Cc1cc(-c2ccc(CC(=O)Nc3ccc(-c4cccnc4)cc3)cc2)ccn1 CHEMBL2139947 IC50 0.074 nM
Cc1cc(-c2ccc(OC(C)C(=O)Nc3ccc(-c4cnccn4)cn3)cc2)ccn1 CHEMBL3623895 IC50 0.11 nM
Cc1cc(-c2ccc(CCC(=O)Nc3ccc(-c4cnccn4)cn3)cc2)ccn1 CHEMBL3623894 IC50 0.19 nM
Cc1cc(-c2ccc(OC(=O)Nc3ccc(-c4cnccn4)cn3)cc2)ccn1 CHEMBL3623875 IC50 0.23 nM
Cc1ccc(-c2ncc(CC(=O)Nc3ccc(-c4cnccn4)cn3)cc2C)cn1 CHEMBL3623896 IC50 0.38 nM
Cc1cc(-c2ncc(CC(=O)Nc3ccc(-c4cnccn4)cn3)cc2C)ccn1 CHEMBL3188386 IC50 0.4 nM
Cn1c(=O)c2c(ncn2CC(=O)Nc2ccc(-c3ccsc3)cc2)n(C)c1=O CHEMBL4080208 IC50 0.4 nM
C[C@@H](C(=O)Nc1ccc(-c2ccsc2)cc1)n1cnc2c1c(=O)n(C)c(=O)n2C CHEMBL3633801 IC50 0.5 nM
Cc1cc(-c2ccc(SCC(=O)Nc3ccc(-c4cnccn4)cn3)cc2)ccn1 CHEMBL3623893 IC50 0.53 nM
Cc1cc(-c2ccc(N(C)CC(=O)Nc3ccc(-c4cnccn4)cn3)cc2)ccn1 CHEMBL3623892 IC50 0.67 nM
Cc1cc(-c2ccc(NCC(=O)Nc3ccc(-c4cnccn4)cn3)cc2)ccn1 CHEMBL3623891 IC50 0.96 nM
C[C@H](Nc1ccc(-c2ccnn2C)nc1)C(=O)Nc1ccc(-c2cccnc2)cn1 CHEMBL4088716 IC50 1.0 nM
C[C@H](Nc1ccc(-c2ccnn2C)nc1)C(=O)Nc1ccc(-c2ccccc2)cn1 CHEMBL4080842 IC50 1.0 nM
CN1C(=O)C2=C(C1=O)N(CC(=O)Nc1ccc(-c3ccccc3)cn1)CCC2 CHEMBL4096728 IC50 1.0 nM
CN1C(=O)C2=C(C1=O)N(CC(=O)Nc1ccc(-c3ccccc3)nn1)CCC2 CHEMBL4080021 IC50 1.0 nM
Cc1nccn1-c1ccc(OCC(=O)Nc2ccc(-c3ccccc3)cc2)cc1 CHEMBL4070649 IC50 2.0 nM
Cc1cc(-c2ccc(OC(=O)Nc3ccc(-c4cccnc4)cc3)cc2)ccn1 CHEMBL3623874 IC50 2.2 nM
N#Cc1ccc2cc(OCC(=O)Nc3ccc(-c4cnccn4)cn3)ccc2c1 CHEMBL3623887 IC50 2.7 nM
Cn1c(=O)c2c(ncn2CC(=O)Nc2ccc(-c3ccccc3)nn2)n(C)c1=O CHEMBL3633802 IC50 2.9 nM
Cn1nccc1-c1ccc(OCC(=O)Nc2ccc(-c3ccccc3)cc2)cc1 CHEMBL4099279 IC50 4.0 nM
Cc1cc(-c2ccc(OC(=O)Nc3ccc(-c4ccccc4)cc3)cc2)ccn1 CHEMBL3623873 IC50 5.0 nM
Cn1c(=O)c2c(nc3n2[C@H](CC(=O)Nc2ccc(-c4ccccc4)nn2)CC3)n(C)c1=O CHEMBL3633804 IC50 5.0 nM
C[C@H](Nc1ccc(-n2ccnc2)cc1)C(=O)Nc1ccc(-c2ccccc2)cn1 CHEMBL4084739 IC50 5.0 nM
CN1C(=O)C2=C(C1=O)N(CC(=O)Nc1ccc(-c3ccccc3)nc1)CCC2 CHEMBL4069295 IC50 6.0 nM
C[C@H](Oc1ccc(-n2ccnc2)cc1)C(=O)Nc1ccc(-c2ccccc2)cc1 CHEMBL4089128 IC50 7.0 nM
CN1C(=O)C2=C(C1=O)N(CC(=O)Nc1ccc(-c3cccnc3)cc1)CCC2 CHEMBL4104447 IC50 8.0 nM
CCCn1c(SCC(=O)Nc2nc3ccc(OC)cc3s2)nnc1-c1ccncc1 CHEMBL4540197 IC50 8.0 nM
CN1C(=O)C2=C(C1=O)N(CC(=O)Nc1ccc(-c3cncc(F)c3)nn1)CCC2 CHEMBL4066589 IC50 9.0 nM
C[C@H](Nc1ccc(-c2ccnn2C)nc1)C(=O)Nc1ccc(-c2cccnc2)nc1 CHEMBL4098880 IC50 10.0 nM
CN1C(=O)C2=C(C1=O)N(CC(=O)Nc1ccc(-c3cccnc3)nc1)CCC2 CHEMBL4096529 IC50 11.0 nM
