.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(S(=O)(=O)NC)cc3)nc2N1C1CCCC1 CHEMBL4166771 IC50 38.52 nM
Cc1ccc(NC(=O)Nc2ccc(-c3csc4ncnc(N)c34)cc2)cc1C CHEMBL2000335 pKi 39.81 nM
C[C@@H](Oc1cc(-n2cnc3ccc(-c4cccnc4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209677 IC50 40.0 nM
COc1ccc2ncn(-c3cc(O[C@H](C)c4ccccc4C(F)(F)F)c(C(N)=O)s3)c2c1 CHEMBL522709 IC50 41.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NC)cc3OCCO)nc2N1C1CCCC1 CHEMBL4456400 IC50 43.78 nM
COc1cc2ncn(-c3cc(O[C@@H](C)c4ccccc4Cl)c(C(N)=O)s3)c2cc1OC CHEMBL521806 IC50 44.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NC(C)C)cc3OCCO)nc2N1C1CCCC1 CHEMBL4457656 IC50 45.07 nM
CCNC(=O)c1cc(OCCO)c(Nc2ncc3c(n2)N(C2CCCC2)[C@H](CC)C(=O)N3C)cc1F CHEMBL4570557 IC50 46.93 nM
COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O CHEMBL428496 IC50 48.0 nM
CC(=O)Nc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1097373 IC50 49.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4cccs4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209757 IC50 50.0 nM
CCN1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL1967560 pKi 50.12 nM
O=C(O)c1ccccc1Nc1ccnc(Nc2cccc(O)c2)n1 CHEMBL243088 pKi 50.12 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3Oc3ccccc3)ncc1CC2 CHEMBL1096095 IC50 51.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)N[C@H]4CC[C@@H](N5CCN(CC6CC6)CC5)CC4)cc3OC)nc2N1C(C)C CHEMBL5276995 IC50 56.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OC[C@@H](O)CO)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1794067 IC50 61.0 nM
O=C(Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCCC4=O)c3)n2)c1)c1c(F)cccc1F CHEMBL2006715 pKi 63.1 nM
Nc1ncnc2onc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c12 CHEMBL213505 pKi 63.1 nM
Nc1ncnc2scc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL1998585 pKi 63.1 nM
Cc1ncc(CCCN(C)C)cc1Nc1ncc2c(n1)-c1ccc(Cl)cc1NC(=S)C2 CHEMBL1945804 IC50 64.0 nM
COc1cc(N2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1095717 IC50 66.0 nM
C=CCn1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2n1-c1ccc2c(n1)C(O)(CC)CC2 CHEMBL4871593 IC50 70.0 nM
CN(C)CCCc1ccc(Cl)c(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)c1 CHEMBL1945172 IC50 73.0 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccccn4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209756 IC50 79.0 nM
Nc1ncc(-c2ccncc2)c2scc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL1970083 pKi 79.43 nM
O=C1CCCN1Cc1ccc2c(c1)[nH]c(=O)c1cccn12 CHEMBL539474 pKi 79.43 nM
O=C(O)c1c2c(nc3ccccc13)C(=C1CCCC1)CC2 CHEMBL1996831 pKi 79.43 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1Cc2c[n+](cn2CCCCCCCCc2ccccc2)CCCCCCNC(=O)[C@H]([C@@H](C)OP(=O)(O)O)NC(=O)[C@H](CO)NC1=O CHEMBL4278200 IC50 80.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(S(N)(=O)=O)cc3)nc2N1C1CCCC1 CHEMBL4168155 IC50 80.72 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCN(C(=O)N5CCNCC5)CC4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1269488 IC50 83.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NC4CCOCC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4441121 IC50 84.8 nM
COc1cc(Nc2ncc3c(C)nc(-c4ccccc4)n3n2)cc(OC)c1OC CHEMBL519715 IC50 90.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(C)=O)cc3OCCO)nc2N1C1CCCC1 CHEMBL4447251 IC50 91.93 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3C(F)(F)F)ncc1CC2 CHEMBL1097071 IC50 95.0 nM
Cc1cc(Cl)ccc1NC(=S)NNC(=O)C(O)(c1ccccc1)c1ccccc1 CHEMBL1988173 pKi 100.0 nM
Cc1nc2ccc(NS(=O)(=O)c3ccc(N)cc3)cc2nc1C CHEMBL2006263 pKi 100.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3nsc4ncnc(N)c34)cc2)c1 CHEMBL262433 pKi 100.0 nM
CC(=O)c1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1099104 IC50 103.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCCC4)cc3CCO)nc2N1C1CCCC1 CHEMBL4436925 IC50 112.8 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NC4CCN(C)CC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4459892 IC50 116.6 nM
COc1ncc2cc3cnccc3c([N+](=O)[O-])c2n1 CHEMBL5181620 IC50 117.0 nM
NC(=O)c1sc(-n2cnc3ccccc32)cc1OCc1ccccc1C(F)(F)F CHEMBL481491 pKi 125.89 nM
C[C@@H](Oc1cc(-n2cnc3cc(-c4ccc[nH]4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1209758 IC50 126.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1Cc2c[n+](cn2CCCCCCCCc2ccccc2)CCCCCNC(=O)[C@H]([C@@H](C)OP(=O)(O)O)NC(=O)[C@H](CO)NC1=O CHEMBL4281659 IC50 130.0 nM
COc1ccc(CCCN(C)C)cc1Nc1ncc2c(n1)-c1ccc(Cl)cc1NC(=S)C2 CHEMBL1945173 IC50 140.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC(C)C)cc3OCCO)nc2N1C1CCCC1 CHEMBL4448563 IC50 142.5 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(S(=O)(=O)NCCO)cc3)nc2N1C1CCCC1 CHEMBL4176983 IC50 145.6 nM
CC(C)c1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1095772 IC50 146.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCOCC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4519294 IC50 150.2 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1269042 IC50 154.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC)cc3OCCO)nc2N1C1CCCC1 CHEMBL4566834 IC50 157.4 nM
Cc1cccc(C2(c3cccc(C)c3)CC2C(=O)Nc2ccncc2)c1 CHEMBL1999496 pKi 158.49 nM
CCOc1cc(C2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(Cc1cc(C)cs1)[C@H](CC)C(=O)N2C CHEMBL4449858 Kd 160.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(N)=O)cc3OCCO)nc2N1C1CCCC1 CHEMBL4461041 IC50 162.8 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(S(=O)(=O)NCCCO)cc3)nc2N1C1CCCC1 CHEMBL4169129 IC50 165.3 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NCCN4CCOCC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4529398 IC50 166.1 nM
C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CNC(C)(C)C)cc1OC(F)F CHEMBL551079 IC50 178.0 nM
C=Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCN(C)CC4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1793896 IC50 182.0 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 182.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NCCN4CCN(C)CC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4447495 IC50 196.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3noc4ncnc(N)c34)cc2)c1 CHEMBL211378 pKi 199.53 nM
CCCNS(=O)(=O)c1ccc(Nc2ncc3c(n2)N(C2CCCC2)[C@H](CC)C(=O)N3C)cc1 CHEMBL4177399 IC50 203.9 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C(C)C)CC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4515187 IC50 205.2 nM
COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL509032 Kd 210.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(NC4CCNC4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1271591 IC50 239.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(NC4CCCN4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1774332 IC50 239.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(O[C@H]4CCCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1964264 IC50 240.0 nM
CCCCNS(=O)(=O)c1ccc(Nc2ncc3c(n2)N(C2CCCC2)[C@H](CC)C(=O)N3C)cc1 CHEMBL4170176 IC50 245.6 nM
C[C@@H](Oc1cc(-n2cnc3ccc(O[C@@H]4CCCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1964265 IC50 250.0 nM
CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl CHEMBL1993661 pKi 251.19 nM
CCn1c(C)c(-c2ccnc(Nc3cccc(OC)c3)n2)sc1=O CHEMBL1986263 pKi 251.19 nM
O=S(=O)(O)c1ccc(NCc2ccc3c(c2)OCO3)c2c(O)cccc12 CHEMBL2004544 pKi 251.19 nM
Cc1cccc(NC(=O)Nc2ccc(-c3coc4ncnc(N)c34)cc2)c1 CHEMBL1983963 pKi 251.19 nM
CN(C)CCCc1ccc(OC(F)(F)F)c(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)c1 CHEMBL1945497 IC50 260.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCN(C(=O)OC(C)(C)C)CC4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1269487 IC50 262.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OC4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1615278 IC50 270.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL2207845 IC50 280.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4ncnc(N)c34)cc2)c1 CHEMBL196363 pKi 316.23 nM
CC1=NN(c2ccc(Cl)c(Cl)c2)C(=O)C1=Cc1c(C)c(C#N)c2nc3ccccc3n2c1O CHEMBL1997349 pKi 316.23 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C)c5)cnc(N)c34)cc2)c1 CHEMBL1967116 pKi 316.23 nM
CN1CC=C(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 CHEMBL1774327 IC50 323.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(S(=O)(=O)NCC(C)C)cc3)nc2N1C1CCCC1 CHEMBL4162262 IC50 342.2 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OC4CCNCC4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1964263 IC50 350.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NCCN4CCOCC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4573833 IC50 366.3 nM
CCCNC(=O)c1ccc(Nc2ncc3c(n2)N(C2CCCC2)[C@H](CC)C(=O)N3C)c(OCCO)c1 CHEMBL4574072 IC50 385.3 nM
NC(=O)c1cc2c(-c3cccc(F)c3)cncc2s1 CHEMBL1971017 pKi 398.11 nM
COc1ccc(-c2ccc(NC(=O)Nc3cccc(Br)c3)cc2)c2c(N)noc12 CHEMBL271381 pKi 398.11 nM
S=c1[nH]nc2c3c4c(sc3n3c(=S)[nH]nc3n12)CCC4 CHEMBL1969537 pKi 398.11 nM
NC(=O)c1cc2c(-c3ccc(F)cc3)cncc2s1 CHEMBL1974310 pKi 398.11 nM
CCNC(=O)c1ccc(Nc2ncc3c(n2)N(C2CCCC2)[C@H](CC)C(=O)N3C)c(OCCO)c1 CHEMBL4545446 IC50 406.9 nM
CCC1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NC4CCCC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4465062 IC50 436.2 nM
CCCCNC(=O)c1ccc(Nc2ncc3c(n2)N(C2CCCC2)[C@H](CC)C(=O)N3C)c(OCCO)c1 CHEMBL4453584 IC50 440.6 nM
COc1ccc(N2CCN(C)CC2)cc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 CHEMBL1094408 IC50 450.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCCC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4531932 IC50 452.0 nM