O=C(CN1CCCC2=C1C(=O)N(C1CC1)C2=O)Nc1ccc(-c2cncc(F)c2)nn1 CHEMBL4095609 IC50 11.0 nM
CN1C(=O)C2=C(C1=O)N(CC(=O)Nc1ccc(-c3ccccc3)cc1)CCC2 CHEMBL4066796 IC50 12.0 nM
O=C(CN1CCCC2=C1C(=O)N(C1CC1)C2=O)Nc1ccc(-c2cccnc2)nn1 CHEMBL4087906 IC50 12.0 nM
Cc1ccc(-c2ccc(NC(=O)CN3CCCC4=C3C(=O)N(C3CC3)C4=O)nn2)cn1 CHEMBL4103356 IC50 12.0 nM
O=C(COc1ccc(-n2ccnc2)cc1)Nc1ccc(-c2ccccc2)cc1 CHEMBL4097104 IC50 15.0 nM
CN1C(=O)c2cccc(CC(=O)Nc3ccc(-c4nccs4)cc3)c2C1=O CHEMBL4061069 IC50 15.0 nM
CN1C(=O)C2=C(C1=O)N(CC(=O)Nc1ccc(-c3nccs3)cc1)CCC2 CHEMBL4094309 IC50 15.0 nM
CC(=O)N1CCc2ccc(OCC(=O)Nc3ccc(-c4cnccn4)cn3)cc2C1 CHEMBL3623889 IC50 24.0 nM
Cn1c(=O)c2c(ncn2CC(=O)Nc2ccc(-c3nccs3)cc2)n(C)c1=O CHEMBL4066798 IC50 24.0 nM
COc1cc(F)ccc1-n1c(SCC(=O)Nc2nc3ccc(C)cc3s2)nc2c(c1=O)SCC2 CHEMBL3633800 IC50 27.0 nM
CN1C(=O)C2=C(C1=O)N(CC(=O)Nc1ccc(-c3cccnc3)nn1)CCC2 CHEMBL4104257 IC50 29.0 nM
Cc1ccc(-c2ccc(NC(=O)CN3CCCC4=C3C(=O)N(C)C4=O)nn2)cn1 CHEMBL4075204 IC50 29.0 nM
O=C(COc1ccc2ccncc2c1)Nc1ccc(-c2cnccn2)cn1 CHEMBL3623879 IC50 30.0 nM
O=C(CNc1ccc(-n2ccnc2)cc1)Nc1ccc(-c2ccccc2)cc1 CHEMBL4081262 IC50 30.0 nM
Cc1cc(-c2cccc(SCC(=O)Nc3ccc(-c4cnccn4)cn3)c2)ccn1 CHEMBL3623878 IC50 40.0 nM
O=C(Nc1ccc(-c2ccccc2)cc1)[C@@H]1CCCN1c1ccc(-n2ccnc2)cc1 CHEMBL4096832 IC50 40.0 nM
O=C(COc1ccc(-c2cnco2)cc1)Nc1ccc(-c2ccccc2)cc1 CHEMBL4063419 IC50 42.0 nM
Cn1c(=O)c2c(nc3n2C(C(=O)Nc2ccc(-c4nccs4)cc2)CC3)n(C)c1=O CHEMBL4102043 IC50 42.0 nM
COc1ccc(-n2nc(C(=O)NCC(=O)Nc3nc4ccc(OC)cc4s3)c3ccccc3c2=O)cc1 CHEMBL1257063 IC50 60.0 nM
COc1ccc(-n2nc(CNCC(=O)Nc3nc4ccc(OC)cc4s3)c3ccccc3c2=O)cc1 CHEMBL4088085 IC50 60.0 nM
CN1C(=O)C2=C(C1=O)N(CC(=O)Nc1ccc(-c3ccccn3)cc1)CCC2 CHEMBL4086549 IC50 67.0 nM
CN1C(=O)C2=C(C1=O)N(CC(=O)Nc1ccc(-c3ccncc3)cc1)CCC2 CHEMBL4078705 IC50 72.0 nM
C[C@@H](Oc1ccc(-n2ccnc2)cc1)C(=O)Nc1ccc(-c2ccccc2)cc1 CHEMBL4060944 IC50 130.0 nM
Cc1ccc2nc(NC(=O)CSc3nc4c(c(=O)n3-c3ccccc3)SCC4)sc2c1 CHEMBL1257064 IC50 157.0 nM
Cc1cc(-c2cccc(NCC(=O)Nc3ccc(-c4cnccn4)cn3)c2)ccn1 CHEMBL3623877 IC50 164.0 nM
Cc1cc(-c2cccc(OCC(=O)Nc3ccc(-c4cnccn4)cn3)c2)ccn1 CHEMBL3623876 IC50 188.0 nM
CC(=O)N1CCN(c2ccc(OCC(=O)Nc3ccc(-c4cnccn4)cn3)cc2)CC1 CHEMBL3623890 IC50 483.0 nM
N#Cc1ccc(OCC(=O)Nc2ccc(-c3cnccn3)cn2)cc1 CHEMBL3623888 IC50 485.0 nM
C[C@@H](Nc1ccc(-n2ccnc2)cc1)C(=O)Nc1ccc(-c2ccccc2)cn1 CHEMBL4102661 IC50 689.0 nM
COc1ccc(Cn2c(SCC(=O)Nc3nc4ccc(C(F)(F)F)cc4s3)nc3c(c2=O)SCC3)cc1 CHEMBL4204681 IC50 710.0 nM