O=C(Nc1ccc2cc(C(=O)Nc3nccs3)ccc2c1)c1ccc(Cl)c(Cl)c1 CHEMBL4445812 Kd 456.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OCCCN(C)C)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1964261 IC50 460.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4574255 IC50 476.7 nM
CCC1C(=O)N(C)c2cnc(Nc3ccc(S(=O)(=O)NCCO)cc3)nc2N1c1ccn(C)n1 CHEMBL4173322 IC50 482.8 nM
CN1CCCC1CCNc1ccc(OC(F)(F)F)c(Nc2ncc3c(n2)-c2c(c(C(N)=O)nn2C)CC3)c1 CHEMBL1271535 IC50 485.0 nM
NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 CHEMBL2001751 pKi 501.19 nM
N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 CHEMBL1987034 pKi 501.19 nM
Cc1cc(C)cc(NC(=O)Nc2ccc3c(c2)CCc2sc4ncnc(N)c4c2-3)c1 CHEMBL1964687 pKi 501.19 nM
O=C1NCCc2[nH]c(-c3ccncc3)cc21 CHEMBL225519 pKi 501.19 nM
CC1=NN(c2ccc(C(=O)O)cc2)C(=O)C1=Cc1c(C)c(C#N)c2nc3ccccc3n2c1O CHEMBL2006836 pKi 501.19 nM
Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1 CHEMBL1970317 pKi 501.19 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OCC4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1794068 IC50 550.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OCCO)nc2N1C1CCCC1 CHEMBL4450624 IC50 554.5 nM
N#Cc1ncc2nc1OCCCCCOc1cc(CCCO)c(Cl)cc1NC(=O)N2 CHEMBL223367 Ki 560.0 nM
Cc1c2c(cc[n+]1Cc1ccccc1)c1ccc(OCc3ccccc3)cc1n2Cc1ccccc1 CHEMBL2164716 IC50 607.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OC[C@H](O)CN4CCCC4)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1964262 IC50 610.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(OC4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1Cl CHEMBL1794070 IC50 630.0 nM
Cc1cc(C)cc(NC(=O)Nc2ccc(-c3c(C)sc4ncnc(N)c34)cc2)c1 CHEMBL371206 pKi 630.96 nM
N#CC1=C(N)n2c(sc(=Cc3ccco3)c2=O)=C(C(N)=O)C1c1ccco1 CHEMBL1989805 pKi 630.96 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cn[nH]c5)cnc(N)c34)cc2)c1 CHEMBL1969102 pKi 630.96 nM
N#CC(=Cc1ccc(O)c(O)c1)C(=O)NCc1ccccc1 CHEMBL1974157 pKi 630.96 nM
NC(=O)c1cc2c(-c3ccccc3)cncc2s1 CHEMBL1999556 pKi 630.96 nM
Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(Br)c4)cc3)c12 CHEMBL1976220 pKi 630.96 nM
Cc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c12 CHEMBL1970074 pKi 630.96 nM
O=C(Nc1cnc2[nH]cc(-c3ccccc3)c2c1)c1c(F)cccc1F CHEMBL1996979 pKi 630.96 nM
Nc1ncnc2sc(Br)c(-c3ccc(NC(=O)Cc4cccc(Cl)c4)cc3)c12 CHEMBL1980896 pKi 630.96 nM
CC1=NN(c2ccccc2)C(=O)C1=Cc1c(C)c(C#N)c2nc3ccccc3n2c1O CHEMBL1999126 pKi 630.96 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(NC(=O)[C@@H]4CCCN4)ccc3OC(F)(F)F)ncc1CC2 CHEMBL1774330 IC50 681.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NCCN(C)C)cc3OCCO)nc2N1C1CCCC1 CHEMBL4449123 IC50 699.6 nM
CN1CCC(C(=O)Nc2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 CHEMBL1774336 IC50 705.0 nM
N#CC[C@H](C1CCCC1)n1cc(-c2ncnc3[nH]ccc23)cn1 CHEMBL1789941 Kd 710.0 nM
CN1CCN(CCCNc2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 CHEMBL1774333 IC50 713.0 nM
C[C@@H](Oc1cc(-n2cnc3ccc(CN4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F CHEMBL1908394 Kd 740.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(S(=O)(=O)NC4CCCC4)cc3)nc2N1C1CCCC1 CHEMBL4173620 IC50 742.8 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NC4CCN(C)CC4)cc3OCCO)nc2N1C(C)C CHEMBL4442768 IC50 749.7 nM
CSc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(C)ns2)n1 CHEMBL1270795 IC50 785.0 nM
Fc1cnc(Nc2ccccc2)nc1Nc1ccccc1 CHEMBL491758 pKi 794.33 nM
N#Cc1ncc2nc1OCCCCCOc1cc(OCCO)c(Cl)cc1NC(=O)N2 CHEMBL413779 pKi 794.33 nM
N#Cc1ncc2nc1OCCCCCOc1cc(OCCCO)c(Cl)cc1NC(=O)N2 CHEMBL373598 pKi 794.33 nM
Cc1c(C=O)c(O)n2c(nc3ccccc32)c1C#N CHEMBL1989856 pKi 794.33 nM
O=c1[nH]sc2c1c(=O)c1cc(F)c(NCc3ccccc3)c(F)c1n2C1CC1 CHEMBL1991640 pKi 794.33 nM
CN(C)C(=O)Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 CHEMBL1986328 pKi 794.33 nM
NC(COc1cncc(-c2cc3ccncc3s2)c1)Cc1c[nH]c2ccccc12 CHEMBL1966524 pKi 794.33 nM
N#Cc1c(O)[nH]c(=O)c2c(=N)oc3ccc(Cl)cc3c12 CHEMBL1973711 pKi 794.33 nM
NC(=O)c1cc2c(-c3ccc(Br)c(F)c3F)cncc2s1 CHEMBL1999918 pKi 794.33 nM
COc1cc(-c2ccc3c(c2)Nc2ccc(C(=O)NCc4cccc(F)c4)cc2NC3=O)ccc1O CHEMBL2000832 pKi 794.33 nM
O=C(NNC(=S)Nc1ccc(Cl)cc1)C(O)(c1ccccc1)c1ccccc1 CHEMBL1966722 pKi 794.33 nM
CCOC(=O)C1=C(N)n2c(sc(=Cc3cccs3)c2=O)=C(C(N)=O)C1c1cccs1 CHEMBL2004365 pKi 794.33 nM
O=C(NNC(=S)Nc1ccc(F)cc1)C(O)(c1ccccc1)c1ccccc1 CHEMBL1975138 pKi 794.33 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1ccc(CCOCc2ccccc2)cc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL4065187 IC50 920.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1ccc(CCO)cc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O CHEMBL4092848 IC50 960.0 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1Cc2c[n+](cn2CCCCCCCCc2ccccc2)CCCCNC(=O)[C@H]([C@@H](C)OP(=O)(O)O)NC(=O)[C@H](CO)NC1=O CHEMBL4292295 IC50 970.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(F)c(C(=O)NC4CCOCC4)cc3OCCO)nc2N1C(C)C CHEMBL4541823 IC50 974.33 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1C[C@H](CCCCCCCCc2ccccc2)C(=O)NCCC[C@@H](C(N)=O)NC(=O)[C@H]([C@@H](C)OP(=O)(O)O)NC(=O)[C@H](CO)NC1=O CHEMBL5179633 IC50 980.0 nM
CC(Nc1c(Nc2ccncc2)c(=O)c1=O)C(C)(C)C CHEMBL1986186 pKi 1000.0 nM
CC(Nc1c(Nc2ccncc2)c(=O)c1=O)C1CCCCC1 CHEMBL1991577 pKi 1000.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)cc2)c1 CHEMBL220057 pKi 1000.0 nM
CC(=O)N(c1ccncc1)c1c(NC(C)C(C)(C)C)c(=O)c1=O CHEMBL2005899 pKi 1000.0 nM
COc1cc(-c2ccc3c(c2)Nc2ccc(CCOc4ccc(N5CCOCC5)cc4)cc2NC3=O)ccc1CC#N CHEMBL1985566 pKi 1000.0 nM
O=C1NCCc2[nH]c(-c3ccnc(C=Cc4ccccc4)c3)cc21 CHEMBL1997129 pKi 1000.0 nM
O=c1c(NCc2ccc(Cl)c(Cl)c2)c(Nc2ccncc2)c1=O CHEMBL1975900 pKi 1000.0 nM
O=C(NS(=O)(=O)c1ccc(NCCSc2ccc(O)cc2)c([N+](=O)[O-])c1)c1ccc(-c2ccc(F)cc2)cc1 CHEMBL1992645 pKi 1000.0 nM
NC(=O)c1cc2c(Oc3cccc(F)c3)cncc2s1 CHEMBL1964777 pKi 1000.0 nM
Cc1cc(C)cc(NC(=O)Nc2ccc(-c3cccc4snc(N)c34)cc2)c1 CHEMBL1976328 pKi 1000.0 nM
Nc1ncnc2sc3c(c12)-c1ccc(NC(=O)Nc2ccccc2)cc1CC3 CHEMBL1994693 pKi 1000.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cc(CO)ccc4F)cc3)c12 CHEMBL1985311 pKi 1000.0 nM
N#Cc1ncc2nc1OCCCCOc1cc(NCc3cncs3)c(Cl)cc1NC(=O)N2 CHEMBL248757 pKi 1000.0 nM
CCN(CC)C(=O)Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 CHEMBL1983195 pKi 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM